BGC0000164: tetronomycin biosynthetic gene cluster from Streptomyces sp. NRRL 11266
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Location: 1 - 113,234 nt. (total: 113,234 nt).
This entry is originally from NCBI GenBank AB193609.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
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resistance
TTA codons
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Gene details
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General
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NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000164
Short description tetronomycin biosynthetic gene cluster from Streptomyces sp. NRRL 11266
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide
Loci NCBI GenBank: AB193609.1
Compounds
  • tetronomycin
Species Streptomyces sp. NRRL 11266 [taxonomy]
References
Chemical products information
tetronomycin
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C34H49Na1O8
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • BAE93717.1
  • tmn3
 1 - 901 (-) putative transcriptional regulator, LuxR family
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  • BAE93718.1
  • tmn4
 1056 - 1523 (+) hypothetical protein
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  • BAE93719.1
  • tmn5
 2518 - 5250 (+) putative transcriptional regulator, LuxR family
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  • BAE93720.1
  • tmn6
 5425 - 6216 (+) putative type II thioesterase
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  • BAF73715.1
  • tmn7a
 6245 - 6472 (+) acyl carrier protein
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  • BAE93721.1
  • tmn7
 6469 - 7347 (+) putative 2-oxoacid dehydrogenases acyltransferase
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  • BAE93722.1
  • tmnA1
 7524 - 22142 (-) type I polyketide synthase
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  • BAE93723.1
  • tmn10
 22261 - 22932 (-) putative DedA family membrane-associated protein
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  • BAF73716.1
  • tmn8
 23030 - 23602 (-) putative ribosomal protein L15P
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  • BAE93724.1
  • tmn9
 23752 - 25254 (-) putative FAD-dependent monooxygenase
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  • BAE93725.1
  • tmnVI
 25324 - 30048 (-) type I polyketide synthase
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  • BAE93726.1
  • tmnB
 30166 - 30591 (-) probable epoxide hydrolase
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  • BAE93727.1
  • tmn12
 30800 - 31702 (+) putative methyltransferase
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  • BAE93728.1
  • tmnAII
 31918 - 36894 (+) type I polyketide synthase
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  • BAE93729.1
  • tmnAIII
 36935 - 47161 (+) type I polyketide synthase
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  • BAE93730.1
  • tmnAIV
 47265 - 64238 (+) type I polyketide synthase
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  • BAE93731.1
  • tmnAV
 64292 - 82183 (+) type I polyketide synthase
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  • BAE93732.1
  • tmnC
 82294 - 83715 (-) putative tetronomycin epoxidase
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  • BAE93733.1
  • tmn14a
 83903 - 84145 (+) putative ferredoxin
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  • BAE93734.1
  • tmn14
 84250 - 85452 (+) putative cytochrome P450-like protein
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  • BAE93735.1
  • tmn15
 85457 - 86497 (+) putative 3-oxoacyl-(acyl-carrier-protein) synthase III
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  • BAE93736.1
  • tmn16
 86793 - 88694 (+) hypothetical protein
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  • BAE93737.1
  • tmn17
 88691 - 89728 (+) putative hydrolase or acyltransferase
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  • BAE93738.1
  • tmn18
 90184 - 90954 (+) putative pathway specific activator
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  • BAE93739.1
  • tmnDII
 91130 - 95656 (-) type I polyketide synthase-related protein
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  • BAE93740.1
  • tmnDI
 95688 - 103154 (-) type I polyketide synthase-related protein
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  • BAE93741.1
  • tmn20
 103414 - 105168 (+) putative acyltransferase family protein
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  • BAE93742.1
  • tmn21
 105209 - 105907 (-) putative TetR-family transcriptional regulator
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  • BAE93743.1
  • tmn22
 105907 - 107010 (-) putative membrane protein
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  • BAE93744.1
  • tmn23
 107270 - 108862 (+) hypothetical protein
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  • BAE93745.1
  • tmn24
 108964 - 110211 (+) hypothetical protein
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  • BAE93746.1
  • tmn25
 110322 - 112313 (+) hypothetical protein
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  • BAE93747.1
  • tmn26
 112404 - 113111 (+) hypothetical protein
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Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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