BGC0000170 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0000170 (Aspergillus niger ATCC 1015)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	23,998	yanuthone D	PKS	100%

BGC0000170 - Region 1 - T1PKS

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Location: 1 - 23,998 nt. (total: 23,998 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 23,999
Label		BGC0000170

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000170	1.00	Polyketide	yanuthone D	Aspergillus niger ATCC 1015
BGC0002615	0.51	Terpene	4-oxomacrophorin A, macrophorin A, 5'-epimacrophorin B	Penicillium terrestre
BGC0001275	0.38	Polyketide	6-methylsalicyclic acid	Glarea lozoyensis
BGC0001273	0.37	Polyketide	asperlactone	Aspergillus ochraceus
BGC0001244	0.37	Polyketide	(-)-Mellein	Parastagonospora nodorum
BGC0000677	0.32	Terpene	cyclooctatin	Streptomyces melanosporofaciens
BGC0002610	0.32	Terpene	stellatic acid	Aspergillus stellatus
BGC0000798	0.31	Saccharide	dhurrin	Sorghum bicolor
BGC0002218	0.28	Terpene	(-)-Cyatha-3,12-diene	Dentipellis sp. KUC8613
BGC0000996	0.28	NRP, Polyketide	frontalamide B, frontalamide A	Streptomyces sp. SPB78

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000170	1.00	Polyketide	yanuthone D	Aspergillus niger ATCC 1015
BGC0002615	0.79	Terpene	4-oxomacrophorin A, macrophorin A, 5'-epimacrophorin B	Penicillium terrestre
BGC0001275	0.70	Polyketide	6-methylsalicyclic acid	Glarea lozoyensis
BGC0001273	0.69	Polyketide	asperlactone	Aspergillus ochraceus
BGC0001244	0.69	Polyketide	(-)-Mellein	Parastagonospora nodorum
BGC0000677	0.66	Terpene	cyclooctatin	Streptomyces melanosporofaciens
BGC0002610	0.65	Terpene	stellatic acid	Aspergillus stellatus
BGC0000798	0.64	Saccharide	dhurrin	Sorghum bicolor
BGC0002218	0.62	Terpene	(-)-Cyatha-3,12-diene	Dentipellis sp. KUC8613
BGC0000996	0.61	NRP, Polyketide	frontalamide B, frontalamide A	Streptomyces sp. SPB78

Similar known gene clusters from MIBiG 4.0

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 23998:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Me-ccmal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ASPNIDRAFT_44965

PKS_AT (586..877): mmal

ATSignature: Methylmalonyl-CoA, Malonyl-CoA

Top 3 matches:: Methylmalonyl-CoA: 75.0%; Malonyl-CoA: 75.0%; Ethylmalonyl-CoA: 70.8%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 111.9
Ethylmalonyl-CoA: 94.8
Methoxymalonyl-CoA: 91.0
Isobutyryl-CoA: 67.1
Malonyl-CoA: 58.2
trans-1,2-CPDA: 46.4
Benzoyl-CoA: 44.0
Propionyl-CoA: 40.9
2-Methylbutyryl-CoA: 40.5
Acetyl-CoA: 31.8
fatty_acid: 30.0
CHC-CoA: 16.5
3-Methylbutyryl-CoA: 16.1
inactive: 10.4