LOCUS       BGC0000138             19055 bp    DNA     linear   BCT 21-JUN-2005
DEFINITION  Streptomyces diastaticus polyketide rim gene cluster, partial
            sequence.
ACCESSION   BGC0000138
VERSION     BGC0000138
KEYWORDS    .
SOURCE      Streptomyces diastaticus
  ORGANISM  Streptomyces diastaticus
            Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
            Streptomyces; Streptomyces diastaticus group.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.2.0-924c3663(changed)
            Run date     :: 2022-11-07 16:46:43
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 19055
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     gene            <1..1897
                     /gene="rimB"
     source          1..19055
                     /db_xref="taxon:1956"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces diastaticus"
                     /strain="108"
     protocluster    1..19055
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[9396:14610]"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      9397..14610
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     protocluster    1..19055
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[9396:14610]"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      9397..14610
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
     cand_cluster    1..19055
                     /SMILES="NC([*])C(=O)CC(=O)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="chemical_hybrid"
                     /product="NRPS-like"
                     /product="T1PKS"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     subregion       1..19055
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0000138"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..19055
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS-like"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX))"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /subregion_numbers="1"
                     /tool="antismash"
     CDS             <1..1897
                     /NRPS_PKS="Domain: PKS_KR (190-365). E-value: 3e-62. Score:
                     201.6. Matches aSDomain: nrpspksdomains_rimB_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (457-542). E-value: 7.3e-33.
                     Score: 104.7. Matches aSDomain:
                     nrpspksdomains_rimB_PKS_PP.1"
                     /NRPS_PKS="Domain: PKS_Docking_Cterm (553-629). E-value:
                     1.2e-12. Score: 40.4. Matches aSDomain:
                     nrpspksdomains_rimB_PKS_Docking_Cterm.1"
                     /codon_start=2
                     /gene="rimB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     71.3; E-value: 1.5e-21)"
                     /gene_kind="biosynthetic-additional"
                     /note="type I polyketide synthase"
                     /product="RimB"
                     /protein_id="AAR16514.1"
                     /sec_met_domain="PP-binding (E-value: 2.5e-18, bitscore:
                     56.0, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 1.5e-63, bitscore:
                     203.5, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 1.4e-09,
                     bitscore: 27.0, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="RmlD_sub_bind (E-value: 6.7e-08, bitscore:
                     21.4, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="ITTGQLRTGDRDALFKVDWTGVALTGERADSLALLGKDTEGILDG
                     LALQPRTDLDDLAEAGDHDTVLVPPMAGGAGTVESVHAVAAEALGVIQAWLADERFAAS
                     RLVFVTRGAVSGEDLAGAAVWGLVRSAQSEHPGRFGLVDVEDDADAALIPQVLASDEPQ
                     LLIRGGEVLAARLARTEAQQPLGWDTSGTVLITGGTGGLGRIVARHLVAEHGVRSLLLV
                     SRRGPAAEGAEELVAELRDHGAEAVGEACDVTDAAAVADLVTRHKPTAVVHTAGVLDDG
                     VVESLTPERLASVLRPKVDAAWNLHEATKDLVLDAFVVFSSVAGTFGSAGQANYAAGNA
                     FLDALAHHRRTQGLPATSLAWGPWSQDSGMTGTLTDADVQRMARSGMPPLSAEEGVALF
                     DAALASGEPATVPARLDLAALRRQGEVVPLLRGLIRTSGRRTAAAATDGDAAAAFAQRL
                     TGLSAAEGREVVLDAVRGQVAAVLGHGGATEIDEDRAFLDLGFDSLTAVELRNRLSALT
                     GIRLPATLLFDYPTPAELVDHLQARIAPEPSFGPEALLGELERLEKGFGELVITEEVHE
                     QIAGRLEVLRAKWQALRDTAPAAGRDGSPADEDFDFESASDEEVFDLLDNELGLN"
     aSDomain        572..1096
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_rimB_PKS_KR.1"
                     /evalue="3.00E-62"
                     /label="rimB_PKS_KR.1"
                     /locus_tag="rimB"
                     /protein_end="365"
                     /protein_start="190"
                     /score="201.6"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: B1"
                     /tool="antismash"
                     /translation="GTVLITGGTGGLGRIVARHLVAEHGVRSLLLVSRRGPAAEGAEEL
                     VAELRDHGAEAVGEACDVTDAAAVADLVTRHKPTAVVHTAGVLDDGVVESLTPERLASV
                     LRPKVDAAWNLHEATKDLVLDAFVVFSSVAGTFGSAGQANYAAGNAFLDALAHHRRTQG
                     LPATSLAWGPWS"
     aSModule        572..1627
                     /domains="nrpspksdomains_rimB_PKS_KR.1"
                     /domains="nrpspksdomains_rimB_PKS_PP.1"
                     /incomplete
                     /locus_tags="rimB"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       575..676
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_rimB_0001"
                     /evalue="4.60E-11"
                     /label="PKSI-KR_m1"
                     /locus_tag="rimB"
                     /protein_end="225"
                     /protein_start="191"
                     /score="35.3"
                     /tool="antismash"
                     /translation="TVLITGGTGGLGRIVARHLVAEHGVRSLLLVSRR"
     CDS_motif       890..919
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_rimB_0002"
                     /evalue="1.20E-03"
                     /label="PKSI-KR_m3"
                     /locus_tag="rimB"
                     /protein_end="306"
                     /protein_start="296"
                     /score="12.2"
                     /tool="antismash"
                     /translation="PKVDAAWNLH"
     CDS_motif       941..1051
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_rimB_0003"
                     /evalue="1.20E-22"
                     /label="PKSI-KR_m4"
                     /locus_tag="rimB"
                     /protein_end="350"
                     /protein_start="313"
                     /score="72.5"
                     /tool="antismash"
                     /translation="LDAFVVFSSVAGTFGSAGQANYAAGNAFLDALAHHRR"
     aSDomain        1373..1627
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_rimB_PKS_PP.1"
                     /evalue="7.30E-33"
                     /label="rimB_PKS_PP.1"
                     /locus_tag="rimB"
                     /protein_end="542"
                     /protein_start="457"
                     /score="104.7"
                     /tool="antismash"
                     /translation="LTGLSAAEGREVVLDAVRGQVAAVLGHGGATEIDEDRAFLDLGFD
                     SLTAVELRNRLSALTGIRLPATLLFDYPTPAELVDHLQAR"
     aSDomain        1661..1888
                     /aSDomain="PKS_Docking_Cterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_rimB_PKS_Docking_Cterm.1"
                     /evalue="1.20E-12"
                     /label="rimB_PKS_Docking_Cterm.1"
                     /locus_tag="rimB"
                     /protein_end="629"
                     /protein_start="553"
                     /score="40.4"
                     /tool="antismash"
                     /translation="LLGELERLEKGFGELVITEEVHEQIAGRLEVLRAKWQALRDTAPA
                     AGRDGSPADEDFDFESASDEEVFDLLDNELG"
     gene            complement(2006..3133)
                     /gene="rimC"
     CDS             complement(2006..3133)
                     /codon_start=1
                     /gene="rimC"
                     /note="tyrosine phosphatase"
                     /product="RimC"
                     /protein_id="AAR16515.1"
                     /transl_table=11
                     /translation="MNSPSTAAVQTARRIAVSFVATVSAVGVTASFASAEPVAAPHTEA
                     GRHAAQAPRATRGIPFTQATVARQQDGSFTVSWKAPGAGSVTVYADGKVVAYGGAEATI
                     TVRRLPAADRQWFRLVPDEGDPLTLADRSLHLEGAANFRDVGGYRTADGRWVKMGVLYR
                     SPTPCTSSPTPTWIKLRRLGIRTDFDLRTPGERAKAPDRVPAGARYVVANVIGEENSAE
                     LPPTAEASERLMAESYRQFVVRPSAAKAYRSLFRMAAEPGSYPLLYHCSSGKDRTGWAT
                     AVLLTALGVDRETVMRDYLASNDYLAASNAAELAKQPPEIAARLKPVLETRAPYLNAAF
                     DEVEARFGTFGAYLREGLGLNAQELERLRAALLTD"
     regulatory      3355..3359
                     /gene="rimD"
                     /regulatory_class="ribosome_binding_site"
     gene            3355..5024
                     /gene="rimD"
     CDS             3375..5024
                     /codon_start=1
                     /gene="rimD"
                     /note="cholesterol oxidase"
                     /product="RimD"
                     /protein_id="AAR16516.1"
                     /transl_table=11
                     /translation="MIENQHLSRRRLLGLAALGGAAVAGMTTISVAPRAAAAGQGSPRA
                     GDGAFVPAVVIGTGYGAAVSALRLGEAGIPTLMLEMGQLWNKPADDGNIFCGMLKPDRR
                     SSWFKSRTEAPLGSFLWLDVINRNIDPYAGVLDKVHFDEMSVYVGRGVGGGSLVNGGMA
                     VVPKRSYFEEVLPRVDAAQMYDRYFPRANSMLKVNHIDKGWFEDTEWYKYARVSREQAG
                     KAGLSTTFVPNVYDFDHMRREADGTAPKSALAGEVIYGNNHGKQSLDKTYLAAALGTGK
                     VTIETLHQVKAIRRQPDGSYVLSVVQSDADGKTIAQKEIGCRHLFLGAGSLGSTELLVR
                     ARDTGTLPELNAEVGAGWGPNGNIMTGRANHVWNPTGAHQSSIPALGIDDWDNPAAPVF
                     AEIAPMPAGLETWVSLYLAITKNPERGTFVYDKATDRAKLRWTRDQNTPAVNAAKSLFD
                     RINKANTTMYRYDLFGSQLKNFSDDFSYHPLGGCVLGKATDLYGRVAGYQNLYVMDGAL
                     VPGSIGVNPFVTITALAERNIERIIAEDVKAA"
     regulatory      5242..5250
                     /gene="rimE"
                     /regulatory_class="ribosome_binding_site"
     gene            5242..6636
                     /gene="rimE"
     CDS             5254..6636
                     /codon_start=1
                     /gene="rimE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1062:glycosyltransferase, MGT family (Score: 124.5;
                     E-value: 1.1e-37)"
                     /gene_kind="biosynthetic-additional"
                     /note="glycosyl transferase"
                     /product="RimE"
                     /protein_id="AAR16517.1"
                     /transl_table=11
                     /translation="MESARRPILFVSLPEAGLANPLLVLAEELSRQDVPDLWFATDEPR
                     REDVKKISVGSPVEFASLGEVVPELSAVTWGDEVYREVTQSSRFKAHRAVIRHSYVPRA
                     QEEKFQKLAAVVDEIRPALIVVDCISSYGVELAMARKIPYVLSVPFTPSNVLTAFTPFA
                     KGYTPKDFPVPHTGLPYPMNLPQRVRNMLFKLRTLAMFCNPTMSKVLAEDNRRRKAHGL
                     GQMSPMARIDHADLVLCNSIAELDYPFDIPEKFRMVGTMVPPLPEAEQEDELSRWLDEQ
                     PSVVYAGFGTITRLTREQVHSMVEVARRLQGRHQVLWKLPSGQQHLLPPKESLPDNLRI
                     ENWVPSQLDVLAHPNVKLFFTHAGGNGYNEGVYFGKPLVVRPLWVDCYDQAVRGRDFGI
                     SLTLDRPRDLDVDDVVDKLTRVLETPSFRENAERLGALQRAAGGRAAAAEVILGHPALA
                     RA"
     regulatory      6674..6683
                     /gene="rimF"
                     /regulatory_class="ribosome_binding_site"
     gene            6674..7748
                     /gene="rimF"
     CDS             6690..7748
                     /codon_start=1
                     /gene="rimF"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056:DegT/DnrJ/EryC1/StrS aminotransferase (Score:
                     349.6; E-value: 3.6e-106)"
                     /gene_kind="biosynthetic-additional"
                     /note="aminotransferase"
                     /product="RimF"
                     /protein_id="AAR16518.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 6.2e-104,
                     bitscore: 337.6, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSFKYPVSRPALEGNELAYLTGAVEDGWISSQGPMVGRFERAFAD
                     YNGIAHGVSCSSGTAALTLALRALGIGPGDEVIVPEFTMIASAWAVTYTGATPVFVDCG
                     DDLNIDVTRIEEKITARTKAVMPVHIYGRRCDMDAIMDIAYQYNLRVVEDSAEAHGIRP
                     VGDIACYSLFANKIITAGEGGICLTDDPKLAGQMQHLRAMAFTKDHSFLHKKVAYNYRM
                     TAMQAAVALAQTERLDDILEVRRGIEKRYDEGLADVPGITLMPPRDVLWMYDLRAERRE
                     ELREFLAGESIETRLFFKPMSRQPMYFHPDWPSLKANTFAEDGLYLPTHTGLTAGDQDF
                     VIDRVRAFYGVG"
     regulatory      7759..7768
                     /gene="rimG"
                     /regulatory_class="ribosome_binding_site"
     gene            7759..9039
                     /gene="rimG"
     CDS             7777..9039
                     /codon_start=1
                     /gene="rimG"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007:cytochrome P450 (Score: 403.8; E-value:
                     1.2e-122)"
                     /gene_kind="biosynthetic-additional"
                     /note="cytochrome P450 monooxygenase"
                     /product="RimG"
                     /protein_id="AAR16519.1"
                     /sec_met_domain="p450 (E-value: 1.2e-22, bitscore: 69.8,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTHTEPAAPATCPVTGATAGATDTTDSTGHGTDPLVVDFPLRAPG
                     IPFPPPEYADYRDKKGLVLSHLPDGKRVWLVTRHEDVRAVLTNPAISSNPQHPGFPNVG
                     ETIGVPRQDQIPGWFVGMDSPEHDRFRKALIPEFTVRRVRAMKPAIERTVDAQLDAMLA
                     AGNTADLVADFTLPIPSLVISALLGVPPADREFFESRTRVLVSFRAYSDEDRLAAGKDL
                     MRYINRLIEIKKNWGGDDIVTRLLATGAIGAHEMSGVLMLLLIAGHETTANNIALGVVT
                     LLKNPQWIGDERAVEETLRFHSVADLVSLRVAVEDVEIAGQHIKAGEGIVPLVAAANHD
                     EELFACPHAFDPSRSARGHVAFGYGVHQCLGQNLVRVEMEVAYRKLFERIPNLRLDVPE
                     DGLNIKYDGVLYGLHELPVRW"
     regulatory      9109..9118
                     /gene="rimH"
                     /regulatory_class="ribosome_binding_site"
     gene            9109..9316
                     /gene="rimH"
     CDS             9125..9316
                     /codon_start=1
                     /gene="rimH"
                     /gene_functions="other (smcogs) SMCOG1265:ferredoxin
                     (Score: 89.1; E-value: 2.6e-27)"
                     /gene_kind="other"
                     /note="ferredoxin"
                     /product="RimH"
                     /protein_id="AAR16520.1"
                     /transl_table=11
                     /translation="MRITVDSDRCVGAGQCVLNAPAVFDQDDDGLVTLLAEPGADQEAA
                     AKLAGALCPSGAITVHEG"
     regulatory      9389..9394
                     /gene="rimA"
                     /regulatory_class="ribosome_binding_site"
     gene            9389..14610
                     /gene="rimA"
     CDS             9397..14610
                     /NRPS_PKS="Domain: AMP-binding (29-437). E-value: 1.2e-80.
                     Score: 262.9. Matches aSDomain:
                     nrpspksdomains_rimA_AMP-binding.1"
                     /NRPS_PKS="Domain: PKS_PP (547-636). E-value: 1.3e-22.
                     Score: 71.8. Matches aSDomain:
                     nrpspksdomains_rimA_PKS_PP.1"
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (662-1089). E-value:
                     1.2e-170. Score: 559.8. Matches aSDomain:
                     nrpspksdomains_rimA_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (1193-1495). E-value: 1.1e-100.
                     Score: 328.6. Matches aSDomain:
                     nrpspksdomains_rimA_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_PP (1579-1665). E-value: 2.2e-22.
                     Score: 71.0. Matches aSDomain:
                     nrpspksdomains_rimA_PKS_PP.2"
                     /codon_start=1
                     /gene="rimA"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     mod_KS"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 285.4; E-value:
                     1.3e-86)"
                     /gene_kind="biosynthetic"
                     /note="type I polyketide synthase"
                     /product="RimA"
                     /protein_id="AAR16521.1"
                     /sec_met_domain="AMP-binding (E-value: 1.8e-80, bitscore:
                     260.0, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 3e-12, bitscore:
                     36.6, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 2.3e-101, bitscore:
                     328.6, seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="mod_KS (E-value: 3.4e-217, bitscore:
                     710.8, seeds: 217, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVPVHTADYVIQPPTDAAEVRGGHTLPEVFETASRAAPDAVAIVD
                     GDRSRTWAQWRADVRALARGLQESGVGPGDVVAVRLPNSWEFQTLHLAVAAVGAVLLPV
                     HEGTPTAEVHALLTRAEPVLLVLSASGSEGTATARSLLESVPTLRGVLLAGASEAECEE
                     PGIGALDGLRAAWTGSEPRPVHLTPDMPLALIPSSGTTSARPKLCVHTHGGLLANTAAV
                     VADAADAFGGTVLTACPMTHLFGLQSLHTALFAARTQVLLTGWDVDRFLELAREHNPRV
                     VFAVPAQLRDIVARLARAGEPAGFAPHQVRTAGAALAPALAAQIRAALDCEPVVVWGMS
                     EIGTGTATRAHHPDGSVGEPVDGVRVRVVDEHGAECAAGETGELQYQGPAMFRGYFREP
                     ELTRSALTDDGWLRTGDIAAIDADGVVVLHGRAAEVIATGGRKFGATEIESLLAELAGL
                     GPLAVAGAPDDRLGEYPCLVVTDRADRTIGLTEVTAFLRRRGLADHKIPLELVTVRELP
                     FTPAGKLDRRALKEQLRTGLEATPVAARLGAVPPETAEEALELVRDCVGQVLGSSGDPA
                     GPAVGAPEFPDTEFRRLGLDSVLAVRLRNLLREETGLSLPVTLAFDFPTPRAVAHALAE
                     QNDPASAAASGKTAEEARRFPADEADPVAIVAMACRLPGGADSPDALWELLAGGTDAMR
                     PFPDDRGWDLDRLFDEDPDRPGTCYAREGGFLPGAGDFDAGFFGLSDHEATATDPQQRL
                     LLVAAWETFERAGIDPASLKGTRTGVFTGAMERGYGALASAVPSEWESTLTTGAANSAI
                     SGRIAYTYGLEGPALTVDTASSSSLVALHLACRSLRSGETDLALAGGVTVMATPAPFTH
                     FARLRALATDSRAKAYADTANGSAWAEGAGLLLLERLSDARRNGHRVLALVRGSAVNQD
                     GASNGLTAPSGPAQQRVIRQALADAGLTPRDVDAVEGHGTGTPLGDPIEAQALMATYGQ
                     ERPEGRPLWLGSVKSNLGHTQAAAGVVGVIKTVLALGRGVLPRTLHVETPSTKVDWSAG
                     AVRLLTEAQPWPQESGHTRRAGVSSFGLTGTNAHVILEEAPDGTQSAPGSEPADDTAVP
                     WVLSARSRTALREQARRLAEHVTAHPGLRTQDIAHALATTRTRHRHRAVVSGSDRDRML
                     SATAAFGRGERAADVTPLDSAPGGLAFVFSGQGGQHPGMGRGAAEAFPVFGEALREVCD
                     TLDPLLARPLTSVMWADADSEEATLLHNAEFSQPSLFALQVALYRLYESWGMAPDRLAG
                     HSAGEIAAAHVTGILTLQDACALVASRGRLISSLPVGGATVAVRISEDEVRGWLAEETT
                     GSVSIAAVNGPHSLVLSGAEAPLIALTDRLRDAGHKTHRIPMRVAAHSPLMDPILGEFR
                     AVVRTLAYGTPTIPLVSTVTGRPLTDEEARDPEHWVRHVRRPVRFKDAIGRLREERVTG
                     FLELGAEPLLTPMIDECLEAAGPQHGTAVVPSLSSGVPDRQILLSAAARVHTHGAPVDW
                     DAVLPGARPVDLPTYAFQRRRFWLAAGPGAAAEAGFVGAAIGAGAPAADAEEPSGLEAR
                     LAGLEDAEQDAYVRSLVLAETSAVLGGQEPLDSEGTHTFKEMGINSVNAVELRNRLIAA
                     TDLRLPATLVYDHPTPNAVVRLVRERLARPATAARDVDSVVAELESLLTAGAEVSAEAV
                     ARLKAMAAGRDGTTDTGSGGPLDLTSASDEDLFRLMDAEH"
     aSDomain        9484..10707
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_rimA_AMP-binding.1"
                     /evalue="1.20E-80"
                     /label="rimA_AMP-binding.1"
                     /locus_tag="rimA"
                     /protein_end="437"
                     /protein_start="29"
                     /score="262.9"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="FETASRAAPDAVAIVDGDRSRTWAQWRADVRALARGLQESGVGPG
                     DVVAVRLPNSWEFQTLHLAVAAVGAVLLPVHEGTPTAEVHALLTRAEPVLLVLSASGSE
                     GTATARSLLESVPTLRGVLLAGASEAECEEPGIGALDGLRAAWTGSEPRPVHLTPDMPL
                     ALIPSSGTTSARPKLCVHTHGGLLANTAAVVADAADAFGGTVLTACPMTHLFGLQSLHT
                     ALFAARTQVLLTGWDVDRFLELAREHNPRVVFAVPAQLRDIVARLARAGEPAGFAPHQV
                     RTAGAALAPALAAQIRAALDCEPVVVWGMSEIGTGTATRAHHPDGSVGEPVDGVRVRVV
                     DEHGAECAAGETGELQYQGPAMFRGYFREPELTRSALTDDGWLRTGDIAAIDADGVVVL
                     HGRAAEVIA"
     aSModule        9484..11304
                     /complete
                     /domains="nrpspksdomains_rimA_AMP-binding.1"
                     /domains="nrpspksdomains_rimA_PKS_PP.1"
                     /locus_tags="rimA"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       10528..10608
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_rimA_0001"
                     /evalue="9.00E-06"
                     /label="NRPS-A_a6"
                     /locus_tag="rimA"
                     /protein_end="404"
                     /protein_start="377"
                     /score="18.1"
                     /tool="antismash"
                     /translation="AGETGELQYQGPAMFRGYFREPELTRS"
     aSDomain        11038..11304
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_rimA_PKS_PP.1"
                     /evalue="1.30E-22"
                     /label="rimA_PKS_PP.1"
                     /locus_tag="rimA"
                     /protein_end="636"
                     /protein_start="547"
                     /score="71.8"
                     /tool="antismash"
                     /translation="AVPPETAEEALELVRDCVGQVLGSSGDPAGPAVGAPEFPDTEFRR
                     LGLDSVLAVRLRNLLREETGLSLPVTLAFDFPTPRAVAHALAEQ"
     aSDomain        11383..12663
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_rimA_PKS_KS.1"
                     /domain_subtype="Modular-KS"
                     /evalue="1.20E-170"
                     /label="rimA_PKS_KS.1"
                     /locus_tag="rimA"
                     /protein_end="1089"
                     /protein_start="662"
                     /score="559.8"
                     /tool="antismash"
                     /translation="VAIVAMACRLPGGADSPDALWELLAGGTDAMRPFPDDRGWDLDRL
                     FDEDPDRPGTCYAREGGFLPGAGDFDAGFFGLSDHEATATDPQQRLLLVAAWETFERAG
                     IDPASLKGTRTGVFTGAMERGYGALASAVPSEWESTLTTGAANSAISGRIAYTYGLEGP
                     ALTVDTASSSSLVALHLACRSLRSGETDLALAGGVTVMATPAPFTHFARLRALATDSRA
                     KAYADTANGSAWAEGAGLLLLERLSDARRNGHRVLALVRGSAVNQDGASNGLTAPSGPA
                     QQRVIRQALADAGLTPRDVDAVEGHGTGTPLGDPIEAQALMATYGQERPEGRPLWLGSV
                     KSNLGHTQAAAGVVGVIKTVLALGRGVLPRTLHVETPSTKVDWSAGAVRLLTEAQPWPQ
                     ESGHTRRAGVSSFGLTGTNAHVILEEAP"
     aSModule        11383..14391
                     /complete
                     /domains="nrpspksdomains_rimA_PKS_KS.1"
                     /domains="nrpspksdomains_rimA_PKS_AT.1"
                     /domains="nrpspksdomains_rimA_PKS_PP.2"
                     /locus_tags="rimA"
                     /monomer_pairings="mal -> mal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       11866..11913
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_rimA_0002"
                     /evalue="9.50E-05"
                     /label="PKSI-KS_m3"
                     /locus_tag="rimA"
                     /protein_end="839"
                     /protein_start="823"
                     /score="14.8"
                     /tool="antismash"
                     /translation="GPALTVDTASSSSLVA"
     CDS_motif       12289..12333
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_rimA_0003"
                     /evalue="3.50E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="rimA"
                     /protein_end="979"
                     /protein_start="964"
                     /score="10.1"
                     /tool="antismash"
                     /translation="VEGHGTGTPLGDPIE"
     CDS_motif       12394..12438
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_rimA_0004"
                     /evalue="1.50E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="rimA"
                     /protein_end="1014"
                     /protein_start="999"
                     /score="11.1"
                     /tool="antismash"
                     /translation="GSVKSNLGHTQAAAG"
     CDS_motif       12973..13017
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_rimA_0005"
                     /evalue="5.70E-04"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="rimA"
                     /protein_end="1207"
                     /protein_start="1192"
                     /score="12.6"
                     /tool="antismash"
                     /translation="FVFSGQGGQHPGMGR"
     aSDomain        12976..13881
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_rimA_PKS_AT.1"
                     /evalue="1.10E-100"
                     /label="rimA_PKS_AT.1"
                     /locus_tag="rimA"
                     /protein_end="1495"
                     /protein_start="1193"
                     /score="328.6"
                     /specificity="consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="VFSGQGGQHPGMGRGAAEAFPVFGEALREVCDTLDPLLARPLTSV
                     MWADADSEEATLLHNAEFSQPSLFALQVALYRLYESWGMAPDRLAGHSAGEIAAAHVTG
                     ILTLQDACALVASRGRLISSLPVGGATVAVRISEDEVRGWLAEETTGSVSIAAVNGPHS
                     LVLSGAEAPLIALTDRLRDAGHKTHRIPMRVAAHSPLMDPILGEFRAVVRTLAYGTPTI
                     PLVSTVTGRPLTDEEARDPEHWVRHVRRPVRFKDAIGRLREERVTGFLELGAEPLLTPM
                     IDECLEAAGPQHGTAVVPSLS"
     CDS_motif       13156..13218
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_rimA_0006"
                     /evalue="2.30E-03"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="rimA"
                     /protein_end="1274"
                     /protein_start="1253"
                     /score="11.3"
                     /tool="antismash"
                     /translation="AEFSQPSLFALQVALYRLYES"
     CDS_motif       13222..13341
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_rimA_0007"
                     /evalue="1.80E-16"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="rimA"
                     /protein_end="1315"
                     /protein_start="1275"
                     /score="52.2"
                     /tool="antismash"
                     /translation="GMAPDRLAGHSAGEIAAAHVTGILTLQDACALVASRGRLI"
     CDS_motif       13441..13479
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_rimA_0008"
                     /evalue="2.10E-03"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="rimA"
                     /protein_end="1361"
                     /protein_start="1348"
                     /score="11.4"
                     /tool="antismash"
                     /translation="AAVNGPHSLVLSG"
     CDS_motif       13705..13737
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_rimA_0009"
                     /evalue="7.20E-03"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="rimA"
                     /protein_end="1447"
                     /protein_start="1436"
                     /score="10.0"
                     /tool="antismash"
                     /translation="WVRHVRRPVRF"
     aSDomain        14134..14391
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_rimA_PKS_PP.2"
                     /evalue="2.20E-22"
                     /label="rimA_PKS_PP.2"
                     /locus_tag="rimA"
                     /protein_end="1665"
                     /protein_start="1579"
                     /score="71.0"
                     /tool="antismash"
                     /translation="LAGLEDAEQDAYVRSLVLAETSAVLGGQEPLDSEGTHTFKEMGIN
                     SVNAVELRNRLIAATDLRLPATLVYDHPTPNAVVRLVRERL"
     gene            complement(14688..16367)
                     /gene="orf1"
     CDS             complement(14688..16367)
                     /codon_start=1
                     /gene="orf1"
                     /note="transposase"
                     /product="ORF1"
                     /protein_id="AAR16522.1"
                     /transl_table=11
                     /translation="MSMRPSGPGEIPAETVRVARAAFAKGSLAIRVRDELGPMFRDEDF
                     ADLFASRGRPAWSPAGLALVSVLQFVDGLTDRQAAEAVRARIDFKYALGLELGDPGFDF
                     SVLSEFRDRLAGADGGRRVMDGVLVAAREKGLLKSAGRARTDSTHILSSARQLNWLELV
                     AETLRSALNALAQAAPGWLAEAAEPDWFRHYATRAEESRFPKGRARRDEVGLRIGRDGM
                     RLLEEVFATVAPHRLRALDEVEILRQVWVQHFHMVEGEVARRDPKDRPPGMMRLVTPYD
                     REARGSVKRDIMWDGYKVHLTEICEADAPNLITNVATTVATVSDSVMSQSIHAGLADRD
                     CLPGEHWVDAGYPTATQVLAARTEHGVALHGPMAANTSAQSAGPYGLDAFTVDWDQQQV
                     ACPGGVTTTQWYPRTDSKGLAVIRVRFRHSECRPCPHRHECVGSATGQRREIMLRHREE
                     HEIIRHSRAEQQTDAWKDRYKIRAGVEGSISQAVGRCGLRRSRYRGLTKTSLQHQLTGA
                     AINLARIDAHLTGTPRARTRTSHFAALCPAEMTLDGAQAGTE"
     gene            complement(16481..17843)
                     /gene="rimJ"
     CDS             complement(16497..17843)
                     /NRPS_PKS="Domain: PKS_ER (52-413). E-value: 4.8e-23.
                     Score: 73.6. Matches aSDomain:
                     nrpspksdomains_rimJ_PKS_ER.1"
                     /codon_start=1
                     /gene="rimJ"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028:crotonyl-CoA reductase / alcohol dehydrogenase
                     (Score: 331.2; E-value: 1.1e-100)"
                     /gene_kind="biosynthetic-additional"
                     /note="crotonyl-CoA reductase"
                     /product="RimJ"
                     /protein_id="AAR16523.1"
                     /sec_met_domain="ADH_N (E-value: 1.5e-09, bitscore: 27.4,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 5.5e-33, bitscore:
                     103.3, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEILNAIQAPDTTAADFAALPLPESYRAITVHKDETDMFEGLAG
                     CDKDPRKSLHLDEVAVPELGPGEALVAVMASSVNYNSVWTSIFEPLPTFGFLERYGRRS
                     ELAKRHDLPYHVIGSDLAGVVLRTGPGVTVWKPGDEVVAHCLSVELESADGHGDTMLDP
                     EQRIWGFETNFGGLAELALVKSNQLMPKPGHLTWEEAAASGLVNSTAYRQLVSRNGAGM
                     KVGDNVLIWGASGGLGSYATQLVLAGGGTPVCVVSNDQKAEICRSMGAEAVIDRNAEGY
                     RFWKDEQTQDPREWKRFGKRIRELTGGEDVDIVFEHPGRETFGASVFVTRKGGTVVTCA
                     STSGYQHQYDNRYLWMSLKRIVGSHFANYREAWEANRLIAKGRIHPTLSQTYPLRETGQ
                     AAYDVHRNLHQGKVGILALAPEEGLGVRDAEFRARHASAINRFRGTLED"
     CDS_motif       complement(16590..16655)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_rimJ_0002"
                     /evalue="4.10E+01"
                     /label="PKSI-ER_m5"
                     /locus_tag="rimJ"
                     /protein_end="418"
                     /protein_start="396"
                     /score="-2.6"
                     /tool="antismash"
                     /translation="TGQAAYDVHRNLHQGKVGILAL"
     aSDomain        complement(16605..17687)
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_rimJ_PKS_ER.1"
                     /evalue="4.80E-23"
                     /label="rimJ_PKS_ER.1"
                     /locus_tag="rimJ"
                     /protein_end="413"
                     /protein_start="52"
                     /score="73.6"
                     /tool="antismash"
                     /translation="SLHLDEVAVPELGPGEALVAVMASSVNYNSVWTSIFEPLPTFGFL
                     ERYGRRSELAKRHDLPYHVIGSDLAGVVLRTGPGVTVWKPGDEVVAHCLSVELESADGH
                     GDTMLDPEQRIWGFETNFGGLAELALVKSNQLMPKPGHLTWEEAAASGLVNSTAYRQLV
                     SRNGAGMKVGDNVLIWGASGGLGSYATQLVLAGGGTPVCVVSNDQKAEICRSMGAEAVI
                     DRNAEGYRFWKDEQTQDPREWKRFGKRIRELTGGEDVDIVFEHPGRETFGASVFVTRKG
                     GTVVTCASTSGYQHQYDNRYLWMSLKRIVGSHFANYREAWEANRLIAKGRIHPTLSQTY
                     PLRETGQAAYDVHRNLHQGKV"
     CDS_motif       complement(17115..17171)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_rimJ_0001"
                     /evalue="2.30E-03"
                     /label="PKSI-ER_m5"
                     /locus_tag="rimJ"
                     /protein_end="243"
                     /protein_start="224"
                     /score="10.7"
                     /tool="antismash"
                     /translation="GDNVLIWGASGGLGSYATQ"
     gene            complement(18149..18550)
                     /gene="rimK"
     CDS             complement(18149..18550)
                     /codon_start=1
                     /gene="rimK"
                     /note="acetyltransferase"
                     /product="RimK"
                     /protein_id="AAR16524.1"
                     /transl_table=11
                     /translation="MAITYEWRGDFENAAVNRLHAEGFGHRGLDIDWVAQVHRHSLGWV
                     CARRDRDGELVGFVNVAWDGGVHAFVLDTVVTADMRRSGIGAGLVAAAVGGARAARCEW
                     LHVDFDDELRTFYFDACGFQPTNAGLIAL"
ORIGIN
        1 gatcaccacc gggcagctcc ggaccggcga ccgtgacgcc ctcttcaagg tcgactggac
       61 cggcgtagcc ctcacgggcg agcgcgcgga ctccctcgcc ctgctcggca aggacaccga
      121 aggcatcctc gacggcctcg cgctccagcc ccgcacggat ctcgacgacc tcgcggaggc
      181 aggcgaccac gacaccgtgc tcgtcccgcc gatggccggg ggtgccggga cggtggagtc
      241 cgttcacgcc gtggcggccg aggcgctggg tgtgatccag gcgtggctgg cggatgagcg
      301 gttcgcggct tcgcgtctgg tgttcgtgac gcggggcgcg gtgtcgggtg aggatctcgc
      361 aggtgcggcg gtgtggggcc tggtgcggtc ggcgcagtcg gagcacccgg gccgcttcgg
      421 cctggtggac gtggaagacg acgccgatgc agcgctgata ccgcaggtat tggcatccga
      481 cgagccgcaa ctgctgatac gcggcggcga ggtgctggcg gcgcgcctgg cccgtacgga
      541 ggcccagcag cccctgggct gggacacctc cggcacggtg ttgatcaccg gtggtacggg
      601 gggtctcggc cgcatcgtcg cccggcacct ggtggcggag cacggggtac ggagtctgct
      661 gctggtcagc cgcaggggtc cggctgccga gggcgccgag gagttggtgg ccgagctgcg
      721 ggaccacggc gccgaggcgg tgggcgaggc atgcgacgta accgacgcgg cggccgtcgc
      781 cgacctcgtt acgcgtcaca agccgaccgc tgtggtgcat acggccggtg tcctggacga
      841 cggcgtggtg gagtcgctga cccccgagcg gctcgcgtcc gtactgcgcc cgaaggtcga
      901 tgcggcctgg aacctgcacg aggcgaccaa ggatctggtt ctggacgcgt tcgtggtgtt
      961 ctcctccgtg gccggcactt tcggcagcgc gggtcaggcc aactacgcgg ccggtaacgc
     1021 cttcttggac gctctcgctc accaccgccg gacgcagggc cttccggcca cgtcgctcgc
     1081 gtggggcccg tggtcccagg acagcggcat gaccggcacc ctcaccgacg ccgacgtcca
     1141 gcgcatggcc cgctcgggca tgccgccgct gtcggccgag gaaggcgtgg cgctgttcga
     1201 cgcggccctc gccagtgggg agcccgcgac cgtgcccgct cgcctcgacc tggcggccct
     1261 gcgccggcag ggcgaggtgg tcccgctgct gcgcggcctg atcaggacct cgggccggcg
     1321 tacggcggcg gccgcgaccg acggcgacgc cgcggccgcc ttcgcccagc ggctgaccgg
     1381 cctgtcggcg gcggaaggac gcgaggtcgt cctcgatgcc gtacgcggcc aggtcgcggc
     1441 cgttctggga cacggcgggg ccacggagat cgatgaggac cgtgccttcc tggacctcgg
     1501 tttcgactcc ctcaccgcgg tcgaactccg caaccggctg agtgccctca cgggaatccg
     1561 cctgccggcg acgctgctgt tcgactaccc gacgccggcg gaactcgtcg accacctcca
     1621 ggcccgcatc gcacccgagc cgtccttcgg cccggaagcg ctcctgggcg aactcgaaag
     1681 gctggagaag ggcttcggtg aactcgtcat caccgaggag gtgcacgagc agatagccgg
     1741 ccgcctggaa gtcctccggg cgaagtggca ggccctgcgg gacacggccc cggcggccgg
     1801 gcgcgacggc tccccggccg acgaggactt cgacttcgag tccgcctccg acgaggaggt
     1861 cttcgacctc ctcgacaacg aactcggcct gaactgacgg gacgagccga aagaaacgcc
     1921 ccctccccga tgtccgtcgg ggagggggcg tttcttttcc tgcgggccgg tgggccggcc
     1981 gacggctgcc ttgccggtca gccggtcagt cggtgagcag cgccgcccgc agccgctcca
     2041 gctcctgcgc gttcagcccc agcccctccc gcagataggc gccgaaggtg ccgaagcgcg
     2101 cctcgacctc gtcgaaggcg gcgttcaggt acggggccct ggtctccagg accggcttga
     2161 ggcgggcggc gatctcgggc ggctgcttgg ccagttcggc ggcgttgctt gcggcgagat
     2221 agtcgttgct ggccaggtag tcgcgcatga ccgtctcgcg gtccacgccg agggccgtga
     2281 ggaggacggc cgtcgcccag cccgtgcggt ccttgccgct ggagcagtga tagagcagcg
     2341 ggtacgagcc gggctcggcg gccatgcgga acagcgaacg gtaagccttg gcggccgagg
     2401 gcctgacgac gaactgccgg taggattcgg ccatcagccg ctcggacgcc tccgccgtgg
     2461 ggggcagttc ggcggagttc tcctcgccga tgacattggc gacgacatag cgtgcgcccg
     2521 ccggtacccg gtccggggcc ttggcccgct cgcccggcgt gcgcaggtcg aagtccgtac
     2581 ggatgcccag gcgccgcagc ttgatccagg tcggcgtcgg tgagcttgtg cagggcgtcg
     2641 gcgagcggta cagcacgccc atcttcaccc accggccgtc ggcggttcgg tagccgccca
     2701 cgtcacggaa gttggcggcg ccctccaggt gcagcgagcg gtcggcgagg gtgagcgggt
     2761 cgccctcgtc cggcacgagg cggaaccact gacggtcggc cgcgggcagc cggcgtacgg
     2821 tgatggtggc ctcggccccg ccgtatgcca cgaccttgcc gtcggcgtag acggtcacgg
     2881 aaccggcgcc gggcgctttc caggacacgg tgaaggaacc gtcctgctgt cgggccaccg
     2941 tggcctgggt gaacggaatc ccgcgcgtgg cacgcggcgc ctgcgccgcg tgccgtcccg
     3001 cttcggtgtg cggcgcggcg acgggctcgg ccgaggcgaa ggacgcggtg acccccacgg
     3061 ccgaaacggt ggcgacgaac gacacggcga tgcggcgggc ggtctgcacg gccgccgtgg
     3121 atggtgagtt catagccggg accgtacggc cggaaacagc acggaattac tagagcgggc
     3181 gcggcgggcc gagcgggggc caaaaggcga ccgcgcacac cgtaccttta acatttccct
     3241 tagtcttttg tgatcaggat gggggcgcgc ggcggcccgg ggccggtgga ccaggcccgc
     3301 attcttcttg gtggcgacgc cgcggaacag ccctgcgggg aaaaatcctg tggcgaaggt
     3361 tgggtactac cagcgtgatc gagaaccagc acctgtcacg gcgccgtctg ctcggactgg
     3421 ccgccctcgg cggcgccgcc gtcgccggaa tgaccacgat ttccgtcgcc ccgcgcgccg
     3481 cggccgccgg gcagggaagc ccgcgggccg gtgacggcgc gttcgtaccg gcggtggtga
     3541 tcggcaccgg ttacggtgcg gcggtctccg cgctgcggct cggcgaggcg ggaattccga
     3601 cgctcatgct cgaaatgggc cagctgtgga acaagccggc cgacgacggc aacatcttct
     3661 gcggaatgct caagcccgac cgcaggtcca gctggttcaa gtcgcgcacc gaagccccgc
     3721 tgggctcgtt cctgtggctg gatgtcatca accgcaacat cgacccgtac gcgggcgtcc
     3781 tcgacaaggt gcacttcgac gagatgtcgg tgtacgtggg acggggcgtc ggcggcggct
     3841 cgctggtcaa cggcggcatg gccgtcgtac cgaagcgctc gtacttcgaa gaggtcctcc
     3901 cacgggtgga cgccgcccag atgtacgacc ggtacttccc gcgcgccaac tccatgctca
     3961 aggtgaacca catcgacaag gggtggttcg aggacacgga gtggtacaag tacgcgcggg
     4021 tctcgcgcga gcaggcgggc aaggcgggcc tgagcaccac cttcgtcccc aacgtctacg
     4081 acttcgacca catgcggcgc gaggcggacg gcacggcgcc caagtcggcg ctggccggcg
     4141 aggtgatcta cggcaacaac cacggcaagc agagcctgga caagacctat ctggccgccg
     4201 cgctgggcac cggcaaggtc accatcgaga cgctgcacca ggtcaaggcg atccggcggc
     4261 agccggacgg cagctatgtg ctgtccgtgg tgcagagcga cgccgacggc aagaccatcg
     4321 cgcagaagga gatcggctgc cgccacctgt tcctcggcgc gggcagcctc ggctccaccg
     4381 aactgctggt gcgcgcccgc gacaccggca cgctgcccga gctgaacgcc gaggtcggcg
     4441 cgggctgggg ccccaacggc aacatcatga ccggccgcgc caaccacgtc tggaacccca
     4501 ccggggccca ccagtcctcg atccccgccc tgggcatcga cgactgggac aacccggcag
     4561 ccccggtctt cgcggagatc gcgccgatgc cggccggcct ggagacctgg gtcagcctct
     4621 acctggcgat caccaagaac cccgagcgcg gcaccttcgt ctacgacaag gccaccgacc
     4681 gggccaaact gcgctggacc cgggaccaga acacccccgc ggtcaacgcc gcgaagtcgc
     4741 tgttcgaccg gatcaacaag gccaacacga cgatgtaccg ctacgacctg ttcggttcgc
     4801 agctgaagaa cttctccgac gacttcagct accacccgct cggcggctgc gtcctgggca
     4861 aggccaccga cctctacggc cgcgtcgccg gctatcagaa cctctacgtc atggacggcg
     4921 cgctcgtgcc gggctccatc ggcgtcaacc ccttcgtgac catcacggcc ctcgccgagc
     4981 gcaacatcga gcggatcatc gcggaggacg tcaaggccgc gtaaccgtgc cccggtgacg
     5041 gctcgccccg gcgcgcgcgt ccgcgatccc ggccctcctc tcacgcggag ggccggttcg
     5101 ctgctgcccg gacacctcac cgccgccccg cacatcaccg cacaggctct aaggattttc
     5161 cggtgcacgg cgtgagatca atggacggtg cggccggtcg atccgcacgg ggtgtgctcg
     5221 ccgaaccctg ttcatcagcg cgaaagggaa tccatggaat ccgcccgacg gccgatcctc
     5281 ttcgtcagtc ttccggaggc cgggctggcc aatccgctgc tcgtcctggc cgaggaactc
     5341 tcccgccaag acgtgccgga tctctggttc gccaccgacg agccgcggcg cgaggacgtg
     5401 aagaagattt cggtggggtc tccggtggaa ttcgcctcac tgggcgaggt ggtccccgaa
     5461 ctgtcggccg tgacctgggg cgacgaggtg taccgggaag tcacccagtc gtcgcggttc
     5521 aaggcgcacc gcgcggtgat ccggcactcg tacgtgcccc gcgcgcagga ggagaagttc
     5581 cagaagctcg cggccgtcgt cgacgagatc cggccggcgc tgatcgtcgt cgactgcatc
     5641 agttcgtacg gcgtggagct ggccatggcg cggaagatcc cgtacgtgct cagcgtgccg
     5701 ttcaccccga gcaatgtgct gacggcgttc acccccttcg ccaagggcta caccccgaag
     5761 gacttccccg taccgcacac ggggctgccc tatccgatga atctcccgca gcgggtgcgc
     5821 aacatgctct tcaaactgcg gaccctcgcg atgttctgca accccacgat gagcaaggta
     5881 ctggccgagg acaaccggcg gcgcaaggcg cacgggctcg ggcagatgag cccgatggcg
     5941 cggatcgacc acgccgatct ggtgctgtgc aattccatcg ccgagctgga ctatcccttc
     6001 gacattccgg agaagttccg gatggtcggc acgatggtgc cgcccctgcc ggaggcggag
     6061 caggaggacg agctctcgcg gtggctggac gaacagccct cggtcgtcta cgcgggattc
     6121 ggaaccatca cccggctcac ccgggaacag gtccattcca tggtcgaggt ggcccgccgg
     6181 ctccaggggc ggcaccaggt gctgtggaaa ctgccctcgg gacagcagca cctgctgccg
     6241 ccgaaggaat ccctgccgga caatctccgt atcgagaact gggtcccttc gcagctcgat
     6301 gtcctcgcgc atccgaacgt gaagctgttc ttcacccacg ccggcggcaa cggctacaac
     6361 gaaggcgtgt atttcggcaa gccgctcgtg gtacggccgc tgtgggtgga ctgctacgac
     6421 caggccgtac gcggccggga tttcggcatc agcctgaccc tcgaccggcc ccgggacctc
     6481 gatgtcgacg acgtcgtcga caagctgacc cgagtgctcg aaaccccctc cttccgcgag
     6541 aacgcggagc ggctcggcgc cctgcagcgt gcggcgggcg gccgtgcggc cgctgccgag
     6601 gtgatcctcg gacacccggc cctggcccgg gcgtaacacc gcacgcacat ctgtccgtgg
     6661 accacgaaaa ggcaaggaag agacagcgga tgtcgttcaa gtatcccgtg tccaggcccg
     6721 ctctggaggg caacgagctg gcgtatctga ccggtgccgt cgaggacggg tggatttcct
     6781 cccagggccc gatggtcggg cggttcgagc gtgccttcgc cgactacaac ggcatcgcgc
     6841 acggcgtttc ctgttcctcg ggaacggcgg cgctcaccct cgcgctgcgg gcgctgggca
     6901 tcggcccggg ggacgaggtc atcgtcccgg aattcacgat gatcgcctcg gcatgggcgg
     6961 tcacctacac cggcgccacg cccgtgttcg tggactgcgg ggacgacctc aacatcgacg
     7021 tcacccgtat cgaggagaag atcacggcgc gcacgaaggc cgtgatgccg gtgcacatct
     7081 acggccggcg gtgcgacatg gacgcgatca tggacattgc gtaccagtac aacctgcggg
     7141 tcgtggagga cagcgccgaa gcgcacggca ttcggccggt cggtgacatc gcgtgctact
     7201 cgctgttcgc caacaaaatc atcacggcgg gggagggcgg tatctgcctc accgacgacc
     7261 cgaaactcgc cgggcagatg cagcacttgc gggccatggc gttcaccaag gaccacagtt
     7321 tcctgcacaa gaaggtggcg tacaactacc gcatgacggc catgcaggcc gccgtcgcgc
     7381 tcgcccagac cgagcgcctg gacgacatcc tcgaagtgcg ccgcggaatc gagaagcgct
     7441 acgacgaggg gctggccgat gtccccggta tcacgctgat gccgccgcgg gacgtgctgt
     7501 ggatgtacga cctgcgcgcc gaacgccgcg aggaactgcg ggaattcctg gccggggagt
     7561 ccatcgagac ccggctgttc ttcaagccga tgagccggca gcccatgtac ttccaccccg
     7621 actggccctc gctcaaggcg aacaccttcg ccgaggacgg actgtacctg cccacccaca
     7681 ccggactgac cgccggcgac caggacttcg tgatcgaccg ggtccgcgcc ttctacggcg
     7741 tcggctgacg gcccgtccga aaggggaatt ccacccatga cgcacaccga accggccgcg
     7801 ccggccacct gcccggtcac gggagcgacg gccggggcca cggacacgac ggattcgacc
     7861 gggcacggaa cggacccgct ggtcgtcgac tttccgctgc gcgcgcccgg catacccttc
     7921 ccgccgcccg aatacgccga ttaccgcgac aagaaggggc tggtgctctc gcacctgccc
     7981 gacggcaaac gggtgtggct ggtcacccgg cacgaggacg tacgcgccgt cctgaccaac
     8041 ccggccatca gctccaaccc ccagcacccg ggctttccca atgtcggcga gacgatcggc
     8101 gtacccaggc aggaccagat acccggctgg ttcgtgggaa tggactcgcc cgaacacgac
     8161 cggttccgca aggccctcat cccggagttc accgtgcggc gcgtccgcgc gatgaaaccc
     8221 gcgatcgagc gcacggtgga cgcgcaactg gacgcgatgc tggccgcggg caacaccgcc
     8281 gacctcgtcg ccgacttcac cctgcccatt ccctccctgg tgatctcggc actgctcggc
     8341 gtgccgcccg ccgaccgcga gttcttcgaa tccaggaccc gcgtcctggt ctcgttccgt
     8401 gcgtactccg acgaggaccg cctggccgcc ggcaaggacc tcatgcggta catcaaccgg
     8461 ctgatcgaga tcaagaagaa ctggggcggc gacgacatcg tcacccggct gctggccacc
     8521 ggcgccatcg gtgcccacga aatgtccggc gtactgatgc tgctgctcat cgccggccac
     8581 gagaccacgg ccaacaacat cgcgctcggt gtggtcaccc tgctgaagaa tccccagtgg
     8641 atcggtgacg aacgggccgt cgaggaaacc ctgcgcttcc actcggtcgc cgacctggtg
     8701 tccctgcggg tggccgtcga ggacgtggag atcgccgggc agcacatcaa ggcgggcgag
     8761 ggcatcgtgc cgctggtcgc cgccgccaat cacgacgagg aactcttcgc gtgcccccac
     8821 gcgttcgacc cctcccgctc cgcccgcggc catgtggcct tcggctacgg cgtacaccag
     8881 tgcctggggc agaacctggt acgggtcgag atggaggtcg cgtaccgcaa gctcttcgag
     8941 cgcattccca acctccggct cgacgtgccc gaggacggac tgaacatcaa gtacgacggc
     9001 gtgctctacg gcctgcacga gctgcccgtc cgctggtgac ctgaccagag aacccgcgcc
     9061 cgcccggcgg cacgcctcac cggccgccgg gcggccccca tccaccgcag gagagaaacc
     9121 cgacatgcgt atcaccgttg actccgaccg ctgcgtcggg gcgggccagt gcgtactgaa
     9181 cgcgcccgcg gtcttcgacc aggacgacga cgggctcgtc acccttctcg ccgagcccgg
     9241 cgccgaccag gaggccgccg ccaaactggc cggtgccctg tgcccgtccg gggccatcac
     9301 cgtgcacgag ggctgacgcc cgcccgggca ggagctcgcg tccgaacccc ggcccgccca
     9361 ccgaccgacg agagtgctca gagcgatccg ggagtgatgg tgcccgtcca cacagctgac
     9421 tacgtgatcc agccgcccac cgacgcggcg gaggtacggg gcggccacac gctgcccgag
     9481 gtgttcgaga ccgcgtcgag ggccgccccc gacgcggtgg ccatcgtgga cggggaccgt
     9541 tcgcggacct gggcgcagtg gcgggcggac gtccgcgcgc tggcccgtgg cctccaggaa
     9601 tcgggcgtcg ggcccggtga cgtggtggcg gtgcggctgc cgaacagctg ggagttccag
     9661 accctgcacc tggccgtcgc ggccgtcggc gccgtactgc tgcccgtcca cgagggcacc
     9721 ccgaccgcgg aggtccacgc gctgctgacc cgcgcggaac ccgtactcct cgtcctgtcg
     9781 gcttccggga gcgagggcac ggcaacggcc cgctcgctcc tggagagcgt gccgacgctg
     9841 cgcggcgtgc tgctggccgg ggcgtcggag gcggagtgcg aggagccggg gatcggggcg
     9901 ctggacgggt tgcgggcagc ctggacgggc agcgagcccc ggccggtgca cctcaccccc
     9961 gacatgccgc tcgccctgat cccctcgtcc ggcaccacct cggcgcggcc caagctgtgc
    10021 gtgcacaccc acggcggcct gctggcgaac accgcggccg tcgtggccga tgccgccgac
    10081 gccttcggcg gcacggtcct gaccgcctgc ccgatgaccc acctgttcgg gctccagtcc
    10141 ctgcacacgg cgctgttcgc cgcccggacg caggtcctgc tcaccggctg ggacgtggac
    10201 cgcttcctgg agctggcgcg ggagcacaac ccccgcgtcg tcttcgccgt acccgcccaa
    10261 ctgcgggaca tcgtcgcgcg actcgccagg gcgggcgagc cggcgggctt cgcgccgcac
    10321 caggtgcgta cggcgggcgc cgccctcgca cccgcgctcg ccgcacagat acgcgccgcc
    10381 ctcgactgcg aaccggtcgt ggtgtggggc atgtccgaga tcggcaccgg caccgcaacc
    10441 cgggcccacc accccgacgg cagcgtggga gaaccggtcg acggcgtgcg cgtacgggtc
    10501 gtcgacgagc acggcgcgga gtgcgcggcg ggggagacgg gcgagctcca gtaccagggc
    10561 ccggcgatgt tccgcggcta tttccgcgag ccggagctga cgcgctcggc cctcaccgac
    10621 gacggctggc tgcggaccgg cgacatcgcc gccatcgacg cggacggcgt ggtcgtcctg
    10681 cacggccggg cggccgaagt gatcgccacc ggaggccgga agttcggcgc caccgaaatc
    10741 gagagcctgc tcgcggagct cgcgggcctg ggcccgctgg ccgtggcggg ggcgccggac
    10801 gaccggctcg gcgagtaccc gtgcctggtc gtgaccgacc gcgcggaccg tacgatcggg
    10861 ctgaccgagg tgaccgcgtt cctgcgccgg cggggactcg ccgaccacaa gatccccctc
    10921 gaactggtca ccgtgcgcga gctgcccttc acccccgcgg ggaagctcga ccgcagggca
    10981 ctcaaggagc agctgcgcac cggcctggaa gcgacgcccg tggcggcccg tctcggcgcg
    11041 gtcccgccgg agacggccga agaggcgctg gaactggtac gcgactgcgt cggccaggtc
    11101 ctcggcagca gcggcgaccc ggccggcccc gccgtcggtg cgccggaatt ccccgacacc
    11161 gaattccgcc ggctcggcct cgactccgtc ctcgcggtgc ggctgcgcaa cctgctgcgg
    11221 gaggagaccg ggctgtccct cccggtcacg ctggccttcg acttcccgac gccgcgggcc
    11281 gtggcgcacg cactggccga gcagaacgac ccggcttcgg cggcggcatc ggggaagacg
    11341 gcggaggagg cgcggaggtt cccggccgac gaggccgatc cggtggcgat cgtcgccatg
    11401 gcctgccgcc tgccgggcgg cgccgactct cccgacgccc tgtgggagct gctggccggc
    11461 ggaaccgacg cgatgcggcc cttcccggac gaccgcggct gggacctgga ccgcctcttc
    11521 gacgaggacc ccgaccggcc gggcacctgc tacgcacgcg aaggcggctt cctgcccggc
    11581 gcgggcgact tcgacgcggg cttcttcggc ctgtccgacc acgaggcgac ggccaccgac
    11641 ccgcagcagc gcctgctcct ggtggcggcc tgggagacct tcgagcgggc gggcatcgac
    11701 ccggcgtccc tgaagggcac ccgtacgggc gtgttcaccg gcgcgatgga gcgcggctac
    11761 ggcgctctcg cgtccgccgt ccccagcgag tgggagagca cgctcaccac cggggccgcc
    11821 aacagcgcga tctccgggcg catcgcctac acctacggcc tcgaaggccc cgcgctgacc
    11881 gtcgacaccg cctcctcgtc ctccctcgtc gccctgcacc tggcctgccg ctccctgcgg
    11941 tcgggcgaga ccgacctggc gctggccggc ggcgtcaccg tcatggcgac cccggcgccc
    12001 ttcacccact tcgcccggct gcgcgcgctc gccaccgact cgcgcgccaa ggcgtacgcg
    12061 gacaccgcga acggctccgc gtgggcggaa ggcgcgggac tgctgctgct ggagcggctg
    12121 agcgacgccc gccgcaacgg acaccgtgta ctggcgctcg tacggggctc ggcggtcaac
    12181 caggacggcg cctccaacgg gctcaccgcc ccgagcggcc ccgcgcagca gcgcgtcatc
    12241 cgccaggccc tggccgacgc cggtctgacg ccgcgggacg tggacgcggt ggaggggcac
    12301 ggcaccggca ctccgctcgg cgacccgatc gaggcccagg ccctgatggc cacctacggc
    12361 caggagcggc cggagggacg gccgctgtgg ctggggtcgg tgaagtccaa cctcgggcac
    12421 acacaggccg ctgccggggt cgtcggggtc atcaagacgg tgctcgcgct gggccgcggc
    12481 gtcctgccca ggacgctgca cgtggagact ccttccacca aggtcgactg gtccgccggg
    12541 gcggtacggc tgctgaccga ggcgcagccc tggccccagg agagcgggca cacgcggcgg
    12601 gcaggagtgt cgtccttcgg gctcaccggc accaacgccc acgtgatcct ggaggaggcc
    12661 ccggacggga cgcagagcgc gcccggatcg gaaccggccg acgacaccgc cgtaccgtgg
    12721 gtgctctccg cacggagccg gacggcgctg cgcgaacagg cccgccgcct ggccgagcac
    12781 gtgaccgctc accccggcct gcgcacacag gacatcgccc acgccctggc caccacccgc
    12841 acccggcacc ggcaccgggc cgtcgtcagc ggctccgacc gggaccggat gctgtccgcg
    12901 acggccgcgt tcgggcgcgg ggagcgggcc gcggacgtca ccccgctcga ttccgcgccg
    12961 ggcggcctgg ccttcgtctt ctccggacag ggcggccagc accccggcat ggggcgcggg
    13021 gcggccgagg cgttccccgt gttcggggag gcgctgcgcg aggtgtgcga caccctcgac
    13081 ccgctgctgg cacgtccgct gacctcggtg atgtgggcgg acgccgactc cgaggaggcg
    13141 acgctgctgc acaacgccga gttctcgcag ccctcgctgt tcgccctcca ggtcgccctc
    13201 taccggctgt acgagtcctg gggcatggcc ccggaccgtc tcgcgggcca ttcggccggc
    13261 gagatcgccg ccgcgcatgt caccggcatc ctcaccctcc aggacgcctg cgccctggtg
    13321 gcctcccggg gcaggctgat cagctcgctg ccggtcggcg gcgcgacggt ggcggtgcgc
    13381 atctcggagg acgaggtgcg ggggtggctc gccgaggaga cgaccggctc ggtctcgatc
    13441 gcggccgtca acgggccgca ctccctcgta ctctccggtg ccgaggcccc gctcatcgcc
    13501 ctcacggacc ggctccgcga cgccggccac aagacccacc gcatccccat gagggtcgcg
    13561 gcccactcac cgctgatgga ccccatcctg ggggagttcc gcgcggtcgt ccgcacgctg
    13621 gcctacggca cgcccaccat ccccctcgtc tccaccgtca ccggccgccc gctgaccgac
    13681 gaggaggcgc gcgaccctga gcactgggta cggcacgtgc ggcggcccgt gcgcttcaag
    13741 gacgcgatcg gccggctccg ggaggagcgc gtcaccggct tcctggagct gggcgccgag
    13801 ccgctgctca cccccatgat cgacgagtgc ctggaggcgg ccggcccgca gcacggaacc
    13861 gccgtggtgc cgagcctgag ctccggcgta ccggaccggc agatcctgct ctccgcggcc
    13921 gcccgggtgc acacccacgg cgcacccgtc gactgggacg cggtgctgcc cggggcccgg
    13981 cccgtcgacc tgccgacgta cgcgttccag cggcggcggt tctggctggc ggcggggccg
    14041 ggtgcggccg ccgaggccgg tttcgtgggt gccgcgatcg gcgcgggcgc gccggcggcc
    14101 gatgcggagg agccgtcggg cctggaagcc cggctggccg gtctcgaaga cgccgaacag
    14161 gacgcgtacg tacgctccct ggtgctcgcc gagacctcgg ccgtgctcgg cggccaggaa
    14221 ccgctcgaca gcgaaggcac ccacaccttc aaggagatgg gcatcaactc ggtgaacgcc
    14281 gtcgagctcc gcaaccgcct catcgcggcc acggacctgc ggctccccgc cacgctcgtc
    14341 tacgaccacc ccaccccgaa cgcggtcgtc cgcctcgtac gcgaacgcct cgcgcgcccg
    14401 gccaccgccg cacgcgacgt ggactcggtc gtggccgagc tggagtccct gctcacggcc
    14461 ggcgcggagg tctcggcgga ggcggtggca cggctgaagg cgatggcggc ggggcgggac
    14521 ggcactacgg acaccggttc cggcgggccc ctggacctga cgtcggccag cgacgaggac
    14581 ctgttccggc tgatggacgc ggagcactga gggggcgggt gcgggtgctt tccggagcac
    14641 ccggcgttca tggctgaggg ggccggtccc gcaaggacgc tgttggttta ttcggtccct
    14701 gcttgtgccc cgtcgagcgt catctcggcg gggcacagtg ctgcgaagtg gctggtgcgg
    14761 gtgcgggctc ggggtgtgcc ggtgaggtgg gcgtcgatgc gggcaaggtt gatcgcggct
    14821 ccggtgagct ggtgctggag gctggtcttt gtcaggcccc ggtagcggga tctgcgcagg
    14881 ccgcagcgcc cgactgcttg ggagatgctg ccctcgaccc cggcacggat cttgtaacgg
    14941 tccttccagg catcggtttg ctgctcggcg cggctgtgtc ggatgatctc gtgttcctcc
    15001 cggtgacgca gcatgatctc ccggcgctgg ccggtagccg agcccacgca ctcgtgccgg
    15061 tggggacagg ggcgacactc gctgtggcgg aaccgcacgc ggatgaccgc gaggcccttg
    15121 gagtccgtgc gcggatacca ctgggtcgtg gtgacgccgc cggggcaggc cacctgctgc
    15181 tggtcccagt cgacggtgaa tgcgtccagg ccgtaggggc ccgcggactg ggcggacgtg
    15241 ttggcagcca tgggcccgtg cagcgcgacg ccatgctcgg tgcgggcggc caggacttga
    15301 gtggcggtgg gataaccggc atcgacccag tgttcgccgg gcaggcagtc gcggtcggcg
    15361 aggcccgcgt ggatcgactg gctcatcacg ctgtccgaga cggtggcgac ggtggtggcc
    15421 acgttcgtga tcaggttcgg ggcgtccgcc tcgcagatct cggtgagatg gaccttgtag
    15481 ccgtcccaca tgatgtcccg cttcacgctg ccacgggcct cgcggtcata cggggtgacc
    15541 aggcgcatca tgcccggcgg acggtctttt gggtcccgcc tggccacctc gccctccacc
    15601 atgtggaagt gctggaccca gacctgccgc aggatctcca cctcatcgag tgcgcgaagc
    15661 cggtgcggtg caacggtggc gaagacctcc tccagcagcc gcatcccgtc cctgccgatc
    15721 cgcaggccca cctcgtcccg cctggcacgg cccttgggga accgggactc ctcggcccgg
    15781 gtcgcgtagt gccggaacca gtccggctcg gcggcttcgg ccagccagcc gggggcagcc
    15841 tgggccagtg cgttcagagc cgatcgcagc gtctccgcga ccagctccag ccagttcagc
    15901 tgccgtgccg aggacaagat gtgcgtggag tcggtgcggg cccggcccgc gctcttgagc
    15961 agccccttct cgcgggctgc caccagcaca ccgtccatga cccggcgccc tccatcggcc
    16021 ccggccagcc ggtccctgaa ctccgacagc accgagaagt cgaagccggg atcgcccagt
    16081 tccagcccga gggcgtactt gaagtcgatc cgcgcccgca ccgcttccgc ggcctggcgg
    16141 tcggtcagcc cgtccacgaa ctggagcacc gacaccagcg ccagaccggc cggagaccag
    16201 gcaggccggc ctcgtgaggc gaacagatcc gcgaagtcct cgtcccggaa catcggcccc
    16261 agctcgtccc ggacccggat cgccaggctt cccttcgcaa acgccgcccg ggccacccgc
    16321 accgtctccg ccggaatctc ccccggccca ctcggacgca tcgacatcga cacccacccc
    16381 acacaacaac gtcggtctcc acgaccacaa ccggatcgtg gagaccgacg tcacgcgagg
    16441 gaccgaataa accaacagcg tcccgcaagg gccggccccc tcaggcatgg tgcggatcag
    16501 tcctccagcg tcccgcggaa gcggttgatg gcgctggcgt gccgcgcccg gaactcggcg
    16561 tcccgtacgc cgagtccttc ctcgggagcg agcgccagaa tgccgacctt gccctggtgg
    16621 aggttgcggt gcacgtcgta cgccgcctgc ccggtctccc tcagggggta ggtctgggac
    16681 agcgtcgggt ggatcctgcc cttggcgatc aggcggttgg cctcccacgc ctcgcggtag
    16741 ttggcgaagt gcgagcccac gatgcgcttg agcgacatcc acagatagcg gttgtcgtac
    16801 tggtgctggt agcccgaggt ggaggcgcag gtgacgaccg tgccgccctt gcgcgtgacg
    16861 aacacactcg cgccgaacgt ctcccgcccc gggtgctcga aaacgatgtc cacgtcctcg
    16921 ccgccggtca gctcgcggat gcgcttgccg aaccgcttcc actcccgggg gtcctgcgtc
    16981 tgctcgtcct tccagaaccg gtacccctcg gcgttgcggt cgatgaccgc ttccgcgccc
    17041 atggaccggc agatctccgc cttctggtcg ttggacacca cacagacggg tgtgccgccg
    17101 ccggccagca ccaactgcgt cgcgtacgaa ccgagtccgc cgctcgcgcc ccagatcagc
    17161 acattgtcac cgaccttcat gcccgcgccg ttgcgggaca ccagctggcg gtacgcggtg
    17221 gaattcacca gcccggaggc cgccgcctcc tcccacgtga gatggccggg cttgggcatc
    17281 agctgattcg acttcaccag cgcgagttcg gcgagaccgc cgaaattggt ctcgaagccc
    17341 cagatgcgct gctcggggtc gagcatcgtg tcaccgtggc cgtccgcgct ctccagctcg
    17401 acggacaggc agtgcgcgac gacctcgtca ccgggcttcc agacggtgac gccgggcccg
    17461 gtgcgcagca cgacgcccgc caggtcggag ccgatgacgt ggtacggcag gtcgtgccgc
    17521 ttggcgagct cgctgcgccg gccgtaccgc tccaggaacc cgaacgtcgg cagcggctcg
    17581 aagatcgagg tccagacgct gttgtagttc accgaggacg ccatgacggc caccagggcc
    17641 tcgccgggac cgagttcggg gacggccacc tcgtcgaggt gcagcgactt gcgcgggtcc
    17701 ttgtcgcacc ccgcgagccc ctcgaacatg tcggtctcgt ccttgtggac ggtgatcgcg
    17761 cggtacgact cgggcagcgg cagcgcggcg aagtcggcgg ccgtggtgtc cggcgcctga
    17821 atagcgttca gtatttcctt cacggggagc ctccggaaaa ggcgggtcgg cagtgcagcg
    17881 gtaagggcga ggcgactccg gccgcgtgat caccattccc gtgcgtgagg agtcaacgcc
    17941 tccccgtaat ccccttgggc ggccttggga agaaccccgg aaaacccgcc ccgcgggagc
    18001 acggaaagac gggccaatca tggccggaag gcactagagg aacgcctagt gttcccaccg
    18061 gtaagttcgc ggccgaccgg gcgcgtcctg aatcccgcct tccggaaaac acattcttcc
    18121 gcgcttcttt tcgtccggcc ggatgttctc agagtgcgat gagacccgcg ttcgtcggct
    18181 ggaacccgca ggcgtcgaag tagaacgtgc gcagttcgtc gtcgaagtcg acgtgcagcc
    18241 attcgcaccg cgccgcccgg gcgcccccga cggccgcggc gaccagcccg gcaccgatcc
    18301 cggaacggcg catgtccgcc gtcaccacgg tgtccaggac gaacgcgtgg acaccaccgt
    18361 cccacgcgac attgacgaag ccgacgagtt caccgtcacg gtcgcgccgg gcgcacaccc
    18421 agccgagact gtgccggtgg acctgcgcca cccagtcgat gtccaggccc cggtggccga
    18481 agccctccgc gtgcagccgg ttgacggccg cgttctcgaa gtcgccccgc cactcgtacg
    18541 tgatcgccat gccgtcagcg tagggggcgc gcggttttcc ccgtggcgca caatggtgcg
    18601 catggccgag cttgtcgcaa cgtccgtcgg tggcacaccg atcacggccc tcgacgacgg
    18661 cgaaggaccg ccgctgctcc tcgtgcacgg gggcggtggc ggcaccgcgt cctgggacgg
    18721 cgtcatacgg tcgctggccg acggcttccg ggtggtcagg atcgcccgcc gtatctacgt
    18781 ccccggggcg acgaccccgc cgtactactc gacggccgtc gaagcggcgg acattctggc
    18841 gatcgccggg ctcctcggcc ggcccccgct gctggccggt cactcctcgg gcgcggtcgc
    18901 cgcgctcgaa gcggcggtgc gtgcgcccga ggcactggcg ggcctgttcc tctacgaacc
    18961 gccggtgtcc acccggtccc tggccggagg ggaggcggcc cggcgcgccc gtgcggcgtt
    19021 cgaggcggga gacgcccgcg aggcgatgcg gatcc
//
