BGC0000156: TAN-1612 biosynthetic gene cluster from Aspergillus niger
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Location: 1 - 13,275 nt. (total: 13,275 nt).
This entry is originally from NCBI GenBank JN257714.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000156
Short description TAN-1612 biosynthetic gene cluster from Aspergillus niger
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Iterative type I)
Loci
JN257714.1
via Heterologous expression, Gene expression correlated with compound production
Compounds
  • TAN-1612
  • 1-(2,3,5,10-tetrahydroxy-7-methoxy-4-oxo-1,2,3,4-tetrahydroanthracen-2-yl)pentane-2,4-dione
  • desmethyl TAN-1612
Species Aspergillus niger [taxonomy]
References
Chemical products information
TAN-1612 Evidence:
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C21H18O9
Chemical database entries
PubCHEM
ChemSpider
1-(2,3,5,10-tetrahydroxy-7-methoxy-4-oxo-1,2,3,4-tetrahydroanthracen-2-yl)pentane-2,4-dione Evidence:
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C20H20O8
desmethyl TAN-1612 Evidence:
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C20H16O9
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AEN83885.1
  • adaR
 501 - 3004 (+) AdaR
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    • AEN83886.1
    • adaD
    		 3412 - 4161 (-) O-methyltransferase
    • Tailoring
    • Knock-out Heterologous expression
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    • AEN83887.1
    • adaC
    		 4637 - 5881 (+) AdaC
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      • AEN83888.1
      • adaB
      		 6256 - 7260 (-) metallo-beta-lactamase-like thioesterase/Claisen cyclase
      • Scaffold biosynthesis
      • Knock-out Heterologous expression Activity assay
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      • AEN83889.1
      • adaA
      		 7894 - 13275 (+) AdaA
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        Biosynthesis information
        Annotation changelog

        Entry version: 4

        Date
        Changes
        Submitters
        Reviewers
        2022-10-07
        Update chemical activity to schema version 2.11
        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

        Entry version: 3

        Date
        Changes
        Submitters
        Reviewers
        2022-09-15
        Corrected gene identifiers
        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

        Entry version: 2

        Date
        Changes
        Submitters
        Reviewers
        2019-10-16
        Migrated from v1.4
        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

        Entry version: 1

        Date
        Changes
        Submitters
        Reviewers
        2015-06-12
        Submitted
        • (ID: BMUFDHMMOLZWQLUNJMQED2GP)
        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
        Detailed domain annotation
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