BGC0000140: 4-hexadecanoyl-3-hydroxy-2-(hydroxymethyl)-2H-furan-5-one biosynthetic gene cluster from Streptomyces sp. 88-682
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Location: 1 - 15,000 nt. (total: 15,000 nt).
This entry is originally from NCBI GenBank GQ332353.1.

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core biosynthetic genes
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Gene details
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General
Compounds
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Biosynthesis
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NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000140
Short description 4-hexadecanoyl-3-hydroxy-2-(hydroxymethyl)-2H-furan-5-one biosynthetic gene cluster from Streptomyces sp. 88-682
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
GQ332353.1
via
Compounds
  • 4-hexadecanoyl-3-hydroxy-2-(hydroxymethyl)-2H-furan-5-one
Species Streptomyces sp. 88-682 [taxonomy]
References
Chemical products information
4-hexadecanoyl-3-hydroxy-2-(hydroxymethyl)-2H-furan-5-one Evidence:
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C21H36O5
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ACZ65471.1
 113 - 1258 (-) putative dipeptidyl aminopeptidase
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    • ACZ65472.1
    • rkI
    		 1382 - 2071 (-) TetR transcriptional regulator
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      • ACZ65473.1
      • rkH
      		 2074 - 3669 (-) antibiotic efflux protein
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        • ACZ65474.1
        • rkA
        		 4025 - 5821 (+) palmitoyl-CoA synthetase
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          • ACZ65475.1
          • rkB
          		 5864 - 6178 (+) acyl carrier protein
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            • ACZ65476.1
            • rkC
            		 6175 - 9195 (+) type I modular polyketide synthase
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              • ACZ65477.1
              • rkD
              		 9192 - 10223 (+) 3-oxoacyl-(acyl carrier protein) synthase III
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                • ACZ65478.1
                • rkE
                		 10220 - 12145 (+) FkbH-like glyceryl-S-ACP synthase
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                  • ACZ65479.1
                  • rkF
                  		 12148 - 12387 (+) acyl carrier protein
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                    • ACZ65480.1
                    • rkG
                    		 12384 - 13187 (+) type II thioesterase
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                      • ACZ65481.1
                      		 13197 - 14048 (-) putative beta-lactamase domain-containing protein
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                        Biosynthesis information
                        Annotation changelog

                        Entry version: 4

                        Date
                        Changes
                        Submitters
                        Reviewers
                        2022-10-07
                        Update chemical activity to schema version 2.11
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                        Entry version: 3

                        Date
                        Changes
                        Submitters
                        Reviewers
                        2022-09-15
                        Updated bioactivity data
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                        Entry version: 2

                        Date
                        Changes
                        Submitters
                        Reviewers
                        2019-10-16
                        Migrated from v1.4
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        2019-10-16
                        Updated compound(s) information (NPAtlas curation)
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                        Entry version: 1

                        Date
                        Changes
                        Submitters
                        Reviewers
                        2015-06-12
                        Submitted
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                        Detailed domain annotation
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