BGC0000197: aranciamycin biosynthetic gene cluster from Streptomyces echinatus
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Location: 1 - 35,936 nt. (total: 35,936 nt).
This entry is originally from NCBI GenBank DQ915964.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000197
Short description aranciamycin biosynthetic gene cluster from Streptomyces echinatus
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Type II)
  • saccharide (hybrid/tailoring)
Loci
DQ915964.1
via Heterologous expression
Compounds
  • aranciamycin
Species Streptomyces echinatus [taxonomy]
References
Chemical products information
aranciamycin Evidence:
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C27H28O12
Chemical database entries
NPAtlas
PubCHEM
ChEMBL
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ABL09949.1
 711 - 1541 (-) SCC75A.25c
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    • ABL09950.1
    		 2069 - 2680 (-) hypothetical protein
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      • ABL09951.1
      		 3617 - 5569 (+) oxidoreductase
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        • ABL09952.1
        		 6024 - 8852 (-) response regulator
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          • ABL09953.1
          		 9913 - 11256 (-) oxidoreductase
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            • ABL09954.1
            		 11272 - 12216 (-) cyclase
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              • ABL09955.1
              		 12254 - 13039 (-) ketoreductase
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                • ABL09956.1
                		 13224 - 13679 (+) aromatase
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                  • ABL09957.1
                  		 13854 - 14120 (-) acyl carrier protein
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                    • ABL09958.1
                    		 14144 - 15370 (-) chain length factor
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                      • ABL09959.1
                      		 15367 - 16638 (-) ketoacyl synthase
                      • Scaffold biosynthesis
                      • Knock-out
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                      • ABL09960.1
                      		 16844 - 17617 (-) cyclase
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                        • ABL09961.1
                        		 18199 - 18807 (+) regulator
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                          • ABL09962.1
                          		 18737 - 19957 (-) signal transduction histidine kinase
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                            • ABL09963.1
                            		 20708 - 21517 (+) pathway specific transcription activator
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                              • ABL09964.1
                              		 21990 - 22646 (-) unknown
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                                • ABL09965.1
                                		 22835 - 25870 (-) helicase
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                                  • ABL09966.1
                                  		 26090 - 27349 (-) O-methyltransferase
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                                    • ABL09967.1
                                    		 27737 - 29260 (+) transmembrane efflux protein
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                                      • ABL09968.1
                                      		 29585 - 30868 (+) L-rhamnosyltransferase
                                      • Tailoring
                                      • Activity assay
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                                      • ABL09969.1
                                      		 31341 - 32867 (-) oxidoreductase
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                                        • ABL09970.1
                                        		 33305 - 34192 (+) oxidoreductase
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                                          • ABL09971.1
                                          		 34703 - 35758 (+) methyltransferase
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                                            Biosynthesis information
                                            Annotation changelog

                                            Entry version: 4

                                            Date
                                            Changes
                                            Submitters
                                            Reviewers
                                            2022-10-07
                                            Update chemical activity to schema version 2.11
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                            Entry version: 3

                                            Date
                                            Changes
                                            Submitters
                                            Reviewers
                                            2022-09-15
                                            Removed gene names of 'No gene ID'
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                            Entry version: 2

                                            Date
                                            Changes
                                            Submitters
                                            Reviewers
                                            2019-10-16
                                            Migrated from v1.4
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                            2019-10-16
                                            Updated compound(s) information (NPAtlas curation)
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                            Entry version: 1

                                            Date
                                            Changes
                                            Submitters
                                            Reviewers
                                            2015-06-12
                                            Submitted
                                            • (ID: LPHAMZXQ3BT6INJWOLKUYGWU)
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                            Detailed domain annotation
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