LOCUS       BGC0000148             80161 bp    DNA     linear   BCT 16-MAY-2001
DEFINITION  Saccharopolyspora spinosa probable lysR-type transcriptional
            regulator, probable keto acyl reductase, spinosad biosynthetic gene
            cluster, complete sequence, and probable exodeoxyribonuclease V
            genes, complete cds; and unknown gene.
ACCESSION   BGC0000148
VERSION     BGC0000148
KEYWORDS    .
SOURCE      Saccharopolyspora spinosa
  ORGANISM  Saccharopolyspora spinosa
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Saccharopolyspora.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 13:00:23
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..80161
                     /db_xref="taxon:60894"
                     /mol_type="genomic DNA"
                     /organism="Saccharopolyspora spinosa"
     subregion       1..80161
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0000148"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..80161
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /subregion_numbers="1"
                     /tool="antismash"
     protocluster    1111..80161
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[21110:76569]"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      21111..76569
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     cand_cluster    1111..80161
                     /SMILES="C(C)C(=O)CC(O)CCC(C)C(O)CC(O)C=CCC(O)CC(O)C(C)=CC=
                     CC=CC(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     CDS             complement(1135..1971)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014:LysR family
                     transcriptional regulator (Score: 160.1; E-value: 1.1e-48)"
                     /gene_kind="regulatory"
                     /note="ORF L16"
                     /product="probable lysR-type transcriptional regulator"
                     /protein_id="AAG23282.1"
                     /transl_table=11
                     /translation="METRELRYFVAVAEELHFGRAAQRLGIAQPPLSRTIAQLEQRLGV
                     VLLQRTSRKVSLTEAGAMLLTEGRAILGALAAAERRTQRAATSQPSLVLAAKAGASGEL
                     LAKLLDAYAAEPGAVAVDLLLCESQPQKTLHDGRADVALLHQPFDPTAELDIEILNTEQ
                     QVAILPTSHPLASEPHVRMADVSSLPDLPLARWPGPDGVYPDGPGVEVRNQTQLFQMIA
                     LGRTTVVMPESSRVNLLEGLAAVPVLDAPDVTTVIAWPPHSRSRALAGLVRVATLL"
     CDS             2024..2791
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     185; E-value: 2.8e-56)"
                     /gene_kind="biosynthetic-additional"
                     /note="ORF L15"
                     /product="probable keto acyl reductase"
                     /protein_id="AAG23281.1"
                     /transl_table=11
                     /translation="MVLVPRRFRATLESMSEQTIALVTGANKGIGYEIAAGLGALGWSV
                     GIGARDHQRGEDAVAKLRADGVDAFAVSLDVTDDASVAAAAALLEERAGRLDVLVNNAG
                     IAGAWPEEPSTVTPASLRAVVETNVIGVVRVTNAMLPLLRRSERPRIVNQSSHVASLTL
                     QTTPGVDLGGISGAYSPSKTFLNAITIQYAKELSDTNIKINNACPGYVATDLNGFHGTS
                     TPADGARIAIRLATLPDDGPTGGMFDDAGNVPW"
     gene            complement(3416..4165)
                     /gene="spnS"
     CDS             complement(3416..4165)
                     /codon_start=1
                     /gene="spnS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1248:methyltransferase (Score: 202.6; E-value:
                     1.2e-61)"
                     /gene_kind="biosynthetic-additional"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="probably involved in forosamine biosynthesis"
                     /product="probable N-dimethyltransferase"
                     /protein_id="AAG23280.1"
                     /transl_table=11
                     /translation="MSRVSDTFAETSSVYSPDHADIYDAIHSARGRDWAAEAGEVVQLV
                     RTRLPEAQSLLDVACGTGAHLERFRAEYAKVAGLELSDAMREIAIRRVPEVPIHIGDIR
                     DFDLGEPFDVITCLCFTAAYMRTVDDLRRVTRNMARHLAPGGVAVIEPWWFPDKFIDGF
                     VTGAVAHHGERVISRLSHSVLEGRTSRMTVRYTVAEPTGIRDFTEFEILSLFTEDEYTA
                     ALEDAGIRAEYLPGAPNGRGLFVGIRN"
     gene            complement(4168..5325)
                     /gene="spnR"
     CDS             complement(4168..5325)
                     /NRPS_PKS="Domain: Aminotran_1_2 (33-155). E-value:
                     7.2e-10. Score: 30.3. Matches aSDomain:
                     nrpspksdomains_spnR_Aminotran_1_2.1"
                     /codon_start=1
                     /gene="spnR"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056:DegT/DnrJ/EryC1/StrS aminotransferase (Score:
                     360; E-value: 2.5e-109)"
                     /gene_kind="biosynthetic-additional"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="probably involved in forosamine biosynthesis"
                     /product="probable aminotransferase"
                     /protein_id="AAG23279.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 2e-97, bitscore:
                     317.2, seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_1_2 (E-value: 3e-10, bitscore:
                     30.3, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_5 (E-value: 6.3e-10, bitscore:
                     29.0, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINLHQPILGTEELDAIAEVFASNWIGLGPRTRTFEAEFAHHLGV
                     DPEQVVFLNSGTAALFLTVQVLDLGPGDDVVLPSISFVAAANAIASSGARPVFCDVDPR
                     TLNPTLDDVARAITPATKAVLLLHYGGSPGEVTAIADFCREKGLMLIEDSACAVASSVH
                     GTACGTFGDLATWSFDAMKILVTGDGGMFYAADPELAHRARRLAYHGLEQMSGFDSAKS
                     SNRWWDIRVEDIGQRLIGNDMTAALGSVQLRKLPEFINRRREIATQYDRLLSDVPGVLL
                     PPTLPDGHVSSHYFYWVQLAPEIRDQVAQQMLERGIYTSYRYPPLHKVPIYRADCKLPS
                     AEDACRRTLLLPLHPSLDDAEVRTVADEFQKAVEHHISQRSPLRK"
     aSDomain        complement(4861..5226)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spnR_Aminotran_1_2.1"
                     /evalue="7.20E-10"
                     /label="spnR_Aminotran_1_2.1"
                     /locus_tag="spnR"
                     /protein_end="155"
                     /protein_start="33"
                     /score="30.3"
                     /tool="antismash"
                     /translation="TFEAEFAHHLGVDPEQVVFLNSGTAALFLTVQVLDLGPGDDVVLP
                     SISFVAAANAIASSGARPVFCDVDPRTLNPTLDDVARAITPATKAVLLLHYGGSPGEVT
                     AIADFCREKGLMLIEDSA"
     gene            complement(5363..6751)
                     /gene="spnQ"
     CDS             complement(5363..6751)
                     /NRPS_PKS="Domain: Beta_elim_lyase (88-218). E-value:
                     3.3e-07. Score: 21.7. Matches aSDomain:
                     nrpspksdomains_spnQ_Beta_elim_lyase.1"
                     /codon_start=1
                     /gene="spnQ"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056:DegT/DnrJ/EryC1/StrS aminotransferase (Score:
                     369.2; E-value: 4e-112)"
                     /gene_kind="biosynthetic-additional"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="probably involved in forosamine biosynthesis"
                     /product="probable NDP-hexose-3,4-dehydratase"
                     /protein_id="AAG23278.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 2.3e-103,
                     bitscore: 336.7, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQSRKTRALGKGRARVTSCDDTCATATEMVPDAKDRILASVRDYH
                     REQESPTFVAGSTPIRPSGAVLDEDDRVALVEAALELRIAAGGNARRFESEFARFFGLR
                     KAHLVNSGSSANLLALSSLTSPKLGEARLRPGDEVITAAVGFPTTINPAVQNGLVPVFV
                     DVELGTYNATPDRIKAAVTERTRAIMLAHTLGNPFAADEIAEIAKEHELFLVEDNCDAV
                     GSTYRGRLTGTFGDLTTVSFYPAHHITSGEGGCVLTGSLELARIIESLRDWGRDCWCEP
                     GVDNTCRKRFDYHLGTLPPGYDHKYTFSHVGYNLKTTDLQAALALSQLSKISAFGSARR
                     RNWRRLREGLSGLPGLLLPVATPHSDPSWFGFAITISADAGFTRAALVNFLESRNIGTR
                     LLFGGNITRHPAFEQVRYRIADALTNSDIVTDRTFWVGVYPGITDQMIDYVVESIAEFV
                     AKSS"
     aSDomain        complement(6098..6487)
                     /aSDomain="Beta_elim_lyase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spnQ_Beta_elim_lyase.1"
                     /evalue="3.30E-07"
                     /label="spnQ_Beta_elim_lyase.1"
                     /locus_tag="spnQ"
                     /protein_end="218"
                     /protein_start="88"
                     /score="21.7"
                     /tool="antismash"
                     /translation="NARRFESEFARFFGLRKAHLVNSGSSANLLALSSLTSPKLGEARL
                     RPGDEVITAAVGFPTTINPAVQNGLVPVFVDVELGTYNATPDRIKAAVTERTRAIMLAH
                     TLGNPFAADEIAEIAKEHELFLVEDN"
     gene            7083..8450
                     /gene="spnP"
     CDS             7083..8450
                     /codon_start=1
                     /gene="spnP"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MGT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1062:glycosyltransferase, MGT family (Score: 375.1;
                     E-value: 8.1e-114)"
                     /gene_kind="biosynthetic-additional"
                     /note="involved in forosamine addition"
                     /product="probable NDP-forosamyltransferase"
                     /protein_id="AAG23277.1"
                     /sec_met_domain="MGT (E-value: 5e-139, bitscore: 454.3,
                     seeds: 193, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MILGMLPGCSIAIGEFMRVLFTPLPASSHFFNLVPLAWALRAAGH
                     EVRVAICPNMVSMVTGAGLTAVPVGDELDLISLAAKNELVLGSGVSFDEKGRHPELFDE
                     LLSINSGRDTDAVEQLHLVDDRSLDDLMGFAEKWQPDLVVWDAMVCSGPVVARALGARH
                     VRMLVALDVSGWLRSGFLEYQESKPPEQRVDPLGTWLGAKLAKFGATFDEEIVTGQATI
                     DPIPSWMRLPVDLDYISMRFVPYNGPAVLPEWLRERPTKPRVCITRGLTKRRLSRVTEQ
                     YGEQSDQEQAMVERLLRGAARLDVEVIATLSDDEVREMGELPSNVRVHEYVPLNELLES
                     CSVIIHHGSTTTQETATVNGVPQLILPGTFWDESRRAELLADRGAGLVLDPATFTEDDV
                     RGQLARLLDEPSFAANAALIRREIEESPSPHDIVPRLEKLVAERENRRTGQSDGHP"
     gene            8967..10427
                     /gene="spnO"
     CDS             8967..10427
                     /codon_start=1
                     /gene="spnO"
                     /note="involved in forosamine biosynthesis"
                     /product="probable NDP-hexose-2,3-dehydratase"
                     /protein_id="AAG23276.1"
                     /transl_table=11
                     /translation="MSSSVEAEASAAAPLGSNNTRRFVDSALSACNGMIPTTEFHCWLA
                     DRLGENSFETNRIPFDRLSKWKFDASTENLVHADGRFFTVEGLQVETNYGAAPSWHQPI
                     INQAEVGILGILVKEIDGVLHCLMSAKMEPGNVNVLQLSPTVQATRSNYTQAHRGSVPP
                     YVDYFLGRGRGRVLVDVLQSEQGSWFYRKRNRNMVVEVQEEVPVLPDFCWLTLGQVLAL
                     LRQDNIVNMDTRTVLSCIPFHDSATGPELAASEEPFRQAVARSLSHGIDSSSISEAVGW
                     FEEAKARYRLRATRVPLSRVDKWYRTDTEIAHQDGKYFAVIAVSVSATNREVASWTQPM
                     IEPREQGEIALLVKRIGGVLHGLVHARVEAGYKWTAEIAPTVQCSVANYQSTPSNDWPP
                     FLDDVLTADPETVRYESILSEEGGRFYQAQNRYRIIEVHEDFAARPPSDFRWMTLGQLG
                     ELLRSTHFLNIQARSLVASLHSLWALGR"
     gene            10436..11434
                     /gene="spnN"
     CDS             10436..11434
                     /codon_start=1
                     /gene="spnN"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079:oxidoreductase (Score: 257.3; E-value: 4.1e-78)"
                     /gene_kind="biosynthetic-additional"
                     /note="involved in forosamine biosynthesis"
                     /product="probable NDP-hexose-3-ketoreductase"
                     /protein_id="AAG23275.1"
                     /transl_table=11
                     /translation="MRKPVRIGVLGCASFAWRRMLPAMCDVAETEVVAVASRDPAKAER
                     FAARFECEAVLGYQRLLERPDIDAVYVPLPPGMHAEWIGKALEADKHVLAEKPLTTTAS
                     DTARLVGLARRKNLLLRENYLFLHHGRHDVVRDLLQSGEIGELREFTAVFGIPPLPDTD
                     IRYRTELGGGALLDIGVYPARAARHFLLGPLTVLGASSHEAQESGVDLSGSVLLQSEGG
                     TVAHLGYGFVHHYRSAYELWGSRGRIVVDRAFTPPAEWQAVIRIERKGVVDELSLPAED
                     QVRKAVTAFARDIRAGTGVDDPAVAGDSGESMIQQAALVEAIGQARRCGST"
     gene            complement(11530..12492)
                     /gene="spnM"
     CDS             complement(11530..12492)
                     /codon_start=1
                     /gene="spnM"
                     /note="involved in spinosyn aglycone biosynthesis"
                     /product="SpnM"
                     /protein_id="AAG23274.1"
                     /transl_table=11
                     /translation="MPNAVSGTVLVPNIPWPREDRPIITFAVGTHGLGSQVAPSYLLRT
                     GTEPETELIAVALDRGWAVVITDYEGLGTPGTHTYTVGRAQGHAMLDAARAAQRLPGSG
                     LTTDCPVGIWGYAQGGQASAFAGELHPTYAPELRIRAAAAGAVPIDLLDIIHRNDGVFT
                     GPVLAGLVGHAAAYPDLPFDELLTEAGRTAVDQVRELGAPELVTRFLGRELSDFLDTSG
                     LFEQPRWRARLAESVAGRNGGPVVPTLVYHSTDDEIVPFAFGERLRDSYRAAGTPVRWH
                     PLSGLAHFPAALASSRVVVSWFDEHFSEPSAISGPRDAR"
     gene            complement(12696..13547)
                     /gene="spnL"
     CDS             complement(12696..13547)
                     /NRPS_PKS="Domain: oMT (33-169). E-value: 1.2e-12. Score:
                     38.4. Matches aSDomain: nrpspksdomains_spnL_oMT.1"
                     /codon_start=1
                     /gene="spnL"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 146.6; E-value:
                     1.5e-44)"
                     /gene_kind="biosynthetic-additional"
                     /note="involved in spinosyn aglycone biosynthesis; possibly
                     involved in polyketide bridging"
                     /product="methyltransferase-like protein"
                     /protein_id="AAG23273.1"
                     /transl_table=11
                     /translation="MESIFDALAHGRPLHHGYWAGGYREDAGATPWSDAADQLTDLFID
                     KAALRPGAHLFDLGCGNGQPVVRAACASGVRVTGITVNAQHLAAATRLANETGLAGSLE
                     FDLVDGAQLPYPDGFFQAAWAMQSVVQIVDQAAAIREVHRILEPGGRFVLGDIITRVRL
                     PEEYAAVWTGTTAHTLNSFTALVSEAGFEILEVTDLTAQTRCMVSWYVDELLRKLDELA
                     GVEPAAVGTYQQRYLGDIAAKHGPGPAQLIAAVAEYRKHPDYARNEESMGFMLLQARKK
                     QS"
     aSDomain        complement(13041..13448)
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spnL_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="1.20E-12"
                     /label="spnL_oMT.1"
                     /locus_tag="spnL"
                     /protein_end="169"
                     /protein_start="33"
                     /score="38.4"
                     /tool="antismash"
                     /translation="DAADQLTDLFIDKAALRPGAHLFDLGCGNGQPVVRAACASGVRVT
                     GITVNAQHLAAATRLANETGLAGSLEFDLVDGAQLPYPDGFFQAAWAMQSVVQIVDQAA
                     AIREVHRILEPGGRFVLGDIITRVRLPEEYAA"
     gene            complement(13592..14785)
                     /gene="spnK"
     CDS             complement(13592..14785)
                     /codon_start=1
                     /gene="spnK"
                     /note="probably involved in rhamnose O-methylation"
                     /product="probable O-methyltransferase"
                     /protein_id="AAG23272.1"
                     /transl_table=11
                     /translation="MSTTHEIETVERIILAAGSSAASLADLTTELGLARIAPVLIDEIL
                     FRAEPAPDIERTEVAVQITHRGETVDFVLTLQSGELIKAEQRPVGDVPLRIGYELTDLI
                     AELFGPGAPRAVGARSTNFLRTTTSGSIPGPSELSDGFQAISAVVAGCGHRRPDLNLLA
                     SHYRTDKWGGLHWFTPLYERHLGEFRDRPVRILEIGVGGYNFDGGGGESLKMWKRYFHR
                     GLVFGMDVFDKSFLDQQRLCTVRADQSKPEELAAVDDKYGPFDIIIDDGSHINGHVRTS
                     LETLFPRLRSGGVYVIEDLWTTYAPGFGGQAQCPAAPGTTVSLLKNLLEGVQHEEQPHA
                     GSYEPSYLERNLVGLHTYHNIAFLEKGVNAEGGVPAWVPRSLDDILHLADVNSAEDE"
     gene            complement(14799..16418)
                     /gene="spnJ"
     CDS             complement(14799..16418)
                     /codon_start=1
                     /gene="spnJ"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1138:FAD linked oxidase domain protein (Score: 478.2;
                     E-value: 6.7e-145)"
                     /gene_kind="biosynthetic-additional"
                     /note="involved in spinosyn aglycone biosynthesis; possibly
                     involved in polyketide bridging"
                     /product="putative oxidoreductase"
                     /protein_id="AAG23271.1"
                     /transl_table=11
                     /translation="MISAAGEQSGPVRKGGAVPEFHDPAPMNRRTPGTEITVEPDDPRY
                     PDLVVGHNPRFTGKPERIHIASSAEDVVHAVADAVRTGRRVGVRSGGHCFENLVADPAI
                     RVLVDLSELNRVYYDSTRGAFAIEAGAALGQVYRTLFKNWGVTIPTGACPGVGAGGHIL
                     GGGYGPLSRRFGSVVDYLQGVEVVVVDQAGEVHIVEADRNSTGAGHDLWWAHTGGGGGN
                     FGIVTRFWLRTPDVVSTDAAELLPRPPATVLLRSFHWPWHELTEQSFAVLLQNFGNWYE
                     QHSAPESTQLGLFSTLVCAHRQAGYVTLNVHLDGTDPNAERTLAEHLSAINAQVGVTPA
                     EGLRETLPWLRSTQVAGAIAEGGEPGMQRTKVKAAYLRTGLSEAQLATVYRRLTVYGYD
                     NPAAALLLLGYGGMANAVAPSATALAQRDSVLKALFVTNWSEPAEDERHLTWIRGFYRE
                     MYAETGGVPVPGTRVDGSYINYPDTDLADPLWNTSGVAWHDLYYKDNYPRLQRAKARWD
                     PQNIFQHGLSIKPPARLSPGQP"
     gene            16556..17743
                     /gene="spnI"
     CDS             16556..17743
                     /codon_start=1
                     /gene="spnI"
                     /note="involved in rhamnose O-methylation"
                     /product="probable O-methyltransferase"
                     /protein_id="AAG23270.1"
                     /transl_table=11
                     /translation="MSEIAVAPWSVVERLLLAAGAGPAKLQEAVQVAGLDAVADAIVDE
                     LVVRCDPLSLDESVRIGLEITSGAQLVRRTVELDHAGLRLAAVAEAAAVLRFDAVDLLE
                     GLFGPVDGRRHNSREVRWSDSMTQFSPDQGLAGAQRLLAFRNRVSTAVHAVLAAAATRR
                     ADLGALAVRYGSDKWADLHWYTEHYEHHFSRFQDAPVRVLEIGIGGYHAPELGGASLRM
                     WQRYFRRGLVYGLDIFEKAGNEGHRVRKLRGDQSDAEFLEDMVAKIGPFDIVIDDGSHV
                     NDHVKKSFQSLFPHVRPGGLYVIEDLQTAYWPGYGGRDGEPAAQRTSIDMLKELIDGLH
                     YQERESRCGTEPSYTERNVAALHFYHNLVFVEKGLNAETAAPGFVPRQALGVEGG"
     gene            complement(17749..18501)
                     /gene="spnH"
     CDS             complement(17749..18501)
                     /codon_start=1
                     /gene="spnH"
                     /note="involved in rhamnose O-methylation"
                     /product="probable O-methyltransferase"
                     /protein_id="AAG23269.1"
                     /transl_table=11
                     /translation="MPSQNALYLDLLKKVLTNTIYSDRPHPNAWQDNTDYRQAARAKGT
                     DWPTVAHTMIGLERLDNLQHCVEAVLADGVPGDFAETGVWRGGACIFMRAVLQAFGDTG
                     RTVWVVDSFQGMPESSAQDHQADQAMALHEYNDVLGVSLETVRQNFARYGLLDEQVRFL
                     PGWFRDTLPTAPIQELAVLRLDGDLYESTMDSLRNLYPKLSPGGFVIIDDYFLPSCQDA
                     VKGFRAELGITEPIHDIDGTGAYWRRSW"
     gene            complement(18541..19713)
                     /gene="spnG"
     CDS             complement(18541..19713)
                     /codon_start=1
                     /gene="spnG"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MGT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1062:glycosyltransferase, MGT family (Score: 282.8;
                     E-value: 8.9e-86)"
                     /gene_kind="biosynthetic-additional"
                     /note="involved in rhamnose addition"
                     /product="probable NDP-rhamnosyltransferase"
                     /protein_id="AAG23268.1"
                     /sec_met_domain="MGT (E-value: 3.1e-109, bitscore: 356.3,
                     seeds: 193, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVLVVPLPYPTHLMAMVPLCWALQASGHEVLIAAPPELQATAHG
                     AGLTTAGIRGNDRTGDTGGTTQLRFPNPAFGQRDTEAGRQLWEQTASNVAQSSLDQLPE
                     YLRLAEAWRPSVLLVDVCALIGRVLGGLLDLPVVLHRWGVDPTAGPFSDRAHELLDPVC
                     RHHGLTGLPTPELILDPCPPSLQASDAPQGAPVQYVPYNGSGAFPAWGAARTSARRVCI
                     CMGRMVLNATGPAPLLRAVAAATELPGVEAVIAVPPEHRALLTDLPDNARIAESVPLNL
                     FLRTCELVICAGGSGTAFTATRLGIPQLVLPQYFDQFDYARNLAAAGAGICLPDEQAQS
                     DHEQFTDSIATVLGDTGFASAAIKLSDEITAMPHPAALVRTLENTAAIRA"
     gene            20168..20995
                     /gene="spnF"
     CDS             20168..20995
                     /NRPS_PKS="Domain: oMT (32-166). E-value: 5.3e-29. Score:
                     92.4. Matches aSDomain: nrpspksdomains_spnF_oMT.1"
                     /codon_start=1
                     /gene="spnF"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 184.9; E-value: 3e-56)"
                     /gene_kind="biosynthetic-additional"
                     /note="possibly involved in polyketide bridging; involved
                     in spinosyn aglycone biosynthesis"
                     /product="methyltransferase-like protein"
                     /protein_id="AAG23267.1"
                     /transl_table=11
                     /translation="MLPGGAPTSQQVGQMYDLVTPLLNSVAGGPCAIHHGYWENDGRAS
                     WQQAADRLTDLVAERTVLDGGVRLLDVGCGTGQPALRVARDNAIQITGITVSQVQVAIA
                     ADCARERGLSHRVDFSCVDAMSLPYPDNAFDAAWAMQSLLEMSEPDRAIREILRVLKPG
                     GILGVTEVVKREAGGGMPVSGDRWPTGLRICLAEQLLESLRAAGFEILDWEDVSSRTRY
                     FMPQFAEELAAHQHGIADRYGPAVAGWAAAVCDYEKYAHDMGYAILTARKPVG"
     aSDomain        20264..20665
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spnF_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="5.30E-29"
                     /label="spnF_oMT.1"
                     /locus_tag="spnF"
                     /protein_end="166"
                     /protein_start="32"
                     /score="92.4"
                     /tool="antismash"
                     /translation="IHHGYWENDGRASWQQAADRLTDLVAERTVLDGGVRLLDVGCGTG
                     QPALRVARDNAIQITGITVSQVQVAIAADCARERGLSHRVDFSCVDAMSLPYPDNAFDA
                     AWAMQSLLEMSEPDRAIREILRVLKPGGIL"
     gene            21111..28898
                     /gene="spnA"
     CDS             21111..28898
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (7-424). E-value:
                     1.7e-164. Score: 539.6. Matches aSDomain:
                     nrpspksdomains_spnA_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (528-824). E-value: 4.7e-111.
                     Score: 362.7. Matches aSDomain:
                     nrpspksdomains_spnA_PKS_AT.1"
                     /NRPS_PKS="Domain: ACP (908-978). E-value: 1.3e-27. Score:
                     87.8. Matches aSDomain: nrpspksdomains_spnA_ACP.1"
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (999-1416). E-value:
                     2.8e-182. Score: 598.2. Matches aSDomain:
                     nrpspksdomains_spnA_PKS_KS.2"
                     /NRPS_PKS="Domain: PKS_AT (1525-1826). E-value: 5.3e-103.
                     Score: 336.3. Matches aSDomain:
                     nrpspksdomains_spnA_PKS_AT.2"
                     /NRPS_PKS="Domain: PKS_KR (2159-2337). E-value: 7.2e-60.
                     Score: 193.9. Matches aSDomain:
                     nrpspksdomains_spnA_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (2431-2517). E-value: 1.1e-26.
                     Score: 84.8. Matches aSDomain:
                     nrpspksdomains_spnA_PKS_PP.1"
                     /NRPS_PKS="Domain: PKS_Docking_Cterm (2528-2592). E-value:
                     3.6e-09. Score: 29.3. Matches aSDomain:
                     nrpspksdomains_spnA_PKS_Docking_Cterm.1"
                     /codon_start=1
                     /gene="spnA"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     mod_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     hyb_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 303.2; E-value:
                     5.3e-92)"
                     /gene_kind="biosynthetic"
                     /note="involved in spinosyn aglycone biosynthesis"
                     /product="polyketide synthase loading and extender module
                     1"
                     /protein_id="AAG23264.1"
                     /sec_met_domain="hyb_KS (E-value: 2.8e-168, bitscore:
                     550.7, seeds: 33, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 1.9e-111, bitscore:
                     362.7, seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.7e-15, bitscore:
                     48.0, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="mod_KS (E-value: 8.1e-225, bitscore:
                     737.0, seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 1.2e-59, bitscore:
                     191.8, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEAGNLIAVIGLSCRLPQAPDPASFWRLLRTGTDAITTVPEGRW
                     GDPLPGRDAPKGPEWGGFLADVDCFDPEFFGISPREAATVDPQQRLALELAWEALEDAG
                     IPAGELRGTAAGVFMGAISDDYAALLRESPPEVAAQYRLTGTHRSLIANRVSYVLGLRG
                     PSLTVDSGQSSSLVGVHLASESLRRGECTIALAGGVNLNLAAESNSALMDFGALSPDGR
                     CFTFDVRANGYVRGEGGGLVVLKKADQAHADGDRIYCLIRGSAVNNDGGGAGLTVPAAD
                     AQAELLRQAYRNAGVDPAAVQYVELHGSATRVGDPVEAAALGAVLGAARRPGDELRVGS
                     AKTNVGHLEAAAGVTGLLKTALSIWHRELPPSLHFTAPNPEIPLDELNLRVQRDLRPWP
                     ESEGPLLAGVSAFGMGGTNCHLVLSGTSRVERRRSGPAEATMPWVLSARTPVALRAQAA
                     RLHTHLNTAGQSPLDVAYSLATTRSALPHRAALVADDEPKLLAGLKALADGDDAPTLCH
                     GATSGERAAVFVFPGQGSQWIGMGRQLLETSEVFAASMSDCADALAPHLDWSLLDVLRN
                     AAGAAHLDHDDVVQPALFAIMVSLAELWRSWGVRPVAVVGHSQGEIAAACVAGALSVRD
                     AARVVAVRSRLLTALAGSGAMASLQHPAEEVRQILLPWRDRIGVAGVNGPSSTLVSGDR
                     EAMAELLAECADRELRMRRIPVEYASHSPHIEVVRDELLGLLAPVEPRTGSIPIYSTTT
                     GDLLDRPMDADYWYRNLRQPVLFEAAVEALLKRGYDAFIEISPHPVLTANIQETAVRAG
                     REVVALGTLRRGEGGMRQALTSLARAHVHGVAADWHAVFAGTGAQRVDLPTYAFQRQRY
                     WLDAKLPDVAMPESDVSTALREKLRSSPRADVDSTTLTMIRAQAAVVLGHSDPKEVDPD
                     RTFKDLGFDSSMVVELCDRLNAATGLRLAPSVVFDCPTPDKLARQVRTLLLGEPAPMTS
                     HRPDSDADEPIAVIGMGCRFPGGVSSPEELWQLVAAGRDVVSEFPADRGWDLERAGTSH
                     VRAGGFLHGAPDFDPGFFRISPREALAMDPQQRLLLEIAWEAVERGGINPQHLHGSQTG
                     VFVGATSLDYGPRLHEASEEAAGYVLTGSTTSVASGRVAYSFGFEGPAVTVDTACSSSL
                     VALHLACQSLRSGECDLALAGGVTVMATPGMFVEFSRQRGLAPDGRCKSFAEAADGTGW
                     SEGAGLVLLERLSDARRNGHEVLAVVRGSAVNQDGASNGLTAPNGSSQQRVIAQALASA
                     GLSVSDVDAVEAHGTGTRLGDPIEAQALIATYGQGRLPERPLWLGSMKSNIGHAQAAAG
                     IAGVMKMVMAMRHGQLPRTLHVDEPTSGVDWSAGTVQLLTENTPWPGSGRVRRVGVSSF
                     GISGTNAHVILEQPPGVPSQSAGPGSGSVVDVPVVPWMVSGKTPEALSAQATALMTYLD
                     ERPDVSSLDVGYSLALTRSALDERAVVLGSDRETLLCGVKALSAGHEASGLVTGSVGAG
                     GRIGFVFSGQGGQWLGMGRGLYRAFPVFAAAFDEACAELDAHLGQEIGVREVVSGSDAQ
                     LLDRTLWAQSGLFALQVGLLKLLDSWGVRPSVVLGHSVGELAAAFAAGVVSLSGAARLV
                     AGRARLMQALPSGGGMLAVPAGEELLWSLLADQGDRVGIAAVNAAGSVVLSGDRDVLDD
                     LAGRLDGQGIRSRWLRVSHAFHSYRMDPMLAEFAELARTVDYRRCEVPIVSTLTGDLDD
                     AGRMSGPDYWVRQVREPVRFADGVQALVEHDVATVVELGPDGALSALIQECVAASDHAG
                     RLSAVPAMRRNQDEAQKVMTALAHVHVRGGAVDWRSFFAGTRAKQIELPTYAFQRQRYW
                     LNALRESSAGDMGRRVEAKFWGAVEHEDVESLARVLGIVDDGAAVDSLRSALPVLAGWQ
                     RTRTTESIMDQRCYRIGWRQVAGLPPMGTVFGTWLVFAPHGWSSEPEVVDCVTALRARG
                     ASVVLVEADPDPTSFGDRVRTLCSGLPDLVGVLSMLCLEESVLPGFSAVSRGFALTVEL
                     VRVLRAAGATARLWLLTCGGVSVGDVPVRPAQALAWGLGRVVGLEHPDWWGGLIDIPVL
                     FDEDAQERLSIVLAGLDEDEVAIRPDGMFARRLVRHTVSADVKKAWRPRGSVLVTGGTG
                     GLGAHVARWLADAGAEHVAMVSRRGEQAPSAEKLRTELEDLGTRVSIVSCDVTDREALA
                     EVLKALPAENPLTAVVHAAGVIETGDAAAMSLADFDHVLSAKVAGAANLDALLADVELD
                     AFVLFSSVSGVWGAGGHGAYAAANAYLDALAEQRRSRGLVATAVAWGPWAGEGMASGET
                     GDQLRRYGLSPMAPQHAIAGIRQAVEQDEISLVVADVDWARFSAGLLAARPRPLLNELA
                     EVKELLVDAQPEAGVLADASLEWRQRLSAAPRPTQEQLILELVRGETALVLGHPGAAAV
                     ASERAFKDSGFDSQAAVELRVRLNRATGLQLPSTIIFSHPTPAELAAELRARLLPESAG
                     AGIPEEDEARIRAALTSIPFPALREAGLVSPLLALAGHPVDSGISSDDAAATSIDAMDV
                     AGLVEAALGERES"
     misc_feature    21126..22379
                     /gene="spnA"
                     /note="Region: initiator decarboxylase domain"
     misc_feature    21126..24041
                     /gene="spnA"
                     /note="Region: loading module"
     aSDomain        21132..22382
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spnA_PKS_KS.1"
                     /domain_subtypes="Hybrid-KS"
                     /evalue="1.70E-164"
                     /label="spnA_PKS_KS.1"
                     /locus_tag="spnA"
                     /protein_end="424"
                     /protein_start="7"
                     /score="539.6"
                     /tool="antismash"
                     /translation="IAVIGLSCRLPQAPDPASFWRLLRTGTDAITTVPEGRWGDPLPGR
                     DAPKGPEWGGFLADVDCFDPEFFGISPREAATVDPQQRLALELAWEALEDAGIPAGELR
                     GTAAGVFMGAISDDYAALLRESPPEVAAQYRLTGTHRSLIANRVSYVLGLRGPSLTVDS
                     GQSSSLVGVHLASESLRRGECTIALAGGVNLNLAAESNSALMDFGALSPDGRCFTFDVR
                     ANGYVRGEGGGLVVLKKADQAHADGDRIYCLIRGSAVNNDGGGAGLTVPAADAQAELLR
                     QAYRNAGVDPAAVQYVELHGSATRVGDPVEAAALGAVLGAARRPGDELRVGSAKTNVGH
                     LEAAAGVTGLLKTALSIWHRELPPSLHFTAPNPEIPLDELNLRVQRDLRPWPESEGPLL
                     AGVSAFGMGGTNCHLVLS"
     aSModule        21132..24044
                     /complete
                     /domains="nrpspksdomains_spnA_PKS_KS.1"
                     /domains="nrpspksdomains_spnA_PKS_AT.1"
                     /domains="nrpspksdomains_spnA_ACP.1"
                     /locus_tags="spnA"
                     /monomer_pairings="mmal -> Me-mal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       21366..21392
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnA_0001"
                     /evalue="6.00E-02"
                     /label="PKSI-KS_m2"
                     /locus_tag="spnA"
                     /protein_end="94"
                     /protein_start="85"
                     /score="6.7"
                     /tool="antismash"
                     /translation="DPQQRLALE"
     CDS_motif       21597..21641
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnA_0002"
                     /evalue="1.60E-02"
                     /label="PKSI-KS_m3"
                     /locus_tag="spnA"
                     /protein_end="177"
                     /protein_start="162"
                     /score="8.2"
                     /tool="antismash"
                     /translation="GPSLTVDSGQSSSLV"
     CDS_motif       21786..21824
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnA_0003"
                     /evalue="4.60E-04"
                     /label="PKSI-KS_m4"
                     /locus_tag="spnA"
                     /protein_end="238"
                     /protein_start="225"
                     /score="13.3"
                     /tool="antismash"
                     /translation="FDVRANGYVRGEG"
     CDS_motif       22017..22064
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnA_0004"
                     /evalue="2.40E-02"
                     /label="PKSI-KS_m5"
                     /locus_tag="spnA"
                     /protein_end="318"
                     /protein_start="302"
                     /score="7.9"
                     /tool="antismash"
                     /translation="YVELHGSATRVGDPVE"
     CDS_motif       22125..22169
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnA_0005"
                     /evalue="3.40E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="spnA"
                     /protein_end="353"
                     /protein_start="338"
                     /score="10.2"
                     /tool="antismash"
                     /translation="GSAKTNVGHLEAAAG"
     CDS_motif       22689..22745
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnA_0006"
                     /evalue="1.70E-09"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="spnA"
                     /protein_end="545"
                     /protein_start="526"
                     /score="29.3"
                     /tool="antismash"
                     /translation="VFVFPGQGSQWIGMGRQLL"
     misc_feature    22692..23669
                     /gene="spnA"
                     /note="Region: initator acyltransferase domain"
     aSDomain        22695..23582
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spnA_PKS_AT.1"
                     /evalue="4.70E-111"
                     /label="spnA_PKS_AT.1"
                     /locus_tag="spnA"
                     /protein_end="824"
                     /protein_start="528"
                     /score="362.7"
                     /specificity="substrate consensus: mmal"
                     /specificity="PKS signature: Methylmalonyl-CoA"
                     /specificity="Minowa: mmal"
                     /tool="antismash"
                     /translation="VFPGQGSQWIGMGRQLLETSEVFAASMSDCADALAPHLDWSLLDV
                     LRNAAGAAHLDHDDVVQPALFAIMVSLAELWRSWGVRPVAVVGHSQGEIAAACVAGALS
                     VRDAARVVAVRSRLLTALAGSGAMASLQHPAEEVRQILLPWRDRIGVAGVNGPSSTLVS
                     GDREAMAELLAECADRELRMRRIPVEYASHSPHIEVVRDELLGLLAPVEPRTGSIPIYS
                     TTTGDLLDRPMDADYWYRNLRQPVLFEAAVEALLKRGYDAFIEISPHPVLTANIQETAV
                     RAGREVVALGTLRRG"
     CDS_motif       22863..22928
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnA_0007"
                     /evalue="2.70E-09"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="spnA"
                     /protein_end="606"
                     /protein_start="584"
                     /score="29.2"
                     /tool="antismash"
                     /translation="HDDVVQPALFAIMVSLAELWRS"
     CDS_motif       22932..23042
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnA_0008"
                     /evalue="9.50E-18"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="spnA"
                     /protein_end="644"
                     /protein_start="607"
                     /score="56.1"
                     /tool="antismash"
                     /translation="GVRPVAVVGHSQGEIAAACVAGALSVRDAARVVAVRS"
     CDS_motif       23148..23189
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnA_0009"
                     /evalue="6.70E-02"
                     /label="PKSI-AT-mM_m5"
                     /locus_tag="spnA"
                     /protein_end="693"
                     /protein_start="679"
                     /score="6.3"
                     /tool="antismash"
                     /translation="AGVNGPSSTLVSGD"
     CDS_motif       23256..23288
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnA_0010"
                     /evalue="4.90E-03"
                     /label="PKSI-AT-mM_m6"
                     /locus_tag="spnA"
                     /protein_end="726"
                     /protein_start="715"
                     /score="9.9"
                     /tool="antismash"
                     /translation="VEYASHSPHIE"
     CDS_motif       23391..23438
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnA_0011"
                     /evalue="3.30E-05"
                     /label="PKSI-AT-mM_m8"
                     /locus_tag="spnA"
                     /protein_end="776"
                     /protein_start="760"
                     /score="16.0"
                     /tool="antismash"
                     /translation="MDADYWYRNLRQPVLF"
     CDS_motif       23658..23690
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnA_0012"
                     /evalue="9.80E+00"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="spnA"
                     /protein_end="860"
                     /protein_start="849"
                     /score="-0.1"
                     /tool="antismash"
                     /translation="VFAGTGAQRVD"
     misc_feature    23793..24041
                     /gene="spnA"
                     /note="Region: initiator ACP domain"
     aSDomain        23835..24044
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spnA_ACP.1"
                     /evalue="1.30E-27"
                     /label="spnA_ACP.1"
                     /locus_tag="spnA"
                     /protein_end="978"
                     /protein_start="908"
                     /score="87.8"
                     /tool="antismash"
                     /translation="TMIRAQAAVVLGHSDPKEVDPDRTFKDLGFDSSMVVELCDRLNAA
                     TGLRLAPSVVFDCPTPDKLARQVRT"
     misc_feature    24102..25349
                     /gene="spnA"
                     /note="Region: ketosynthase domain 1"
     misc_feature    24102..28649
                     /gene="spnA"
                     /note="Region: extender module 1"
     aSDomain        24108..25358
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spnA_PKS_KS.2"
                     /domain_subtypes="Modular-KS"
                     /evalue="2.80E-182"
                     /label="spnA_PKS_KS.2"
                     /locus_tag="spnA"
                     /protein_end="1416"
                     /protein_start="999"
                     /score="598.2"
                     /tool="antismash"
                     /translation="IAVIGMGCRFPGGVSSPEELWQLVAAGRDVVSEFPADRGWDLERA
                     GTSHVRAGGFLHGAPDFDPGFFRISPREALAMDPQQRLLLEIAWEAVERGGINPQHLHG
                     SQTGVFVGATSLDYGPRLHEASEEAAGYVLTGSTTSVASGRVAYSFGFEGPAVTVDTAC
                     SSSLVALHLACQSLRSGECDLALAGGVTVMATPGMFVEFSRQRGLAPDGRCKSFAEAAD
                     GTGWSEGAGLVLLERLSDARRNGHEVLAVVRGSAVNQDGASNGLTAPNGSSQQRVIAQA
                     LASAGLSVSDVDAVEAHGTGTRLGDPIEAQALIATYGQGRLPERPLWLGSMKSNIGHAQ
                     AAAGIAGVMKMVMAMRHGQLPRTLHVDEPTSGVDWSAGTVQLLTENTPWPGSGRVRRVG
                     VSSFGISGTNAHVILEQP"
     aSModule        24108..28661
                     /complete
                     /domains="nrpspksdomains_spnA_PKS_KS.2"
                     /domains="nrpspksdomains_spnA_PKS_AT.2"
                     /domains="nrpspksdomains_spnA_PKS_KR.1"
                     /domains="nrpspksdomains_spnA_PKS_PP.1"
                     /locus_tags="spnA"
                     /monomer_pairings="mal -> ohmal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       24339..24365
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnA_0013"
                     /evalue="4.50E-02"
                     /label="PKSI-KS_m2"
                     /locus_tag="spnA"
                     /protein_end="1085"
                     /protein_start="1076"
                     /score="7.0"
                     /tool="antismash"
                     /translation="DPQQRLLLE"
     CDS_motif       24567..24614
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnA_0014"
                     /evalue="1.40E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="spnA"
                     /protein_end="1168"
                     /protein_start="1152"
                     /score="20.2"
                     /tool="antismash"
                     /translation="GPAVTVDTACSSSLVA"
     CDS_motif       24756..24794
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnA_0015"
                     /evalue="1.10E+00"
                     /label="PKSI-KS_m4"
                     /locus_tag="spnA"
                     /protein_end="1228"
                     /protein_start="1215"
                     /score="3.3"
                     /tool="antismash"
                     /translation="FAEAADGTGWSEG"
     CDS_motif       24990..25034
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnA_0016"
                     /evalue="6.60E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="spnA"
                     /protein_end="1308"
                     /protein_start="1293"
                     /score="12.0"
                     /tool="antismash"
                     /translation="VEAHGTGTRLGDPIE"
     CDS_motif       25095..25139
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnA_0017"
                     /evalue="5.00E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="spnA"
                     /protein_end="1343"
                     /protein_start="1328"
                     /score="9.7"
                     /tool="antismash"
                     /translation="GSMKSNIGHAQAAAG"
     CDS_motif       25683..25736
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnA_0018"
                     /evalue="1.10E-05"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="spnA"
                     /protein_end="1542"
                     /protein_start="1524"
                     /score="17.8"
                     /tool="antismash"
                     /translation="FVFSGQGGQWLGMGRGLY"
     misc_feature    25683..26684
                     /gene="spnA"
                     /note="Region: acyltransferase domain 1"
     aSDomain        25686..26588
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spnA_PKS_AT.2"
                     /evalue="5.30E-103"
                     /label="spnA_PKS_AT.2"
                     /locus_tag="spnA"
                     /protein_end="1826"
                     /protein_start="1525"
                     /score="336.3"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="VFSGQGGQWLGMGRGLYRAFPVFAAAFDEACAELDAHLGQEIGVR
                     EVVSGSDAQLLDRTLWAQSGLFALQVGLLKLLDSWGVRPSVVLGHSVGELAAAFAAGVV
                     SLSGAARLVAGRARLMQALPSGGGMLAVPAGEELLWSLLADQGDRVGIAAVNAAGSVVL
                     SGDRDVLDDLAGRLDGQGIRSRWLRVSHAFHSYRMDPMLAEFAELARTVDYRRCEVPIV
                     STLTGDLDDAGRMSGPDYWVRQVREPVRFADGVQALVEHDVATVVELGPDGALSALIQE
                     CVAASDHAGRLSAVPAMRRN"
     CDS_motif       25869..25913
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnA_0019"
                     /evalue="2.00E+01"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="spnA"
                     /protein_end="1601"
                     /protein_start="1586"
                     /score="-0.6"
                     /tool="antismash"
                     /translation="AQSGLFALQVGLLKL"
     CDS_motif       25926..26048
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnA_0020"
                     /evalue="7.70E-18"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="spnA"
                     /protein_end="1646"
                     /protein_start="1605"
                     /score="56.6"
                     /tool="antismash"
                     /translation="GVRPSVVLGHSVGELAAAFAAGVVSLSGAARLVAGRARLMQ"
     CDS_motif       26142..26183
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnA_0021"
                     /evalue="3.00E-01"
                     /label="PKSI-AT-mM_m5"
                     /locus_tag="spnA"
                     /protein_end="1691"
                     /protein_start="1677"
                     /score="4.5"
                     /tool="antismash"
                     /translation="AAVNAAGSVVLSGD"
     CDS_motif       26403..26438
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnA_0022"
                     /evalue="8.60E-05"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="spnA"
                     /protein_end="1776"
                     /protein_start="1764"
                     /score="15.9"
                     /tool="antismash"
                     /translation="YWVRQVREPVRF"
     CDS_motif       26724..26750
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnA_0023"
                     /evalue="1.80E+01"
                     /label="PKSI-AT-mM_m8"
                     /locus_tag="spnA"
                     /protein_end="1880"
                     /protein_start="1871"
                     /score="-0.6"
                     /tool="antismash"
                     /translation="RYWLNALRE"
     misc_feature    27582..28121
                     /gene="spnA"
                     /note="Region: ketoreductase domain 1"
     aSDomain        27588..28121
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spnA_PKS_KR.1"
                     /evalue="7.20E-60"
                     /label="spnA_PKS_KR.1"
                     /locus_tag="spnA"
                     /protein_end="2337"
                     /protein_start="2159"
                     /score="193.9"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: A2"
                     /tool="antismash"
                     /translation="GSVLVTGGTGGLGAHVARWLADAGAEHVAMVSRRGEQAPSAEKLR
                     TELEDLGTRVSIVSCDVTDREALAEVLKALPAENPLTAVVHAAGVIETGDAAAMSLADF
                     DHVLSAKVAGAANLDALLADVELDAFVLFSSVSGVWGAGGHGAYAAANAYLDALAEQRR
                     SRGLVATAVAWGPWA"
     CDS_motif       27591..27689
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnA_0024"
                     /evalue="2.10E-14"
                     /label="PKSI-KR_m1"
                     /locus_tag="spnA"
                     /protein_end="2193"
                     /protein_start="2160"
                     /score="46.0"
                     /tool="antismash"
                     /translation="SVLVTGGTGGLGAHVARWLADAGAEHVAMVSRR"
     CDS_motif       27966..28076
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnA_0025"
                     /evalue="2.50E-19"
                     /label="PKSI-KR_m4"
                     /locus_tag="spnA"
                     /protein_end="2322"
                     /protein_start="2285"
                     /score="61.8"
                     /tool="antismash"
                     /translation="LDAFVLFSSVSGVWGAGGHGAYAAANAYLDALAEQRR"
     misc_feature    28404..28649
                     /gene="spnA"
                     /note="Region: ACP domain 1"
     aSDomain        28404..28661
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spnA_PKS_PP.1"
                     /evalue="1.10E-26"
                     /label="spnA_PKS_PP.1"
                     /locus_tag="spnA"
                     /protein_end="2517"
                     /protein_start="2431"
                     /score="84.8"
                     /tool="antismash"
                     /translation="LSAAPRPTQEQLILELVRGETALVLGHPGAAAVASERAFKDSGFD
                     SQAAVELRVRLNRATGLQLPSTIIFSHPTPAELAAELRARL"
     aSDomain        28695..28886
                     /aSDomain="PKS_Docking_Cterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spnA_PKS_Docking_Cterm.1"
                     /evalue="3.60E-09"
                     /label="spnA_PKS_Docking_Cterm.1"
                     /locus_tag="spnA"
                     /protein_end="2592"
                     /protein_start="2528"
                     /score="29.3"
                     /tool="antismash"
                     /translation="EDEARIRAALTSIPFPALREAGLVSPLLALAGHPVDSGISSDDAA
                     ATSIDAMDVAGLVEAALGE"
     gene            28916..35374
                     /gene="spnB"
     CDS             28916..35374
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (38-463). E-value:
                     2.1e-182. Score: 598.6. Matches aSDomain:
                     nrpspksdomains_spnB_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (572-873). E-value: 4.1e-103.
                     Score: 336.7. Matches aSDomain:
                     nrpspksdomains_spnB_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (939-1102). E-value: 2.3e-63.
                     Score: 205.4. Matches aSDomain:
                     nrpspksdomains_spnB_PKS_DH.1"
                     /NRPS_PKS="Domain: PKS_ER (1412-1715). E-value: 4.6e-115.
                     Score: 375.9. Matches aSDomain:
                     nrpspksdomains_spnB_PKS_ER.1"
                     /NRPS_PKS="Domain: PKS_KR (1724-1902). E-value: 1.7e-60.
                     Score: 195.9. Matches aSDomain:
                     nrpspksdomains_spnB_PKS_KR.1"
                     /NRPS_PKS="Domain: ACP (2001-2073). E-value: 5.1e-30.
                     Score: 95.5. Matches aSDomain: nrpspksdomains_spnB_ACP.1"
                     /NRPS_PKS="Domain: PKS_Docking_Cterm (2083-2149). E-value:
                     2.6e-13. Score: 42.5. Matches aSDomain:
                     nrpspksdomains_spnB_PKS_Docking_Cterm.1"
                     /codon_start=1
                     /gene="spnB"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     mod_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 287.9; E-value:
                     2.3e-87)"
                     /gene_kind="biosynthetic"
                     /note="probably involved in spinosyn aglycone biosynthesis"
                     /product="polyketide synthase extender module 2"
                     /protein_id="AAG23265.1"
                     /sec_met_domain="mod_KS (E-value: 1.2e-228, bitscore:
                     749.6, seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 1.7e-103, bitscore:
                     336.7, seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_N (E-value: 6.9e-09, bitscore: 26.2,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 8.5e-17, bitscore:
                     52.0, seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 3.3e-60, bitscore:
                     193.6, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1e-15, bitscore:
                     48.7, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVTTSYEEVVEALRASLKENERLRRGRDRFSAEKDDPIAIVAMS
                     CRYPGQVSSPEDLWQLAAGGVDAISEVPGDRGWDLDGVFVPDSDRPGTSYACAGGFLQG
                     VSEFDAGFFGISPREALAMDPQQRLLLEVAWEVFERAGLEQRSTRGSRVGVFVGTNGQD
                     YASWLRTPPPAVAGHVLTGGAAAVLSGRVAYSFGFEGPAVTVDTACSSSLVALHLAGQA
                     LRAGECDLALAGGVTVMSTPKVFLEFSRQRGLAPDGRCKSFAAGADGTGWGEGAGLLLL
                     ERLSDARRNGHEVLAVVRGSAVNQDGASNGLTAPNGSSQQRVITQALASAGLSVSDVDA
                     VEAHGTGTRLGDPIEAQALIATYGRDRDPGRPLWLGSVKSNIGHTQAAAGVAGVIKMVM
                     AMRHGQLPRTLHVESPSPEVDWSAGTVQLLTENTPWPRSGRVRRVGVSSFGISGTNAHV
                     ILEQPPGVPSQSAGPGSGSVVDVPVVPWMVSGKTPEALSAQATALMTYLDERPDVSSLD
                     VGYSLALTRSALDERAVVLGSDRETLLCGVKALSAGHEASGLVTGSVGAGGRIGFVFSG
                     QGGQWLGMGRGLYRAFPVFAAAFDEACAELDAHLGQEIGVREVVSGSDAQLLDRTLWAQ
                     SGLFALQVGLLKLLDSWGVRPSVVLGHSVGELAAAFAAGVVSLSGAARLVAGRARLMQA
                     LPSGGGMLAVPAGEELLWSLLADQGDRVGIAAVNAAGSVVLSGDRDVLDDLAGRLDGQG
                     IRSRWLRVSHAFHSYRMDPMLAEFAELARTVDYRRCEVPIVSTLTGDLDDAGRMSGPDY
                     WVRQVREPVRFADGVQALVEHDVATVVELGPDGALSALIQECVAASDHAGRLSAVPAMR
                     RNQDEAQKVMTALAHVHVRGGAVDWRSFFAGTGAKQIELPTYAFQRQRYWLVPSDSGDV
                     TGAGLAGAEHPLLGAVVPVAGGDEVLLTGRISVRTHPWLAEHRVLGEVIVAGTALLEIA
                     LHAGERLGCERVEELTLEAPLVLPERGAIQVQLRVGAPENSGRRPMALYSRPEGAAEHD
                     WTRHATGRLAPGRGEAAGDLADWPAPGALPVDLDEFYRDLAELGLEYGPIFQGLKAAWR
                     QGDEVYAEAALPGTEDSGFGVHPALLDAALHATAVRDMDDARLPFQWEGVSLHAKAAPA
                     LRVRVVPAGDDAKSLLVCDGTGRPVISVDRLVLRSAAARRTGARRQAHQARLYRLSWPT
                     VQLPTSAQPPSCVLLGTSEVSADIQVYPDLRSLTAALDAGAEPPGVVIAPTPPGGGRTA
                     DVRETTRHALDLVQGWLSDQRLNESRLLLVTQGAVAVEPGEPVTDLAQAALWGLLRSTQ
                     TEHPDRFVLVDVPEPAQLLPALPGVLACGEPQLALRRGGAHAPRLAGLGSDDVLPVPDG
                     TGWRLEATRPGSLDGLALVDEPTATAPLGDGEVRIAMRAAGVNFRDALIALGMYPGVAS
                     LGSEGAGVVVETGPGVTGLAPGDRVMGMIPKAFGPLAVADHRMVTRIPAGWSFARAASV
                     PIVFLTAYYALVDLAGLRPGESLLVHSAAGGVGMAAIQLARHLGAEVYATASEDKWQAV
                     ELSREHLASSRTCDFEQQFLGATGGRGVDVVLNSLAGEFADASLRMLPRGGRFLELGKT
                     DVRDPVEVADAHPGVSYQAFDTVEAGPQRIGEMLHELVELFEGRVLEPLPVTAWDVRQA
                     PEALRHLSQARHVGKLVLTMPPVWDAAGTVLVTGGTGALGAEVARHLVIERGVRNLVLV
                     SRRGPAASGAAELVAQLTAYGAEVSLQACDVADRETLAKVLASIPDEHPLTAVVHAAGV
                     LDDGVSESLTVERLDQVLRPKVDGARNLLELIDPDVALVLFSSVSGVLGSGGQGNYAAA
                     NSFLDALAQQRQSRGLPTRSLAWGPWAEHGMASTLREAEQDRLARSGLLPISTEEGLSQ
                     FDAACGGAHTVVAPVRFSRLSDGNAIKFSVLQGLVGPHRVNKAATADDAESLRKRLGRL
                     PDAEQHRILLDLVRMHVAAVLGFAGSQEITADGTFKVLGFDSLTVVELRNRINGATGLR
                     LPATLVFNYPTPDALAAHLVTALSADRLAGTFEELDRWAANLPTLARDEATRAQITTRL
                     QAILQSLADVSGGTGGGSVPDRLRSATDDELFQLLDNDLELP"
     misc_feature    29024..30295
                     /gene="spnB"
                     /note="Region: ketosynthase domain 2"
     misc_feature    29024..35125
                     /gene="spnB"
                     /note="Region: extender module 2"
     aSDomain        29030..30304
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spnB_PKS_KS.1"
                     /domain_subtypes="Modular-KS"
                     /evalue="2.10E-182"
                     /label="spnB_PKS_KS.1"
                     /locus_tag="spnB"
                     /protein_end="463"
                     /protein_start="38"
                     /score="598.6"
                     /tool="antismash"
                     /translation="IAIVAMSCRYPGQVSSPEDLWQLAAGGVDAISEVPGDRGWDLDGV
                     FVPDSDRPGTSYACAGGFLQGVSEFDAGFFGISPREALAMDPQQRLLLEVAWEVFERAG
                     LEQRSTRGSRVGVFVGTNGQDYASWLRTPPPAVAGHVLTGGAAAVLSGRVAYSFGFEGP
                     AVTVDTACSSSLVALHLAGQALRAGECDLALAGGVTVMSTPKVFLEFSRQRGLAPDGRC
                     KSFAAGADGTGWGEGAGLLLLERLSDARRNGHEVLAVVRGSAVNQDGASNGLTAPNGSS
                     QQRVITQALASAGLSVSDVDAVEAHGTGTRLGDPIEAQALIATYGRDRDPGRPLWLGSV
                     KSNIGHTQAAAGVAGVIKMVMAMRHGQLPRTLHVESPSPEVDWSAGTVQLLTENTPWPR
                     SGRVRRVGVSSFGISGTNAHVILEQP"
     aSModule        29030..35134
                     /complete
                     /domains="nrpspksdomains_spnB_PKS_KS.1"
                     /domains="nrpspksdomains_spnB_PKS_AT.1"
                     /domains="nrpspksdomains_spnB_PKS_DH.1"
                     /domains="nrpspksdomains_spnB_PKS_ER.1"
                     /domains="nrpspksdomains_spnB_PKS_KR.1"
                     /domains="nrpspksdomains_spnB_ACP.1"
                     /locus_tags="spnB"
                     /monomer_pairings="mal -> redmal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       29429..29488
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnB_0001"
                     /evalue="3.80E+00"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="spnB"
                     /protein_end="191"
                     /protein_start="171"
                     /score="0.8"
                     /tool="antismash"
                     /translation="PPAVAGHVLTGGAAAVLSGR"
     CDS_motif       29513..29560
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnB_0002"
                     /evalue="1.10E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="spnB"
                     /protein_end="215"
                     /protein_start="199"
                     /score="20.5"
                     /tool="antismash"
                     /translation="GPAVTVDTACSSSLVA"
     CDS_motif       29936..29980
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnB_0003"
                     /evalue="5.20E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="spnB"
                     /protein_end="355"
                     /protein_start="340"
                     /score="12.3"
                     /tool="antismash"
                     /translation="VEAHGTGTRLGDPIE"
     CDS_motif       30041..30085
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnB_0004"
                     /evalue="8.60E-04"
                     /label="PKSI-KS_m6"
                     /locus_tag="spnB"
                     /protein_end="390"
                     /protein_start="375"
                     /score="11.8"
                     /tool="antismash"
                     /translation="GSVKSNIGHTQAAAG"
     CDS_motif       30629..30682
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnB_0005"
                     /evalue="8.70E-06"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="spnB"
                     /protein_end="589"
                     /protein_start="571"
                     /score="18.1"
                     /tool="antismash"
                     /translation="FVFSGQGGQWLGMGRGLY"
     misc_feature    30629..31621
                     /gene="spnB"
                     /note="Region: acyltransferase domain 2"
     aSDomain        30632..31534
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spnB_PKS_AT.1"
                     /evalue="4.10E-103"
                     /label="spnB_PKS_AT.1"
                     /locus_tag="spnB"
                     /protein_end="873"
                     /protein_start="572"
                     /score="336.7"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="VFSGQGGQWLGMGRGLYRAFPVFAAAFDEACAELDAHLGQEIGVR
                     EVVSGSDAQLLDRTLWAQSGLFALQVGLLKLLDSWGVRPSVVLGHSVGELAAAFAAGVV
                     SLSGAARLVAGRARLMQALPSGGGMLAVPAGEELLWSLLADQGDRVGIAAVNAAGSVVL
                     SGDRDVLDDLAGRLDGQGIRSRWLRVSHAFHSYRMDPMLAEFAELARTVDYRRCEVPIV
                     STLTGDLDDAGRMSGPDYWVRQVREPVRFADGVQALVEHDVATVVELGPDGALSALIQE
                     CVAASDHAGRLSAVPAMRRN"
     CDS_motif       30872..30994
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnB_0006"
                     /evalue="6.30E-18"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="spnB"
                     /protein_end="693"
                     /protein_start="652"
                     /score="56.9"
                     /tool="antismash"
                     /translation="GVRPSVVLGHSVGELAAAFAAGVVSLSGAARLVAGRARLMQ"
     CDS_motif       31349..31384
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnB_0007"
                     /evalue="7.00E-05"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="spnB"
                     /protein_end="823"
                     /protein_start="811"
                     /score="16.2"
                     /tool="antismash"
                     /translation="YWVRQVREPVRF"
     misc_feature    31697..32254
                     /gene="spnB"
                     /note="Region: dehydratase domain 2"
     aSDomain        31733..32221
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spnB_PKS_DH.1"
                     /evalue="2.30E-63"
                     /label="spnB_PKS_DH.1"
                     /locus_tag="spnB"
                     /protein_end="1102"
                     /protein_start="939"
                     /score="205.4"
                     /tool="antismash"
                     /translation="HPLLGAVVPVAGGDEVLLTGRISVRTHPWLAEHRVLGEVIVAGTA
                     LLEIALHAGERLGCERVEELTLEAPLVLPERGAIQVQLRVGAPENSGRRPMALYSRPEG
                     AAEHDWTRHATGRLAPGRGEAAGDLADWPAPGALPVDLDEFYRDLAELGLEYGPIFQGL
                     "
     CDS_motif       31817..31891
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnB_0008"
                     /evalue="3.40E-07"
                     /label="PKSI-DH_m2"
                     /locus_tag="spnB"
                     /protein_end="992"
                     /protein_start="967"
                     /score="22.8"
                     /tool="antismash"
                     /translation="WLAEHRVLGEVIVAGTALLEIALHA"
     misc_feature    33035..34072
                     /gene="spnB"
                     /note="Region: enoylreductase domain 2"
     aSDomain        33152..34060
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spnB_PKS_ER.1"
                     /evalue="4.60E-115"
                     /label="spnB_PKS_ER.1"
                     /locus_tag="spnB"
                     /protein_end="1715"
                     /protein_start="1412"
                     /score="375.9"
                     /tool="antismash"
                     /translation="GSLDGLALVDEPTATAPLGDGEVRIAMRAAGVNFRDALIALGMYP
                     GVASLGSEGAGVVVETGPGVTGLAPGDRVMGMIPKAFGPLAVADHRMVTRIPAGWSFAR
                     AASVPIVFLTAYYALVDLAGLRPGESLLVHSAAGGVGMAAIQLARHLGAEVYATASEDK
                     WQAVELSREHLASSRTCDFEQQFLGATGGRGVDVVLNSLAGEFADASLRMLPRGGRFLE
                     LGKTDVRDPVEVADAHPGVSYQAFDTVEAGPQRIGEMLHELVELFEGRVLEPLPVTAWD
                     VRQAPEALRHLSQARHVGKLVL"
     CDS_motif       33464..33508
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnB_0009"
                     /evalue="2.10E-05"
                     /label="PKSI-ER_m4"
                     /locus_tag="spnB"
                     /protein_end="1531"
                     /protein_start="1516"
                     /score="17.7"
                     /tool="antismash"
                     /translation="AASVPIVFLTAYYAL"
     CDS_motif       33533..33595
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnB_0010"
                     /evalue="2.40E-09"
                     /label="PKSI-ER_m5"
                     /locus_tag="spnB"
                     /protein_end="1560"
                     /protein_start="1539"
                     /score="29.5"
                     /tool="antismash"
                     /translation="GESLLVHSAAGGVGMAAIQLA"
     CDS_motif       33605..33649
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnB_0011"
                     /evalue="2.50E-03"
                     /label="PKSI-ER_m6"
                     /locus_tag="spnB"
                     /protein_end="1578"
                     /protein_start="1563"
                     /score="10.8"
                     /tool="antismash"
                     /translation="GAEVYATASEDKWQA"
     CDS_motif       33719..33757
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnB_0012"
                     /evalue="1.00E-05"
                     /label="PKSI-ER_m7"
                     /locus_tag="spnB"
                     /protein_end="1614"
                     /protein_start="1601"
                     /score="17.8"
                     /tool="antismash"
                     /translation="TGGRGVDVVLNSL"
     CDS_motif       34013..34060
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnB_0013"
                     /evalue="2.30E-04"
                     /label="PKSI-ER_m9"
                     /locus_tag="spnB"
                     /protein_end="1715"
                     /protein_start="1699"
                     /score="14.3"
                     /tool="antismash"
                     /translation="ALRHLSQARHVGKLVL"
     misc_feature    34082..34621
                     /gene="spnB"
                     /note="Region: ketoreductase domain 2"
     aSDomain        34088..34621
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spnB_PKS_KR.1"
                     /evalue="1.70E-60"
                     /label="spnB_PKS_KR.1"
                     /locus_tag="spnB"
                     /protein_end="1902"
                     /protein_start="1724"
                     /score="195.9"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: B1"
                     /tool="antismash"
                     /translation="GTVLVTGGTGALGAEVARHLVIERGVRNLVLVSRRGPAASGAAEL
                     VAQLTAYGAEVSLQACDVADRETLAKVLASIPDEHPLTAVVHAAGVLDDGVSESLTVER
                     LDQVLRPKVDGARNLLELIDPDVALVLFSSVSGVLGSGGQGNYAAANSFLDALAQQRQS
                     RGLPTRSLAWGPWAE"
     CDS_motif       34091..34192
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnB_0014"
                     /evalue="1.50E-11"
                     /label="PKSI-KR_m1"
                     /locus_tag="spnB"
                     /protein_end="1759"
                     /protein_start="1725"
                     /score="36.8"
                     /tool="antismash"
                     /translation="TVLVTGGTGALGAEVARHLVIERGVRNLVLVSRR"
     CDS_motif       34472..34573
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnB_0015"
                     /evalue="2.00E-18"
                     /label="PKSI-KR_m4"
                     /locus_tag="spnB"
                     /protein_end="1886"
                     /protein_start="1852"
                     /score="59.0"
                     /tool="antismash"
                     /translation="LVLFSSVSGVLGSGGQGNYAAANSFLDALAQQRQ"
     misc_feature    34886..35125
                     /gene="spnB"
                     /note="Region: ACP domain 2"
     aSDomain        34919..35134
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spnB_ACP.1"
                     /evalue="5.10E-30"
                     /label="spnB_ACP.1"
                     /locus_tag="spnB"
                     /protein_end="2073"
                     /protein_start="2001"
                     /score="95.5"
                     /tool="antismash"
                     /translation="LDLVRMHVAAVLGFAGSQEITADGTFKVLGFDSLTVVELRNRING
                     ATGLRLPATLVFNYPTPDALAAHLVTA"
     aSDomain        35165..35362
                     /aSDomain="PKS_Docking_Cterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spnB_PKS_Docking_Cterm.1"
                     /evalue="2.60E-13"
                     /label="spnB_PKS_Docking_Cterm.1"
                     /locus_tag="spnB"
                     /protein_end="2149"
                     /protein_start="2083"
                     /score="42.5"
                     /tool="antismash"
                     /translation="EELDRWAANLPTLARDEATRAQITTRLQAILQSLADVSGGTGGGS
                     VPDRLRSATDDELFQLLDNDL"
     gene            35419..44931
                     /gene="spnC"
     CDS             35419..44931
                     /NRPS_PKS="Domain: PKS_Docking_Nterm (3-30). E-value:
                     1.3e-13. Score: 42.2. Matches aSDomain:
                     nrpspksdomains_spnC_PKS_Docking_Nterm.1"
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (35-458). E-value:
                     3.9e-187. Score: 614.2. Matches aSDomain:
                     nrpspksdomains_spnC_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (564-861). E-value: 8e-109.
                     Score: 355.4. Matches aSDomain:
                     nrpspksdomains_spnC_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_KR (1193-1367). E-value: 2e-55.
                     Score: 179.4. Matches aSDomain:
                     nrpspksdomains_spnC_PKS_KR.1"
                     /NRPS_PKS="Domain: ACP (1471-1543). E-value: 5e-32. Score:
                     101.9. Matches aSDomain: nrpspksdomains_spnC_ACP.1"
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (1563-1988). E-value:
                     1.1e-184. Score: 606.1. Matches aSDomain:
                     nrpspksdomains_spnC_PKS_KS.2"
                     /NRPS_PKS="Domain: PKS_AT (2099-2398). E-value: 2.5e-104.
                     Score: 340.7. Matches aSDomain:
                     nrpspksdomains_spnC_PKS_AT.2"
                     /NRPS_PKS="Domain: PKS_KR (2734-2912). E-value: 1.5e-60.
                     Score: 196.1. Matches aSDomain:
                     nrpspksdomains_spnC_PKS_KR.2"
                     /NRPS_PKS="Domain: PKS_PP (3004-3090). E-value: 1.3e-29.
                     Score: 94.2. Matches aSDomain:
                     nrpspksdomains_spnC_PKS_PP.1"
                     /NRPS_PKS="Domain: PKS_Docking_Cterm (3099-3168). E-value:
                     4.4e-15. Score: 48.2. Matches aSDomain:
                     nrpspksdomains_spnC_PKS_Docking_Cterm.1"
                     /codon_start=1
                     /gene="spnC"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     mod_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 300.1; E-value:
                     4.4e-91)"
                     /gene_kind="biosynthetic"
                     /note="probably involved in spinosyn aglycone biosynthesis"
                     /product="polyketide synthase extender modules 3-4"
                     /protein_id="AAG23266.1"
                     /sec_met_domain="mod_KS (E-value: 1.3e-234, bitscore:
                     769.3, seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 3.3e-109, bitscore:
                     355.4, seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 5.3e-62, bitscore:
                     199.5, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 4.5e-16, bitscore:
                     49.8, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNEEKLREYLRRALVDLHQARERLHEAESGEREPIAIVAMGCRY
                     PGGVQDPEGLWKLVASGGDAIGEFPADRGWHLDELYDPDPDQPGTCYTRHGGFLHDAGE
                     FDAGFFDISPREALAMDPQQRLLLEISWETVESAGMDPRSLRGSRTGVFAGLMYEGYDT
                     GAHRAGEGVEGYLGTGNAGSVASGRVAYAFGFEGPAVTVDTACSSSLVALHLACQSLRQ
                     GECDLALAGGVTVMSTPERFVEFSRQRGLAPDGRCKSFAAAADGTGWGEGAGLVLLERL
                     SDARRNGHRVLAVVRGSAVNQDGASNGLTAPNGLAQERVIQQVLTSAGLSASDVDAVEA
                     HGTGTRLGDPIEAQALIAAYGQDRDRDRPLWLGSVKSNIGHTQAAAGVAGVIKMVMAMR
                     HGELPRTLHVDEPNSHVDWSAGAVRLLTENIRWPGTGTRRAGVSSFGVSGTNAHVILEH
                     DPLAVTENEEAAQSPAPGIVPWALSGRSSTALRAQAERLRELCEQTDPDPVDVGFSLAA
                     TRTAWEHRAVVLGRDSATLRSGLGVVASGEPAVDVVEGSVLDGEVVFVFPGQGWQWAGM
                     AVDLLDASPTFARHMDECATALRRYVDWSLVDVLRGAENSPPLDRVDVLQPASFAVMVS
                     LAEVWRSYGVRPAAVVGHSQGEIAAACAAGVLPLEDAARLVALRSRALKGLSGRGGMAS
                     LACPADEVAALFAGSGGRLEVAAINGPRSVVVSGDLEAVDELLAECAEKDMRARRIPVD
                     YASHSAHVEVVRSPVLAAAAGVRHRDGQVPWWSTVIGDWVDPARLDGEYWYRNLRQPVR
                     FEHAVQGLVERGFGLFIEMSAHPVLTTAVEETGAESETAVAAVGTLRRDSGGLRRLLHS
                     LAEAYVRGATVDWAVAFGGAGRRLDLPTYPFQRQRYWLDKGAASDEARAVSDPAAGWFW
                     QAVARQDLKSVSDALDLDADAPLSATLPALSVWHRQERERVLADGWRYRVDWVRVAPQP
                     VRRTRETWLLVVPPGGIEEALVERLTDALNTRGISTLRLDVPPAATSGELATELRAAAD
                     GDPVKAILSLTALDERPHPECKDVPSGIALLLNLVKALGEADLRIPLWTITRGAVKAGP
                     ADRLLRPMQAQAWGLGRVAALEHPERWGGLIDLPDSLDGDVLTRLGEALTNGLAEDQLA
                     IRQSGVLARRLVPAPANQPAGRKWRPRGSALITGGLGAVGAQVARWLAEIGAERIVLTS
                     RRGNQAAGAAELEAELRALGAQVSIVACDVTDRAEMSALLAEFDVTAVFHAAGVGRLLP
                     LAETDQNGLAEICAAKVRGAQVLDELCDSTDLDAFVLFSSGAGVWGGGGQGAYGAANAF
                     LDTLAEQRRARGLPATSISWGSWAGGGMADGAAGEHLRRRGIRPMPAASAILALQEVLD
                     QDETCVSIADVDWDRFVPTFAATRATRLFDEVPAARKAMPANGPAEPGGSPFARNLAEL
                     PEAQRRHELVDLVCAQVATVLGHGSREEVQPERAFRALGFDSLMAVDLRNRLTTATGLR
                     LPTTTVFDYPNPAALAAHLLEELVGDVASAAVTAASAPASDEPIAIVAMSCRFPGGAHS
                     PEDLWRLVAAGTEVIGEFPSDRGWDAEGLYDPDASRPGTTYARMAGFLYDAGEFDADLF
                     GISPREALAMDPQQRLVLEIAWEALERAGIDPLSLKGSGVGTYIGAGSRGYATDVRQFP
                     EEAEGYLLTGTSASVLSGRVAYSFGFEGPAVTVDTACSSSLVALHLACQSLRSGECDLA
                     LAGGVTVMSTPEMFVEFSRQRGLAPDGRCKSFAESADGTGWGEGAGLLLLERLSDAHRN
                     GHRVLAVVRGSAVNQDGASNGLAAPNGPSQQRVINQALANAALSASDVDAVEAHGTGTR
                     LGDPIEAQALIATYGQARERDRPLWLGSVKSNIGHTQAAAGVAGVIKMVMAMRHGQLPA
                     SLHADEPTSEVDWSSGAVRLLAEQVPWPESDRVRRVGVSSFGISGTNAHVILEQATNAP
                     DSTAETDKTESGSTVDIPVVPWLVSGKTTDSLRGQAERVLSQVESRPEQRSLDVAYSLA
                     SGRAALDERAVVLGADRGELVAGLAALAAGQEASGVISGTRASARFGFVFSGQGGQWLG
                     MGRALYSKFPVFAAAFDEACAELEAHLGEDRRVRDVVFGSDAQLLDQTLWAQSGLFALQ
                     AGLLGLLGSWGVRPDVVMGHSVGELAAAFAAGVLSLRDAARLVAARARLMQALPSDGAM
                     LAVAAGEDLVRPLLAGREESVSVAALNAPGSVVLSGDREVLASIVGRLTELRVRTRRLR
                     VSHAFHSHRMDPMLGEFAQIAESAEFGKPTTPLVSTLTGELDRAAEMSTPGYWVRQARE
                     PVRFADGVQALAAQGIGTVVELGPDGTLAALVRECATESDRVGRISSIPLMRRERDETR
                     SVMTALAHLHTRGGEVDWQAFFAGTGARQLELPTYAFQRQHYWIESSARPARDRADIGE
                     VAEQFWTAVDQGDLATLVAALDLGADDDTCASLSDVLPALSSWRSGLRNRSLVDSCRYR
                     ISWHSSREVPAPKISGTWLLVVPGAADDGLVTALTSSLVGGGAEVVRIGLSEEDPHRED
                     VAQRLANALTDAGQLGGVLSLLGLDESPAPGFSCLPTGFALTVQLLRALRKADVEAPFW
                     AVTRGGVALEDVRVSPEQALVWGLLRVAGLEHPEFWGGLIDLPSDWDDRLGARLAGVLA
                     DGGEDQVAIRRGGVFVRRLERAGASGAGSVWRPRGTVLVTGGTGGLGAHVARWLAGAGA
                     EHVVLTSRRGADAPGAGELRAELEALGARVSIVPCDVADRDAVAGVLAGIGGECPLTAV
                     VHAAGVGEAGDVVEMGLADFAAVLSAKVRGAANLDELLADSELDAFVMFSSVSGVWGAG
                     GQGAYAAANAYLDALAEQRRARGLVGTAVAWGPWAGDGMAAGETGAQLHRMGLASMEPS
                     AALLALQGALDRDETSLVVADVDWARFAPAFTSARRRPLLDTIDEARAALETTGEQAGT
                     GKPVELTQRLAGLSRKERDDAVLDLVRAETAAVLGRDDATALAPSRPFQELGFDSLMAV
                     ELRNRLNTATGIQLPASTIFDYPNAESLSRHLCAELFPTETTVDSALAELDRIEQQLSM
                     LTGEARARDRIATRLRALHEKWNSAAEVPTGADVLSTLDSATHDEIFEFIDNELDLS"
     aSDomain        35428..35508
                     /aSDomain="PKS_Docking_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spnC_PKS_Docking_Nterm.1"
                     /evalue="1.30E-13"
                     /label="spnC_PKS_Docking_Nterm.1"
                     /locus_tag="spnC"
                     /protein_end="30"
                     /protein_start="3"
                     /score="42.2"
                     /tool="antismash"
                     /translation="EEKLREYLRRALVDLHQARERLHEAES"
     misc_feature    35518..36786
                     /gene="spnC"
                     /note="Region: ketosynthase domain 3"
     misc_feature    35518..40035
                     /gene="spnC"
                     /note="Region: extender module 3"
     aSDomain        35524..36792
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spnC_PKS_KS.1"
                     /domain_subtypes="Modular-KS"
                     /evalue="3.90E-187"
                     /label="spnC_PKS_KS.1"
                     /locus_tag="spnC"
                     /protein_end="458"
                     /protein_start="35"
                     /score="614.2"
                     /tool="antismash"
                     /translation="IAIVAMGCRYPGGVQDPEGLWKLVASGGDAIGEFPADRGWHLDEL
                     YDPDPDQPGTCYTRHGGFLHDAGEFDAGFFDISPREALAMDPQQRLLLEISWETVESAG
                     MDPRSLRGSRTGVFAGLMYEGYDTGAHRAGEGVEGYLGTGNAGSVASGRVAYAFGFEGP
                     AVTVDTACSSSLVALHLACQSLRQGECDLALAGGVTVMSTPERFVEFSRQRGLAPDGRC
                     KSFAAAADGTGWGEGAGLVLLERLSDARRNGHRVLAVVRGSAVNQDGASNGLTAPNGLA
                     QERVIQQVLTSAGLSASDVDAVEAHGTGTRLGDPIEAQALIAAYGQDRDRDRPLWLGSV
                     KSNIGHTQAAAGVAGVIKMVMAMRHGELPRTLHVDEPNSHVDWSAGAVRLLTENIRWPG
                     TGTRRAGVSSFGVSGTNAHVILEH"
     aSModule        35524..40047
                     /complete
                     /domains="nrpspksdomains_spnC_PKS_KS.1"
                     /domains="nrpspksdomains_spnC_PKS_AT.1"
                     /domains="nrpspksdomains_spnC_PKS_KR.1"
                     /domains="nrpspksdomains_spnC_ACP.1"
                     /locus_tags="spnC"
                     /monomer_pairings="mmal -> Me-ohmal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       35779..35805
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnC_0001"
                     /evalue="5.80E-02"
                     /label="PKSI-KS_m2"
                     /locus_tag="spnC"
                     /protein_end="129"
                     /protein_start="120"
                     /score="6.7"
                     /tool="antismash"
                     /translation="DPQQRLLLE"
     CDS_motif       36007..36054
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnC_0002"
                     /evalue="1.70E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="spnC"
                     /protein_end="212"
                     /protein_start="196"
                     /score="19.9"
                     /tool="antismash"
                     /translation="GPAVTVDTACSSSLVA"
     CDS_motif       36196..36234
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnC_0003"
                     /evalue="5.80E-01"
                     /label="PKSI-KS_m4"
                     /locus_tag="spnC"
                     /protein_end="272"
                     /protein_start="259"
                     /score="4.2"
                     /tool="antismash"
                     /translation="FAAAADGTGWGEG"
     CDS_motif       36430..36474
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnC_0004"
                     /evalue="8.50E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="spnC"
                     /protein_end="352"
                     /protein_start="337"
                     /score="11.7"
                     /tool="antismash"
                     /translation="VEAHGTGTRLGDPIE"
     CDS_motif       36535..36579
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnC_0005"
                     /evalue="1.40E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="spnC"
                     /protein_end="387"
                     /protein_start="372"
                     /score="11.2"
                     /tool="antismash"
                     /translation="GSVKSNIGHTQAAAG"
     CDS_motif       37105..37161
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnC_0006"
                     /evalue="2.70E-09"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="spnC"
                     /protein_end="581"
                     /protein_start="562"
                     /score="28.7"
                     /tool="antismash"
                     /translation="VFVFPGQGWQWAGMAVDLL"
     misc_feature    37108..38097
                     /gene="spnC"
                     /note="Region: acyltransferase domain 3"
     aSDomain        37111..38001
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spnC_PKS_AT.1"
                     /evalue="8.00E-109"
                     /label="spnC_PKS_AT.1"
                     /locus_tag="spnC"
                     /protein_end="861"
                     /protein_start="564"
                     /score="355.4"
                     /specificity="substrate consensus: mmal"
                     /specificity="PKS signature: Methylmalonyl-CoA"
                     /specificity="Minowa: mmal"
                     /tool="antismash"
                     /translation="VFPGQGWQWAGMAVDLLDASPTFARHMDECATALRRYVDWSLVDV
                     LRGAENSPPLDRVDVLQPASFAVMVSLAEVWRSYGVRPAAVVGHSQGEIAAACAAGVLP
                     LEDAARLVALRSRALKGLSGRGGMASLACPADEVAALFAGSGGRLEVAAINGPRSVVVS
                     GDLEAVDELLAECAEKDMRARRIPVDYASHSAHVEVVRSPVLAAAAGVRHRDGQVPWWS
                     TVIGDWVDPARLDGEYWYRNLRQPVRFEHAVQGLVERGFGLFIEMSAHPVLTTAVEETG
                     AESETAVAAVGTLRRD"
     CDS_motif       37273..37344
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnC_0007"
                     /evalue="1.10E-08"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="spnC"
                     /protein_end="642"
                     /protein_start="618"
                     /score="27.4"
                     /tool="antismash"
                     /translation="LDRVDVLQPASFAVMVSLAEVWRS"
     CDS_motif       37348..37464
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnC_0008"
                     /evalue="9.90E-18"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="spnC"
                     /protein_end="682"
                     /protein_start="643"
                     /score="56.3"
                     /tool="antismash"
                     /translation="GVRPAAVVGHSQGEIAAACAAGVLPLEDAARLVALRSRA"
     CDS_motif       37564..37602
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnC_0009"
                     /evalue="2.10E-04"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="spnC"
                     /protein_end="728"
                     /protein_start="715"
                     /score="14.4"
                     /tool="antismash"
                     /translation="AAINGPRSVVVSG"
     CDS_motif       37672..37704
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnC_0010"
                     /evalue="1.40E-03"
                     /label="PKSI-AT-mM_m6"
                     /locus_tag="spnC"
                     /protein_end="762"
                     /protein_start="751"
                     /score="11.5"
                     /tool="antismash"
                     /translation="VDYASHSAHVE"
     CDS_motif       37810..37857
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnC_0011"
                     /evalue="1.40E-05"
                     /label="PKSI-AT-mM_m8"
                     /locus_tag="spnC"
                     /protein_end="813"
                     /protein_start="797"
                     /score="17.1"
                     /tool="antismash"
                     /translation="LDGEYWYRNLRQPVRF"
     misc_feature    38992..39528
                     /gene="spnC"
                     /note="Region: ketoreductase domain 3"
     aSDomain        38998..39519
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spnC_PKS_KR.1"
                     /evalue="2.00E-55"
                     /label="spnC_PKS_KR.1"
                     /locus_tag="spnC"
                     /protein_end="1367"
                     /protein_start="1193"
                     /score="179.4"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: A1"
                     /tool="antismash"
                     /translation="GSALITGGLGAVGAQVARWLAEIGAERIVLTSRRGNQAAGAAELE
                     AELRALGAQVSIVACDVTDRAEMSALLAEFDVTAVFHAAGVGRLLPLAETDQNGLAEIC
                     AAKVRGAQVLDELCDSTDLDAFVLFSSGAGVWGGGGQGAYGAANAFLDTLAEQRRARGL
                     PATSISWGSWA"
     CDS_motif       39007..39099
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnC_0012"
                     /evalue="5.60E-12"
                     /label="PKSI-KR_m1"
                     /locus_tag="spnC"
                     /protein_end="1227"
                     /protein_start="1196"
                     /score="38.2"
                     /tool="antismash"
                     /translation="LITGGLGAVGAQVARWLAEIGAERIVLTSRR"
     CDS_motif       39313..39342
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnC_0013"
                     /evalue="1.90E+00"
                     /label="PKSI-KR_m3"
                     /locus_tag="spnC"
                     /protein_end="1308"
                     /protein_start="1298"
                     /score="2.8"
                     /tool="antismash"
                     /translation="AKVRGAQVLD"
     CDS_motif       39364..39474
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnC_0014"
                     /evalue="2.90E-19"
                     /label="PKSI-KR_m4"
                     /locus_tag="spnC"
                     /protein_end="1352"
                     /protein_start="1315"
                     /score="61.7"
                     /tool="antismash"
                     /translation="LDAFVLFSSGAGVWGGGGQGAYGAANAFLDTLAEQRR"
     misc_feature    39790..40035
                     /gene="spnC"
                     /note="Region: ACP domain 3"
     aSDomain        39832..40047
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spnC_ACP.1"
                     /evalue="5.00E-32"
                     /label="spnC_ACP.1"
                     /locus_tag="spnC"
                     /protein_end="1543"
                     /protein_start="1471"
                     /score="101.9"
                     /tool="antismash"
                     /translation="DLVCAQVATVLGHGSREEVQPERAFRALGFDSLMAVDLRNRLTTA
                     TGLRLPTTTVFDYPNPAALAAHLLEEL"
     misc_feature    40102..41373
                     /gene="spnC"
                     /note="Region: ketosynthase domain 4"
     misc_feature    40102..44676
                     /gene="spnC"
                     /note="Region: extender module 4"
     aSDomain        40108..41382
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spnC_PKS_KS.2"
                     /domain_subtypes="Modular-KS"
                     /evalue="1.10E-184"
                     /label="spnC_PKS_KS.2"
                     /locus_tag="spnC"
                     /protein_end="1988"
                     /protein_start="1563"
                     /score="606.1"
                     /tool="antismash"
                     /translation="IAIVAMSCRFPGGAHSPEDLWRLVAAGTEVIGEFPSDRGWDAEGL
                     YDPDASRPGTTYARMAGFLYDAGEFDADLFGISPREALAMDPQQRLVLEIAWEALERAG
                     IDPLSLKGSGVGTYIGAGSRGYATDVRQFPEEAEGYLLTGTSASVLSGRVAYSFGFEGP
                     AVTVDTACSSSLVALHLACQSLRSGECDLALAGGVTVMSTPEMFVEFSRQRGLAPDGRC
                     KSFAESADGTGWGEGAGLLLLERLSDAHRNGHRVLAVVRGSAVNQDGASNGLAAPNGPS
                     QQRVINQALANAALSASDVDAVEAHGTGTRLGDPIEAQALIATYGQARERDRPLWLGSV
                     KSNIGHTQAAAGVAGVIKMVMAMRHGQLPASLHADEPTSEVDWSSGAVRLLAEQVPWPE
                     SDRVRRVGVSSFGISGTNAHVILEQA"
     aSModule        40108..44688
                     /complete
                     /domains="nrpspksdomains_spnC_PKS_KS.2"
                     /domains="nrpspksdomains_spnC_PKS_AT.2"
                     /domains="nrpspksdomains_spnC_PKS_KR.2"
                     /domains="nrpspksdomains_spnC_PKS_PP.1"
                     /locus_tags="spnC"
                     /monomer_pairings="mal -> ohmal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       40363..40389
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnC_0015"
                     /evalue="1.30E-01"
                     /label="PKSI-KS_m2"
                     /locus_tag="spnC"
                     /protein_end="1657"
                     /protein_start="1648"
                     /score="5.7"
                     /tool="antismash"
                     /translation="DPQQRLVLE"
     CDS_motif       40591..40638
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnC_0016"
                     /evalue="1.70E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="spnC"
                     /protein_end="1740"
                     /protein_start="1724"
                     /score="19.9"
                     /tool="antismash"
                     /translation="GPAVTVDTACSSSLVA"
     CDS_motif       40780..40818
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnC_0017"
                     /evalue="3.80E-01"
                     /label="PKSI-KS_m4"
                     /locus_tag="spnC"
                     /protein_end="1800"
                     /protein_start="1787"
                     /score="4.7"
                     /tool="antismash"
                     /translation="FAESADGTGWGEG"
     CDS_motif       40930..40953
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnC_0018"
                     /evalue="4.80E+01"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="spnC"
                     /protein_end="1845"
                     /protein_start="1837"
                     /score="-1.9"
                     /tool="antismash"
                     /translation="AAPNGPSQ"
     CDS_motif       41014..41058
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnC_0019"
                     /evalue="8.50E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="spnC"
                     /protein_end="1880"
                     /protein_start="1865"
                     /score="11.7"
                     /tool="antismash"
                     /translation="VEAHGTGTRLGDPIE"
     CDS_motif       41119..41163
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnC_0020"
                     /evalue="1.40E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="spnC"
                     /protein_end="1915"
                     /protein_start="1900"
                     /score="11.2"
                     /tool="antismash"
                     /translation="GSVKSNIGHTQAAAG"
     CDS_motif       41713..41766
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnC_0021"
                     /evalue="5.30E-06"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="spnC"
                     /protein_end="2116"
                     /protein_start="2098"
                     /score="18.8"
                     /tool="antismash"
                     /translation="FVFSGQGGQWLGMGRALY"
     misc_feature    41713..42705
                     /gene="spnC"
                     /note="Region: acyltransferase domain 4"
     aSDomain        41716..42612
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spnC_PKS_AT.2"
                     /evalue="2.50E-104"
                     /label="spnC_PKS_AT.2"
                     /locus_tag="spnC"
                     /protein_end="2398"
                     /protein_start="2099"
                     /score="340.7"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="VFSGQGGQWLGMGRALYSKFPVFAAAFDEACAELEAHLGEDRRVR
                     DVVFGSDAQLLDQTLWAQSGLFALQAGLLGLLGSWGVRPDVVMGHSVGELAAAFAAGVL
                     SLRDAARLVAARARLMQALPSDGAMLAVAAGEDLVRPLLAGREESVSVAALNAPGSVVL
                     SGDREVLASIVGRLTELRVRTRRLRVSHAFHSHRMDPMLGEFAQIAESAEFGKPTTPLV
                     STLTGELDRAAEMSTPGYWVRQAREPVRFADGVQALAAQGIGTVVELGPDGTLAALVRE
                     CATESDRVGRISSIPLMR"
     CDS_motif       41956..42078
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnC_0022"
                     /evalue="1.60E-22"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="spnC"
                     /protein_end="2220"
                     /protein_start="2179"
                     /score="71.7"
                     /tool="antismash"
                     /translation="GVRPDVVMGHSVGELAAAFAAGVLSLRDAARLVAARARLMQ"
     CDS_motif       42172..42210
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnC_0023"
                     /evalue="5.50E-02"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="spnC"
                     /protein_end="2264"
                     /protein_start="2251"
                     /score="7.1"
                     /tool="antismash"
                     /translation="AALNAPGSVVLSG"
     CDS_motif       42433..42468
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnC_0024"
                     /evalue="2.10E-04"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="spnC"
                     /protein_end="2350"
                     /protein_start="2338"
                     /score="14.7"
                     /tool="antismash"
                     /translation="YWVRQAREPVRF"
     CDS_motif       43021..43047
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnC_0025"
                     /evalue="1.40E+00"
                     /label="PKSI-KR_m3"
                     /locus_tag="spnC"
                     /protein_end="2543"
                     /protein_start="2534"
                     /score="3.2"
                     /tool="antismash"
                     /translation="PKISGTWLL"
     misc_feature    43615..44157
                     /gene="spnC"
                     /note="Region: ketoreductase domain 4"
     aSDomain        43621..44154
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spnC_PKS_KR.2"
                     /evalue="1.50E-60"
                     /label="spnC_PKS_KR.2"
                     /locus_tag="spnC"
                     /protein_end="2912"
                     /protein_start="2734"
                     /score="196.1"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: A1"
                     /tool="antismash"
                     /translation="GTVLVTGGTGGLGAHVARWLAGAGAEHVVLTSRRGADAPGAGELR
                     AELEALGARVSIVPCDVADRDAVAGVLAGIGGECPLTAVVHAAGVGEAGDVVEMGLADF
                     AAVLSAKVRGAANLDELLADSELDAFVMFSSVSGVWGAGGQGAYAAANAYLDALAEQRR
                     ARGLVGTAVAWGPWA"
     CDS_motif       43624..43722
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnC_0026"
                     /evalue="5.40E-14"
                     /label="PKSI-KR_m1"
                     /locus_tag="spnC"
                     /protein_end="2768"
                     /protein_start="2735"
                     /score="44.7"
                     /tool="antismash"
                     /translation="TVLVTGGTGGLGAHVARWLAGAGAEHVVLTSRR"
     CDS_motif       43948..43977
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnC_0027"
                     /evalue="7.10E-01"
                     /label="PKSI-KR_m3"
                     /locus_tag="spnC"
                     /protein_end="2853"
                     /protein_start="2843"
                     /score="4.0"
                     /tool="antismash"
                     /translation="AKVRGAANLD"
     CDS_motif       43999..44109
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnC_0028"
                     /evalue="1.60E-20"
                     /label="PKSI-KR_m4"
                     /locus_tag="spnC"
                     /protein_end="2897"
                     /protein_start="2860"
                     /score="65.6"
                     /tool="antismash"
                     /translation="LDAFVMFSSVSGVWGAGGQGAYAAANAYLDALAEQRR"
     misc_feature    44431..44676
                     /gene="spnC"
                     /note="Region: ACP domain 4"
     aSDomain        44431..44688
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spnC_PKS_PP.1"
                     /evalue="1.30E-29"
                     /label="spnC_PKS_PP.1"
                     /locus_tag="spnC"
                     /protein_end="3090"
                     /protein_start="3004"
                     /score="94.2"
                     /tool="antismash"
                     /translation="LAGLSRKERDDAVLDLVRAETAAVLGRDDATALAPSRPFQELGFD
                     SLMAVELRNRLNTATGIQLPASTIFDYPNAESLSRHLCAEL"
     aSDomain        44716..44922
                     /aSDomain="PKS_Docking_Cterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spnC_PKS_Docking_Cterm.1"
                     /evalue="4.40E-15"
                     /label="spnC_PKS_Docking_Cterm.1"
                     /locus_tag="spnC"
                     /protein_end="3168"
                     /protein_start="3099"
                     /score="48.2"
                     /tool="antismash"
                     /translation="ALAELDRIEQQLSMLTGEARARDRIATRLRALHEKWNSAAEVPTG
                     ADVLSTLDSATHDEIFEFIDNELD"
     gene            44966..59752
                     /gene="spnD"
     CDS             44966..59752
                     /NRPS_PKS="Domain: PKS_Docking_Nterm (7-35). E-value:
                     2.1e-14. Score: 44.6. Matches aSDomain:
                     nrpspksdomains_spnD_PKS_Docking_Nterm.1"
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (39-464). E-value:
                     1.8e-185. Score: 608.7. Matches aSDomain:
                     nrpspksdomains_spnD_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (576-872). E-value: 1.8e-104.
                     Score: 341.1. Matches aSDomain:
                     nrpspksdomains_spnD_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (941-1104). E-value: 1.1e-56.
                     Score: 183.6. Matches aSDomain:
                     nrpspksdomains_spnD_PKS_DH.1"
                     /NRPS_PKS="Domain: PKS_KR (1420-1599). E-value: 7e-63.
                     Score: 203.7. Matches aSDomain:
                     nrpspksdomains_spnD_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (1683-1765). E-value: 2.7e-29.
                     Score: 93.2. Matches aSDomain:
                     nrpspksdomains_spnD_PKS_PP.1"
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (1786-2212). E-value:
                     3.2e-184. Score: 604.6. Matches aSDomain:
                     nrpspksdomains_spnD_PKS_KS.2"
                     /NRPS_PKS="Domain: PKS_AT (2320-2619). E-value: 7.8e-104.
                     Score: 339.0. Matches aSDomain:
                     nrpspksdomains_spnD_PKS_AT.2"
                     /NRPS_PKS="Domain: PKS_KR (2954-3132). E-value: 8.8e-60.
                     Score: 193.6. Matches aSDomain:
                     nrpspksdomains_spnD_PKS_KR.2"
                     /NRPS_PKS="Domain: PKS_PP (3224-3310). E-value: 1.1e-31.
                     Score: 100.9. Matches aSDomain:
                     nrpspksdomains_spnD_PKS_PP.2"
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (3329-3753). E-value:
                     6.3e-185. Score: 606.9. Matches aSDomain:
                     nrpspksdomains_spnD_PKS_KS.3"
                     /NRPS_PKS="Domain: PKS_AT (3862-4160). E-value: 2.5e-105.
                     Score: 344.0. Matches aSDomain:
                     nrpspksdomains_spnD_PKS_AT.3"
                     /NRPS_PKS="Domain: PKS_KR (4494-4672). E-value: 1.7e-64.
                     Score: 208.9. Matches aSDomain:
                     nrpspksdomains_spnD_PKS_KR.3"
                     /NRPS_PKS="Domain: ACP (4774-4845). E-value: 4.4e-31.
                     Score: 98.9. Matches aSDomain: nrpspksdomains_spnD_ACP.1"
                     /NRPS_PKS="Domain: PKS_Docking_Cterm (4857-4926). E-value:
                     2.9e-15. Score: 48.7. Matches aSDomain:
                     nrpspksdomains_spnD_PKS_Docking_Cterm.1"
                     /codon_start=1
                     /gene="spnD"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     mod_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 304.4; E-value:
                     2.3e-92)"
                     /gene_kind="biosynthetic"
                     /note="involved in spinosyn aglycone biosynthesis"
                     /product="polyketide synthase extender modules 5-7"
                     /protein_id="AAG23263.1"
                     /sec_met_domain="mod_KS (E-value: 3.1e-234, bitscore:
                     768.0, seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.8e-15, bitscore:
                     47.3, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 1e-105, bitscore: 344.0,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 2.1e-63, bitscore:
                     204.0, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEITMANEEKLFGYLKKVTADLHQTRQRLLAAESRSQEPIAIVSA
                     SCRLPGGVDSPEALWQLVRTGTDAISEFPADRGWDLGRLYDPDPNHQGTSYTRAGGFLA
                     GAGDFDPAMFGISPREALAMDPQQRLLLELSWEALERAGIDPTSLRGSKTGVFGGVTPQ
                     EYGPSLQEMSRNAGGFGLTGRMVSVASGRVAYSFGFEGPAVTVDTACSSSLVALHLACQ
                     SLRSGECDLALAGGVTVMATPATFVEFSRQRGLAPDGRCKSFAAAADGTGWGEGAGLVL
                     LERLSDARRNGHEVLAVVRGSAVNQDGASNGLTAPNGPSQQRVITQALASAGLSVSDVD
                     AVEAHGTGTTLGDPIEAQALIATYGQGREKDRPLWLGSVKSNIGHTQAAAGVAGVIKMV
                     LAMRHGQLPATLHVDEPTSAVDWSAGSVRLLTENTPWPDSGRPCRVGVSSFGISGTNAH
                     VILEQSPVEQGEPAGPVEGEREPDVAVPVVPWVLSGKTPEAARAQAERVHSHIEDRPGL
                     SPVDVAYSLGMTRAALDERAVVLGSDRAALLTGLRAFADGCDAPEVVSGSVGLGGRVGF
                     VFSGQGGQWPGMGRGLYSVFPVFADAFDEACAELDAHLGQELRVRDVVFGSQAWLLDRT
                     VWAQSGLFALQIGLLRLLGSWGVRPDVVLGHSVGELAAVHAAGVLSLSEAARLVAGRAR
                     LMQALPSGGAMLAVATGEFQVDPLLDGVRDRIGIAAVNGPESVVLSGDRELLTEIADRL
                     HDQGCRTRWLRVSHAFHSPHMEPMLEEFAQISRGREYHAPELPIISTLIGELDGGRVMG
                     TPEYWVRQVREPVRFAEGVQALVGQGVGTIVELGPDGALSTLVEECVAESGRVAGIPLM
                     RKDRDEARTVLAALAQIHTRGGEVDWRSFFAGTGAKQVDLPTYAFQRQRYWLASTGRAG
                     DVTAAGLAEADHPLLGAVVALADGEGVVLTGRLTAGSHPWLSDHRVLGEIVVPGTAIVE
                     LVWHVGERLGCGRVEELALEAPLILPDHGAVQVQVLVGPPGESGARSVALYSCPGEAIE
                     PEWKKHATGVLLPPVAAENHELTAWPPENATEIDADGVYAFLEGHGFAYGPAFRCLRGA
                     WRRGGEVFAEVALPDDMQAGVDRFGVHPALLDAVLHAAAAETSVVQSEARVPFSWRGVE
                     LRATESAVVRARLSLTSDDELSLVAVDPAGRFVATVDSLVTRPISRQQVRSGAIGDCLF
                     EVEWHRKALLGTTAGDDLAIVGDGPSWPESVRATARFATLDEFRAAVDSDVPAPGSVLV
                     AAMSAEEVEGGSLPSRAQESTSDLLALVQSWLADERFAESQLVVVTRAAVSADSDSDVA
                     DLVGASSWGLLSSAQSENPGRFVLVDVDGTPESWQALPAAVRAGEPQLALRRGVALVPR
                     LARLTVREEGSSPQLDTDGTVLITGGTGALGGVVARHLVEEHGIRRLVLAGRRGWNAPG
                     VHELVDELARAGAVVEVVACDVADRTDLEHVLAAIPVDWPLRGIVHTAGVLADGVIGSL
                     SAADVGTVFAPKVTGAWHLHELTRDLDLSFFVLFSSFSGIAGAAGQANYAAANTFLDAL
                     ARYRRARGLPGLSLAWGLWAQPSGMTSGLDAASVERLARTGIAELSTEDGLRLFDAAFA
                     KDRACVVAARLDRALLVGNGRSHAIPALLSALVPVRGGVARKTANSQAADEDALLGLVR
                     EHVSAVLGYSGAVEVGGDRAFRDLGFDSLSGVELRNRLAGVLGVRLPATAVFDYPTPRA
                     LARFLHQELAGEVASTSTPVTRAASAEEDLVAIVGMGCRFPGGVSSPEELWRLVAGGVD
                     AVAGFPDDRGWDLAALYDPDPDRLGTSYVCEGGFLRDAAEFDADMFGISPREALAMDPQ
                     QRLLLEVAWETLERAGIDPFSLHGSRTGVFAGLMYHDYGARFITRAPEGFEGHLGTGNA
                     GSVLSGRVAYSFGFEGPAVTVDTACSSSLVALHLAGQALRAGECEFALAGGVTVMSTPT
                     TFVEFSRQRGLAPDGRCKSFAAAADGTGWGEGAGLVLLERLSDARRNGHEVLAVVRGSA
                     VNQDGASNGLTAPNGPSQQRVITQALTSAGLSVSDVDAVEAHGTGTRLGDPIEAQALIA
                     TYGRDRDPGRPLWLGSVKSNIGHTQAAAGVAGVIKMVMAMRQGELPRTLHVDEPSAQVD
                     WSAGTVQLLTENTPWPDSGRLRRAGVSSFGISGTNAHLILEQPPRESQRSTEPDSGSVR
                     DFPVVPWMVSGKTPEALSAQADALMSYLSNRVDASPRDIGYSLAVTRPALDHRAVVLGA
                     DRAALLPGLKALAVSNDAAEVITGTRAAGPVGFVFSGQGGQWPGMGSGLHSAFPVFADA
                     FDEACCELDAHLGQMARLRDVLSGSDTQLLDQTLWAQPGLFALQVGLWELLGSWGVRPA
                     VVLGHSVGELAAAFAAGVLSLRDAARLVAGRARLMQALPTGGAMLAAAAGEEQLRPLLA
                     DCGDRVGIAAVNAPGSVVLSGDRDVLDDIAGRLDGQGIRSRWLRVSHAFHSHRMDPMLA
                     EFTEIARSVDYRSSGLPIVSTLTGELDEVGMPATPEYWVRQVREPVRFADGVAALAAHG
                     VSTVVEVGPDGVLSALVQECAAGSDQGGRVAAVPLMRSNRDEAHTVTTALAQIHVRGAE
                     VDWRSFFAGTGAKQVELPTYAFQRQRYWLDSPSEPVGQSADPARQSGFWELVEQEDVSA
                     LSAALHITGDHDVQASLESVVPVLSSWHRRIRNESLVHQWRYRISWHERADLPDPSLSG
                     TWLVVVPEGWSASRQVLRFNEMFEERGCPAVLFELAGHDEEALAQRFRSLPVASGGISG
                     VLSLLALDESPSSPNAALPNGALNSLVLLRALRAADVSAPLWLATCGGVAVGDVPVNPG
                     QALVWGLGRVVGLEHPAWWGGLVDVPCLLDEDARERLSVVLAGLGEDEIAVRPGGVFVR
                     RLERAGAASGAGSVWRPRGTVLVTGGTGGLGAHVARWLAGAGAEHVVLTSRRGAAAPGA
                     GDLRAELEALGARVSITACDVADRDALAEVLATIPDDCPLTAVMHAAGVVEVGDVASMC
                     LTDFVGVLSAKAGGAANLDELLADVELDAFVLFSSVSGVWGAGGQGAYAAANAYLDALA
                     QQRRARGLVGTAVAWGPWAGDGMAAGEGGAQLRRAGLVPMAADRALLALQGALDRDETS
                     LVVADMAWERFAPVFAMSRRRPLLDELPEAQQALADAENTTDAADSAVPLPRLAGMAAA
                     ERRRAMLDLVLAEASIVLGHNGSDPVGPDRAFQELGFDSLMAVELRNRLGEATGLSLPA
                     TLIFDYPSPSALAEQLVGELVGAQPATTVVAGADPVDDPVVVVAMGCRYPGDVCSPEEL
                     WQLVSAGRDAVSTFPVDRGWDCNTLFDPDPDRAGSTYVREGAFLTGADRFDAGFFGISP
                     REARAMDPQQRLLLEVAWEVFERAGIAPLSLRGSRTGVFAGTNGQDHGAKVAAAPEAAG
                     HLLTGNAASVLAGRLSYTFGLEGPAVAVDTACSSSLVALHLACQSLRSGECDMALAGGV
                     TVMSTPLAFLEFSRQRGLAPDGRCKSFAAAADGTGWGEGAGLVLLERLSDARRNGHRVL
                     AVVRGSAVNQDGASNGLTAPNGPSQQRVIRQALANAGLSASDVDVVEAHGTGTGLGDPI
                     EAQALIATYGQERDPERALWLGSIKSNIGHTQAAAGVAGVIKMVQAMRHGELPATLHVD
                     KPTPQVDWSAGAVRLLTGNTPWPESGRPRRAGVSSFGISGTNAHLILEQPPSEPAEIDQ
                     SDRRVTAHPAVIPWMLSARSLAALQAQAAALQARLDRGPGASPLDLGYSLATTRSVLDE
                     RAVVWGADREALLSRLAALADGRTAPGVITGSANSGGRIGFVFSGQGSQWLGMGKALCA
                     AFPAFADAFEEACDALSAHLGADVRGVLFGADEQMLDRTLWAQSGIFAVQVGLLGLLRS
                     WGVRPAAVLGHSVGELAAAHAAGVLSLPDAARLVAARAHLMQALPTGGAMLAVATSEAA
                     VGPLLSGVCDRVSIAAINGPESVVLSGDRDVLVELAGEFDARGLRTKWLRVSHAFHSHR
                     MEPILDEYAETARCVEFGEPVVPIVSAATGALDTTGLMCAADYWTRQVRDPVRFGDGVR
                     ALVGQGVDTIVEFGPDGALSALVEQCLAGSDQAGRVAAIPLMRRDRDEVETAVAALAHV
                     HVRGGAVDWSACFAGTGARTVELPTYAFQRQRYWLAGQADGRGGDVVADPVDARFWELV
                     ERADPEPLVDELCIDRDQPFREVLPVLASWREKQRQEALADSWRYQVRWRSVEVPSAAA
                     LRGVWLVVLPADVPRDQPAVVIDALIARGAEVAVLELTEQDLQRSALVDKVRAVIADRT
                     EVTGVLSLLAMDGMPCAAHPHLSRGVAATVILTQVLGDAGVSAPLWLATTGGVEAGTED
                     GPADPDHGLIWGLGRVVGLEHPQWWGGLIDLPETLDETSRNGLVAALAGTAAEDQLAVR
                     SSGLFVRRVVRAARNPRSETWRSRGTVLITGGTGALGAEVARWLARRGAEHLVLISRRG
                     PEAPGAADLGAELTELGVKVTVLACDVTDRDELAAVLAAVPTEYPLSAVVHTAGVGTPA
                     NLAETTLAQFADVLSAKVVGAANLDRLLGGQPLDAFVLFSSISGVWGAGGQGAYSAANA
                     YLDALAERRRACGRPATCIAWGPWAGAGMAVQEGNEAHLRRRGLVPMEPQSALFALQQA
                     LSQRETAITVADVDWERFAASFTAARPRPLLEEIVDLRPDTETEEKHGAGELGQQLAAL
                     PPAERGHLLLEVVLAETASTLGHDSAEAVQPDRTFAELGFDSLTAVELRNRLNAVTGLR
                     LPPTLVFDHPTPLALSEQLVPALVAEPDNGIESLLAELDRLDTTLAQGPSIPLEDQAKV
                     AERLHALLAKWDGARDGTARATSPQSLTAATDDEIFDLIDRKFRR"
     aSDomain        44987..45070
                     /aSDomain="PKS_Docking_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spnD_PKS_Docking_Nterm.1"
                     /evalue="2.10E-14"
                     /label="spnD_PKS_Docking_Nterm.1"
                     /locus_tag="spnD"
                     /protein_end="35"
                     /protein_start="7"
                     /score="44.6"
                     /tool="antismash"
                     /translation="EEKLFGYLKKVTADLHQTRQRLLAAESR"
     misc_feature    45077..46348
                     /gene="spnD"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="Region: ketosynthase domain 5"
     misc_feature    45077..50254
                     /gene="spnD"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="Region: extender module 5"
     aSDomain        45083..46357
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spnD_PKS_KS.1"
                     /domain_subtypes="Modular-KS"
                     /evalue="1.80E-185"
                     /label="spnD_PKS_KS.1"
                     /locus_tag="spnD"
                     /protein_end="464"
                     /protein_start="39"
                     /score="608.7"
                     /tool="antismash"
                     /translation="IAIVSASCRLPGGVDSPEALWQLVRTGTDAISEFPADRGWDLGRL
                     YDPDPNHQGTSYTRAGGFLAGAGDFDPAMFGISPREALAMDPQQRLLLELSWEALERAG
                     IDPTSLRGSKTGVFGGVTPQEYGPSLQEMSRNAGGFGLTGRMVSVASGRVAYSFGFEGP
                     AVTVDTACSSSLVALHLACQSLRSGECDLALAGGVTVMATPATFVEFSRQRGLAPDGRC
                     KSFAAAADGTGWGEGAGLVLLERLSDARRNGHEVLAVVRGSAVNQDGASNGLTAPNGPS
                     QQRVITQALASAGLSVSDVDAVEAHGTGTTLGDPIEAQALIATYGQGREKDRPLWLGSV
                     KSNIGHTQAAAGVAGVIKMVLAMRHGQLPATLHVDEPTSAVDWSAGSVRLLTENTPWPD
                     SGRPCRVGVSSFGISGTNAHVILEQS"
     aSModule        45083..50260
                     /complete
                     /domains="nrpspksdomains_spnD_PKS_KS.1"
                     /domains="nrpspksdomains_spnD_PKS_AT.1"
                     /domains="nrpspksdomains_spnD_PKS_DH.1"
                     /domains="nrpspksdomains_spnD_PKS_KR.1"
                     /domains="nrpspksdomains_spnD_PKS_PP.1"
                     /locus_tags="spnD"
                     /monomer_pairings="mal -> ccmal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       45338..45364
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnD_0001"
                     /evalue="9.90E-02"
                     /label="PKSI-KS_m2"
                     /locus_tag="spnD"
                     /protein_end="133"
                     /protein_start="124"
                     /score="6.1"
                     /tool="antismash"
                     /translation="DPQQRLLLE"
     CDS_motif       45566..45613
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnD_0002"
                     /evalue="2.80E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="spnD"
                     /protein_end="216"
                     /protein_start="200"
                     /score="19.3"
                     /tool="antismash"
                     /translation="GPAVTVDTACSSSLVA"
     CDS_motif       45989..46033
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnD_0003"
                     /evalue="1.80E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="spnD"
                     /protein_end="356"
                     /protein_start="341"
                     /score="10.9"
                     /tool="antismash"
                     /translation="VEAHGTGTTLGDPIE"
     CDS_motif       46094..46138
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnD_0004"
                     /evalue="2.40E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="spnD"
                     /protein_end="391"
                     /protein_start="376"
                     /score="10.6"
                     /tool="antismash"
                     /translation="GSVKSNIGHTQAAAG"
     CDS_motif       46691..46744
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnD_0005"
                     /evalue="1.60E-05"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="spnD"
                     /protein_end="593"
                     /protein_start="575"
                     /score="17.3"
                     /tool="antismash"
                     /translation="FVFSGQGGQWPGMGRGLY"
     misc_feature    46691..47674
                     /gene="spnD"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="Region: acyltransferase domain 5"
     aSDomain        46694..47581
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spnD_PKS_AT.1"
                     /evalue="1.80E-104"
                     /label="spnD_PKS_AT.1"
                     /locus_tag="spnD"
                     /protein_end="872"
                     /protein_start="576"
                     /score="341.1"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="VFSGQGGQWPGMGRGLYSVFPVFADAFDEACAELDAHLGQELRVR
                     DVVFGSQAWLLDRTVWAQSGLFALQIGLLRLLGSWGVRPDVVLGHSVGELAAVHAAGVL
                     SLSEAARLVAGRARLMQALPSGGAMLAVATGEFQVDPLLDGVRDRIGIAAVNGPESVVL
                     SGDRELLTEIADRLHDQGCRTRWLRVSHAFHSPHMEPMLEEFAQISRGREYHAPELPII
                     STLIGELDGGRVMGTPEYWVRQVREPVRFAEGVQALVGQGVGTIVELGPDGALSTLVEE
                     CVAESGRVAGIPLMR"
     CDS_motif       46934..47056
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnD_0006"
                     /evalue="1.30E-19"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="spnD"
                     /protein_end="697"
                     /protein_start="656"
                     /score="62.4"
                     /tool="antismash"
                     /translation="GVRPDVVLGHSVGELAAVHAAGVLSLSEAARLVAGRARLMQ"
     CDS_motif       47150..47188
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnD_0007"
                     /evalue="1.20E-03"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="spnD"
                     /protein_end="741"
                     /protein_start="728"
                     /score="12.1"
                     /tool="antismash"
                     /translation="AAVNGPESVVLSG"
     CDS_motif       47252..47278
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnD_0008"
                     /evalue="1.10E-01"
                     /label="PKSI-AT-M_m6"
                     /locus_tag="spnD"
                     /protein_end="771"
                     /protein_start="762"
                     /score="6.1"
                     /tool="antismash"
                     /translation="LRVSHAFHS"
     CDS_motif       47411..47446
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnD_0009"
                     /evalue="1.70E-04"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="spnD"
                     /protein_end="827"
                     /protein_start="815"
                     /score="14.9"
                     /tool="antismash"
                     /translation="YWVRQVREPVRF"
     misc_feature    47753..48310
                     /gene="spnD"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="Region: dehydratase domain 5"
     aSDomain        47789..48277
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spnD_PKS_DH.1"
                     /evalue="1.10E-56"
                     /label="spnD_PKS_DH.1"
                     /locus_tag="spnD"
                     /protein_end="1104"
                     /protein_start="941"
                     /score="183.6"
                     /tool="antismash"
                     /translation="HPLLGAVVALADGEGVVLTGRLTAGSHPWLSDHRVLGEIVVPGTA
                     IVELVWHVGERLGCGRVEELALEAPLILPDHGAVQVQVLVGPPGESGARSVALYSCPGE
                     AIEPEWKKHATGVLLPPVAAENHELTAWPPENATEIDADGVYAFLEGHGFAYGPAFRCL
                     "
     CDS_motif       47873..47941
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnD_0010"
                     /evalue="9.90E-08"
                     /label="PKSI-DH_m2"
                     /locus_tag="spnD"
                     /protein_end="992"
                     /protein_start="969"
                     /score="24.5"
                     /tool="antismash"
                     /translation="WLSDHRVLGEIVVPGTAIVELVW"
     aSDomain        49226..49762
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spnD_PKS_KR.1"
                     /evalue="7.00E-63"
                     /label="spnD_PKS_KR.1"
                     /locus_tag="spnD"
                     /protein_end="1599"
                     /protein_start="1420"
                     /score="203.7"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="GTVLITGGTGALGGVVARHLVEEHGIRRLVLAGRRGWNAPGVHEL
                     VDELARAGAVVEVVACDVADRTDLEHVLAAIPVDWPLRGIVHTAGVLADGVIGSLSAAD
                     VGTVFAPKVTGAWHLHELTRDLDLSFFVLFSSFSGIAGAAGQANYAAANTFLDALARYR
                     RARGLPGLSLAWGLWA"
     misc_feature    49226..49771
                     /gene="spnD"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="Region: ketoreductase domain 5"
     CDS_motif       49229..49330
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnD_0011"
                     /evalue="1.10E-08"
                     /label="PKSI-KR_m1"
                     /locus_tag="spnD"
                     /protein_end="1455"
                     /protein_start="1421"
                     /score="27.6"
                     /tool="antismash"
                     /translation="TVLITGGTGALGGVVARHLVEEHGIRRLVLAGRR"
     CDS_motif       49556..49585
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnD_0012"
                     /evalue="6.20E-03"
                     /label="PKSI-KR_m3"
                     /locus_tag="spnD"
                     /protein_end="1540"
                     /protein_start="1530"
                     /score="10.1"
                     /tool="antismash"
                     /translation="PKVTGAWHLH"
     CDS_motif       49607..49717
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnD_0013"
                     /evalue="5.10E-20"
                     /label="PKSI-KR_m4"
                     /locus_tag="spnD"
                     /protein_end="1584"
                     /protein_start="1547"
                     /score="64.1"
                     /tool="antismash"
                     /translation="LSFFVLFSSFSGIAGAAGQANYAAANTFLDALARYRR"
     misc_feature    50009..50254
                     /gene="spnD"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="Region: ACP domain 5"
     aSDomain        50015..50260
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spnD_PKS_PP.1"
                     /evalue="2.70E-29"
                     /label="spnD_PKS_PP.1"
                     /locus_tag="spnD"
                     /protein_end="1765"
                     /protein_start="1683"
                     /score="93.2"
                     /tool="antismash"
                     /translation="SQAADEDALLGLVREHVSAVLGYSGAVEVGGDRAFRDLGFDSLSG
                     VELRNRLAGVLGVRLPATAVFDYPTPRALARFLHQEL"
     misc_feature    50318..51592
                     /gene="spnD"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="Region: ketosynthase domain 6"
     misc_feature    50318..54883
                     /gene="spnD"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="Region: extender module 6"
     aSDomain        50324..51601
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spnD_PKS_KS.2"
                     /domain_subtypes="Modular-KS"
                     /evalue="3.20E-184"
                     /label="spnD_PKS_KS.2"
                     /locus_tag="spnD"
                     /protein_end="2212"
                     /protein_start="1786"
                     /score="604.6"
                     /tool="antismash"
                     /translation="VAIVGMGCRFPGGVSSPEELWRLVAGGVDAVAGFPDDRGWDLAAL
                     YDPDPDRLGTSYVCEGGFLRDAAEFDADMFGISPREALAMDPQQRLLLEVAWETLERAG
                     IDPFSLHGSRTGVFAGLMYHDYGARFITRAPEGFEGHLGTGNAGSVLSGRVAYSFGFEG
                     PAVTVDTACSSSLVALHLAGQALRAGECEFALAGGVTVMSTPTTFVEFSRQRGLAPDGR
                     CKSFAAAADGTGWGEGAGLVLLERLSDARRNGHEVLAVVRGSAVNQDGASNGLTAPNGP
                     SQQRVITQALTSAGLSVSDVDAVEAHGTGTRLGDPIEAQALIATYGRDRDPGRPLWLGS
                     VKSNIGHTQAAAGVAGVIKMVMAMRQGELPRTLHVDEPSAQVDWSAGTVQLLTENTPWP
                     DSGRLRRAGVSSFGISGTNAHLILEQP"
     aSModule        50324..54895
                     /complete
                     /domains="nrpspksdomains_spnD_PKS_KS.2"
                     /domains="nrpspksdomains_spnD_PKS_AT.2"
                     /domains="nrpspksdomains_spnD_PKS_KR.2"
                     /domains="nrpspksdomains_spnD_PKS_PP.2"
                     /locus_tags="spnD"
                     /monomer_pairings="mal -> ohmal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       50579..50605
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnD_0014"
                     /evalue="9.90E-02"
                     /label="PKSI-KS_m2"
                     /locus_tag="spnD"
                     /protein_end="1880"
                     /protein_start="1871"
                     /score="6.1"
                     /tool="antismash"
                     /translation="DPQQRLLLE"
     CDS_motif       50810..50857
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnD_0015"
                     /evalue="2.80E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="spnD"
                     /protein_end="1964"
                     /protein_start="1948"
                     /score="19.3"
                     /tool="antismash"
                     /translation="GPAVTVDTACSSSLVA"
     misc_feature    50858..50860
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     CDS_motif       51233..51277
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnD_0016"
                     /evalue="1.50E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="spnD"
                     /protein_end="2104"
                     /protein_start="2089"
                     /score="11.1"
                     /tool="antismash"
                     /translation="VEAHGTGTRLGDPIE"
     CDS_motif       51338..51382
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnD_0017"
                     /evalue="2.40E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="spnD"
                     /protein_end="2139"
                     /protein_start="2124"
                     /score="10.6"
                     /tool="antismash"
                     /translation="GSVKSNIGHTQAAAG"
     CDS_motif       51923..51973
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnD_0018"
                     /evalue="6.90E-05"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="spnD"
                     /protein_end="2336"
                     /protein_start="2319"
                     /score="15.4"
                     /tool="antismash"
                     /translation="FVFSGQGGQWPGMGSGL"
     misc_feature    51923..52915
                     /gene="spnD"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="Region: acyltransferase domain 6"
     aSDomain        51926..52822
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spnD_PKS_AT.2"
                     /evalue="7.80E-104"
                     /label="spnD_PKS_AT.2"
                     /locus_tag="spnD"
                     /protein_end="2619"
                     /protein_start="2320"
                     /score="339.0"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="VFSGQGGQWPGMGSGLHSAFPVFADAFDEACCELDAHLGQMARLR
                     DVLSGSDTQLLDQTLWAQPGLFALQVGLWELLGSWGVRPAVVLGHSVGELAAAFAAGVL
                     SLRDAARLVAGRARLMQALPTGGAMLAAAAGEEQLRPLLADCGDRVGIAAVNAPGSVVL
                     SGDRDVLDDIAGRLDGQGIRSRWLRVSHAFHSHRMDPMLAEFTEIARSVDYRSSGLPIV
                     STLTGELDEVGMPATPEYWVRQVREPVRFADGVAALAAHGVSTVVEVGPDGVLSALVQE
                     CAAGSDQGGRVAAVPLMR"
     CDS_motif       52166..52288
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnD_0019"
                     /evalue="2.10E-20"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="spnD"
                     /protein_end="2441"
                     /protein_start="2400"
                     /score="64.9"
                     /tool="antismash"
                     /translation="GVRPAVVLGHSVGELAAAFAAGVLSLRDAARLVAGRARLMQ"
     CDS_motif       52382..52420
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnD_0020"
                     /evalue="4.10E-02"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="spnD"
                     /protein_end="2485"
                     /protein_start="2472"
                     /score="7.5"
                     /tool="antismash"
                     /translation="AAVNAPGSVVLSG"
     CDS_motif       52484..52510
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnD_0021"
                     /evalue="1.10E-01"
                     /label="PKSI-AT-M_m6"
                     /locus_tag="spnD"
                     /protein_end="2515"
                     /protein_start="2506"
                     /score="6.1"
                     /tool="antismash"
                     /translation="LRVSHAFHS"
     CDS_motif       52643..52678
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnD_0022"
                     /evalue="1.70E-04"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="spnD"
                     /protein_end="2571"
                     /protein_start="2559"
                     /score="14.9"
                     /tool="antismash"
                     /translation="YWVRQVREPVRF"
     misc_feature    53822..54361
                     /gene="spnD"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="Region: ketoreductase domain 6"
     aSDomain        53828..54361
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spnD_PKS_KR.2"
                     /evalue="8.80E-60"
                     /label="spnD_PKS_KR.2"
                     /locus_tag="spnD"
                     /protein_end="3132"
                     /protein_start="2954"
                     /score="193.6"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: A1"
                     /tool="antismash"
                     /translation="GTVLVTGGTGGLGAHVARWLAGAGAEHVVLTSRRGAAAPGAGDLR
                     AELEALGARVSITACDVADRDALAEVLATIPDDCPLTAVMHAAGVVEVGDVASMCLTDF
                     VGVLSAKAGGAANLDELLADVELDAFVLFSSVSGVWGAGGQGAYAAANAYLDALAQQRR
                     ARGLVGTAVAWGPWA"
     CDS_motif       53831..53929
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnD_0023"
                     /evalue="8.60E-14"
                     /label="PKSI-KR_m1"
                     /locus_tag="spnD"
                     /protein_end="2988"
                     /protein_start="2955"
                     /score="44.0"
                     /tool="antismash"
                     /translation="TVLVTGGTGGLGAHVARWLAGAGAEHVVLTSRR"
     CDS_motif       54155..54184
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnD_0024"
                     /evalue="2.90E+01"
                     /label="PKSI-KR_m3"
                     /locus_tag="spnD"
                     /protein_end="3073"
                     /protein_start="3063"
                     /score="-0.7"
                     /tool="antismash"
                     /translation="AKAGGAANLD"
     CDS_motif       54206..54316
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnD_0025"
                     /evalue="8.10E-20"
                     /label="PKSI-KR_m4"
                     /locus_tag="spnD"
                     /protein_end="3117"
                     /protein_start="3080"
                     /score="63.4"
                     /tool="antismash"
                     /translation="LDAFVLFSSVSGVWGAGGQGAYAAANAYLDALAQQRR"
     misc_feature    54638..54883
                     /gene="spnD"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="Region: ACP domain 6"
     aSDomain        54638..54895
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spnD_PKS_PP.2"
                     /evalue="1.10E-31"
                     /label="spnD_PKS_PP.2"
                     /locus_tag="spnD"
                     /protein_end="3310"
                     /protein_start="3224"
                     /score="100.9"
                     /tool="antismash"
                     /translation="LAGMAAAERRRAMLDLVLAEASIVLGHNGSDPVGPDRAFQELGFD
                     SLMAVELRNRLGEATGLSLPATLIFDYPSPSALAEQLVGEL"
     CDS_motif       54911..54970
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnD_0026"
                     /evalue="5.90E+00"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="spnD"
                     /protein_end="3335"
                     /protein_start="3315"
                     /score="0.2"
                     /tool="antismash"
                     /translation="ATTVVAGADPVDDPVVVVAM"
     misc_feature    54947..56215
                     /gene="spnD"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="Region: ketosynthase domain 7"
     misc_feature    54947..59494
                     /gene="spnD"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="Region: extender module 7"
     aSDomain        54953..56224
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spnD_PKS_KS.3"
                     /domain_subtypes="Modular-KS"
                     /evalue="6.30E-185"
                     /label="spnD_PKS_KS.3"
                     /locus_tag="spnD"
                     /protein_end="3753"
                     /protein_start="3329"
                     /score="606.9"
                     /tool="antismash"
                     /translation="VVVVAMGCRYPGDVCSPEELWQLVSAGRDAVSTFPVDRGWDCNTL
                     FDPDPDRAGSTYVREGAFLTGADRFDAGFFGISPREARAMDPQQRLLLEVAWEVFERAG
                     IAPLSLRGSRTGVFAGTNGQDHGAKVAAAPEAAGHLLTGNAASVLAGRLSYTFGLEGPA
                     VAVDTACSSSLVALHLACQSLRSGECDMALAGGVTVMSTPLAFLEFSRQRGLAPDGRCK
                     SFAAAADGTGWGEGAGLVLLERLSDARRNGHRVLAVVRGSAVNQDGASNGLTAPNGPSQ
                     QRVIRQALANAGLSASDVDVVEAHGTGTGLGDPIEAQALIATYGQERDPERALWLGSIK
                     SNIGHTQAAAGVAGVIKMVQAMRHGELPATLHVDKPTPQVDWSAGAVRLLTGNTPWPES
                     GRPRRAGVSSFGISGTNAHLILEQP"
     aSModule        54953..59500
                     /complete
                     /domains="nrpspksdomains_spnD_PKS_KS.3"
                     /domains="nrpspksdomains_spnD_PKS_AT.3"
                     /domains="nrpspksdomains_spnD_PKS_KR.3"
                     /domains="nrpspksdomains_spnD_ACP.1"
                     /locus_tags="spnD"
                     /monomer_pairings="mal -> ohmal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       55208..55234
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnD_0027"
                     /evalue="9.90E-02"
                     /label="PKSI-KS_m2"
                     /locus_tag="spnD"
                     /protein_end="3423"
                     /protein_start="3414"
                     /score="6.1"
                     /tool="antismash"
                     /translation="DPQQRLLLE"
     CDS_motif       55433..55480
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnD_0028"
                     /evalue="6.50E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="spnD"
                     /protein_end="3505"
                     /protein_start="3489"
                     /score="18.2"
                     /tool="antismash"
                     /translation="GPAVAVDTACSSSLVA"
     CDS_motif       55856..55900
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnD_0029"
                     /evalue="3.60E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="spnD"
                     /protein_end="3645"
                     /protein_start="3630"
                     /score="10.1"
                     /tool="antismash"
                     /translation="VEAHGTGTGLGDPIE"
     CDS_motif       55961..56005
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnD_0030"
                     /evalue="3.70E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="spnD"
                     /protein_end="3680"
                     /protein_start="3665"
                     /score="10.1"
                     /tool="antismash"
                     /translation="GSIKSNIGHTQAAAG"
     CDS_motif       56549..56599
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnD_0031"
                     /evalue="3.40E-06"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="spnD"
                     /protein_end="3878"
                     /protein_start="3861"
                     /score="19.3"
                     /tool="antismash"
                     /translation="FVFSGQGSQWLGMGKAL"
     misc_feature    56549..57535
                     /gene="spnD"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="Region: acyltransferase domain 7"
     aSDomain        56552..57445
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spnD_PKS_AT.3"
                     /evalue="2.50E-105"
                     /label="spnD_PKS_AT.3"
                     /locus_tag="spnD"
                     /protein_end="4160"
                     /protein_start="3862"
                     /score="344.0"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="VFSGQGSQWLGMGKALCAAFPAFADAFEEACDALSAHLGADVRGV
                     LFGADEQMLDRTLWAQSGIFAVQVGLLGLLRSWGVRPAAVLGHSVGELAAAHAAGVLSL
                     PDAARLVAARAHLMQALPTGGAMLAVATSEAAVGPLLSGVCDRVSIAAINGPESVVLSG
                     DRDVLVELAGEFDARGLRTKWLRVSHAFHSHRMEPILDEYAETARCVEFGEPVVPIVSA
                     ATGALDTTGLMCAADYWTRQVRDPVRFGDGVRALVGQGVDTIVEFGPDGALSALVEQCL
                     AGSDQAGRVAAIPLMRR"
     CDS_motif       56786..56908
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnD_0032"
                     /evalue="1.20E-21"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="spnD"
                     /protein_end="3981"
                     /protein_start="3940"
                     /score="69.0"
                     /tool="antismash"
                     /translation="GVRPAAVLGHSVGELAAAHAAGVLSLPDAARLVAARAHLMQ"
     CDS_motif       57002..57040
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnD_0033"
                     /evalue="9.50E-04"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="spnD"
                     /protein_end="4025"
                     /protein_start="4012"
                     /score="12.5"
                     /tool="antismash"
                     /translation="AAINGPESVVLSG"
     CDS_motif       57104..57130
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnD_0034"
                     /evalue="1.10E-01"
                     /label="PKSI-AT-M_m6"
                     /locus_tag="spnD"
                     /protein_end="4055"
                     /protein_start="4046"
                     /score="6.1"
                     /tool="antismash"
                     /translation="LRVSHAFHS"
     CDS_motif       57263..57298
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnD_0035"
                     /evalue="7.30E-04"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="spnD"
                     /protein_end="4111"
                     /protein_start="4099"
                     /score="13.0"
                     /tool="antismash"
                     /translation="YWTRQVRDPVRF"
     CDS_motif       58106..58174
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnD_0036"
                     /evalue="3.30E+01"
                     /label="PKSI-KR_m1"
                     /locus_tag="spnD"
                     /protein_end="4403"
                     /protein_start="4380"
                     /score="-2.7"
                     /tool="antismash"
                     /translation="TVILTQVLGDAGVSAPLWLATTG"
     misc_feature    58106..58990
                     /gene="spnD"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="Region: ketoreductase domain 7"
     aSDomain        58448..58981
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spnD_PKS_KR.3"
                     /evalue="1.70E-64"
                     /label="spnD_PKS_KR.3"
                     /locus_tag="spnD"
                     /protein_end="4672"
                     /protein_start="4494"
                     /score="208.9"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: A1"
                     /tool="antismash"
                     /translation="GTVLITGGTGALGAEVARWLARRGAEHLVLISRRGPEAPGAADLG
                     AELTELGVKVTVLACDVTDRDELAAVLAAVPTEYPLSAVVHTAGVGTPANLAETTLAQF
                     ADVLSAKVVGAANLDRLLGGQPLDAFVLFSSISGVWGAGGQGAYSAANAYLDALAERRR
                     ACGRPATCIAWGPWA"
     CDS_motif       58451..58549
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnD_0037"
                     /evalue="4.20E-15"
                     /label="PKSI-KR_m1"
                     /locus_tag="spnD"
                     /protein_end="4528"
                     /protein_start="4495"
                     /score="48.2"
                     /tool="antismash"
                     /translation="TVLITGGTGALGAEVARWLARRGAEHLVLISRR"
     CDS_motif       58775..58804
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnD_0038"
                     /evalue="3.90E+00"
                     /label="PKSI-KR_m3"
                     /locus_tag="spnD"
                     /protein_end="4613"
                     /protein_start="4603"
                     /score="1.9"
                     /tool="antismash"
                     /translation="AKVVGAANLD"
     CDS_motif       58826..58936
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnD_0039"
                     /evalue="1.90E-19"
                     /label="PKSI-KR_m4"
                     /locus_tag="spnD"
                     /protein_end="4657"
                     /protein_start="4620"
                     /score="62.2"
                     /tool="antismash"
                     /translation="LDAFVLFSSISGVWGAGGQGAYSAANAYLDALAERRR"
     misc_feature    59249..59494
                     /gene="spnD"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="Region: ACP domain 7"
     aSDomain        59288..59500
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spnD_ACP.1"
                     /evalue="4.40E-31"
                     /label="spnD_ACP.1"
                     /locus_tag="spnD"
                     /protein_end="4845"
                     /protein_start="4774"
                     /score="98.9"
                     /tool="antismash"
                     /translation="LEVVLAETASTLGHDSAEAVQPDRTFAELGFDSLTAVELRNRLNA
                     VTGLRLPPTLVFDHPTPLALSEQLVP"
     aSDomain        59537..59743
                     /aSDomain="PKS_Docking_Cterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spnD_PKS_Docking_Cterm.1"
                     /evalue="2.90E-15"
                     /label="spnD_PKS_Docking_Cterm.1"
                     /locus_tag="spnD"
                     /protein_end="4926"
                     /protein_start="4857"
                     /score="48.7"
                     /tool="antismash"
                     /translation="LLAELDRLDTTLAQGPSIPLEDQAKVAERLHALLAKWDGARDGTA
                     RATSPQSLTAATDDEIFDLIDRKF"
     gene            59803..76569
                     /gene="spnE"
     CDS             59803..76569
                     /NRPS_PKS="Domain: PKS_Docking_Nterm (3-30). E-value:
                     1.8e-10. Score: 32.1. Matches aSDomain:
                     nrpspksdomains_spnE_PKS_Docking_Nterm.1"
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (35-460). E-value:
                     1.4e-182. Score: 599.2. Matches aSDomain:
                     nrpspksdomains_spnE_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (563-859). E-value: 1.3e-105.
                     Score: 344.8. Matches aSDomain:
                     nrpspksdomains_spnE_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (927-1093). E-value: 2.2e-64.
                     Score: 208.7. Matches aSDomain:
                     nrpspksdomains_spnE_PKS_DH.1"
                     /NRPS_PKS="Domain: PKS_KR (1403-1582). E-value: 5.3e-59.
                     Score: 191.1. Matches aSDomain:
                     nrpspksdomains_spnE_PKS_KR.1"
                     /NRPS_PKS="Domain: ACP (1689-1760). E-value: 4.4e-28.
                     Score: 89.3. Matches aSDomain: nrpspksdomains_spnE_ACP.1"
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (1783-2209). E-value:
                     2.1e-184. Score: 605.2. Matches aSDomain:
                     nrpspksdomains_spnE_PKS_KS.2"
                     /NRPS_PKS="Domain: PKS_AT (2320-2617). E-value: 6.5e-101.
                     Score: 329.4. Matches aSDomain:
                     nrpspksdomains_spnE_PKS_AT.2"
                     /NRPS_PKS="Domain: PKS_DH (2684-2874). E-value: 1.1e-57.
                     Score: 186.9. Matches aSDomain:
                     nrpspksdomains_spnE_PKS_DH.2"
                     /NRPS_PKS="Domain: PKS_KR (3193-3371). E-value: 3.8e-62.
                     Score: 201.3. Matches aSDomain:
                     nrpspksdomains_spnE_PKS_KR.2"
                     /NRPS_PKS="Domain: ACP (3463-3535). E-value: 1.1e-30.
                     Score: 97.6. Matches aSDomain: nrpspksdomains_spnE_ACP.2"
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (3558-3984). E-value:
                     2.3e-187. Score: 614.9. Matches aSDomain:
                     nrpspksdomains_spnE_PKS_KS.3"
                     /NRPS_PKS="Domain: PKS_AT (4093-4390). E-value: 1.9e-103.
                     Score: 337.8. Matches aSDomain:
                     nrpspksdomains_spnE_PKS_AT.3"
                     /NRPS_PKS="Domain: PKS_DH (4457-4619). E-value: 2.6e-64.
                     Score: 208.4. Matches aSDomain:
                     nrpspksdomains_spnE_PKS_DH.3"
                     /NRPS_PKS="Domain: PKS_KR (4932-5111). E-value: 9.9e-61.
                     Score: 196.7. Matches aSDomain:
                     nrpspksdomains_spnE_PKS_KR.3"
                     /NRPS_PKS="Domain: ACP (5218-5290). E-value: 1.1e-28.
                     Score: 91.2. Matches aSDomain: nrpspksdomains_spnE_ACP.3"
                     /NRPS_PKS="Domain: Thioesterase (5363-5577). E-value:
                     7.6e-27. Score: 87.0. Matches aSDomain:
                     nrpspksdomains_spnE_Thioesterase.1"
                     /codon_start=1
                     /gene="spnE"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     mod_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 292.5; E-value:
                     9.1e-89)"
                     /gene_kind="biosynthetic"
                     /note="involved in spinosyn aglycone biosynthesis"
                     /product="polyketide synthase extender modules 8-10"
                     /protein_id="AAG23262.1"
                     /sec_met_domain="PKS_AT (E-value: 5.5e-106, bitscore:
                     344.8, seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.2e-14, bitscore:
                     45.2, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="mod_KS (E-value: 2.7e-235, bitscore:
                     771.5, seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 2.8e-66, bitscore:
                     213.4, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANEEKLREYLKRVVVELEEAHERLHELERQEHDPIAIVSMGCRY
                     PGGVSTPEELWRLVVDGGDAIANFPEDRGWNLDELFDPDPGRAGTSYVREGGFLRGVAD
                     FDAGLFGISPREAQAMDPQQRLLLEISWEVFERAGIDPFSLRGTKTGVFAGLIYHDYAS
                     RFRKTPAEFEGYFATGNAGSVASGRVAYTFGLEGPAVTVDTACSSSLVALHLACQSLRL
                     GECDLALAGGISVMATPGAFVEFSRQRALASDGRCKPFADAADGTGWGEGAGMLLLERL
                     SDARRNGHPVLAAVVGSAINQDGTSNGLTAPSGPAQQRVIRQALANAGLSPAEVDVVEA
                     HGTGTALGDPIEAQALIATYGANRSADHPLLLGSLKSNIGHTQAAAGVAGVIKSVLAIR
                     HREMPRSLHIDQPSQHVDWSAGAVRLLTDSVDWPDLGRPRRAGVSSFGMSGTNAHLIVE
                     EVSDEPVSGSTEPTGAFPWPLSGKTETALREQAAELLSVVTEHPEPGLGDVGYSLATGR
                     AAMEHRAVVVADDRDSFVAGLTALAAGVPAANVVQGAADCKGKVAFVFPGQGSHWQGMA
                     RELSESSPVFRRKLAECAAATAPYVDWSLLGVLRGDPDAPALDRDDVIQLALFAMMVSL
                     AELWRSCGVEPAAVVGHSQGEIAAAHVAGALSLTDAVRIIAARCDAVSALTGKGGMLAI
                     ALPESAVVKRIAGLPELTVAAVNGPGSTVVSGEPSALERLQTELTAENVQTRRVGIDYA
                     SHSPQIAQVQGRLLDRLGEVGSEPAEIAFYSTVTGERTDTGRLDADYWYQNLRQPVRFQ
                     QTVARMADQGYRFFVEVSPHPLLTAGIQETLEAADAGGVVVGSLRRGEGGSRRWLTSLA
                     ECQVRGLPVNWEQVFLNTGARRVPLPTYPFQRQRYWLESAEYDAGDLGSVGLLSAEHPL
                     LGAAVTLADAGGFLLTGKLSVKTQPWLADHVVGGAILLPGTAFVEMLIRAADQVGCDLI
                     EELSLTTPLVLPATGAVQVQIAVGGPDEAGRRSVRVHSCRDDAVPQDSWTCHATGTLTS
                     SDHQDAGQGPDGIWPPNDAVAVPLDSFYARAAERGFDFGPAFQGLQAAWKRGDEIFAEV
                     GLPTAHREDAGRFGIHPALLDAALQALGAAEEDPDEGWLPFAWQGVSLKATGALSLRVH
                     LVPAGANAVSVFTTDTTGQAVLSIDSLVLRQISDKQLAAARAMEHESLFRVDWKRISPG
                     AAKPVSWAVIGNDELARACGSALGTELHPDLTGLADPPPDVVVVPCGASRQDLDVASEA
                     RAATQRMLDLIQDWLAAARFAGSRLVVVTCGAASTGPAEGVSDLVHAASWGLLRSAQSE
                     NPDRFVLVDVDGTAESWRALAAAVRSGEPQLALRAGEVRVPRLARCVAAEDSRIPVPGA
                     DGTVLISGGTGLLGGLVARHLVAERGVRRLVLAGRRGWSAPGVTDLVDELVGLGAAVEV
                     ASCDVGDRAQLDRLLTTISAEFPLRGVVHAAGALADGVVESLTPEHVAKVFGPKAAGAW
                     HLHELTLDLDLSFFVLFSSFSGVAGAAGQGNYAAANAFLDGLAQHRRTAGLPAVSLAWG
                     LWEQPSGMTGALDAAGRSRIARTNPPMSAPDGLRLFEMAFRVPGESLLVPVHVDLNALR
                     ADAADGGVPALLRDLVPAPVRRSAVNESADVNGLVGRLRRLPDLDQETQLLGLVREHVS
                     AVLGHSGAVEVGADRAFRDLGFDSLSGVEFRNRLGGVLGVRLPATAVFDYPTPRALVRF
                     LLDKLIGGVEAPTPAPAAVAAVTADDPVVIVGMGCRYPGGVSSPEELWRLVAGGLDAVA
                     EFPDDRGWDQAGLFDPDPDRLGTSYVCEGGFLRDAAEFDAGFFGISPREALAMDPQQRL
                     LLEVAWETVERAGIDPLSLRGSRTGVFAGLMHHDYGARFITRAPEGFEGYLGNGSAGGV
                     FSGRVAYSFGFEGPAVTVDTACSSSLVALHLAGQALRSGECDLALAGGVTVMATPGMFV
                     EFSRQRGLAADGRCKSFAAAADGTGWGEGAGLVLLERLSDARRNGHAVLAVVRGSAVNQ
                     DGASNGLTAPNGPSQQRVITQALASAGLSVSDVDAVEAHGTGTRLGDPIEAQALIATYG
                     QGRDSDRPLWLGSVKSNIGHTQAAAGVAGVIKMVMAMRHGQLPATLHVDEPTSEVDWSA
                     GDVQLLTENTPWPGNSHPRRVGVSSFGISGTNAHVILEQASKTPDETADKSGPDSESTV
                     DLPAVPLIVSGRTPAALSAQASALLSYLGERGDISTLDAAFSLASSRAALEERAVVLGA
                     DRETLLSGLEALASGREASGVVSGSPVSGGVGFVFAGQGGQWLGMGRGLYSVFPVFADA
                     FDEACAGLDAHLGQDVGVRDVVFGSDGSLLDRTLWAQSGLFALQVGLLSLLGSWGVRPG
                     VVLGHSVGEFAAAVAAGVLSLPDAARMVAGRARLMQALPSGGAMLAVAAGEEQLRPLLA
                     DRVDGAGIAAVNAPESVVLSGDREVLDDIAGALDGQGIRWRRLRVSHAFHSYRMDPMLQ
                     EFAEIARSVDYRRGDLPVVSTLTGELDTAGVMATPEYWVRQVREPVRFADGVRVLAQQG
                     VATIFELGPDATLSALIPDCHSWADQAMPIPMLRKDRTETETVVAAVARAHTRGVPVEW
                     SAYFAGTGARRVELPTYAFQRQRYWLETSDYGDVTGIGLAAAEHPLLGAVVALADGDGM
                     VLTGRLSVGTHPWLAQHRVLGEVVVPGTAILEMALHAGARLGCDRVEELTLETPLVVPE
                     RAAGAGSRGPAGGTTVSIETAEERVRTNDAIEIQLLVNAPDEGGRRRVSLYSRPAGGSR
                     GGGWTRHATGELVVGTTGGRAVPDWSAEGAESIALDEFYVALAGNGFEYGPLFQGLQAA
                     WRRGDEVLAEIAPPAEADAMASGYLLDPALLDAALQASALGDRPEQGGAWLPFSFTGVE
                     LSAPAGTISRVRLETRRPDAISVAVMDESGRLLASIDSLRLRSVSSGQLANRDAVRDAL
                     FEVTWEPVATQSTEPGRWALLGDTACGKDDLIKLATDSADRCADLAALAEKLDSSALVP
                     DVVVYCAGEQADPGTGAAALAETQQTLALLQAWLAEPRLAEARLVVVTCAAVTTAPSDG
                     ASELAHAPLWGLLRAAQVENPGQFVLADVDGTAESWRALPSALGSMEPQLALRKGAVRA
                     PRLASVAGQIDVPAVVADPDRTVLISGGTGLLGGAVARHLVTERGVRRLVLTGRRGWDA
                     PGITELVGELNGLGAVVDVVACDVADRADLESLLAAVPAEFPLCGVVHAAGALADGVIE
                     SLSPDDVGAVFGPKAAGAWNLHELTRDTDLSFFALFSSLSGVAGAPGQGNYAAANAFLD
                     ALAHYRRSQGLPAVSLAWGLWEQPSGMTETLSEVDRSRIARANPPLSTKEGLRLFDAGL
                     ALDRAAVVPAKLDRTFLAEQARSGSLPALLTALVPPIRRNRRASGTELADEGTLLGVVR
                     EHAAAVLGYSSAADVGVERAFRDLGFDSLSGVELRNRLAGVLGVRLPATAVFDYPTPRA
                     LARFLHQELADEIATTPAPVTTTRAPVAEDDLVAIVGMGCRFPGQVSSPEELWRLVAGG
                     VDAVADFPADRGWDLAGLFDPDPERAGKTYVREGAFLTDADRFDAGFFGISPREALAMD
                     PQQRLLLELSWEAIERAGIDPGSLRGSRTGVFAGLMYHDYGARFASRAPEGFEGYLGNG
                     SAGSVASGRIAYSFGFEGPAVTVDTACSSSLVALHLAGQSLRSGECDLALAGGVTVMST
                     PGTFVEFSRQRGLAPDGRCKSFAESADGTGWGEGAGLVLLERLSDARRNGHRVLAVVRG
                     SAVNQDGASNGLTAPNGPSQQRVIQQALASAGLSVSDVDAVEAHGTGTRLGDPIEAQAL
                     IATYGRDRDPGRPLWLGSVKSNIGHTQAAAGVAGVIKMVMAMRHGQLPRTLHVDAPSSQ
                     VDWSAGRVQLLTENTPWPDSGRPCRVGVSSFGISGTNAHVILEQSTGQMDQAAEPDSSP
                     VLDVPVVPWVVSGKTPEALSAQAATLATYLDQNVDVSPLDVGISLAVTRSALDERAVVL
                     GSDRDTLLSGLNALAAGHEAAGVVTGPVGIGGRTGFVFAGQGGQWLGMGRRLYSEFPAF
                     AGAFDEACAELDANLGREVGVRDVVFGSDESLLDRTLWAQSGLFALQVGLWELLGTWGV
                     RPSVVLGHSVGELAAAFAAGVLSMAEAARLVAGRARLMQALPSGGAMLAVSATEARVGP
                     LLDGVRDRVGVAAVNAPGSVVLSGDRDVLDGIAGRLDGQGIRSRWLRVSHAFHSHRMDP
                     MLAEFAELARSVDYRSPRLPIVSTLTGNLDDVGVMATPEYWVRQVREPVRFADGVQALV
                     DQGVDTIVELGPDGALSSLVQECVAESGRATGIPLVRRDRDEVRTVLDALAQTHTRGGA
                     VDWGSFFAGTRATQVDLPTYAFQRQRYWLEPSDSGDVTGVGLTGAEHPLLGAVVPVAGG
                     DEVLLTGRLSVGTHPWLAEHRVLGEVVVPGTALLEMAWRAGSQVGCERVEELTLEAPLV
                     LPERGAAAVQLAVGAPDEAGRRSLQLYSRGADEDGDWRRIASGLLAQANAVPPADSTAW
                     PPDGAGQVDLAEFYERLAERGLTYGPVFQGLRAAWRHGDDIFAELAGSPDASGFGIHPA
                     LLDAALHAMALGASPDSEARLPFSWRGAQLYRAEGAALRVRLSPLGSGAVSLTLVDATG
                     RRVAAVESLSTRPVSTDQIGAGRGDQERLLHVEWVRSAESAGMSLTSCAVVGLGEPEWH
                     AALKTTGVQVESHADLASLATEVAKRGSAPGAVIVPCPRPRAMQELPTAARRATQQAMA
                     MLQQWLADDRFVSTRLILLTHRAVSAVAGEDVLDLVHAPLWGLVRSAQAEHPDRFALID
                     MDDERASQTALAEALTAGEAQLAVRSGVVLAPRLGQVKVSGGEAFRWDEGTVLVTGGTG
                     GLGALLARHLVSAHGVRHLLLASRRGLAAPGADELVAELEQAGADVAVVACDSADRDSL
                     ARLVASVPAENPLRVVVHAAGVLDDGVLMSMSPERLDAVLRPKVDAAWYLHELTRELGL
                     SAFVLFSSVAGLFGGAGQSNYAAGNAFLDALAHCRQAQGLPALSLASGLWASIDGMAGD
                     LAAADVERLSRAGIGPLSAPGGLALFDAAVGSDEPLLAPVRLDVEALRVQARSVQTRIP
                     EMLHGMAMGPSRRTPFTSRVEPLHERLAGLSEGERRQQVLQRVRADIAVVLGHGRSSDV
                     DIEKPLAELGFDSLTAIELRNRLATATGLRLPATLAFDHGTAAALAQHVCAQLGTATAP
                     APRRTDDNDATEPVRSLFQQAYAAGRILDGMDLVKVAAQLRPVFGSPGELESLPKPVQL
                     SRGPEELALVCMPALIGMPPAQQYARIAAGFRDVRDVSVIPMPGFIAGEPLPSAIEVAV
                     RTQAEAVLQEFAGGSFVLVGHSSGGWLAHEVAGELERRGVVPAGVVLLDTYIPGEITPR
                     FSVAMAHRTYEKLATFTDMQDVGITAMGGYFRMFTEWTPTPIGAPTLFVRTEDCVADPE
                     GRPWTDDSWRPGWTLADATVQVPGDHFSMMDEHAGSTAQAVASWLDKLNQRTARQR"
     aSDomain        59812..59892
                     /aSDomain="PKS_Docking_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spnE_PKS_Docking_Nterm.1"
                     /evalue="1.80E-10"
                     /label="spnE_PKS_Docking_Nterm.1"
                     /locus_tag="spnE"
                     /protein_end="30"
                     /protein_start="3"
                     /score="32.1"
                     /tool="antismash"
                     /translation="EEKLREYLKRVVVELEEAHERLHELER"
     misc_feature    59902..61173
                     /gene="spnE"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="Region: ketosynthase domain 8"
     misc_feature    59902..65079
                     /gene="spnE"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="Region: extender module 8"
     aSDomain        59908..61182
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spnE_PKS_KS.1"
                     /domain_subtypes="Modular-KS"
                     /evalue="1.40E-182"
                     /label="spnE_PKS_KS.1"
                     /locus_tag="spnE"
                     /protein_end="460"
                     /protein_start="35"
                     /score="599.2"
                     /tool="antismash"
                     /translation="IAIVSMGCRYPGGVSTPEELWRLVVDGGDAIANFPEDRGWNLDEL
                     FDPDPGRAGTSYVREGGFLRGVADFDAGLFGISPREAQAMDPQQRLLLEISWEVFERAG
                     IDPFSLRGTKTGVFAGLIYHDYASRFRKTPAEFEGYFATGNAGSVASGRVAYTFGLEGP
                     AVTVDTACSSSLVALHLACQSLRLGECDLALAGGISVMATPGAFVEFSRQRALASDGRC
                     KPFADAADGTGWGEGAGMLLLERLSDARRNGHPVLAAVVGSAINQDGTSNGLTAPSGPA
                     QQRVIRQALANAGLSPAEVDVVEAHGTGTALGDPIEAQALIATYGANRSADHPLLLGSL
                     KSNIGHTQAAAGVAGVIKSVLAIRHREMPRSLHIDQPSQHVDWSAGAVRLLTDSVDWPD
                     LGRPRRAGVSSFGMSGTNAHLIVEEV"
     aSModule        59908..65082
                     /complete
                     /domains="nrpspksdomains_spnE_PKS_KS.1"
                     /domains="nrpspksdomains_spnE_PKS_AT.1"
                     /domains="nrpspksdomains_spnE_PKS_DH.1"
                     /domains="nrpspksdomains_spnE_PKS_KR.1"
                     /domains="nrpspksdomains_spnE_ACP.1"
                     /locus_tags="spnE"
                     /monomer_pairings="mmal -> Me-ccmal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       60163..60189
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnE_0001"
                     /evalue="1.10E-01"
                     /label="PKSI-KS_m2"
                     /locus_tag="spnE"
                     /protein_end="129"
                     /protein_start="120"
                     /score="5.9"
                     /tool="antismash"
                     /translation="DPQQRLLLE"
     misc_feature    60385..60387
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     CDS_motif       60391..60438
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnE_0002"
                     /evalue="3.20E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="spnE"
                     /protein_end="212"
                     /protein_start="196"
                     /score="19.1"
                     /tool="antismash"
                     /translation="GPAVTVDTACSSSLVA"
     CDS_motif       60814..60858
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnE_0003"
                     /evalue="1.60E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="spnE"
                     /protein_end="352"
                     /protein_start="337"
                     /score="11.0"
                     /tool="antismash"
                     /translation="VEAHGTGTALGDPIE"
     CDS_motif       60919..60963
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnE_0004"
                     /evalue="8.90E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="spnE"
                     /protein_end="387"
                     /protein_start="372"
                     /score="9.1"
                     /tool="antismash"
                     /translation="GSLKSNIGHTQAAAG"
     CDS_motif       61489..61539
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnE_0005"
                     /evalue="1.80E-07"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="spnE"
                     /protein_end="579"
                     /protein_start="562"
                     /score="23.2"
                     /tool="antismash"
                     /translation="FVFPGQGSHWQGMAREL"
     misc_feature    61489..62445
                     /gene="spnE"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="Region: acyltransferase domain 8"
     aSDomain        61492..62379
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spnE_PKS_AT.1"
                     /evalue="1.30E-105"
                     /label="spnE_PKS_AT.1"
                     /locus_tag="spnE"
                     /protein_end="859"
                     /protein_start="563"
                     /score="344.8"
                     /specificity="substrate consensus: mmal"
                     /specificity="PKS signature: Methylmalonyl-CoA"
                     /specificity="Minowa: mmal"
                     /tool="antismash"
                     /translation="VFPGQGSHWQGMARELSESSPVFRRKLAECAAATAPYVDWSLLGV
                     LRGDPDAPALDRDDVIQLALFAMMVSLAELWRSCGVEPAAVVGHSQGEIAAAHVAGALS
                     LTDAVRIIAARCDAVSALTGKGGMLAIALPESAVVKRIAGLPELTVAAVNGPGSTVVSG
                     EPSALERLQTELTAENVQTRRVGIDYASHSPQIAQVQGRLLDRLGEVGSEPAEIAFYST
                     VTGERTDTGRLDADYWYQNLRQPVRFQQTVARMADQGYRFFVEVSPHPLLTAGIQETLE
                     AADAGGVVVGSLRRG"
     CDS_motif       61657..61725
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnE_0006"
                     /evalue="9.10E-07"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="spnE"
                     /protein_end="641"
                     /protein_start="618"
                     /score="21.6"
                     /tool="antismash"
                     /translation="DRDDVIQLALFAMMVSLAELWRS"
     CDS_motif       61729..61836
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnE_0007"
                     /evalue="2.90E-18"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="spnE"
                     /protein_end="678"
                     /protein_start="642"
                     /score="57.7"
                     /tool="antismash"
                     /translation="GVEPAAVVGHSQGEIAAAHVAGALSLTDAVRIIAAR"
     CDS_motif       61942..61980
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnE_0008"
                     /evalue="4.00E-03"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="spnE"
                     /protein_end="726"
                     /protein_start="713"
                     /score="10.6"
                     /tool="antismash"
                     /translation="AAVNGPGSTVVSG"
     CDS_motif       62188..62235
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnE_0009"
                     /evalue="1.40E-05"
                     /label="PKSI-AT-mM_m8"
                     /locus_tag="spnE"
                     /protein_end="811"
                     /protein_start="795"
                     /score="17.0"
                     /tool="antismash"
                     /translation="LDADYWYQNLRQPVRF"
     misc_feature    62548..63111
                     /gene="spnE"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="Region: dehydratase domain 8"
     aSDomain        62584..63081
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spnE_PKS_DH.1"
                     /evalue="2.20E-64"
                     /label="spnE_PKS_DH.1"
                     /locus_tag="spnE"
                     /protein_end="1093"
                     /protein_start="927"
                     /score="208.7"
                     /tool="antismash"
                     /translation="HPLLGAAVTLADAGGFLLTGKLSVKTQPWLADHVVGGAILLPGTA
                     FVEMLIRAADQVGCDLIEELSLTTPLVLPATGAVQVQIAVGGPDEAGRRSVRVHSCRDD
                     AVPQDSWTCHATGTLTSSDHQDAGQGPDGIWPPNDAVAVPLDSFYARAAERGFDFGPAF
                     QGL"
     CDS_motif       62668..62745
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnE_0010"
                     /evalue="8.00E-11"
                     /label="PKSI-DH_m2"
                     /locus_tag="spnE"
                     /protein_end="981"
                     /protein_start="955"
                     /score="34.4"
                     /tool="antismash"
                     /translation="WLADHVVGGAILLPGTAFVEMLIRAA"
     CDS_motif       63049..63081
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnE_0011"
                     /evalue="4.60E-01"
                     /label="PKSI-DH_m3"
                     /locus_tag="spnE"
                     /protein_end="1093"
                     /protein_start="1082"
                     /score="4.2"
                     /tool="antismash"
                     /translation="GFDFGPAFQGL"
     misc_feature    64006..64557
                     /gene="spnE"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="Region: ketoreductase domain 8"
     aSDomain        64012..64548
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spnE_PKS_KR.1"
                     /evalue="5.30E-59"
                     /label="spnE_PKS_KR.1"
                     /locus_tag="spnE"
                     /protein_end="1582"
                     /protein_start="1403"
                     /score="191.1"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="GTVLISGGTGLLGGLVARHLVAERGVRRLVLAGRRGWSAPGVTDL
                     VDELVGLGAAVEVASCDVGDRAQLDRLLTTISAEFPLRGVVHAAGALADGVVESLTPEH
                     VAKVFGPKAAGAWHLHELTLDLDLSFFVLFSSFSGVAGAAGQGNYAAANAFLDGLAQHR
                     RTAGLPAVSLAWGLWE"
     CDS_motif       64015..64116
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnE_0012"
                     /evalue="5.30E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="spnE"
                     /protein_end="1438"
                     /protein_start="1404"
                     /score="19.1"
                     /tool="antismash"
                     /translation="TVLISGGTGLLGGLVARHLVAERGVRRLVLAGRR"
     CDS_motif       64342..64371
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnE_0013"
                     /evalue="3.50E-02"
                     /label="PKSI-KR_m3"
                     /locus_tag="spnE"
                     /protein_end="1523"
                     /protein_start="1513"
                     /score="7.9"
                     /tool="antismash"
                     /translation="PKAAGAWHLH"
     CDS_motif       64393..64503
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnE_0014"
                     /evalue="2.10E-19"
                     /label="PKSI-KR_m4"
                     /locus_tag="spnE"
                     /protein_end="1567"
                     /protein_start="1530"
                     /score="62.1"
                     /tool="antismash"
                     /translation="LSFFVLFSSFSGVAGAAGQGNYAAANAFLDGLAQHRR"
     misc_feature    64843..65079
                     /gene="spnE"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="Region: ACP domain 8"
     aSDomain        64870..65082
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spnE_ACP.1"
                     /evalue="4.40E-28"
                     /label="spnE_ACP.1"
                     /locus_tag="spnE"
                     /protein_end="1760"
                     /protein_start="1689"
                     /score="89.3"
                     /tool="antismash"
                     /translation="GLVREHVSAVLGHSGAVEVGADRAFRDLGFDSLSGVEFRNRLGGV
                     LGVRLPATAVFDYPTPRALVRFLLDK"
     misc_feature    65146..66420
                     /gene="spnE"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="Region: ketosynthase domain 9"
     misc_feature    65146..70401
                     /gene="spnE"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="Region: extender module 9"
     aSDomain        65152..66429
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spnE_PKS_KS.2"
                     /domain_subtypes="Modular-KS"
                     /evalue="2.10E-184"
                     /label="spnE_PKS_KS.2"
                     /locus_tag="spnE"
                     /protein_end="2209"
                     /protein_start="1783"
                     /score="605.2"
                     /tool="antismash"
                     /translation="VVIVGMGCRYPGGVSSPEELWRLVAGGLDAVAEFPDDRGWDQAGL
                     FDPDPDRLGTSYVCEGGFLRDAAEFDAGFFGISPREALAMDPQQRLLLEVAWETVERAG
                     IDPLSLRGSRTGVFAGLMHHDYGARFITRAPEGFEGYLGNGSAGGVFSGRVAYSFGFEG
                     PAVTVDTACSSSLVALHLAGQALRSGECDLALAGGVTVMATPGMFVEFSRQRGLAADGR
                     CKSFAAAADGTGWGEGAGLVLLERLSDARRNGHAVLAVVRGSAVNQDGASNGLTAPNGP
                     SQQRVITQALASAGLSVSDVDAVEAHGTGTRLGDPIEAQALIATYGQGRDSDRPLWLGS
                     VKSNIGHTQAAAGVAGVIKMVMAMRHGQLPATLHVDEPTSEVDWSAGDVQLLTENTPWP
                     GNSHPRRVGVSSFGISGTNAHVILEQA"
     aSModule        65152..70407
                     /complete
                     /domains="nrpspksdomains_spnE_PKS_KS.2"
                     /domains="nrpspksdomains_spnE_PKS_AT.2"
                     /domains="nrpspksdomains_spnE_PKS_DH.2"
                     /domains="nrpspksdomains_spnE_PKS_KR.2"
                     /domains="nrpspksdomains_spnE_ACP.2"
                     /locus_tags="spnE"
                     /monomer_pairings="mal -> ccmal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       65407..65433
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnE_0015"
                     /evalue="1.10E-01"
                     /label="PKSI-KS_m2"
                     /locus_tag="spnE"
                     /protein_end="1877"
                     /protein_start="1868"
                     /score="5.9"
                     /tool="antismash"
                     /translation="DPQQRLLLE"
     CDS_motif       65638..65685
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnE_0016"
                     /evalue="3.20E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="spnE"
                     /protein_end="1961"
                     /protein_start="1945"
                     /score="19.1"
                     /tool="antismash"
                     /translation="GPAVTVDTACSSSLVA"
     CDS_motif       66061..66105
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnE_0017"
                     /evalue="1.70E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="spnE"
                     /protein_end="2101"
                     /protein_start="2086"
                     /score="10.9"
                     /tool="antismash"
                     /translation="VEAHGTGTRLGDPIE"
     CDS_motif       66166..66210
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnE_0018"
                     /evalue="2.80E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="spnE"
                     /protein_end="2136"
                     /protein_start="2121"
                     /score="10.4"
                     /tool="antismash"
                     /translation="GSVKSNIGHTQAAAG"
     CDS_motif       66760..66813
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnE_0019"
                     /evalue="2.90E-05"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="spnE"
                     /protein_end="2337"
                     /protein_start="2319"
                     /score="16.5"
                     /tool="antismash"
                     /translation="FVFAGQGGQWLGMGRGLY"
     misc_feature    66760..67743
                     /gene="spnE"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="Region: acyltransferase domain 9"
     aSDomain        66763..67653
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spnE_PKS_AT.2"
                     /evalue="6.50E-101"
                     /label="spnE_PKS_AT.2"
                     /locus_tag="spnE"
                     /protein_end="2617"
                     /protein_start="2320"
                     /score="329.4"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="VFAGQGGQWLGMGRGLYSVFPVFADAFDEACAGLDAHLGQDVGVR
                     DVVFGSDGSLLDRTLWAQSGLFALQVGLLSLLGSWGVRPGVVLGHSVGEFAAAVAAGVL
                     SLPDAARMVAGRARLMQALPSGGAMLAVAAGEEQLRPLLADRVDGAGIAAVNAPESVVL
                     SGDREVLDDIAGALDGQGIRWRRLRVSHAFHSYRMDPMLQEFAEIARSVDYRRGDLPVV
                     STLTGELDTAGVMATPEYWVRQVREPVRFADGVRVLAQQGVATIFELGPDATLSALIPD
                     CHSWADQAMPIPMLRK"
     CDS_motif       67003..67125
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnE_0020"
                     /evalue="2.40E-20"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="spnE"
                     /protein_end="2441"
                     /protein_start="2400"
                     /score="64.7"
                     /tool="antismash"
                     /translation="GVRPGVVLGHSVGEFAAAVAAGVLSLPDAARMVAGRARLMQ"
     CDS_motif       67219..67257
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnE_0021"
                     /evalue="6.40E-03"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="spnE"
                     /protein_end="2485"
                     /protein_start="2472"
                     /score="9.9"
                     /tool="antismash"
                     /translation="AAVNAPESVVLSG"
     CDS_motif       67321..67347
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnE_0022"
                     /evalue="1.20E-01"
                     /label="PKSI-AT-M_m6"
                     /locus_tag="spnE"
                     /protein_end="2515"
                     /protein_start="2506"
                     /score="5.9"
                     /tool="antismash"
                     /translation="LRVSHAFHS"
     CDS_motif       67480..67515
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnE_0023"
                     /evalue="2.00E-04"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="spnE"
                     /protein_end="2571"
                     /protein_start="2559"
                     /score="14.8"
                     /tool="antismash"
                     /translation="YWVRQVREPVRF"
     misc_feature    67819..68301
                     /gene="spnE"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="Region: dehydratase domain 9"
     aSDomain        67855..68424
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spnE_PKS_DH.2"
                     /evalue="1.10E-57"
                     /label="spnE_PKS_DH.2"
                     /locus_tag="spnE"
                     /protein_end="2874"
                     /protein_start="2684"
                     /score="186.9"
                     /tool="antismash"
                     /translation="HPLLGAVVALADGDGMVLTGRLSVGTHPWLAQHRVLGEVVVPGTA
                     ILEMALHAGARLGCDRVEELTLETPLVVPERAAGAGSRGPAGGTTVSIETAEERVRTND
                     AIEIQLLVNAPDEGGRRRVSLYSRPAGGSRGGGWTRHATGELVVGTTGGRAVPDWSAEG
                     AESIALDEFYVALAGNGFEYGPLFQGL"
     CDS_motif       67939..68013
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnE_0024"
                     /evalue="8.40E-10"
                     /label="PKSI-DH_m2"
                     /locus_tag="spnE"
                     /protein_end="2737"
                     /protein_start="2712"
                     /score="31.1"
                     /tool="antismash"
                     /translation="WLAQHRVLGEVVVPGTAILEMALHA"
     CDS_motif       68290..68361
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnE_0025"
                     /evalue="1.40E+01"
                     /label="PKSI-KR_m1"
                     /locus_tag="spnE"
                     /protein_end="2853"
                     /protein_start="2829"
                     /score="-1.5"
                     /tool="antismash"
                     /translation="LVVGTTGGRAVPDWSAEGAESIAL"
     CDS_motif       68392..68424
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnE_0026"
                     /evalue="2.40E-01"
                     /label="PKSI-DH_m3"
                     /locus_tag="spnE"
                     /protein_end="2874"
                     /protein_start="2863"
                     /score="5.0"
                     /tool="antismash"
                     /translation="GFEYGPLFQGL"
     misc_feature    69370..69924
                     /gene="spnE"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="Region: ketoreductase domain 9"
     CDS_motif       69382..69483
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnE_0027"
                     /evalue="1.10E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="spnE"
                     /protein_end="3227"
                     /protein_start="3193"
                     /score="21.2"
                     /tool="antismash"
                     /translation="TVLISGGTGLLGGAVARHLVTERGVRRLVLTGRR"
     aSDomain        69382..69915
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spnE_PKS_KR.2"
                     /evalue="3.80E-62"
                     /label="spnE_PKS_KR.2"
                     /locus_tag="spnE"
                     /protein_end="3371"
                     /protein_start="3193"
                     /score="201.3"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="TVLISGGTGLLGGAVARHLVTERGVRRLVLTGRRGWDAPGITELV
                     GELNGLGAVVDVVACDVADRADLESLLAAVPAEFPLCGVVHAAGALADGVIESLSPDDV
                     GAVFGPKAAGAWNLHELTRDTDLSFFALFSSLSGVAGAPGQGNYAAANAFLDALAHYRR
                     SQGLPAVSLAWGLWE"
     CDS_motif       69709..69738
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnE_0028"
                     /evalue="1.80E-02"
                     /label="PKSI-KR_m3"
                     /locus_tag="spnE"
                     /protein_end="3312"
                     /protein_start="3302"
                     /score="8.8"
                     /tool="antismash"
                     /translation="PKAAGAWNLH"
     CDS_motif       69760..69870
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnE_0029"
                     /evalue="7.20E-20"
                     /label="PKSI-KR_m4"
                     /locus_tag="spnE"
                     /protein_end="3356"
                     /protein_start="3319"
                     /score="63.6"
                     /tool="antismash"
                     /translation="LSFFALFSSLSGVAGAPGQGNYAAANAFLDALAHYRR"
     misc_feature    70165..70401
                     /gene="spnE"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="Region: ACP domain 9"
     aSDomain        70192..70407
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spnE_ACP.2"
                     /evalue="1.10E-30"
                     /label="spnE_ACP.2"
                     /locus_tag="spnE"
                     /protein_end="3535"
                     /protein_start="3463"
                     /score="97.6"
                     /tool="antismash"
                     /translation="GVVREHAAAVLGYSSAADVGVERAFRDLGFDSLSGVELRNRLAGV
                     LGVRLPATAVFDYPTPRALARFLHQEL"
     misc_feature    70471..71745
                     /gene="spnE"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="Region: ketosynthase domain 10"
     misc_feature    70471..76566
                     /gene="spnE"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="Region: extender module 10"
     aSDomain        70477..71754
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spnE_PKS_KS.3"
                     /domain_subtypes="Modular-KS"
                     /evalue="2.30E-187"
                     /label="spnE_PKS_KS.3"
                     /locus_tag="spnE"
                     /protein_end="3984"
                     /protein_start="3558"
                     /score="614.9"
                     /tool="antismash"
                     /translation="VAIVGMGCRFPGQVSSPEELWRLVAGGVDAVADFPADRGWDLAGL
                     FDPDPERAGKTYVREGAFLTDADRFDAGFFGISPREALAMDPQQRLLLELSWEAIERAG
                     IDPGSLRGSRTGVFAGLMYHDYGARFASRAPEGFEGYLGNGSAGSVASGRIAYSFGFEG
                     PAVTVDTACSSSLVALHLAGQSLRSGECDLALAGGVTVMSTPGTFVEFSRQRGLAPDGR
                     CKSFAESADGTGWGEGAGLVLLERLSDARRNGHRVLAVVRGSAVNQDGASNGLTAPNGP
                     SQQRVIQQALASAGLSVSDVDAVEAHGTGTRLGDPIEAQALIATYGRDRDPGRPLWLGS
                     VKSNIGHTQAAAGVAGVIKMVMAMRHGQLPRTLHVDAPSSQVDWSAGRVQLLTENTPWP
                     DSGRPCRVGVSSFGISGTNAHVILEQS"
     aSModule        70477..76533
                     /complete
                     /domains="nrpspksdomains_spnE_PKS_KS.3"
                     /domains="nrpspksdomains_spnE_PKS_AT.3"
                     /domains="nrpspksdomains_spnE_PKS_DH.3"
                     /domains="nrpspksdomains_spnE_PKS_KR.3"
                     /domains="nrpspksdomains_spnE_ACP.3"
                     /domains="nrpspksdomains_spnE_Thioesterase.1"
                     /final_module
                     /locus_tags="spnE"
                     /monomer_pairings="mal -> ccmal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       70732..70758
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnE_0030"
                     /evalue="1.10E-01"
                     /label="PKSI-KS_m2"
                     /locus_tag="spnE"
                     /protein_end="3652"
                     /protein_start="3643"
                     /score="5.9"
                     /tool="antismash"
                     /translation="DPQQRLLLE"
     CDS_motif       70963..71010
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnE_0031"
                     /evalue="3.20E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="spnE"
                     /protein_end="3736"
                     /protein_start="3720"
                     /score="19.1"
                     /tool="antismash"
                     /translation="GPAVTVDTACSSSLVA"
     CDS_motif       71386..71430
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnE_0032"
                     /evalue="1.70E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="spnE"
                     /protein_end="3876"
                     /protein_start="3861"
                     /score="10.9"
                     /tool="antismash"
                     /translation="VEAHGTGTRLGDPIE"
     CDS_motif       71491..71535
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnE_0033"
                     /evalue="2.80E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="spnE"
                     /protein_end="3911"
                     /protein_start="3896"
                     /score="10.4"
                     /tool="antismash"
                     /translation="GSVKSNIGHTQAAAG"
     CDS_motif       72079..72132
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnE_0034"
                     /evalue="1.40E-05"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="spnE"
                     /protein_end="4110"
                     /protein_start="4092"
                     /score="17.5"
                     /tool="antismash"
                     /translation="FVFAGQGGQWLGMGRRLY"
     misc_feature    72079..73071
                     /gene="spnE"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="Region: acyltransferase domain 10"
     aSDomain        72082..72972
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spnE_PKS_AT.3"
                     /evalue="1.90E-103"
                     /label="spnE_PKS_AT.3"
                     /locus_tag="spnE"
                     /protein_end="4390"
                     /protein_start="4093"
                     /score="337.8"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="VFAGQGGQWLGMGRRLYSEFPAFAGAFDEACAELDANLGREVGVR
                     DVVFGSDESLLDRTLWAQSGLFALQVGLWELLGTWGVRPSVVLGHSVGELAAAFAAGVL
                     SMAEAARLVAGRARLMQALPSGGAMLAVSATEARVGPLLDGVRDRVGVAAVNAPGSVVL
                     SGDRDVLDGIAGRLDGQGIRSRWLRVSHAFHSHRMDPMLAEFAELARSVDYRSPRLPIV
                     STLTGNLDDVGVMATPEYWVRQVREPVRFADGVQALVDQGVDTIVELGPDGALSSLVQE
                     CVAESGRATGIPLVRR"
     CDS_motif       72322..72444
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnE_0035"
                     /evalue="2.80E-18"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="spnE"
                     /protein_end="4214"
                     /protein_start="4173"
                     /score="58.1"
                     /tool="antismash"
                     /translation="GVRPSVVLGHSVGELAAAFAAGVLSMAEAARLVAGRARLMQ"
     CDS_motif       72538..72576
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnE_0036"
                     /evalue="4.70E-02"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="spnE"
                     /protein_end="4258"
                     /protein_start="4245"
                     /score="7.3"
                     /tool="antismash"
                     /translation="AAVNAPGSVVLSG"
     CDS_motif       72640..72666
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnE_0037"
                     /evalue="1.20E-01"
                     /label="PKSI-AT-M_m6"
                     /locus_tag="spnE"
                     /protein_end="4288"
                     /protein_start="4279"
                     /score="5.9"
                     /tool="antismash"
                     /translation="LRVSHAFHS"
     CDS_motif       72799..72834
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnE_0038"
                     /evalue="2.00E-04"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="spnE"
                     /protein_end="4344"
                     /protein_start="4332"
                     /score="14.8"
                     /tool="antismash"
                     /translation="YWVRQVREPVRF"
     misc_feature    73138..73692
                     /gene="spnE"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="Region: dehydratase domain 10"
     aSDomain        73174..73659
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spnE_PKS_DH.3"
                     /evalue="2.60E-64"
                     /label="spnE_PKS_DH.3"
                     /locus_tag="spnE"
                     /protein_end="4619"
                     /protein_start="4457"
                     /score="208.4"
                     /tool="antismash"
                     /translation="HPLLGAVVPVAGGDEVLLTGRLSVGTHPWLAEHRVLGEVVVPGTA
                     LLEMAWRAGSQVGCERVEELTLEAPLVLPERGAAAVQLAVGAPDEAGRRSLQLYSRGAD
                     EDGDWRRIASGLLAQANAVPPADSTAWPPDGAGQVDLAEFYERLAERGLTYGPVFQGL"
     CDS_motif       73258..73332
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnE_0039"
                     /evalue="7.20E-10"
                     /label="PKSI-DH_m2"
                     /locus_tag="spnE"
                     /protein_end="4510"
                     /protein_start="4485"
                     /score="31.3"
                     /tool="antismash"
                     /translation="WLAEHRVLGEVVVPGTALLEMAWRA"
     CDS_motif       73627..73659
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnE_0040"
                     /evalue="1.50E-01"
                     /label="PKSI-DH_m3"
                     /locus_tag="spnE"
                     /protein_end="4619"
                     /protein_start="4608"
                     /score="5.7"
                     /tool="antismash"
                     /translation="GLTYGPVFQGL"
     misc_feature    74599..75135
                     /gene="spnE"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="Region: ketoreductase domain 10"
     aSDomain        74599..75135
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spnE_PKS_KR.3"
                     /evalue="9.90E-61"
                     /label="spnE_PKS_KR.3"
                     /locus_tag="spnE"
                     /protein_end="5111"
                     /protein_start="4932"
                     /score="196.7"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: B1"
                     /tool="antismash"
                     /translation="GTVLVTGGTGGLGALLARHLVSAHGVRHLLLASRRGLAAPGADEL
                     VAELEQAGADVAVVACDSADRDSLARLVASVPAENPLRVVVHAAGVLDDGVLMSMSPER
                     LDAVLRPKVDAAWYLHELTRELGLSAFVLFSSVAGLFGGAGQSNYAAGNAFLDALAHCR
                     QAQGLPALSLASGLWA"
     CDS_motif       74602..74703
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnE_0041"
                     /evalue="2.00E-09"
                     /label="PKSI-KR_m1"
                     /locus_tag="spnE"
                     /protein_end="4967"
                     /protein_start="4933"
                     /score="30.1"
                     /tool="antismash"
                     /translation="TVLVTGGTGGLGALLARHLVSAHGVRHLLLASRR"
     CDS_motif       74929..74958
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnE_0042"
                     /evalue="8.00E-02"
                     /label="PKSI-KR_m3"
                     /locus_tag="spnE"
                     /protein_end="5052"
                     /protein_start="5042"
                     /score="6.8"
                     /tool="antismash"
                     /translation="PKVDAAWYLH"
     CDS_motif       74986..75090
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnE_0043"
                     /evalue="2.00E-18"
                     /label="PKSI-KR_m4"
                     /locus_tag="spnE"
                     /protein_end="5096"
                     /protein_start="5061"
                     /score="58.9"
                     /tool="antismash"
                     /translation="AFVLFSSVAGLFGGAGQSNYAAGNAFLDALAHCRQ"
     misc_feature    75415..75660
                     /gene="spnE"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="Region: ACP domain 10"
     aSDomain        75457..75672
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spnE_ACP.3"
                     /evalue="1.10E-28"
                     /label="spnE_ACP.3"
                     /locus_tag="spnE"
                     /protein_end="5290"
                     /protein_start="5218"
                     /score="91.2"
                     /tool="antismash"
                     /translation="QRVRADIAVVLGHGRSSDVDIEKPLAELGFDSLTAIELRNRLATA
                     TGLRLPATLAFDHGTAAALAQHVCAQL"
     misc_feature    75805..76566
                     /gene="spnE"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="Region: thioesterase domain 10"
     aSDomain        75892..76533
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spnE_Thioesterase.1"
                     /evalue="7.60E-27"
                     /label="spnE_Thioesterase.1"
                     /locus_tag="spnE"
                     /protein_end="5577"
                     /protein_start="5363"
                     /score="87.0"
                     /tool="antismash"
                     /translation="LVCMPALIGMPPAQQYARIAAGFRDVRDVSVIPMPGFIAGEPLPS
                     AIEVAVRTQAEAVLQEFAGGSFVLVGHSSGGWLAHEVAGELERRGVVPAGVVLLDTYIP
                     GEITPRFSVAMAHRTYEKLATFTDMQDVGITAMGGYFRMFTEWTPTPIGAPTLFVRTED
                     CVADPEGRPWTDDSWRPGWTLADATVQVPGDHFSMMDEHAGSTAQAVASWL"
     CDS_motif       76084..76149
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_spnE_0044"
                     /evalue="5.90E-07"
                     /label="NRPS-te1"
                     /locus_tag="spnE"
                     /protein_end="5449"
                     /protein_start="5427"
                     /score="22.0"
                     /tool="antismash"
                     /translation="GSFVLVGHSSGGWLAHEVAGEL"
     CDS             76932..77528
                     /codon_start=1
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="ORF R1"
                     /product="unknown"
                     /protein_id="AAG23284.1"
                     /transl_table=11
                     /translation="MMLKRHRLTTAITGLLGGVLLVSGCGTAAALQSSPAPGHDARNVG
                     MASGGGGGDIGTSNCSEADFLATATPVKGDPGSFIVAYGNRSDKTCTINGGVPNLKGVD
                     MSNSPIEDLPVEDVRLPDAPKEFTLQPGQSAYAGIGMVLADSGDPNAHVLTGFQSSLPD
                     MSEAQPVNVLGDGNVKFAAKYLRVSSLVSTADELR"
     CDS             complement(77729..79984)
                     /codon_start=1
                     /note="ORF R2"
                     /product="probable exodeoxyribonuclease V"
                     /protein_id="AAG23283.1"
                     /transl_table=11
                     /translation="MLSVEKGRESATWTAVLEGTLERITFANEESGYTVARIDTGRGGD
                     LVTVVGALLGAQPGEALRMRGRWGSHPQYGRQFHVDDYTTVLPATVQGIRRYLGSGLIK
                     GIGPKLAEKIVDHFGVAALDVIEQEPARLIEVPKLGPKRTKLIADAWEEQKAIKEVMIF
                     LQGVGVSTSLAVKIYKQYHDDAIRTVKEEPYRLAGDVWGIGFKTADTIAKAVGIPHDSP
                     QRVKAGLQFTLSESTGDGNCYLPENELIAEAVKILAVDTGLVIECLAELVTEEGVVREE
                     IPTDDDEVPTVAIYLVPFHRAEVALANQLSRLLNTSADRMPVFADVDWHKALDWLRRAT
                     GAELAEAQERAVKLALTEKVAVLTGGPGCGKSFTVRSIIALAQAKKAKVILAAPTGRAA
                     KRLTELTGHDAATVHRLLQLQPGGDAAYDRDNPLDADLVVVDEASMLDLLLANKLAKAI
                     APGAHLLLVGDVDQLPSVGAGEVLRDLLAPGTPIPHVRLNEVFRQAAESGVVTNAHRIN
                     AGDYPLTHGLTDFFLFHVEESEPTAELTVDVVARRIPRKFRFNPRTDVQVLAPMHRGPA
                     GAGALNQLLQEAITPAREGLPERRFGGRIFRVGDKVTQIRNNYDKGANGVFNGTQGVVS
                     ALDNEAQTMTVRTDEDEDIDYDFTELDELVHAYAVTIHRSQGSEYPCVVIPLTTSAWMM
                     LQRNLLYTAVTRAKKVVVLVGSKKALGQAVRTVGSGRRHTALDHRLRRGGTGSRPAA"
     misc_feature    complement(78635..78637)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(78842..78844)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
ORIGIN
        1 gatctccatg aagctcaacg taggcacgga cggtcaggtg gactgggtga tcgcccgcga
       61 cctgctggcc gacgggctga tcgccgaggc aggcgaaggc gatgtgcgga tcggccctcg
      121 acggggtttt ccggggttgg tcgtgatcga gatgagctcg ccgtcggggc aggcctcctt
      181 cgaggtgaat gctgaccagc ttgcggactt cttgaacgac acctacgacg tggtcgaacc
      241 tggtgatgaa caccggtgga tgaacgtcga cgaggtgctg agccagctgc tctcgccaac
      301 ctgtaatggc ccagctctcc cgaagcgccg cacgccaaag cgctggctgc gggacctggc
      361 ggcgctgaac accgccacgc tgtgtctccg agctccagct ggaccacgtc ggtgccgtgc
      421 gcccggctcg gtcaggccga aggtgctgat cttctccagg cgcgccatcg gcgcaggaag
      481 cgctgcttct gctcccgccg cagtaccgtc gtgtcatggc cacggacagc ttcgattcct
      541 cgaagctaca ggcggccgtg gcatcgagcg tcgcgtcgtg cgtctcggaa gtcagccgag
      601 acgtctacac gcacctgatt accgaggctc cgcagttgcg agccgatgag atcgtcctca
      661 gcattctacg gacgagtgtt gaggaaaata tcgccacatt gccgcacgtt ctcgaattcg
      721 agattccgtt gggatattcg ccgggtcctg ctgcggtgtt ggagtatccg cgacgactgg
      781 cgaaacattt ccatcaacgc gctgatcagg gccaaccgca tcgggcactt ccgcttcctg
      841 tagtgatgcc tcgacgagat ccgccgccaa tgcgccgacg aggccgtatc cgcagcgacc
      901 acgcaacgaa tgctcgcaac cagcttcggc tacatcgacc gcgtcacgga gcagatcgcc
      961 gaaacctacc agctcgaacg ggaccgctgg ctcctggcga cgggacggcc gtgaggtctc
     1021 tgcggcatcc gcatagcgtc ttctcccgct gaggcacatg aggtgttgcg cgcggtcgtt
     1081 tccggcagtc gcacggcatt cgtcctagct gcgggcaatt gagggagcga agatttagag
     1141 gagtgtggcc acgcggacca agccggcgag tgctcgggag cggctgtggg gcggccaggc
     1201 gatgactgtc gtcacgtccg gcgcgtctag aaccggtacg gcggcgaggc cttcgagcag
     1261 gttgacgcga ctggattcgg gcatgaccac ggtagtgcgg ccgagtgcga tcatttggaa
     1321 cagttgcgtc tggttgcgta cttccacgcc ggggccatct ggatagacgc cgtcggggcc
     1381 gggccagcgc gcaagcggga gatccggcag tgagctgaca tccgccatcc gtacatgggg
     1441 ctcgctggca agcggatgcg aggtcggaag aatggcgact tgttgctcgg tgttcagaat
     1501 ttcgatgtcg agttcggccg tcgggtcgaa gggttgatgc aacagcgcca cgtcggcccg
     1561 gccgtcatgc agcgttttct ggggctggga ttcgcagagc agcaggtcga cggccacggc
     1621 tcccggctcg gcggcgtacg cgtcgagcaa cttcgccagc agctcaccgg aggcgccggc
     1681 cttggcagcc aggactagcg agggctggct cgtcgcggca cgctgggtgc gtcgctcggc
     1741 tgctgccagc gcgccgagga tcgcccggcc ttcggtcagc agcattgccc cggcttcggt
     1801 gagcgagact ttgcggctgg tgcgttgcag caacacgact ccgagtcgtt gctcgagctg
     1861 ggcgatcgtc cgcgacagcg gcggctgggc gatgcccagg cgctgggcgg cccggccgaa
     1921 gtgcaactcc tcggcgactg caacgaagta ccgcaactcc cgcgtctcca tccgtcgagc
     1981 ctaccgctga ttcatatcag ctgggtatcg gtgtgagacc tagatggtgt tggttccccg
     2041 ccggtttcgg gccacgctag aaagcatgag cgaacagacg attgcactgg tcaccggcgc
     2101 aaacaaggga atcggatacg agatcgcggc cgggctcggc gcgctggggt ggagcgtcgg
     2161 aatcggggca cgggaccacc agcgcgggga ggatgccgtg gcgaaattgc gtgcggacgg
     2221 cgtcgatgcg ttcgcggtat ccctggacgt gacagacgac gcgagcgtcg cggctgctgc
     2281 ggctctgctc gaggagcgcg ccggccggct cgatgtgctg gttaataacg ccggcatcgc
     2341 cggggcatgg ccggaggagc cctcgaccgt cacaccggcg agcctccggg cggtggtgga
     2401 gaccaacgtg atcggcgtcg ttcgggttac caacgctatg ctgccgttgc tacgccgctc
     2461 cgagcgcccg cggatcgtca accagtccag ccacgtcgct tccctgacct tgcaaaccac
     2521 gccgggcgtc gacctcggcg ggatcagcgg agcctactca ccgtcgaaga cgttcctcaa
     2581 cgcgatcacc atccagtacg ccaaggaact cagcgatacc aacatcaaaa tcaacaacgc
     2641 ctgccccggc tacgtcgcga ccgaccttaa cggcttccac ggaaccagca cgccggcaga
     2701 cggtgccagg atcgccattc ggctcgccac gctgccagac gacggcccga ccggaggcat
     2761 gttcgacgac gccgggaatg tgccctggtg aggcgctcag tcggcgatgg tgcaatcgaa
     2821 gtcggagagg ctcgctgcga ccgggtacgc cgaacaacac ctgttcctgt gggtacggat
     2881 gtcggccttc gccgtctcgg tcattgacaa cctgtacttc gggcgccgtt accgccggtg
     2941 cgccgcggtt gcctggcgac actgggccag ccgtggctca ccggcggctt aggtcaggcg
     3001 tgggcggttg ccagcatggc gggtgcggct ttgcgtaggt cgggtaggcg catccggcgc
     3061 gggagccggt cgagttcttc gccgatggcc ggtgctttgg ggctgctcag gagccgaaca
     3121 cctcccagcc gcaggtgccg ggctgaaccg agtggttctc gtcggctcgg atcacaacgt
     3181 ctgccggaac agctgcggcg aggtggtcgc agattcgagg cgggatcgtc ctcggcgacc
     3241 ttgccgacga tcgcggctag ggcccagggc ttcgtcgacc tggttggcac ctagatcacg
     3301 acggtcaaaa cttgccggca tcagagacga tcgaagtgat cccgggtcac gtcggcttat
     3361 cggtcgagtg agtcccgggg cctgcccagc caggtcttgc gtcgttgttc cgggctcagt
     3421 tgcggattcc gacgaacagg cctcggccgt tcggtgctcc aggaaggtat tccgcgcgga
     3481 tccctgcgtc ttcgagcgcg gcggtgtact cgtcctcagt gaacagcgag aggatttcga
     3541 actctgtgaa gtcccggatc ccggtgggtt cggcgactgt gtagcggacg gtcatccggc
     3601 tcgtacggcc ctccaggacc gagtgcgata gccggctgat cacccgctcg ccgtggtgcg
     3661 cgacggctcc ggtgacgaac ccgtcgatga acttgtcggg aaaccaccag ggttcgatga
     3721 ccgcgactcc accaggggcc aggtgccggg ccatgttccg cgtcacgcgt cgcaggtcgt
     3781 caacggtccg catgtaagcc gcggtaaagc acaggcaggt gatgacgtcg aatggctcgc
     3841 cgaggtcgaa atcgcggatg tcaccgatgt gaatcggtac ctcagggact cgtctgatcg
     3901 cgatctcccg catcgcatcg gacagttcaa gccccgcgac cttcgcgtat tcggcacgga
     3961 atcgctctag gtgcgccccg gtcccacagg cgacgtcgag tagggactgt gcttcgggca
     4021 gcctggtgcg tacgagctgg actacttccc cggcctcggc tgcccagtcc cggccacgcg
     4081 cggagtggat cgcgtcgtag atgtcggcat gatctgggct gtataccgag gaggtttctg
     4141 cgaatgtgtc gctcacgcgc gacatcctca ctttcggagt ggtgatcttt ggctgatgtg
     4201 gtgttcgacg gccttctgga actcgtcagc caccgtgcgc acctcggcgt cgtcaaggct
     4261 tgggtgcagt ggtagcagga gtgttctgcg gcaggcgtcc tccgcagaag gcagcttgca
     4321 gtccgcgcgg tagatgggga ccttgtgcag gggcgggtag cggtagctcg tgtagatgcc
     4381 gcgttccagc atttgctgcg ccacctggtc gcggatctcc ggagccagct ggacccagta
     4441 gaagtagtgt gacgagacgt gcccatccgg tagcgtcggc ggtaggagga cacccggcac
     4501 atcggaaagc aaccggtcgt actgcgtagc gatttctcta cgcctgttga tgaattctgg
     4561 cagtttgcgc agctgcacgc tgccaagcgc tgccgtcatg tcgttcccga tcagccgctg
     4621 gccgatgtct tcgacgcgaa tatcccacca gcggttggaa gacttggccg aatcgaatcc
     4681 gctcatctgc tcaagaccgt ggtaggcgag tcgtcttgcg cggtgcgcca gctccggatc
     4741 cgccgcgtag aacatgcccc catccccggt gaccaggatc ttcatcgcat cgaaactcca
     4801 cgtggccagg tcaccaaagg ttccgcaagc ggtgccgtgc acggacgatg ccaccgcgca
     4861 ggcggagtcc tcgatgagca tgaggccctt ttcacggcag aaatcggcga tcgcggtgac
     4921 ttctcccggc gatcctccat agtggagcag caatacggcc ttggtcgccg gcgtgatggc
     4981 cctcgccaca tcatccagcg tggggttcaa cgtccggggg tcgacgtcgc agaacaccgg
     5041 gcgggcaccg gaggatgcga tggcgttggc cgccgccacg aagcttatcg aaggaagtac
     5101 cacgtcgtcg cctgggccga ggtcgagcac ctgcacggta aggaacagcg cggcagtccc
     5161 cgagttgagg aacacgacct gttcgggatc cactcccagg tggtgggcga attcggcctc
     5221 gaacgtccgg gtgcgcggcc cgagcccgat ccagttggag gcgaacacct ccgcgatcgc
     5281 gtcgagttct tcggtgccga ggatcggctg gtgcaggttg atcacgttgc tgaaatcctc
     5341 cgagatgccg ccatgctgga tgctaggaac tcttggccac gaattcagcg attgattcga
     5401 cgacgtagtc gatcatttgg tccgttatgc ctgggtagac gccgacccag aaggttcggt
     5461 cggtgacgat gtcgctgttg gtgagcgcgt cggcgatccg gtaccgcacc tgctcgaagg
     5521 ccgggtgccg ggtgatgtta ccgccgaaca gcagtcgggt gccgatgttg cgggattcca
     5581 ggaagttcac cagggcggca cgggtgaacc cggcgtccgc actgatggtg atcgcaaacc
     5641 cgaaccagct cgggtcgctg tgcggtgtgg ctaccggcag cagcaggccc ggcaacccgg
     5701 acagcccttc gcgcaaccgt cgccagttac ggcggcgtgc cgacccgaat gcggaaatct
     5761 tgctcaactg gctcagcgca agtgcggcct gcaggtcggt ggtcttgagg ttgtaaccga
     5821 cgtgggagaa cgtgtacttg tggtcgtagc ccggtggaag ggtaccgagg tggtagtcga
     5881 acctcttgcg gcaggtgttg tccacgccgg gctcgcacca gcaatcccgt ccccagtcac
     5941 gcagcgactc gatgatgcga gccaattcca ggctgccggt caacacgcag ccaccctcgc
     6001 cgctggtgat gtgatgggca ggatagaagc tgaccgttgt caggtcgccg aaggttccgg
     6061 tcagccgtcc ccggtaggtg gatcccaccg catcacagtt gtcttcgacg aggaacagct
     6121 cgtgttcttt tgcgatctcc gcgatttcgt cagcggcgaa ggggttgccc agggtgtgcg
     6181 ccagcatgat ggctcgcgtc cgttccgtga cggcggcctt gatgcggtct ggcgttgcgt
     6241 tgtaggtgcc cagttccacg tcgacgaata ccgggacgag tccgttttgg accgccggat
     6301 tgatcgtcgt ggggaagccg accgccgcag tgatcacttc gtcgccgggc cgcagtcgtg
     6361 cctcgccgag tttgggggag gtaagcgaac tcagtgccag gagattggcc gacgaaccgg
     6421 agttgacgag atgagccttg cggaggccga agaagcgggc gaactcgctc tcgaatcgcc
     6481 gtgcattccc gcccgcggcg atccggagct ccagcgcggc ttccaccagt gccacccggt
     6541 cgtcctcgtc gagcacggcg cccgatggcc ggatcggcgt cgatccagcc acgaaggtcg
     6601 gggattcctg ttcgcggtgg taatcgcgta cggatgccaa tatccggtcc ttggcatccg
     6661 gcaccatctc agtagcggta gcgcaagtgt cgtcacacga agtcactctg gcgcgccctt
     6721 tccccagcgc tctggttttc cggctctgca tgcaggcgac gatcagtctt cgcgccttgc
     6781 cttcaggaga tgagcgatgc ccgtggcgaa tcgcgttatg acgtcccagc gggacagtgt
     6841 gctgtctcgg cgccttacac cttcctgccc tggttcgatg cggtgcggga catcaggaca
     6901 gcggagcaag gagaagcgct cattgactca gaaatcctcg atctacccgg cacacccgac
     6961 tcggtagagc ccaggctagc gggaacgacc tgctcgcgct tgtcaagatc gctaccatca
     7021 cctggaaggc ctaagatttg gcttgcgaaa gcggcgtttc ccgggggata tcagagattt
     7081 ctgtgattct tggcatgctt cccgggtgtt caattgcgat cggagagttc atgcgtgtcc
     7141 tgttcacccc gctgccggcg agttcgcact tcttcaacct ggtgccgttg gcgtgggcgt
     7201 tgcgtgccgc ggggcacgag gtccgtgtcg ccatctgccc gaatatggtg tcgatggtca
     7261 ccggagcagg actcaccgcg gttcccgtcg gcgacgagct cgacctcatc tccttggcgg
     7321 ccaagaacga actcgttctc ggcagcgggg tctcgttcga cgagaagggg cggcatccgg
     7381 aactcttcga cgagctgctg tcaatcaact ccggcagaga cacggacgcc gtggagcaac
     7441 tccaccttgt ggatgaccga tcgctggacg atctcatggg gttcgccgag aaatggcagc
     7501 ctgatctcgt tgtgtgggac gctatggtgt gttcggggcc agttgtggcg cgagcgctcg
     7561 gcgcacgaca cgtgcggatg ctcgtcgccc tcgatgtgtc ggggtggctg cggtccggtt
     7621 tcctcgaata ccaggaatcg aagccgcctg agcagcgcgt cgacccgctc gggacgtggc
     7681 tgggagcgaa gctcgccaag ttcggagcca cgttcgatga agagatcgtg acgggccaag
     7741 cgaccataga tccgattcca tcctggatgc gcctgcctgt ggacttggac tacatctcga
     7801 tgcgtttcgt gccgtacaac ggtccggcgg tgttgccgga gtggttgcgc gaacgaccga
     7861 cgaagccgcg cgtctgcatc acgcgcgggc tgaccaagcg gcggctgagc agggtgaccg
     7921 aacagtacgg ggagcaaagt gaccaggaac aagcaatggt ggaaaggttg ttgcgcggcg
     7981 cggccaggct cgacgtcgag gtgatcgcca ccttgtctga cgacgaagta cgggagatgg
     8041 gggagttgcc ctcgaacgtc cgggtccacg aatacgtacc gctcaacgaa ctgctggagt
     8101 cgtgttcagt gatcatccat catggctcga cgacgacgca ggaaaccgcc acggtcaacg
     8161 gcgtaccgca gttgattctc cctgggacct tctgggacga atctcgtagg gcggagctcc
     8221 tagccgatcg gggagccggt ctggtcctcg accccgcgac gtttaccgaa gacgacgtgc
     8281 gaggtcagct ggcccgcctg ctcgacgagc cgtcgttcgc tgccaacgcg gcgctgatcc
     8341 gccgtgaaat cgaggaaagt cccagcccgc acgacatcgt tccacgtctg gaaaagctag
     8401 ttgccgaacg tgagaaccgc cgcactgggc agtctgatgg ccatccgtga gcaacgtgtg
     8461 gccggaaaca tggacgccgg ggtttggcag gtgttcatcg ctgttgcgtc gactcggatt
     8521 ccgccgtgac cgggacgatg ccaggcgagt cccgaagtca gattcttgtc cagaatcgtc
     8581 caatggggtg ttgatctccc cagaggtttg cgctccaacc gatttccgac gaggatcgtg
     8641 gcgcccgctg agcaacgact accgtgcggt cgagacatac cgctgtgcgc caggagcgaa
     8701 ggtgggttgc ccgatcaccg tgctggtggt agatgccgag ccgaaggtca ccttggatga
     8761 ggcggaagcc tggcgagagc acaccgaggc cgtggccgac gtccgtgtct tctccggcgg
     8821 gcatttcttc atgaccgaac gccaggacga ggtgctcgcg gtccttacgg gcggatcgct
     8881 tcgatgatcc tcgccaggcc gctggaccag accgcgacgc ccctgggagc cggcgtgcac
     8941 atcgtcacgg cagtgaggga ttgggcatga gcagttctgt cgaagctgag gcaagtgctg
     9001 ctgcgccgct cggcagcaac aacacgcggc ggttcgtcga ctctgcgctg agcgcttgca
     9061 atggcatgat tccgaccacg gagttccact gctggctcgc cgatcggctg ggcgagaaca
     9121 gcttcgagac caatcgcatc ccgttcgacc gcctgtcgaa atggaaattc gatgccagca
     9181 cggagaacct ggttcatgcc gacggtaggt tcttcacggt agaaggcctg caggtcgaga
     9241 ccaactatgg cgcggcaccc agctggcacc agccgatcat caaccaggct gaagtaggta
     9301 tcctcggcat tctcgtcaag gagatcgacg gcgtgctgca ctgcctcatg tcagcaaaga
     9361 tggaaccggg caacgtcaac gtcctgcagc tctcgccgac ggttcaggca actcggagca
     9421 actacacgca ggcacaccgt ggcagcgttc cgccctatgt ggactacttc ctcgggcggg
     9481 gccgcggccg cgtgctggta gacgtgctcc agtctgaaca ggggtcctgg ttctaccgga
     9541 agcgcaaccg gaacatggtg gtggaagtcc aggaggaagt gccagtcctg ccagacttct
     9601 gctggttgac gctcggccag gtgctggctc tccttcgtca ggacaacatc gtcaacatgg
     9661 acacccggac ggtgctgtct tgcatcccgt tccacgattc cgccaccgga cccgaactag
     9721 ccgcctcgga ggagcccttc cgacaggcgg tggccaggtc gctctcgcac ggcatcgatt
     9781 cgtcgagtat ctccgaggcg gtcggttggt tcgaggaagc caaggcccgc taccgcttgc
     9841 gggcaacgcg cgttccgctg agcagggtcg acaagtggta tcgcaccgat accgagatcg
     9901 cccaccagga cggcaagtac ttcgcggtga tcgcggtgtc ggtgtccgcg accaatcgtg
     9961 aggtcgccag ctggacgcag ccgatgatcg aaccgcgaga acaaggtgag atcgcactgt
    10021 tggtcaagcg gatcggcgga gtgctgcacg gtttggtcca cgctcgggtg gaggctgggt
    10081 ataagtggac tgcggaaatc gctcccacgg tccagtgcag tgtggccaac taccaaagca
    10141 ccccgtcgaa cgactggccg ccgttcttgg acgacgtgct caccgccgat cccgaaaccg
    10201 tgcggtacga atcgatcctg tccgaagaag gcggtcggtt ctaccaggcg cagaacaggt
    10261 accggatcat cgaggtgcat gaggacttcg cggcacgacc tcccagcgac ttccggtgga
    10321 tgactttggg acagttgggc gagctgctcc ggagcaccca cttcttgaac atccaggcgc
    10381 gcagcttggt cgcctccctg catagcttgt gggcgttggg gcgatgacca gctcgatgcg
    10441 aaagccggtg cgcatcggtg tgctcgggtg cgcttccttc gcgtggcgac ggatgctgcc
    10501 cgcgatgtgc gacgtggccg aaacagaggt ggtggcggtg gcgagccgtg atccggcgaa
    10561 agccgaacgg ttcgcagcgc gattcgaatg cgaggcggtg ctgggttacc agcggctcct
    10621 ggagcggccg gacatcgatg ccgtctacgt gccgttgccg cctggcatgc atgcagagtg
    10681 gatcggcaag gcgcttgagg cagacaaaca cgtgcttgcg gagaaaccgc tgacgacgac
    10741 ggcgtccgac accgctcgcc tggtcgggct ggccaggagg aagaacctgc tgctgcggga
    10801 gaattacctg ttcctccacc acggccggca cgacgtggtc cgcgacctgc tgcaatccgg
    10861 ggagatcggt gagctccggg agttcaccgc cgtgttcgga attccgccgc ttcccgacac
    10921 ggacatccgc tatcgcaccg aactcggtgg cggagcgttg ctggacatcg gtgtctatcc
    10981 cgcccgtgcc gctcggcact ttctcctcgg tccgctcacg gttctcggcg caagctcgca
    11041 cgaggcccag gagtcgggcg tcgacttgtc gggcagcgtg ctgctccaat cggaaggtgg
    11101 caccgttgcc cacctcggat acggtttcgt gcaccactac cgcagcgcgt acgagctgtg
    11161 ggggagtcgt gggcgaatcg tcgtcgaccg ggcgttcacg ccgcccgccg agtggcaggc
    11221 cgtgatccga atcgagcgga agggcgttgt cgacgagttg tccttgccag cggaagatca
    11281 ggttcgcaag gcggtcaccg ccttcgcacg cgacatcaga gcagggacag gcgtggacga
    11341 ccctgcggtg gccggagatt cgggcgaatc gatgatccag caggccgcgc tggtggaggc
    11401 gatcggtcag gcccgtcggt gcgggtccac atagccgccc ggcatccgcg ggtagtagtt
    11461 cgcctcgaag cctgaccggg catccggaag ccagcgggga agccgctgga gaggctcacc
    11521 gccatccgct cacctggcat ctcgcggacc gctgatcgcg gacggctcgg agaagtgctc
    11581 gtcgaaccac gagacgacca ctcgcgagct ggccagggcg gcgggaaagt gagccaatcc
    11641 ggagagcgga tgccaccgca ctggcgtacc cgccgcgcgg tagctgtccc ggagtcgctc
    11701 gccgaatgcg aacggaacga tctcgtcgtc cgtgctgtgg tagacgagcg tggggaccac
    11761 cgggccaccg ttcctacctg cgacgctttc ggccagtcgt gcgcgccatc gaggttgctc
    11821 gaaaaggccg gaagtgtcga ggaagtcgct cagctcgcgg ccgaggaagc gggtgacgag
    11881 ctccggtgca ccgagctcgc gcacttgatc aacggcggta cgacccgctt cggtgagaag
    11941 ctcgtcgaat ggcagatcgg ggtaggcagc ggcatgcccg accaggccgg ccagcaccgg
    12001 cccggtgaac accccgtcat ttcggtggat gatgtccagc agatcgatcg gcaccgcacc
    12061 tgcggccgca gcgcggattc gcagttcagg tgcgtaggtg gggtgcagtt cgccggcgaa
    12121 ggccgacgct tgcccaccct gcgcatagcc ccagatgccg accgggcagt cggtcgtcag
    12181 gccggagccc ggtagccgtt gcgcagcgcg ggcggcatcg agcatggcgt gtccctgcgc
    12241 cctgccgacg gtgtaggtgt gggttccagg agtaccgagg ccttcgtagt cggtgatgac
    12301 cacggcccac ccgcggtcga gggccacggc gatcagctcg gtctccggct cggttccggt
    12361 tcgaagcagg tacgacgggg caacttggct accgaggccg tgggtgccca ctgcgaaagt
    12421 gatgatgggg cgatcttcgc gcggccacgg gatgttcggc accagaacgg tgccggagac
    12481 ggcgttcggc atgccaaggg cggagttgga ccggtagagg atttgccagg ccttggctgc
    12541 gacgggttcg cccgtgccgc gcagtgccga gacgggccgg gccctgagga gcgtgcccgg
    12601 gacacccggc ggtagcggcg tcggcggtcg gtagaaggga tcatccgcgg gtgcccgcag
    12661 atcgtcgccg accaggctgg cgtgctcgga ggccatcagg actgcttctt tcgagcctgc
    12721 aggagcatga aacccatgct ttcctcgttt ctggcgtaat ccggatgttt ccggtattcc
    12781 gcaaccgcgg cgatcagctg tgctggtccc ggtccgtgct tcgccgcgat gtctcccaag
    12841 tagcgttgct ggtaggtgcc gacagccgca ggctcgacgc cggcgagctc atcgagtttc
    12901 cggagcaact cgtcgacgta ccaggagacc atgcacctgg tctgtgccgt gaggtcggtg
    12961 acttcgagaa tctcgaaccc ggcttcgctg accagcgccg tgaagctgtt caaggtatgg
    13021 gcggtcgtgc ccgtccaaac cgccgcgtac tcttccggga gtcgaacccg agtgatgatg
    13081 tctccgagga cgaaccggcc gccgggttcc aggattcggt ggacctcgcg gatcgcggcg
    13141 gcctggtcca cgatctgcac gacggactgc atcgcccatg cggcctgaaa gaaaccgtcc
    13201 gggtagggca gctgggcgcc gtcgactaga tcgaactcaa gactgccggc cagtccggtc
    13261 tcgttggcga gcctggtggc ggcggcgaga tgctgggcgt tcacggtgat tccggtgact
    13321 cgaacgccgc tggcgcatgc cgcacggact acgggctgcc cattgccgca gcccaggtcg
    13381 aacaggtgcg ctccgggacg gagcgcggcc ttgtcgatga acaggtcggt cagttggtcg
    13441 gcagcatccg accacggtgt ggcaccggca tcctcccgat acccgcccgc ccagtaaccg
    13501 tggtgcaggg gacgcccgtg cgccaacgca tcgaagatgg actccacctg atccgcggtc
    13561 ggaaatgcct gtgtgttcgc ccctctgctg ttcactcgtc ctccgcgctg ttcacgtcgg
    13621 ccaggtgcaa tatgtcgtcc agactccttg gcacccaagc aggaacgccg ccttcggcgt
    13681 tgacgccttt ctccaggaac gcgatgttgt ggtaggtgtg gaggccgacc aaattgcgtt
    13741 ccaggtagct cggctcgtac gagcccgcat gcggctgctc ctcgtgctga acgccttcca
    13801 acaggttctt gagcaggctg accgtggtgc cgggtgcggc cgggcactgc gcctgcccgc
    13861 cgaatccggg agcataggtc gtccacagat cctcgatcac gtatacgcca ccgctgcgca
    13921 accgggggaa cagcgtttcc agggatgtgc gcacgtgtcc gttgatgtgg ctgccatcgt
    13981 cgatgatgat gtcgaacggt ccgtacttgt cgtcaacggc ggccagctcc tcgggcttgc
    14041 tctggtcggc gcggacggtg cagagcctct gctggtcgag gaaggacttg tcgaaaacgt
    14101 ccatcccgaa cacgaggccg cggtggaagt agcgcttcca catcttcagg gattcgccgc
    14161 cgccaccgtc gaagttgtag ccaccgacac cgatctccag gatgcgcacc gggcgatcac
    14221 ggaactcgcc gaggtgtcgc tcgtatagcg gggtgaacca gtgcaggccg ccccacttgt
    14281 ccgtgcggta gtgggaggcg agcaagttga ggtcgggacg tcggtgcccg cagccggcga
    14341 ccactgcgga gatggcctgg aagccatcgg acagttccga cggaccgggt atcgaaccgg
    14401 atgtggtggt tcggaggaag ttggtgctcc gggcgccgac ggccctggga gctcctgggc
    14461 cgaacaactc ggcgatgaga tcggtgagct cgtaaccgat ccgcagcggg acgtctccga
    14521 ccggtcgttg ctcggccttg atcagctcac cggactgtag cgtcaggacg aagtcaacgg
    14581 tctcgcctcg gtgggtgatc tggaccgcga cctcggtccg ttcgatgtcg ggggccggtt
    14641 ccgcgcggaa gaggatctcg tcgatcagca cgggtgcgat cctggcgagt ccgagttcgg
    14701 tggtcaggtc ggccaggctc gccgcactgg atccggcggc gaggatgatg cgttccacgg
    14761 tttcgatctc gtgcgttgtg gacatcgtga tgagctcctc atggctgacc gggtgaaagc
    14821 cgtgccggcg gtttgatcga caggccgtgc tggaagatgt tctgcggatc ccaccgcgct
    14881 ttggcccgct gcagccgcgg gtagttgtct ttgtagtaca ggtcgtgcca ggcaacaccg
    14941 gaggtgttcc acaatggatc ggccaagtcg gtgtccgggt agttgatgta ggagccgtcg
    15001 acacgggtac ctggcaccgg aactccgccg gtttcggcgt acatctcgcg gtagaaaccg
    15061 cgaatccagg tcagatgccg ctcgtcctcg gcgggctccg accagttcgt gacgaacagc
    15121 gctttgagaa ccgagtcgcg ctgagcgagt gcggtggccg acggagccac ggcattcgcc
    15181 ataccgccgt aaccgagcag caacagcgcc gccgcagggt tgtcgtatcc gtagacggtc
    15241 agccgccggt aaaccgtggc tagttgagct tcggacagcc cggtgcgcaa gtaggcggct
    15301 ttgaccttgg tccgttgcat gcccggttcg ccgccttcgg cgatcgcccc ggccacctgg
    15361 gtcgatcgca accacggcag ggtttcccgc agcccttcgg ctggagtcac gccgacctgg
    15421 gcgttgatcg ccgacaggtg ttcggccagg gtgcgttccg cgttcggatc cgtgccgtcc
    15481 aggtgaacgt tcagcgtgac gtagccagct tgccggtgtg cgcagacgag cgtgctgaac
    15541 aacccgagtt gcgtggattc aggcgcgctg tgctgctcgt accaattgcc gaagttctgt
    15601 aggagcacgg cgaatgactg ctctgtcagt tcgtgccacg gccagtggaa cgatcggagc
    15661 agcactgtcg cgggcggccg tggcaggagc tctgcggcgt cggtgctgac cacgtccggc
    15721 gttcggagcc aaaacctggt gacgatcccg aagttgccgc caccgccacc ggtgtgcgcc
    15781 caccacaagt cgtgaccggc gcccgtggag ttccggtcgg cctcgacgat gtgcacttca
    15841 ccggcctggt cgaccacgac gacctcgacg ccttgaaggt agtcgacgac cgaaccgaat
    15901 cggcgcgaca gcgggccgta tcccccgccg aggatgtgcc cgcctgcgcc caccccggga
    15961 catgcgccgg tcgggatcgt cacgccccag ttcttgaaca gggttcggta cacctgcccg
    16021 agggcggcgc ccgcctcgat cgcgaatgcc ccgcgcgtgc tgtcgtagta cacgcggttg
    16081 agctcggaga ggtcgacgag cactcggatc gccgggtccg caacgagatt ctcgaagcag
    16141 tgcccgccgc tgcggacccc tacccgcctg ccggtgcgca cggcgtcggc gacggcgtgc
    16201 acgacgtctt cggcggagct ggcgatgtgg atgcgttcgg gttttccggt gaaacggggg
    16261 ttgtgcccga cgacgaggtc cggataacga ggatcgtcgg gctcgacggt gatctctgtt
    16321 cctggggttc gacgattcat gggtgccggg tcatggaatt cgggcaccgc ccctcctttt
    16381 ctgactggtc cactttgttc gcccgcagcc gagatcatct acgcgtccgg gtgattatct
    16441 gtgtgtttca gctcatacgt gaaacccggt cgcctccgcc ggctctactt tgtggatcga
    16501 tatcgcggtg cgcatggtgc cgtatgcgct ggaaccgaaa aggtgatgac ttaccatgag
    16561 tgagatcgca gttgccccct ggtcggtggt ggagcgtttg ctgctcgcgg cgggtgcggg
    16621 cccggcgaag ctccaggaag cagtgcaggt ggccggactg gacgcggtgg ccgacgccat
    16681 cgtcgacgaa ctcgtcgtac gctgcgatcc gctgtcgttg gacgagtcgg tgcgaatcgg
    16741 cctggagatc acttctggcg ctcagctggt ccggagaacc gttgagctcg atcacgcagg
    16801 cctgcggctc gcggcggtcg ccgaagcagc tgctgttctc cggttcgacg cggtggatct
    16861 gctggaaggg ctcttcggcc cggttgacgg caggcggcac aacagccgtg aagtccgctg
    16921 gtcggacagc atgacgcagt tctcgcccga ccagggcctc gccggcgcgc agcgcctgct
    16981 ggcgttccgg aacagggtgt ccaccgcggt gcacgccgtg ctggccgcag ccgccaccag
    17041 gcgcgcggac ctcggtgcgc tggcagtccg ctacggatcc gacaaatggg cggacctgca
    17101 ctggtacacc gaacactacg agcaccactt ctcccgattc caggatgccc cggtgcgagt
    17161 gttggaaata ggaatcggtg gttatcacgc acccgaactc ggtggtgctt cgctgcgcat
    17221 gtggcagcgg tacttccggc gaggtctcgt ttacgggctg gacattttcg agaaagccgg
    17281 gaacgaaggg caccgagtgc gaaagctgcg aggtgaccag agcgatgcgg aattcctgga
    17341 agacatggtg gcgaagatcg gcccgttcga cattgtcatc gacgacggca gccatgtcaa
    17401 cgaccacgtc aagaaatcct tccaatccct gtttccgcac gtccgcccag gtggtttgta
    17461 cgtcatcgag gatctccaga cggcgtactg gcccggctac ggcggtcgcg atggggaacc
    17521 cgcggcccag cgcacctcga tcgacatgct caaagaactg atcgacggcc tgcattatca
    17581 ggagcgcgaa tcgcggtgcg ggaccgagcc ctcctacacg gaacggaacg tggcggccct
    17641 gcacttctac cacaacctgg tattcgtgga gaaagggctc aacgctgaga ctgccgcgcc
    17701 ggggttcgtg ccccggcaag cgctcggcgt cgagggcggc tgagccgttc accagctgcg
    17761 gcgccagtag gcgcccgtgc cgtcgatgtc gtggatgggt tccgtgatcc cgagttccgc
    17821 gcggaacccc ttcaccgcgt cctggcagga cggcagaaaa tagtcgtcga tgatgacgaa
    17881 tccgcccggc gagagcttcg ggtacaggtt ccgcaatgag tccattgtgg attcgtagag
    17941 gtcgccgtcg agtcgtagca cggcgagttc ctggatgggg gcggtgggca aggtgtcccg
    18001 gaaccagccg gggaggaacc tgacctgttc gtcgagcagc ccgtagcggg cgaagttctg
    18061 ccggacggtc tcaagcgata cgccaagcac gtcgttgtac tcgtgcagcg ccatagcctg
    18121 gtccgcttgg tggtcttgcg cagagctttc cggcattccc tggaaggaat ccactaccca
    18181 gacggtacgt ccggtatctc cgaatgcctg gagaaccgcg cgcatgaaga tgcatgcgcc
    18241 gccccgccag acaccggtct cggcgaaatc cccgggaaca ccgtctgcga gcacggcttc
    18301 cacgcagtgc tggaggttgt ccagccgctc cagaccgatc atcgtgtgcg cgacagttgg
    18361 ccagtccgtg cctttggccc gagcggcctg cctgtagtcg gtgttgtcct gccaggcgtt
    18421 cggatgcggc cgatcactgt aaatcgtgtt ggtgagtacc ttcttgagca ggtccaggta
    18481 cagcgcgttc tgggagggca tcggttctcc ggatccagct gttctcgggt gactagttca
    18541 tcaggcacgg atggccgcag tgttctccag tgtccgcacc agcgcggcgg gatggggcat
    18601 ggccgtgatc tcgtcgctga gtttgattgc cgcagaagcg aagccggtgt cgccgagcac
    18661 cgttgcgatt gagtcggtga actgttcgtg gtcggactgg gcctgctcat ccggcaagca
    18721 gatgcccgcc ccggcagcgg cgaggttgcg cgcgtagtcg aactggtcga agtactgggg
    18781 aagcacgagt tgcgggatgc cgagtcgggt cgcggtgaat gccgttcccg agccgcccgc
    18841 gcagatgacc agctcgcagg tacgcaggaa caggttgagc gggaccgatt cggcgatccg
    18901 ggcgttgtcg ggtaggtcgg tgagaagtgc ccggtgctcg gggggaacgg cgatcacggc
    18961 ctcgacgccg ggcaactcgg tggcagccgc tactgcgcgc agcagcggag ccggcccggt
    19021 ggcgttcagc accatgcggc ccatgcagat gcagacccgc cgtgctgagg tgcgcgccgc
    19081 gccccatgcc gggaatgcgc cgcttccgtt gtacggcacg tactggaccg gtgcgccttg
    19141 cggcgcgtcg cttgcttgca ggctcggcgg acagggatcg aggatgagct cgggagtggg
    19201 caggccggtc agtccgtggt gccggcacac cgggtcaagc aactcgtggg ctcgatcgct
    19261 gaaggggcct gcggtggggt cgactcccca gcggtgcagc acgaccggca ggtcgagcaa
    19321 tccgccgagc acccggccga tcagcgcgca gacgtcgacc aacagcactg acggtcgcca
    19381 ggcctcggcc agtcgaaggt attcggggag ctgatcgagc gagctttgcg cgacattgga
    19441 cgcggtctgc tcccacagtt gccggcctgc ctcggtgtcg cgctgaccga acgccggatt
    19501 gggaaagcgc agctgcgtgg ttccacccgt atcgccggtc ctgtcgttcc cgcggatccc
    19561 ggccgtggtg agacctgcac catgcgcggt cgcctgcagc tctggtggtg cggcgatcag
    19621 gacctcgtgc ccggatgctt gcagcgccca gcacagcggc accattgcca tgagatgcgt
    19681 cggatagggc aagggaacga cgagtacgcg catacttcgg accccagtct ctttcccccg
    19741 attagcgcag cagcccctac tcccattggc caggatttgg aaaatgcgct gcgtatgtcg
    19801 atcgccgttg acgtccaacg gacttccggc ggcaacaata gtgtgtcacg gcaggaatgt
    19861 cacgcgacca tcgaagatct ttgggtcgcc gcacctggtt tcacgcgaac gagtgaaatg
    19921 cgcgagctcc gctcgatcgg ggtgggccgg acctgtacgg tgatcaccgt tggttctgcg
    19981 gggattcatg gggaagattt gcgctggctg tttgcctcct ggccggatag ttatagtcgg
    20041 taccgccgca tgcggcggta accgcgaatt aactgacggc tagtttgccg tcttttctct
    20101 ctgtgtgttt cctgctcggt tccagaaaat tacgagaagg tgaacgttgc agagatcagg
    20161 cataccggtg ttgccaggtg gcgcaccaac atcgcagcag gttgggcaga tgtatgacct
    20221 ggtcacgccg ttgctgaact cggtcgcggg cggcccctgc gccatccacc acggctactg
    20281 ggagaacgac gggcgggctt cctggcagca ggccgccgac cggctcaccg accttgtcgc
    20341 cgaacggacc gtgctcgatg gcggcgttcg actgctcgat gtggggtgcg gtaccggaca
    20401 accagcgctg cgcgtcgcgc gcgacaacgc gatccagatc accggcatca ccgtcagcca
    20461 ggtgcaagtg gccatcgccg ctgattgcgc acgcgaacgc ggactaagcc accgggtgga
    20521 cttctcgtgc gtcgatgcca tgtccctgcc gtacccggac aatgctttcg acgccgcctg
    20581 ggccatgcag tcgctgttgg agatgtccga accggaccgt gccatccggg aaatccttcg
    20641 agtactcaaa cccggtggca tcctcggcgt caccgaggtc gtcaaacgag aagcgggcgg
    20701 cgggatgccg gtgtccgggg acaggtggcc gaccggcctt cggatctgcc tggctgagca
    20761 acttctggaa tcgctgcgtg cagcggggtt cgagatcctc gattgggagg acgtgtcgtc
    20821 gaggacccgg tacttcatgc cgcagttcgc cgaagagctc gctgcgcacc agcacgggat
    20881 cgcggacagg tacgggccgg ctgtcgccgg ctgggccgcc gcggtctgcg attatgagaa
    20941 atatgcccac gacatgggct atgcgattct gacggcgcgg aagccggtcg gctgagggcg
    21001 cgccgcaatt cgatgacgtt catgcgccgt gtcggagaat cgccggtggc ggcgccagca
    21061 gaggctgaac ttactggtgg tgtgtccagg aatcggaggg gcagtaccga atgagcgaag
    21121 ccgggaacct gatagccgtc atcggactgt cctgccgcct accccaggcg cctgacccgg
    21181 cttccttctg gcggttgctg cgcaccggaa cggacgccat caccacggtc ccggaagggc
    21241 ggtggggcga cccgttgcct ggtcgggatg cgcccaaggg cccggaatgg ggtggtttcc
    21301 tggctgatgt cgactgcttc gatcccgagt tcttcgggat ctcgccgcga gaagcggcaa
    21361 ccgtggatcc ccagcagagg ctggctctgg agctcgcctg ggaggcactc gaagacgccg
    21421 gtatccccgc cggcgagctg cgcggtactg ccgccggtgt gttcatgggg gcgatctctg
    21481 acgactacgc cgccctgctg cgcgagagcc cgccggaagt ggctgcgcag taccgcctca
    21541 ccggcaccca tcgaagcctg atcgccaacc gcgtgtccta tgtgctcggc ctgcgcgggc
    21601 caagcctgac ggtggattca ggtcagtcct cgtccctggt cggcgtgcat ctcgccagcg
    21661 agagcctgcg acggggtgag tgcacgatcg cactcgccgg cggcgtgaac ctcaacctgg
    21721 ccgccgagag caacagcgct ctgatggact tcggcgcgct ctccccggac ggtcgctgct
    21781 tcaccttcga tgtgcgggcg aacggttacg tccgtggtga gggcggcggc cttgtcgtgc
    21841 tgaagaaggc cgatcaggcg cacgccgatg gcgaccggat ctactgcctc atccgcggca
    21901 gcgcggtcaa caacgatggg ggcggtgccg ggctcaccgt tccggcggcg gacgcccagg
    21961 cggagctgct gcgccaggca taccggaacg cgggcgtcga cccggccgcc gtgcagtatg
    22021 tcgagctcca cggcagcgcg accagggtcg gggatcccgt cgaagcagca gccctcggag
    22081 ctgtcctggg ggcggcgaga cggcccggcg acgagctgcg tgtggggtcg gcgaagacca
    22141 acgtcggcca tctggaagca gcggcgggcg tcaccgggtt gctgaagacc gcactcagca
    22201 tctggcaccg cgaactgccg ccgagtcttc atttcaccgc ccccaacccg gaaatcccgc
    22261 tggacgaatt gaacctacgc gtccagcgtg atctgcggcc gtggccggag agcgaggggc
    22321 cgctgctggc cggcgtcagc gccttcggaa tgggaggcac gaactgccac ctggtgctct
    22381 ccggcacgtc ccgggtggag cgacggcgca gtggacccgc tgaggcgacc atgccgtggg
    22441 tcttgtcggc cagaacaccg gtcgcattgc gtgcgcaggc ggcgcgcttg cacacgcacc
    22501 tcaatacggc cggtcaaagt ccgttggacg tcgcctactc actggcgacc actcgatccg
    22561 cgctaccgca ccgggccgcg ctggtcgcgg acgacgaacc gaaactgctc gccgggttga
    22621 aggccctcgc tgacggcgac gacgcgccca cgctgtgcca cggcgcgact tccggcgagc
    22681 gggcagcggt cttcgtcttt cccggacagg gcagccagtg gatcgggatg ggtaggcagc
    22741 tgctcgaaac ctccgaggtt ttcgcggcgt cgatgtcgga ctgcgccgac gcattggcgc
    22801 cacacctgga ttggtccctg ctggatgtgc tgcgcaacgc ggccggcgct gcgcaccttg
    22861 accacgacga tgtcgtccag cccgcgctgt tcgccatcat ggtctcgctc gcggagctct
    22921 ggcgttcgtg gggcgtgcgt ccggtggcgg tcgtcgggca ctcgcagggg gagatcgcgg
    22981 cggcctgcgt cgccggggcc ctgtccgtcc gcgatgccgc cagggtggtg gcggtgcgca
    23041 gcaggcttct gacggcgctg gccggcagtg gcgcgatggc ctcgttgcag catcccgccg
    23101 aagaggtgcg gcaaatcctg ttgccctggc gcgatcggat cggcgtggcg ggggtgaacg
    23161 gaccgtcgtc gaccctggtg tcaggggacc gggaggcgat ggcggaactg ctggccgagt
    23221 gcgcagaccg agagctccgg atgcgccgga ttcccgttga atacgcctcc cattcgcctc
    23281 acatcgaggt tgtccgggat gagctgctgg ggctgttggc gccggtcgaa cccaggacgg
    23341 gaagcatccc gatctattcg acgacgaccg gggacctgct ggaccggccg atggacgccg
    23401 actactggta ccgcaacctt cgtcaaccgg tgctgttcga agcggccgtc gaggccctgt
    23461 tgaagcgggg gtacgacgca ttcatcgaga tcagcccaca cccggtgctg actgcgaaca
    23521 tccaggaaac cgccgtgcga gcagggcggg aggtagtggc gctcgggaca ctccgccgcg
    23581 gcgaaggtgg catgcggcag gcgctgacgt cgctggccag agcacacgta cacggagtgg
    23641 ccgcggactg gcacgcggtc ttcgccggta ccggggcgca gcgggtcgac ctgccgacgt
    23701 acgcctttca gcgacagcgc tactggctgg acgcgaagct tcccgacgtc gccatgcccg
    23761 agagcgacgt gtcgacggcg ttgcgggaaa agctgcggtc ttcgccgagg gcggacgtgg
    23821 actcgacgac cctcacgatg atccgggcac aggcagccgt ggtcctcggc cactccgatc
    23881 cgaaagaggt ggacccggat cggacgttca aggacctggg cttcgattcc tcgatggtgg
    23941 tcgagctgtg cgaccgccta aacgccgcca caggtctgcg actcgcaccg agcgtcgttt
    24001 tcgactgtcc tacgccggac aagctcgccc gccaggtacg gacgttgttg ttgggcgagc
    24061 cggctcccat gacgtcacac cggccggact ccgatgcgga cgagcctatc gccgtgatcg
    24121 ggatgggctg tcggtttccg ggtggggtgt cctcgcccga ggagttgtgg cagttggtcg
    24181 ccgctgggcg ggacgtcgtg tccgagttcc cggctgaccg aggttgggac ctggagcgtg
    24241 cggggacatc gcacgtgcgc gccggcgggt tcttgcatgg cgccccggat tttgaccccg
    24301 ggttcttccg gatttcgccg cgcgaggcgt tggcgatgga tccacagcag cggttgctgc
    24361 tggaaatcgc ctgggaagca gtcgaacgag gcgggatcaa cccgcagcac ctgcacggaa
    24421 gtcaaaccgg ggtcttcgtc ggcgcgacct ccctggacta cgggccacgc ctgcacgaag
    24481 cgtccgagga ggcggccggg tacgtgctca ccggcagcac cacgagtgtg gcgtcgggtc
    24541 gggttgcgta ttcgttcggg ttcgagggcc ctgcggtgac ggtggatacg gcgtgttcgt
    24601 cgtcgttggt ggccctgcat ttggcgtgtc agtcgttgcg ttcgggtgag tgtgatctgg
    24661 cgttggccgg tggtgtgacc gtgatggcca cgccggggat gttcgtggag ttttcgcggc
    24721 agcgtggttt ggcgccggat gggcggtgca agtcgttcgc ggaggccgcc gacggcaccg
    24781 gctggtccga gggtgctggc ctggttctac tggagcggtt gtcggatgcc cggcggaatg
    24841 ggcatgaggt gctggcggtt gttcgtggta gtgcggtgaa tcaggacggt gcgtcgaatg
    24901 gtttgaccgc gccgaatggt tcgtcgcagc agcgggtgat tgcccaggca ttggcgagtg
    24961 cggggttgtc ggtgtccgat gtggatgctg tggaggcgca tgggacgggc acgcggcttg
    25021 gtgatccgat cgaggcgcag gcgctgatcg ccacctacgg ccagggccgg cttccggaac
    25081 ggccattgtg gttgggctcg atgaagtcga acatcggtca cgcgcaggca gctgcgggga
    25141 tagccggcgt catgaagatg gtgatggcga tgcggcacgg gcagctaccg cgcacgttgc
    25201 acgtggatga gccgacttct ggggtggatt ggtcggcggg gacggttcaa ctccttacgg
    25261 agaacacgcc ctggcccggg agtggtcgtg ttcgtcgggt gggggtgtcg tcgttcggga
    25321 tcagtggtac taacgcgcac gtcatcctcg aacagccccc gggagtgccg agtcagtctg
    25381 cggggccggg ttcgggctct gtcgtggatg ttccggtggt gccgtggatg gtgtcgggca
    25441 aaacacccga agcgctatcc gcgcaggcaa cggcgttgat gacctatctg gacgagcgac
    25501 ctgatgtctc ctcgctggat gttgggtact cgctggcgtt gacacggtcg gcgctggatg
    25561 agcgagcggt ggtgctgggg tcggaccgtg aaacgttgtt gtgcggtgtg aaagcgctgt
    25621 ctgccggtca tgaggcttct gggttggtga ccggatctgt gggggctggg ggccgcatcg
    25681 ggtttgtgtt ttccggtcag ggtggtcagt ggctggggat gggccggggg ctttaccggg
    25741 cttttccggt gttcgctgct gcctttgacg aagcttgtgc cgagctggat gcgcatctgg
    25801 gccaggaaat cggggttcgg gaggtggtgt ccggttcgga tgcgcagttg ctggatcgga
    25861 cgttgtgggc gcagtcgggt ttgttcgcgt tgcaggtggg cttgctgaag ttgctggatt
    25921 cgtggggggt tcggccgagt gtggtgttgg ggcattcggt gggcgagttg gcggcggcgt
    25981 tcgcggcggg tgtggtgtcg ttgtcgggtg cggctcggtt ggtggcgggt cgtgcccggt
    26041 tgatgcaggc gttgccgtct ggcggtggga tgctggcggt gcctgctggt gaggagctgt
    26101 tgtggtcgtt gttggccgat cagggtgatc gtgtggggat cgccgcggtc aacgctgcgg
    26161 ggtcggtggt gctctctggt gatcgggatg tgctcgatga ccttgccggt cggctggacg
    26221 ggcaagggat ccggtcgagg tggttgcggg tgtcgcatgc gtttcattcg tatcggatgg
    26281 atccgatgct ggcggagttc gccgaattgg cacgaaccgt ggattaccgg cgttgtgaag
    26341 tgccgatcgt gtcgaccttg accggagacc tcgatgacgc tggcaggatg agcgggcccg
    26401 actactgggt gcgtcaggtg cgagagccgg tccgcttcgc cgacggtgtc caggcgctgg
    26461 tcgagcacga tgtggccacc gttgtcgagc tcggtccgga cggggcgttg tcggcgctga
    26521 tccaggaatg tgtcgccgca tccgatcacg ccgggcggct gagcgcggtc ccggcgatgc
    26581 gcaggaacca ggacgaggcg cagaaggtga tgacggccct ggcacacgtc cacgtacgtg
    26641 gtggtgcggt ggactggcgg tcgttcttcg ccggtacaag ggcgaagcaa atcgagctgc
    26701 ccacctacgc cttccaacga cagcggtact ggctgaacgc gctgcgtgaa tcttccgccg
    26761 gcgacatggg caggcgtgtc gaagcgaagt tctggggcgc cgtcgagcac gaagatgtgg
    26821 aatcgcttgc acgcgtattg ggcattgtgg acgacggcgc tgctgtggat tccctgagaa
    26881 gcgcccttcc ggtgttggcc ggttggcagc gaacccgcac caccgagtcc attatggatc
    26941 agcggtgtta ccgaattggc tggcggcagg tagccggact cccgccgatg ggaactgttt
    27001 tcggtacctg gctggtcttc gcgcctcatg gctggtccag cgaaccggag gtggtggact
    27061 gcgttacggc actgcgggca cgtggtgcct cggtggtgtt ggtggaagct gatcccgacc
    27121 cgacctcctt cggcgaccgg gtacgaaccc tgtgttcggg ccttccggat cttgttggcg
    27181 tgttgtcaat gttgtgcttg gaagaatcgg tccttccggg attttctgcg gtgtcacggg
    27241 gttttgcgtt gaccgtggag ttggtgcggg ttttgcgggc agctggtgcg actgcccggt
    27301 tgtggttgct gacgtgtggt ggcgtgtcgg tgggagatgt accggttcgt ccagcgcagg
    27361 ccctggcgtg ggggttgggg cgtgttgtgg ggttggagca tccggactgg tggggcggct
    27421 tgatcgatat tccggtcttg ttcgacgaag acgctcaaga gcggttgtcg attgtgctgg
    27481 caggtctcga tgaggacgag gtcgcgatcc gtcctgacgg catgttcgcg cgtcggttgg
    27541 tacgccacac tgtctcagct gatgtgaaga aggcgtggcg ccccagggga tcggtgctgg
    27601 tgacgggcgg cacgggtggt ttgggggcgc acgttgctcg ctggctggcc gacgccggag
    27661 ccgaacatgt ggcgatggtg agtcgacgcg gcgagcaggc accgagtgct gagaagttgc
    27721 ggacggaact ggaggatctg ggtacccggg tgtcgatcgt gtcatgcgat gtgaccgatc
    27781 gcgaggcgct cgccgaagtg ctgaaagccc ttccggctga aaacccgttg accgcggtag
    27841 tgcatgcggc aggcgtgatc gagactggtg atgcggcggc aatgagcctg gctgatttcg
    27901 atcacgtgtt gtccgcaaag gtggccggtg ccgcgaatct ggatgccttg ttggccgatg
    27961 tggaattgga cgcgttcgtc ttgttctcat cggtgtcagg agtttggggc gctgggggac
    28021 acggggctta cgcagcggcg aatgcctatc tggatgcgct cgcggaacag cgtcggtcgc
    28081 gagggctggt cgcgactgcg gtggcctggg ggccgtgggc cggcgagggc atggcctccg
    28141 gagaaacagg agaccagctg cgccgatacg gcctttcccc aatggctccg cagcacgcca
    28201 tcgccggaat ccggcaggcc gtggaacagg acgaaatttc cctggtagtg gccgatgtcg
    28261 attgggcacg tttcagcgcg ggattgctgg cggctaggcc gcggccgctg ctgaacgaac
    28321 tggccgaggt caaggaactc ctcgtcgatg cccagcccga ggcgggagtc cttgccgacg
    28381 cgtcgttgga atggcggcag cgattgtccg cggcaccgag gccgacacag gaacagctga
    28441 tcctggagct ggtacgcggc gaaaccgctc tggtgctggg acaccccggg gcagcggccg
    28501 ttgcatcgga acgagccttc aaggacagcg gattcgactc gcaggccgcg gtcgaactcc
    28561 gcgttcggct caatcgagct accggcctcc agttgccatc gacaattatc ttcagccatc
    28621 ccacgcctgc ggaactggct gcggagctgc gggcgaggct tcttcccgag tccgcaggag
    28681 caggcattcc cgaggaggac gaggcgcgaa tcagagcggc actgacgtcg atcccgttcc
    28741 cggccttgcg cgaggcaggc ttggtgagtc cgctgctcgc acttgccgga cacccggtcg
    28801 actccggtat ctcctcggac gatgcggccg cgacctcgat cgatgcgatg gatgtagccg
    28861 gcctcgtcga agcagcgctg ggcgaacgcg agtcctgaga ccgccgacct gggagatgac
    28921 ggtgaccacc agttacgaag aagttgtcga ggcactgcga gcatcgctca aggagaacga
    28981 acgcctccgg cgcggcaggg atcggttctc cgcggagaag gacgatccca tcgcgatcgt
    29041 ggcgatgagt tgtcgttatc ccggtcaggt ctcctcgccg gaggacctgt ggcaactggc
    29101 tgccggcggt gtggacgcga tctccgaagt tccgggggat cgcggatggg acctggatgg
    29161 cgtgttcgtt ccggactccg atcgtcctgg cacgtcgtat gcctgcgcgg gcggttttct
    29221 tcagggcgtg tcggagttcg acgcgggttt cttcgggatt tcgccgcgtg aggcgctggc
    29281 gatggatccg cagcagcggt tgctgctgga agtcgcgtgg gaggtcttcg agcgggctgg
    29341 gctggagcag cggtcgacac gcggttcccg cgttggcgtg ttcgtcggca ccaatggcca
    29401 ggactacgcg tcgtggttgc ggacgccgcc gcctgcggtg gcaggtcatg tgctgacggg
    29461 cggtgcggca gcggttcttt cgggccgggt tgcgtattcg ttcgggttcg agggtcctgc
    29521 ggtgacggtg gatacggcgt gttcgtcgtc gttggtggcg ttgcacctgg cggggcaagc
    29581 actgcgggcc ggtgagtgcg accttgccct tgccggtggc gtcacggtga tgtcgacgcc
    29641 gaaggtgttc ctggagttct cccgccaacg gggtctcgcg ccggatgggc ggtgcaagtc
    29701 gttcgcggcg ggtgcggatg gcactggatg gggtgagggt gccggactgt tgttgctgga
    29761 gcggttgtcg gatgcccggc ggaatgggca tgaggtgctg gcggttgttc gtggtagtgc
    29821 ggtgaatcag gacggtgcgt cgaatggttt gaccgcgccg aatggttcgt cgcagcagcg
    29881 ggtgattacc caggcgttgg cgagtgcggg gttgtcggtg tccgatgtgg atgctgtgga
    29941 ggcgcatggg acgggcacgc ggcttggtga tccgatcgag gcgcaggcgc tgatcgccac
    30001 ctacggccgt gatcgtgatc ctggccggcc gttgtggttg gggtcggtca agtcgaacat
    30061 cggtcatacg caagcggcgg cgggtgtggc tggtgtgatc aagatggtga tggcgatgcg
    30121 gcacgggcag ctgccacgca cgttgcacgt ggaatcgccg tcgccggagg tggattggtc
    30181 ggcggggacg gttcaactcc ttacggagaa cacgccctgg cccaggagtg gtcgtgttcg
    30241 tcgggtgggg gtgtcgtcgt tcgggatcag tggtactaac gcgcacgtca tcctcgaaca
    30301 gcccccggga gtgccgagtc agtctgcggg gccgggttcg ggttctgtcg tggatgttcc
    30361 ggtggtgccg tggatggtgt cgggcaaaac acccgaagcg ctatccgcgc aggcaacggc
    30421 gttgatgacc tatctggacg agcgacctga tgtctcctcg ctggatgttg ggtactcgct
    30481 ggcgttgaca cggtcggcgc tggatgagcg agcggtggtg ctggggtcgg accgtgaaac
    30541 gttgttgtgc ggtgtgaaag cgctgtctgc cggtcatgag gcttctgggt tggtgaccgg
    30601 atctgtgggg gctgggggcc gcatcgggtt tgtgttttcc ggtcagggtg gtcagtggct
    30661 ggggatgggc cgggggcttt accgggcttt tccggtgttc gctgctgcct ttgacgaagc
    30721 ttgtgccgag ctggatgcac atctgggcca ggaaatcggg gttcgggagg tggtgtccgg
    30781 ttcggatgcg cagttgctgg atcggacgtt gtgggcgcag tcgggtttgt tcgcgttgca
    30841 ggtgggcttg ctgaagttgc tggattcgtg gggggttcgg ccgagtgtgg tgttggggca
    30901 ttcggtgggc gagttggcgg cggcgttcgc ggcgggtgtg gtgtcgttgt cgggtgcggc
    30961 tcggttggtg gcgggtcgtg cccggttgat gcaggcgttg ccgtctggcg gtgggatgct
    31021 ggcggtgcct gctggtgagg agctgttgtg gtcgttgttg gccgatcagg gtgatcgtgt
    31081 ggggatcgcc gcggtcaacg ctgcggggtc ggtggtgctc tctggtgatc gggatgtgct
    31141 cgatgacctt gccggtcggc tggacgggca agggatccgg tcgaggtggt tgcgggtgtc
    31201 gcatgcgttt cattcgtatc ggatggatcc gatgctggcg gagttcgccg aattggcacg
    31261 aaccgtggat taccggcgtt gtgaagtgcc gatcgtgtcg accttgaccg gagacctcga
    31321 tgacgctggc aggatgagcg ggcccgacta ctgggtgcgt caggtgcgag agccggtccg
    31381 cttcgccgac ggtgtccagg cgctggtcga gcacgatgtg gccactgttg tcgagctcgg
    31441 tccggacggg gcgttgtcgg cgctgatcca ggaatgtgtc gccgcatccg atcacgccgg
    31501 gcggctgagc gcggtcccgg cgatgcgcag gaaccaggac gaggcgcaga aggtgatgac
    31561 ggccctggca cacgtccacg tacgtggtgg tgcggtggac tggcggtcgt tcttcgccgg
    31621 tacgggagcg aaacaaatcg agctgcccac ctacgccttc caacgacagc ggtactggct
    31681 ggtgccatcg gattccggtg atgtgacagg tgccggtctg gccggggcgg agcatccgct
    31741 gttgggtgct gtggtgccgg tcgcgggtgg tgacgaggtg ttgctgaccg gcaggatttc
    31801 ggtgcggacg catccgtggc tggccgaaca ccgggtgctg ggtgaagtga tcgttgcggg
    31861 caccgcgttg ctggagatcg ccttgcacgc gggggaacgt cttggttgtg aacgggtgga
    31921 agagctcacc ctggaagcac cgctggtcct gccggagcgc ggggcgatcc aggttcagct
    31981 gcgagtgggc gcgcccgaga attccggacg caggccgatg gcgctgtatt cacgccccga
    32041 aggggcggcg gagcatgact ggacgcggca cgccacgggc cggttggcgc caggccgcgg
    32101 cgaggcggct ggagacctgg ccgactggcc ggctcctggc gcgctgccgg tcgacctcga
    32161 cgaattctat cgggacctcg cagagcttgg gctggagtac ggcccgatct tccaagggct
    32221 caaggcggcc tggcggcaag gggacgaggt gtacgccgaa gccgcgctgc cgggaacgga
    32281 agattctggt ttcggggtgc atccggcact gctggacgcg gctctgcacg caacggctgt
    32341 ccgagacatg gatgacgcac gcttgccgtt ccagtgggaa ggtgtgtccc tgcacgccaa
    32401 ggccgcgccg gctttgcggg tccgcgtggt cccggctggt gacgatgcca agtccctgct
    32461 ggtttgtgat ggcaccggtc gaccggtgat ctcggtggac cgactcgtat tgcggtcggc
    32521 tgcggcccgg cggaccggtg cgcgccgaca ggcccatcaa gctcggttgt accggttgag
    32581 ctggccaacg gttcaactgc cgacatccgc tcagccaccg tcctgcgtgc ttctcggcac
    32641 ctcagaagtg tccgctgaca tacaggtgta tccggacctc cggtcgttga cggctgcgtt
    32701 ggatgccggt gccgaaccac ccggcgtcgt catcgcaccc acgccccccg gcggtggacg
    32761 aacagcggat gtccgggaga cgactcggca tgcactcgac ctggtacaag gctggctttc
    32821 cgatcagcga ctcaacgaat cccgattgct cctggtgaca cagggagcag tggccgtgga
    32881 gccgggcgaa cccgtgaccg atctggcgca ggccgcgctc tggggactgc tgcggtcgac
    32941 gcagaccgaa caccctgatc gcttcgtcct cgtcgatgtg cctgagcccg cgcaactcct
    33001 ccccgcgctg ccgggggtgc tggcctgcgg cgaacctcag ctcgcgttgc gacgtggcgg
    33061 cgctcatgcg cccagactgg ctggactggg cagcgatgac gtcctgcccg tgccggacgg
    33121 caccgggtgg cgattggagg ccacgcgccc gggaagcctg gatgggttgg cattggtgga
    33181 cgaaccgacg gccacggcac cgctgggtga cggtgaggtc aggattgcga tgcgcgcggc
    33241 cggggtgaac ttccgggatg cgctcatcgc gctcggtatg tatcccggtg tggcatcgct
    33301 gggcagtgag ggcgccgggg tcgtggtgga gaccggcccc ggcgtcaccg gcctggcacc
    33361 cggcgaccgc gtgatgggaa tgatcccgaa ggcgttcggg ccgctcgcgg tcgccgacca
    33421 tcgcatggtg acgaggattc ccgctggttg gagcttcgcg cgggccgcat cggtgccgat
    33481 cgtctttctc accgcctact acgcgctggt tgatctcgcc gggttgagac caggggagtc
    33541 gttgctggtt cattcggccg ccggtggggt ggggatggcc gcgatccaac tcgccaggca
    33601 cctcggtgca gaggtgtacg ccaccgctag cgaggacaag tggcaagccg tggagctgag
    33661 ccgagaacac ctcgcttcgt cgcggacgtg cgatttcgag cagcagttcc tcggggcaac
    33721 cggcggacgc ggcgtcgacg tcgtgctcaa ctccctcgcc ggggagttcg ccgatgcgtc
    33781 tctgcgaatg ctgccgcgcg gtggccgttt cctggagttg gggaagacgg atgttcgtga
    33841 ccccgtcgag gtcgccgatg cgcatccggg cgtgtcttac caggctttcg ataccgtaga
    33901 ggcaggcccg cagcgaatcg gcgagatgct tcacgagctg gtggagttgt tcgagggacg
    33961 cgtgctggag cccctgcctg tcacggcttg ggacgttcgg caggcgcccg aggcgctacg
    34021 gcacctgagc caagcgcggc atgtgggaaa gctggtgctc accatgcctc cggtgtggga
    34081 cgccgcaggc acggttctgg ttaccggcgg aacgggagca cttggcgcag aggtcgcccg
    34141 gcacctcgtg atcgagcgcg gggtgcgaaa cctggtcctc gtcagcaggc gcggtcccgc
    34201 agccagtggc gctgctgagc tcgtggcgca actgacggcc tacggtgccg aggtttcctt
    34261 gcaggcttgc gatgtcgccg atcgtgagac cttggcgaag gtgcttgcca gcatcccgga
    34321 cgagcatccg ttgaccgccg tggtgcacgc ggctggtgtt ctcgacgacg gagtgtccga
    34381 atcgctcacc gtggagcggc tggaccaggt tctgcgcccg aaggtcgatg gcgcgcggaa
    34441 tctgctcgag ctgatcgacc cggacgtggc cctcgtgttg ttctcgtcgg tgtcgggtgt
    34501 gctcggcagc ggtgggcagg gtaactacgc ggcggccaac tccttcctcg acgcattggc
    34561 gcagcaaagg cagtcgcgcg gcctaccgac gagatcattg gcctgggggc cctgggcgga
    34621 acatggcatg gccagcacct tgcgcgaagc cgagcaggat cgattggcgc gatctgggtt
    34681 gctgccgatc tcgaccgagg aggggttgtc ccagttcgac gccgcgtgcg gcggcgcgca
    34741 taccgtggtg gcgccggttc gattcagccg cttgtccgac gggaacgcga tcaagttctc
    34801 cgtcctgcaa ggtttggtcg ggccgcatcg cgtcaacaaa gcggcgactg cggatgatgc
    34861 cgagagcctc cggaaacggt tgggacgctt gccggatgca gaacaacatc ggattctgct
    34921 ggacctcgtc cgcatgcatg tggcggcagt gctcggattc gccggttctc aggagatcac
    34981 cgcggacggc acgttcaagg tgctgggctt cgactcgttg accgtggtcg agttgcgcaa
    35041 ccggatcaac ggggcgacgg ggctgcgact gcccgccacc ctggtgttca actacccgac
    35101 gccggatgcg ctcgccgcgc acctcgtcac cgcgctgtcc gcagaccgcc tggccgggac
    35161 attcgaggaa ctcgacaggt gggcggcgaa cctgcccacg ctggccaggg atgaggccac
    35221 gcgggcgcag atcaccaccc ggctacaggc gatcttgcag agcctggcgg acgtgtccgg
    35281 cggaaccggc ggcggctccg tgccggaccg gctcagatcg gccacggacg acgagctttt
    35341 ccaactcctc gacaacgatc tcgaacttcc ctgatgcctc agccggagcc ttcgcaactt
    35401 cctggaggga aacgccacat gtcgaatgaa gagaagctcc gggagtactt gcggcgtgcg
    35461 ctcgtggatc tgcaccaggc gcgcgagcgg ctgcacgagg cggagtcggg agagcgggaa
    35521 cccatcgcga tcgtggcgat gggctgccgg tacccgggtg gggtgcagga cccggaaggg
    35581 ctgtggaaac tggtcgcctc cggtggcgac gccatcggtg aattccccgc tgatcgtggt
    35641 tggcacctcg acgagctcta cgatcccgac ccggatcagc ccggaacctg ctacacccgg
    35701 cacggcggct tcctccacga cgccggcgag ttcgacgcgg gattcttcga catcagcccc
    35761 cgtgaggcgc tcgcgatgga cccgcagcag cggctgctgc tggaaatctc ctgggagacc
    35821 gtcgaatccg ctgggatgga cccgaggtcc ttgcggggga gccgcaccgg ggtgttcgcg
    35881 ggattgatgt acgagggcta tgacaccggc gcccaccggg caggagaagg tgtcgaaggc
    35941 tatctcggaa ccggcaatgc gggaagcgtc gcctctggtc gggttgcgta tgcgttcggg
    36001 ttcgagggcc cagcggtgac ggtagacacg gcgtgctcgt cgtcgttggt ggcgctgcat
    36061 ttggcgtgtc agtcgttgcg gcagggcgag tgtgatctgg cgctggccgg tggagtgacg
    36121 gtgatgtcga cgccggagag gttcgtggag ttctcccgtc agcgtggtct cgcaccggat
    36181 gggcggtgta agtcgttcgc ggcggctgcg gatggaaccg gttggggtga gggtgccggt
    36241 ttggtgttgc tggagcggct gtcagacgcc aggcggaacg ggcatcgggt actggcggtt
    36301 gttcgtggta gcgcggtgaa tcaggacggt gcgtcgaacg gattgacggc cccgaacggg
    36361 ctggcccagg agcgggtcat tcagcaggtg ctcacgagtg cggggctgtc ggcgtccgat
    36421 gtggacgctg tggaggcgca tggaacgggt acgcggcttg gtgatccgat cgaggcgcag
    36481 gctctgatag ccgcctatgg acaggatcgg gaccgggacc ggccgctgtg gttggggtcg
    36541 gtcaagtcca acatcggtca tacgcaggcg gctgcgggcg tcgctggtgt gatcaagatg
    36601 gtcatggcga tgcggcacgg ggagctgccg cgcacgttgc acgtggacga gccgaattcg
    36661 cacgtggact ggtcggctgg tgcggtccga ctcctgaccg agaacatccg ctggccaggg
    36721 acgggtacgc gccgcgctgg agtgtcgtcg ttcggggtaa gcggtaccaa cgcacacgtc
    36781 atcctcgaac acgacccgct cgccgtgacc gagaacgagg aagcagcgca gtccccagca
    36841 cctgggatcg tgccctgggc gttgtccggg cggtcgtcga cggcgctgcg ggcccaggcc
    36901 gaacggctgc gcgagctgtg cgagcagacc gatcccgacc ccgtcgatgt cggtttctca
    36961 ctggccgcca cgcgcacggc ttgggagcac cgagcggtgg tgcttggtcg ggacagcgct
    37021 acgttgcgct ccgggcttgg cgttgttgcc agcggtgaac cagcggtcga tgtcgttgag
    37081 gggagcgtcc tggacggcga ggtcgtcttc gtcttccccg gtcagggctg gcagtgggcc
    37141 ggtatggcag tcgacctgct ggacgcttcg ccgacgttcg cgcgccacat ggacgagtgc
    37201 gccaccgcgc tgcggaggta cgtggactgg tcgttggtcg acgtgctgcg cggagcggag
    37261 aactccccac cgctggaccg ggtggacgtg ctccagcccg cgtccttcgc ggtgatggtg
    37321 tcgctcgccg aggtgtggcg ttcctacggg gtgaggccgg cggccgtcgt cggccacagt
    37381 caaggcgaaa tcgccgcggc ctgcgcagcc ggggtgctgc cgctggagga tgcggccagg
    37441 cttgtcgcat tgcgcagcag agcgttgaag ggactttcgg ggcggggtgg catggcgtcg
    37501 ctggcctgcc ctgcggatga ggtcgcggca ttgttcgcgg gatcgggcgg ccgtctggaa
    37561 gttgcggcga tcaacggccc gcgatcggtc gtggtgtccg gcgatctgga agcggtggac
    37621 gaactgctgg cagagtgcgc tgaaaaggac atgcgtgcac gccgtatccc cgtcgactac
    37681 gcctcgcatt cagcgcacgt ggaggtggtt cggagcccgg tgctggcggc cgccgccggg
    37741 gtgcgacacc gggacggcca ggtgccgtgg tggtcgacgg tgatcggcga ctgggtggat
    37801 ccggccaggc tggacggcga gtattggtat cggaacctcc ggcagccggt ccggttcgaa
    37861 cacgccgtgc agggcctggt cgagcgggga ttcggcctgt tcatcgaaat gagtgcgcat
    37921 ccggtgctga ccacggcggt cgaggaaacc ggtgcggagt cggagaccgc cgtggccgcg
    37981 gtaggtacct tgcgacgtga ctcgggcggc ctccggaggt tgttgcattc gctggccgag
    38041 gcgtacgtgc gcggcgccac cgtggactgg gccgtggcgt tcgggggcgc gggccgacgg
    38101 ctggacctgc cgacctaccc gttccagcgc cagcggtact ggctggacaa gggagctgcc
    38161 tccgacgagg ctcgtgcggt ctcggacccg gcggcgggct ggttctggca agccgtggcg
    38221 cgccaagacc tgaaaagcgt gtccgatgcc ctcgatctcg acgccgacgc accgctgagc
    38281 gcaacacttc cagccctgtc cgtctggcac cgtcaggaac gagaaagggt cttggcagac
    38341 ggttggcggt accgagtcga ctgggtacgg gtggccccgc agccggtccg gagaacgcgg
    38401 gaaacctggc tcctggtcgt tcccccgggc ggcatcgagg aagcgctggt cgaacggctg
    38461 acggatgcgt tgaacacgcg agggatcagc accctgcgcc tcgacgtgcc accggcggcg
    38521 accagtggcg aactcgcaac cgaactccgc gccgcagccg acggtgaccc ggtgaaggca
    38581 atcctgtcgc tcaccgcgtt ggacgagcga ccccaccccg aatgcaagga cgtcccgagc
    38641 gggattgcct tgctgctgaa cctggtcaag gcgctcggtg aagccgacct cagaattcct
    38701 ctgtggacca tcacgcgtgg tgcggtcaag gcaggccccg cagatcggct gctgcgcccg
    38761 atgcaggcgc aagcatgggg tctggggcga gtagccgcac tcgaacaccc cgagcgctgg
    38821 ggtgggctga tcgacctgcc ggattcgctg gacggcgacg tcctcacgag gctgggcgaa
    38881 gcgctcacca acggcttggc ggaagaccaa ctggcgattc gccagtcggg cgtgctggcc
    38941 cggcgactgg tacccgcccc ggcgaatcag cccgctggac gtaagtggcg cccccgaggg
    39001 agcgcgctga tcacgggcgg actcggcgcg gtgggcgcac aggtggcgag gtggttggcc
    39061 gaaatcggag ccgagcgaat cgtgctcacc agtcgacggg gcaaccaagc agcaggcgcc
    39121 gccgagctgg aagccgaact ccgggccctt ggagcgcaag tgtccatcgt ggcttgcgac
    39181 gtgaccgatc gtgccgagat gtccgcacta ctggccgagt tcgacgtcac cgcggtgttc
    39241 cacgcggccg gagtcggtcg gctgctgccg ttggcggaga ccgaccagaa cggcctggcc
    39301 gaaatatgcg cggcgaaggt ccgcggcgct caggtgctgg acgaactgtg cgacagcacc
    39361 gatctcgatg ccttcgtcct gttctcctcg ggtgccgggg tatggggcgg gggcggtcag
    39421 ggcgcttacg gcgcggcgaa cgcattcttg gacacactcg ccgaacaacg ccgagcacgc
    39481 ggtctgccgg caacctcgat ctcctggggc agttgggccg gcggcggcat ggccgacggc
    39541 gcggcgggcg aacacctgcg gcgacgcggg atacgtccga tgccggcggc gtcggccatc
    39601 ctggctctgc aggaagtact tgaccaggat gagacgtgcg tgtcgatcgc tgatgtggac
    39661 tgggaccgat tcgttcccac gttcgccgcg actcgcgcca cccggttgtt cgacgaagtg
    39721 ccggcggcga gaaaggcgat gcccgcgaat gggccggcag aaccaggcgg ctcgccgttc
    39781 gcccgcaatc tcgcggagct gccggaagcc caacgacgcc acgaactggt ggatctggtg
    39841 tgcgcccagg tggcaaccgt gctcgggcac ggcagtcgcg aggaagtcca gcccgagcgg
    39901 gcgttccgcg cgctcgggtt cgactccctc atggcggtgg atctgcgcaa tcgtttgacc
    39961 accgccaccg ggttgcgcct gccgaccaca accgtcttcg actacccgaa tccggccgcc
    40021 ttggccgctc acctgctcga ggagctggtg ggtgatgtcg cgtcggctgc ggtgaccgct
    40081 gccagcgcgc ccgcgagtga cgaaccgatc gcgatcgtcg cgatgagctg ccggtttccg
    40141 ggtggcgcgc actcgccgga agacctgtgg cggctggtcg ccgccggcac ggaggtgatc
    40201 ggcgagttcc cctccgaccg gggctgggat gcggaaggcc tttacgatcc ggatgcttcc
    40261 aggcctggaa cgacgtatgc gcggatggcg ggattcctct acgacgccgg tgagttcgat
    40321 gccgacctgt tcggcatcag cccacgtgag gcgttggcga tggatccgca gcagcggttg
    40381 gtgctcgaaa tcgcctggga agccctcgaa cgggccggaa tcgatccgtt gtccttgaag
    40441 ggcagtgggg tcggcacgta catcggcgct ggaagccgtg ggtacgcgac ggatgtgcgg
    40501 cagtttcccg aggaggcgga gggctacctg ctgacgggta cctcggccag tgtgctgtcg
    40561 ggtcgggtcg cgtattcgtt tggtttcgag ggtcctgcgg tgacggtgga tacggcttgt
    40621 tcgtcgtcgt tggtggcgtt gcatctggcg tgccagtcgt tgcgttcggg cgagtgtgat
    40681 ctggcgttgg ccggtggtgt gaccgtgatg tcgacgccgg agatgttcgt ggagttctcc
    40741 cgtcagcgcg gtttggcgcc ggatgggcgg tgcaagtcgt tcgcggagag cgcggacggc
    40801 accggctggg gcgaaggcgc gggcctgttg ttgctggagc ggttgtcgga cgcccaccgg
    40861 aatgggcatc gggtgttggc ggtggttcgt gggtcagcgg tgaatcagga cggcgcctcg
    40921 aacggactgg cggcgccgaa cggtccgtcg cagcagcggg tgatcaacca ggcactcgcg
    40981 aatgcggctc tttcggcgtc cgatgtggat gcggtggagg cacatggcac cgggaccagg
    41041 ctgggtgatc cgatcgaggc gcaggcattg atcgcaacgt atgggcaggc ccgggagcgg
    41101 gatcggccct tgtggctggg gtcggtcaag tcgaacatcg gtcatacgca ggccgcggcg
    41161 ggtgttgccg gtgtgatcaa gatggtgatg gccatgcggc acgggcagct gcccgcctcg
    41221 ctgcacgcgg atgagcccac gtcggaggtc gattggtcgt cgggggcggt ccggctcctc
    41281 gccgaacagg taccttggcc ggagtctgac cgtgttcgtc gggtgggggt ttcgtcgttc
    41341 gggatcagcg gcaccaacgc acatgtgatc ctcgaacaag ctacgaatgc gccagatagt
    41401 acagcggaga cggacaaaac agaatccgga tctactgtcg atattccggt cgttccctgg
    41461 ttggtgtcgg gaaagacgac ggattccctg cggggacaag ccgaacgagt cttgtctcag
    41521 gtcgagtccc ggccggagca gcgttcgctg gatgttgcct actcgcttgc ttctggccga
    41581 gccgcgctgg atgaacgcgc tgtcgtgctg ggtgcggacc gcggtgagct ggttgctgga
    41641 ctggcggcgt tggccgccgg tcaggaggct tctggggtga tcagcggaac tcgtgcttct
    41701 gctcggttcg ggttcgtgtt ctcggggcag ggtggtcagt ggttggggat gggcagagcg
    41761 ctctactcga agtttccggt gttcgctgct gcgtttgatg aggcttgcgc cgagttggag
    41821 gcacatctgg gggaagaccg ccgggttcgg gatgtggtct tcggttccga tgcgcagctg
    41881 ctggatcaga cgctgtgggc gcagtcgggt ctgttcgcgc tgcaagccgg cctcttgggg
    41941 ctgctgggtt cgtggggcgt tcggccggat gtggtgatgg ggcattcggt cggggagttg
    42001 gccgccgcgt ttgcggctgg cgtgttgtcg ttgcgggatg cggctcggtt ggtggccgcg
    42061 cgcgcccggt tgatgcaagc cctgccctct gacggcgcga tgttggcggt ggctgctggt
    42121 gaagaccttg ttcggccatt gctggccggt cgggaggagt ccgtgagcgt cgccgcgctc
    42181 aatgcccccg gttcggtggt gttgtcgggc gatcgggagg tgctggccag catcgtcggc
    42241 cggctgaccg agctccgagt ccggacgcgg cgcttgcggg tctcccatgc ttttcattcg
    42301 caccggatgg acccgatgtt gggcgagttc gcccagatcg ccgagtctgc ggagttcggt
    42361 aagccaacga caccgcttgt gtcgacgttg acgggtgagc tcgacagagc cgcggaaatg
    42421 agcacaccag ggtattgggt gcgccaggcg cgtgaacccg tccgtttcgc cgacggtgtc
    42481 caggccctgg cagcgcaggg cataggcacg gtcgtcgagc tcggcccgga cggaacgctg
    42541 gcggcactgg ttcgggagtg tgcgaccgag tccgatcggg ttgggcggat ttcgtcgatc
    42601 ccactgatgc gcagggagcg ggacgagacc cgttcggtga tgacagccct ggcgcatctc
    42661 cacacccgtg gtggtgaggt ggactggcag gcgtttttcg ccggtaccgg cgctaggcag
    42721 ctcgagttgc caacgtatgc cttccaacga cagcactact ggatcgagtc cagtgcgcgg
    42781 ccagcacgcg accgcgcaga catcggcgag gtggcggaac agttctggac cgcggttgac
    42841 caaggcgatc tggcaacgtt ggtcgccgct ctggatcttg gggcggacga cgacacatgc
    42901 gcatcgttga gcgatgtatt gccggcgttg tcctcctggc gaagcggact ccgcaaccgt
    42961 tcgctcgtcg attcctgccg gtaccgaatc agttggcatt cctctcggga ggtgccggcc
    43021 ccgaagattt ccggtacctg gctgttggtc gtgcccggtg ctgcggatga cggattggtc
    43081 acggctttga cgagttcact ggtcggaggc ggcgccgagg tcgtccggat cggcctgtcc
    43141 gaagaggacc cgcaccgcga ggacgtcgca cagcggctgg ccaatgcgct gacggatgcc
    43201 ggtcaactcg gtggcgtgct ttcgctgttg gggctcgatg aatcgcctgc tccgggattc
    43261 tcctgcttgc caactggttt cgcgctgact gtgcagcttc tgcgggcctt gcggaaggcc
    43321 gacgtcgagg cgcctttttg ggcggtgacg cgcggcggcg tcgcgttgga agatgtacgc
    43381 gtgtctccgg agcaggccct ggtctggggg ctgctgcgtg tcgcgggact ggagcacccg
    43441 gagttctggg gtggcttgat cgacctgcca tcggactggg acgaccgatt gggtgcccgg
    43501 ttggcgggtg tgttggcgga tggtggcgag gatcaagtcg ccattcgccg tggtggtgtg
    43561 ttcgtgcggc ggttggaacg cgctggtgcg tcgggtgccg ggtcggtgtg gcgtcctcgg
    43621 gggacggtgt tggtgacggg tggtacgggc ggtttggggg cgcatgttgc ccggtggttg
    43681 gccggtgccg gggctgagca cgtggtgttg accagccgtc gaggagcgga cgctccgggc
    43741 gctggggaat tgcgggcgga gctggaggcg ctgggtgctc gggtgtcgat tgtgccctgc
    43801 gacgtggctg atcgtgacgc agtggctgga gtgttggcag ggatcggtgg ggagtgtccg
    43861 ctgactgcgg tggtacacgc cgccggggtc ggcgaggcgg gcgacgtagt ggagatgggt
    43921 ttggcggatt ttgcagcggt gttgtcggcg aaggtgcgtg gtgcggcgaa tctggacgag
    43981 ttgctggccg actcggagct ggatgcgttt gtgatgttct cctcggtgtc gggggtgtgg
    44041 ggagccggcg gacagggtgc gtatgcggct gcgaacgcct acttggatgc gttggccgag
    44101 cagcgtcggg cgaggggatt ggtcgggacc gcggttgcgt ggggaccgtg ggccggtgac
    44161 ggcatggccg ccggcgaaac cggcgcacag ctgcaccgga tgggcctggc gtcgatggaa
    44221 ccgagcgcgg cgctgctggc acttcagggt gcattggacc gcgatgagac ctccctcgtc
    44281 gtggccgatg tcgattgggc acggttcgcc ccagccttca cctcggcacg tcgacgcccg
    44341 ctgctggaca ccatcgacga ggcccgagcc gcattggaaa ccaccggcga acaagcgggc
    44401 acaggcaaac ccgttgagct gacgcaacgc ctggccggac tgtcgcggaa ggaacgcgac
    44461 gatgcggtat tggatctggt gcgggcggag acggcggctg tgctgggacg cgacgatgcc
    44521 acggccctgg cgccatcgcg gccgttccag gaactcggat tcgactcctt gatggcggtg
    44581 gagctgcgca accggctgaa caccgccacc gggatccagc tgcccgccag cacgattttc
    44641 gactacccca atgccgagtc gctgtcgcgt cacctctgcg ccgagctttt cccaacggag
    44701 actaccgtgg actcggccct tgccgagctc gatcgaatcg agcagcagct ctcgatgctc
    44761 accggcgaag cgcgggcacg ggaccgaatc gcgacacgac tgcgagccct ccacgagaag
    44821 tggaacagcg cagctgaagt accgaccgga gccgatgtcc tgagcacgct cgattcggcg
    44881 acgcacgacg agatattcga gttcatcgac aacgagctcg acctgtcctg agcagttcct
    44941 gcggaacttc aagcgccgaa atcgggtgga aatcacaatg gccaatgaag aaaagctctt
    45001 cggctatctg aagaaggtaa ctgcggacct gcatcagacc cggcagcgcc tgctcgcggc
    45061 cgagagccgg agtcaggagc cgatcgcgat cgtctcggcg agctgccgac tgcccggcgg
    45121 cgtcgactct cccgaagcgc tctggcaact cgtgcgcact ggcaccgacg ccatctcgga
    45181 gttccccgcc gaccggggct gggatctcgg ccggttgtac gatcccgacc cgaaccacca
    45241 gggaacgtcg tacacgcggg ccggcggttt cctcgcagga gcgggcgatt tcgaccccgc
    45301 catgttcggg atttcgccgc gtgaggcgtt ggcgatggac ccgcagcaac ggttgttgct
    45361 ggagctgtcc tgggaggccc tcgaacgggc gggcatagac ccgacatccc tgcgcggcag
    45421 caagaccggt gtcttcggtg gtgtcacgcc ccaggagtac gggccgtcct tgcaggagat
    45481 gagccgaaac gctgggggtt ttggactcac cgggcggatg gtgagtgtgg cgtcgggtcg
    45541 ggttgcgtat tcgtttggtt ttgagggtcc tgcggtgacg gtggatacgg cgtgttcgtc
    45601 gtcgttggtg gccctgcatt tggcgtgtca gtcgttgcgt tccggcgaat gcgatctcgc
    45661 gctggccggc ggtgtgacgg tgatggcgac accggcgacg ttcgtggagt tctcccgtca
    45721 gcgtggtttg gctccggacg ggcggtgcaa gtcgttcgcg gctgccgcgg atggcaccgg
    45781 gtggggtgag ggtgccggtc tggtgttgct ggagcggttg tcggatgcgc ggcggaatgg
    45841 gcacgaggtt ctggcggtgg tgcggggtag cgcggtgaac caggacggcg cgtcgaatgg
    45901 tttgactgcg ccgaatggtc cgtcgcagca gcgggtgatc acccaggcgt tggcgagtgc
    45961 ggggctgtcg gtttccgatg tggatgcggt cgaggcacat gggaccggga ccacgttggg
    46021 tgatccgatc gaggcacagg ccctgatcgc cacgtacggg cagggccggg agaaggatcg
    46081 gccgttgtgg ttggggtcgg tcaagtccaa catcggtcac acgcaggcgg ccgctggcgt
    46141 tgccggcgtc atcaagatgg tcttggcgat gcggcacggg cagctgcccg ccacgttgca
    46201 tgtggatgag cccacgtcgg cggtggactg gtcggcgggt tcggtccggc ttctcacgga
    46261 gaacacgccc tggccggaca gtggtcgtcc ttgccgggtg ggggtgtcgt cgttcgggat
    46321 cagcggcacc aacgcacatg tgattctcga acagtctcca gtcgagcagg gcgaaccggc
    46381 cgggccggtc gaaggcgagc gggaaccgga tgtagccgtc cccgtggtgc cttgggtgct
    46441 gtcgggtaag acaccggagg ctgcgcgggc gcaggccgaa cgggtgcatt cgcatatcga
    46501 ggaccggccg gggctgtcgc cggtggatgt ggcgtattcg ctaggaatga cacgcgcggc
    46561 gctggatgaa cgcgcagtgg tgttgggctc ggaccgtgcc gcgctcctga ccgggttgag
    46621 ggcattcgcc gacggctgcg atgcgcccga agtggtttcg gggtctgtgg ggcttggtgg
    46681 ccgcgtcggg ttcgtgttct cgggtcaggg tggtcagtgg ccggggatgg gccgggggct
    46741 ctactcggtg tttccggtgt tcgccgacgc gttcgacgag gcttgcgcgg agttggatgc
    46801 acacctgggc caggaactgc gggttcggga tgtggtgttc ggttcgcaag cgtggttgct
    46861 ggatcggacg gtgtgggcgc agtcgggttt gttcgcgttg cagattggct tgctgcggct
    46921 gctgggttcg tggggtgttc ggccggatgt ggtgttgggg cactcggtgg gtgagctggc
    46981 tgcggtgcat gcggctggtg tgttgtcgtt gtcggaggcc gcgcggttgg tggcgggtcg
    47041 cgcccggttg atgcaggcgt tgccttctgg tggtgccatg ctcgcggtcg ctacgggtga
    47101 gtttcaggtc gatcctctgc tggatggggt gcgggaccgg atcggtatcg cggcggtgaa
    47161 tggcccggaa tcggttgtgc tctctggtga ccgcgagctg ctcaccgaga tcgctgatcg
    47221 gttgcacgat caggggtgcc ggacccggtg gttgcgggtg tcgcatgctt tccattcgcc
    47281 ccatatggag ccgatgctgg aggagttcgc ccagatctcc cgaggccgcg aatatcacgc
    47341 accggaactg ccgatcatct cgaccctgat cggtgagctg gacggtggtc gagtgatggg
    47401 cactcccgag tactgggtgc gtcaggtgcg tgagcccgtc cgtttcgccg agggtgtcca
    47461 ggcgcttgtc ggtcagggtg tcggcacgat tgtcgaattg ggtccggacg gggcgttgtc
    47521 gacgttggtc gaggagtgtg tggcggaatc cgggcgggtg gccgggatcc cgctgatgcg
    47581 caaggaccgc gacgaggcgc gaaccgtgct ggcagctttg gcgcagatcc acacccgtgg
    47641 tggtgaggtg gactggcggt cgtttttcgc cggtaccggg gcgaagcaag tcgacctgcc
    47701 cacctacgcc ttccagcggc agcggtactg gctggcatcc accgggcgtg cgggtgacgt
    47761 gaccgccgcc ggattggccg aggcggacca tccgctgctc ggtgcggtgg ttgcgttggc
    47821 agacggcgaa ggtgtggtgc tgaccggtcg gttgacagcg ggttcgcatc cgtggttgtc
    47881 cgatcaccgg gtgctgggcg aaatcgtcgt ccccggcacc gcgatcgtcg agctggtgtg
    47941 gcacgtcggc gagcgcctcg gttgtggccg ggtggaagaa ctggctttgg aagcgcccct
    48001 gatcctgccg gatcatggag cggtccaggt tcaggtgctg gtgggaccgc ccggggaatc
    48061 cggagcccgg tcggtggcgc tctactcctg tcctggcgag gcgatcgaac ccgagtggaa
    48121 gaagcacgcg acgggcgtgc ttctcccacc cgtggccgcc gagaaccatg agctgaccgc
    48181 atggcccccg gagaatgcga ccgaaatcga tgcagacggg gtctacgcat tccttgaagg
    48241 gcacggtttc gcgtacggac cggcctttag atgtctgcgc ggtgcctggc gacgaggcgg
    48301 ggaggtgttc gccgaagtcg cattgccgga tgacatgcag gcgggggtcg atcgattcgg
    48361 cgtccacccc gcgttgctgg acgcggttct gcatgccgcc gcagccgaga cgtcggtggt
    48421 ccagagcgaa gcgcgggtgc cgttctcgtg gcgtggggtg gaacttcgcg ccactgaaag
    48481 cgcggtggtg cgggcgcgcc tctcgttgac ttcggatgac gaactgtcgt tggtcgcagt
    48541 ggacccggct ggccgattcg tggccacggt tgattcgctg gtgacccgac cgatctcccg
    48601 gcagcaggtg aggtctggcg cgatcggtga ttgcctgttc gaggtggagt ggcaccggaa
    48661 ggcgttgttg ggaacaaccg ccggcgacga ccttgccatc gtcggtgacg gtcccagttg
    48721 gccggaatcg gtgcgcgcaa ccgcacggtt cgcgaccctg gatgagttcc gtgcggccgt
    48781 ggactcggac gttcctgccc cgggttcggt gttggtcgca gctatgtcgg ccgaagaggt
    48841 cgagggtgga tccctgccgt cgcgcgccca agagtcgacc tccgatctgc tggctctcgt
    48901 gcagtcgtgg cttgcggacg agcggttcgc cgaatcccag ctcgtggtcg tcacgcgtgc
    48961 agcggtgtcg gccgactcgg attcggacgt cgcggacctg gtgggtgcgt cgtcgtgggg
    49021 gttgttgagt tcagcccagt cggagaaccc gggtcgcttc gtgctggtgg acgtggacgg
    49081 cacacctgag tcgtggcagg cgttgccggc cgccgtgcga gcaggagaac cgcagctggc
    49141 acttcggcgc ggcgtggcgc tggtgcctcg gttggcgcga ctcacggtgc gcgaggaggg
    49201 ctcctccccg caactcgaca cggacgggac cgtcctcatc acgggtggca ccggtgcgtt
    49261 ggggggagtg gttgcccgtc acctggtgga ggagcacggg attcggcgtt tggtgttggc
    49321 aggccggcgt ggctggaatg cgcctggagt ccacgagttg gtggatgagc tggcgcgcgc
    49381 gggcgccgtg gttgaggtgg tggcttgcga tgtggctgac cgcaccgatc tggagcacgt
    49441 gctggccgcc attccggtcg actggccgct gcgggggatc gtgcataccg ctggggtgct
    49501 ggccgacgga gtgatcgggt ccttgtcggc ggcggatgtg ggcacggtgt ttgccccgaa
    49561 ggtgacgggg gcatggcatc tgcacgagtt gacccgcgat ctggatctgt cgttcttcgt
    49621 tcttttctct tccttctccg ggattgcggg tgccgcaggg caggccaact acgcggcggc
    49681 gaacacgttc ctggatgcat tggcgcgtta tcgccgggcg cgtgggctgc ctgggttgtc
    49741 gttggcgtgg ggactgtggg cgcaacccag cggtatgacg agtggcttgg acgcggcgtc
    49801 ggtggagcgg ttggcgcgga cgggcatcgc agaactttcc acggaggatg gactccgcct
    49861 gttcgatgcc gcgttcgcga aggaccgggc ttgcgtcgtt gccgctcgat tggacagggc
    49921 gctgctggtc gggaacggac gatcgcacgc gattccggcg ctgttgagcg cgttggttcc
    49981 tgttcgcggc ggtgtggcga ggaaaacagc caattctcag gccgcggatg aggacgcact
    50041 gttgggtttg gtgcgggagc acgtttcggc cgtgctgggt tattcgggtg cggtcgaggt
    50101 tgggggcgac cgtgctttcc gtgatctggg ttttgattcg ttgtctggcg tggagttgcg
    50161 gaaccgcctt gccggggtgc tgggggtgcg gttgccggcg actgcggtgt tcgactatcc
    50221 gacgccgcgg gcgctggcgc gtttcctgca tcaggaactg gcaggcgagg tcgcgtccac
    50281 gtcgacgccg gtgaccaggg cagcgagtgc cgaagaggat cttgttgcga ttgtcgggat
    50341 gggatgtcgt tttccgggtg gggtgtcgtc gccggaggag ctttggcggc tggtggccgg
    50401 cggcgtggat gcggtggctg ggttcccaga cgatcgcggc tgggatctcg cggcgttgta
    50461 cgatcctgat cccgatcgtc tcgggacctc gtatgtgtgt gagggcgggt ttctgcggga
    50521 cgcggcggag ttcgatgctg acatgttcgg catcagcccg cgtgaggcgt tggcgatgga
    50581 tccgcagcag cggttgctgc tggaggtcgc ctgggaaacc ttggagcggg ctgggatcga
    50641 tccgttctcg ttgcacggca gccggaccgg tgtgttcgcg ggcttgatgt accacgacta
    50701 tggggcccga ttcattacca gagcaccgga gggcttcgaa gggcacctcg ggacgggcaa
    50761 tgcggggagc gtgctgtcgg gtcgggttgc gtattcgttt ggtttcgagg gtcctgcggt
    50821 gacggtggat acggcgtgtt cgtcgtcgtt ggtggcgtta cacctggcgg gtcaagcact
    50881 gcgggccggt gagtgcgaat tcgcccttgc cggtggcgtc acggtgatgt cgacgccgac
    50941 gacgttcgtg gagttctccc gtcaacgggg tctggctccg gatgggcggt gcaagtcgtt
    51001 cgcggcggcc gcggatggca ccgggtgggg cgagggtgcc ggtctggtgt tgctggagcg
    51061 gttgtcggat gcccggcgca atgggcacga ggttctggcg gtggtgcggg gtagcgcggt
    51121 gaaccaggac ggcgcgtcga atggcttgac tgcgccaaat ggtccgtcac agcaaagggt
    51181 gatcacccag gcactcacga gtgccgggct gtccgtgtcc gacgtggatg ctgtggaggc
    51241 gcatgggacg ggcacgcggc ttggtgatcc gatcgaggcg caggcgttga tcgctacgta
    51301 cggccgggat cgtgatcccg gtcggccgtt gtggctgggg tcggtgaagt cgaatattgg
    51361 tcacacccag gcggcggcgg gtgtcgctgg tgtgatcaag atggtgatgg cgatgcggca
    51421 gggggagctg ccgcgcacgt tgcacgtgga cgagccctcc gcgcaggtgg actggtctgc
    51481 gggcacggtc caactcctca cggagaacac gccctggccc gacagcggtc gtcttcgccg
    51541 ggcgggcgtg tcatcgttcg ggatcagtgg caccaacgcg cacctgatcc ttgaacaacc
    51601 tccgcgagag tcgcagcgct caacagagcc ggattcgggt tctgtccgcg attttccggt
    51661 ggtgccgtgg atggtgtcgg gcaaaacacc cgaagcgcta tccgcccagg cagatgcatt
    51721 gatgtcctac ttgagcaatc gcgttgatgc ttccccgcga gatatcggtt attcgcttgc
    51781 ggtgacccgt ccggcgttgg accaccgcgc tgtcgtgctg ggtgcggatc gtgccgcgtt
    51841 gctgccgggc ttgaaagcgc tggccgttag taatgacgct gccgaggtga tcaccggcac
    51901 tcgtgccgct gggccggtcg gattcgtgtt ctccggtcaa ggtggtcagt ggcccgggat
    51961 gggaagcggg ctccactcgg cgtttccggt gttcgccgac gcgtttgacg aagcctgctg
    52021 cgagctggat gcgcatctcg ggcagatggc ccggctacga gatgtgttgt ccggttcgga
    52081 tacgcaactt ctggaccaga ccttgtgggc gcagccgggc ctgttcgcgt tgcaagtcgg
    52141 actctgggag ttgttgggtt cgtggggtgt ccggcccgct gtggtgctgg gccactcggt
    52201 cggtgagctg gcggcggcgt tcgcggctgg agtgttgtcg ttgcgggatg cggctcggct
    52261 ggtggcgggc cgtgcccggt tgatgcaagc cctgccaact ggcggtgcca tgctcgctgc
    52321 ggctgctgga gaggagcagc tgcgcccgtt gctggccgac tgcggtgatc gtgtggggat
    52381 cgccgcggtc aacgctcccg ggtcggtggt gctctccggt gatcgggatg tgctcgatga
    52441 cattgccggt cggctggacg ggcaagggat ccggtccagg tggttgcggg tttcgcatgc
    52501 gtttcattcg catcggatgg atccgatgct ggcggagttc accgaaatcg cccggagcgt
    52561 ggactaccgg tcgtcagggc tgccgatcgt gtcgacgttg acgggtgagc tcgatgaggt
    52621 cggcatgccg gctacgccgg agtattgggt gcgccaggtg cgagaacccg tccgcttcgc
    52681 cgacggtgtt gctgcgctcg cggctcacgg tgtgagcacc gtcgtcgagg tcggtccgga
    52741 tggggtgttg tcggcgctgg tgcaggagtg cgcggccgga tccgatcagg gcggacgggt
    52801 ggccgcggtt ccgctcatgc gcagcaatcg cgacgaggcg cacacggtga caacggcatt
    52861 ggcgcagatc catgtgcgtg gtgctgaggt ggactggcgg tcgtttttcg ccggtaccgg
    52921 ggcaaagcag gtcgagctgc ccacgtatgc cttccaacga cagcggtact ggcttgactc
    52981 accatccgaa ccggtcgggc aatccgccga tcccgcgcgc cagtcgggct tctgggaact
    53041 cgtcgagcag gaagatgtca gcgcgctcag cgccgctctg cacattaccg gcgatcacga
    53101 cgtgcaggcg tccctggaat cggtggttcc ggtcctctcc tcctggcatc gccggatccg
    53161 caacgaatcc ctggtgcacc agtggcggta ccggatttcc tggcatgagc gggcagattt
    53221 gccagacccc tcgttgtcgg ggacatggct cgtcgtcgtg ccggaggggt ggtcggcgag
    53281 tcggcaagtt ctgcgtttca acgagatgtt cgaggaacgg ggttgcccgg cagttctgtt
    53341 cgagctcgcc gggcacgacg aggaagccct ggcgcaacga ttccgctcgt tgcctgttgc
    53401 gtcaggggga ataagcggcg tgttgtcctt gctggcgctg gatgaatcgc cgtcctcgcc
    53461 gaacgctgct ttgccgaatg gcgcgctgaa ctcgttggta ctgctgcgag ctctgcgggc
    53521 cgcggatgtg tcggcgccat tgtggttggc gacgtgtggt ggtgtcgcgg tcggggatgt
    53581 gccggtgaac ccggggcagg cgctggtgtg gggactgggt cgcgtcgtcg gtctggagca
    53641 tccggcctgg tggggtggcc tggtcgacgt gccgtgcttg ctcgatgagg acgctcgaga
    53701 acgcttgtcg gtcgtgttgg caggtcttgg cgaggacgag atcgcggtac gtcccggtgg
    53761 tgtgttcgtg cggcggttgg aacgcgctgg tgcggcgtcg ggtgccgggt cggtgtggcg
    53821 tcctcggggg acggtgttgg tgacgggtgg tacgggcggt ttgggggcgc atgttgcccg
    53881 gtggttggcg ggtgccgggg ctgagcatgt ggtgttgacc agccgtcgag gcgcggcggc
    53941 tccgggcgct ggagatttgc gggcggagct ggaggcgctg ggcgctcggg tttcgatcac
    54001 ggcctgcgac gtggccgatc gtgacgcttt ggccgaagtg ttggcgacca ttccggatga
    54061 ttgcccgctg accgcggtga tgcatgcggc gggggtcgtt gaagtcggcg acgtggcgtc
    54121 gatgtgtttg accgacttcg ttggggtgct gtcggcgaag gcaggtggtg cggcgaatct
    54181 cgatgagttg ctcgccgatg tcgagctgga tgccttcgtg ctgttctcat ccgtctcggg
    54241 tgtgtggggt gctggcgggc agggcgctta tgcggcggcg aatgcctact tggatgcgtt
    54301 ggcgcagcag cgtcgggcaa gggggttggt ggggactgcg gttgcgtggg gcccgtgggc
    54361 cggtgacgga atggccgcag gtgaaggcgg tgcacagctg cgccgggccg gcctggtgcc
    54421 aatggctgcg gatcgggcgt tgctggcact tcagggcgca ttggatcgtg acgagacatc
    54481 cctggtcgtg gccgatatgg cgtgggagag gttcgccccg gtgttcgcca tgtcccgtcg
    54541 gcgtccgctg ctcgacgagc tgcccgaagc acagcaggcg ttggcggatg cggagaacac
    54601 cactgatgct gcggactcgg ccgtcccgct accgcggctc gcgggcatgg cagccgccga
    54661 acgccgccgc gcgatgctgg acctggtgct ggcggaggcc tcgattgtgt tgggacacaa
    54721 cgggtctgac ccagttggtc ccgaccgggc gttccaggag ctcggatttg attcgctgat
    54781 ggccgtcgaa ctgcgcaaca ggttgggcga ggcaacagga ttgagtctgc cggccacgtt
    54841 gatcttcgat tatccgagcc catccgcgct ggctgagcag ctggtcggcg agctggtggg
    54901 agcgcagccc gcgaccaccg tcgtggccgg ggccgatcca gtggatgatc cggttgtcgt
    54961 ggtcgcgatg ggatgccggt atccgggcga cgtctgctcg cccgaggagc tgtggcagct
    55021 ggtttctgcg ggacgtgatg cggtatcgac gttccccgtc gatcggggtt gggactgcaa
    55081 cacgttgttc gacccggatc cggatcgggc aggcagtacc tatgtgcgag aaggtgcctt
    55141 cctgaccggt gctgatcggt tcgacgccgg gttcttcggc atcagccctc gcgaggcgcg
    55201 cgcaatggat ccgcagcaga ggttgttgct cgaagtggcg tgggaggttt tcgaacgagc
    55261 aggaatcgct ccgctgtcgt tgcggggtag caggaccggt gtgttcgcgg ggaccaatgg
    55321 gcaggaccac ggtgcgaaag tggctgccgc gccggaggcg gcgggtcacc tcctgaccgg
    55381 aaacgccgcg agtgtcctgg ccggccggct ttcctacacg ttcggccttg aggggcctgc
    55441 ggtggcggtg gataccgcgt gttcgtcgtc gttggtggcg ttgcatttgg cgtgccagtc
    55501 gctgcgttcg ggtgagtgtg atatggcgtt ggcaggtggt gtgacggtga tgtcgacacc
    55561 cctggctttc ctcgagttct ctcgtcagcg cggtttggcg ccagatggtc ggtgcaagtc
    55621 gtttgcggcc gctgcggatg gcaccgggtg gggtgagggt gccggcctgg tgttgctgga
    55681 gcggttgtcg gatgctcgtc ggaatggtca ccgggtgttg gccgtggttc gcgggtctgc
    55741 ggtgaatcag gatggtgcgt cgaatggcct gactgcgccg aatggtccgt cgcagcagcg
    55801 ggtgattcgg caggccctcg cgaatgcggg gctgtcggcg tccgatgtgg atgtcgtgga
    55861 ggcgcacggg accggtaccg ggctcgggga tccgatcgag gcgcaggcgc tgatcgcgac
    55921 atatgggcag gagcgggatc ctgagcgggc cctgtggctg gggtcgatca agtccaacat
    55981 cggccacacg caggcggcgg ccggtgtggc gggggtcatc aagatggtgc aggccatgcg
    56041 gcacggggag ttgcctgcga cgttgcacgt ggacaagccc actccacagg tggactggtc
    56101 tgccggggcc gttcggctcc tcaccgggaa cacgccctgg cccgagagcg gccgtcctcg
    56161 tcgagcgggg gtgtcgtcgt tcgggatcag cggcaccaac gcacacctca tcctcgaaca
    56221 accaccgtcg gaaccagcgg agatcgacca atcggatcgg cgggtcactg cgcatccagc
    56281 ggtgatcccg tggatgttgt cggctaggag tctcgcagcg ctgcaggccc aagcggctgc
    56341 gctgcaggcc cggctggacc ggggtcctgg cgcttctccg ctggatttgg ggtattcact
    56401 cgcgaccact cgttctgtgc tggacgaacg cgccgtcgtg tggggtgccg atcgggaggc
    56461 actgctgtcc aggctggcag cgctcgccga tggccggacg gcgccggggg tgataacggg
    56521 ctctgcgaat tccggtggcc gcatcggatt cgttttttcc ggtcagggca gtcagtggct
    56581 ggggatggga aaggcgttgt gcgcggcttt cccggcgttc gcggacgcct tcgaggaagc
    56641 ctgcgacgcg ctaagcgcac acctgggcgc ggacgttcgg ggtgtgctgt tcggtgctga
    56701 tgagcagatg ctcgaccgga cgctgtgggc gcagtcgggg atcttcgcgg ttcaagtcgg
    56761 cctcctggga ttgctgaggt cgtggggcgt gcggccggcc gcggtgctgg ggcactcggt
    56821 cggcgagttg gctgcggcgc acgcggctgg tgtgttgtcc ttgccggacg ctgcacggtt
    56881 ggttgcggct cgggcccacc tgatgcaggc attgcccacc ggcggcgcaa tgctcgcggt
    56941 cgccaccagc gaggcggcgg tcggaccgct gctttccggg gtgtgcgatc gggtcagcat
    57001 cgctgcgatc aacggccccg agtcggtagt gctctccggc gaccgcgatg tgctcgtgga
    57061 gctcgcaggc gaattcgatg cccgagggct taggaccaaa tggttgcggg tctcccatgc
    57121 tttccactcg caccggatgg aaccgattct ggacgagtac gcggaaaccg ccaggtgcgt
    57181 cgagttcggt gaaccggtgg tgccgatcgt ctccgccgcg accggtgcgc tggacaccac
    57241 cggactgatg tgcgcggccg actactggac gcgccaagtg cgtgatcctg tccgcttcgg
    57301 agacggtgtc cgggcgctcg tcggccaagg cgtggacacg atcgtcgagt tcggcccgga
    57361 cggggcgttg tcggccctgg tcgagcagtg cttggccggg tccgaccagg ctgggagggt
    57421 ggcggcgatc ccgctgatgc gcagggaccg cgatgaggtc gagaccgcgg tggcggccct
    57481 ggcgcacgtg cacgtccgcg gtggtgcggt ggactggtcg gcttgcttcg ccggcaccgg
    57541 cgcccgcacc gtcgagttgc ccacctacgc cttccaacgc cagcggtact ggctggccgg
    57601 gcaagcggac gggcgcggcg gcgatgtggt tgccgacccg gtcgacgcgc gcttctggga
    57661 gttggtcgag cgcgccgatc cggaaccgtt ggtggatgaa ctctgcatcg accgggacca
    57721 gcccttccgg gaggtgctgc ccgttctggc ttcctggcgc gagaaacaac gccaggaggc
    57781 cctcgcggat tcctggcgct accaggtgcg ctggaggtcc gtcgaggtgc cgtccgcagc
    57841 cgccctccgg ggcgtgtggc tggtggtgct tccagctgac gtgccccgag atcaaccggc
    57901 ggtcgtcatc gacgcgctga tcgcgcgcgg cgccgaggtc gcggtcctgg aattgaccga
    57961 gcaggacctc caacgcagtg cgcttgtgga caaggtgcgc gccgtcattg cggaccgcac
    58021 cgaggtgacg ggtgtgttgt ctctgttggc gatggacggc atgccctgcg cggcgcatcc
    58081 gcacctgtcc cgtggtgtcg ccgctaccgt gatcctgacg caggtgttgg gcgatgcggg
    58141 tgtttccgcc ccgctgtggc tggccacgac cggtggcgtc gaggccggga ccgaggacgg
    58201 tccggccgat ccggaccacg gcttgatctg ggggctcggc agggtcgtcg gccttgaaca
    58261 tccgcagtgg tggggtggcc tgatcgacct tccggagaca ctggacgaga cgtcccggaa
    58321 cgggttggtg gccgcactcg ccgggacggc ggccgaagat cagctcgccg tgcgttcatc
    58381 cgggttgttc gttcgcagag tggtgcgcgc agcgcggaac ccccggtcag agacatggcg
    58441 tagccgggga acggtcctca tcacgggcgg aacaggcgcg ctcggtgccg aggtcgcacg
    58501 atggctggcc cggcggggag ctgagcacct ggtgttgatc agtcgccgcg gcccggaagc
    58561 tcccggcgca gcggacctag gggccgagct gactgaactc ggcgtgaaag tcacagtctt
    58621 ggcctgcgat gtgacggacc gcgacgagct ggcggcggtg ctggcggccg ttcccacgga
    58681 gtatccgctg tcggcggtcg tgcacaccgc cggcgtcggg acgcctgcga acctggccga
    58741 gacgaccttg gcgcagttcg ccgacgtgtt gtcggccaag gtcgtcggcg cggcgaacct
    58801 ggaccggctg cttggcgggc aaccgttgga cgccttcgtg ctgttctcct cgatctcggg
    58861 agtttgggga gccggcggcc aaggagccta ttcggccgcc aatgcgtatc tcgatgccct
    58921 tgccgagcgc cgacgggctt gcgggcggcc ggcgacgtgc atcgcctggg gtccgtgggc
    58981 gggtgcgggc atggccgttc aggaaggtaa cgaggcgcat ctccgccgaa ggggcctggt
    59041 accgatggaa ccgcagtcgg ccctcttcgc gctgcaacag gccctgtccc aacgagaaac
    59101 cgccatcacc gtcgcagatg tggactggga gcgattcgcc gcctctttca ccgcggcccg
    59161 cccgcgacca ctgttggaag agatcgtgga tctacggccc gacaccgaga ccgaggagaa
    59221 gcacggtgcc ggcgagctgg ggcagcagct ggccgcactg ccgcccgctg agcgcggaca
    59281 cctgctgctg gaggtggtgc tggcggaaac cgccagcacc ctggggcacg attcggcgga
    59341 ggctgtgcaa cccgatcgga ccttcgccga actgggcttc gattcgctga ccgcggtaga
    59401 gctgcgcaac aggttgaacg cggtgaccgg gcttcgcctg ccgccgacgc tggttttcga
    59461 ccacccgacg ccgctggcgt tgtccgaaca gttggttccg gccctggtcg cggagccgga
    59521 caacggcatc gaatcgctgc tcgccgagct cgacaggctg gataccacgt tggcgcaagg
    59581 gccttcgatc ccactggaag accaggccaa ggtggcggag cgcttgcacg cactcctcgc
    59641 caagtgggac ggggcgcgtg acggcacggc cagagcgacg tcaccccaat cgctgacggc
    59701 ggccacggac gacgaaatct tcgacctcat cgaccggaag ttccggcgct gaccgccctt
    59761 tcctcgcctc agctcccctg attactggaa cggtgtattt cgatggccaa tgaagaaaag
    59821 ctccgcgagt acctcaagcg tgtcgtcgtc gaactggaag aggcgcacga acgcctgcac
    59881 gagttggagc gccaggagca cgaccccatc gcgatcgtgt cgatgggatg tcgttatccc
    59941 ggtggcgtct ccactccgga ggagctgtgg cgactggtcg tcgacggagg agacgcgatc
    60001 gcgaacttcc ccgaagaccg tggctggaat ctggacgagc tgttcgatcc tgatccgggc
    60061 cgagccggga cctcctacgt ccgcgagggt ggtttcctgc gcggggtcgc ggacttcgat
    60121 gccgggctct tcgggatcag tccgcgcgag gcacaggcga tggacccgca acagcggttg
    60181 ctgctggaga tctcgtggga ggtgttcgag cgcgccggca ttgacccgtt ttctttgcgg
    60241 ggtaccaaga ccggtgtgtt cgcgggcctg atctaccacg actacgcgtc gcggtttcgc
    60301 aagacccccg cggagttcga gggttacttc gccaccggca acgcgggcag cgtcgcatcc
    60361 ggccgggtgg cttacacctt cgggttagag ggcccggcgg tcaccgtgga caccgcctgc
    60421 tcgtcgtccc tggtggcgct gcacctggcc tgccagtccc tgcggctggg cgaatgcgac
    60481 ctggccctgg ccggtggcat ttcggtgatg gccacgccgg gagccttcgt cgagttcagc
    60541 cggcaacgcg cactcgcctc ggatggccgg tgcaagccct tcgcggatgc cgccgacggc
    60601 accggctggg gcgagggcgc cggaatgctg ctgctggaac ggctgtcgga cgcacgacga
    60661 aacggccacc cggtgctggc ggcggtggtc ggttccgcga tcaaccagga cgggacgtcc
    60721 aacggcctga ccgcgcccag cggtcccgca cagcagcgag tgatccgcca agccctggcg
    60781 aacgccgggt tgtcgcccgc cgaggtcgat gtggtcgagg cgcacggcac gggcacggcc
    60841 ttgggcgacc cgatcgaggc gcaggccctg atcgccacct acggggcgaa ccggtcggcg
    60901 gatcatccgc tgctgctggg ttccctcaag tcgaacatcg gccacaccca ggctgccgcc
    60961 ggtgtggccg gggtgatcaa gtcggtcctg gccatcaggc accgggagat gccccgcagc
    61021 ctgcacatcg accagccatc gcagcacgtg gactggtcgg cgggcgcggt gcggctgctc
    61081 acggacagcg ttgactggcc ggatctcggc aggccgcgcc gagcaggggt gtcctcgttc
    61141 ggcatgagcg gtaccaacgc acacctgatc gtcgaggaag tatccgacga gccggtctcg
    61201 ggcagtaccg agccgaccgg ggcatttccc tggccgctgt ccggcaagac ggagacggca
    61261 ttgcgcgagc aggctgccga gttgctctcc gtagtgaccg agcacccgga gccgggactg
    61321 ggggacgtcg ggtactcgct ggccaccggt cgcgctgcga tggagcaccg ggctgtcgtg
    61381 gttgccgacg atcgggactc tttcgtcgcc ggactgacgg cgttggctgc gggcgttccg
    61441 gcagccaacg tggtgcaggg cgcggccgac tgcaagggaa aggtcgcgtt cgtgttcccc
    61501 ggccagggct cgcattggca ggggatggcg agggaactgt ccgaatcctc gccggtgttc
    61561 cggcggaagc tggcggaatg cgcggcggct acggcccctt acgtggactg gtcgctgctc
    61621 ggcgtccttc gcggtgatcc cgatgcaccc gcgctggatc gcgacgacgt gattcagctc
    61681 gcgctgttcg ccatgatggt gtcgctggcc gaactgtggc gttcgtgcgg agtggagccc
    61741 gccgcggtgg tcggtcattc ccagggcgag atcgccgccg cccatgtggc aggcgctttg
    61801 tccttgactg atgcggtgcg catcatcgct gcccgctgcg atgcggtgtc ggcgctgacc
    61861 gggaagggag gcatgctcgc gattgccttg ccggaaagcg cggtggtgaa gcgaatcgca
    61921 ggcctgccgg agctgaccgt tgcggcggtc aacggacccg gctccactgt cgtttccggc
    61981 gaaccgtcgg ctctggagcg tctgcagacc gaactgaccg cggaaaacgt gcagacccgg
    62041 cgggtgggaa ttgattacgc ctcgcattcg ccgcagatcg cgcaggtcca gggccggctt
    62101 ctggaccggc tgggcgaagt cgggtccgaa cctgctgaga tcgctttcta ctcgacggtc
    62161 accggcgagc ggacggacac cggccgactc gacgccgact actggtacca gaaccttcgg
    62221 cagcccgtcc gcttccagca gaccgtcgcc cggatggcag atcagggcta tcggttcttc
    62281 gtcgaggtga gcccgcaccc gctgctcacc gccggaatcc aggaaacgct ggaagccgcg
    62341 gacgcgggcg gggtggtggt cggttcgctg cggcgtggcg agggcggctc ccggcgctgg
    62401 ctgacttcgc tggccgagtg ccaggtgcgc ggactgccgg tgaattggga acaggtattc
    62461 ctcaacaccg gagcccgacg cgtgccgctg ccgacctacc cgttccagcg gcagcggtac
    62521 tggttggagt ccgccgagta cgacgcgggc gatctcggtt cggtgggctt gctctccgcc
    62581 gagcatcccc tgctcggggc tgcggtgacg ctggccgatg cgggcgggtt cctgctgacc
    62641 ggcaagctgt cggtcaagac ccagccctgg ttggccgacc acgtggtcgg cggggcgatc
    62701 ctgctgcccg gcaccgcgtt cgtggaaatg ctgatacgcg ccgcggacca ggtcgggtgc
    62761 gatctgatcg aggagttgtc cctgacgact ccgctggttt tgcccgcgac cggtgcggtg
    62821 caggtgcaga tcgcggttgg cggtccggac gaggccgggc gccgctcggt ccgcgtgcat
    62881 tcctgtcgag acgacgccgt gccgcaggac tcgtggacct gccacgcgac cggcacgttg
    62941 acctccagcg atcaccagga cgccggccag ggccccgatg ggatttggcc gcccaacgat
    63001 gctgtcgcgg ttccgctgga cagcttctac gcccgcgcag ctgagcgggg cttcgatttc
    63061 ggcccggcgt tccaggggtt gcaggcggct tggaagcgcg gagacgagat cttcgccgag
    63121 gtcggcctgc ccaccgcaca ccgcgaagac gccggcaggt tcggaatcca ccctgctctg
    63181 ctggatgcgg cactgcaggc gctgggcgca gccgaagagg atccggacga gggatggctc
    63241 ccgttcgcgt ggcaaggtgt gtccctcaaa gcgacgggcg cactttccct tcgggtgcac
    63301 ctcgttccgg cgggcgcgaa tgcggtgtcg gtgttcacga ccgacacgac tggccaagcc
    63361 gtgctctcca tcgattcgct ggtgctgcgc cagatttcgg acaagcagtt ggcagcggcc
    63421 cgtgcgatgg aacacgagtc cctgttccgg gtcgactgga agcgaatctc gcccggcgct
    63481 gccaagccgg tctcctgggc agtgatcggc aatgacgaac tcgcccgagc ctgcggctcg
    63541 gcacttggca cggaactcca ccccgacctg accgggttgg ctgacccgcc cccggacgtc
    63601 gtggtggtgc catgcggtgc gtctcgccag gacttggacg ttgcttccga ggcacgtgcc
    63661 gcgacacaac gcatgcttga cctgatccag gattggttgg cggcggcgcg attcgccgga
    63721 tctcgcctgg tggttgtgac gtgtggtgcg gcgtcgacag gtcccgccga gggtgtttcc
    63781 gacctggtgc atgctgcgtc gtggggtttg ttgcgttcgg cgcagtcgga gaacccggac
    63841 cgattcgtgt tggtcgatgt ggacggaacc gccgaatcat ggcgtgcgct cgcggcggcc
    63901 gtgcgttccg gagaaccgca gctggcgttg cgcgccggtg aagtccgggt gcctcgcctg
    63961 gcgcgatgtg ttgccgccga ggacagccgg atcccagtgc ccggtgcgga tgggacggtg
    64021 ttgatttccg gcggtacggg cctgctgggc gggttggttg cccggcattt ggtggcggag
    64081 cgcggtgtcc gccgcctggt gctcgcgggg cgacgcggct ggagcgcccc cggggtcacc
    64141 gacctggtgg atgagttggt gggcctggga gctgcggtcg aggtggcgag ctgcgatgtc
    64201 ggggatcggg cccagttgga ccggctgctg acgacgatct cggcagagtt cccgctgcgc
    64261 ggagtggtgc atgcggccgg ggcacttgcc gacggggtcg tcgagtcgct gacaccagag
    64321 cacgtggcaa aggtgttcgg cccgaaggcc gccggtgcgt ggcacctgca cgagttgact
    64381 cttgatctgg atctctcgtt cttcgtgctc ttctcctcgt tctccggcgt ggcgggggct
    64441 gcgggtcagg gaaactacgc ggcggcgaac gcgttcctgg acggcctggc tcagcaccgg
    64501 cggacggcgg ggctgcctgc ggtgtcgctg gcttggggct tgtgggagca gcccagcggg
    64561 atgaccggag cgctcgatgc ggcgggccgt agccgcattg cgcgcaccaa tccgccgatg
    64621 tccgcgccgg acgggttgcg gctgttcgag atggcgtttc gcgttccggg cgaatcgctt
    64681 ctggttccgg tccacgtcga cctgaacgcc ctgcgcgctg atgcggccga cggcggtgtg
    64741 cctgcgttgt tgcgcgacct ggtgccagcg cccgtgcggc ggagcgcggt caacgagtcg
    64801 gcggacgtca acggtctggt tggtcggctg cggaggctgc cggacctgga tcaggaaacc
    64861 cagctgttgg gtttggtgcg cgagcatgtt tcggcggtgc tggggcattc gggtgcggtc
    64921 gaggtcgggg ccgatcgtgc tttccgggat ttgggttttg attcgttgtc cggtgtggag
    64981 tttcggaacc ggcttggcgg ggtgctgggc gttcggttgc cggctactgc ggtgttcgac
    65041 tatccgacac cgcgggcgtt ggttcggttc ttgctcgaca aactgattgg tggcgtggag
    65101 gctccgactc ccgcaccggc ggctgtggcg gcggtgactg ctgacgatcc cgttgtgatc
    65161 gtggggatgg gctgtcgtta tccgggtggg gtgtcctcgc cggaggagct ttggcgtttg
    65221 gtggccgggg gcttggatgc ggtggcggag ttcccggacg atcgtggctg ggatcaggcg
    65281 gggttgttcg atccggatcc cgatcgtctt gggacctcgt atgtgtgtga gggtggcttc
    65341 ctgcgagatg cggcagagtt cgatgccggt ttcttcggga tttccccgcg tgaggcgttg
    65401 gcgatggatc cgcagcagcg gttgctgctg gaagtcgctt gggaaaccgt ggagcgggcg
    65461 gggattgatc cgctttcgtt gcgggggagc cggaccggcg tgttcgcggg gctgatgcac
    65521 cacgactacg gcgcgcggtt catcacgagg gcgccggagg gtttcgaggg ttatctaggt
    65581 aatggcagcg cgggaggcgt gttttcgggt cgggttgcgt attcgtttgg tttcgagggt
    65641 cctgcggtga cggtggatac ggcgtgttcg tcgtcgttgg tggcgctgca cctggcgggt
    65701 caagcactgc ggtctggtga gtgtgatctg gctcttgcgg gtggtgtgac ggtgatggcc
    65761 acgccgggga tgttcgtgga gttttcgcgt caacggggct tggcggcgga tgggcggtgc
    65821 aagtcgtttg cggcggctgc ggatggcacc ggttggggag aaggcgcggg cttggtgttg
    65881 ttggagcggc tgtcggatgc ccggcgcaac gggcacgcgg ttctggcggt cgtgcggggt
    65941 agcgcggtga atcaggatgg tgcgtcgaat ggtttgacgg cgccgaatgg gccctcgcag
    66001 cagcgggtga tcacgcaggc gttggcgagt gctggtttgt cggtgtctga tgtggacgcc
    66061 gtggaggcgc atgggactgg aaccaggctt ggtgatccga ttgaggcgca ggctctgatt
    66121 gccacttacg ggcaggggcg ggatagcgat cggccgttgt ggttggggtc ggtgaagtcg
    66181 aatattggtc atacgcaggc ggcggcgggt gtcgctggtg tgatcaagat ggtgatggcg
    66241 atgcggcacg ggcagctgcc cgcgacgttg catgtggatg aacctacgtc ggaagtggat
    66301 tggtcggcgg gggatgtcca gctcctcacg gagaacaccc cctggcccgg caacagccat
    66361 cctcggcggg tgggcgtgtc gtcgttcggg atcagcggca ccaacgcaca cgtcatcctc
    66421 gaacaagcct cgaaaacacc agacgagact gcggacaaga gcggtcccga ttcggaatcg
    66481 accgtggacc ttccagcggt cccgttgatc gtgtcgggga gaacaccggc agcgctcagc
    66541 gctcaggcga gcgcattgtt gtcctatttg ggtgagcgtg gcgatatttc cacgctggat
    66601 gcggcgtttt cgttggcttc ctcccgggcc gcgttggagg agcgggcggt ggtgctggga
    66661 gcggaccgcg aaacgttgtt gtccgggttg gaagcgctgg cttccggtcg cgaggcttct
    66721 ggggtggtgt cgggatcccc ggtctctggc ggggttgggt tcgtgttcgc cggtcagggc
    66781 ggacagtggt tggggatggg ccgggggctc tactcggttt ttccggtgtt cgctgacgcg
    66841 tttgacgaag catgtgccgg actggacgcg catctggggc aggacgtggg ggtccgggat
    66901 gtggtgtttg gttccgacgg gtccttgttg gatcggacgc tgtgggccca gtcgggtttg
    66961 ttcgcgttgc aggttggttt gctgagcctg ctgggttcgt ggggtgtccg gccgggtgtg
    67021 gtgctgggcc attcggtcgg cgagttcgcg gcggcggttg cggcgggagt gttgtcgttg
    67081 ccggatgcgg ctcggatggt ggcgggtcgt gcccggttga tgcaggcgtt gccttctggc
    67141 ggtgccatgt tggcggtggc tgctggtgag gagcagctgc ggccgttgtt ggccgatcgg
    67201 gttgatggtg cgggtatcgc cgcggtcaac gctcctgagt cggtggtgct ctccggcgat
    67261 cgggaggtgc ttgacgacat cgccggcgcg ctggatgggc aagggattcg gtggcggcgg
    67321 ttgcgggttt cgcatgcgtt tcattcgtat cggatggacc cgatgttgca ggagttcgcc
    67381 gaaatcgcac gcagcgtgga ctaccggcgt ggcgacctac cggtcgtgtc gacgttgacg
    67441 ggtgagctcg acaccgcagg tgtgatggct acgccggagt attgggtgcg tcaggttcga
    67501 gagcccgtcc gcttcgccga cggcgtccgg gtgctcgcgc agcaaggggt cgccacgatc
    67561 ttcgaactcg gccctgatgc gacgctgtcg gccctgattc ccgattgtca ttcgtgggct
    67621 gatcaggcca tgccgattcc gatgctgcgt aaagaccgta cggaaaccga aactgtggtc
    67681 gccgcggtgg cgcgggcgca cacgcgtggt gttccggtcg aatggtcggc gtatttcgcc
    67741 ggcaccgggg cacggcgggt cgagttgccg acgtatgcct tccagcggca gcggtactgg
    67801 ctggaaacat cggattacgg cgatgtgacg ggtatcggcc tggctgcggc ggagcatccg
    67861 ttgctggggg ccgtggttgc gctggccgat ggtgatggga tggtgctgac cggccggttg
    67921 tcggtgggga cgcatccgtg gctggcccag catcgcgtgc tgggcgaggt cgtcgtcccc
    67981 ggcaccgcca tcctggagat ggccctgcac gcaggggcgc gtctcggctg tgaccgggtg
    68041 gaagagctca ccctggaaac accgctggtg gtccccgaac gcgcggcggg tgccggtagt
    68101 cgtggccctg cgggagggac cacagtttca attgaaactg cggaagaacg tgtgcggacg
    68161 aacgacgcca tcgaaatcca gctgctggtg aacgcacccg acgaaggcgg tcggcgaagg
    68221 gtgtcgctgt attcccgccc ggccggtggg tcgagaggtg ggggttggac gcgccacgcc
    68281 accggcgaac tcgtcgtcgg caccaccggt ggtagggcgg ttcctgattg gtcggctgag
    68341 ggtgccgagt cgattgctct cgatgagttc tacgtcgctc tggccggaaa cgggttcgag
    68401 tacgggccgt tgttccaggg gcttcaggcg gcatggcgtc gtggtgacga ggttctcgcc
    68461 gaaatcgccc cgccggccga ggccgatgcg atggcgtcgg gatacctgct cgacccagcg
    68521 ttgctggatg ccgcgctgca ggcgtccgcg ctcggcgacc gcccggagca aggcggcgcg
    68581 tggctgccgt tctcattcac cggcgtcgaa ctttccgctc cggcagggac gatcagcagg
    68641 gtgcggctgg agaccaggcg acccgacgcg atatcggtgg ccgtgatgga tgagagtggg
    68701 cggttgctcg cctcgatcga ttctctcagg ctacgaagcg tgtcgtcggg acagctggcg
    68761 aatcgggacg ctgtccgcga cgcgctgttc gaggtgacct gggagccggt ggcgacgcag
    68821 tcgacggaac cgggtcgctg ggccctgctt ggtgatactg cctgcggtaa agacgatctc
    68881 atcaaactcg caacggattc cgccgaccgc tgcgcggatc tggcggcgct agccgagaaa
    68941 cttgattcca gcgcgctggt tcctgatgtc gtggtctact gcgccggaga acaggcggat
    69001 cccggcaccg gcgcagccgc acttgcggag acccagcaga cgttggctct gctccaagcg
    69061 tggttggctg agccgcggtt ggccgaggca cgtctggtgg tggtgacgtg tgcagcggtg
    69121 acgacggctc cgagtgacgg tgcatcagag ctggcacatg cgccgttgtg ggggttgttg
    69181 cgtgccgcgc aggtggagaa cccggggcag tttgtgctgg cggacgtcga cggaaccgcc
    69241 gaatcgtggc gtgcgttgcc gagtgcgttg ggctcgatgg aaccgcagtt ggccctgcgg
    69301 aagggcgcgg tgcgagcgcc ccgcttggct tcggtcgccg ggcagatcga cgtgcccgcg
    69361 gttgtggcgg atcccgaccg aaccgtgctg atttcgggcg gcacgggcct gttggggggc
    69421 gcggttgccc gccacctggt gaccgaacgc ggtgtccgcc gattggtgtt gacgggccgt
    69481 cgtggctggg atgctcctgg aatcaccgag ttggtgggtg agctgaacgg cctcggtgcc
    69541 gtggtcgacg tggtggcgtg cgacgtcgcg gatcgtgctg atctggagtc gttgctggcg
    69601 gcggtcccgg cggaatttcc gttgtgcggc gtggtgcatg ccgcgggggc gctggccgac
    69661 ggggtgatcg agtcgttgtc accggacgac gtgggagcgg tgttcggccc gaaggcggcg
    69721 ggggcgtgga atctgcacga gctgactcgt gatacggacc tgtcgttctt cgcgttgttc
    69781 tcctcgcttt ccggtgttgc cggcgctcct ggtcagggca attatgcggc ggcgaacgcg
    69841 ttcctggacg cattggcgca ttaccggcgg tcacagggac tgcctgcggt gtcgctggcc
    69901 tggggcctgt gggagcagcc gagcgggatg acggagacgc tcagcgaggt cgaccggagc
    69961 aggatcgcgc gcgccaaccc gccgttgtcc accaaggagg gattgcggct gttcgatgcc
    70021 gggctggcgc tggaccgggc agcggtagtt ccggcgaagt tggacaggac tttcctggcc
    70081 gagcaggcgc ggtcgggctc gctgcccgca ttgttgacgg cactggtacc ccccatccgt
    70141 cgtaataggc gggctagcgg aaccgagctc gcggacgagg gcaccctgct cggggtggtg
    70201 cgggagcatg ccgcggccgt gctggggtat tcgagcgcgg ctgacgtcgg ggtcgagcgc
    70261 gctttccggg atctgggttt tgattcgttg tctggtgtgg agttgcggaa ccgccttgcc
    70321 ggggtgctgg gggtgcggtt gccggcgact gcggtgttcg actatccgac gccgagggcg
    70381 ctggcccggt tcctgcacca ggaactggca gacgagatcg ctacgacgcc agcgccggtg
    70441 acgacgacca gggcaccggt cgccgaagac gatctcgtcg cgatagtcgg gatgggatgc
    70501 cgttttcccg gtcaggtgtc ctcgccggag gagctctggc gtttggtggc cgggggcgtg
    70561 gatgcggtcg cggacttccc agccgatcgc ggctgggatc tggcaggctt gttcgatccg
    70621 gacccggaac gggctgggaa gacctacgtg cgggaagggg ccttcctcac cgacgccgat
    70681 cggttcgatg cgggtttctt cgggatttcc ccgcgtgagg cgttggcgat ggatccgcag
    70741 caacggctgt tgctggagct gtcctgggag gccattgaac gggcagggat cgatccgggt
    70801 tcgctgaggg ggagtcggac cggtgtgttc gcggggctga tgtaccacga ctatggcgcc
    70861 cggttcgcca gccgagcccc ggaaggtttc gaggggtatc tcggcaatgg cagtgctggg
    70921 agtgtcgcgt cgggccggat tgcgtactcg tttggtttcg agggtcctgc ggtgacggtg
    70981 gatactgcgt gttcgtcgtc gttggtggcg ttgcatttgg cgggtcagtc gttgcgttcc
    71041 ggcgaatgcg atctcgccct tgccggtggt gtgacggtga tgtcgacgcc cgggacgttt
    71101 gtggaattct cccgtcagcg gggcctggca ccggacgggc ggtgcaagtc gttcgcggag
    71161 agcgcggacg gtaccggttg gggtgagggt gctggtttgg tgttgttgga gcggttgtcg
    71221 gatgctcggc ggaatgggca tcgggtgttg gcggtggttc gtgggtcggc ggtgaatcag
    71281 gatggtgcgt cgaatggctt gaccgcgccg aatggtccct cgcagcagcg ggtcatccag
    71341 caggcgttgg cgagtgcggg tctgtcggtg tccgatgtgg atgccgtgga ggcgcatggg
    71401 accgggacca ggttgggtga tccgattgag gcgcaggctc tgattgctac gtatgggcgc
    71461 gatcgtgatc ccggtcggcc gttgtggttg gggtcggtga agtccaacat cggtcatacg
    71521 caggcggcgg cgggtgttgc cggtgtgatc aagatggtga tggcgatgcg gcacgggcaa
    71581 cttccgcgca cgctgcacgt ggatgcaccc tcctcgcagg tggattggtc ggcggggagg
    71641 gtccagctcc tgacggagaa cacgccctgg cccgacagtg gtcgcccctg tcgggtgggg
    71701 gtgtcgtcgt tcgggatcag cggcaccaac gcgcacgtca tcctggaaca gtccacgggg
    71761 cagatggatc aggcagcgga gccggattcg agtcctgttc tggatgttcc ggtggtgccg
    71821 tgggtggtgt cgggcaaaac acccgaagcg ctatccgccc aggcggcaac gttggcgacc
    71881 tatttggacc aaaatgttga tgtctcccct ctggacgttg ggatttcgct tgcggtgacc
    71941 cgttcggcgc tggatgagcg ggcggtggtg ctggggtcgg atcgtgacac gttgttgtct
    72001 ggcctgaatg cgctggctgc cggtcatgag gctgctggcg tggttacggg acctgtcggg
    72061 attggtggcc ggaccgggtt tgtgttcgcc ggtcaaggcg gtcagtggtt ggggatgggc
    72121 cgccggttgt actcggagtt tccggcgttc gccggtgctt tcgacgaagc atgcgccgag
    72181 ctcgatgcga acctggggag ggaagtcggg gttcgggatg tggtgttcgg ctccgacgag
    72241 tccttgctgg atcggacttt gtgggcgcag tcgggtttgt tcgcgttgca ggtcggtctc
    72301 tgggaattgt tgggtacgtg gggtgttcgg cccagcgtag tgctggggca ttcggtcggg
    72361 gagctagccg cggcgttcgc cgcaggtgtg ctgtcgatgg cggaggcggc tcggctggtg
    72421 gcgggtcgtg cgcggttgat gcaggcgttg ccttctggcg gtgccatgct ggcggtgtcc
    72481 gcgaccgagg cccgagtcgg cccgctgctc gatggggtgc gggatcgtgt tggtgtcgca
    72541 gcggttaacg ctccggggtc ggtggtgctt tccggtgacc gggatgtgct cgatggcatt
    72601 gccggtcggc tggacgggca aggtatccgg tcgaggtggt tgcgggtttc gcacgcgttt
    72661 cattcgcatc ggatggatcc gatgctggcg gagttcgccg agctcgcacg gagcgtggac
    72721 taccggtctc cacggctgcc gattgtctcg acgctgaccg gaaacctcga tgacgtgggc
    72781 gtgatggcta cgccggagta ttgggtgcgc caggtgcgag agcccgtccg cttcgccgac
    72841 ggtgtccagg cgcttgtgga ccaaggcgtc gacacgattg tggaactcgg tccggacggg
    72901 gcgttgtcga gcttggttca agagtgtgtg gcggagtccg ggcgggcgac ggggattccg
    72961 ttggtgcgga gagaccgtga tgaggtccga acggtgctgg acgctttggc gcagacccac
    73021 actcgtggtg gcgcggtgga ctgggggtca tttttcgctg gtacgagggc aacgcaagtc
    73081 gaccttccca cgtatgcctt ccaacgacag cggtactggc tggagccatc ggattccggt
    73141 gatgtgaccg gtgttggcct gaccggggcg gagcatccgc tgttgggtgc cgtggtgccg
    73201 gtcgcgggcg gcgatgaggt gctgctgacc ggcaggctgt cggtggggac gcatccgtgg
    73261 ctggcggaac accgcgtgct gggcgaagtc gtcgtccccg gcaccgcgtt gctggagatg
    73321 gcgtggcggg ccggtagcca ggtcggttgt gaacgtgtgg aggagctcac cttggaggca
    73381 ccgctggtcc tgccggagcg gggcgctgcg gcggtgcagt tggcggtggg ggctccggat
    73441 gaggccggcc ggcgcagttt gcagctctat tcccgaggcg ctgatgaaga cggcgactgg
    73501 cggcggattg cctccgggct gttggcccag gccaatgcgg tgccgccggc ggattcgacg
    73561 gcatggccgc cggacggcgc cgggcaggtc gatctggcgg agttctacga gcgcctcgcc
    73621 gagcgcggct tgacctacgg tccggtattc caagggctcc gcgccgcatg gcggcacggc
    73681 gacgatatct tcgccgaatt ggccgggtca ccagacgcct cgggtttcgg catccacccg
    73741 gcgctgctgg acgctgcact gcacgcgatg gcgcttggtg cttcgcccga ctcggaagcg
    73801 cgtctgccgt tttcctggcg tggcgcccag ctgtaccgcg ctgaaggagc agcgcttcgg
    73861 gtacggctct cgccgctggg ctccggtgca gtctcattga cgttggtgga tgccacaggg
    73921 cgacgagtcg ctgcggtgga atcgctttcg acgcgaccgg tctccaccga ccagatcggt
    73981 gccggtcgcg gcgatcaaga gcggctgctg cacgtcgagt gggtaaggtc ggctgaatct
    74041 gcggggatgt ctctgacctc ctgcgcggtg gtcggtttgg gcgaaccgga gtggcacgct
    74101 gcgctgaaga ccactggtgt ccaagtcgag tcccatgcgg accttgcttc gttggccacc
    74161 gaggttgcca agcggggttc agctcctggt gcggtcatcg tcccgtgccc gcgaccccga
    74221 gcgatgcagg agctgccgac cgccgcgcga agggcgacgc aacaggcgat ggcgatgctg
    74281 cagcaatggc ttgccgatga ccggttcgtc agtacgcgcc tgatcctgct gacgcatcgg
    74341 gcggtctccg cagttgctgg agaagacgtg ctcgacctgg tacacgcgcc gctgtggggc
    74401 ttggtccgca gcgcgcaagc ggagcacccg gaccgattcg ccttgatcga tatggacgac
    74461 gagcgagcat cgcagacggc actcgccgaa gcgctgactg cgggagaagc gcagctcgcg
    74521 gtgcggtcgg gagttgtgct ggcgccccgc ctcggccagg tgaaggtgag tggaggtgaa
    74581 gcgttcaggt gggatgaagg caccgtgctg gtcaccggcg gaaccggcgg gctcggggcc
    74641 ctgctcgcac gccatctggt cagcgcccac ggtgtgcggc acctgttgct cgcaagtcgc
    74701 cgtggtctgg cggcgcccgg agcggatgag ctggtggccg agctggagca ggccggcgcc
    74761 gacgtcgcgg tcgtcgcgtg cgactcggca gatcgggact cgcttgcgcg gctggtggcg
    74821 tcggtgcctg cggaaaaccc gttgcgggtg gtggtgcacg ccgccggtgt gctggatgac
    74881 ggtgtgctga tgtcgatgtc gccggagcgc ttggacgcgg tgttgcggcc caaagtggat
    74941 gccgcgtggt acctgcacga gctgactcgg gaactcggtc tgtcggcgtt cgtgttgttc
    75001 tcctcggtcg cgggcctgtt cggcggtgcg gggcagagca attacgctgc cggcaacgct
    75061 ttcctggatg ccttggcgca ttgccggcag gcccaggggc tgcccgcgct gtcgctggcc
    75121 tccgggctgt gggcgagtat cgatggaatg gcgggcgacc tcgctgcggc agatgtggag
    75181 cggctgtcgc gggcaggcat tggcccgctt tcggcaccgg gagggctggc cttgttcgac
    75241 gctgccgttg gctcggacga accgttgctg gcaccggtgc gactggatgt cgaagcactg
    75301 cgtgtgcagg cccgatccgt gcagacccgg attccggaaa tgctgcatgg catggcaatg
    75361 gggccaagcc gccgcactcc gttcacttcc agggttgagc cgttgcacga acggctggcc
    75421 ggattgtcgg agggcgaacg tcggcagcaa gtgctccagc gcgtccgcgc cgatatcgcg
    75481 gtggtactgg ggcacggcag gtcgagcgat gtggacatcg agaagccttt ggccgagctg
    75541 ggtttcgact cgctgacggc catcgaactc cgcaaccgtc tcgctaccgc caccggactg
    75601 cggcttcccg cgacgctggc cttcgaccac ggcactgcgg cggcactcgc ccagcacgtg
    75661 tgcgcgcagc taggcaccgc gaccgcgccg gcaccgaggc gaaccgacga caacgacgcc
    75721 acggagcccg tgaggtcgct cttccaacag gcgtatgcgg ctggccggat acttgacggg
    75781 atggatttgg tgaaggtcgc tgcccagttg cgaccggtgt tcggttcgcc tggcgagctg
    75841 gaatccctgc cgaaacccgt ccagctttcc cgtggtcccg aagagcttgc cttggtgtgc
    75901 atgccggcgc tgatcgggat gccgcccgca cagcagtacg cgcggatcgc cgccgggttc
    75961 cgcgatgtgc gggacgtttc ggtgatcccg atgcctggat tcattgcggg agaaccgctg
    76021 ccgtccgcca tcgaggtggc ggttcggacg caggcggagg cggtgctgca ggaattcgcc
    76081 gggggctcgt tcgtactggt cgggcattcc tccgggggct ggctggcgca cgaggtagcc
    76141 ggtgagctgg agcgtcgcgg ggtcgtcccg gccggggtcg tactgctgga cacctacatc
    76201 cccggtgaga tcacgccgag gttctccgtg gcgatggccc accggacgta tgagaagctc
    76261 gcgactttca cggacatgca ggatgtcggt atcaccgcga tgggcgggta cttccggatg
    76321 ttcaccgagt ggactccgac gccgatcggt gctccgacgc tgttcgtgcg gaccgaagat
    76381 tgcgtcgcag accctgaagg gcggccgtgg acagatgact cctggcggcc agggtggact
    76441 ctcgcggatg ccacggtcca ggtgccgggc gaccacttct cgatgatgga cgagcacgcc
    76501 gggtccaccg cacaggcagt cgcgagttgg cttgacaaac tcaaccagcg caccgctcgg
    76561 caacgctgac gggcgtcctt ttaggacctt ctgggcggca ccggccaccc cggcggtgcc
    76621 gccttccgtg gtccaggctc gccgatcttg acggcgcacg atgcgcggca cgcgcgctga
    76681 tcgtgattcc gctgccgctc gtggccatcg gcctggcgaa tcatgtcctt tcgggcaacg
    76741 tcaaacgaat tcgtccgagc ccgcattccg aggtgagggg cacccttggg tggctgagcc
    76801 gctcaagggt gcccctcacc tcgaaattcg tccgatttgg gcggtggacg caaccccggt
    76861 gggcgtggtg cgtctttctt gttgacagag cggtgagaag ccgctgacac acctgagagg
    76921 aaaaggggag catgatgctc aagcgccacc gtttgacgac cgccatcacc ggccttctgg
    76981 ggggagtact gctggtcagc ggctgcggaa ccgccgccgc acttcagtcc tcgccggcgc
    77041 ccgggcatga cgcgcgcaat gttggtatgg cctcgggcgg gggcggcggg gacatcggca
    77101 cgtcgaactg ctcggaggcc gatttcctcg ccaccgcgac accggtgaaa ggcgaccccg
    77161 gcagtttcat cgtggcgtac gggaaccggt cggacaagac ctgcacgatc aacggcggcg
    77221 tgccgaacct caagggcgtg gacatgagca actcgccgat cgaggacctg ccggtcgagg
    77281 acgtgcggct tcccgacgcg cccaaggaat tcaccctcca gcccggtcag agcgcgtacg
    77341 ccggcattgg catggtcctg gccgacagcg gcgacccgaa cgcccatgtc ctcaccgggt
    77401 tccagtcctc gctgccggac atgtccgagg cccagccggt caacgttctc ggcgacggca
    77461 acgtgaagtt cgccgcgaag tacctgcgag tcagctcgct ggtgtctacc gcagacgagc
    77521 tgcgctaaaa cccatgtgag tcccgcagat tcgacctcgc cgtgcggcgc ctccggcgaa
    77581 gcgtccgtac gtttgtcgtt gtgaccagcg ttgttcacgt ccgggcgcag cgctggtaca
    77641 tactcaggcg tctcgggcgc ctccaacggg gcctggcatc cggggccgtc gagtgcggcg
    77701 gcgctgacgc gttctctgtc gggcgttgtc acgccgccgg cctcgaaccg gtcccgcccc
    77761 gtcggagccg gtggtccagc gcggtgtggc ggcggccgga gccgacggtg cgcaccgcct
    77821 gcccgagggc ctttttcgaa ccgacgagga ccacgacctt cttggcccgg gtgaccgccg
    77881 tgtagagcag gttgcgctgc agcatcatcc aggcgcttgt ggtcaagggg atcaccacgc
    77941 acgggtattc gcttccctgc gaacgatgga tggtcaccgc gtaggcgtgg accagttcgt
    78001 cgagttctgt gaagtcgtag tcgatgtcct cgtcctcgtc ggttcgcacg gtcatggtct
    78061 gtgcttcgtt gtcgagggcg gacacgacgc cctgcgtgcc gttgaacacg ccgttggcgc
    78121 ccttgtcgta gttgttgcgg atctgcgtga ccttgtcgcc gacgcggaag atccgtccgc
    78181 cgaaccgccg ctctggcagg ccctccctgg ccggggtgat cgcttcctgc aacagctggt
    78241 tcagcgcgcc tgcacctgcg gggcctcgat gcatcggggc gaggacctgc acgtcggtgc
    78301 gcgggttgaa ccggaacttc cgcggaatcc ggcgggcgac gacgtcgacg gtgagctcgg
    78361 cggtcggttc gctttcctct acgtggaaca ggaagaagtc ggtcagcccg tgtgtcagcg
    78421 gatagtcccc ggcgttgatt cggtgcgcgt tggtcaccac cccggactcg gcggcctgcc
    78481 ggaacacctc gttgagccgc acgtgtggaa tcggggtgcc aggggcgagc agatcgcgca
    78541 gtacctcacc ggctccgacc gacgggagct ggtcgacgtc gccgaccagc agcaggtgcg
    78601 cgccgggcgc gatcgccttg gccagtttgt tggctaacag caggtcgagc atggacgcct
    78661 cgtcgaccac gacgaggtcg gcgtccagcg ggttgtcccg gtcgtaggcg gcgtccccgc
    78721 ccggctggag ttggagcagg cggtgcacgg tcgccgcgtc gtgtccggtg agctcggtca
    78781 gccgcttcgc cgctcgtccc gtcggcgcgg cgaggatcac cttggccttt ttcgcctgag
    78841 ctaatgcgat gatcgaccgc acggtgaagc tcttgccgca gcctggacct ccggtgagca
    78901 cggcgacctt ctcggtcagg gccagcttga cggcgcgctc ctgcgcctcg gcgagttcgg
    78961 caccggtagc gcggcgcaac cagtcgaggg ccttgtgcca atcgacgtcg gcgaagacgg
    79021 gcatccggtc cgcgctggtg ttcagcagcc gggacagctg gttggccagg gcgacttcgg
    79081 cgcggtggaa gggcacgagg tagatcgcga ccgtcggcac ctcgtcgtca tcggtgggga
    79141 tctcctcgcg gaccacacct tcctcggtga cgagttcggc gaggcattcg atcaccagcc
    79201 cggtgtcgac ggcgaggatc ttcaccgcct cggcgatcag ctcgttctcc ggcaggtagc
    79261 agttgccgtc gccggtggac tccgacagcg tgaactgaag gcccgccttt acccgctgcg
    79321 gggagtcgtg cgggattccc accgctttgg cgatggtgtc ggcggtcttg aaaccgattc
    79381 cccacacgtc gcctgccagc cggtatggct cttccttgac ggtccggatc gcgtcgtcgt
    79441 ggtactgctt gtagatcttc accgccagcg aggtcgagac gccgacgcct tgcaggaaga
    79501 tcatcacctc cttgatcgcc ttctgctcct cccacgcgtc ggcgatcagc ttcgtccgct
    79561 tcgggccgag cttggggacc tcgatcagcc gcgcgggttc ctgctcgatg acgtcgagcg
    79621 cggcgacgcc gaagtggtcg acgatcttct cggcgagttt ggggccgatg cccttgatca
    79681 ggccagaccc caggtagcgg cggatacctt gcacggtcgc aggcagcacg gtcgtgtagt
    79741 cgtcgacgtg gaactgccgc ccgtactggg ggtgcgaccc ccaccggccg cgcatgcgca
    79801 acgcctcgcc gggctgcgcg cccagcagcg cgccgacgac cgtcaccagg tcaccgcccc
    79861 ggccggtgtc gatccgcgcg acggtgtagc cgctctcctc gttggcgaac gtgatccgct
    79921 ccagcgtgcc ctccagcacc gcagtccacg tggccgactc ccgtcctttt tccaccgaca
    79981 acacgtatca cgaacggctg tcaagcaaac cggcggtcac cacatgcagc ggcatctccc
    80041 gaacgcctcg ggctccggcg tcagcgggtg ggcgttcgcg atgccttggt gcggccggtg
    80101 ggagttgtag attttttcgt cctcgcgcag ggcctggagt aggtgccgct ggctccagat
    80161 c
//
