BGC0000168: viridicatumtoxin biosynthetic gene cluster from Penicillium aethiopicum
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Location: 1 - 51,400 nt. (total: 51,400 nt).
This entry is originally from NCBI GenBank GU574477.1.

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core biosynthetic genes
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General
Compounds
Genes
Polyketide
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000168
Short description viridicatumtoxin biosynthetic gene cluster from Penicillium aethiopicum
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide (Tetracycline)
Loci NCBI GenBank: GU574477.1
Compounds
  • viridicatumtoxin
  • previridicatumtoxin
  • 5-hydroxyanthrotainin
  • 8-O-desmethylanthrotainin
Species Penicillium aethiopicum [taxonomy]
References
Chemical products information
viridicatumtoxin [synonyms: viriditoxin]
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C30H31N1O10
Chemical database entries
NPAtlas
PubCHEM
previridicatumtoxin
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C30H33N1O10
5-hydroxyanthrotainin
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C20H17N1O10
8-O-desmethylanthrotainin
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C19H15N1O9
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ADI24940.1
 442 - 1230 (+) unknown
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  • ADI24941.1
 1729 - 2172 (+) unknown
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  • ADI24942.1
 4973 - 5647 (+) unknown
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  • ADI24939.1
 6236 - 8992 (-) VrtR2
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  • ADI24938.1
 12194 - 13763 (+) VrtL
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  • ADI24937.1
 14679 - 16525 (+) VrtK
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  • ADI24936.1
 17107 - 18355 (+) VrtJ
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  • ADI24935.1
 18542 - 20138 (-) VrtI
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  • ADI24926.1
 20532 - 26109 (+) VrtA
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  • ADI24927.1
 26553 - 28864 (-) VrtB
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  • ADI24928.1
 29194 - 30645 (+) VrtC
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  • ADI24929.1
 31049 - 32254 (-) VrtD
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  • ADI24930.1
 32536 - 34433 (-) VrtE
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  • ADI24931.1
 34845 - 35561 (-) VrtF
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  • ADI24932.1
 35872 - 36795 (+) VrtG
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  • ADI24934.1
 36951 - 38255 (-) VrtH
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  • ADI24933.1
 38460 - 40607 (-) VrtR1
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  • ADI24943.1
 40894 - 42867 (+) unknown
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  • ADI24944.1
 43160 - 44658 (-) unknown
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  • ADI24945.1
 45248 - 46969 (-) unknown
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  • ADI24946.1
 48987 - 49874 (+) unknown
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  • ADI24947.1
 50142 - 51253 (-) unknown
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Polyketide-specific information
Subclass Tetracycline
Starter unit Malonamyl-CoA
Cyclic? yes
Release type
  • Claisen condensation
Polyketide-synthases
Genes Properties Modules
ADI24932.1
+
ADI24926.1 		Synthase subclass: Iterative type I
Thioesterases:
  • ADI24932.1 (Unknown)
Iterative PKS type: Non-reducing, C6-C11 first
Iteration counts: 8
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: BMUFDHMMOLZWQLUNJMQED2GP, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Corrected gene identifiers
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
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