BGC0000189: 3-(2'-hydroxy-3'-oxo-4'-methylpentyl)-indole biosynthetic gene cluster from Xenorhabdus bovienii SS-2004
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Location: 3,771,005 - 3,779,127 nt. (total: 8,123 nt).
This entry is originally from NCBI GenBank FN667741.1.

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core biosynthetic genes
additional biosynthetic genes
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000189
Short description 3-(2'-hydroxy-3'-oxo-4'-methylpentyl)-indole biosynthetic gene cluster from Xenorhabdus bovienii SS-2004
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Type III)
Loci
FN667741.1
3771005 - 3779127
via Enzymatic assays, Heterologous expression
Compounds
  • 3-(2'-hydroxy-3'-oxo-4'-methylpentyl)-indole
  • 3-(2'-hydroxy-3'-oxo-4'-methylhexyl)-indole
  • 3-(2'-acetoxy-3'-oxo-4'-methylpentyl)-indole
  • 3-(2'-acetoxy-3'-oxo-4'-methylhexyl)-indole
Species Xenorhabdus bovienii SS-2004 [taxonomy]
References
Chemical products information
3-(2'-hydroxy-3'-oxo-4'-methylpentyl)-indole Evidence:
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C14H17N1O2
Chemical database entries
NPAtlas
3-(2'-hydroxy-3'-oxo-4'-methylhexyl)-indole Evidence:
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C15H19N1O2
Chemical database entries
NPAtlas
3-(2'-acetoxy-3'-oxo-4'-methylpentyl)-indole Evidence:
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C16H19N1O3
Chemical database entries
NPAtlas
3-(2'-acetoxy-3'-oxo-4'-methylhexyl)-indole Evidence:
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C17H21N1O3
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • XBJ1_3894
  • CBJ83012.1
 3771005 - 3772681 (+) putative 3-oxoacyl-[acyl-carrier-protein] synthase
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    • XBJ1_3895
    • CBJ83013.1
    		 3772793 - 3772957 (+) conserved hypothetical protein
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      • XBJ1_3896
      • CBJ83014.1
      • adhC
      		 3773025 - 3774134 (+) alcohol dehydrogenase class III
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        • XBJ1_3897
        • CBJ83015.1
        • yaiM
        		 3774204 - 3775049 (+) putative esterase
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          • XBJ1_3898
          • CBJ83016.1
          		 3775114 - 3776094 (-) 3-oxoacyl-[acyl-carrier-protein] synthase III
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            • XBJ1_3899
            • CBJ83017.1
            		 3776248 - 3776379 (-) hypothetical protein
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              • XBJ1_3900
              • CBJ83018.1
              		 3776409 - 3777440 (-) acylating ketosynthases, acylation of the XclA-derived xenolcyloins with acetyl-, propionyl- or maleonyl-CoA
              • Activation / processing
              • Activity assay
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              • XBJ1_3901
              • CBJ83019.1
              		 3777430 - 3779127 (-) S-selective acyloin-like condensation enzyme
              • Activation / processing
              • Activity assay
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              Biosynthesis information
              Annotation changelog

              Entry version: 3

              Date
              Changes
              Submitters
              Reviewers
              2022-09-15
              Remove negative ketide_length
              • (ID: 3UOU7PODQJXIM6BEPUHHRRA5)
              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

              Entry version: 2

              Date
              Changes
              Submitters
              Reviewers
              2019-10-16
              Migrated from v1.4
              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
              2019-10-16
              Updated compound(s) information (NPAtlas curation)
              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

              Entry version: 1

              Date
              Changes
              Submitters
              Reviewers
              2015-06-12
              Submitted
              • (ID: SCFYH7235HZBUM2XBV52IUHT)
              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
              Detailed domain annotation
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