BGC0000167: vicenistatin biosynthetic gene cluster from Streptomyces halstedii
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Location: 1 - 64,492 nt. (total: 64,492 nt).
This entry is originally from NCBI GenBank AB086653.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000167
Short description vicenistatin biosynthetic gene cluster from Streptomyces halstedii
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
AB086653.1
via
Compounds
  • vicenistatin
Species Streptomyces halstedii [taxonomy]
References
Chemical products information
vicenistatin Evidence:
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C30H48N2O4
Chemical database entries
NPAtlas
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • BAD08354.1
  • vinR1
 1 - 367 (-) putative transcriptional activator
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    • BAD08355.1
    • vinA
    		 695 - 1762 (+) dTDP-glucose synthase
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      • BAD08356.1
      • vinB
      		 1759 - 2730 (+) dTDP-glucose 4,6-dehydratase
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        • BAD08357.1
        • vinC
        		 2790 - 4049 (+) glycosyltransferase
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          • BAD08358.1
          • vinP2
          		 4412 - 11194 (+) polyketide synthase modules 4
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            • BAD08359.1
            • vinP3
            		 11260 - 21348 (+) polyketide synthase modules 5-6
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              • BAD08360.1
              • vinP4
              		 21411 - 32837 (+) polyketide synthase modules 7-8
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                • BAD08361.1
                • vinG
                		 33262 - 33972 (-) N-methyltransferase
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                  • BAD08362.1
                  • vinF
                  		 33980 - 35137 (-) aminotransferase
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                    • BAD08363.1
                    • vinD
                    		 35332 - 36801 (+) dTDP-4-keto-6-deoxyglucose 2,3-dehydratase
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                      • BAD08364.1
                      • vinE
                      		 36855 - 37841 (+) dTDP-4-keto-6-deoxyhexose 2,3-reductase
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                        • BAD08365.1
                        • vinH
                        		 38001 - 38498 (+) glutamate mutase S-chain
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                          • BAD08366.1
                          • vinI
                          		 38495 - 39904 (+) glutamate mutase E-chain
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                            • BAD08367.1
                            • vinJ
                            		 39990 - 40889 (+) proline iminopeptidase
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                              • BAD08368.1
                              • vinK
                              		 40886 - 41869 (+) malonyl-CoA-[acyl-carrier-protein] transacylase
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                                • BAD08369.1
                                • vinL
                                		 41987 - 42235 (+) acyl-carrier-protein
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                                  • BAD08370.1
                                  • vinM
                                  		 42289 - 43863 (+) non-ribosomal peptide synthetase
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                                    • BAD08371.1
                                    • vinN
                                    		 44156 - 45592 (+) non-ribosomal peptide synthetase
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                                      • BAD08372.1
                                      • vinO
                                      		 45589 - 46833 (+) decarboxylase
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                                        • BAD08373.1
                                        • vinP1
                                        		 47012 - 64492 (+) polyketide synthase modules 1-3
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                                          Biosynthesis information
                                          Annotation changelog

                                          Entry version: 4

                                          Date
                                          Changes
                                          Submitters
                                          Reviewers
                                          2022-10-07
                                          Update chemical activity to schema version 2.11
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                          Entry version: 3

                                          Date
                                          Changes
                                          Submitters
                                          Reviewers
                                          2022-09-15
                                          Updated bioactivity data
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                          Entry version: 2

                                          Date
                                          Changes
                                          Submitters
                                          Reviewers
                                          2019-10-16
                                          Migrated from v1.4
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          2019-10-16
                                          Updated compound(s) information (NPAtlas curation)
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                          Entry version: 1

                                          Date
                                          Changes
                                          Submitters
                                          Reviewers
                                          2015-06-12
                                          Submitted
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          Detailed domain annotation
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