BGC0000171: 9-methylstreptimidone biosynthetic gene cluster from Streptomyces himastatinicus ATCC 53653
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Location: 1 - 52,580 nt. (total: 52,580 nt).
This entry is originally from NCBI GenBank FR878059.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Polyketide
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000171
Short description 9-methylstreptimidone biosynthetic gene cluster from Streptomyces himastatinicus ATCC 53653
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide (Other)
Loci NCBI GenBank: FR878059.1
Compounds
  • 9-methylstreptimidone
Species Streptomyces himastatinicus ATCC 53653 [taxonomy]
References
Chemical products information
9-methylstreptimidone
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C17H25N1O4
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • CCC21111.1
 1 - 1389 (-) putative peptide synthetase
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  • CCC21112.1
 1389 - 2429 (-) putative 3-dehydroquinate synthase
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  • CCC21113.1
 2426 - 3232 (-) putative Dhna-type fructose-1,6-bisphosphate aldolase
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  • CCC21114.1
 3487 - 4092 (+) putative tryptophan repressor binding protein
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  • CCC21115.1
  • smdA
 4106 - 5683 (+) drug resistance transporter
  • Transport
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  • CCC21116.1
  • smdB
 5637 - 6545 (+) lysr family transcriptional regulator
  • Regulation
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  • CCC21117.1
  • smdC
 6799 - 8133 (-) signal transduction histidine kinase
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  • CCC21118.1
  • smdD
 8130 - 8834 (-) two component transcriptional regulator
  • Regulation
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  • CCC21119.1
  • smdE
 8903 - 9667 (-) thioesterase
  • Scaffold biosynthesis
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  • CCC21120.1
  • smdF
 9983 - 10867 (+) malonyl coa-ACP transferase
  • Scaffold biosynthesis
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  • CCC21121.1
  • smdG
 10869 - 11126 (+) acyl carrier protein
  • Scaffold biosynthesis
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  • CCC21122.1
  • smdH
 11170 - 13161 (+) amidotransferase
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  • CCC21123.1
  • smdI
 13158 - 32300 (+) type-I polyketide synthases
  • Scaffold biosynthesis
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  • CCC21124.1
  • smdJ
 32300 - 32941 (+) putative flavoprotein decarboxylase
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  • CCC21125.1
  • smdK
 32938 - 34419 (+) putative 3-octaprenyl-4-hydroxybenzoate
  • Scaffold biosynthesis
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  • CCC21126.1
 34427 - 34969 (-) hypothetical protein
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  • CCC21127.1
 34986 - 37160 (-) hypothetical protein
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  • CCC21128.1
 37217 - 37678 (-) hypothetical protein
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  • CCC21129.1
 37798 - 39195 (-) putative monoxygenase
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  • CCC21130.1
 39195 - 40028 (-) putative ABC transporter inner membrane protein
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  • CCC21131.1
 40025 - 40912 (-) putative transporter permease
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  • CCC21132.1
 40919 - 42262 (-) putative ABC transporter extracellular membrane protein
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  • CCC21133.1
 42281 - 43489 (-) putative ABC transporter extracellular membrane protein
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  • CCC21134.1
 43528 - 44721 (-) putative acyl-CoA dehydrogenase
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  • CCC21135.1
 44718 - 45878 (-) putative alkanesulfonate monooxygenase
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  • CCC21136.1
 45915 - 47114 (-) putative acyl-CoA dehydrogenase
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  • CCC21137.1
 47121 - 47675 (-) putative NAD(P)H-dependent FMN reductase
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  • CCC21138.1
 47718 - 48935 (-) putative dibenzothiophene desulfurization enzyme C
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  • CCC21139.1
 48966 - 50105 (-) putative alkanesulfonate monooxyhenase
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  • CCC21140.1
 50634 - 51560 (+) putative LysR family transcriptional regulator
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  • CCC21141.1
 51547 - 52509 (-) putative G6PDH family F420-dependent oxidoreductase
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Polyketide-specific information
Subclass Other
Starter unit Propionyl-CoA
Cyclic? no
Polyketide-synthases
Genes Properties Modules
smdE Synthase subclass: Modular type I
Thioesterases:
  • smdE (Type II)
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AADADFAEMFE2AOMR24EUYNFH, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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