BGC0000168: viridicatumtoxin biosynthetic gene cluster from Penicillium aethiopicum
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
View antiSMASH-generated output
Download Cluster GenBank file
Download region SVG
Location: 1 - 51,400 nt. (total: 51,400 nt).
This entry is originally from NCBI GenBank GU574477.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000168
Short description viridicatumtoxin biosynthetic gene cluster from Penicillium aethiopicum
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Iterative type I)
Loci
GU574477.1
via Knock-out studies, Enzymatic assays, Gene expression correlated with compound production
Compounds
  • viridicatumtoxin
Species Penicillium aethiopicum [taxonomy]
References
Chemical products information
viridicatumtoxin Evidence: Experimental values match with authentic standard [1]
Copy SMILES
C30H31N1O10
Chemical database entries
NPAtlas
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ADI24940.1
 442 - 1230 (+) unknown
    copy AA seq
    copy Nt seq
    • ADI24941.1
    		 1729 - 2172 (+) unknown
      copy AA seq
      copy Nt seq
      • ADI24942.1
      		 4973 - 5647 (+) unknown
        copy AA seq
        copy Nt seq
        • ADI24939.1
        		 6236 - 8992 (-) transcription factor
          copy AA seq
          copy Nt seq
          • ADI24938.1
          		 12194 - 13763 (+) MFS transporter
            copy AA seq
            copy Nt seq
            • ADI24937.1
            		 14679 - 16525 (+) cytochrome P450 oxygenase
              copy AA seq
              copy Nt seq
              • ADI24936.1
              		 17107 - 18355 (+) PLP-dependent protein
                copy AA seq
                copy Nt seq
                • ADI24935.1
                		 18542 - 20138 (-) Fe(II)-dependent oxygenase
                  copy AA seq
                  copy Nt seq
                  • ADI24926.1
                  		 20532 - 26109 (+) polyketide synthase
                    copy AA seq
                    copy Nt seq
                    • ADI24927.1
                    		 26553 - 28864 (-) VrtB
                      copy AA seq
                      copy Nt seq
                      • ADI24928.1
                      		 29194 - 30645 (+) aromatic prenyltransferase
                        copy AA seq
                        copy Nt seq
                        • ADI24929.1
                        		 31049 - 32254 (-) trans-isoprenyl diphosphate synthase
                          copy AA seq
                          copy Nt seq
                          • ADI24930.1
                          		 32536 - 34433 (-) cytochrome P450 oxygenase
                            copy AA seq
                            copy Nt seq
                            • ADI24931.1
                            		 34845 - 35561 (-) O-methyltransferase
                              copy AA seq
                              copy Nt seq
                              • ADI24932.1
                              		 35872 - 36795 (+) beta-lactamase-like hydrolase
                                copy AA seq
                                copy Nt seq
                                • ADI24934.1
                                		 36951 - 38255 (-) FAD-dependent oxidoreductase
                                  copy AA seq
                                  copy Nt seq
                                  • ADI24933.1
                                  		 38460 - 40607 (-) transcriptional factor
                                    copy AA seq
                                    copy Nt seq
                                    • ADI24943.1
                                    		 40894 - 42867 (+) unknown
                                      copy AA seq
                                      copy Nt seq
                                      • ADI24944.1
                                      		 43160 - 44658 (-) unknown
                                        copy AA seq
                                        copy Nt seq
                                        • ADI24945.1
                                        		 45248 - 46969 (-) unknown
                                          copy AA seq
                                          copy Nt seq
                                          • ADI24946.1
                                          		 48987 - 49874 (+) unknown
                                            copy AA seq
                                            copy Nt seq
                                            • ADI24947.1
                                            		 50142 - 51253 (-) unknown
                                              copy AA seq
                                              copy Nt seq
                                              Biosynthesis information
                                              Annotation changelog

                                              Entry version: next

                                              Date
                                              Changes
                                              Submitters
                                              Reviewers
                                              2024-06-05
                                              MIBiG v4 annotathon
                                              • (ID: G2MVQE7ERCZCXUNL7B4O5TI5)
                                              • (ID: BMUFDHMMOLZWQLUNJMQED2GP)
                                              • (ID: D44UGPXERIZAXNCG2VXZP5I3)
                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                              Entry version: 4

                                              Date
                                              Changes
                                              Submitters
                                              Reviewers
                                              2022-10-07
                                              Update chemical activity to schema version 2.11
                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                              Entry version: 3

                                              Date
                                              Changes
                                              Submitters
                                              Reviewers
                                              2022-09-15
                                              Corrected gene identifiers
                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                              Entry version: 2

                                              Date
                                              Changes
                                              Submitters
                                              Reviewers
                                              2019-10-16
                                              Migrated from v1.4
                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                              2019-10-16
                                              Updated compound(s) information (NPAtlas curation)
                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                              Entry version: 1

                                              Date
                                              Changes
                                              Submitters
                                              Reviewers
                                              2015-06-12
                                              Submitted
                                              • (ID: BMUFDHMMOLZWQLUNJMQED2GP)
                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                              Detailed domain annotation
                                              Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
                                              A domain glossary is available here, and an explanation of the visualisation is available here.
                                              Selected features only
                                              Show module domains
                                              Similar known gene clusters from MIBiG 4.0
                                              Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
                                              Click on reference genes to show details of similarities to genes within the current region.
                                              Click on an accession to open that entry in the MiBIG database.