BGC0000160 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0000160 (Aspergillus terreus NIH2624)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	27,093	terreic acid	PKS	100%

BGC0000160 - Region 1 - T1PKS

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Location: 1 - 27,093 nt. (total: 27,093 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 27,094
Label		BGC0000160

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000160	1.00	Polyketide	terreic acid	Aspergillus terreus NIH2624
BGC0001276	0.69	Polyketide	6-methylsalicyclic acid	Aspergillus terreus
BGC0001286	0.31	Other	itaconic acid	Ustilago maydis
BGC0002670	0.28	Other	fosfonochlorin	Fusarium oxysporum f. sp. lycopersici 4287
BGC0002207	0.26	Other	psilocybin	Psilocybe cyanescens
BGC0001264	0.25	Polyketide	betaenone A, betaenone B, betaenone C	Phoma betae
BGC0000688	0.25	Terpene	copalyl diphosphate	Diaporthe amygdali
BGC0002229	0.25	Polyketide	6-MSA, aculin A	Aspergillus aculeatus ATCC 16872
BGC0000894	0.24	Other	citrinin	Monascus aurantiacus
BGC0000056	0.23	Polyketide	esperamicin	Actinomadura verrucosospora

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000160	1.00	Polyketide	terreic acid	Aspergillus terreus NIH2624
BGC0001276	0.89	Polyketide	6-methylsalicyclic acid	Aspergillus terreus
BGC0001286	0.64	Other	itaconic acid	Ustilago maydis
BGC0002670	0.62	Other	fosfonochlorin	Fusarium oxysporum f. sp. lycopersici 4287
BGC0002207	0.59	Other	psilocybin	Psilocybe cyanescens
BGC0001264	0.59	Polyketide	betaenone A, betaenone B, betaenone C	Phoma betae
BGC0000688	0.58	Terpene	copalyl diphosphate	Diaporthe amygdali
BGC0002229	0.58	Polyketide	6-MSA, aculin A	Aspergillus aculeatus ATCC 16872
BGC0000894	0.57	Other	citrinin	Monascus aurantiacus
BGC0000056	0.56	Polyketide	esperamicin	Actinomadura verrucosospora

Similar known gene clusters from MIBiG 4.0

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 27093:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ATEG_06275

PKS_AT (582..873): pk

ATSignature: Malonyl-CoA, Acetyl-CoA

Top 3 matches:: Malonyl-CoA: 66.7%; Acetyl-CoA: 66.7%; CE-Malonyl-CoA: 62.5%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 110.4
Ethylmalonyl-CoA: 89.6
Methoxymalonyl-CoA: 84.4
Isobutyryl-CoA: 74.8
Malonyl-CoA: 74.5
Acetyl-CoA: 72.5
2-Methylbutyryl-CoA: 57.9
Propionyl-CoA: 52.9
trans-1,2-CPDA: 40.9
Benzoyl-CoA: 37.2
fatty_acid: 35.4
3-Methylbutyryl-CoA: 32.9
CHC-CoA: 31.6
inactive: 12.6