BGC0000161: isoterrein biosynthetic gene cluster from Aspergillus terreus NIH2624
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Location: 399,827 - 432,585 nt. (total: 32,759 nt).
This entry is originally from NCBI GenBank CH476594.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000161
Short description isoterrein biosynthetic gene cluster from Aspergillus terreus NIH2624
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Iterative type I)
Loci
CH476594.1
399827 - 432585
via Knock-out studies, Heterologous expression, Gene expression correlated with compound production
Compounds
  • isoterrein
Species Aspergillus terreus NIH2624 [taxonomy]
References
Chemical products information
isoterrein Evidence:
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C8H10O3
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ATEG_00135
  • EAU38781.1
 399827 - 401540 (-) conserved hypothetical protein
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    • ATEG_00136
    • EAU38782.1
    		 402303 - 402958 (-) predicted protein
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      • ATEG_00137
      • EAU38783.1
      		 403467 - 404489 (+) conserved hypothetical protein
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        • ATEG_00138
        • EAU38784.1
        		 406533 - 408253 (+) conserved hypothetical protein
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          • ATEG_00139
          • EAU38785.1
          		 408831 - 411383 (-) transcription factor
          • Regulation
          • Knock-out Other in vivo study
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          • ATEG_00140
          • EAU38786.1
          		 412001 - 413380 (-) predicted protein
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            • ATEG_00141
            • EAU38787.1
            		 413999 - 416058 (+) predicted protein
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              • ATEG_00142
              • EAU38788.1
              		 416977 - 419033 (+) conserved hypothetical protein
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                • ATEG_00143
                • EAU38789.1
                		 420220 - 421386 (+) FAD-dependent monooxygenase
                • Tailoring
                • Knock-out
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                • ATEG_00144
                • EAU38790.1
                		 422324 - 425277 (-) predicted protein
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                  • ATEG_00145
                  • EAU38791.1
                  		 426061 - 432585 (+) hypothetical protein
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                    Biosynthesis information
                    Annotation changelog

                    Entry version: 3

                    Date
                    Changes
                    Submitters
                    Reviewers
                    2022-09-15
                    Add additional reference
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                    Entry version: 2

                    Date
                    Changes
                    Submitters
                    Reviewers
                    2019-10-16
                    Migrated from v1.4
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    2019-10-16
                    Updated compound(s) information (NPAtlas curation)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                    Entry version: 1

                    Date
                    Changes
                    Submitters
                    Reviewers
                    2015-06-12
                    Submitted
                    • (ID: ZUAEFEJPIFGA5SNZGJWBG3IU)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    Detailed domain annotation
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