LOCUS       BGC0000193             14807 bp    DNA     linear   BCT 26-JUL-2016
DEFINITION  Streptomyces galilaeus aclacinomycin biosynthetic gene cluster,
            partial sequence.
ACCESSION   BGC0000193
VERSION     BGC0000193
KEYWORDS    .
SOURCE      Streptomyces galilaeus
  ORGANISM  Streptomyces galilaeus
            Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
            Streptomyces.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.2.0-924c3663(changed)
            Run date     :: 2022-11-07 17:39:33
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14807
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     gene            complement(<1..1986)
                     /gene="aknN"
     CDS             complement(<1..1986)
                     /codon_start=1
                     /gene="aknN"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: YcaO"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR03604"
                     /gene_kind="biosynthetic"
                     /product="AknN"
                     /protein_id="AAF73450.1"
                     /sec_met_domain="TIGR03604 (E-value: 5.8e-68, bitscore:
                     219.1, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="YcaO (E-value: 4.1e-80, bitscore: 259.7,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEDRVTTLGGEQIALLAPLLDGSRDLPGIVADAAPRLPAGLAER
                     LVTRLLDAGLLCAYPQDGADRPERAYRSLTGLQARSADARDAVLAAVDLTGDAESPLPE
                     AVSAAGLRAAAPGEHAALTLVLCHDYLDPRLSALDAEHRATGRGWLPVRANGTHLWIGP
                     FFSAGDGPCWSCLADRLRLRRRGEAYVQHRLGHSGPAVHRRAYLPAGRAAALQLALLEA
                     GKWLSGHRDTVQDSLWRLDTRTLESSRHPVRRRPQCSRCGDPLLVRDRVSAPVVLSSRP
                     VRDESGGGHRTFGPQEMLDRYGHLVDPVTGVVGEIRRDPRGPEFLNCFTRSRCRLGPRA
                     APPALHSPLRSPGSGKGVTELHARVSALAEALERCSGYFQGDEPRRRGSYRELAGLAVH
                     PDSVQLFDRRQFEDRRAWNRAHGPFHQVTEPFDEDAPIDWTPVWSLTERRQRLAPTSLL
                     YYNAPDADTGFCRATSNGAAAGTSLEDAVVHGCLELVERDAIALWWYNRTRQPGVTLDA
                     RDPWITRLRAVLRDLGRTVWALDLTSDLGIPVVAAVSVRTGGTAEDIVLGFGAHFDPRI
                     ALRRALTELSQMLPPLAQETAGDASAYTGTDPEAMRWFRHATTANQPYLLPAARRSARP
                     PASLRPPRDAAAQAGALVALLRRHGLE"
     source          1..14807
                     /db_xref="ATCC:31615"
                     /db_xref="taxon:33899"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces galilaeus"
                     /strain="ATCC 31615"
     subregion       1..14807
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0000193"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..14807
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /subregion_numbers="1"
                     /tool="antismash"
     protocluster    1..6986
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[<0:1986]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      <1..1986
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..6986
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     gene            2523..3341
                     /gene="aknO"
     CDS             2523..3341
                     /codon_start=1
                     /gene="aknO"
                     /gene_functions="regulatory (smcogs)
                     SMCOG1041:transcriptional regulator, SARP family (Score:
                     330.8; E-value: 3.6e-100)"
                     /gene_kind="regulatory"
                     /note="AknO"
                     /product="putative activator"
                     /protein_id="AAF73451.1"
                     /transl_table=11
                     /translation="MDIWLLGPLTAEVRGRSIVPTAAKPRQILALLAIHANRVLPVGTL
                     MEEIWGTEPPQSALATLHTYILQLRRRLTAAYGDEGGVSAKDVLVTQYGGYCWQAPTDS
                     VDVPRYERLVTAGRIATAEDRQEEASAHFREALALWRGSALVDVRIGPVLSIEVARLEE
                     SRLGVLERCLEADLRLGRHAELLAELTELTGRHPLHEGLHAQCMTALYRAGRSWQALDV
                     YQRLRRRLAEELGLSPSPRLQRLQQAVLSAEPWLDAPRYGGDPVFDRMIS"
     gene            complement(3355..4659)
                     /gene="aknP"
     CDS             complement(3355..4659)
                     /codon_start=1
                     /gene="aknP"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056:DegT/DnrJ/EryC1/StrS aminotransferase (Score:
                     367.6; E-value: 1.2e-111)"
                     /gene_kind="biosynthetic-additional"
                     /note="AknP"
                     /product="putative 3-dehydratase"
                     /protein_id="AAF73452.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 1.5e-103,
                     bitscore: 336.6, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSDTKALVLEQVREYHRQQQPGNFQPGVTPILSSGAVLDEEDRV
                     ALVEAALDLRIAAGAHSRRFESKFARHIGVRKAHLVNSGSSANLLALSALTSPRLGEQR
                     LRPGDEVITVAGGFPTTVNPILQNGLTPVFVDLELGTYNTTVEHVRAAISDRTRAIMIA
                     HTLGNPYQVAEIQQLATEHELFLIEDNCDAVGSTYQGRMTGTFGDLATVSFYPAHHITT
                     GEGGCVLTRNLELARIVESFRDWGRDCWCEPGEDNTCLKRFDYQLGNLPKGYDHKYIFS
                     HIGYNLKATDLQGALALSQLNKLPEFGAARRRNWQRLRDGLADVPGLLLPVATPGSDPS
                     WFGFVITVLPDATYTRRDLVAFLEERRIGTRRLFGGNLTRHPAYLGTPHRVAGDLRNSD
                     IITEQSFWIGVYPGITEEMTDYMRESIVEFVTKNG"
     gene            4821..5810
                     /gene="aknQ"
     CDS             4821..5810
                     /codon_start=1
                     /gene="aknQ"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079:oxidoreductase (Score: 245.1; E-value: 2.1e-74)"
                     /gene_kind="biosynthetic-additional"
                     /note="AknQ"
                     /product="putative 3-ketoreductase"
                     /protein_id="AAF73453.1"
                     /transl_table=11
                     /translation="MPKDTPRPVLRIGVLGCADIAVRRILPAIVEHPSVRLVALASRDG
                     ARAERLAARFGCAAVTGYKALLDREDINAVYVPLPPGMHHEWVTEALTAGKHVLVEKPL
                     STTYAQSVDLVAMAGRLGLALTENFMFLHHSQHEAVRAMTGEIGELRVFTSSFGVPPPH
                     PSSFRHDARLGGGALLDVGVYPLRAAQLHLAGELDVLGACLRVDEATGVDVAGSALLST
                     ATGVTAQLDFGFQHAYRSVYALWGSRGRLSVPRAFTPPREHRPVVRIEQQDRLTEVTLP
                     ADHQVGNALDAFASAVHSETVRASLGEALLRQALLVEQVRKAARVVSG"
     gene            complement(5921..6892)
                     /gene="aknR"
     CDS             complement(5921..6892)
                     /NRPS_PKS="Domain: NAD_binding_4 (73-179). E-value:
                     1.4e-13. Score: 42.3. Matches aSDomain:
                     nrpspksdomains_aknR_NAD_binding_4.1"
                     /codon_start=1
                     /gene="aknR"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score:
                     345.7; E-value: 4.4e-105)"
                     /gene_kind="biosynthetic-additional"
                     /note="AknR"
                     /product="putative dTDP-glucose 4, 6-dehydratase"
                     /protein_id="AAF73454.1"
                     /sec_met_domain="NAD_binding_4 (E-value: 3.4e-14, bitscore:
                     42.3, seeds: 102, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 8e-20, bitscore:
                     60.8, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="RmlD_sub_bind (E-value: 4.4e-21, bitscore:
                     64.9, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVLITGGAGFIGSHYVRSLLAGTLPGPRPSRVTVVDLLTYAGDT
                     GNLPLADPRLDFRRLDIRDLDALLTVVPGHDAVVHFAAETHVDRSLSEPAEFVRTNVLG
                     TQSLLEASLRGGVGTFVHVSTDEVYGSIAQGTWTEEAPLLPNSPYAASKAGSDLVARSY
                     WRTHGLDVRTTRCANNYGPRQHPEKLIPLFVTELLAGRPVPLYGDGGNVREWLHVDDHC
                     RAVHAVLTGGRPGEIYNIGGGTHLTNREMTAKLLALCGTDWSRVRQVPDRKGHDLRYAV
                     DDTKIREELGYRPLRSLDDGLREVVDWYRDRQTHRPEPAERV"
     aSDomain        complement(6356..6673)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_aknR_NAD_binding_4.1"
                     /evalue="1.40E-13"
                     /label="aknR_NAD_binding_4.1"
                     /locus_tag="aknR"
                     /protein_end="179"
                     /protein_start="73"
                     /score="42.3"
                     /tool="antismash"
                     /translation="GHDAVVHFAAETHVDRSLSEPAEFVRTNVLGTQSLLEASLRGGVG
                     TFVHVSTDEVYGSIAQGTWTEEAPLLPNSPYAASKAGSDLVARSYWRTHGLDVRTTRCA
                     NN"
     gene            complement(6880..8211)
                     /gene="aknS"
     CDS             complement(6880..8211)
                     /codon_start=1
                     /gene="aknS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1062:glycosyltransferase, MGT family (Score: 371.7;
                     E-value: 9e-113)"
                     /gene_kind="biosynthetic-additional"
                     /note="AknS"
                     /product="putative glycosyl transferase"
                     /protein_id="AAF73455.1"
                     /transl_table=11
                     /translation="MRVLLTSFALDAHFNGSVPLAWALRAAGHEVRVASQPALTASITA
                     AGLTAVPVGADPRLDEMVKGVGDAVLSHHADQSLDADTPGQLTPAFLQGWDTMMTATFY
                     TLINDDPMVDDLVAFARGWEPDLILWEPFTFAGAVAAKVTGAAHARLLSFPDLFMSMRR
                     AYLAQLGAAPAGPAGGNGTTHPDDSLGQWLEWTLGRYGVPFDEEAVTGQWSVDQVPRSF
                     RPPSDRPVVGMRYVPYNGPGPAVVPDWLRVPPTRPRVCVTLGMTARTSEFPNAVPVDLV
                     LKAVEGLDIEVVATLDAEERALLTHVPDNVRLVDHVPLHALLPTCAAIVHHGGAGTWST
                     ALVEGVPQIAMGWIWDAIDRAQRQQALGAGLHLPSHEVTVEGLRGRLVRLLDEPSFTAA
                     AARLRAEAESEPTPAQVVPVLERLTAQHRAREPRRPGGTSPCVS"
     gene            complement(8288..9619)
                     /gene="aknT"
     CDS             complement(8288..9619)
                     /codon_start=1
                     /gene="aknT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007:cytochrome P450 (Score: 214.4; E-value: 4.3e-65)"
                     /gene_kind="biosynthetic-additional"
                     /note="may participate in glycosylation of aclacinomycins;
                     similar to DnmQ"
                     /product="AknT"
                     /protein_id="AAF73456.1"
                     /transl_table=11
                     /translation="MQTQNAPETAENQQTDSELGRHLLTARGFHWIYGTSGDPYALTLR
                     AESDDPALLTRRIREAGTPLWQSTTGAWVTGRHGVAAEALADPRLALRHADLPGPQRHV
                     FSDAWSNPQLCHIIPLDRAFLHASDADHTRWARSASAVLGSAGGAPAEGVREHAGRVHR
                     EAADRTGDSFDLMADYSRPVATEAAAELLGVPAAQRERFAATCLALGVALDAALCPQPL
                     AVTRRLTEAVEDVRALVGDLVEARRTQPGDDLLSAVLHAGSSAASAGQDALAVGVLTAV
                     VGVEVTAGLINNTLESLLTRPVQWARLGENPELAAGAVEEALRFAPPVRLESRIAAEDL
                     TLGGQDLPAGAQVVVHVGAANRDPEAFLAPDHFDLDRPAGQGQLSLSGPHTALFGAFAR
                     LQAETAVRTLRERRPVLAPAGAVLRRMRSPVLGAVLRFPLTTSA"
     gene            complement(9643..10446)
                     /gene="aknU"
     CDS             complement(9643..10446)
                     /codon_start=1
                     /gene="aknU"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     201.4; E-value: 2.8e-61)"
                     /gene_kind="biosynthetic-additional"
                     /note="AknU"
                     /product="putative aklaviketone reductase"
                     /protein_id="AAF73457.1"
                     /transl_table=11
                     /translation="MNRAARPTVRGMSAIAEPTAPRGVIVTGGGTGIGRATAHAFADRG
                     DRVLVVGRTAATLAGTAEGHPGISVLTADLTDPDGPRAITDAALDALGRIDVLVNNAAT
                     GGFAGLAETEPEAAREQFDSNLLAPLLLTRQTLDALSADGGGTVLNIGSAGALGRRAWP
                     QNGVYGAAKAGLDFLTRTWAVELAPRGIRVLGLAPGVIDTGIGERSGMSREAYAGFLGQ
                     IAARVPAGRVGRPEDIAWWAVQLADPRAAYATGAVLAVDGGLSLT"
     gene            complement(10472..10906)
                     /gene="aknV"
     CDS             complement(10472..10906)
                     /codon_start=1
                     /gene="aknV"
                     /note="may participate in glycosylation of aclacinomycins;
                     similar to DnmW"
                     /product="AknV"
                     /protein_id="AAF73458.1"
                     /transl_table=11
                     /translation="MTAQAPTAPADVYAEVQHFYARQMRYLDSGEAETWAGTFTEDGSF
                     APPSLPEPVRGRPLLAEGARNAAAGLAAARETHRHWVGMLTVTPADDGSLTAESLVSIV
                     AVAQGGPARLHLVCTCRDVLVREGGRLLVRERVVTRDDRP"
     gene            11116..11895
                     /gene="aknW"
     CDS             11116..11895
                     /codon_start=1
                     /gene="aknW"
                     /note="AknW"
                     /product="putative cyclase"
                     /protein_id="AAF73459.1"
                     /transl_table=11
                     /translation="MRIIDLSSPVDAAGFEPDPVVHDVLGPKEAATHMSEEMREHFGID
                     FDPAELPEGEFLSLDRLQLTTHTGTHVDAPSHYGTRAAYRDGPPRHIDEMPLDWFFRPA
                     VVLDLSDQGTGAVGADVLRREMDRIGHTPSPMDIVLLRTGADAWAGTPKYFTDFTGLDG
                     SAVHLLLDLGVRVIGTDAFSLDAPFGDIITRYRATGDPSVLWPAHVIGRDREYCQVERL
                     AGLDRLPAAHGFRVACFPVRIAGAGAGWTRAVALVDE"
     gene            11957..12673
                     /gene="aknX2"
     CDS             11957..12673
                     /codon_start=1
                     /gene="aknX2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1248:methyltransferase (Score: 216.8; E-value:
                     5.4e-66)"
                     /gene_kind="biosynthetic-additional"
                     /note="AknX2"
                     /product="putative aminomethylase"
                     /protein_id="AAF73460.1"
                     /transl_table=11
                     /translation="MYGRELADVYEAIYRSRGKDWGQEAADVSRIITERRPGAGSLLDV
                     ACGTGAHLSVFSTLFEVAEGLEIAEPMRRLAEQRLPGTTVHAGDMRDFRLPRTYDAVSC
                     MFCAIGYLETLDDMRAAVRSMAAHLEPGGVLVVEPWWFPENFIEGYVAGDLAREEHRTI
                     ARISHTTRKGRATRMEVRFTVGDAAGIQQFTEIDVLTLFTRDEYTAAFTDAGCSVEFLE
                     DGPTGRGLFVGVREQR"
     gene            complement(12686..13561)
                     /gene="aknY"
     CDS             complement(12686..13561)
                     /codon_start=1
                     /gene="aknY"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 295.9; E-value:
                     5.1e-90)"
                     /gene_kind="biosynthetic-additional"
                     /note="AknY"
                     /product="putative dTDP-1-glucose synthase"
                     /protein_id="AAF73461.1"
                     /transl_table=11
                     /translation="MKGIILAGGSGTRLHPITVSVSKQLLPVGDKPMIYYPLSVLMLAD
                     IREILLICTERDLEQFRRLLGDGSQLGLRIDYAVQNRPAGLADAFVIGADHVGDDDVAL
                     VLGDNIFHGHHFYDLLQSNVHDVQGCVLFGYPVEDPERYGVGETDASGQLVSLEEKPLR
                     PRSDLAITGLYLYDNEVVDIAKNLRPSPRGELEITDVNRNYLARGRARLVDLGRGFAWL
                     DAGTPESLLQATQYVRTLEERQGVRIACVEEVALRMGFIDADMCHRLGEQMSQSGYGRY
                     VMAVAREFSG"
     gene            13784..>14807
                     /gene="aknZ"
     CDS             13784..>14807
                     /NRPS_PKS="Domain: Aminotran_5 (38-181). E-value: 1.8e-09.
                     Score: 28.8. Matches aSDomain:
                     nrpspksdomains_aknZ_Aminotran_5.1"
                     /codon_start=1
                     /gene="aknZ"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056:DegT/DnrJ/EryC1/StrS aminotransferase (Score:
                     372.1; E-value: 5.2e-113)"
                     /gene_kind="biosynthetic-additional"
                     /note="AknZ"
                     /product="putative aminotransferase"
                     /protein_id="AAF73462.1"
                     /transl_table=11
                     /translation="MTTLVWDYLQEYENERADILDAVETVFSSGRLVLGDSVRGFEEEF
                     AAYHGAAHCVGVDNGTNAIKLALQALGVGPGDEVVTVSNTAAPTVVAIDSVGATPVFVD
                     VHPDSYLMDTEQVEAALTPRTRCLLPVHLYGQCVDLAPLERLAAEHDLFLVEDCAQAHG
                     ARRAGRLAGTTGDAAAFSFYPTKVLGAYGDGGAVVTSRDDTHRALRRLRYYGMEERYYV
                     VGTPGHNARLDEVQAEILRRKLRRLDTYIEGRRAVARRYEDGLGDTGLVLPHTVPGNEH
                     VYYVYTVRHPRRDDIIKALKAYDIELNISYPWPVHTMSGFAHLGYGKGSLPVTEDLAGQ
                     I"
     aSDomain        13898..14326
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_aknZ_Aminotran_5.1"
                     /evalue="1.80E-09"
                     /label="aknZ_Aminotran_5.1"
                     /locus_tag="aknZ"
                     /protein_end="181"
                     /protein_start="38"
                     /score="28.8"
                     /tool="antismash"
                     /translation="RGFEEEFAAYHGAAHCVGVDNGTNAIKLALQALGVGPGDEVVTVS
                     NTAAPTVVAIDSVGATPVFVDVHPDSYLMDTEQVEAALTPRTRCLLPVHLYGQCVDLAP
                     LERLAAEHDLFLVEDCAQAHGARRAGRLAGTTGDAAAFS"
ORIGIN
        1 ctcgaggccg tgccggcgca gcagggcgac gagggccccg gcctgtgccg cggcgtcgcg
       61 gggaggccgc agcgaggcag ggggccgggc ggaccggcgc gccgcgggca ggagatacgg
      121 ctggtttgcc gtggtggcgt gccggaacca gcgcatggcc tcggggtccg tgccggtgta
      181 cgcggaggcg tcgccggccg tctcctgcgc caacggcggg agcatctggc tgagttcggt
      241 gagagcccgg cgcagggcga tacgcggatc gaagtgcgcg ccgaagccca gcacgatgtc
      301 ctcggcggtg ccgcccgtcc gcaccgacac ggcggcgacc acgggaatgc cgagatcgga
      361 cgtgaggtcg agggcccaca ccgtcctgcc cagatcgcgc aggacggccc ggagccgcgt
      421 gatccacgga tcccgcgcgt ccagggtcac gccgggctgg cgcgtgcggt tgtaccacca
      481 cagggcgatc gcgtcccgtt ccacgagttc caggcagccg tgcacgacgg cgtcctccag
      541 gctcgttccg gcggcggctc cgttggacgt ggcccggcag aagccagtgt ccgcgtccgg
      601 ggcgttgtag tagagcagac tcgtgggcgc gagccgctgc cgccgctcgg tcagtgacca
      661 gacgggggtc cagtcgatcg gggcgtcctc gtcgaagggc tcggtcacct ggtggaaggg
      721 accgtgcgcg cggttccacg cccgccggtc ctcgaactgt ctgcggtcga agagctggac
      781 gctgtccgga tgcacggcga gaccggccag ctcgcggtaa ctgccgcgcc ggcgcggttc
      841 gtcgccctgg aagtagccgc tgcaccgctc cagcgcctcg gccagcgcgc tgaccctggc
      901 gtggagttcg gtgacgccct tgccggatcc cgggctgcgc agcggggagt ggagcgccgg
      961 cggtgcagcg cggggtccca gacggcagcg cgaccgcgtg aagcagttga ggaactccgg
     1021 tccgcgcgga tcccggcgga tctcgccgac aacgccggtg acggggtcca cgagatggcc
     1081 gtagcggtcc agcatctcct gcggaccgaa cgtgcggtga ccaccgccgc tctcgtcccg
     1141 caccggccgg gaggacagca ccacgggtgc cgagacccgg tcgcgtacca gcagcggatc
     1201 gccgcagcgg gagcactgcg ggcggcgccg cacgggatgg cgactgctct ccagcgtgcg
     1261 ggtgtccagg cgccagaggc tgtcctgcac cgtgtcgcgg tgtccggaga gccactttcc
     1321 ggcttccagc agggccagtt gcagggccgc ggcacgcccc gcgggcaggt aggcccgccg
     1381 gtgcacggcc ggaccgctgt gccccagccg gtgctgcacg tacgcctcac cgcgccggcg
     1441 cagccggagc cggtccgcca gacagctcca gcaggggccg tcgccggcgg agaagaacgg
     1501 gccgatccac aggtgggtgc cgttggcccg gacgggcagc cagccgcgtc ccgtcgcgcg
     1561 gtgctccgcg tccagggcac tcagccgcgg gtcgaggtag tcgtgacaga gcaccagggt
     1621 cagagcggcg tgctcgcccg gtgccgcggc gcgcagcccc gccgcggaca cggcctcggg
     1681 cagcggggat tccgcgtcac cggtgaggtc gaccgcggcc aggaccgcgt cccgcgcgtc
     1741 ggcggaccgc gcctgaagac cggtgaggga ccggtaggcc cgttcggggc ggtcggcccc
     1801 gtcctgggga taggcgcaca gcagtcccgc gtccagcagc cgggtcacga gccgctcggc
     1861 gagtccggcc ggcagccggg gtgccgcgtc ggcgacgatg cccggcagat cgcggctgcc
     1921 gtcgagcagc ggggccagca gggcgatctg ctccccgccc agcgtggtca cccggtcctc
     1981 ggtcatcagg tagacgggct ctcccggccg cgactcgacc cgcagatgcg gtgcgaaccc
     2041 cagccggggg agcccgttgc caggggccgt acggctcatc gagacgcagg gccgccgacc
     2101 gtggccgacg gggtgctgga aaggggagcc cagcagatac agatcgcgct gtccgcgtgc
     2161 tccccgggac cgttgccgaa ctccgtgatg acgagatcgt cggcgaactc ggcggctgcc
     2221 gcgtcacctt ccaggagggg cgtgatccgt gacatgtgtg ctccttgtcg ctgtcggccg
     2281 gctgctgtga gtagtgctct ggccctggtt cgagctgtgc actgccgtca tccttacggc
     2341 ccgtcagggc ggctgccagt gcgtctggca taccgtgcct atgaggttta cacatcttgc
     2401 acatacgttc ctcatgtgcc tgttcgggtt cagggcactg gttgattgcc gaagtggcca
     2461 gcaagactcc ctgagcatgg agctcttcgc ggtgctccgt cgaccagatg ggggagaaga
     2521 acgtggacat atggttgctg ggaccgctga cggccgaggt gcggggcagg tcgatcgtgc
     2581 ccaccgcggc gaaaccccga cagatcctcg ccctgctcgc catccacgcc aatcgcgtcc
     2641 tgcccgtcgg gaccctgatg gaggagatct ggggcaccga gccgccccag agcgccctcg
     2701 ccaccctgca cacgtacatc ctccagctgc gccgccggct gaccgctgcc tacggtgacg
     2761 aggggggcgt gtccgccaag gacgtcctcg tcacccagta cggcggctac tgctggcagg
     2821 cgcccacgga ctccgtggac gtaccgcgct acgaacggct cgtcaccgcc ggacggatcg
     2881 ccaccgccga ggaccgccag gaggaggcgt cggcccactt ccgtgaggca ctcgcgctct
     2941 ggcgggggtc cgcgctggtg gacgtgcgga tcggaccggt cctgagcatc gaggtggcgc
     3001 ggctggagga gagcaggctc ggcgtgctgg agcgctgcct ggaggcggac ctgaggctgg
     3061 gacgccacgc ggagctgctg gccgaactca ccgaactcac cgggcgccat ccgctgcacg
     3121 agggcctgca cgcccagtgc atgacggcgc tgtaccgggc gggccgctcc tggcaggcgc
     3181 tggacgtcta ccagaggctg cgccgccggc tggcggagga actcggactc tccccgtcgc
     3241 cgcgcctgca gcgtctgcag caggcggtgc tctcggcgga gccctggctg gacgcgccca
     3301 ggtacggagg ggacccggtg ttcgaccgga tgatcagctg accgtcccgg cggctcagcc
     3361 gttcttggtg acgaactcga cgatggactc ccgcatgtag tcggtcatct cctccgtgat
     3421 gcccggatac accccgatcc agaagctctg ctcggtgatg atgtcggagt tgcgcagatc
     3481 gcccgccacc cggtgcggcg tgccgaggta cgccggatgg cgggtgaggt tgccgccgaa
     3541 cagccgccgt gtgccgatcc gccgttcctc caggaaggcg accaggtcac ggcgggtgta
     3601 ggtggcgtcg ggcaggaccg tgatcacgaa cccgaaccag ctgggatcgc tgcccggtgt
     3661 cgcgaccggc agcagcagac cggggacgtc ggcgagcccg tcccgcagcc gctgccagtt
     3721 gcgccgccgg gccgcgccga actccggcag cttgttcaac tggctgagtg ccagcgcccc
     3781 ttgcagatcg gtcgccttca ggttgtaacc gatgtgggag aagatgtact tgtggtcgta
     3841 gcccttgggg agattaccca gctggtagtc gaaccgcttg aggcaggtgt tgtcctcgcc
     3901 cggttcgcac cagcagtccc ggccccagtc gcggaacgac tcgacgatgc gggccagttc
     3961 gaggttgcgg gtcagtacgc agcccccctc gcccgtggtg atgtggtggg caggatagaa
     4021 actgaccgtt gccaggtccc cgaaggtccc cgtcatacgt ccctggtagg tcgagcccac
     4081 cgcgtcgcag ttgtcctcga tcaggaacag ctcgtgctcg gtggccagtt gctggatctc
     4141 cgccacctgg taggggttgc cgagggtgtg cgcgatcatg atggcccggg tccggtccga
     4201 gatcgccgcc cgcacgtgct ccaccgttgt gttgtacgta ccgagttcca ggtccacgaa
     4261 cacgggcgtc agcccgttct ggaggatcgg gttcaccgtg gtggggaatc cgccggccac
     4321 cgtgatcacc tcgtcacccg gacgcagccg ctgctcaccg agccggggag aggtcagcgc
     4381 agagagcgcc agcaggttcg ccgaggaccc cgagttcacc aggtgcgcct tgcgtacgcc
     4441 gatgtggcgg gcgaatttgc tctcgaagcg ccgggagtgg gctccggccg cgatccgcag
     4501 atccagggcg gcctccacca gggcgacccg gtcctcctcg tccaggacgg cgcccgagga
     4561 gaggatgggc gtcactccgg gctggaaatt ccctggctgc tgctgccggt gatactcgcg
     4621 aacctgctcc aggaccagag ccttggtgtc cgacgtcata gccgtccctc cgtaaggatt
     4681 gcctcgccga ccatgctggc ccggatcggt cgaggagccg tggagtcccg gccgaaggcc
     4741 ctgctccagt gggcttcaag gggccttcga cctgccgtgg ctagcgtgtc cggcgacgca
     4801 tcgaactggt gaggtggcag atgccgaagg acactccacg gcccgtactc cgcatcgggg
     4861 ttctgggctg tgccgatatc gcggtgcgcc ggatcctgcc cgcgatcgtg gagcatccgt
     4921 cggtccggct ggtcgctctg gcgagccggg acggggcgcg cgccgaacgg ctcgcggccc
     4981 gtttcggatg cgcggcggtg accggctaca aggcgctgct ggaccgtgag gacatcaacg
     5041 ccgtctacgt tcccctgccg cccggcatgc accacgaatg ggtcaccgaa gcgctgacgg
     5101 cgggcaagca cgtgctggtg gagaagccgc tcagcacgac gtacgcgcag agcgtcgacc
     5161 tggtggcgat ggccggccgg ctcggcctcg cgctcaccga gaacttcatg ttcctgcacc
     5221 actcgcagca cgaggcggtc cgggccatga ccggcgagat cggggaactg cgggtcttca
     5281 ccagttcctt cggcgtgccg ccgccccacc cctcgtcctt ccggcacgac gcgcggctcg
     5341 gcggcggcgc cctgctggac gtcggtgtct atccgctgcg cgcggcccag ctccacctcg
     5401 ccggggaact cgacgtgctg ggcgcctgtc tgcgcgtgga cgaggcgacc ggcgtcgacg
     5461 tcgcgggaag cgcgctgctg tccacggcga cgggtgtgac cgcgcagctc gacttcggct
     5521 tccagcacgc gtaccggtcc gtgtacgcgc tgtggggcag ccgcggcagg ctgagcgtgc
     5581 cgcgggcctt caccccgccc cgtgagcacc gcccggtggt ccgtatcgaa cagcaggacc
     5641 gtctcaccga agtgacgctg cccgccgatc accaggtggg caacgcgctc gacgcgttcg
     5701 cctcggcggt gcactcggag accgtccgtg cctccctggg ggaggcgctg ctgcgtcagg
     5761 cgctcctggt cgagcaggta cgcaaagccg cgcgggtcgt cagcggctga gccccccgga
     5821 cgctttgcgg gcgcctgacg cccgcacgac gagagaaggc cggggcgcga aggcgccggc
     5881 tctcctcaca ctcctcgcgg tcgcgccccg ccggggcggc tcagacccgc tcggccggtt
     5941 ccggccggtg ggtctgccgg tcgcggtacc agtcgacgac ctcgcgcaga ccgtcgtcca
     6001 gggaccgcag cggccggtag ccgagttctt cgcggatctt cgtgtcgtcc accgcgtacc
     6061 gcaggtcgtg gcccttgcgg tcgggcacct ggcggaccct ggaccagtcg gtgccgcaca
     6121 gcgcgagcag cttggccgtc atctcacggt tcgtcagatg ggtaccgccg ccgatgttgt
     6181 agatctcgcc gggccggcca ccggtcagca ccgcgtggac ggcccggcag tggtcgtcca
     6241 cgtgcagcca ttccctgacg ttgcctccgt cgccgtacag cggcaccggc cggccggcca
     6301 gcagttcggt gacgaacagc gggatgagct tctccgggtg ctgacggggg ccgtagttgt
     6361 tggcgcagcg ggtcgtgcgc acatcgaggc cgtgggtgcg ccagtaggac cgtgcgacca
     6421 ggtcgcttcc cgccttcgag gccgcgtagg gggagttggg gagcagcggc gcctcctccg
     6481 tccaggtgcc ctgcgcgatc gatccgtaga cctcgtccgt ggagacgtgc acgaacgtgc
     6541 cgaccccgcc gcgcaggctc gcctccagca gcgactgggt gcccagtacg ttggtgcgga
     6601 cgaactccgc cggctcgctc agcgaacggt cgacatgggt ctcggccgcg aagtgtacga
     6661 ccgcgtcgtg gccggggacc accgtcagca gcgcgtccag gtcgcggatg tcgagccggc
     6721 ggaagtccag ccggggatcg gccaggggca gattgccggt gtctcccgcg tacgtgagca
     6781 ggtcgacgac ggtgacccgg ctcgggcggg gaccgggcag ggtccccgcc agcagggaac
     6841 ggacgtagtg ggatccgatg aaaccggcgc cgccggtgat caggacacgc atggcgacgt
     6901 acctccgggg cgtcggggtt cacgggcgcg gtgctgggcg gtcagccgtt ccagtacggg
     6961 gacgacctgc gccggggtcg gttcggactc ggcctcggcc cgcaggcggg cggccgccgc
     7021 ggtgaacgag ggctcgtcga ggagccggac gagcctgccg cgcagtccct ccaccgtcac
     7081 ctcgtgcgag gggagatgga ggcccgcgcc gagtgcctgc tgacgctgcg cgcggtcgat
     7141 cgcgtcccag atccagccca tggcgatctg cggcacaccc tcgaccagcg ccgtcgacca
     7201 ggtgccggcg ccgccgtggt ggacgatggc cgcgcaggtc ggcagcagcg cgtgcagcgg
     7261 cacatggtcc accagacgca cattgtcggg gacatgggtc agcagtgccc gttcctcggc
     7321 gtcgagggtg gcgaccacct cgatgtccag cccctcgacc gccttgagga cgaggtcgac
     7381 cgggacggcg ttggggaact ccgaggtccg ggccgtcatg cccagggtga cgcagacgcg
     7441 ggggcgggtc ggcgggacgc gcagccagtc gggtacgacg gcaggccccg gcccgttgta
     7501 ggggacgtag cgcatgccca cgaccgggcg gtccgacggc gggcggaagc tgcgcggcac
     7561 ctggtccacc gaccactgtc ccgtcaccgc ctcctcgtcg aaggggacgc cgtagcggcc
     7621 gagcgtccac tccagccact ggccgagtga gtcgtcgggg tgcgtcgtcc cgttcccccc
     7681 ggccgggccc gccggggcgg cgccgagctg ggcgaggtag gcccgccgca tggacatgaa
     7741 gaggtccgga aaggacagca gccgggcgtg ggccgcgccg gtcaccttcg cggccaccgc
     7801 gccggcgaag gtgaacggct cccacaggat caggtccggt tcccagccgc gggcgaacgc
     7861 gacgaggtcg tcgaccatcg gatcgtcgtt gatcagggtg tagaaggtgg cggtcatcat
     7921 cgtgtcccag ccctggagaa aggccggggt gagctgtccg ggggtgtcgg cgtcgagcga
     7981 ctggtcggcg tggtgggaca gcacagcgtc gcccacgccc ttgaccatct cgtccagccg
     8041 ggggtccgcg cccaccggca cggcggtcag cccggccgcc gtgatgctcg ccgtcagcgc
     8101 gggctggctc gccacccgca cctcgtgccc ggcggcccgc aacgcccagg ccagcggcac
     8161 ggacccgttg aagtgagcgt ccagcgcgaa ggatgtcagg agaacccgca tggtcggtcc
     8221 tttctctgcg gctcggcttt cggcggctcg caactcgggc cgcggcacgc cgggccccgg
     8281 cgtgccgtca cgcggaggtg gtcaggggga agcgcagcac cgcgcccagc acgggggaac
     8341 gcatccgccg caggaccgcg ccggccggcg cgagcacggg ccggcgctcc cgcagcgtgc
     8401 ggaccgcggt ctccgcctgg agccgggcga acgccccgaa gagcgcggtg tgcgggccgg
     8461 agagcgacaa ctgcccctgc ccggcgggac ggtcgaggtc gaagtggtcc ggggccagga
     8521 acgcctcggg gtcccggttc gccgcaccga catggacgac gacctgggcg ccggccggga
     8581 ggtcctggcc gcccagggtg aggtcctcgg cggcgatacg gctctccagc cgcaccggcg
     8641 gcgcgaagcg cagtgcctcc tccacggcgc cggccgcgag ttcagggttc tcgccgagcc
     8701 gcgcccactg cacgggacgg gtgagcagcg actccagggt gttgttgatg agcccggcgg
     8761 tgacctcgac gccgaccacg gcggtcagca cacccacggc gagcgcgtcc tgcccggcgg
     8821 aggcggcgga ggagccggcg tgcagcaccg cgctgagcag gtcgtcaccc ggctgcgtcc
     8881 gccgcgcctc gacgaggtcg ccgacgaggg cccgtacgtc ctcgacggcc tcggtgagcc
     8941 ggcgggtcac ggcgagcggc tgggggcaga gcgcggcgtc gagggcgaca ccgagggcga
     9001 ggcacgtcgc cgcgaagcgt tcccgctggg cggcggggac accgagcagc tccgcggcgg
     9061 cctccgtggc caccgggcgg gagtagtccg ccatgaggtc gaagctgtcc ccggtacggt
     9121 cggcggcctc ccggtgcacg cgcccggcgt gctcgcggac accctccgcc ggggcgccgc
     9181 ccgcactgcc caggacggcg gaggcggacc gcgcccagcg cgtgtggtcg gcgtccgacg
     9241 cgtggaggaa ggcccggtcc agcgggatga tgtggcacag ctgcggattg ctccaggcgt
     9301 cggagaagac gtgccgctgc gggcccggca ggtcggcgtg gcgcagggcg agccggggat
     9361 cggccagggc ctcggcggcg acgccgtgcc ggccggtgac ccaggcgccg gtggtgctct
     9421 gccacagcgg cgtcccggct tcccgtatcc ggcgggtcag cagcgcgggg tcgtcgctct
     9481 cggcgcgcag ggtcagggcg tacgggtcgc cgctggtgcc gtagatccag tggaagccgc
     9541 gggcggtcag gagatgacgg cccagttcgc tgtcggtctg ctggttctcc gccgtctccg
     9601 gcgcgttctg tgtctgcacg gcagtctcct tcgggacgtg gttcaggtga gggacagacc
     9661 gccgtcgacc gcgagcaccg ctccggtcgc gtaagcggcg cgcgggtcgg ccagctggac
     9721 ggcccaccag gcgatgtcct cgggccggcc gacccggccg gccgggacgc gggcggcgat
     9781 ctgcccgagg aagcccgcgt aggcctcccg tgacatgccc gagcgttcac cgatgccggt
     9841 gtcgatcacg ccgggcgcca ggccgaggac acggatgccg cggggtgcca gttcgacggc
     9901 ccaggtccgg gtgaggaagt cgagcccggc cttggcggcg ccgtagacac cgttctgcgg
     9961 ccaggcccgg cggcccagag ctccggccga gccgatgttc agcacggttc ccccgccgtc
    10021 ggccgacagg gcgtccaggg tctgccgggt gagcagcagc ggggccagga ggttgctgtc
    10081 gaactgctcg cgggcggcct ccggctcggt ctccgccagg ccggcgaacc caccggtggc
    10141 cgcgttgttc acgaggacgt cgatacggcc caacgcgtcc agcgccgcgt cggtgatggc
    10201 gcgcggaccg tccggatcgg tgagatcggc ggtcaggaca ctgatgccgg ggtggccctc
    10261 ggcggtcccg gccagggtcg cggcggtgcg gcctacgacg agtacccggt cgccgcggtc
    10321 ggcgaaggcg tgggccgtgg cccgcccgat cccggtcccg ccgccggtga cgatcacgcc
    10381 ccgcggcgct gtcggttctg ctatggcgct catgccccgg accgtaggcc gggccgctcg
    10441 attcacggtc gactcccgct cggccgcggc ctcagggccg gtcgtcacgg gtcaccacgc
    10501 gttcccggac caggagccgg ccgccctccc ggaccaggac gtcccggcag gtgcagacca
    10561 ggtgcagccg ggcggggccg ccctgcgcga cggcgacgat cgagaccagg ctctcggcgg
    10621 tcagcgagcc gtcgtccgcg ggggtgacgg tgagcatgcc gacccagtgg cggtgcgtct
    10681 cgcgggcggc ggccagaccc gccgcggcgt tgcgggcacc ctcggcgagc agcgggcgtc
    10741 cgcgtaccgg ctccgggagc gagggcggtg cgaaggagcc gtcctcggtg aaggtgccgg
    10801 cccaggtctc ggcctcgccc gagtccaggt accgcatctg ccgtgcgtag aaatgctgta
    10861 cctcggcgta gacgtccgcc ggggccgtcg gtgcctgtgc tgtcatgccg tgtcaccttt
    10921 cgccgttccc gcgtcgggga cgggtgcgtg cccgggtccc cggtgagtgt cacgacggtc
    10981 gcagcgcgac tccaggatcg gtcgagcggg gggcgggcgg atgcgctggc ggctgttcag
    11041 tcagcctcca acgcttctca agccgcgctg gtgagcatgg gctggctcgc aggaacccat
    11101 cgccgggagg cgcgtgtgcg catcatcgac ctgtcctcac ccgtggacgc ggcgggtttt
    11161 gaacctgatc ccgtcgtgca cgacgttctc ggtccgaagg aggccgccac gcacatgagc
    11221 gaggagatgc gtgagcactt cggcatcgac ttcgatccgg cggaactgcc ggagggcgaa
    11281 ttcctctcgc tcgaccgtct ccagctgacc acccacaccg gaacccatgt cgacgcgccc
    11341 tcgcactacg gcacgcgcgc cgcgtaccgg gacggtccgc cgcggcacat cgacgagatg
    11401 ccgctcgact ggttcttccg gcccgccgtc gtcctcgacc tcagcgacca gggcacgggc
    11461 gcggtcggcg ccgacgtgct gcggcgggag atggaccgga tcggccacac tccctcgccc
    11521 atggacatcg tcctgctcag gaccggtgcc gacgcgtggg cgggaacccc gaagtacttc
    11581 acggacttca ccgggctgga cggttcggcc gtgcacctgc tgctggacct gggggtgcgg
    11641 gtgatcggca cggacgcgtt cagcctggac gcgccgttcg gcgacatcat cacccgctac
    11701 cgggccacgg gcgacccgtc ggtcctgtgg cccgcccatg tcatcgggcg ggaccgggag
    11761 tactgccagg tcgagcggct cgccgggctc gaccggctgc ccgccgcgca cgggttccgg
    11821 gtcgcgtgct tcccggtgcg gatcgccgga gcgggcgccg gctggacgag ggcggtggcc
    11881 ctggtcgacg agtgaggagc gcacggcggg ccgagcggac gacgcgccca ccggggcgcc
    11941 gacggaggga acagacatgt acggccggga actcgcggac gtgtacgagg ccatctaccg
    12001 cagccgcggc aaggactggg gacaggaggc ggcggacgtc tcgcggatca tcaccgaacg
    12061 gcgtccggga gccggctcgc tgctcgacgt cgcctgtggc acgggcgccc atctgagcgt
    12121 gttcagcacg ctgttcgagg tcgccgaggg cctggagatc gcggagccga tgcggcggct
    12181 cgccgagcag cggctgcccg gcaccaccgt gcacgccggc gacatgcgcg acttccggct
    12241 cccgcgcacc tacgacgcgg tgagctgcat gttctgcgcc atcggctatc tggagacgct
    12301 ggacgacatg cgggccgccg tccggtcgat ggccgctcat ctggagcccg gcggcgtgct
    12361 ggtcgtcgaa ccctggtggt tccccgagaa cttcatcgag ggctatgtcg cgggtgacct
    12421 ggcccgcgag gagcaccgga ccatcgcccg gatctcgcac accacccgga agggccgggc
    12481 cacccgcatg gaggttcgct tcaccgtggg ggacgccgcc ggcatccagc agttcacgga
    12541 gatcgacgtg ctgaccctgt tcaccaggga cgaatacacc gccgcgttca ccgacgccgg
    12601 ctgttccgtt gaattcctgg aggacggacc caccggccgc ggtcttttcg tcggtgttcg
    12661 cgaacagcgc tgagccggag gaaggtcagc ccgagaattc tcgggcgacc gccatcacat
    12721 agcgaccgta accggactgc gacatctgct caccgagtcg gtggcacatg tccgcgtcga
    12781 tgaatcccat gcgcagcgcc acttcttcga cgcaggcgat gcgcacgccc tgccgttctt
    12841 cgagcgtgcg cacgtactgg gtggcctgaa gcagcgattc cggggttccg gcgtcgagcc
    12901 aggcgaaacc gcggccgaga tcgaccagac gcgctcggcc gcgggccagg taattccggt
    12961 tcacatcggt gatctccagt tcgccgcgcg gcgagggccg gaggttcttc gcgatgtcca
    13021 ccacttcgtt gtcgtacaga tagagcccgg tgatggcgag gtcggaacgc ggccggagcg
    13081 gcttctcctc cagggagacg agttgccccg acgcgtcggt ctcgcccacg ccgtagcgct
    13141 ccgggtcctc cacggggtag ccgaacagca cgcagccctg gacgtcgtgg acgttgctct
    13201 ggagcaggtc gtagaagtgg tgtccgtgga agatgttgtc cccgaggacc agtgccacgt
    13261 cgtcgtcacc cacgtggtcg gcgccgatga cgaaggcgtc ggccagtccg gccggccggt
    13321 tctgcaccgc gtagtcgatg cgcaggccga gctgggagcc gtcgcccagg agccggcgga
    13381 actgttccag atcgcgctcg gtgcagatga gcaggatctc cctgatgtcc gccagcatca
    13441 gcaccgagag cggatagtag atcatcggct tgtcgccgac cggaagaagc tgttttgata
    13501 cggagacggt tatcggatgg agccgtgttc ccgaaccgcc ggcgagaata atccccttca
    13561 tgggtatgcc cctgtcctcg atttcttctc atgctaacga ccggattcgc tcggcagcaa
    13621 gccggaaaat ttctggtcca gggaaaatcg agcggtaata gagggaattt cggggttgtg
    13681 gaccggagcg agaatgtgat gtgctgcgag gggatggtga cgccctgtgg cacggcatcg
    13741 gcgtggcatc ggcaaggcat cggcaagggg aggaaaagaa ttaatgacga ctctcgtctg
    13801 ggactaccta caggaatacg agaacgaacg cgccgacatt ctggacgccg tggagacggt
    13861 cttcagctcg ggtcggctcg tcctcggtga cagcgttcgc ggattcgagg aggagttcgc
    13921 cgcgtaccac ggcgcggcgc actgcgtcgg tgtcgacaac ggcaccaacg cgatcaagct
    13981 ggccctccag gcgctcggcg tcggccccgg tgacgaggtc gtcacggtgt ccaacaccgc
    14041 ggcccccacg gtcgtggcca tcgattcggt gggcgccacc ccggtgttcg tcgacgtcca
    14101 cccggacagc tacctcatgg acaccgagca ggtggaggcc gcactcacgc cccggacccg
    14161 atgcctgctg ccggtccatc tctacgggca gtgcgtcgac ctggctccgc tggagcggct
    14221 cgccgcggag cacgacctgt tcctcgtcga ggactgcgca caggcccacg gtgcccgccg
    14281 cgccggccgg ctcgccggca ccaccggcga cgccgccgcc ttctccttct accccacgaa
    14341 ggtgctcggc gcctacggcg acggaggcgc cgtggtgacc tcccgggacg acacccaccg
    14401 cgcgctgcgc cgactgcgct actacggcat ggaggagcgg tactacgtcg tcggcacccc
    14461 gggtcacaac gcccggctcg acgaggtcca ggccgagatc ctgcggcgca agctgcgccg
    14521 gctcgacacc tacatcgagg ggcggcgggc cgtcgcccgg cgctacgagg acgggctcgg
    14581 cgacaccggc ctggtgctcc cgcacaccgt ccccggcaac gagcacgtgt actacgtcta
    14641 cacggtgcgc cacccgcggc gcgacgacat catcaaggcc ctcaaggcgt acgacatcga
    14701 gctgaacatc agctatccct ggcccgtgca caccatgtcc gggttcgccc acctcggcta
    14761 cggcaagggc tcgctgcccg tcaccgagga cctggccggc cagatct
//
