BGC0000198 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0000198 (Salinispora arenicola CNB527)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 1	T2PKS	1	69,752	High	arenimycin A	PKS:Type II+saccharide:hybrid/tailoring

BGC0000198 - Region 1 - T2PKS

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Location: 1 - 69,752 nt. (total: 69,752 nt) Show pHMM detection rules used

Region on contig edge.

T2PKS: (t2ks and t2clf)

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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Gene overview

MIBiG

Tailoring

MIBiG comparison

KnownClusterBlast

NRPS/PKS domains

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 69,753
Label		BGC0000198

Tailoring functions

Oxidoreductases: dehydrogenase oxidoreductase oxygenase

B033_RS0101545: cytochrome P450

smcogs: SMCOG1007: cytochrome P450

B033_RS0101585: aldo/keto reductase family oxidoreductase

smcogs: SMCOG1039: aldo/keto reductase family oxidoreductase

B033_RS0101655: cytochrome P450

smcogs: SMCOG1007: cytochrome P450

B033_RS0101670: short-chain dehydrogenase/reductase SDR

smcogs: SMCOG1001: short-chain dehydrogenase/reductase SDR

B033_RS28005: cytochrome P450

smcogs: SMCOG1007: cytochrome P450

B033_RS28015: monooxygenase FAD-binding

smcogs: SMCOG1050: monooxygenase FAD-binding

B033_RS28045: oxidoreductase

smcogs: SMCOG1079: oxidoreductase

Transferases: aminotransferase glycosyltransferase methyltransferase transferase

B033_RS0101505: glucose-1-phosphate adenylyl/thymidylyltransferase

smcogs: SMCOG1064: glucose-1-phosphate adenylyl/thymidylyltransferase

B033_RS0101530: methyltransferase

smcogs: SMCOG1248: methyltransferase

B033_RS0101535: DegT/DnrJ/EryC1/StrS aminotransferase

smcogs: SMCOG1056: DegT/DnrJ/EryC1/StrS aminotransferase

B033_RS0101555: glycosyltransferase, MGT family

smcogs: SMCOG1062: glycosyltransferase, MGT family

B033_RS0101640: methyltransferase

smcogs: SMCOG1089: methyltransferase

B033_RS27990: DegT/DnrJ/EryC1/StrS aminotransferase

smcogs: SMCOG1056: DegT/DnrJ/EryC1/StrS aminotransferase

B033_RS28010: glycosyltransferase, MGT family

smcogs: SMCOG1062: glycosyltransferase, MGT family

B033_RS32390: O-methyltransferase

smcogs: SMCOG1042: O-methyltransferase

Hydrolases: deacetylase

B033_RS28000: acetylornithine deacetylase

smcogs: SMCOG1247: acetylornithine deacetylase

Lyases: cyclase dehydratase

B033_RS0101615: cyclase/dehydrase

smcogs: SMCOG1128: cyclase/dehydrase

B033_RS0101700: NAD-dependent epimerase/dehydratase

smcogs: SMCOG1010: NAD-dependent epimerase/dehydratase

B033_RS28025: Polyketide synthesis cyclase

smcogs: SMCOG1225: Polyketide synthesis cyclase

B033_RS28050: NAD-dependent epimerase/dehydratase

smcogs: SMCOG1010: NAD-dependent epimerase/dehydratase

Ligases: synthase

B033_RS0101660: Beta-ketoacyl synthase

smcogs: SMCOG1022: Beta-ketoacyl synthase

B033_RS0101665: Beta-ketoacyl synthase

smcogs: SMCOG1093: Beta-ketoacyl synthase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000198.5	1.00	PKS, saccharide	arenimycin A	Salinispora arenicola CNB527
BGC0000231.5	0.66	PKS	griseusin A, griseusin B	Streptomyces griseus
BGC0000234.5	0.61	PKS	jadomycin	Streptomyces venezuelae ATCC 10712
BGC0001275.3	0.59	PKS	6-methylsalicyclic acid	Glarea lozoyensis
BGC0001197.5	0.59	PKS	frankiamicin	Frankia sp. EAN1pec
BGC0000278.3	0.58	PKS	urdamycin	Streptomyces fradiae
BGC0000272.3	0.58	PKS	spore pigment	Streptomyces collinus
BGC0001723.5	0.57	PKS	oviedomycin	Streptomyces antibioticus
BGC0002000.4	0.56	PKS	setomimycin	Streptomyces aurantiacus JA 4570
BGC0002514.3	0.55	PKS	julichrome Q6.6	Streptomyces sampsonii

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000198.5	1.00	PKS, saccharide	arenimycin A	Salinispora arenicola CNB527
BGC0000231.5	0.66	PKS	griseusin A, griseusin B	Streptomyces griseus
BGC0000234.5	0.61	PKS	jadomycin	Streptomyces venezuelae ATCC 10712
BGC0001275.3	0.59	PKS	6-methylsalicyclic acid	Glarea lozoyensis
BGC0001197.5	0.59	PKS	frankiamicin	Frankia sp. EAN1pec
BGC0000278.3	0.58	PKS	urdamycin	Streptomyces fradiae
BGC0000272.3	0.58	PKS	spore pigment	Streptomyces collinus
BGC0001723.5	0.57	PKS	oviedomycin	Streptomyces antibioticus
BGC0002000.4	0.56	PKS	setomimycin	Streptomyces aurantiacus JA 4570
BGC0002514.3	0.55	PKS	julichrome Q6.6	Streptomyces sampsonii

Similar known clusters from MIBiG 4.0

Detailed domain annotation

Selected features only

Show module domains

Type II PKS

Type II PKS gene cluster prediction details

Cluster section:: 0 to 69752
Starter unit(s):: acetyl-CoA (Score: 0.0; E-value: 0)
Malonyl elongations:: 11|12 (Score: 685.5; E-value: 4.5e-209)
Product class(es):: pentangular polyphenol
Product molecular weight(s):: acetyl-CoA_11: 866 Da
acetyl-CoA_12: 908 Da

B033_RS0101555: GT (Score: 429.2; E-value: 4.6e-131)
B033_RS0101585: KR (Score: 44.6; E-value: 3.2e-14)
B033_RS0101610: CYC C5-C18 (Score: 182.7; E-value: 5.7e-57)
B033_RS0101615: CYC C9-C14 (Score: 260.5; E-value: 9e-81)
B033_RS0101640: MET carboxy_O (Score: 342.1; E-value: 3.9e-105)
B033_RS0101660: KS (Score: 734.3; E-value: 8.4e-224)
B033_RS0101665: CLF 11|12 (Score: 685.5; E-value: 4.5e-209)
B033_RS0101670: KR C19 (Score: 396.7; E-value: 9.4e-122)
B033_RS0101685: ACP (Score: 103.0; E-value: 1.5e-32)
B033_RS27995: MET C18O (Score: 347.6; E-value: 2e-106)
B033_RS28010: GT (Score: 394.0; E-value: 2.2e-120)
B033_RS28015: OXY (Score: 291.4; E-value: 3.3e-89)
B033_RS28025: CYC C4-C21/C2-C23|C2-C19 (Score: 152.5; E-value: 7.6e-48)
B033_RS32390: MET C13O|C17O (Score: 409.6; E-value: 1.8e-125)