BGC0000140: 4-hexadecanoyl-3-hydroxy-2-(hydroxymethyl)-2H-furan-5-one biosynthetic gene cluster from Streptomyces sp. 88-682
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Location: 1 - 15,000 nt. (total: 15,000 nt).
This entry is originally from NCBI GenBank GQ332353.1.

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core biosynthetic genes
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Gene details
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NRPS/PKS domains
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General information about the BGC
MIBiG accession BGC0000140
Short description 4-hexadecanoyl-3-hydroxy-2-(hydroxymethyl)-2H-furan-5-one biosynthetic gene cluster from Streptomyces sp. 88-682
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide
Loci NCBI GenBank: GQ332353.1
Compounds
  • 4-hexadecanoyl-3-hydroxy-2-(hydroxymethyl)-2H-furan-5-one
Species Streptomyces sp. 88-682 [taxonomy]
References
Chemical products information
4-hexadecanoyl-3-hydroxy-2-(hydroxymethyl)-2H-furan-5-one
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C21H36O5
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ACZ65471.1
 113 - 1258 (-) putative dipeptidyl aminopeptidase
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  • ACZ65472.1
  • rkI
 1382 - 2071 (-) TetR transcriptional regulator
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  • ACZ65473.1
  • rkH
 2074 - 3669 (-) antibiotic efflux protein
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  • ACZ65474.1
  • rkA
 4025 - 5821 (+) palmitoyl-CoA synthetase
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  • ACZ65475.1
  • rkB
 5864 - 6178 (+) acyl carrier protein
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  • ACZ65476.1
  • rkC
 6175 - 9195 (+) type I modular polyketide synthase
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  • ACZ65477.1
  • rkD
 9192 - 10223 (+) 3-oxoacyl-(acyl carrier protein) synthase III
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  • ACZ65478.1
  • rkE
 10220 - 12145 (+) FkbH-like glyceryl-S-ACP synthase
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  • ACZ65479.1
  • rkF
 12148 - 12387 (+) acyl carrier protein
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  • ACZ65480.1
  • rkG
 12384 - 13187 (+) type II thioesterase
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  • ACZ65481.1
 13197 - 14048 (-) putative beta-lactamase domain-containing protein
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Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
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