BGC0000152 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0000152 (Aspergillus nidulans)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	59,725	sterigmatocystin	PKS	100%

BGC0000152 - Region 1 - T1PKS

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Location: 1 - 59,725 nt. (total: 59,725 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 59,726
Label		BGC0000152

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000152	0.60	Polyketide	sterigmatocystin	Aspergillus nidulans
BGC0002253	0.37	Polyketide	waikikiamide A, waikikiamide B, waikikiamide C, (+)-semivioxanthin, semivioxanthin	Aspergillus sp. FM242
BGC0001893	0.34	Other	abscisic acid	Botrytis cinerea B05.10
BGC0002236	0.34	Polyketide	8-methyldiaporthin	Aspergillus oryzae RIB40
BGC0002507	0.33	Polyketide	sporandol	Chrysosporium merdarium
BGC0000013	0.33	Polyketide	alternariol	Aspergillus nidulans FGSC A4
BGC0000677	0.32	Terpene	cyclooctatin	Streptomyces melanosporofaciens
BGC0001542	0.32	Polyketide	cercosporin	Cercospora zeina
BGC0002596	0.31	Polyketide	lecanoric acid, orsellinic acid	Claviceps purpurea 20.1
BGC0000011	0.30	Polyketide	sterigmatocystin	Aspergillus ochraceoroseus

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000152	1.00	Polyketide	sterigmatocystin	Aspergillus nidulans
BGC0002253	0.69	Polyketide	waikikiamide A, waikikiamide B, waikikiamide C, (+)-semivioxanthin, semivioxanthin	Aspergillus sp. FM242
BGC0001893	0.67	Other	abscisic acid	Botrytis cinerea B05.10
BGC0002236	0.67	Polyketide	8-methyldiaporthin	Aspergillus oryzae RIB40
BGC0001605	0.67	Terpene	gibberellin	Sinorhizobium fredii NGR234
BGC0002507	0.67	Polyketide	sporandol	Chrysosporium merdarium
BGC0000013	0.66	Polyketide	alternariol	Aspergillus nidulans FGSC A4
BGC0002221	0.66	Terpene	ent-kauren-16alpha-ol	Serpula lacrymans var. lacrymans S7.9
BGC0002721	0.66	Saccharide	α-hydroxynitrile glucoside, β-hydroxynitrile glucoside, γ-hydroxynitrile glucoside	Hordeum vulgare subsp. vulgare
BGC0002245	0.66	Terpene	terpestacin, preterpestacin 3, preterpestacin 2, preterpestacin 1	Bipolaris maydis C5

Similar known gene clusters from MIBiG 4.0

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 28582:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

stcA

PKS_AT (887..1185): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 100.0%; inactive: 62.5%; Methylmalonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 121.0
inactive: 48.0
Methoxymalonyl-CoA: 47.5
Methylmalonyl-CoA: 34.4
Isobutyryl-CoA: 17.7
2-Methylbutyryl-CoA: 15.4
fatty_acid: 11.8
Propionyl-CoA: 10.6
Ethylmalonyl-CoA: 10.1
CHC-CoA: 9.8
trans-1,2-CPDA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0

stcK

PKS_AT (1548..1733): pk

ATSignature: (unknown)

No matches above 50%

minowa: trans-1,2-CPDA

Prediction, score:

trans-1,2-CPDA: 0.0
inactive: 0.0
fatty_acid: 0.0
Propionyl-CoA: 0.0
Methylmalonyl-CoA: 0.0
Methoxymalonyl-CoA: 0.0
Malonyl-CoA: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0