BGC0000166: tylactone biosynthetic gene cluster from Streptomyces fradiae
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Location: 1 - 43,280 nt. (total: 43,280 nt).
This entry is originally from NCBI GenBank U78289.1, but has been modified (see Modifications tab for details).

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core biosynthetic genes
additional biosynthetic genes
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Gene details
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General
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NRPS/PKS domains
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General information about the BGC
MIBiG accession BGC0000166
Short description tylactone biosynthetic gene cluster from Streptomyces fradiae
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide
Loci NCBI GenBank: U78289.1
Compounds
  • tylactone
Species Streptomyces fradiae [taxonomy]
References
Chemical products information
tylactone
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C23H38O5
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AAB66504.1
  • tylG
 816 - 14234 (+) tylactone synthase starter module and modules 1 & 2
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  • AAB66505.1
  • tylG_rename1
 14351 - 19945 (+) tylactone synthase module 3
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  • AAB66506.1
  • tylG_rename2
 20010 - 31199 (+) tylactone synthase modules 4 & 5
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  • AAB66507.1
  • tylG_rename3
 31232 - 36067 (+) tylactone synthase module 6
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  • AAB66508.1
  • tylG_rename4
 36249 - 41774 (+) tylactone synthase module 7
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  • AAB66509.1
  • tylG_rename5
 41771 - 43057 (+) tyl ORFX
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  • AAB66510.1
  • tylG_rename6
 43098 - >43280 (+) tyl ORFY
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Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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Modifications to original record
  • renamed CDS with name tylG at [14350:19945](+) to tylG_rename1 to avoid duplicates
  • renamed CDS with name tylG at [20009:31199](+) to tylG_rename2 to avoid duplicates
  • renamed CDS with name tylG at [31231:36067](+) to tylG_rename3 to avoid duplicates
  • renamed CDS with name tylG at [36248:41774](+) to tylG_rename4 to avoid duplicates
  • renamed CDS with name tylG at [41770:43057](+) to tylG_rename5 to avoid duplicates
  • renamed CDS with name tylG at [43097:>43280](+) to tylG_rename6 to avoid duplicates