BGC0000180: legioliulin biosynthetic gene cluster from Legionella parisiensis
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Location: 4,550 - 31,415 nt. (total: 26,866 nt).
This entry is originally from NCBI GenBank KM222819.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
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Gene details
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General
Compounds
Genes
Polyketide
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000180
Short description legioliulin biosynthetic gene cluster from Legionella parisiensis
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide (Other)
Loci NCBI GenBank: KM222819.1
Compounds
  • legioliulin
Species Legionella parisiensis [taxonomy]
References
Chemical products information
legioliulin
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C19H14O3
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AIU36103.1
 4550 - 19033 (+) LglD
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  • AIU36104.1
 19026 - 23054 (+) LglE
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  • AIU36105.1
 23271 - 24191 (-) LglF
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  • AIU36106.1
 24506 - 25210 (-) LglG
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  • AIU36107.1
 25387 - 26676 (-) LglH
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  • AIU36108.1
 26679 - 27743 (-) LglI
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  • AIU36109.1
 28311 - 29612 (-) LglJ
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  • AIU36110.1
 29694 - 31415 (-) PAL phenylalanine ammonia lyase
  • Precursor biosynthesis
Heterologous expression
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Polyketide-specific information
Subclass Other
Cyclic? yes
Polyketide-synthases
Genes Properties Modules
AIU36103.1 Synthase subclass: Trans-AT type I
Module 1
Genes: AIU36103.1
Core domains: Thiolation (ACP/PCP)
Module 2
Genes: AIU36103.1
Core domains: Ketosynthase, Ketoreductase, Dehydratase, Thiolation (ACP/PCP)
KR-domain stereochemistry: Unknown
Module 3
Genes: AIU36103.1
Core domains: Ketosynthase, Thiolation (ACP/PCP)
Module 4
Genes: AIU36103.1
Core domains: Ketosynthase, Thiolation (ACP/PCP)
Module 5
Genes: AIU36103.1
Core domains: Ketosynthase, Ketoreductase, Thiolation (ACP/PCP)
KR-domain stereochemistry: Unknown
Module 6
Genes: AIU36103.1
Core domains: Ketosynthase, Dehydratase, Thiolation (ACP/PCP)
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: SCFYH7235HZBUM2XBV52IUHT, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Removed ketoreductase stereochemistry annotation from modules without ketoreductases
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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