LOCUS       BGC0000200             31965 bp    DNA     linear   ENV 15-JUL-2015
DEFINITION  Uncultured bacterium arixanthomycin gene cluster, complete sequence.
ACCESSION   BGC0000200
VERSION     BGC0000200
KEYWORDS    ENV.
SOURCE      uncultured bacterium
  ORGANISM  uncultured bacterium
            Bacteria; environmental samples.
REFERENCE   1  (bases 1 to 31965)
  AUTHORS   Kang,H.S. and Brady,S.F.
  TITLE     Arixanthomycins A-C: Phylogeny-guided discovery of biologically
            active eDNA-derived pentangular polyphenols
  JOURNAL   ACS Chem. Biol. 9 (6), 1267-1272 (2014)
   PUBMED   24730509
REFERENCE   2  (bases 1 to 31965)
  AUTHORS   Kang,H.-S. and Brady,S.F.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-DEC-2013) Laboratory of Genetically Encoded Small
            Molecules, The Rockefeller University, 1230 York Avenue, New York,
            NY 10065, USA
COMMENT     ##Assembly-Data-START##
            Assembly Method       :: Newbler v. 2.6
            Sequencing Technology :: IonTorrent
            ##Assembly-Data-END##
            ##antiSMASH-Data-START##
            Version               :: False
            Run date              :: 2025-08-15 16:39:36
            NOTE :: This is a single region extracted from a larger record!
            Orig. start           :: 0
            Orig. end             :: 31965
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     region          1..31965
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T2PKS"
                     /region_number="1"
                     /rules="(t2ks and t2clf)"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(1..1059)
                     /locus_tag="arx1"
     CDS             complement(1..1059)
                     /NRPS_PKS="Domain: NAD_binding_4 (4-252). E-value: 1e-11.
                     Score: 36.3. Matches aSDomain:
                     nrpspksdomains_arx1_NAD_binding_4.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="arx1"
                     /note="arx1"
                     /product="NAD-dependent epimerase/dehydratase"
                     /protein_id="AHX24686.1"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 8e-11, bitscore:
                     32.7, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRILVTGGAGFIGSQVVRQLLDAGHDIRVLDALIPDVYRGRAPAE
                     LPAEVDFVHGDLRDRATVAQALCGIDLVSHQAAMVGRGREILDVVQYVDCNDLGTANLL
                     AEMISAGVDRMVLASSVVIYGDSRYSCDVHGFVRPPRRSREDLDAGRFEPRCPTCGADL
                     VASAAEEDDELNPPRNVYAVTKLAQELLVSCWARETGASVTALRYHNVYGPLMPYESPY
                     SGVASVFRSAVARGEAPRVFEDGGPKRDFVHIRDVAGANVAALARTDPGFRAYTVASGQ
                     PRSIGELAATLADAASAPPPVVTGQYRIGDVRHVFATPRRLIDELGWRPTVDFEAGMKE
                     FATAPMSQGQPD"
     source          1..31965
                     /clone="BAC-AZ1076/33/378"
                     /country="USA: Arizona"
                     /db_xref="taxon:77133"
                     /environmental_sample=""
                     /isolation_source="desert soil"
                     /mol_type="genomic DNA"
                     /organism="uncultured bacterium"
     misc_feature    1..31965
                     /note="arixanthomycin gene cluster"
     subregion       1..31965
                     /aStool="mibig"
                     /contig_edge="True"
                     /label="PKS, saccharide"
                     /subregion_number="1"
                     /tool="antismash"
     cand_cluster    1..31965
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(t2ks and t2clf)"
                     /kind="single"
                     /product="T2PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..31965
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[15999:18510](+)"
                     /cutoff="20000"
                     /detection_rule="(t2ks and t2clf)"
                     /neighbourhood="35000"
                     /product="T2PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      16000..18510
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(t2ks and t2clf)"
                     /neighbourhood="35000"
                     /product="T2PKS"
                     /protocluster_number="1"
     aSDomain        complement(304..1047)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_arx1_NAD_binding_4.1"
                     /evalue="1.00E-11"
                     /label="arx1_NAD_binding_4.1"
                     /locus_tag="arx1"
                     /protein_end="252"
                     /protein_start="4"
                     /score="36.3"
                     /tool="antismash"
                     /translation="VTGGAGFIGSQVVRQLLDAGHDIRVLDALIPDVYRGRAPAELPAE
                     VDFVHGDLRDRATVAQALCGIDLVSHQAAMVGRGREILDVVQYVDCNDLGTANLLAEMI
                     SAGVDRMVLASSVVIYGDSRYSCDVHGFVRPPRRSREDLDAGRFEPRCPTCGADLVASA
                     AEEDDELNPPRNVYAVTKLAQELLVSCWARETGASVTALRYHNVYGPLMPYESPYSGVA
                     SVFRSAVARGEAPRVFEDGGPKRDFV"
     CDS_motif       complement(988..1050)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arx1_0001"
                     /evalue="1.20E-03"
                     /label="PKSI-KR_m1"
                     /locus_tag="arx1"
                     /protein_end="24"
                     /protein_start="3"
                     /score="11.5"
                     /tool="antismash"
                     /translation="LVTGGAGFIGSQVVRQLLDAG"
     gene            complement(1062..1796)
                     /locus_tag="arx2"
     CDS             complement(1062..1796)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="arx2"
                     /note="arx2"
                     /product="hypothetical protein"
                     /protein_id="AHX24687.1"
                     /transl_table=11
                     /translation="MIAELLAQSGNKILRNIAPDGRDYWAARFWDRESAEQHPTLRGDF
                     LDQKEVIGRYLRTYAVDVDSSLEVACGTGEFTAMTAELTHVRHMTAIDISAQGLARAAR
                     RVDHDDLELVQGDFWQHELPTADLVMCIDAIHHLGDIREVLTRLRSFIAPGGLFIGNVW
                     TSDNFHEFERRRYGRIEHLRRTLAFLGTAAIIRVSGGKLRTGAYRTQLRPSDESTAIVR
                     SLFREVLAVDEHRYFTAFAARG"
     gene            complement(1822..2988)
                     /locus_tag="arx3"
     CDS             complement(1822..2988)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MGT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1062: glycosyltransferase, MGT family"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="arx3"
                     /note="arx3"
                     /product="glycosyltransferase"
                     /protein_id="AHX24688.1"
                     /sec_met_domain="MGT (E-value: 1.4e-126, bitscore: 414.0,
                     seeds: 193, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVLFVTWAWPTHLFPMVPLAWALRAHGHDVRVASQPALTDAIPH
                     TGLPAVSVGKDVNVIGKLRQIAAAPAVAGRPTAGSTPRAAAMFAELAEAMLPDLVAFGR
                     RWRPDLVVFEPTAYAGPIAAAAFGVPAVRYLYGPDIMAAPVFRDAERQFLAPLWERYGL
                     DAVDTAGALTLDPCPVALQVEEPLGPRQPVQYVPYNGFGGGLPPEWSSGKATRPRVCVT
                     WGTTYGRLDPAYFLLPEVLTALSTLDIEVVAAITTAQRELCTELPAGVHVTESVPLYRL
                     LPACDAVVSHGGVGTSMTSLACAGLPLLMTPQLPDHRFHAARVAAAGAGRVLPLADFSP
                     ATIRGEVGALLDQLSYRTEAIQLRKEMLAQPTPAELVPVLVELATSAR"
     gene            3207..3887
                     /locus_tag="arx4"
     CDS             3207..3887
                     /NRPS_PKS="Domain: PKS_KR (4-140). E-value: 5.9e-10. Score:
                     31.3. Matches aSDomain: nrpspksdomains_arx4_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="arx4"
                     /note="arx4"
                     /product="short-chain dehydrogenase/reductase SDR"
                     /protein_id="AHX24689.1"
                     /transl_table=11
                     /translation="MTVRTALVTGANRGLGRAVASCLRKRGYRVVVAARDVGEAGAVAA
                     ELGVGVTPAALDVTDPRAVARLAADLSVVDIVVNNAGVLETSGASPASVDLSMVEHEIR
                     VNTLGSWRVAQAFLPGMVARRWGRVVMVSSGTSTFTHGLFGGTPGYTVSKVGLNAVTAL
                     LAAETAGTGVLVNAVNPGLVRTRMRPDAERLPEEAAEDIAWVATAPNGSPSGVLFSRRK
                     IIGW"
     aSDomain        3219..3626
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_arx4_PKS_KR.1"
                     /evalue="5.90E-10"
                     /label="arx4_PKS_KR.1"
                     /locus_tag="arx4"
                     /protein_end="140"
                     /protein_start="4"
                     /score="31.3"
                     /tool="antismash"
                     /translation="TALVTGANRGLGRAVASCLRKRGYRVVVAARDVGEAGAVAAELGV
                     GVTPAALDVTDPRAVARLAADLSVVDIVVNNAGVLETSGASPASVDLSMVEHEIRVNTL
                     GSWRVAQAFLPGMVARRWGRVVMVSSGTSTFT"
     CDS_motif       3225..3293
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arx4_0001"
                     /evalue="6.70E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="arx4"
                     /protein_end="29"
                     /protein_start="6"
                     /score="12.4"
                     /tool="antismash"
                     /translation="LVTGANRGLGRAVASCLRKRGYR"
     gene            3911..5761
                     /locus_tag="arx5"
     CDS             3911..5761
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="arx5"
                     /note="arx5"
                     /product="amidotransferase"
                     /protein_id="AHX24690.1"
                     /sec_met_domain="GATase_7 (E-value: 2.3e-33, bitscore:
                     106.0, seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 4e-73, bitscore:
                     238.2, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGIVGWIDYRRDLSRAAPVVRAMAATMAARGPDGEGVWTSRHAA
                     LGHRRLEVSGYDHVDQPFVFEVDGQVVATAVFSGNLDNLAELRTVLASTGRRLRDGGEA
                     EIVLHGYLEWGRDCVSRMAGVFAFAVWDARARELFLGRDRLGLKPLYYYELPHGILFAS
                     EQKALIAHPLVTPELDREGLAELLTYAGTPDHGVLRGFRKLRGGHVAVVRESGVSRSRY
                     WQLSAYHHDTDLAATVERTRELLLDAVRAQSRAAAPTGFLLSGGLDSSVVVGLAAKAGA
                     GTPLRTYTVTFAGYDEQFRPDFVRGTPDGPYVRALVEFVGAEHRDIVLATADLLDPVAR
                     TSALRAKDLPSMLGDMNTSLYLLCLAAGDHVKVALSGETADSVFGGNVYGAEETGGTAG
                     RTFPWVRFHEKHAGHHAMGGGLFSRDLLARLDLVEYGADRCQESFAETPQPDDVDPVER
                     RARQDTYLQLTRWADSQLAHSERNAMAAGLDVRMPFADHRLVDYVFNVPWQLKSFDGKG
                     KSLLRAAAEGIVPDTVLNRPKSPFPVSIDPAYQRVLHEELSRVANDPASPAAPLLELAT
                     VRERLATPEALAGSWVARTDVEMVLAFDQWLREYGVRLTC"
     gene            5791..6855
                     /locus_tag="arx6"
     CDS             5791..6855
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042: O-methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="arx6"
                     /note="arx6"
                     /product="O-methyltransferase"
                     /protein_id="AHX24691.1"
                     /transl_table=11
                     /translation="MPHEETFWEWMDGHEEWPPFDRLLFLVYGPKIMGVLRALAELGVA
                     DELKDGPLTIAELADRTGAQEQPLFRLLRTAAALRVFRQGSDGRFGLTPEAEPLRSDLD
                     SSLRDLVRFSGDPLLTAPYANLALSVRTGKPAFDQVYGASFYDHVEAVPEDAVLFDRTM
                     TQRSWLTAVTLLRRVDLSRFSRIADLGGGQGHFLGEALTKHYQDATALLFERPTVLARA
                     KPLLAEYGVTDRVSLEAGDFFSEVPVGYDAYILNAVLNGLDDEQSKQVLARVRDAIGTD
                     TEARLFIFEKVMTESVNAWDYSKLLDMDMLVLFGGRERTLSDWRELTEAAGFELLTTPE
                     RGGSPWSALECRAR"
     gene            complement(6917..7744)
                     /locus_tag="arx7"
     CDS             complement(6917..7744)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /locus_tag="arx7"
                     /note="arx7"
                     /product="ABC transporter"
                     /protein_id="AHX24692.1"
                     /transl_table=11
                     /translation="MTAQIQARPAGGPGAVVLDCLLLTQRNLRNTMRIPQALFFTMLQP
                     IMFVLLFSYVFGEAIPLPDHGNYREYVMIGIFVQTFAFGGMTTGANLADDLRKGLIDRF
                     RSIPMTQPAVLVGRTVSDIFRNAVTLVLMALFALLVGWRTHTDFGGFVAGFGLLLFFAF
                     AMSWAGTLLGLAVSEPGAVISGGLAAVFPVVWLSNAFVPIEGMAPWMQAVASWNPVSSV
                     VVAVRELLGNPNPIGADPALPLRHPVAAGLLWTSVLLLVCVPVAARAYQHKVS"
     gene            complement(7741..8697)
                     /locus_tag="arx8"
     CDS             complement(7741..8697)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /locus_tag="arx8"
                     /note="arx8"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="AHX24693.1"
                     /transl_table=11
                     /translation="MTAVIECAGLVKRYGEVVALDDVGLWVEEGSVLGLLGPNGAGKTT
                     TVRVLSTLLRPDEGWARVGGYDVLRQPQQVRRLLGLSGQYAAVDQYLTGRENLVLFGRL
                     HRLRRQAALRRADELIDRFDLGEAAGRLVRTYSGGMRRRLDLAASLIARPRVIAMDEPT
                     TGLDPRSRLTTWELVGELVEQGTTVLLTTQYLEEADRIADRIVVVDAGRVIADDTAAEL
                     KRRTGGDRIELTLADRSGQGAASAVLAAIGDGDPVVDDRRLSVPVSTGMRALATVAGAL
                     AERGLAVADLGLRQPTLDDVFLTITGHRAPVPEEVPA"
     gene            complement(8694..9872)
                     /locus_tag="arx9"
     CDS             complement(8694..9872)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MGT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1062: glycosyltransferase, MGT family"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="arx9"
                     /note="arx9"
                     /product="glycosyltransferase"
                     /protein_id="AHX24694.1"
                     /sec_met_domain="MGT (E-value: 1.2e-128, bitscore: 420.8,
                     seeds: 193, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVLFATWGWPSHYYPLATLGWACRSAGHEVRVASQPALMDTVVH
                     SGLTAVRVGKDVDFGELFGRMMGPLVAVPDDPVAQQERVRALGVVPFRMFAEVAAAMAG
                     DLIEYCRLWRPDVIIYEPTSYAALLAASAIGVPAVRHVWSADYPYVGRAGEAAVMPELF
                     ARFGVPEVDTLGALTVDACPPSMQVEVDYPREVIRYVPYNGQAEAPDWLLEPPQARRVC
                     LTWGTTVSRLHEGMFGLPELVDSVRGLPDVELVLAVTSQQRGLLGPLAPNVRVLENLPL
                     HLVLPTCSAQVMQGGAGTIMTALSAGVPQLGVPQIPDQLFNCRRLAETGAGSYIPRREA
                     TADDLRRLLTELLEDPAHAAAARRVAAEIAAQPAPSAVVPALERLAAKGPRS"
     gene            complement(9874..11460)
                     /locus_tag="arx10"
     CDS             complement(9874..11460)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050: monooxygenase FAD-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="arx10"
                     /note="arx10"
                     /product="FAD-binding monooxygenase"
                     /protein_id="AHX24695.1"
                     /transl_table=11
                     /translation="MRTPVLIVGGSFVGLSSAVFLTTYGIRPMVIERHPGPGIHPRARG
                     LNPRTMELFRGAGVEDRIRTGTPPLTGNELLVQAESLAGKEVRRIESSTFAGLGTVSSS
                     DWVSIGQDKAEPILRDVAVERGADIRYRTELLSFTQDEDGVTAVVLDRATSTQRIVQAQ
                     YMIGADGHQSSVREALGIEVDDLAPTVHALSVLFRADLSHALRGREVTMVVALNPAARF
                     GVLTPVEGDQWMFGIRYDPDKGETPEQFTDEVWTGLVRAAVGEDDLEVTIDLRDEWEVC
                     SRIARAYQAGRVFLAGDSAHLMPPAGGFGANTGAQDAQNLAWKLAMVLHGQASPALLDT
                     YDAERRPAGELTVRQSAERTAARQNEEAGEPRLDELTVMFGYCYDSAAVLTGGRSPGPA
                     ADPRVPSGLPGTRAADIPLLRDGTRLSTMDLFGRGFVLLTTESGGEWIDAAKVYAGETG
                     IELSASTVGPAGSGADLVDVGGRLPDVYGIQGEEAVLIRPDGFVCWRGSAGEGGPAEQL
                     ATVFGRILEGQ"
     gene            complement(12253..13065)
                     /locus_tag="arx11"
     CDS             complement(12253..13065)
                     /codon_start=1
                     /locus_tag="arx11"
                     /note="arx11"
                     /product="hypothetical protein"
                     /protein_id="AHX24696.1"
                     /transl_table=11
                     /translation="MRSQAGDVLDIVLDGKHPPLPSPDPRPAGEATFRVSTPDASGHKW
                     GLVRLPAGTDLGYFLDCLNRSRSWDPAVHTRARAELNQAVDFAGGVTVYPSYGQIEHTL
                     CLEPGTYYFLDYDDLAEPDAADRIQSLRTTGPARHELKVPVDVVIEARQEGEREFYAMP
                     ERLPAECTVLLRNLSDHPQEVVFNRVHDGTTADDVRDFVLAFRTGGTPPGNVFMGAPTG
                     LMPISSGRESAMRLRFPPGRYAVCSYTSHGRTGRSGVLEEMLEIVTIG"
     gene            complement(13091..14125)
                     /locus_tag="arx12"
     CDS             complement(13091..14125)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042: O-methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="arx12"
                     /note="arx12"
                     /product="O-methyltransferase"
                     /protein_id="AHX24697.1"
                     /transl_table=11
                     /translation="MTTEWTPGTGNPAQRLVALTRGYMSSQIVGAAARLRVAEHLADGP
                     VTSAELASKISADPGATSRFLRAAASIGLVEHLGGDRFAESAMTPLLRSGRRSLVSFVL
                     SFTGPGLYRPLEQLHNVVLEGHEHTERTLGKGLWDYYKENDEESTWFADTMGEQSEFAA
                     DILIPRVNFTDTKRIVDVGGSHGVLLSRVLEAHPHTSGVLFDLPEVVERAKDYIAERGL
                     TDRVEFVPGSFLEELPAGGDLYLLKSILCDWDDDSCVRVLSNFRAAAAPGTPLVVSDWL
                     LPEKPDLFLDITNIGLLAYTNGQVRNESQYRELFRRADVDLERITTAEDNWLQVTLFEG
                     RRPE"
     gene            14331..15218
                     /locus_tag="arx13"
     CDS             14331..15218
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 2-Hacid_dh_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1100: 3-hydroxyisobutyrate dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="arx13"
                     /note="arx13"
                     /product="dehydrogenase"
                     /protein_id="AHX24698.1"
                     /sec_met_domain="2-Hacid_dh_C (E-value: 1.3e-08, bitscore:
                     25.6, seeds: 135, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGLVGLGAMGSGMAACLLRAGLPLVVHNRTAAAVRPLVDLGAHAA
                     ATAADAVGQADVVLVSLSDDDAVESVLFGAAAGALRPGTVVVNTSAISPRYARSSAERL
                     RAAGAVPVEAGVVGNPEMARAGRLRVLTGGRAEDAAAVADLLDLVGEQVVHVGDHGSAV
                     VLKLCFNLLLGAQTAVLAEAVSYGTGAGIDRDVLLDAIVQSGFSSPVLTFRASFMRSGQ
                     YEPAAFRAGLMAKDLGNVLSDATELGLGLPVVARLAERFTQLAGTWPDSDAAAVLRLQH
                     ADAGRPERTAASRP"
     gene            15240..15575
                     /locus_tag="arx14"
     CDS             15240..15575
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1225: Polyketide synthesis cyclase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="arx14"
                     /note="arx14"
                     /product="cyclase"
                     /protein_id="AHX24699.1"
                     /transl_table=11
                     /translation="MHRTLIVARLRTDDPQRIADAFGSSDETELPHLVGVSRRTLFTFH
                     DLYFHLVEADQDISPSLYRARSHPLYTDLNQRLAQLVAPYDPNWKEPKDAMASPFYVWT
                     AEKGREQ"
     gene            15572..16003
                     /locus_tag="arx15"
     CDS             15572..16003
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MannoseP_isomer"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="arx15"
                     /note="arx15"
                     /product="cyclase"
                     /protein_id="AHX24700.1"
                     /sec_met_domain="MannoseP_isomer (E-value: 5.1e-09,
                     bitscore: 27.3, seeds: 17, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTERRRLKFTTADAVPNTRRGGDLRVTLSPKTVGCTSGFGGVLWL
                     RPGEFVTEHYHPYSEEFVHVVEGSLEMTVDGERVPLAPGDSLYVPIGARHRLVNTGTEP
                     ARAVFHLSPLAPRPDLGHVDTEPPLAPAQPQPEVGGAPR"
     gene            16000..17268
                     /locus_tag="arx16"
     CDS             16000..17268
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (4-390). E-value:
                     1.1e-53. Score: 174.6. Matches aSDomain:
                     nrpspksdomains_arx16_PKS_KS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T2PKS:
                     t2ks"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) itr_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) tra_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) hyb_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) mod_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ene_KS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic"
                     /locus_tag="arx16"
                     /note="arx16"
                     /product="beta-ketoacyl synthase alpha"
                     /protein_id="AHX24701.1"
                     /sec_met_domain="t2ks (E-value: 2.5e-234, bitscore: 768.9,
                     seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 1.9e-56, bitscore:
                     182.5, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="itr_KS (E-value: 6.6e-52, bitscore: 167.8,
                     seeds: 96, tool: rule-based-clusters)"
                     /sec_met_domain="tra_KS (E-value: 7.8e-46, bitscore: 147.9,
                     seeds: 44, tool: rule-based-clusters)"
                     /sec_met_domain="hyb_KS (E-value: 2.6e-45, bitscore: 146.1,
                     seeds: 33, tool: rule-based-clusters)"
                     /sec_met_domain="mod_KS (E-value: 1.1e-41, bitscore: 134.1,
                     seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="ene_KS (E-value: 5.4e-36, bitscore: 115.2,
                     seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRSVVVTGIGVVAPGAVGREPFWALLTEGRTATRTISLFDAAAF
                     RSRVGAEVDFDPLAEGLTPRQVRRMDRAAQFAVVSMREAVRDSGVEFDRLDPGRIGVSI
                     GSAVGCTIGLEEEYQVLSDNGREWLVDHSYGVPHLYGYMVPSTLAVEVAWEVAAEGPVA
                     LISTGCTSGLDAVNHGAELIREGSADVVLAGATDAPLSPITSACFDAIKATTPNNDDAE
                     HASRPFDAHRDGFVLGEGAAVLVLEEAAAARARGARAYAELAGFASRSNAFHMTGLRPD
                     GREMAEAIRVAMDRAGVDAEDIDYVNAHGSGTRQNDLHETAAFKRSLGERAYQVPVSSI
                     KSMIGHSLGAIGSLELVACALAIERHVVPPTANLHHPDPACDLDYVPLTAREYELDAVL
                     SVGSGFGGFQSAAVLTKPRWKDV"
     aSDomain        16012..17169
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_arx16_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="1.10E-53"
                     /label="arx16_PKS_KS.1"
                     /locus_tag="arx16"
                     /protein_end="390"
                     /protein_start="4"
                     /score="174.6"
                     /tool="antismash"
                     /translation="VVVTGIGVVAPGAVGREPFWALLTEGRTATRTISLFDAAAFRSRV
                     GAEVDFDPLAEGLTPRQVRRMDRAAQFAVVSMREAVRDSGVEFDRLDPGRIGVSIGSAV
                     GCTIGLEEEYQVLSDNGREWLVDHSYGVPHLYGYMVPSTLAVEVAWEVAAEGPVALIST
                     GCTSGLDAVNHGAELIREGSADVVLAGATDAPLSPITSACFDAIKATTPNNDDAEHASR
                     PFDAHRDGFVLGEGAAVLVLEEAAAARARGARAYAELAGFASRSNAFHMTGLRPDGREM
                     AEAIRVAMDRAGVDAEDIDYVNAHGSGTRQNDLHETAAFKRSLGERAYQVPVSSIKSMI
                     GHSLGAIGSLELVACALAIERHVVPPTANLHHPDPACDLDYVPLTA"
     gene            17272..18510
                     /locus_tag="arx17"
     CDS             17272..18510
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (73-371). E-value:
                     1.4e-26. Score: 85.3. Matches aSDomain:
                     nrpspksdomains_arx17_PKS_KS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T2PKS:
                     t2clf"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) itr_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) mod_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) hyb_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) tra_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ene_KS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic"
                     /locus_tag="arx17"
                     /note="arx17"
                     /product="beta-ketoacyl synthase beta"
                     /protein_id="AHX24702.1"
                     /sec_met_domain="ketoacyl-synt (E-value: 8.6e-40, bitscore:
                     128.0, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="t2clf (E-value: 6.8e-177, bitscore: 579.3,
                     seeds: 26, tool: rule-based-clusters)"
                     /sec_met_domain="itr_KS (E-value: 2.4e-27, bitscore: 86.9,
                     seeds: 96, tool: rule-based-clusters)"
                     /sec_met_domain="mod_KS (E-value: 7.9e-24, bitscore: 75.4,
                     seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="hyb_KS (E-value: 7.1e-21, bitscore: 65.6,
                     seeds: 33, tool: rule-based-clusters)"
                     /sec_met_domain="tra_KS (E-value: 1.9e-22, bitscore: 70.8,
                     seeds: 44, tool: rule-based-clusters)"
                     /sec_met_domain="ene_KS (E-value: 4.8e-17, bitscore: 52.7,
                     seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAADPVVVTGTGVVAPTGVGTDQHWQAVLAGKSGIGRITRFDPSP
                     YPVRVGGQVPGFDAAERVPGRLIPATDHWTHMALAATDLALADAEVRPAELPEYEMAVV
                     TASSSGGTEFGQHEMERLYRRGPSWVSAYQSIAWFYAATTGQVSIRHGMRGPCGVICAE
                     QAGGLDALGQAARLVRGGEARLVVTGGTDAPLSPYGLTAQLANKRLSTSDEPAYLPFDA
                     AATGYLPGEGGAILIVEAAAAAAARGVCGYGAVLGYAAGFDPPPDSGRPPVLARTIERA
                     LATAGRAPSEVDVVFADAVGVPAEDLAEARAITEVFGPRAVPVTAPKTLTGRLYGGGAA
                     LDVVTALLAMRHGVIPGTVGPSRPAPGCDIDLVLGQAREQPLTTALVIARGFGGFTSAL
                     VLGGEPTIRSTQE"
     aSDomain        17491..18384
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_arx17_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="1.40E-26"
                     /label="arx17_PKS_KS.1"
                     /locus_tag="arx17"
                     /protein_end="371"
                     /protein_start="73"
                     /score="85.3"
                     /tool="antismash"
                     /translation="WTHMALAATDLALADAEVRPAELPEYEMAVVTASSSGGTEFGQHE
                     MERLYRRGPSWVSAYQSIAWFYAATTGQVSIRHGMRGPCGVICAEQAGGLDALGQAARL
                     VRGGEARLVVTGGTDAPLSPYGLTAQLANKRLSTSDEPAYLPFDAAATGYLPGEGGAIL
                     IVEAAAAAAARGVCGYGAVLGYAAGFDPPPDSGRPPVLARTIERALATAGRAPSEVDVV
                     FADAVGVPAEDLAEARAITEVFGPRAVPVTAPKTLTGRLYGGGAALDVVTALLAMRHGV
                     IPGTVGPSRPAPGCDID"
     CDS_motif       17929..17967
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arx17_0001"
                     /evalue="2.30E-03"
                     /label="PKSI-KS_m4"
                     /locus_tag="arx17"
                     /protein_end="232"
                     /protein_start="219"
                     /score="11.3"
                     /tool="antismash"
                     /translation="FDAAATGYLPGEG"
     CDS_motif       18001..18021
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arx17_0002"
                     /evalue="9.90E+01"
                     /label="PKSI-KS_m4"
                     /locus_tag="arx17"
                     /protein_end="250"
                     /protein_start="243"
                     /score="-3.5"
                     /tool="antismash"
                     /translation="AAARGVC"
     gene            18510..18773
                     /locus_tag="arx18"
     CDS             18510..18773
                     /NRPS_PKS="Domain: ACP (11-82). E-value: 6.5e-15. Score:
                     47.2. Matches aSDomain: nrpspksdomains_arx18_ACP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1129: acyl carrier protein"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="arx18"
                     /note="arx18"
                     /product="acyl carrier protein"
                     /protein_id="AHX24703.1"
                     /sec_met_domain="PP-binding (E-value: 9e-11, bitscore:
                     33.4, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMQEFSLDDLRAIMRSSAGVEEGIDLDGNIAEMEFSAMGYDSLAL
                     LELGGQLERRYGFPVPEEFASEMHTPAAVVAFVNSQLSKVGN"
     aSDomain        18543..18755
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_arx18_ACP.1"
                     /evalue="6.50E-15"
                     /label="arx18_ACP.1"
                     /locus_tag="arx18"
                     /protein_end="82"
                     /protein_start="11"
                     /score="47.2"
                     /tool="antismash"
                     /translation="AIMRSSAGVEEGIDLDGNIAEMEFSAMGYDSLALLELGGQLERRY
                     GFPVPEEFASEMHTPAAVVAFVNSQL"
     gene            18775..19236
                     /locus_tag="arx19"
     CDS             18775..19236
                     /NRPS_PKS="Domain: Polyketide_cyc (10-133). E-value:
                     2.4e-15. Score: 48.9. Matches aSDomain:
                     nrpspksdomains_arx19_Polyketide_cyc.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1128: cyclase/dehydrase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="arx19"
                     /note="arx19"
                     /product="cyclase"
                     /protein_id="AHX24704.1"
                     /transl_table=11
                     /translation="MVAHTEHEIVIDAPLELVWDMTNDIESWPRLFSEYSEATVLDRSG
                     DAVRFRLALHPDENGKVWSWVSERRPDRATWTVRSQRVETGPFKYMWIYWEYLREGTGV
                     RLRWVQDFEMKPQAPVSDAEMKARLDRNTPVQQRLVKEKVEAAARAAVG"
     aSDomain        18805..19173
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_arx19_Polyketide_cyc.1"
                     /domain_subtypes="Polyketide_cyc"
                     /evalue="2.40E-15"
                     /label="arx19_Polyketide_cyc.1"
                     /locus_tag="arx19"
                     /protein_end="133"
                     /protein_start="10"
                     /score="48.9"
                     /tool="antismash"
                     /translation="IDAPLELVWDMTNDIESWPRLFSEYSEATVLDRSGDAVRFRLALH
                     PDENGKVWSWVSERRPDRATWTVRSQRVETGPFKYMWIYWEYLREGTGVRLRWVQDFEM
                     KPQAPVSDAEMKARLDRNT"
     gene            19243..19701
                     /locus_tag="arx20"
     CDS             19243..19701
                     /codon_start=1
                     /locus_tag="arx20"
                     /note="arx20"
                     /product="monooxygenase"
                     /protein_id="AHX24705.1"
                     /transl_table=11
                     /translation="MAVLVPVVLLCNGLAAGVLAGTLLGGWPLLDTLSAREYVHAHAFF
                     STRYDPFMPACLFGTVLGDGLLAGFGDQAASRALFALAGACALVTVLISLTKNVPINRW
                     VRELDPEDLPEDFGARDPRRYWGKWNRTRAGLAVAALLANCVALWPLL"
     gene            19725..20483
                     /locus_tag="arx21"
     CDS             19725..20483
                     /NRPS_PKS="Domain: PKS_KR (12-174). E-value: 5.3e-13.
                     Score: 41.2. Matches aSDomain:
                     nrpspksdomains_arx21_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="arx21"
                     /note="arx21"
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="AHX24706.1"
                     /sec_met_domain="adh_short (E-value: 1.4e-37, bitscore:
                     120.6, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 2.2e-41, bitscore:
                     133.6, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELELGLRGKKALVTGGSRGVGRGVVLALARAGVDVFTCYREESD
                     ASASLARELKQLGGDHHALRADLADPKQIAELFQEVGRRFGTLDVVVNNAGVISHVPYA
                     ELPVAEWQRIVDVNLTGAHLVIQHAIPLLGDKGSVISIGSKSSEVGIPLRAHYTATKHA
                     LRGLTRSLAKEYGRSGLRFNVLALGVVETEELHALPDDERAEMTKFYSTKTALGRLGTP
                     DEVAGAVAWLASDLSRYVTGATIHVDGGIS"
     CDS_motif       19761..19823
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arx21_0001"
                     /evalue="9.50E-03"
                     /label="PKSI-KR_m1"
                     /locus_tag="arx21"
                     /protein_end="33"
                     /protein_start="12"
                     /score="8.7"
                     /tool="antismash"
                     /translation="LVTGGSRGVGRGVVLALARAG"
     aSDomain        19761..20246
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_arx21_PKS_KR.1"
                     /evalue="5.30E-13"
                     /label="arx21_PKS_KR.1"
                     /locus_tag="arx21"
                     /protein_end="174"
                     /protein_start="12"
                     /score="41.2"
                     /tool="antismash"
                     /translation="LVTGGSRGVGRGVVLALARAGVDVFTCYREESDASASLARELKQL
                     GGDHHALRADLADPKQIAELFQEVGRRFGTLDVVVNNAGVISHVPYAELPVAEWQRIVD
                     VNLTGAHLVIQHAIPLLGDKGSVISIGSKSSEVGIPLRAHYTATKHALRGLTRSLAKE"
     gene            20483..20836
                     /locus_tag="arx22"
     CDS             20483..20836
                     /codon_start=1
                     /locus_tag="arx22"
                     /note="arx22"
                     /product="monooxygenase"
                     /protein_id="AHX24707.1"
                     /transl_table=11
                     /translation="MARDEVFRVVLRMQIRPGLEAEFERTWRDVGDAVVTHPGNLGQWL
                     SRGGEEPGVYYIVSDWVDEARFREFETSERHLEHRRKLHPYRSGGTMTTMTVIAHLPPK
                     GKFADHAEWEKAG"
     gene            20833..21144
                     /locus_tag="arx23"
     CDS             20833..21144
                     /codon_start=1
                     /locus_tag="arx23"
                     /note="arx23"
                     /product="monooxygenase"
                     /protein_id="AHX24708.1"
                     /transl_table=11
                     /translation="MSAVVRVLIYHRTADVEGIEAAYHQTSRDLAGVPGLLGNELLRSV
                     HDPASFVVVSMWESREAFDRWERGAEHKDTTAPLRPFRDTTSGRPFGVYEVSSSYTDY"
     gene            21158..21961
                     /locus_tag="arx24"
     CDS             21158..21961
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="arx24"
                     /note="arx24"
                     /product="NDP-4-ketoreductase"
                     /protein_id="AHX24709.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 1.2e-11, bitscore:
                     35.4, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEIIGRGFLARSAEALAGAHPDAMLFVSGVSSAGEVSEREFSREA
                     EMLYAMLRRCQLRRQKLVYFSTSSIGMYGMLSMRGREDGPVFPRSAYGRHKLAMESVIK
                     AAGTDYLILRLATPVGLYQRSHQFLPAMVRQVLRGSVHIQIGARRDLIDIEHVMAILDD
                     LLEGDLSREVVNIASGVAVPIEDLVRHLEERLGVTARKQYSEVPSERAVSIAKLTRLSS
                     SVAHMGFGPGYYRSVIDRYVEALAEEAVEPHQEPMSDSEPAMSWW"
     gene            complement(22020..22475)
                     /locus_tag="arx25"
     CDS             complement(22020..22475)
                     /codon_start=1
                     /locus_tag="arx25"
                     /note="arx25"
                     /product="hypothetical protein"
                     /protein_id="AHX24710.1"
                     /transl_table=11
                     /translation="MVTGTVGVLAVLGSGLTAGVLFAVALSVLPALFRMPPDRYVYTHQ
                     LIGRNWDPTMPVIVLGSALLDIVLAILATGTARLAAVVGAVLLVGVSAVSHLCNVPLNR
                     QVKRIDPAVLPPDWHDPRPLWRRWHLLRTVLAIAGLVANSLAVSTTG"
     gene            complement(22478..22858)
                     /locus_tag="arx26"
     CDS             complement(22478..22858)
                     /codon_start=1
                     /locus_tag="arx26"
                     /note="arx26"
                     /product="hypothetical protein"
                     /protein_id="AHX24711.1"
                     /transl_table=11
                     /translation="MPYAAITYRVKPGHEDEIAEIFAGFQRVDRPEFRGGTGNQAGRLL
                     GTAVFIKEDVIVRVIHYEGDFAAIGAHMAAQRGVHLIEEALAPYLAQERDTTNAEGFGA
                     YFRNATMRKISELSLDTHPARS"
     gene            complement(22858..23595)
                     /locus_tag="arx27"
     CDS             complement(22858..23595)
                     /NRPS_PKS="Domain: PKS_KR (9-168). E-value: 5.1e-13. Score:
                     41.3. Matches aSDomain: nrpspksdomains_arx27_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="arx27"
                     /note="arx27"
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="AHX24712.1"
                     /sec_met_domain="adh_short (E-value: 1.1e-34, bitscore:
                     111.1, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 3.4e-33, bitscore:
                     106.7, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIETLKGKRVMVTGGTRGIGRASVLAFARAGARVLTCHHTDGENA
                     ARFEKELAALGDGHVVVRADITRPDEVAKLSGVAAEEFGGLDVLVNNVGVDGQVAFGDL
                     TDDEWERVIDHNVTGTYRVTRAVVNLLAAGASVINLGSSVALRGRASGVHYTTSKAALI
                     GFTRALCKELGPRGIRVNAVAPGLTETEPGAGLPPAVVDRIVSMTALGRICQPEDVANA
                     VLFLACDSSSYISGTTINVDGGV"
     aSDomain        complement(23092..23568)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_arx27_PKS_KR.1"
                     /evalue="5.10E-13"
                     /label="arx27_PKS_KR.1"
                     /locus_tag="arx27"
                     /protein_end="168"
                     /protein_start="9"
                     /score="41.3"
                     /tool="antismash"
                     /translation="VMVTGGTRGIGRASVLAFARAGARVLTCHHTDGENAARFEKELAA
                     LGDGHVVVRADITRPDEVAKLSGVAAEEFGGLDVLVNNVGVDGQVAFGDLTDDEWERVI
                     DHNVTGTYRVTRAVVNLLAAGASVINLGSSVALRGRASGVHYTTSKAALIGFTRA"
     CDS_motif       complement(23491..23562)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arx27_0001"
                     /evalue="1.20E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="arx27"
                     /protein_end="35"
                     /protein_start="11"
                     /score="18.0"
                     /tool="antismash"
                     /translation="VTGGTRGIGRASVLAFARAGARVL"
     gene            complement(23592..25082)
                     /locus_tag="arx28"
     CDS             complement(23592..25082)
                     /codon_start=1
                     /locus_tag="arx28"
                     /note="arx28"
                     /product="putative peptide transporter"
                     /protein_id="AHX24713.1"
                     /transl_table=11
                     /translation="MSTTTEHSRTAPSAGAREPRPAFGTLFMLDVWERFGFYTLTAVLV
                     LYAVAPAAQGGLGWPVADAAALFSVWLALTFMFALPGGWLTDRVLGARRALLLGGGLVM
                     AGQLTLALVPRPGNLAGLLVVALGTGLYKPSHQTLFTLVVPGRSRREAGISLLYVGIQL
                     SALIAPLVAGYLGERVDWRLAFGSAAAAMAIGTVTLLVASRSLRTAGMSPPHRLPRPAA
                     RRVLWRGLLIAVATTVILAVPVATGVLTMTGLVMIIGLLTVCLPVVTYPLLYRNPGLGQ
                     QDRRRLRAFLWVFVGWTVFWMLVGQDGSVLNLFGQQATDRQVGGFEVPTSWLQSATPLF
                     ILLVAPVFAWLLPRVGRGTPTAGPVKLATGLFIAGGSFLLMAVAAVLAADGTKVSPLWL
                     LVVYLLHACGELIMAAVGVAAVADALPPAYMSRMIGMMWVFAALGGGLGSQVVRLSVVL
                     PLPVYFAGFGVLVLGMGCLVHARRRVISEAMAERKDVP"
     gene            complement(25098..25478)
                     /locus_tag="arx29"
     CDS             complement(25098..25478)
                     /codon_start=1
                     /locus_tag="arx29"
                     /note="arx29"
                     /product="CurD-like protein"
                     /protein_id="AHX24714.1"
                     /transl_table=11
                     /translation="MAYAAITYDIKPGFEEEISEIFRGFKRVRSADVTDLAGRQAGRIL
                     ATAVFIRDDVLVRVIEYEGDLESIIRHMAKQPGVREVEHKLAPYLTRPRDTETTAGFLM
                     TFQRSLLNTVTEFSVRDAPVTS"
     gene            complement(25490..27076)
                     /locus_tag="arx30"
     CDS             complement(25490..27076)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050: monooxygenase FAD-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="arx30"
                     /note="arx30"
                     /product="FAD-binding monooxygenase"
                     /protein_id="AHX24715.1"
                     /transl_table=11
                     /translation="MYDEEVPVLIVGGGPVGLSAALFLSAQGIAPLLVEKRDGTSLLPR
                     APGLQARTMEIFRSVGVVDDVRALELGDSHAYFDGGIIRVRTFAEIDDAEVIEAPQLDG
                     AAISPEQVMGCGQDRYEQVLLKAATDRGARVRHSTRLVSFEQDDDGVTSVVETAGHRRV
                     IRSRYLVGADGARSGVRATLGLGTTGRGSVFHAMSIYFRSPELTELLEDRRFILCYATA
                     TGSPVGLSRLHGCDPWAAAALYQPDRGESPADFTRERCVEIVRAISGLPGMSVDVVATV
                     PWEGAQRVAENFQVGRVFLAGDAAHVHPPAGGFGANTGIHDAHNLAWKLAAVLREQAGP
                     ALLASYDAERRPLGEAMSEQALVRNRIRHGHESRANSSGDRIIDDIVITLGYRYRSSAV
                     AGDADTGVLPPELDLSGAPGSRAPHVWLSRAGARMSTLDLFGSDWVLLTANQDWYAAAG
                     AVRSRVPLRAHLVGPAAELRETGEDWASAYGVKPDGAVLVRPDGFVAWRSASGSPDRVE
                     TLSGLLSQLTS"
     gene            complement(27260..27943)
                     /locus_tag="arx31"
     CDS             complement(27260..27943)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /locus_tag="arx31"
                     /note="arx31"
                     /product="LuxR family transcriptional regulator"
                     /protein_id="AHX24716.1"
                     /transl_table=11
                     /translation="MIRVILVDDQPLLRASFRALLESEDDITVVGEAADGRGAVELATR
                     LKPDVALLDVQMPGVNGIAATQQIIGNPALAGVHVVILTNFALDEYVFAALRAGASGFL
                     AKDSEPEELLRAVRTVAEGQALLSPDVTKRLIAEFVAQPASVDGGADLEVLTPREREVV
                     RLVGMGMSNDEIAAHMVISPTTAKTHVSRSMTKLKVRDRAQLVVIAYENGLVQPRHERT
                     SRSTD"
     gene            complement(27940..29121)
                     /locus_tag="arx32"
     CDS             complement(27940..29121)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /locus_tag="arx32"
                     /note="arx32"
                     /product="two-component system histidine kinase"
                     /protein_id="AHX24717.1"
                     /transl_table=11
                     /translation="MTVPWTPRLGWPDGVVALCVTIFLTLGTPLVPRGRGIEAPLDLPG
                     YLLLACSGLVLLYRRRYPTAVVLATTLLTIVYYAAAYPGFFQPCAFVIALYTVTSLGYR
                     WLALVTGIGMCAGLTIIASMLSGDADGRILDAPLWVGGWLAAAIVAAETARHRRAYLNE
                     VEQRAADALRTKEEAARLRATEERLRIARELHDSLTHAISLVNVQVGLAVHLFDRDRES
                     SRTALLSVKDASRQAMRELRSTLEVLRKDDEEPDGPSLDQIGELIRKSERPGLDITLRV
                     SGDRQPLPREVDHAAYRIVQESLTNAVRHANTPTLSVEVAYQPQHVTMRIEDEGKVGQP
                     VREGVGIRGMRERVAALGGELHVGPKADGGFAVVATLPLPDKAGKADKGDEQT"
     gene            29300..30136
                     /locus_tag="arx33"
     CDS             29300..30136
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="arx33"
                     /note="arx33"
                     /product="F420-dependent reductase"
                     /protein_id="AHX24718.1"
                     /transl_table=11
                     /translation="MGLPTTVPELDVAGLTEWAGTAEALGFASLGVLDRLVYENVEPVV
                     ALAAAASVTARIDLAATVLIAPYRRDVAVLAKQLASVALLSDGRLTVGVSAGLRQDDYA
                     VDGASYGDRGRRLDAQIDALRRLWSGSAEGVGPRTGGATPSIVVGGNSDAALRRAARLG
                     DGWVAGSGTPAQFSDNVATLRSYWAEERRVGSPRTRALVFYALGEHGPELAEAHLHRYY
                     GFLGPHAEVMAAKAVTDPERLRDVIAAYGDAGCAELVFFPCSGDPRQLELLAKAAL"
     gene            30183..31214
                     /locus_tag="arx34"
     CDS             30183..31214
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042: O-methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="arx34"
                     /note="arx34"
                     /product="putative methyltransferase"
                     /protein_id="AHX24719.1"
                     /transl_table=11
                     /translation="MTTEVTAGGEQNPAAIMRLGSAFAGAKALLSAIELDLFSVLAEKP
                     LARSEIEARLGLNPRVTWEWLSLLVALGMLEHVDGHYRNAPVTGQFLDRAKPSYSGGFL
                     ERANQVLYPAWTHLTDALRTGEQQARHVAADDLFDTPYQDQERVEAFLTMMDSLTSAIG
                     PRLAQAFDWSSVATVVDVGGARGNLLSFLLRAHEHLTGTVFDLAPLREPAARLAEQHGL
                     TGRLGFAAGSFFEDPVPPADVLVIGHVLHDWAPDERQQIVDRAFAAVEPGGSVLVYDCM
                     LGEDDLDIARLTISIHMKLMTPGGAEYLVAEGVGMLEKAGFVDVRTQPLGPLDTLLVGR
                     KPR"
     gene            31436..31963
                     /locus_tag="arx35"
     CDS             31436..31963
                     /codon_start=1
                     /locus_tag="arx35"
                     /note="arx35"
                     /product="biotin carboxyl carrier protein"
                     /protein_id="AHX24720.1"
                     /transl_table=11
                     /translation="MTDEERGNQDGDGSAEVSPWHAEVARLGVTGALDVLSRGIADVVR
                     TAPTMPSRAAVRFGCASIEIEWPTAVPVAPDPPTVTSEPPAGVQPHVVRAPLAGTFHHA
                     PAPGSRPFVGVGDLVEPGQQVGVLEAMKIRTPIAADVRGRVSDILVGDAEAVEFDQPLL
                     VLTPALRADLDA"
ORIGIN
        1 tcagtccggc tggccctggg acatcggcgc cgtggcgaac tccttcatcc ccgcctcgaa
       61 gtcgaccgtc ggacgccagc ccagttcatc gatgagcctt cgtggcgtgg cgaagacgtg
      121 ccggacgtcg ccgatccggt actggcccgt cacgaccggc ggcggggcgc tcgcggcgtc
      181 ggcaagtgtg gcggccagct cgccgatgct cctcggctgt ccactcgcga cggtgtaggc
      241 gcggaacccc gggtcggtcc tcgcaagcgc cgccacgttg gcgccggcca cgtcccggat
      301 gtgcacgaag tcccgcttcg ggccgccgtc ctcgaacacc cgcggtgcct cgccgcgtgc
      361 gaccgccgac cggaagaccg acgccactcc cgagtacgga ctctcgtagg gcatcagggg
      421 gccgtacacg ttgtggtacc gcagcgcggt caccgaggcg ccggtctcgc gggcccagca
      481 cgacacgagc agctcctgcg cgagcttggt gacggcgtag acgttgcgcg gcgggttgag
      541 ctcgtcgtcc tcctcagctg ccgacgccac gaggtcggca ccgcacgtgg ggcagcgcgg
      601 ctcgaaccgg ccggcgtcca ggtcctcccg cgaccggcgg ggcggccgga cgaacccgtg
      661 cacgtcacac gagtaccggc tgtcgccgta gatgaccacg gagctggcga gcaccatgcg
      721 gtccacgccg gccgagatca tctccgcgag caggttcgcg gtgccgaggt cgttgcagtc
      781 gacgtactgg acgacgtcga ggatctcacg accccgtccg accatcgccg cctggtggct
      841 gacgaggtcg atgccgcaca gcgcctgcgc gacggtcgcc cggtcgcgca ggtcgccgtg
      901 gacgaagtcg acctcggcgg gcagttcggc gggcgccctc ccgcggtaga cgtcgggtat
      961 gagcgcgtcc aggacccgga tgtcgtgccc cgcgtcgagc aactggcgga cgacctggga
     1021 accgatgaac ccggcaccgc ctgtgaccag gatgcgcatg gtcagccccg ggcggcgaag
     1081 gccgtgaagt agcggtgctc gtcgacggcg agcacctcgc ggaacagcga gcgcacgatc
     1141 gcggtcgact cgtcgctggg ccggagctga gtgcggtacg cgccggtcct gagcttgccg
     1201 ccggagaccc ggatgatcgc cgcggtgccg aggaacgcca gcgtacggcg aaggtgctcg
     1261 atccgaccgt agcggcggcg ctcgaactcg tggaagttgt ccgaggtcca cacgttgccg
     1321 atgaacaacc cgccgggggc gatgaacgag cgcagccggg tcagcacctc gcggatgtcg
     1381 ccaaggtggt ggatggcgtc gatgcacatc accaggtcgg cggtggggag ctcgtgctgc
     1441 cagaagtcgc cctggaccag ctcgaggtcg tcgtggtcga cccgacgcgc cgcgcgtgcg
     1501 aggccctgcg cggagatgtc gatcgcggtc atgtgccgga cgtgggtcag ctccgcggtc
     1561 atcgcggtga actcgcccgt gccgcacgcg acctccagcg agctgtcgac gtccaccgcg
     1621 taggtccgca ggtaccggcc gatgacctcc ttctggtcga ggaagtcgcc gcgcagggtg
     1681 gggtgctgct cggcgctctc gcggtcccag aagcgggccg cccagtagtc gcggccatcg
     1741 ggagcgatgt tgcggaggat cttgttcccg gactgtgcga ggagttcggc gatcatgagg
     1801 tgccttccgt gaacgggtgc ctcagcgggc ggaggtggcg agttcgacca acaccggaac
     1861 cagctcggcg ggggtgggtt gggcgagcat ctccttgcgg agctggatcg cctcggtccg
     1921 gtacgacagc tggtcgagca gggcgccgac ctcaccgcgg atcgtcgcgg gggagaagtc
     1981 ggccagcggc aggacacggc cggcgccagc cgccgcgacc ctggcggcgt ggaaccggtg
     2041 gtccggcaac tgcggggtca tcagcagcgg cagcccggca cacgcgagcg aggtcatgct
     2101 ggtgccgacg ccgccgtgcg agaccaccgc gtcgcacgcg gggagcagtc ggtacagcgg
     2161 gaccgactcg gtcacgtgga caccggcggg caactcggtg cacagctccc gctgcgcggt
     2221 ggtgatcgcg gcgaccacct cgatgtccag cgtggacagg gcggtgagca cctcgggcag
     2281 caggaagtag gccggatcga gcctgccgta ggtcgtgccc caggtgacgc agacccgcgg
     2341 ccgggttgcc ttgccactgc tccactccgg aggcagtccc ccgccgaaac cgttgtaggg
     2401 cacgtactgg acgggctgcc ggggaccgag cggctcctcg acctggagcg cgaccgggca
     2461 ggggtcgagc gtcagcgcgc cggcggtgtc gaccgcgtcg agcccgtacc tctcccacag
     2521 cggcgcgagg aactgccgct cggcgtcgcg gaagaccggc gcggccatga tgtccggccc
     2581 gtacaggtac cgcacggccg gcacgccgaa cgccgcggcg gcgatggggc cggcgtaggc
     2641 ggtcggttcg aacacgacga gatccgggcg ccagcggcgg ccgaacgcga ccaggtcggg
     2701 gagcatcgcc tcggccagct cggcgaacat cgccgcggcc cggggcgtgc tgccggcggt
     2761 cggccttccc gccacggcgg gagcggccgc gatctgccgc agcttcccga tcacgttgac
     2821 gtccttgccg acggaaaccg ctggcagccc ggtgtggggg atggcgtcgg tgagcgcggg
     2881 ttggctcgcg acgcgcacgt cgtgcccgtg cgcccgcagg gcccaggcga gcggcaccat
     2941 cgggaacaga tgagtgggcc acgcccatgt tacgaacagc acgcgcatac ccggctcgct
     3001 ccctccatcg gatgccgggc gaccggacac gtcccccggc ggcgtgcttc gagcatcggc
     3061 accggtgatc cggagcggct cgaaaaccac gcagcggcgg cacccggtgt ccccatcgag
     3121 ccgcgacggg tgttcgaggg aggttctcga aggtgagcac gcggtggcgg tccgctcacc
     3181 gcacccgagg agaggaggcg gtacggatga ccgtgcggac cgcgctggtc accggtgcga
     3241 accgaggtct cggtcgagcc gtcgcctcgt gcctgcggaa gcgggggtac cgggtggtcg
     3301 tggcggcgcg ggacgtcgga gaagctggcg ccgtcgccgc ggagctgggt gtcggcgtca
     3361 ccccggccgc cctggacgtg accgacccgc gtgccgtggc gcggctggcc gccgacctgt
     3421 ccgtcgtgga catcgtggtg aacaacgcgg gcgtgctgga gacctcgggc gcttcccccg
     3481 catcggtcga cctgtccatg gtggagcacg agatccgggt gaacacgctg ggctcgtggc
     3541 gggtcgcgca ggccttcctg ccgggcatgg tcgcacggag gtggggccgt gtcgtgatgg
     3601 tctccagcgg cacctcgacg ttcacgcacg gcctgttcgg cggaacgccc ggctacaccg
     3661 tttcgaaggt cgggctcaac gccgtgaccg cgttgctggc ggcggagacc gcgggcaccg
     3721 gggtgttggt gaacgcagtc aacccggggt tggtccggac acggatgcgc cccgacgccg
     3781 agcggctgcc cgaggaggcg gccgaggaca tcgcctgggt ggccaccgct ccgaacggct
     3841 cgccgtccgg cgtcctgttc agtcgccgca agatcatcgg ctggtagccc tggccgcagt
     3901 ggaggtgcgc atgtcgggaa tcgtgggctg gatcgactac cgacgggatc tttctcgtgc
     3961 ggcgccggtg gtgcgcgcga tggcggccac catggcggcc aggggacccg acggtgaggg
     4021 tgtgtggacg tcgcggcacg ccgcgctcgg tcaccgcaga ctcgaggtca gcgggtacga
     4081 ccacgtcgac cagccgttcg tgttcgaagt ggacggtcag gtggtggcaa cggcggtctt
     4141 cagcgggaac ctggacaacc tcgccgagtt gcgcaccgtg ctggccagca cgggacggcg
     4201 gctgcgagac ggcggcgagg cggagatcgt gctgcacggg tacttggagt ggggccgcga
     4261 ctgcgtcagc aggatggccg gcgtgttcgc cttcgcggtg tgggacgcgc gggcgcggga
     4321 gttgttcctc ggccgcgacc ggttggggct gaaaccgctc tactactacg agctgccgca
     4381 cgggatcctg ttcgcgtccg agcagaaggc gctgatcgcg cacccgctgg tgaccccgga
     4441 gctcgaccgg gaagggctgg cggagctgct gacctacgcg ggcaccccgg accacggcgt
     4501 gctccggggt ttccggaagc tgcggggcgg gcatgtggcc gtggtccggg agagcggcgt
     4561 ctcgcggtcg cggtactggc agctgtccgc ctaccaccac gacaccgatc tcgccgccac
     4621 cgtggagcgc acgcgggagc tgttgctgga cgccgtccga gcgcagtccc gtgccgctgc
     4681 gccgaccggg ttcctgctct ccggcggcct cgactccagc gtggtggtcg ggctcgcggc
     4741 gaaggcgggg gccggcacgc cattgcgcac ctataccgtg acgttcgccg gctacgacga
     4801 gcagttccgg ccggacttcg tgcggggcac cccggacggg ccgtacgttc gcgcgctcgt
     4861 ggagttcgtg ggcgccgagc accgcgacat cgtgcttgcg accgcggacc tgctcgaccc
     4921 ggtcgcccgg acgagcgcac tgcgggccaa ggacctgccg tcgatgctcg gcgatatgaa
     4981 cacctccctg tacctgctgt gcctggctgc gggtgaccac gtcaaggtgg cgctgtccgg
     5041 ggagaccgcg gactcggtgt tcggcgggaa cgtctacggc gccgaggaga ccggtgggac
     5101 ggctgggcgg accttcccgt gggtgcggtt ccacgagaag cacgccgggc accacgcgat
     5161 gggtggcggt ctgttctccc gcgacctgct cgcccggctg gacctcgtcg agtacggggc
     5221 cgaccgctgc caggagtcgt tcgccgagac accgcaaccc gacgacgtcg acccggtgga
     5281 acggcgggca cggcaggaca cctacctgca gctcacccgc tgggccgaca gccagctcgc
     5341 gcacagcgag cgcaacgcca tggccgcggg gctcgatgtc cgcatgccgt tcgccgacca
     5401 ccggctggtg gactacgtgt tcaacgtgcc gtggcagttg aagtccttcg acggcaaggg
     5461 gaagagcctg ctgcgagccg ccgcggaggg catcgtgccg gacaccgtgt tgaaccggcc
     5521 gaagagcccg ttcccggtct cgatcgaccc cgcctaccaa cgcgtgctcc acgaggagct
     5581 gtcgagggta gcgaacgacc ccgcgtcgcc ggccgccccg ctgctcgagc tcgccaccgt
     5641 ccgcgagcgc ctcgccaccc cggaagcgct cgccgggagc tgggtggcca ggaccgacgt
     5701 cgagatggtc ctggcgttcg accagtggct tcgcgagtac ggcgtacgcc tgacctgctg
     5761 agcacgacaa cgagagtgag gactgtggga atgccgcatg aggagacctt ctgggagtgg
     5821 atggacggcc acgaggagtg gccgcccttc gaccggctgc tcttcctggt gtacggaccg
     5881 aagatcatgg gggtgctgcg tgcgctggcc gagctgggcg tcgcggacga gctgaaggac
     5941 ggcccgctca cgatcgccga gctggccgac cggacaggtg cgcaggagca gccgctgttc
     6001 cgcctgctcc gcaccgcggc cgcgctacgg gtgttccggc agggctccga cggccggttc
     6061 ggactgaccc cggaggcgga gccgctgcgc agcgacctgg acagcagcct gcgcgacctg
     6121 gtcaggttca gcggcgaccc gctgctgacc gcgccctatg ccaacctggc cctcagcgtc
     6181 cgtaccggca aaccggcgtt cgaccaggtc tacggtgcct cgttctacga ccacgtcgag
     6241 gccgtgccgg aggacgcggt gctgttcgac aggacgatga cccagcgcag ctggctgacg
     6301 gccgtgacgc tgctccgcag ggtggatctc agccggttct cccgcatcgc cgatctgggc
     6361 ggcggccagg gccacttcct gggcgaggcg ctcaccaagc actaccagga cgccacagcg
     6421 ctgctgttcg agcgccccac ggtgttggcg agggccaagc cgctgctggc cgagtacggc
     6481 gtcaccgacc gggtgagcct cgaggcaggc gacttcttct cggaggtgcc cgtcggctac
     6541 gacgcctaca tcctcaacgc cgtcctcaac gggttggacg acgagcagtc caagcaggtg
     6601 ctcgcgcggg tgcgggacgc catcggtacg gacaccgagg cccggctgtt catcttcgag
     6661 aaggtgatga ccgagtcggt caacgcctgg gactacagca agctgctcga catggacatg
     6721 ctggtgctgt tcggcggccg ggaacgaacg ctgagcgact ggcgggagct caccgaagcg
     6781 gccgggttcg agctgctgac cacgccggag cggggcggtt cgccctggtc ggcgctggag
     6841 tgccgggcgc gctgagccct gaacgagaaa gggacgtgcc caccggcggg cacgtccctt
     6901 tctcgttagc cggcggtcag ctcaccttgt gctggtaggc gcgggccgcg accggcacgc
     6961 agaccagcag gagcacggac gtccacaaca gaccggccgc taccgggtgg cgcagcggca
     7021 gtgcgggatc ggcaccgatc gggttcgggt tgcccagcag ctcgcgtacc gcgaccacca
     7081 ccgagctgac cgggttccac gaggcaaccg cctgcatcca cggcgccatg ccctcgatgg
     7141 gcacgaacgc gttggacagc cacaccaccg ggaacaccgc ggcgagcccg ccggagatca
     7201 ccgcgcccgg ctcggacacc gcgagaccga gcagcgtgcc ggcccagctc atggcgaacg
     7261 cgaagaacag caacagtccg aacccggcga cgaacccgcc gaagtcggtg tgcgtccgcc
     7321 accccacgag caacgcgaac agcgccatca acaccagtgt gaccgcgttg cggaagatgt
     7381 cggacaccgt ccgcccgacc agcaccgcag gctgggtcat cgggatcgag cggaaccggt
     7441 cgatcagccc tttcctgagg tcgtccgcga ggttcgcccc ggtggtcatc ccgccgaacg
     7501 cgaaggtctg cacgaagatc ccgatcatca cgtactcgcg gtagtttccg tggtccggca
     7561 atgggatcgc ctcgccgaag acgtagctga acagcagcac gaacatgatc ggctgcagca
     7621 tcgtgaagaa cagcgcctgc gggatccgca tggtgttccg caggttccgc tgggtcagca
     7681 gcaggcagtc gagcaccacc gcgcccggtc cgcccgccgg cctggcctgg atctgagccg
     7741 tcatgccggc acctcctccg gaacgggcgc acggtgcccg gtgatggtga ggaacacgtc
     7801 gtcgagcgtc ggttgccgga gaccgaggtc cgccacggcc agccctcgct ctgccagtgc
     7861 gccagcgacc gtggccagcg cccgcatgcc ggtggacacc gggacggaga gcctccggtc
     7921 gtccacgacc gggtcgccgt caccgatcgc ggcaagtacc gcgctggccg cgccctgacc
     7981 ggaccggtcg gccagggtca gttcgatgcg gtcgccgccg gttctccgtt tcaactcggc
     8041 ggcggtgtcg tcggcgatga cgcgacccgc gtcgaccacg acgatccggt cggctatccg
     8101 gtccgcctcc tcgaggtact gcgtggtgag cagcaccgtg gtgccctgtt cgacgagctc
     8161 gccgaccagc tcccacgtcg tcaacctgct gcgcgggtcg agcccggtgg tcggctcgtc
     8221 catcgcgatg acccgtggcc gcgcgatgag gctcgcggcg aggtcgagcc gccggcgcat
     8281 gcctccggag tacgtccgca ccagccggcc ggccgcctca ccgaggtcga accggtcgat
     8341 gagctcgtcg gcccgccgca gcgccgcctg tcggcgcagc cggtgcagcc tgccgaacag
     8401 caccaggttc tcccggcccg tcaggtactg gtccaccgcc gcgtactgac cggacagccc
     8461 cagcaaccgc cgcacctgct gcggctgccg gagcacgtcg tacccgccga ccctcgccca
     8521 gccttcgtcg ggcctgagca gcgtgctgag cacccgaacg gtggtggtct tgccggcccc
     8581 gttcggaccg agcagaccca gcacggagcc ctcctcgacc cacagcccga cgtcgtcgag
     8641 cgcgacgacc tcgccgtacc tcttgaccag cccggcgcac tcgatgaccg cggtcacgac
     8701 cgaggacctt tcgcggcgag ccgctccagc gcggggacga ccgccgacgg cgccggctgg
     8761 gccgcgatct ccgcggcgac ccgccgggcc gccgcggcgt gggcgggatc ctcgagcagc
     8821 tccgtcagca ggcgccgcag gtcgtccgcc gtcgcctctc ggcgcgggat gtaggagccg
     8881 gcaccggtct cggcgagcct gcggcagttg aacagctggt ccgggatctg ggggacgccc
     8941 agctgcggta cgccggccga cagcgcggtc atgatggtgc ccgcgccacc ctgcatgacc
     9001 tgcgccgagc aggtcggtag caccaggtgc agcgggaggt tctccagcac ccggacgttc
     9061 ggcgcgagtg ggccgagcag cccgcgctgc tggctcgtga cggcgaggac cagctcgacg
     9121 tccggtagcc cgcgcacgct gtcgaccagc tccggcagcc cgaacatgcc ttcgtgcagg
     9181 cgggagacgg tggtgcccca cgtgaggcag actcgccggg cctgcggtgg ttcgagcagc
     9241 cagtccggcg cctcggcctg gccgttgtac ggcacgtacc gaatgacctc acgggggtag
     9301 tccacctcga cctgcatgct cggcgggcac gcgtcgacgg tgagggcgcc aagcgtgtcg
     9361 acctccggca ccccgaaccg ggcgaacagc tccggcatga ccgcggcctc cccggcacgg
     9421 cccacgtacg ggtagtccgc cgaccacacg tgccggaccg cgggcacacc gatcgcggac
     9481 gcggcgagca gcgcggcgta cgacgtcggt tcatagatga tcacgtccgg ccgccaaagc
     9541 cggcagtact cgatcaggtc gcccgccatg gcggcggcta cctcggcgaa catgcggaac
     9601 ggcacgacgc ccaacgccct gacccgctcc tgctgggcga cggggtcgtc cggcaccgcg
     9661 acgagtgggc ccatcatgcg gccgaacagc tcgccgaagt cgacgtcctt gccgacccgc
     9721 acagccgtca gcccggagtg gaccaccgtg tccatcaggg ccggctggct cgcgaccctg
     9781 acctcgtggc ccgctgaccg gcacgcccag ccgagcgtgg ccagggggta gtagtgcgac
     9841 ggccagcccc aggtggcgaa gagcaccttc atgtcactgt ccttccagga tccggccgaa
     9901 caccgtggcc aactgctcag cggggccacc ctcgccggcg gaaccgcgcc agcagacgaa
     9961 cccgtccggc cggatcagga cggcttcctc gccctggatg ccgtacacgt ccggcaagcg
    10021 cccgcccacg tcgacgagat ccgcgccgga gccggcggga ccgacagtgc tggcggacag
    10081 ctcgatgccg gtctcccccg cgtacacctt ggccgcgtcg atccactcgc cgccggactc
    10141 ggtggtcagc aggacgaaac cgcgaccgaa caggtccatg gtggacagcc gggtgccgtc
    10201 ccggagcagc gggatgtcgg ccgccctcgt gccgggcagg ccgctgggga cgcgggggtc
    10261 ggcggccggg ccaggagacc ggccgccggt caacaccgcg gccgagtcgt agcaatagcc
    10321 gaacatcacg gtgagctcgt cgaggcgtgg ttcgccggcc tcctcgttct ggcgggccgc
    10381 ggtgcgttcg gcggactggc gcacggtcag ctcgccggct gggcgccgct ccgcgtcgta
    10441 ggtgtcgagc agggcgggac tcgcctgccc gtgcagcacc atggcgagct tccaggccag
    10501 gttctgggcg tcctgggcac cggtgttggc gccgaacccg ccggcgggtg gcatcaggtg
    10561 ggcggagtcg cctgcgagga agacccgtcc cgcctggtag gcgcgggcga tccgggagca
    10621 cacctcccac tcgtcccgga ggtcgatcgt cacctcgagg tcgtcctcgc cgacggcggc
    10681 acgcacgagg ccggtccaga cctcgtcggt gaactgctcg ggcgtctcgc ctttgtccgg
    10741 gtcgtaacgg atgccgaaca tccactggtc gccctcgacc ggggtgagca cgccgaagcg
    10801 ggcggcagga ttgagcgcga ccaccatggt cacctcacgg ccacgcaggg cgtgggagag
    10861 gtcggcgcgg aacagcacgc tcagcgcgtg gaccgtggga gcgaggtcgt ccacctcgat
    10921 gcccagggcc tcgcggacgg agctctggtg cccgtcggcg ccgatcatgt actgggcctg
    10981 cacgatgcgc tgagtgctgg tcgcgcggtc cagcaccacg gcggtgacgc cgtcctcgtc
    11041 ctgcgtgaac gacaggagct ccgtgcggta gcggatgtcc gcgccgcgtt cgaccgcgac
    11101 gtcgcgcagg atcggttcgg ccttgtcctg cccgatgctg acccagtcac tgctcgagac
    11161 ggtgccgaga ccggcgaagg tgctcgactc gatacggcgc acctccttgc ccgccaacga
    11221 ctccgcctgg accagcagtt cgttcccggt cagcggcgga gtgccggtgc ggatgcggtc
    11281 ctcgaccccg gcgccgcgga acagctccat cgtgcgtggg ttgagaccgc gggccctcgg
    11341 gtggatcccg gggcccgggt ggcgctcgat caccatcgga cgaattccgt aggtggtgag
    11401 gaacacggcc gacgacagtc cgacgaagct gccgccgacg atcaggacag gagtgcgcac
    11461 gacggctcca cctcccctta tcggtgataa tttatcggtg ataagttagc cttgccgtga
    11521 ttagaatgtc aaccgtgacg aacgggaagg tggctggcgc cagacgccgc atcgaccgcg
    11581 acaagctcgt ggccgccgcc gtggatctgc tcggtgaagc cggcctggac gggttgtcca
    11641 cccgcaacct ggcggcgaag ctgggagtgc ggcagccggc gctgtactgg cacctgcgca
    11701 acaaggagga acttctcgac cttgtcgcgg aggccatctg cgcgtccttc gcggacttcg
    11761 agtacgacga acagaagagc tggcgggaga acatccacgc tggcatgacc cggttccggg
    11821 cgctgctact gacgatccgg gacagcgcga aactgctggc gcgccgcccg ccacgggggc
    11881 ccaaccgact gcgactggcc gaggccaccg tcaagctgct gcttggcgca ggtttcagca
    11941 agcaggacgc ggcagtgctc tcggtggtcc tgacggactt cgtgatcggc gccgtgagcg
    12001 cgcaggacgc cgcgcgggcc ggtgctggtc cggatgccga ggagttcgcc ggtatcgcgg
    12061 cccccgtgct cactgactac ccccacctcg cgagcgtgct ggagcacttc tcgggggtgg
    12121 atcccgacgc ccagttcgag acgggcctgc agatcttcct cgacggcatg gaacgcaggc
    12181 tggagcggct cgccgcgacg gagcacaccg gcgccgcctc ctcctcctag gcagcgccgg
    12241 gagccgcacc ggtcaaccga tcgtcacgat ctcgagcatc tcctcgagca ccccgctgcg
    12301 gccggttctg ccatggctcg tgtaggagca caccgcgtac cggccagggg ggaaccgcag
    12361 ccgcatcgcc gactcacggc ccgacgagat cggcatcaga ccggttgggg cgcccatgaa
    12421 cacgttgcca ggtggagtgc ccccggtgcg gaacgccagg acgaagtcgc gcacgtcgtc
    12481 ggcggtcgtg ccgtcgtgga cccggttgaa caccacctcc tgcggatggt cgctcaggtt
    12541 gcgcagcagc accgtgcact cggcagggag ccgctccggc atggcgtaga actcccgctc
    12601 cccttcctgc cgcgcctcga tgacgacgtc cacggggacc ttcagctcgt gccgcgccgg
    12661 tccggtggtg cgcagggact ggatccggtc ggccgcgtcg ggttcggcga ggtcgtcgta
    12721 gtcgaggaag tagtacgtgc ccggctcgag gcacaacgtg tgctcgatct gcccgtacga
    12781 ggggtagacg gtcacgccgc cagcgaagtc caccgcctgg ttgagctccg ccctggcgcg
    12841 ggtgtgcacg gccgggtccc atgaacggga ccggttcagg cagtccagga agtaaccgag
    12901 gtcggtgccg gcgggaagcc gcaccagacc ccacttgtgt ccgctcgcgt ccggtgtgct
    12961 gacccggaac gtggcctcgc ccgccggtcg cgggtccggg ctcggcagtg gggggtgctt
    13021 gccgtcgagg acgatgtcga gcacgtcgcc ggcctgggaa cgcatcgcac agtcctttct
    13081 gctgtacccg ttattcgggc cggcgacctt cgaacagcgt gacctgcaac cagttgtcct
    13141 ccgcggtggt gatccgctcg aggtcgacgt ccgcgcgccg gaacagctcc cggtactggc
    13201 tctcgttccg cacctggccg ttggtgtacg ccagcaggcc gatgttggtg atgtcgagga
    13261 acaggtcggg cttctccggt agcagccagt cgctcacgac caacggcgtg cccggcgccg
    13321 ccgcggcgcg gaagttggac agcacgcgca cgcagctgtc gtcatcccag tcacagagga
    13381 tgctcttgag caggtacagg tcaccgcccg ccggcagctc ctccaggaag ctgcccggta
    13441 cgaactccac ccggtcggtg agcccgcgct cggcgatgta gtccttggcc cgctcgacga
    13501 cctccggcag gtcgaacagc acgccgctgg tgtgggggtg tgcttccagc acacgtgaca
    13561 gcagcacgcc gtggctgccg cccacgtcga cgatccgttt ggtgtcggtg aagttcaccc
    13621 gcgggatgag gatgtcggcg gcgaactccg actgctcgcc catggtgtcg gcgaaccagg
    13681 tggactcctc gtcgttctcc ttgtagtaat cccacaaacc cttccccaac gtgcgctcgg
    13741 tgtgctcgtg cccctcgagc accacgttgt gcagctgctc cagcggccgg tacagcccgg
    13801 ggccggtgaa cgacagcacg aagctgacca gcgagcgtcg gccggagcgg agcagcgggg
    13861 tcatcgcact ctcggcgaag cggtcgccgc cgaggtgttc gaccagtccg atcgacgcgg
    13921 ccgcccgcag gaagcgggag gtcgcaccgg gatcggcgga aatcttgctc gcgagctcgg
    13981 cactggtgac cggaccgtcg gccaggtgct cggcgacgcg caggcgagcg gcggcaccga
    14041 cgatctggga cgacatgtag ccgcgggtca gcgccaccag ccgctgggcg gggttgccgg
    14101 tgcccggtgt ccattcggtt gtcatggaag ctcctgtcct tccgaggcgt gcgtcgctcg
    14161 ccacagtgct ctctcctact cgaagccggg tcagtcaggt gctcgaaggc gtggcggcgg
    14221 cgcacaggcg agccggtgct cgacgatcga gtgctgttcg agcccgccgc gtgaggctca
    14281 cgttgtcgcc gtcacctatg cggggagatg aagagatgcc agggcgggta gtgggcctcg
    14341 tcgggctggg tgccatgggt tcgggcatgg ccgcgtgcct gctccgcgcc ggtttgcccc
    14401 ttgtggtcca caacagaacc gccgccgcgg tccgaccgct cgtcgacctg ggtgcccatg
    14461 ccgcggcgac ggcggctgac gcggtcggac aggccgacgt cgtactcgtc agcctcagcg
    14521 acgacgacgc ggtggagtcg gtgctgttcg gcgccgcggc tggcgcgttg cggcccggta
    14581 cggtcgtggt caacacctcc gcgatctccc cgcggtacgc ccgatcttcg gcggagcggc
    14641 tacgcgcggc cggcgccgtg ccggtcgagg ccggggtggt cggcaatccc gagatggcgc
    14701 gggccggccg gctgcgcgtg ctcaccggcg gccgcgccga ggacgccgcg gcggtggccg
    14761 acctgctcga cctcgtgggg gagcaggtgg tccacgtcgg cgaccacggc agcgccgtcg
    14821 tgctcaagct ctgtttcaac ctgctgctgg gtgcccagac cgcggtgctc gcggaggcgg
    14881 tgtcgtacgg caccggtgcc ggtatcgacc gggacgtgct gctcgacgca atcgtccaga
    14941 gtggattctc cagtccggtg ctgaccttcc gcgcctcttt catgcggtcc gggcagtacg
    15001 agcccgcggc cttccgcgcc ggcctgatgg ccaaggacct cggcaacgtg ctgtccgacg
    15061 cgacggagct cgggctcggt ctgccggtgg tggcgcggct cgccgaacgg ttcacccagc
    15121 tcgccggcac ctggccggac agcgacgcgg cagcggtcct gcgcctgcag cacgccgacg
    15181 cggggcgtcc cgaacggacc gccgcatccc gaccctgacc ctcccgagga ggcacgcccg
    15241 tgcaccgaac actcatcgtc gcgcgactga ggacagacga cccccagcgg atcgccgacg
    15301 ccttcggttc gtccgacgag acggaactgc cgcacctggt cggcgtctca cggcggaccc
    15361 tgttcacctt ccacgacctg tacttccacc tcgtcgaggc ggaccaggac atctcgccga
    15421 gcctgtaccg ggcccggtcc cacccgctct acaccgacct caaccagcga ctggcccaac
    15481 tcgtggcgcc gtacgacccg aactggaagg aacccaagga cgccatggca tcgccgttct
    15541 acgtgtggac cgccgagaag gggcgtgagc agtgaccgag cggaggcgac tgaagttcac
    15601 cacggccgac gcggtgccga acacccggcg tggcggggac ctgcgggtga cgttgagccc
    15661 gaagacggtc gggtgcacgt ccggcttcgg tggcgtgctg tggttgcggc cgggcgagtt
    15721 cgtcaccgag cactaccacc cgtactccga ggagttcgtg cacgtggtcg agggctcgct
    15781 ggagatgacg gtggacggcg agcgagtgcc gctcgccccc ggcgactcgc tgtacgtgcc
    15841 gatcggtgct cggcaccggc tggtcaacac cggcaccgag ccggcacggg cggtctttca
    15901 cctgtcccca ctggcgccgc gcccggatct cggccacgtc gacacggagc cgccgctggc
    15961 gccggcacaa ccgcagccgg aggtcggagg agctcctcga tgacgagatc cgttgtcgtc
    16021 accgggatcg gggtggtggc gccgggcgcg gtcggtcgcg agccgttctg ggcactgttg
    16081 accgagggcc gcaccgcgac caggaccatc agcctgttcg acgccgccgc cttccgctcg
    16141 cgagtggggg ccgaggtcga cttcgacccg ttggccgagg gactcacccc gcggcaggtg
    16201 cggcggatgg accgcgccgc ccagttcgcg gtggtgagca tgcgagaagc cgtgcgggac
    16261 agtggcgtcg agttcgaccg cctcgatccc ggccggatcg gcgtcagcat cggcagcgcg
    16321 gtgggctgca ccatcggcct ggaggaggag taccaggtcc tgtccgacaa cgggcgggaa
    16381 tggctggtgg accacagcta cggcgtgcca cacctgtacg gctacatggt gccgagcacg
    16441 ctcgccgtcg aggtggcatg ggaggtggcg gcggagggac cggtcgccct gatctccacc
    16501 gggtgcacgt ccgggttgga cgcggtcaac cacggcgcgg agctgatccg cgagggctct
    16561 gccgatgtcg tactggccgg tgcgacggac gcgccgctgt caccgatcac cagcgcctgc
    16621 ttcgacgcga tcaaggcgac cacacccaac aacgacgacg ccgagcacgc ctcccggccc
    16681 ttcgacgccc atcgggacgg tttcgtgctc ggcgagggtg ccgccgtgct ggtgctggag
    16741 gaggcggccg cggcacgcgc ccgtggggcg cgggcctacg ccgagctggc cgggttcgcg
    16801 agccgcagca acgcgttcca catgaccggt ctgcgccccg acggtcgcga gatggccgag
    16861 gccatccgag tcgccatgga ccgtgccggg gtcgacgccg aggacatcga ctacgtcaac
    16921 gcgcacggtt ccggcacccg gcagaacgac ctgcacgaga ccgcggcgtt caagcgcagc
    16981 ctcggcgagc gcgcgtacca ggtaccggtg agctccatca agtcgatgat cgggcactcg
    17041 ctcggcgcca tcgggtcgct cgagctggtc gcctgcgcgc tggccatcga gcgccacgtc
    17101 gtgccgccga cggcgaacct ccaccacccc gacccggcgt gcgatctcga ctacgtgccg
    17161 ctgaccgcac gcgagtacga gctcgacgcg gtgctcagcg tcggcagcgg tttcggcggg
    17221 ttccagagtg ccgcggtgct cacgaagcca cggtggaagg acgtgtgagg aatggcggct
    17281 gacccggtcg tggtgaccgg taccggtgtc gtcgcgccaa ccggcgtcgg caccgaccag
    17341 cattggcagg ccgtgctcgc cggtaagtcg ggcatcggcc gcatcacccg gttcgacccg
    17401 tctccgtacc cggtcagggt cggcgggcag gtgcccggtt tcgacgccgc cgaacgggtg
    17461 ccgggaaggc tcatcccggc gaccgaccac tggacccaca tggcgctggc ggccaccgac
    17521 ctcgcgctcg ccgacgcgga ggtacggccg gcggagctgc cggagtacga gatggcggtg
    17581 gtcaccgcca gctcgtccgg cggcacggag ttcggccagc acgaaatgga gcggttgtac
    17641 cgcaggggcc cgtcgtgggt cagtgcctac cagtcgatcg cgtggttcta cgcggcgacc
    17701 acggggcagg tgtcgatccg gcacggcatg cgcgggccct gcggggtgat ctgcgcggaa
    17761 caggcgggtg ggctcgacgc actcggccag gccgcccgac tggtccgcgg tggtgaggcg
    17821 cggctggtgg taaccggggg taccgacgcg ccgctcagcc cgtacggcct caccgcccag
    17881 ctcgccaaca agcgcctgtc cacatcggac gagcccgcgt acctgccgtt cgacgccgcg
    17941 gcgacgggtt atcttcccgg tgagggcggg gcgatcctca tcgtcgaggc cgccgccgcg
    18001 gccgctgcga ggggagtgtg cggctacggc gccgtgctcg gctacgcggc ggggttcgac
    18061 ccgccgccgg actccggtcg gccgcccgtg ctggcacgca cgatcgagcg ggcgctcgcg
    18121 accgcgggca gggcaccgtc cgaagtagac gtggtgttcg cggacgccgt cggggtgccg
    18181 gccgaggacc tcgcggaggc gcgcgcgatc accgaggtct tcggtccccg cgcggtcccg
    18241 gtcacggcgc ccaagacgct gaccggccgg ctgtacggcg gcggcgcggc actggacgtg
    18301 gtgaccgcgt tgctcgcgat gcgccacggc gtcataccgg gcacggtcgg cccgtcccgg
    18361 ccggcgcccg gctgcgacat cgacctcgtg ctcgggcagg cgcgggagca gccgctcacc
    18421 accgcgctcg tcatcgccag ggggttcggc ggcttcacct cggcgctggt cctcggcggc
    18481 gaaccaacga tccgttcaac acaggagtga tgatgcaaga gttctctttg gacgacctgc
    18541 gcgccatcat gcgcagcagc gcgggtgtcg aggaggggat cgacctcgac ggcaacatag
    18601 ccgagatgga gttctcggcc atgggatacg actcgctggc actgctggag ctgggcggcc
    18661 agctggagcg caggtacggc ttcccggtac cggaggagtt cgcgtccgag atgcacaccc
    18721 ctgccgcggt cgtggcgttc gtcaactccc agctctcgaa ggtggggaac tgacatggtg
    18781 gcgcacaccg agcacgagat cgtcatcgac gccccgctcg aactcgtctg ggacatgacc
    18841 aacgacatcg agtcgtggcc acggctgttc agcgagtact cggaggcgac ggtcctggac
    18901 cggagcgggg acgccgtccg gttccggctc gcgctgcacc cggacgagaa cggcaaggtc
    18961 tggagctggg tctccgaacg ccggccggac agggcgacct ggaccgtgcg gtcgcagcgg
    19021 gtcgagaccg ggccgttcaa gtacatgtgg atctactggg agtacctgcg tgaaggcact
    19081 ggcgtccggc tgcgctgggt gcaggacttt gagatgaagc cgcaggcacc cgtcagtgac
    19141 gcggagatga aggcgcgcct cgatcgcaac accccggtcc agcagcggct ggtcaaggag
    19201 aaggtcgagg cagccgcacg ggccgcggtc ggctgagccg tgttggcggt cctcgtcccc
    19261 gtcgtgttgc tgtgcaacgg actggccgcc ggtgtactgg ccgggacgtt gctcggtggg
    19321 tggccgttac tggacacgtt gagcgcccgc gagtacgtgc acgcgcacgc gttcttctcg
    19381 accaggtacg acccgttcat gcccgcctgc ctgttcggca ccgtgctcgg cgacggcctg
    19441 ctcgccgggt tcggggacca ggcggccagc cgggccctgt tcgcgctggc gggtgcgtgc
    19501 gcgctggtga cggtgctcat ctccctgacg aagaacgtgc cgataaaccg gtgggtgcgt
    19561 gagctggacc cggaagacct gcccgaggac ttcggcgcac gtgacccccg ccggtactgg
    19621 ggcaagtgga accgcacgcg ggcggggctc gccgtggccg cgttgctggc caactgcgtt
    19681 gcgctctggc cgctcctgtg accagaccac agtggaggaa gatcatggaa ctggaactcg
    19741 gccttcgtgg caagaaggcg ttggtgaccg gtgggagccg tggcgtcggc cgcggcgtgg
    19801 tcctggcgct cgcccgcgcg ggcgtcgacg tgttcacctg ctaccgggag gagagcgacg
    19861 cgagcgcatc gctcgcccgc gagctcaagc agctcggcgg cgaccaccac gcgttgcggg
    19921 ccgacctggc cgacccgaag cagatcgccg agctgttcca ggaggtcggc cgtcggttcg
    19981 gcacgctgga cgtggtggtc aacaacgccg gggtgatcag ccacgtgccc tacgcggagc
    20041 tgccagtcgc ggagtggcag cgcatcgtcg acgtcaacct caccggcgcg cacctcgtca
    20101 tccagcacgc catcccactg ctgggggaca agggttccgt catcagtatc ggctcgaagt
    20161 cctccgaggt gggcatcccg ctgcgggcgc actacaccgc gaccaagcac gcactgcgtg
    20221 gcctgacccg gtctctggcc aaggagtacg gccggagtgg cctgcggttc aacgtcctcg
    20281 ccctgggtgt ggtcgagacc gaggaactgc acgcgctgcc ggacgacgag cgggcggaga
    20341 tgacgaagtt ctacagcacc aagaccgcgc tgggccggct cggcacgccg gacgaggtgg
    20401 cgggggccgt cgcatggctc gcgagcgacc tgtcccggta cgtcaccggc gcgacgatcc
    20461 acgtggacgg aggaatttcc tgatggcacg cgacgaggtc ttccgggtgg tgctgaggat
    20521 gcagatcagg cccggactgg aggcggagtt cgaacggacc tggcgtgatg tcggcgacgc
    20581 cgtcgtcacg catcccggca acctggggca gtggctgtcc cgaggtggtg aggagccggg
    20641 cgtctactac atcgtcagcg actgggtgga cgaggcgcgg ttccgtgagt tcgagaccag
    20701 cgaacggcac ctggagcacc gcaggaagct gcacccgtac cggtccggcg gaacgatgac
    20761 gaccatgacg gtgatcgccc acctgccacc gaaggggaag ttcgctgacc acgccgagtg
    20821 ggagaaggcg ggatgagtgc ggtcgtgcgg gtgctgatct accaccgcac ggcggacgtc
    20881 gaggggatcg aggccgccta ccaccagacc agcagggacc tcgccggcgt gcctggcctg
    20941 ttgggcaacg agctgctgcg ctccgtgcac gacccggcca gcttcgtggt ggtcagcatg
    21001 tgggagagcc gagaagcctt cgaccgctgg gaaagagggg ccgagcacaa ggacacgacc
    21061 gcgccgttgc ggccgttccg ggacaccacg tcgggtcggc ccttcggcgt ctacgaggtc
    21121 agttcctcgt acaccgacta ctgattgggg gcgaccgatg gagatcatcg gccggggttt
    21181 cctcgcccgc agtgcggaag ccctcgctgg cgcccacccg gacgcgatgc tgttcgtgtc
    21241 cggggtctcc agcgccggcg aggtgtccga acgggagttc tcgcgggaag cggagatgct
    21301 gtacgccatg ttgcggcgct gccagctgcg gcggcagaag ctggtctact tctcgacgtc
    21361 gtccatcggg atgtacggca tgctcagcat gcgtggcagg gaggacgggc cggtcttccc
    21421 ccggtcggcg tacggcaggc acaagctggc gatggagtcg gtgatcaagg ccgccggcac
    21481 ggactacctc atcctccggc tcgccacacc cgtcgggctc taccagcgca gccaccagtt
    21541 cctgcccgcc atggtccgcc aggtcctgcg cgggtcggtg cacatccaga tcggtgcccg
    21601 tcgcgacctc atcgacatcg agcacgtgat ggcgatcctc gacgaccttc tcgaggggga
    21661 cctgtcccgg gaggtggtca acatcgcgag cggggtcgcc gtgcccatcg aggacctggt
    21721 acgccacctc gaggaacgac tcggcgtcac cgcgcgcaag cagtactcgg aggtgccgtc
    21781 ggaacgggcg gtctcgatcg cgaagctcac gcggttgagc tcgtcggtgg cgcacatggg
    21841 tttcgggccc gggtactacc ggtcggtcat cgaccggtac gtcgaggcgc tggcggagga
    21901 ggccgtcgag ccgcaccagg agcccatgtc cgacagtgag ccggcgatga gctggtggtg
    21961 atgctggaac cacgggaaag cggggccggg cgtaccggcc ccgctttccc gtggttgcgt
    22021 caccctgtgg tcgacaccgc cagggagttg gccaccaggc cagctatcgc cagcacggtg
    22081 cgcagtaggt gccagcgccg ccacagcggg cgcgggtcgt gccagtccgg ggggagcacg
    22141 gccgggtcaa tgcgcttcac ctggcggttg agcggcacgt tgcacaggtg tgagaccgcc
    22201 gagacgccga ccagcaggac cgcgcccacg accgcggcca gccgggcggt tccggtggcg
    22261 aggatcgcga gcacgatgtc cagcagggcg gaaccgagca cgatgaccgg catcgtgggg
    22321 tcccagttcc gcccgatcag ctggtgggtg tagacgtacc ggtccggtgg catgcggaac
    22381 agtgcgggca ggacgctcaa cgccacggcg aagaggaccc cggccgtgag cccgctgccc
    22441 agcacggcga gcacaccgac agtgcccgtg accacggtca gctccgcgcg ggatgcgtgt
    22501 cgagcgacag ctcggagatc ttgcgcatcg tggcgttgcg gaagtacgcg ccgaaaccct
    22561 cggcgttcgt ggtgtccctc tcctgcgcca ggtacggcgc cagcgcctcc tcgatcaggt
    22621 ggacgcccct ctgcgccgcc atgtgcgcgc cgatcgccgc gaagtcgccc tcgtagtgga
    22681 tgacgcggac gatcacgtct tccttgatga acaccgcggt gcccagcaac ctgcccgcct
    22741 ggttccccgt gccgccccgg aactccgggc ggtcgacgcg ctggaacccg gcaaagatct
    22801 cggctatctc gtcctcgtgt cctggcttca cccggtaggt gatcgccgcg tagggcatca
    22861 gactcctccg tccacattga tcgtcgtgcc cgagatgtag ctcgagctgt cacaggccag
    22921 gaacagcacc gcgttcgcca cgtcctccgg ttggcagatg cgacccagcg cggtcatcga
    22981 gacgatgcgg tccaccaccg cgggcggcag gccggcgccg ggttcggtct cggtgagacc
    23041 gggagccacg gcgttgaccc gaatgccgcg aggacccaac tccttgcaca gcgcgcgggt
    23101 gaagccgatc agcgccgcct tcgacgtcgt gtagtgcacc ccggaggcgc ggccgcgcag
    23161 tgcgacggac gaaccaaggt tgatcaccga cgcccccgcg gcgagcaggt tgacgacggc
    23221 gcgggtcacc cggtaggtgc cggtgacgtt gtggtcgatc acccgctccc actcgtcgtc
    23281 ggtcaggtcc ccgaacgcga cctggccgtc gacacccacg ttgttcacca gcacgtcgag
    23341 cccgccgaac tcctcggcgg cgacgccgga cagcttcgcc acctcgtccg gtcgcgtgat
    23401 gtcggcccgc acgacgacgt gcccgtcgcc cagcgccgcg agctccttct cgaacctggc
    23461 ggcgttctcg ccgtcggtgt ggtggcaggt gagcacgcgg gcaccggcgc gggcgaacgc
    23521 cagcacgctc gcgcgcccga tgccgcgggt cccacctgtc accatgaccc gcttgccctt
    23581 gagagtttcg atcacggcac gtccttccgt tctgccatgg cctccgagat cacccggcgc
    23641 cttgcgtgga cgaggcatcc catgccgagc acgaggacac cgaagcccgc gaagtagacg
    23701 gggagcggca acaccaccga cagccgcacc acctggctgc cgagcccacc gccgagcgcg
    23761 gcgaaaaccc acatcatccc gatcatccgg gacatgtagg ccggcggcag cgcgtccgcg
    23821 acggcggcga caccgaccgc cgccatgatc agctcaccgc acgcgtggag caggtagacc
    23881 accaacagcc acagcgggga gaccttcgtc ccgtcagcgg ccagcacggc cgccaccgcc
    23941 atcaggagga agctgccacc cgcgatgaac aagccggtgg ccagcttgac cggccccgcc
    24001 gtcggcgtgc cgcgtcccac acgtggcagc agccaggcga acaccggagc gaccaggagg
    24061 atgaacagcg gcgtcgctga ctgcagccag ctcgtgggta cctcgaaccc gccgacctgc
    24121 cggtcggtgg cctgctggcc gaacaggttc agcacggagc cgtcctggcc gacgagcatc
    24181 cagaacaccg tccagcccac gaagacccag aggaacgccc ggagacgcct gcggtcctgc
    24241 tggcccagac cggggttgcg atagagcagt gggtaggtga cgacaggcag gcacaccgtg
    24301 agcagaccga tgatcatcac gaggcccgtc atggtcagca cgcccgtggc gaccgggacg
    24361 gccaggatca cggtggtggc gaccgcgatg agcaggccgc gccacagcac tcgtcgtgcc
    24421 gccgggcgcg gcagccggtg cggcggggac atcccggccg tgcgcagcga cctgctggcc
    24481 accagcaggg ttaccgtccc gatcgccatg gcggccgccg cggagccgaa cgccagtcgc
    24541 cagtcgaccc tctcgccgag gtacccggcg accagcggcg cgatcagggc gctcagctgg
    24601 attcccacgt acagcaggct gattcccgcc tcccggcggc tgcggcccgg gacgaccagg
    24661 gtgaacagcg tctggtggct cggcttgtac agcccggtgc cgagcgccac caccagcagt
    24721 cccgcgaggt tgccgggccg cggcaccagt gcgagggtca gctgcccggc catcaccagg
    24781 ccaccgccca gcagcagtgc ccggcgcgcg ccgagcacgc ggtcggtcag ccagccgccg
    24841 ggcagtgcga acatgaaggt gagggccagc cagacgctga acagggccgc cgcgtcggcg
    24901 accggccagc cgaggccgcc ctgtgccgcc ggtgcgacgg cgtagaggac gagcacggcg
    24961 gtcaacgtgt agaacccgaa gcgctcccag acatcgagca tgaacagggt gccgaacgcc
    25021 ggccgcggct cccgggcgcc cgcggacggc gcggtcctgc tgtgctcggt ggttgtggac
    25081 acgatgttcc ccgctgctca ggacgtgacg ggggcgtcgc gcaccgagaa ctcggtgacg
    25141 gtgttgagca ggctgcgctg gaaggtcatg aggaaacccg ccgtcgtctc cgtgtccctc
    25201 ggcctggtca ggtacggcgc gagcttgtgc tcgacctcac gcacgcccgg ctgtttcgcc
    25261 atgtgccgga tgatcgactc gaggtcgccc tcgtactcga tcacgcgcac gaggacgtcg
    25321 tcgcggatga acaccgcggt ggcgaggatg cgcccggcct gccggcccgc gaggtcggtg
    25381 acgtcggccg accgcacccg cttgaacccg cggaagatct ccgagatctc ttcctcgaag
    25441 cccggcttga tgtcgtaggt gatcgccgcg taggccatcg gtccgctcct cagctcgtca
    25501 gttggctcag taggccggac aaggtctcga cccggtcggg agagccgctc gcggagcgcc
    25561 atgcgacgaa cccgtccggc cgcaccagga cagcgccgtc gggcttgacg ccgtatgcgc
    25621 tcgcccagtc ctcgccggtc tcccgcagct ccgccgccgg cccgaccagg tgggcacgca
    25681 gcggcacccg gctccgcacc gcccccgccg cggcatacca gtcctggttc gccgtgagga
    25741 gaacccagtc gctcccgaac aggtccagtg tggacattcg ggcgccggcc cgggacagcc
    25801 acacgtgcgg cgcgcggctg cctggcgcac cggacaggtc gagctccggg ggcagcactc
    25861 cggtgtcggc gtcgcccgcg acagccgagg accggtagcg gtacccgagc gtgatgacga
    25921 tgtcgtcgat gatccggtca ccggagctgt tcgcccttga ctcgtgcccg tggcggatcc
    25981 ggttgcgtac cagggcctgc tcggacatgg cttcgccgag cggccgccgt tccgcgtcgt
    26041 agctggccag cagtgctggg ccggcctgtt ccctgaggac ggccgcgagc ttccaggcga
    26101 ggttgtgcgc gtcgtggatc cccgtgttgg caccgaaccc accggcgggc gggtggacgt
    26161 gggcggcgtc accggccagg aacacccggc ccacctggaa gttctcggcg acccgctgcg
    26221 cgccctccca cggtacggtc gcgacgacgt cgacggacat gcctggcagc ccggagatcg
    26281 cacgtacgat ctcgacgcac cgctcccgcg tgaagtcggc gggcgactcg ccccggtcgg
    26341 gctggtacag cgccgccgcg gcccagggat cgcagccgtg caaccgggac aggccgaccg
    26401 gcgagccggt cgccgtcgcg tagcagagga tgaacctgcg gtcctcgagc agttcggtca
    26461 gctccgggga gcggaagtag atgctcatgg cgtggaagac gctgccgcgc ccggtggtgc
    26521 cgaggccgag cgtggcgcgg accccgctcc tggcgccgtc cgcgccgacg aggtaccgcg
    26581 accggatgac ccggcgatgc ccggcggtct cgacgacgga cgtgacgccg tcgtcgtcct
    26641 gctcgaacga tacgagcctg gtgctgtgcc gtacccgcgc cccgcggtcg gtcgccgcct
    26701 tcaggaggac ctgctcgtag cggtcctggc cgcagcccat cacctgctcg gggctgattg
    26761 ccgcgccgtc cagctggggc gcctcgatga cctcggcgtc gtcgatctcg gcgaaggtgc
    26821 gcacgcggat gatcccgccg tcgaagtagg cgtgcgagtc cccgagctcc aacgcacgca
    26881 cgtcgtccac gacgccgacc gaacggaaga tctccatcgt gcgtgcctgc aggcccggtg
    26941 cgcgggggag cagcgaggtg ccgtcccgct tctcgacgag cagcggcgcg atcccctgtg
    27001 cgctgaggaa gagcgcagcg gagagtccga ccggtccgcc gccgacgatg aggacgggga
    27061 cttcttcgtc gtacatgtgg tccctctctg cgcggccggt cgatcaccgg cggacaggaa
    27121 ccatgtctac ttttcccgac tcaagaagga ctgggggaac gcgcagtggg cgccgcgcgt
    27181 gcttcgaagg gcgtcggccg agtttcgaac ggtccacagg acacggtcga ggagccggtc
    27241 cgggcactgg cgcccgggct cagtcagtgg acctgctcgt acgttcgtgg cgtggctgga
    27301 cgagcccgtt ctcgtacgcg atcactacca gctgcgccct gtcccggacc ttgagcttgg
    27361 tcatcgagcg gctgacgtgg gtcttggctg tcgtcgggct gatcaccatg tgggcggcga
    27421 tctcgtcgtt ggacatcccc atgccgacca gccgtaccac ctcacgttcc cgcggggtga
    27481 gtacctccag gtcggcgccg ccgtccacgc tcgccggctg tgcgacgaac tcggcgatca
    27541 ggcgtttggt gacgtcgggg gacagcaggg cctggccttc cgcgacggtg cgcacggcgc
    27601 gcagcagttc ctccggttcg ctgtccttgg ccaggaagcc cgacgcgccg gcccgcagcg
    27661 cggcgaagac gtactcgtcg agcgcgaagt tcgtcaggat caccacgtgc acgcccgcca
    27721 gcgcggggtt cccgatgatc tgctgggtgg cggcgatccc gttgacgccc ggcatctgca
    27781 cgtccagcag tgccacgtcc ggcttgagac gggtcgcgag ctccaccgcc ccacggccgt
    27841 cggccgcctc gccgacgacc gtgatgtcgt cctcactctc gagcagcgcg cggaagctcg
    27901 cccgcagcag cggctgatcg tccacgagga tcacgcggat catgtttgtt cgtccccttt
    27961 gtcggctttg ccagccttgt ccggcaaggg cagcgtagcc accactgcga acccaccgtc
    28021 ggctttcggg ccgacgtgca gctcaccacc cagcgcggcc acgcgttcgc gcatcccgcg
    28081 gatgcccacg ccctcgcgga ccggctgtcc caccttgccc tcgtcctcga tgcgcatcgt
    28141 gacgtgctgc ggctggtagg ccacctcgac cgacagagtc ggggtgttcg cgtgccggac
    28201 ggcgttggtc agcgactcct ggacgatccg gtacgcggcg tggtcgacct cgcggggcag
    28261 cggctgccgg tcgccggaga cccgcagggt gatgtcgagg cctgggcgct cgctcttgcg
    28321 gatcagttcg ccaatctggt cgaggctcgg gccgtcgggc tcctcgtcgt cctttcgcag
    28381 cacctccaac gtcgagcgca gttcacgcat cgcctgccgg ctggcgtcct tgaccgacag
    28441 gagcgcggtc cgtgagctct cccggtcccg gtcgaacagg tgcaccgcca gtccaacttg
    28501 gacgttcacc agcgagatcg cgtgagtgag gctgtcgtgc aactccctgg cgatccgcag
    28561 gcgctcctcg gtggcgcgca gtcgggccgc ctcctccttg gtccgcaacg cgtccgcggc
    28621 ccgctgctcg acctcgttga ggtacgcccg ccgatgtcgt gcggtctccg ccgcgacgat
    28681 cgcggcggcg agccagccgc cgacccacag cggtgcgtcg aggattcgcc cgtcggcgtc
    28741 gccgctcagc atcgacgcga tgatcgtgag acccgcgcac atcccgattc cggtcacgag
    28801 cgccagccac cggtagccga gcgaggtgac cgtgtacagc gcgatgacga aggcgcacgg
    28861 ctggaagaag ccggggtagg cggccgcgta gtacacgatg gtcagcaacg tggtcgcgag
    28921 caccaccgcg gtggggtacc gccggcggta caacagcacc aggcccgagc acgcaagcag
    28981 gaggtagccg gggaggtcga gaggcgcctc aatgcctcgc ccacgcggaa cgagcggcgt
    29041 accgagcgtg aggaagatcg tcacgcacag ggccaccacc ccgtctggcc agccaaggcg
    29101 tggcgtccag ggcactgtca tgcgcacgcg agccagccta tcgcacgttg tcgcacgcca
    29161 tcacgttgag tgttctcgaa ctgaccgacc gtgtcctcga acggttcacg aatcgttgtc
    29221 gaccggcggc tgacacggtc ggtcacgttg ccggcgagaa gggttcgagg cacgagcggg
    29281 aggcgacatg cgagtcggag tgggactgcc aacgaccgtg ccggagctcg acgtggcggg
    29341 gctgaccgag tgggccggca cggccgaagc actggggttc gcttcgctcg gcgttctgga
    29401 tcgactggtc tacgagaacg tcgaacccgt cgtggcgctg gccgcggcgg cctcggtcac
    29461 agcacggatc gatctggcgg ccaccgtgct gatcgcgccc taccggcggg acgtggcggt
    29521 gctcgccaag cagctcgcga gcgtggcact gctgtctgac gggcggctca ccgtcggcgt
    29581 gtccgccggg ctgcgccagg acgactacgc cgtggacggc gcctcgtacg gcgatcgcgg
    29641 ccggcggctc gacgcgcaga tcgacgcgtt gcgccgactg tggtccggct cggccgaggg
    29701 cgtgggtccg cgcacgggcg gcgcgacacc gtcgatcgtc gtcggcggta acagcgacgc
    29761 ggctctgcgt cgtgcggccc ggctcggcga cggctgggtt gccgggtccg gcaccccggc
    29821 ccagttctcg gacaacgtgg cgacactgag gtcctactgg gcggaggaga ggcgcgtggg
    29881 ctcgccgcgc acgcgggcgt tggtgttcta cgcgctcggc gagcacggcc cggagttggc
    29941 ggaagcgcac ctgcaccggt actacggctt cctcggcccg cacgccgagg tgatggccgc
    30001 caaggcggtc accgacccgg agcgtctccg tgacgtcatc gcggcctacg gcgacgcggg
    30061 ttgcgcggag ttggtcttct tcccgtgctc cggcgatccc cgtcagctcg aactgctcgc
    30121 caaggccgcg ctgtgagccc ggcgagcagg tccaaccacg aaagcagtcg agaggagcag
    30181 cgttgaccac ggaagtgacg gcgggaggcg agcagaaccc ggcggcgatc atgcggttgg
    30241 gcagtgcgtt cgccggcgcg aaggcactgc tgtccgccat cgagctcgac ctgttcagcg
    30301 tgctcgccga gaaaccgctc gcccggagtg agatcgaggc gcggctgggg ctgaaccccc
    30361 gggtcacctg ggagtggctg tcgttgctgg tggcgctcgg gatgctggaa cacgtggacg
    30421 gccactaccg caacgcgccg gtgaccgggc agttcctgga ccgggcgaag cccagctact
    30481 ccggtggctt cctcgagcgc gccaaccagg tcctctaccc ggcgtggacc cacctaaccg
    30541 acgcgctgcg caccggcgag cagcaggcac ggcacgtcgc ggccgacgac ctgttcgaca
    30601 cgccgtacca ggaccaggag cgggtcgagg cattcctcac catgatggac tccctgacgt
    30661 ccgccatcgg cccgcggctg gctcaggcct tcgactggag ctcggtcgcc acggtggtcg
    30721 acgtcggtgg cgcgcgcgga aacctgctgt cgttcctgtt gcgggcgcac gagcacctga
    30781 cgggcacggt gttcgacctg gcgccactgc gcgaacccgc ggcgcggctg gccgaacagc
    30841 acggactgac cggccgcctc ggcttcgcgg cgggcagctt cttcgaggac cccgttccac
    30901 ccgccgacgt gctggtgatc gggcacgtgc tccacgactg ggcgccggac gagcggcagc
    30961 agatcgtcga cagggcgttc gccgcggtcg aacccggtgg gagcgtgctc gtctacgact
    31021 gcatgttggg cgaggacgac ctcgacatcg ctcggctgac catcagcatc cacatgaagc
    31081 tgatgactcc cggtggcgcg gagtacctcg tcgccgaggg cgtcgggatg ctggagaagg
    31141 cgggcttcgt ggatgttcgc acacagccac tcggtccact ggacacgctg ttggtgggcc
    31201 gcaagcccag gtgatcccgg cggttgccag atgaccggtc accctgctgg atgaggagtt
    31261 cgcggatgcg tccatcgacg ccagaagaag aggaacggct ccgggaacgt tggcggagcg
    31321 cgggaagggc gacggtcgag gcgctggccg cgctctgctc ggtgtggacg ggacatccgg
    31381 tgcccgggcg tagcacagtg gaccgtccga tccagcacgt ggggcaggaa cggccatgac
    31441 ggacgaggaa cgagggaacc aggacggcga cggctccgct gaggtgagcc cctggcacgc
    31501 ggaggtggcc aggctcgggg tgacaggggc gctggacgtc ctgagccgcg gcatcgctga
    31561 tgtcgtccga accgcgccga ccatgccgag cagggcggct gtgcggttcg ggtgcgcgag
    31621 tatcgagatc gaatggccga ccgcggtccc cgtggctccg gaccccccaa cggtcacgtc
    31681 cgaaccgccc gcgggagtcc agccacatgt ggtccgggca cccctcgccg gcaccttcca
    31741 ccacgcaccg gcaccgggtt ccagaccgtt cgtcggcgtc ggtgatctcg tcgaacccgg
    31801 ccagcaggtc ggcgtcctgg aagcgatgaa gatacggacc ccgatcgccg cggacgtgcg
    31861 gggaagggtg agcgacatcc tggtcggcga cgccgaggcc gtggagttcg accaaccact
    31921 gctggtactc accccggcac tccgggccga cctcgacgcg tagct
//
