LOCUS       BGC0000201             28528 bp    DNA     linear   BCT 05-JAN-2016
DEFINITION  Streptomyces aureofaciens strain CCM3239 plasmid pSA3239, complete
            sequence.
ACCESSION   BGC0000201
VERSION     BGC0000201
KEYWORDS    .
SOURCE      Streptomyces aureofaciens
  ORGANISM  Streptomyces aureofaciens
            Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
            Streptomyces.
COMMENT     [WARNING] On Jul 27, 2016 this sequence was replaced by KJ396772.2.
            On or before Jul 2, 2014 this sequence version replaced FJ479754.1,
            AY956334.1, HQ003813.1.
            ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2022-11-07 17:41:46
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 58194
            Orig. end    :: 86722
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..822
                     /codon_start=1
                     /gene="aur1PR3"
                     /gene_functions="regulatory (smcogs)
                     SMCOG1041:transcriptional regulator, SARP family (Score:
                     334.5; E-value: 2.7e-101)"
                     /gene_kind="regulatory"
                     /note="essential for auricin biosynthesis"
                     /product="SARP-family auricin specific regulator"
                     /protein_id="ADM72849.2"
                     /transl_table=11
                     /translation="MDIDVLGALTVRENGVSITPTAAKPRQVLALLALHADQVVPVSAL
                     IEELWGEQPPRSARTTLQTYVLQLRGLIATALEGTDGTRTPKDVLVTLPGGYMLSSAGG
                     TSDVREFDRLAGMGYRAMDAGDFPGAARLLREALALWSGPAFADVEGGVQLDMETRRLE
                     ETRLCALDQRIEADLRLGRHRELLAELTVLASRYRIHENLHGQFMLALHRSGRRGEALS
                     VYQRLRATLVRELGIEPSSALRSLQRSILMSGPENPAESPETARKRLARVG"
     subregion       1..28528
                     /aStool="mibig"
                     /contig_edge="False"
                     /label="Polyketide, Saccharide"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..28528
                     /contig_edge="False"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            1..822
                     /gene="aur1PR3"
     gene            1125..1946
                     /gene="aur1PR2"
     CDS             1125..1946
                     /codon_start=1
                     /gene="aur1PR2"
                     /gene_functions="regulatory (smcogs)
                     SMCOG1041:transcriptional regulator, SARP family (Score:
                     314.2; E-value: 3.6e-95)"
                     /gene_kind="regulatory"
                     /product="SARP family transcriptional regulator"
                     /protein_id="ADM72850.2"
                     /transl_table=11
                     /translation="MEIQVLGPLSAEVNGASIVPTAGKPRQILALLALYPGRVMPVPTL
                     MEEIWGTKLPESALTTLQTYILQLRRRLGTALGPGAPGTAKDVLATRHGGYLLQIPQES
                     VDVHAYEALVAGGQIAFDEGDDERAASMLRKALDLWQGPALVDVKVGPILEIEVLRLAE
                     SRLVTTERRIDVDLRLGRHSELLAELTELMARNPQHEGLHSQAMVALYRSGRQATALDV
                     YRRLRARLIGELGVEPSQQLQRLHQAMLRVDPALDVVAGPRRSSTFDLYAA"
     CDS             2063..2332
                     /NRPS_PKS="Domain: PP-binding (10-77). E-value: 4.1e-08.
                     Score: 25.5. Matches aSDomain:
                     nrpspksdomains_ADM72851.2_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1129:acyl carrier protein (Score: 84.5; E-value:
                     6.6e-26)"
                     /gene_kind="biosynthetic-additional"
                     /note="sa22"
                     /product="putative acyl carrier protein"
                     /protein_id="ADM72851.2"
                     /sec_met_domain="PP-binding (E-value: 2.2e-08, bitscore:
                     25.5, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDRLELTELARILRIWGGEDDCVELSEDVQDLYWIELGYDSLSLL
                     QATGSIERKYDVLLDGELLELADTPRSFLRCVNQVLRGRATAAV"
     aSDomain        2093..2293
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ADM72851.2_PP-binding.1"
                     /evalue="4.10E-08"
                     /label="ADM72851.2_PP-binding.1"
                     /locus_tag="ADM72851.2"
                     /protein_end="77"
                     /protein_start="10"
                     /score="25.5"
                     /tool="antismash"
                     /translation="RILRIWGGEDDCVELSEDVQDLYWIELGYDSLSLLQATGSIERKY
                     DVLLDGELLELADTPRSFLRCV"
     CDS             2430..3395
                     /NRPS_PKS="Domain: Polyketide_cyc (15-119). E-value: 2e-10.
                     Score: 32.8. Matches aSDomain:
                     nrpspksdomains_ADM72852.2_Polyketide_cyc.1"
                     /NRPS_PKS="Domain: Polyketide_cyc2 (159-302). E-value:
                     1.8e-07. Score: 23.5. Matches aSDomain:
                     nrpspksdomains_ADM72852.2_Polyketide_cyc2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1128:cyclase/dehydrase (Score: 324.4; E-value:
                     1.2e-98)"
                     /gene_kind="biosynthetic-additional"
                     /note="sa21"
                     /product="polyketide cyclase/dehydrase"
                     /protein_id="ADM72852.2"
                     /transl_table=11
                     /translation="MSVERVHRMSHAVDAAAPAGVLYNVVADTAPWPLFLPDTVHVERL
                     DSTGTTDRFSQWADTDGRPRPTLWRRTLDAHRRRIDFRRERPADPVTTQGGSWSVEELA
                     PGWSRLTLEQDITVAGNRSADVERVLASARDGARSVLGRLGAVAERWRRLDGLLLSFED
                     SVRIPGPGEPVHEFLYRVGSWPGRVAHVVGAEVTEVSAGVQRTSMVNLADDGSAYTTEE
                     VRVCFPAAGRIVFKRTRPHPLLAAHAGEWSVEPDATGVTVVCRHDVLLDAGAVERMLGP
                     GADPARAGRHVREVLGRESRATLEPAQQYARESVRSLRPV"
     aSDomain        2475..2786
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ADM72852.2_Polyketide_cyc.1"
                     /domain_subtype="Polyketide_cyc"
                     /evalue="2.00E-10"
                     /label="ADM72852.2_Polyketide_cyc.1"
                     /locus_tag="ADM72852.2"
                     /protein_end="119"
                     /protein_start="15"
                     /score="32.8"
                     /tool="antismash"
                     /translation="AAPAGVLYNVVADTAPWPLFLPDTVHVERLDSTGTTDRFSQWADT
                     DGRPRPTLWRRTLDAHRRRIDFRRERPADPVTTQGGSWSVEELAPGWSRLTLEQDITVA
                     "
     aSModule        2475..3335
                     /domains="nrpspksdomains_ADM72852.2_Polyketide_cyc.1"
                     /domains="nrpspksdomains_ADM72852.2_Polyketide_cyc2.1"
                     /incomplete
                     /locus_tags="ADM72852.2"
                     /tool="antismash"
                     /type="unknown"
     aSDomain        2907..3335
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ADM72852.2_Polyketide_cyc2.1"
                     /domain_subtype="Polyketide_cyc2"
                     /evalue="1.80E-07"
                     /label="ADM72852.2_Polyketide_cyc2.1"
                     /locus_tag="ADM72852.2"
                     /protein_end="302"
                     /protein_start="159"
                     /score="23.5"
                     /tool="antismash"
                     /translation="SFEDSVRIPGPGEPVHEFLYRVGSWPGRVAHVVGAEVTEVSAGVQ
                     RTSMVNLADDGSAYTTEEVRVCFPAAGRIVFKRTRPHPLLAAHAGEWSVEPDATGVTVV
                     CRHDVLLDAGAVERMLGPGADPARAGRHVREVLGRESRA"
     gene            complement(3679..4296)
                     /gene="aur1R"
     CDS             complement(3679..4296)
                     /codon_start=1
                     /gene="aur1R"
                     /note="auricin-specific repressor of TetR family"
                     /product="auricin-specific repressor of TetR family"
                     /protein_id="ADM72853.2"
                     /transl_table=11
                     /translation="MIKQERAVRTRRALIESAARVFGRRGYAEATLSMISVGAGVSPGA
                     LHFHFENKAAVAAAVEAAAARALRSAAREVYARRTSALQALADSSHALAGLLLSDTVAR
                     AGFQLSREPTYPSSYALPGEWHEYVHRLLAEAAHEDALLPGLNRQSVATTVVAATLGFE
                     VLGRDDPQWLAPRTLAGFWRVVMPCLAAPATLRSLGAAGRGS"
     gene            4524..5294
                     /gene="aur1P"
     CDS             4524..5294
                     /codon_start=1
                     /gene="aur1P"
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 184.2; E-value: 4.3e-56)"
                     /gene_kind="regulatory"
                     /note="auricin-specific activator"
                     /product="auricin-specific activator"
                     /protein_id="AAX57187.2"
                     /transl_table=11
                     /translation="MNQRTMAVLEPHTVAAGANGGFSPAEGPRTPQHVPAQSALWRILI
                     VESNSAEAETLARGLRRHGHEVDIVGTGGEALRVYAEADLVLLDLELPDLDGLEVCRGI
                     RAAHEIPVIAVTARGSELDRVLGLQAGADDYLAKPYGFRELMARMEAVMRRARPTRPAS
                     ATITCGPLSIDSGTREVTLDGVPVETTRKEFDMLYLLASHPDTVIPRKMLMQQVWGDSW
                     SRRTVDTHVSTLRNKIGAGWIITIRGVGFRFGQG"
     gene            5367..6248
                     /gene="aur1O"
     CDS             5367..6248
                     /codon_start=1
                     /gene="aur1O"
                     /product="putative regulatory protein"
                     /protein_id="AAK59995.3"
                     /transl_table=11
                     /translation="MTVTALCHGESCRGADATGRTRRRAADRGSRLCRPCREHLAAGLG
                     EVAHLYEECGRVLGGAGPGSLRERTTGGESTGLPFNGAAADVRARMVSVLGSWSGLVAQ
                     QRGLTAPPRTVADLTAFLLRNADWLAAHPAAGEVCDEVARLVRAGRRAAFPEPARTFRL
                     GTCPEPGCSGALALSVRGAERDADRAVVCDADPAHRWTSDRWSELSDSLESGRAPGAAA
                     APAPAPAPAPAPATERWLTAADIAQLWHTPTGTVYRLASEERWRRRNRAGRTFYAEGDV
                     RACFARRAQARA"
     gene            6519..7985
                     /gene="aur1A"
     CDS             6519..7985
                     /codon_start=1
                     /gene="aur1A"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050:monooxygenase FAD-binding (Score: 576; E-value:
                     1.3e-174)"
                     /gene_kind="biosynthetic-additional"
                     /product="auricin polyketide oxiygenase"
                     /protein_id="AAX57188.2"
                     /transl_table=11
                     /translation="MDAPVIVVGAGPAGMMLAGELRLAGVAVIVLERLERRTGESRGLG
                     FTARTLETFDQRGILARFGDIERSTLGHFGGLPLDFGVLDGACQAAKTVPQSVTETHLE
                     EWATGLGADVRRGHEVLSVHDDGDTVAVEVRGPGGTHTLRADWLVGCDGGRSTVRKAAG
                     FDFPGTAATMEMFLADIKGIELKPRMIGETLPGGMVMVGPLPGGTTRIVVCERGTPPRR
                     REAPPSFEEVAAAWQRLTGEDISAAEPVWVSAFGDAARQVTEYRRGRVLLAGDAAHIHL
                     PAGGQGMNTGIQDAVNLGWKLASVVLGRAPLALLDTYHGERHPVGRRLLMNTRAQGLLF
                     LSGAEVQPLRDSLRELMAYEDVARHLAAMVTGLEITYDVGKGGHPLLGRRMPGLELAGP
                     GGRTSAAALLCPARGVLLDLADNPRLRQRAAAWGDRVDTVTARPAGAAGGELPDDTTAL
                     LIRPDGYVAWAAPGSHHDLPMALERWFGPA"
     gene            8160..8807
                     /gene="aur1B"
     CDS             8160..8807
                     /codon_start=1
                     /gene="aur1B"
                     /gene_functions="regulatory (smcogs) SMCOG1057:TetR family
                     transcriptional regulator (Score: 63; E-value: 8.1e-19)"
                     /gene_kind="regulatory"
                     /product="TetR family transcriptional regulator"
                     /protein_id="AAX57189.1"
                     /transl_table=11
                     /translation="MATPLATIERAPSGPAGERREIVRAARTVLAREGWTRCTAEATAA
                     EAGVTADTVALHFPDHEQLLLGVLLDSSASVAAALAAVADSHLEEVTDLEADLIALGRA
                     WLAPLEAFREHFAIVRHISAEVTRLPTEAVDKWQATGPRQARRELARRLRRLASMGLLD
                     ISDAEQAAERFILLVPSGVVQRSFLGALPLPRDEADALIADGVADFIRLYRP"
     gene            8890..9222
                     /gene="aur1C"
     CDS             8890..9222
                     /codon_start=1
                     /gene="aur1C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1225:Polyketide synthesis cyclase (Score: 148.1;
                     E-value: 1.3e-45)"
                     /gene_kind="biosynthetic-additional"
                     /product="auricin polyketide cyclase"
                     /protein_id="AAX57190.1"
                     /transl_table=11
                     /translation="MTHSNLIVARMDSMSSDQVAKLFTEFDKTDMPGRMGTLRRRLFMY
                     KGLYFHLQDFAEDDGGQRIQESRTDPRFMRISHDLLPFIQPYDPATWRTPADAMATRFY
                     DWSASE"
     gene            9260..10528
                     /gene="aur1D"
     CDS             9260..10528
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (5-414). E-value:
                     1.3e-51. Score: 167.7. Matches aSDomain:
                     nrpspksdomains_aur1D_PKS_KS.1"
                     /codon_start=1
                     /gene="aur1D"
                     /gene_functions="biosynthetic (rule-based-clusters) T2PKS:
                     t2ks"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 468.4; E-value:
                     3.6e-142)"
                     /gene_kind="biosynthetic"
                     /product="auricin polyketide beta-ketoacyl synthase alpha
                     subunit"
                     /protein_id="AAX57191.1"
                     /sec_met_domain="t2ks (E-value: 1.1e-237, bitscore: 779.7,
                     seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRRVVITGIGVLAPGGIGTTAFWNLLSSGRTATRGITLFDPAPF
                     RSRVAAEVDFHPERHGLTSLEVRRMDRAAQFGVVATREALADSGLDLAAFDPYRIGIAM
                     GTGVGAISGLDTAYRVASDEGRIAQVDHMYAPGHLYDHFVPSSFATEVAWAVGAEGPST
                     VVSTGCTSGIDSVAHAVDLIREGSADIMITGATDAPISPLTLACFDAIKATTALNEEPE
                     TASRPFDATRKGFVLGEGAAAFVLEELGAARRRGAHVYAEIAGYASRSSAFHMTGLRPD
                     GREMAEAITVALDEARLDPGDLDYVNAHGSGTRQNDLHETAAYKLALGPHAHRTPVSSV
                     KSMIGHSLGSVGSMEIAASVLAMEHHVVPPTANLRTPDPECDLDYVPLVARDHRTDAVL
                     TVSSGFGGFQSAMVLARPDRRTA"
     aSDomain        9275..10501
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_aur1D_PKS_KS.1"
                     /domain_subtype="Iterative-KS"
                     /evalue="1.30E-51"
                     /label="aur1D_PKS_KS.1"
                     /locus_tag="aur1D"
                     /protein_end="414"
                     /protein_start="5"
                     /score="167.7"
                     /tool="antismash"
                     /translation="VITGIGVLAPGGIGTTAFWNLLSSGRTATRGITLFDPAPFRSRVA
                     AEVDFHPERHGLTSLEVRRMDRAAQFGVVATREALADSGLDLAAFDPYRIGIAMGTGVG
                     AISGLDTAYRVASDEGRIAQVDHMYAPGHLYDHFVPSSFATEVAWAVGAEGPSTVVSTG
                     CTSGIDSVAHAVDLIREGSADIMITGATDAPISPLTLACFDAIKATTALNEEPETASRP
                     FDATRKGFVLGEGAAAFVLEELGAARRRGAHVYAEIAGYASRSSAFHMTGLRPDGREMA
                     EAITVALDEARLDPGDLDYVNAHGSGTRQNDLHETAAYKLALGPHAHRTPVSSVKSMIG
                     HSLGSVGSMEIAASVLAMEHHVVPPTANLRTPDPECDLDYVPLVARDHRTDAVLTVSSG
                     FGGFQSAMVL"
     gene            10525..11742
                     /gene="aur1E"
     CDS             10525..11742
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (6-402). E-value:
                     3.5e-25. Score: 80.6. Matches aSDomain:
                     nrpspksdomains_aur1E_PKS_KS.1"
                     /codon_start=1
                     /gene="aur1E"
                     /gene_functions="biosynthetic (rule-based-clusters) T2PKS:
                     t2clf"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093:Beta-ketoacyl synthase (Score: 642.7; E-value:
                     3.2e-195)"
                     /gene_kind="biosynthetic"
                     /product="auricin polyketide beta-ketoacyl synthase beta
                     subunit"
                     /protein_id="AAX57192.2"
                     /sec_met_domain="t2clf (E-value: 7.8e-207, bitscore: 677.6,
                     seeds: 26, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSARILVTGIGVAAPSGLGVEDFWSVTRIGKNAIGPVTRFDASAY
                     PSRLAGEIHGFEPKEHLPGRLVPQTDRVTQLALVAADCAFADAGIEPGTIDPYAMGVVT
                     AAGAGGFEFAENELRKLWSEGAKHVSAYQSFAWFYAVNSGQISIRNGLRGPAGVVISDQ
                     AGGLDALAQARRQLRKGSKLIATGGFDAPICSLGWASHLHGGLMSTSDEPERAYLPFDD
                     AAAGYVPGEGGAMLILEDEDSARDRGARTVYGEFAGYGATLDPKPGSGREPGLRRAIDV
                     ALTDAACHPAEVDVVFADGAATPRLDREEAEAITAVFGPRAVPVTVPKTMTGRINSGGA
                     PIDVVSAVLSMREGLIPPTTNVELSDAYDLDLVAVRPRTASVRTALVLARGRGGFNSAV
                     VVRAVD"
     aSDomain        10543..11730
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_aur1E_PKS_KS.1"
                     /domain_subtype="Iterative-KS"
                     /evalue="3.50E-25"
                     /label="aur1E_PKS_KS.1"
                     /locus_tag="aur1E"
                     /protein_end="402"
                     /protein_start="6"
                     /score="80.6"
                     /tool="antismash"
                     /translation="VTGIGVAAPSGLGVEDFWSVTRIGKNAIGPVTRFDASAYPSRLAG
                     EIHGFEPKEHLPGRLVPQTDRVTQLALVAADCAFADAGIEPGTIDPYAMGVVTAAGAGG
                     FEFAENELRKLWSEGAKHVSAYQSFAWFYAVNSGQISIRNGLRGPAGVVISDQAGGLDA
                     LAQARRQLRKGSKLIATGGFDAPICSLGWASHLHGGLMSTSDEPERAYLPFDDAAAGYV
                     PGEGGAMLILEDEDSARDRGARTVYGEFAGYGATLDPKPGSGREPGLRRAIDVALTDAA
                     CHPAEVDVVFADGAATPRLDREEAEAITAVFGPRAVPVTVPKTMTGRINSGGAPIDVVS
                     AVLSMREGLIPPTTNVELSDAYDLDLVAVRPRTASVRTALVLARGRGGFNSAVVVR"
     CDS_motif       11182..11220
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aur1E_0001"
                     /evalue="9.90E-04"
                     /label="PKSI-KS_m4"
                     /locus_tag="aur1E"
                     /protein_end="232"
                     /protein_start="219"
                     /score="12.3"
                     /tool="antismash"
                     /translation="FDDAAAGYVPGEG"
     gene            11840..12124
                     /gene="aur1F"
     CDS             11840..12124
                     /NRPS_PKS="Domain: ACP (17-87). E-value: 1.7e-17. Score:
                     55.4. Matches aSDomain: nrpspksdomains_aur1F_ACP.1"
                     /codon_start=1
                     /gene="aur1F"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1129:acyl carrier protein (Score: 112.6; E-value:
                     1.2e-34)"
                     /gene_kind="biosynthetic-additional"
                     /product="auricin polyketide acyl carrier protein"
                     /protein_id="AAX57193.2"
                     /sec_met_domain="PP-binding (E-value: 2.8e-12, bitscore:
                     38.0, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKGSILSKQEFTFDDLKRILLEGAGADEGVDLDGDILDSEFETLG
                     YESLALLETGGRIEREFGITLDDDVFTDNPTPRSLVTAINESLSALVDA"
     aSDomain        11891..12100
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_aur1F_ACP.1"
                     /evalue="1.70E-17"
                     /label="aur1F_ACP.1"
                     /locus_tag="aur1F"
                     /protein_end="87"
                     /protein_start="17"
                     /score="55.4"
                     /tool="antismash"
                     /translation="RILLEGAGADEGVDLDGDILDSEFETLGYESLALLETGGRIEREF
                     GITLDDDVFTDNPTPRSLVTAINES"
     gene            12217..13002
                     /gene="aur1G"
     CDS             12217..13002
                     /NRPS_PKS="Domain: PKS_KR (7-162). E-value: 2.2e-11. Score:
                     35.8. Matches aSDomain: nrpspksdomains_aur1G_PKS_KR.1"
                     /codon_start=1
                     /gene="aur1G"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     252.9; E-value: 5.2e-77)"
                     /gene_kind="biosynthetic-additional"
                     /product="auricin polyketide ketoreductase"
                     /protein_id="AAX57194.1"
                     /sec_met_domain="adh_short (E-value: 1.2e-36, bitscore:
                     117.2, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDQDKRVAVVTGATSGIGLAVARLLAAQDHRVFIGARSAENVAQ
                     TVKELQDEGLEVDGAVVDVRSTDGVRAWIQAAVDRFGSVDVVVNNAGRSGGGVTADIAE
                     ELWHDVIDTNLNSVFRVTREALTTGGLRAKDRGRIINIASTAGKQGVVLGAPYSASKHG
                     VVGFTKALGNELAPTGITVNAVCPGYVETPMAQRVRQGYAAAYDATEEAILEKFQAKIP
                     LGRYSTPEEVAGLVGYLASDAAASITLQALNVCGGLGNF"
     aSDomain        12238..12702
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_aur1G_PKS_KR.1"
                     /evalue="2.20E-11"
                     /label="aur1G_PKS_KR.1"
                     /locus_tag="aur1G"
                     /protein_end="162"
                     /protein_start="7"
                     /score="35.8"
                     /tool="antismash"
                     /translation="VAVVTGATSGIGLAVARLLAAQDHRVFIGARSAENVAQTVKELQD
                     EGLEVDGAVVDVRSTDGVRAWIQAAVDRFGSVDVVVNNAGRSGGGVTADIAEELWHDVI
                     DTNLNSVFRVTREALTTGGLRAKDRGRIINIASTAGKQGVVLGAPYSASKH"
     CDS_motif       12244..12312
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aur1G_0001"
                     /evalue="4.30E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="aur1G"
                     /protein_end="32"
                     /protein_start="9"
                     /score="19.4"
                     /tool="antismash"
                     /translation="VVTGATSGIGLAVARLLAAQDHR"
     gene            13037..13999
                     /gene="aur1H"
     CDS             13037..13999
                     /NRPS_PKS="Domain: Polyketide_cyc2 (7-149). E-value:
                     3.7e-13. Score: 41.9. Matches aSDomain:
                     nrpspksdomains_aur1H_Polyketide_cyc2.1"
                     /NRPS_PKS="Domain: Polyketide_cyc2 (158-310). E-value:
                     2.2e-11. Score: 36.2. Matches aSDomain:
                     nrpspksdomains_aur1H_Polyketide_cyc2.2"
                     /codon_start=1
                     /gene="aur1H"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1128:cyclase/dehydrase (Score: 463.4; E-value:
                     5.9e-141)"
                     /gene_kind="biosynthetic-additional"
                     /product="auricin polyketide cyclase/dehydratase"
                     /protein_id="AAX57195.1"
                     /transl_table=11
                     /translation="MTQPGLREVEHEITVSAPAAAVYRLIAEVVNWPRIFPPTIYVDQV
                     PEGPGEERIRIWATANGEAKNWTSRRTLDAEALRITFRQEVTAPPVAAMGGTWIIEELS
                     AQESRVRLLHDYRAVDDDADSLAWIDEAVDRNSRSELAALKKNVEAAHAAEELTFSFED
                     TVQIEGSAKDVYDFVNEADRWHERLPHVATVRLREDTPGLQELEMDTRAKDGSVHTTKS
                     YRVTFAHHRIAYKQTTLPALMTLHTGYWTFEENEGGVAASSQHTVTINTDNIARILGES
                     ATVETAKRYVHTALSTNSTATLHHAKAYAEGIARGGKKD"
     aSDomain        13058..13483
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_aur1H_Polyketide_cyc2.1"
                     /domain_subtype="Polyketide_cyc2"
                     /evalue="3.70E-13"
                     /label="aur1H_Polyketide_cyc2.1"
                     /locus_tag="aur1H"
                     /protein_end="149"
                     /protein_start="7"
                     /score="41.9"
                     /tool="antismash"
                     /translation="EVEHEITVSAPAAAVYRLIAEVVNWPRIFPPTIYVDQVPEGPGEE
                     RIRIWATANGEAKNWTSRRTLDAEALRITFRQEVTAPPVAAMGGTWIIEELSAQESRVR
                     LLHDYRAVDDDADSLAWIDEAVDRNSRSELAALKKNVE"
     aSModule        13058..13966
                     /domains="nrpspksdomains_aur1H_Polyketide_cyc2.1"
                     /domains="nrpspksdomains_aur1H_Polyketide_cyc2.2"
                     /incomplete
                     /locus_tags="aur1H"
                     /tool="antismash"
                     /type="unknown"
     aSDomain        13511..13966
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_aur1H_Polyketide_cyc2.2"
                     /domain_subtype="Polyketide_cyc2"
                     /evalue="2.20E-11"
                     /label="aur1H_Polyketide_cyc2.2"
                     /locus_tag="aur1H"
                     /protein_end="310"
                     /protein_start="158"
                     /score="36.2"
                     /tool="antismash"
                     /translation="FSFEDTVQIEGSAKDVYDFVNEADRWHERLPHVATVRLREDTPGL
                     QELEMDTRAKDGSVHTTKSYRVTFAHHRIAYKQTTLPALMTLHTGYWTFEENEGGVAAS
                     SQHTVTINTDNIARILGESATVETAKRYVHTALSTNSTATLHHAKAYA"
     gene            14002..16326
                     /gene="aur1I"
     CDS             14002..16326
                     /NRPS_PKS="Domain: PKS_KR (528-707). E-value: 4.3e-10.
                     Score: 31.6. Matches aSDomain:
                     nrpspksdomains_aur1I_PKS_KR.1"
                     /codon_start=1
                     /gene="aur1I"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050:monooxygenase FAD-binding (Score: 556; E-value:
                     1.5e-168)"
                     /gene_kind="biosynthetic-additional"
                     /product="auricin polyketide oxygenase-reductase"
                     /protein_id="AAX57196.2"
                     /transl_table=11
                     /translation="MSGDYSETQVIVVGAGPVGLLLAGELRLAGTDVVVLDKLTAPTTE
                     SRASTLHSRTMEILDTRGLLDGLGDIPNDPSGHFGGIPFDLALPGPYPGQWKVAQTRLE
                     EVLGQWAADLGADIRRGHELTSLTETGDLVTAEARGPDGTVSTVRAAYAVGCDGEHSAV
                     RRLGGFEFPGTGAERELLRADVAGIDIPGRRFERLEGGLAIAARRPDGVTRVMVHEFGA
                     RPRPGAPSFEEVADTWKRITGEDIGGGTPLWVNSFGDASRQAASYRKGRLLLAGDAAHQ
                     QMPIGGQALNLGLQDAFNLGWKLAAVVSGHGGEALLDSYHEERHAVGRAVQANIRTQAL
                     LLLGGPEVDAIREVFAELTGHEDVRTHLAGMITGLDVRHGAGSQDPAAGLRVPQAGAVG
                     EEGGTTVFELLRPGRGLLLLAPGDEARREELRAAAAPWRDRVRIATAAGADGEAGPAAL
                     LVRPDGHVAWSDGTPDTAPGEDLTAALERWFGPAALRPPRQAAPREAVRVTPVTAAREV
                     RGGGTDRLAGRTALVTGSSRGMGRAAAIRLAEEGALVAVHYTSDGAAAEEVVASVEKDG
                     GRAFAIRAELGVPGDVESLFGALEADLLERTGSTDLHILVNNAGVMGGVGPADITPDQF
                     DRIFAVNAKAPFFLIQRALRNMPDGGRIINISSGLTRFANPDEIAYAMSKGALEQLALH
                     YAKALGPRGITINSVAPGITRNGNPVFDIPEAVEQMASLSAFNRVGEPEDVADVVAFLA
                     TDEARWITGSFVDATGGTLLG"
     aSDomain        15586..16122
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_aur1I_PKS_KR.1"
                     /evalue="4.30E-10"
                     /label="aur1I_PKS_KR.1"
                     /locus_tag="aur1I"
                     /protein_end="707"
                     /protein_start="528"
                     /score="31.6"
                     /tool="antismash"
                     /translation="TALVTGSSRGMGRAAAIRLAEEGALVAVHYTSDGAAAEEVVASVE
                     KDGGRAFAIRAELGVPGDVESLFGALEADLLERTGSTDLHILVNNAGVMGGVGPADITP
                     DQFDRIFAVNAKAPFFLIQRALRNMPDGGRIINISSGLTRFANPDEIAYAMSKGALEQL
                     ALHYAKALGPRGITIN"
     gene            16474..17949
                     /gene="aur1J"
     CDS             16474..17949
                     /codon_start=1
                     /gene="aur1J"
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 216.6; E-value:
                     7.3e-66)"
                     /gene_kind="transport"
                     /product="major facilitator superfamily transporter"
                     /protein_id="AAX57197.2"
                     /transl_table=11
                     /translation="MYPSTTNPPVGERTRWALVAVLAANMLVDALEVSATLVAMPAVGA
                     DLGAGAAGLQWLVSGFAAGFGGLLLLGGRLVEGLGRRRVFLAALLVFAAASLAGALTDS
                     LAALTATRVLKGFCVALTAPTGLAIITSAVPEGAARRRAVSLYSLFGAAGFCAGLLLSG
                     LFTGAGWRWTLAFPAPVALLLLAAGARLVPRDVRDSGARDAGVRDAGVRGAGVRGAGVR
                     GGGLRGPGRHAAACGAALTGAVLLLVYGLAHLAGPGREPVRAAAAFAGAALLGAVFVTA
                     ERRSPRPLVPPVLLRHGPLLRSALGAAALNGSYVGFLLVASLHLRETGRSPWQTALVFL
                     PAAAPLALSALHSARIAVRLGPARAVAAGAVLAPLGYALYPRAPDADPRWTVLLPATAC
                     VGAAFALAFTALHLQATGAVPARLQGAAGGLYQTFVQAGAALTAAPVAALYTVGRAPAL
                     CLVTVIGAAGACVALGGLVPAARAAAAPPPNHP"
     gene            18015..18392
                     /gene="aur1K"
     CDS             18015..18392
                     /NRPS_PKS="Domain: PKS_PP (28-111). E-value: 2.4e-10.
                     Score: 32.5. Matches aSDomain:
                     nrpspksdomains_aur1K_PKS_PP.1"
                     /codon_start=1
                     /gene="aur1K"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /product="hypothetical protein"
                     /protein_id="AAX57198.1"
                     /sec_met_domain="PP-binding (E-value: 3.3e-08, bitscore:
                     24.9, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTLHMSQTYETDNGLVHMTPPDMAVLNAVGLPERTRILEQYVRE
                     ELGRILGIEPWMVDTTGRPMGCLGIGSISGIELQYRMENTLGVDVNLQRLLLANSAQEL
                     IDCLAGQFGPEAHLHGAPVPA"
     aSDomain        18099..18347
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_aur1K_PKS_PP.1"
                     /evalue="2.40E-10"
                     /label="aur1K_PKS_PP.1"
                     /locus_tag="aur1K"
                     /protein_end="111"
                     /protein_start="28"
                     /score="32.5"
                     /tool="antismash"
                     /translation="AVGLPERTRILEQYVREELGRILGIEPWMVDTTGRPMGCLGIGSI
                     SGIELQYRMENTLGVDVNLQRLLLANSAQELIDCLAGQ"
     gene            18389..19216
                     /gene="aur1L"
     CDS             18389..19216
                     /codon_start=1
                     /gene="aur1L"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1012:4'-phosphopantetheinyl transferase (Score: 144;
                     E-value: 6.9e-44)"
                     /gene_kind="biosynthetic-additional"
                     /product="4'-phosphopantetheinyl transferase"
                     /protein_id="AAX57199.2"
                     /transl_table=11
                     /translation="MTATTLLPAARPVVHHQDLDRADFTLSADRVDLWLIRRPTGADAE
                     ALAIEELDESERKRTDSFIRRTDGMLYAAAHVAVRRLLGRYTATRPEDVRFMREPCPGC
                     GEPHGRPALSPPPPPLHYSLSHSGGVAMIGVGTVPLGVDVEKLPGAETVDICSKALHPQ
                     EQLEIAEAEEGEERRQLFGQTWTRKEAFLKGIGTGLSRSPAEDYLGTDHDRHPDGWTMV
                     GVPADGQHAAAVAVAGPAPARVDVRWVPDAWLSVGHTVCSGTAPGPRPAALAG"
     gene            19247..20197
                     /gene="aur1M"
     CDS             19247..20197
                     /NRPS_PKS="Domain: PKS_AT (6-296). E-value: 2.9e-64. Score:
                     209.1. Matches aSDomain: nrpspksdomains_aur1M_PKS_AT.1"
                     /codon_start=1
                     /gene="aur1M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PKS_AT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1021:malonyl CoA-acyl carrier protein transacylase
                     (Score: 278.5; E-value: 2e-84)"
                     /gene_kind="biosynthetic-additional"
                     /product="malonyl CoA-acyl carrier protein transacylase"
                     /protein_id="AAX57200.2"
                     /sec_met_domain="PKS_AT (E-value: 1.5e-64, bitscore: 209.1,
                     seeds: 1682, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRTAFVFPGQGSECAGLGRELLALRPDLADTYYRTADDLLGIPL
                     ARICRDGSPRDFEDPAVAQPAVFLTSLAVLEVLRGEGLEPDAVAGHSLGEYAALVAAGV
                     LEWTEALWLVRLRAELVATAGDRIGSATVAVIGPPRSDLVRLCAEARAATGQVVEVAGD
                     NEPRQTVVSGQAAAVERVAREAGAAGARVERLRTGGPFHSSLLGEAAAEFTETLIATEF
                     RDPAVPLVSGVTGGWVTTAAEAAVTLRGQLTSPVRWTEAVATLAGSGVDRYVEVGPGRV
                     LSGLVRRILPGARVHPTCTADRLLGAVDALTAATV"
     CDS_motif       19262..19315
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aur1M_0001"
                     /evalue="1.70E-06"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="aur1M"
                     /protein_end="23"
                     /protein_start="5"
                     /score="20.3"
                     /tool="antismash"
                     /translation="FVFPGQGSECAGLGRELL"
     aSDomain        19265..20134
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_aur1M_PKS_AT.1"
                     /evalue="2.90E-64"
                     /label="aur1M_PKS_AT.1"
                     /locus_tag="aur1M"
                     /protein_end="296"
                     /protein_start="6"
                     /score="209.1"
                     /tool="antismash"
                     /translation="VFPGQGSECAGLGRELLALRPDLADTYYRTADDLLGIPLARICRD
                     GSPRDFEDPAVAQPAVFLTSLAVLEVLRGEGLEPDAVAGHSLGEYAALVAAGVLEWTEA
                     LWLVRLRAELVATAGDRIGSATVAVIGPPRSDLVRLCAEARAATGQVVEVAGDNEPRQT
                     VVSGQAAAVERVAREAGAAGARVERLRTGGPFHSSLLGEAAAEFTETLIATEFRDPAVP
                     LVSGVTGGWVTTAAEAAVTLRGQLTSPVRWTEAVATLAGSGVDRYVEVGPGRVLSGLVR
                     RILPGARVH"
     CDS_motif       19490..19609
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aur1M_0002"
                     /evalue="3.50E-16"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="aur1M"
                     /protein_end="121"
                     /protein_start="81"
                     /score="51.3"
                     /tool="antismash"
                     /translation="GLEPDAVAGHSLGEYAALVAAGVLEWTEALWLVRLRAELV"
     CDS_motif       19760..19798
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aur1M_0003"
                     /evalue="4.70E+01"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="aur1M"
                     /protein_end="184"
                     /protein_start="171"
                     /score="-1.8"
                     /tool="antismash"
                     /translation="SGQAAAVERVARE"
     gene            20228..21790
                     /gene="aur1N"
     CDS             20228..21790
                     /codon_start=1
                     /gene="aur1N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059:acetyl-CoA carboxylase, carboxyl transferase,
                     (Score: 723.2; E-value: 3.1e-219)"
                     /gene_kind="biosynthetic-additional"
                     /product="methylmalonyl-CoA carboxyltransferase"
                     /protein_id="AAX57201.2"
                     /transl_table=11
                     /translation="MQGADDTIHHRIDELTGIKESARSGDEGATGRQHAKGKLTAHERI
                     ALLLDKGSFTEVEPLRRHRASGFGLEAKKPYGDGVVTGWGTVDGRTVFVYAHDFRIFGG
                     ALGEAHATKIHKIMDMAEAAGAPLVSLNDGAGARIQEGVSALAGYGGIFRRNTRASGVI
                     PQISVMLGPCAGGAAYSPALTDFVFMVRETSQMFITGPDVVKAVTGEEITQNGLGGADV
                     HARESGVAHFAYDDEETCIAEVRYLLGLLPSNNRELAPVERSGDPADRPGDALLDLVPV
                     QSGQAYDIRRVIEEVVDDGEHFEVHPGWAPNLVCSLARLDGHVVGIVANNPSAMAGVLD
                     IEASEKGARFVQFCDAFNIPLVTLVDVPGFLPGVDQEHNGIIRRGAKLLYAYCNATVPR
                     ISLVLRKAYGGAYIVMDSRSIGADLALAWPTNEIAVMGAEGAANVVFRREINAAEDPEA
                     VRAQRIAEYKSELMHPYYAAERGLVDDVIDPRDTRPVLIRSLAMLRAKHADLPSRKHGN
                     PPQ"
     gene            21826..22062
                     /gene="aur1X2"
     CDS             21826..22062
                     /codon_start=1
                     /gene="aur1X2"
                     /product="hypothetical protein"
                     /protein_id="ACK77742.1"
                     /transl_table=11
                     /translation="MDAQAPDHLIRVVKGRPDAAELAALTAVVLARAAAHEGRHGGTAG
                     SGPALAGWQRPERLRGFLGPRTWRDRRGEPRSA"
     gene            22150..23163
                     /gene="aur1T"
     CDS             22150..23163
                     /NRPS_PKS="Domain: NAD_binding_4 (4-181). E-value: 9.6e-21.
                     Score: 65.8. Matches aSDomain:
                     nrpspksdomains_aur1T_NAD_binding_4.1"
                     /codon_start=1
                     /gene="aur1T"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score:
                     361.9; E-value: 4.9e-110)"
                     /gene_kind="biosynthetic-additional"
                     /note="essential for forosamine biosynthesis"
                     /product="NDP-D-glucose 4,6-dehydratase"
                     /protein_id="ACK77743.1"
                     /sec_met_domain="NAD_binding_4 (E-value: 5.1e-21, bitscore:
                     65.8, seeds: 102, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 2e-21, bitscore:
                     67.2, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="RmlD_sub_bind (E-value: 5.9e-23, bitscore:
                     72.2, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLLVTGGAGFIGSHFVRTLLDGGYPGHEEDRVTVLDKLTYAGNR
                     ENLPAAHPRLDFVRGDVCDEALLRSLLPGHDAVVHFAAESHVDRSVHSAAEFVRTNVGG
                     TQTLLDACLATGVGRVVHVSTDEVYGSIDEGAWTEERPLLPNSPYAASKASSDLIARAY
                     WRTHGLDVSITRCSNNYGPHQHPEKLIPLFVTNLLEGERVPLYGDGRNVREWLHVDDHC
                     RAIALVLDRGRSGEVYNVGGGNEQTNLHITERLLALCGADASAVRRVADRKGHDLRYAL
                     DETKIREELGYAPRIPFEQGLADTVAWYRDNPGWWKAVKHRTDDLGRKGREGTTTS"
     aSDomain        22162..22692
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_aur1T_NAD_binding_4.1"
                     /evalue="9.60E-21"
                     /label="aur1T_NAD_binding_4.1"
                     /locus_tag="aur1T"
                     /protein_end="181"
                     /protein_start="4"
                     /score="65.8"
                     /tool="antismash"
                     /translation="VTGGAGFIGSHFVRTLLDGGYPGHEEDRVTVLDKLTYAGNRENLP
                     AAHPRLDFVRGDVCDEALLRSLLPGHDAVVHFAAESHVDRSVHSAAEFVRTNVGGTQTL
                     LDACLATGVGRVVHVSTDEVYGSIDEGAWTEERPLLPNSPYAASKASSDLIARAYWRTH
                     GLDVSITRCSNNYG"
     gene            23160..24464
                     /gene="aur1Q"
     CDS             23160..24464
                     /codon_start=1
                     /gene="aur1Q"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056:DegT/DnrJ/EryC1/StrS aminotransferase (Score:
                     376.7; E-value: 2.1e-114)"
                     /gene_kind="biosynthetic-additional"
                     /note="essential for forosamine biosynthesis"
                     /product="NDP-D-glucose 3,4-dehydratase"
                     /protein_id="ACK77744.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 4.8e-104,
                     bitscore: 339.3, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNVHKGLILDETAKFHQDAQDTRPFVPGTTEIWPAGAVLDERDRT
                     ALVEAALEMRIAAGPSSRRFESRFARKLGHRKAHLTNSGSSANLLAMTAFTSHLLEDRR
                     LRPGDEVITVAAGFPTTVNPIIQNGLVPVFVDVELGTYNTTAERVARAIGPKTRAIMIA
                     HALGNPFEVAEIAQLAQEHDLFLIEDNCDAVGSTYDGKLTGTFGDITTVSFYPAHHLTM
                     GEGGCVLTSNLALARIVESLRDWGRDCWCEPGETNKCLKRFNYQMGTLPEGYDHKYIFS
                     HVGYNLKATDIQAALGLTQLDKLDGFCDARRRNWRRLRDGLDGVPYLILPEATPRSDPS
                     WFGFALTVDPEAPYSRAALVDFLEGRKIGTRRLFAGNLTRHPAYIDQPHRIVGDLTNSD
                     VITDQTFWIGVYPALTEEMLDYVISSVKEFVGGHA"
     gene            24461..25858
                     /gene="aur1S"
     CDS             24461..25858
                     /codon_start=1
                     /gene="aur1S"
                     /note="essential for forosamine biosynthesis"
                     /product="NDP-D-glucose 2,3-dehydratase"
                     /protein_id="ACK77745.2"
                     /transl_table=11
                     /translation="MSAPAPARPVPGPRFDADAAERFARSAAVRQGVVRHTDEVHGWLE
                     ERRRAHRFRVERIPFAGLDGWSFDPGSGNLGHRSGKFFTVEGLRVTTSTDGRDRQWHQP
                     IIRQPEVGILGILVKEFDGVPHFLMQAKMEPGNRNLLQLSPTVQATRSNYTKAHRGADV
                     RYVEYFTDPRRGRVLADVLQSEHGSWFLRKSNRNMLVEAVGEVPEHEDFRWLTLGQIGE
                     LLHRDNLVNMDARTVLACAPHADPDGLALHRDTELRSWFTAERSRHDVAADRVPLADLP
                     GWKRTEHSIDHEEGRWFGVVAVAVQAGSREVSGWTQPLFEPVGTGVTAFLTRRIGGVAH
                     LLVHARVEAGFAETVELGPTVQYTPANYAHLPDAERPPFLDLVLGADPARIRYEALHSE
                     EGGRFLNAESRYLFLDVDEDQAPLQAPPGYLWATPGQLTALLRHNHYLNVQARTLLSCL
                     TTGAVRL"
     gene            25858..26823
                     /gene="aur1V"
     CDS             25858..26823
                     /codon_start=1
                     /gene="aur1V"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079:oxidoreductase (Score: 269.1; E-value: 1e-81)"
                     /gene_kind="biosynthetic-additional"
                     /note="essential for forosamine biosynthesis"
                     /product="NDP-D-glucose 3-ketoreductase"
                     /protein_id="AIE41917.1"
                     /transl_table=11
                     /translation="MDPLRIGVLGCADIARRRMLPALRDCPATELVAVASRDAAKARST
                     AAEAGCRAVTGYRALLERPDVDAVYVPLPAALHAEWVEAALRAGKHVLAEKPLTTDLAT
                     TRRLVALAGERGRVLRENVMFVHHSQHAAVRALVADGAIGELRAFHAEFAIPRLPDTDI
                     RHDPALGGGALWDTGVYPVRAALHFLGDRLETEAAVLVRGGPGRAVDTSGTALLRDPSG
                     VCAQLAFGLDHGYRSRYEITGSTGRLTVDRAFTPPAGHPPRVLFERRTGTEEIVLAADD
                     QVLRTVAAFAAAVRTAAAPDGAVLRQAELLDGIRRRARVL"
     gene            26896..27393
                     /gene="aur1X"
     CDS             26896..27393
                     /codon_start=1
                     /gene="aur1X"
                     /product="hypothetical protein"
                     /protein_id="ACK77747.1"
                     /transl_table=11
                     /translation="MPSPHDEIADLREQVRVLRDHAELRELFDRYVCALDTGGPPGRDR
                     ERFASLFTEDVTFAFPIGVCTGIEAFTAFQREAGERWARTHHLSAGHRIDLDGDRATLR
                     VQQITTHVHHITDAAPAHFDVGGYAEARAVRTGAGWRLSHVAFHVVWDSGVRLPELTGV
                     QL"
     gene            27401..27595
                     /gene="aur1W"
     CDS             27401..27595
                     /codon_start=1
                     /gene="aur1W"
                     /product="hypothetical protein"
                     /protein_id="ACK77748.1"
                     /transl_table=11
                     /translation="MNAVQIAGYWVPAREPVREAAPDPLREPAPRAPGHPVPPLTTLLR
                     RRAAWGLAVARGRTVRHHR"
     gene            27623..28528
                     /gene="aur1U"
     CDS             27623..28528
                     /codon_start=1
                     /gene="aur1U"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_kind="biosynthetic-additional"
                     /product="putative acetyltransferase"
                     /protein_id="ACK77749.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.2e-10, bitscore:
                     33.2, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAPPPPATPGIRPVVLDAAGVPLSGLLALPARPVPRAVVVALHG
                     AGMSAGYFDSRARPGLSLLELGASLGYTVLSLDRPGYGASAAALPEGQELAGQTETLLA
                     ALEDFARGHELGAGYFLVAHSNGGRLALSAAGAGDGFAPLGVDLSGLGRRFAVELGQLP
                     GTTADLRSQWRRHWGALRFYPPDAFRQGAELIRPVPVLEARETMRWPDAYPAIAARVGV
                     PVRFTFAEQELWWRTDGGALEELLSPLSGAPVEAVRQPDSGHNISLGWAARTYHLRVLA
                     FLEERLLARDAALTAPVATP"
ORIGIN
        1 gtggacatcg atgtactggg cgcactgacc gtgcgggaga acggggtctc catcacgccg
       61 accgccgcca agccccgtca ggtgctggcc ctgctcgcgc tccacgcgga ccaggtggtc
      121 ccggtgtccg cgctgatcga ggaactgtgg ggcgagcagc ccccgcgcag tgcccgtacg
      181 accctgcaga cctacgtgct ccagctgcgc gggctgatcg ccaccgcact ggagggcacg
      241 gacgggacgc gcacccccaa ggacgtgctc gtcacgctgc cgggcggcta catgctcagc
      301 agcgccggcg ggaccagcga cgtccgcgaa ttcgaccggc tggccggaat gggctaccgg
      361 gcgatggacg cgggcgactt ccccggtgcc gcgcggctgc tgcgcgaggc gctggcgctc
      421 tggtccgggc cggccttcgc cgacgtggag ggcggtgtcc agctggacat ggagacgcgg
      481 cgcctggagg agacccggct gtgcgcgctc gaccagcgca tcgaggccga cctgcgcctg
      541 ggccggcacc gcgaactgct cgcggaactg accgtcctgg ccagccgcta ccgcatccac
      601 gagaacctgc acgggcagtt catgctcgcc ctccaccgct ccggacgccg cggcgaggcg
      661 ctcagcgtct accagcggct gcgcgccacc ctcgtccgcg agctcggcat cgagccgtcc
      721 tcggccctgc gcagtctcca gcggtcgatc ctgatgagcg gcccggagaa cccggcggaa
      781 tccccggaga cggcccgcaa gcggctcgcc cgagtgggct gacggatcat taaaagatca
      841 ttcgcccact gctttccggt atctcccgga aatccgtgga ccgaatttgc gcatcaggca
      901 agcggaacag cggcgaccga actgatctac gggctgaaca ggggttctgg cagtcaatcg
      961 gaaggcgggg tttcgaatcc cgcggccgtt cgcccccttc ggaggtctgc tcgacgtcgg
     1021 cttgagaacg cggtgatgcc gccctgggct gccttaccgt catcgggtcg aatactgaaa
     1081 accgtgagta tctcgacgaa ataacggagg ggagacggga gaccgtggag attcaggttc
     1141 tgggtccgtt gagtgccgag gtcaacgggg catcgatcgt tcctacggcg ggcaagccgc
     1201 gtcagatcct ggcgctcctc gcgctctacc cgggccgggt gatgcccgta ccgaccctga
     1261 tggaggagat ctgggggacc aagctcccgg agagcgccct caccaccctg cagacgtaca
     1321 tcctgcagct gcgccgcaga ctgggcaccg cgctggggcc gggcgccccc ggcacggcca
     1381 aggacgtgct cgcgacccgg cacggaggct acctgctcca gatcccgcag gagtcggtgg
     1441 acgtccacgc gtacgaggcc ctggtggccg gcggccagat cgccttcgac gagggcgacg
     1501 acgaacgcgc ggcgagcatg ctgcgcaagg ccctcgacct gtggcagggg cccgccctcg
     1561 tcgacgtcaa ggtcgggccg atcctggaga tcgaggtgct gcggctggcg gagagccggc
     1621 tggtcaccac cgagcggcgc atcgacgtgg acctgcgcct gggacggcac agcgaactcc
     1681 tcgccgagct caccgagctg atggccagga acccgcagca cgagggcctg cactcgcagg
     1741 cgatggtcgc gctgtaccgg tcgggacggc aggccaccgc gctggacgtg taccgcaggc
     1801 tccgggcccg gctgatcggc gaactgggcg tggaaccctc gcagcagctc cagcgcctgc
     1861 accaggcgat gctccgggtg gacccggcgc tcgacgtggt cgcgggcccg cgccgcagct
     1921 cgaccttcga cctctacgcg gcctgacgcc aaggctccag cgcggctggc cgacggcgtg
     1981 agcgactctc catccggtgg gaccaggctc gtcgcgaccc ggtgtgcgcc gatgccccgg
     2041 cggacgagga gagaggcaag ccatggaccg gctggagctc acggagctgg cccgcatcct
     2101 gcggatctgg ggaggcgaag acgactgcgt cgagctgagc gaggacgtcc aggacctgta
     2161 ctggatcgag ctcggctacg acagcctctc cctcctgcag gcaaccggct ccatcgagcg
     2221 caagtacgac gtgctcctcg acggtgagct gctcgaactg gcggacaccc cgaggagctt
     2281 cctgcggtgc gtcaaccagg tcctgcgcgg ccgggccacc gccgcggtgt gatcccgggt
     2341 gccggccgcg tgcggaaatc gagcggcatt cgaaggggac tccggcggat acagacagac
     2401 tctgcgtcaa gcgttgagag aggtgtctga tgtctgtcga gcgagtacac cggatgtcac
     2461 acgcggtcga cgcggccgca ccggccgggg tcctgtacaa cgtggtggcc gacacggcgc
     2521 cgtggccgct gttcctgccg gacacggtgc acgtggagag acttgactcc accgggacca
     2581 cggaccggtt ctcccagtgg gcggacacgg acgggcgccc gcggccgacg ctgtggcgcc
     2641 ggaccctgga cgcgcaccgg cgccggatcg acttccggcg ggagcggccg gccgaccccg
     2701 tcaccacgca agggggttcc tggagcgtgg aggaactggc cccgggctgg tcacggctga
     2761 cgctggagca ggacatcacc gtcgccggca accggagcgc cgacgtggag cgggtgctcg
     2821 cgtccgcgcg cgacggtgcg aggtccgtgc tcggccggct gggcgccgtc gccgaacgct
     2881 ggcggcggct cgacgggctg ctgctgtcct tcgaggactc ggtgcggatc ccgggaccgg
     2941 gcgaaccggt ccacgagttc ctctaccgcg tggggtcctg gcccggccgg gtggcgcacg
     3001 tggtgggcgc ggaggtcacc gaggtgagcg ccggggtgca gcgcaccagc atggtcaacc
     3061 tggccgacga cggctccgcg tacaccacgg aggaggtgcg ggtgtgcttc ccggcggccg
     3121 gccgcatcgt cttcaagcgc acccggccgc accccctgct ggccgcgcac gccggggagt
     3181 ggtccgtgga gcctgacgcc acgggggtca ccgtggtgtg ccggcacgac gtgctgctgg
     3241 acgcgggcgc ggtcgagcgg atgctgggac cgggcgcgga tcccgcgcgg gcgggccggc
     3301 acgtgcggga ggtgctgggc cgggagagcc gggccaccct ggagcccgcg cagcagtacg
     3361 cccgggagtc ggtcaggagc ctgcggccgg tgtgagcggg ccgggcggcc gtccgtgccc
     3421 gaccgtggcc gtccgtgccc gaccgtggcc gtccgtgccc gaccgtggcc gtccgtgccc
     3481 gactgtggcc gtccggccgt ccggccggcc gtccggccgt ccggccgacc ggccgaggcc
     3541 gctcgcccgg ccgggtgtgt gggcggaaag gaccgggccc ctggcccgta cccccgatcg
     3601 cggggtgcgg gccgggggcc cggtcctttc gtcgtcgtgg cggcccgtgg ccgccgtggc
     3661 gggggccgcc ccggcgcgtc aggagccgcg gcccgcagcg cccagggagc gcagggtggc
     3721 cggggctgcc agacagggca tgaccacccg ccagaacccc gccagcgtgc gcggggcgag
     3781 ccactggggg tcgtcccggc cgagcacctc gaagccgagc gtggcggcca ccaccgtcgt
     3841 ggcgacgctc tggcggttga ggccgggcag cagggcgtcc tcgtgcgccg cctccgccag
     3901 cagccggtgg acgtactcgt gccattcccc gggcagggcg tacgacgacg ggtaggtggg
     3961 ctcccggctg agctggaacc cggcccgtgc caccgtgtcg gacaggagca gcccggcgag
     4021 ggcgtgggag ctgtccgcca gggcctggag ggccgaggtg cgccgcgcgt acacctcccg
     4081 ggccgccgaa cgcagcgctc gcgcggcggc cgcctcgacg gccgccgcga ccgcggcctt
     4141 gttctcgaag tggaagtgca gcgcgcccgg gctgactccg gctccgacgc tgatcatgct
     4201 cagcgtcgcc tctgcgtacc cgcgccgtcc gaacaccctg gccgccgatt cgatcagtgc
     4261 gcggcgggtg cggacagcgc gttcttgttt gatcacgcat agctcctgta tcagtttcct
     4321 tctattatta aaccgtcccg ttggtattgg aagcaggtgt gggtccccct ggatggcctg
     4381 ttctgcgtgg ttattcgcct gtcgatggcc cgatttaacc cttttatcgg caacacggct
     4441 ccgttttgtg ggctttgaca aaccgacgca gcggtttgta tcttcttgac gttgacccaa
     4501 ccgagcatga gggagggggg cagatgaacc agcggaccat ggctgtgctg gaacctcaca
     4561 cagtcgccgc gggagcgaac ggcggtttct caccggccga aggcccgaga acaccgcagc
     4621 acgtgccggc gcagtcggcg ctgtggcgga tcctcatcgt ggagagcaat tcggccgagg
     4681 ccgagacgct ggcgcgcggt ctgcgccggc acgggcacga ggtcgacatc gtgggcaccg
     4741 gcggcgaggc gctgcgcgtc tacgccgaag ccgacctggt cctcctcgac ctggaactgc
     4801 ccgacctgga cgggctggag gtctgccggg gcatccgcgc ggcccacgag atacccgtca
     4861 tcgcggtcac cgcccggggc agcgagctcg accgggtcct cggtctccag gcgggggcgg
     4921 acgactacct ggccaagccc tacgggttcc gcgaactcat ggcgcgcatg gaggcggtca
     4981 tgcgccgcgc gcgcccgacc cgccccgcct ccgccaccat cacctgcggg ccactgtcca
     5041 tcgactccgg gacgcgcgag gtgacgctcg acggggtgcc cgtcgagacc acccgcaagg
     5101 agttcgacat gctctatctc ctcgcgtccc atcccgacac cgtcatcccc cgcaagatgc
     5161 tgatgcagca ggtgtggggc gactcctggt cccgccggac cgtggacacg cacgtcagca
     5221 ccctgcgcaa caagatcggc gccggctgga tcatcaccat ccgcggcgtc ggattccgct
     5281 tcggccaggg ctgagcccgg ccggacccca ccccaccgca ccgaccaccg accagcgacc
     5341 acagacacga gccgaggggg aacgacatga cggtgaccgc gctgtgccac ggggagagct
     5401 gccggggcgc ggacgccacc ggacgcaccc ggcggcgggc cgcggaccgg ggcagccggc
     5461 tgtgccgccc ctgccgcgag cacctcgcgg cgggcctcgg cgaagtcgcc cacctctacg
     5521 aggaatgcgg acgcgtgctc ggcggcgcgg gccccggcag cctgcgcgag cggaccaccg
     5581 gtggcgagtc gaccgggctc cccttcaacg gggccgccgc ggacgtacgg gccaggatgg
     5641 tctccgtact gggatcctgg agcggcctgg tcgcacagca gcgcggtctc accgcaccgc
     5701 cgcgcaccgt cgccgacctc accgccttcc tgctgcgcaa cgccgactgg ctcgccgccc
     5761 acccggcggc cggcgaggtc tgcgacgagg tcgcccgcct ggtccgggcc ggacgccgcg
     5821 cggccttccc cgaaccggcc cgcaccttcc gcctcggcac ctgccccgag cccggctgct
     5881 ccggcgccct cgccctgtcc gtgcgcggcg cggagcggga cgccgaccgg gcggtcgtgt
     5941 gcgacgccga cccggcccac cgctggacca gcgaccggtg gagcgagctc agcgactccc
     6001 tggagtccgg gcgggcgccc ggcgccgccg cggccccggc cccggccccg gccccggccc
     6061 cggccccggc caccgaacgc tggctcaccg cggccgacat cgcacagctg tggcacaccc
     6121 cgacgggcac cgtgtaccgg ctggccagcg aggagcggtg gcgccgccgc aaccgcgcgg
     6181 ggcgcacctt ctacgccgag ggcgacgtcc gcgcctgctt cgcccgcagg gcgcaggccc
     6241 gcgcctgagc cgcccccgcg ccaccggtga tccgccggtg gcgcaccggt cttccgcacg
     6301 acgttccccg gggacccgca cagcaaccgg tagggcccgg atggagcagt ctgacgtggc
     6361 cttgacactc ccttggccgt tctccgaccc agcggagaat cccttgtgga acctgacgga
     6421 gtcctgaatc cagcgccatt gaacggccgc tcgcgtccga agaaccttgt agtcaagatc
     6481 cggtgcactg tctccggagg cgaattcaag gagacgcgat ggacgcccca gtgatcgtcg
     6541 tcggcgcggg ccccgcgggc atgatgctcg cgggcgaact gcggctggcg ggtgtcgccg
     6601 tcatcgtcct cgaacgtctg gagcggcgta cgggcgaatc gcgcggcctc ggcttcaccg
     6661 cgcgcacgct ggagaccttc gaccagcgcg gcatcctcgc gcgcttcggc gacatcgagc
     6721 gcagcacgct gggccacttc ggcggcctgc ccctcgactt cggcgtgctc gacggagcct
     6781 gccaggcggc caagaccgtt ccgcagtccg tcaccgagac ccacctggag gaatgggcca
     6841 cgggcctggg cgccgacgtc cggcgcggcc acgaggtcct ctcggtgcac gacgacggcg
     6901 acacggtcgc ggtcgaggtg cgcggtccgg gcgggacgca caccctgcgc gccgactggc
     6961 tggtcggctg cgacggcggg cgcagcaccg tgcgcaaggc ggccggcttc gacttccccg
     7021 gcacggccgc caccatggag atgttcctcg ccgacatcaa gggcatcgaa ctcaagcccc
     7081 gcatgatcgg cgagacgctg cccggcggga tggtgatggt cggtccgctg cccggtggca
     7141 ccacccgcat cgtcgtctgc gaacggggca ccccgccgcg gcggcgcgag gccccgccgt
     7201 ccttcgagga ggtcgccgcc gcctggcagc ggctgaccgg cgaggacatc tcggccgccg
     7261 agccggtgtg ggtgagcgcc ttcggggacg cggcccggca ggtcaccgag taccggcgcg
     7321 gccgcgtact gctggcgggc gacgccgcgc acatccacct gcccgcgggc gggcagggca
     7381 tgaacaccgg catccaggac gcggtcaacc tcggctggaa gctcgcctcc gtggtcctcg
     7441 gccgggcgcc gctcgccctg ctcgacacct accacgggga gcggcacccg gtcggccggc
     7501 ggctgctgat gaacacccgc gcccaggggc tgctgttcct gagcggcgcc gaggtgcagc
     7561 cgctgcgcga ctccctgcgc gagctcatgg cgtacgagga cgtcgcccgc cacctcgcgg
     7621 ccatggtgac cggactggag atcacctacg acgtcggcaa gggcggccac ccgctgctcg
     7681 gccgccggat gcccggactg gaactggccg ggcccggcgg gcggacctcc gccgccgcgc
     7741 tgctgtgccc cgcccggggc gtcctgctgg acctggccga caacccccgg ctgcgccagc
     7801 gcgccgccgc ctggggcgac cgggtggaca ccgtcaccgc ccgccccgcc ggagcggccg
     7861 ggggcgagct gccggacgac accaccgccc tgctgatccg gcccgacggg tacgtggcct
     7921 gggccgcgcc cggcagccac cacgacctgc cgatggccct ggagcgctgg ttcggccccg
     7981 cctgaggccg ggccccgccc ggggccggtc cggcccgggt cgccccgagt accgcgcgtc
     8041 cggcggccac cgcgccggcc gggggcgggg cgcgtccgcc cgccccggca cgcccccgta
     8101 cgagcacctc aagagcaccg cacgcgcatc cccgagcacc tcacgaggag acaccaccca
     8161 tggcaacgcc cctggcaacc atcgagcgcg ccccgtccgg accggccggg gagcgccgtg
     8221 agatcgtccg ggccgcccgt acggtcctgg cccgcgaggg ctggacgcgc tgcaccgccg
     8281 aggccaccgc ggcggaggcg ggcgtaacgg ccgacaccgt cgcgctgcac ttccccgacc
     8341 acgagcagct gctgctgggc gtgctgctgg acagttccgc ttccgtggcg gcggccctcg
     8401 cggccgtcgc cgacagccac ctcgaagagg tcaccgacct ggaagcggac ctcatcgccc
     8461 tcggccgggc ctggctcgca ccgctggagg ccttccgcga gcacttcgcc atcgtccggc
     8521 acatcagcgc cgaggtcacc cggctgccga ccgaggccgt cgacaagtgg caggccaccg
     8581 gtccccgcca ggcacgtcgt gaactggccc gcaggctccg gcgcctggcc tccatgggcc
     8641 tgctggacat ctccgacgcg gagcaggcgg cggaacgttt catcctgctg gtcccctccg
     8701 gggtggtgca gcgctccttc ctgggcgcgc tgccgctgcc ccgggacgag gccgacgcgc
     8761 tcatcgccga cggggtggcg gacttcatcc gcctctaccg gccctgacac cacccgcgga
     8821 cttctgcgct ccggtaccgc cggagcacct cgcccccgaa catccccacc gcacggaaag
     8881 agacctcgga tgacgcacag caacctcatc gtggcccgga tggacagcat gtcgagcgac
     8941 caagtcgcca agctgttcac cgagttcgac aagacggaca tgccgggacg gatggggacc
     9001 ctgcgccgcc gcctcttcat gtacaagggc ctctacttcc acctccagga cttcgcggag
     9061 gacgacggcg gccagcggat ccaggagtcc cgcaccgacc cgcgcttcat gcggatcagc
     9121 cacgacctgc tgcccttcat ccagccgtac gaccccgcca cctggcgcac cccggccgac
     9181 gccatggcca cgcgcttcta cgactggtcg gcctcggaat gagagccgtc cgggccaaca
     9241 cgaggggagg gccgtaccgg tgacccgtcg ggtagtgatc acggggatcg gagtgctggc
     9301 gccgggtggc atcggcacca ccgccttctg gaacctgctg agttcgggcc gcacggccac
     9361 ccgcgggatc accctcttcg atcccgcccc cttccgctcc cgggtggccg cggaggtgga
     9421 cttccacccc gaacggcacg ggctgacctc cctggaggtc cgccgcatgg accgcgccgc
     9481 ccagttcggt gtggtcgcca cccgtgaggc gctcgccgac agcggcctcg acctcgcggc
     9541 attcgacccg taccgcatcg gcatcgccat gggcaccggt gtcggggcca tcagcggcct
     9601 cgacaccgcc taccgggtgg ccagcgacga gggacggatc gcccaggtcg accacatgta
     9661 cgcgccgggc cacctctacg accacttcgt gcccagctcc ttcgccaccg aagtagcctg
     9721 ggccgtcggc gccgagggcc cctccacggt ggtctccacc ggctgcacct ccggcatcga
     9781 ctcggtcgcg cacgcggtcg acctgatccg cgagggcagt gccgacatca tgatcacggg
     9841 cgccaccgac gccccgatca gcccgctcac cctggcctgc ttcgacgcga tcaaggcgac
     9901 gacggcgctc aacgaggaac cggagacggc ctcgcgcccc ttcgacgcca cccgcaaggg
     9961 cttcgtcctg ggcgagggcg cggcggcgtt cgtcctggag gagctcggcg ccgcccgccg
    10021 ccgcggcgca cacgtctacg cggagatcgc cggctacgcc tcccgctcca gcgccttcca
    10081 catgacgggt ctgcgccccg acggccggga gatggccgag gccatcacgg tggccctgga
    10141 cgaggcccgg ctggaccccg gcgacctcga ctacgtcaac gcacacggct ccggcacccg
    10201 gcagaacgac ctccacgaga ccgccgcgta caagctggcc ctgggcccgc acgcccaccg
    10261 gacccccgtg agctcggtca aatcgatgat cgggcactcg ctgggatccg tcggctcgat
    10321 ggagatcgcc gcctccgtcc tcgcgatgga gcaccacgtg gtgccgccca cggccaacct
    10381 gcgcaccccc gacccggagt gcgacctcga ctacgtaccg ctcgtcgcgc gggaccaccg
    10441 caccgatgcc gtcctcaccg tcagcagcgg attcggcggg ttccagagcg cgatggtgct
    10501 ggccaggccc gacaggagga ccgcatgagc gcgaggatcc tggtcaccgg catcggtgtg
    10561 gccgccccca gcgggctcgg cgtggaggac ttctggtcgg tcacccgcat cggcaagaac
    10621 gccatcggac ccgtgacccg cttcgacgcc tccgcctacc cctcccggct ggcgggcgag
    10681 atccacggct tcgagcccaa ggaacacctg ccgggccggc tcgtcccgca gacggaccgg
    10741 gtcacccagc tcgccctcgt cgccgccgac tgcgccttcg ccgacgccgg gatcgaaccg
    10801 ggcacgatcg acccgtacgc gatgggcgtg gtcaccgcgg ccggcgccgg ggggttcgag
    10861 ttcgccgaga acgagctgcg caagctctgg agcgagggcg ccaagcacgt cagcgcgtac
    10921 cagtccttcg cctggttcta cgccgtcaac agcggccaga tctccatccg caacgggctg
    10981 cgcgggccgg ccggggtggt catcagcgac caggccggcg gcctcgacgc cctcgcccag
    11041 gcccgccgcc agctccgcaa gggcagcaag ctgatcgcca ccggagggtt cgacgccccg
    11101 atctgctccc tgggctgggc ctcgcacctg cacggcggcc tcatgtccac gagcgacgaa
    11161 cccgagcgcg cctacctgcc cttcgacgac gccgccgccg gctacgtccc gggcgagggc
    11221 ggggccatgc tcatcctgga ggacgaggac agcgcccggg accgtggcgc gcgtaccgtc
    11281 tacggggagt tcgccggata cggggccacg ctcgacccca agccgggcag cggacgggag
    11341 ccgggcctgc gccgggccat cgacgtggcg ctcacggacg cggcgtgcca tccggccgag
    11401 gtcgacgtgg tcttcgccga cggcgcggcc accccgcgcc tcgaccgcga ggaggccgag
    11461 gccatcaccg cggtcttcgg cccgcgcgcg gtcccggtca ccgtccccaa gacgatgacc
    11521 gggcggatca actccggcgg ggcgccgatc gacgtcgtct cggcggtcct ctccatgcgg
    11581 gagggcctga tcccgccgac caccaatgtg gagctgtccg acgcgtacga cctcgacctg
    11641 gtggccgtac ggccgcgcac ggcctcggtc cgcaccgcgt tggtcctcgc ccgcggccgc
    11701 ggcggcttca actccgcggt cgtggtgcgc gccgtcgact gacggccccc cgagccggcg
    11761 tccgcccacc gtcgttcccc ctgacggagg cgggcgttgt gtgtgaccgc agccgagatc
    11821 ccccgggtgc ggaagaccga tgaagggatc cattttgtcc aagcaggaat tcaccttcga
    11881 cgacctcaag cgcatcctcc tggagggcgc gggcgcggac gagggcgtcg acctcgacgg
    11941 cgacatcctc gacagcgagt tcgagacgct gggttacgag tccctggcac tgctggagac
    12001 cggtgggcgc atcgagcgcg agttcggcat cacgctcgac gacgacgtct tcaccgacaa
    12061 cccgacgccc cggtccctgg tcacggccat caacgagagc ctgagcgcgc tggtcgacgc
    12121 ctaggaccct ctcgtctgcg ggcggccgcc gcatcggagc ggcggccgcc ggcattccca
    12181 gcactccccc ccttcttatc catggagaac ggacacatgt cggatcagga caagcgggtc
    12241 gccgtcgtca ccggtgccac cagcggaatc gggctggccg tggcgcggct gctggcggcg
    12301 caggaccacc gggtcttcat cggcgcccgc agcgccgaga acgtggcgca gaccgtcaag
    12361 gagctccagg acgagggtct ggaggtcgac ggagcggtgg tcgacgtccg ctccaccgac
    12421 ggggtacggg cctggatcca ggccgcggtg gaccgtttcg gcagcgtgga cgtggtcgtg
    12481 aacaacgcgg ggcgttcggg tggcggtgtg acggccgaca tcgccgagga gctgtggcac
    12541 gacgtgatcg acacgaacct caacagtgtc ttccgtgtca cgcgtgaggc gctgaccacg
    12601 ggcgggctgc gggcgaagga ccgcggccgg atcatcaaca tcgcgtccac ggccgggaag
    12661 cagggcgtgg tgctgggcgc cccgtactcc gcttccaagc acggggtggt gggcttcacg
    12721 aaggcgctcg gcaacgagct ggcccccacc ggtatcaccg tgaacgccgt ctgcccgggt
    12781 tatgtggaga cgccgatggc gcagcgcgtg cggcagggtt acgcggccgc ctatgacgcg
    12841 acggaggagg cgatcctgga gaagttccag gcgaagatcc ccctcggccg ttactcgacg
    12901 ccggaggaag tggccggcct ggtgggttac ctggcttccg acgccgccgc ctccatcacc
    12961 ttgcaggcgc tgaacgtctg cggcggcctc ggcaacttct gaccgtgctc gtttcgactg
    13021 ttgaggagtc atcggcatga cgcagcccgg tctgcgcgag gtggagcacg agatcacggt
    13081 ctcggctccg gccgccgccg tctaccgtct gatcgccgag gtcgtgaact ggccccggat
    13141 cttccccccg acgatctacg tcgaccaggt gccggagggg cccggcgagg agcggatccg
    13201 gatctgggcg accgcgaacg gcgaggcgaa gaactggacc tcgcgccgca ccctggacgc
    13261 ggaggcgttg aggatcacct tccgccagga ggtcaccgcg ccgccggtgg ccgcgatggg
    13321 cgggacctgg atcatcgagg agctgtccgc gcaggagtcg cgggtgcggc tgctgcacga
    13381 ctaccgggcc gtcgacgacg acgcggactc gctggcgtgg atcgacgagg ccgtcgaccg
    13441 caactcgcgt tcggagcttg cggcgctgaa gaagaacgtc gaggcggcgc acgcggccga
    13501 agagctgacg ttctccttcg aggacaccgt gcagatcgag ggctcggcga aggacgtgta
    13561 cgacttcgtg aacgaggcgg accgctggca cgagcggctg ccgcacgtgg ccacggtccg
    13621 tctgcgcgag gacacccccg ggctgcagga gctggagatg gacacccgcg ccaaggacgg
    13681 ctcggtgcac accaccaagt cctaccgggt gacgttcgcg caccaccgga tcgcgtacaa
    13741 gcagacgacc ctgccggcgc tgatgaccct gcacaccggt tactggacgt tcgaggagaa
    13801 cgagggcggg gtggcggcct cctcgcagca cacggtgacg atcaacaccg acaacatcgc
    13861 ccggatcctg ggcgagtcgg ccacggtcga gaccgcgaaa cgctacgtcc acaccgccct
    13921 cagcaccaac agcaccgcca ccctccacca cgccaaggcc tacgccgagg gcatcgcccg
    13981 gggcgggaag aaggactgac catgagcggg gactacagcg aaacccaggt gatcgtggtc
    14041 ggtgcgggtc ccgtcgggct gctgctcgcc ggagaactgc ggctggcggg cacggacgtg
    14101 gtggtcctcg acaagctcac cgcgccgacc accgaatcgc gggcgtccac cctgcactcc
    14161 cgcaccatgg agatcctgga cacccgcggc ctgctcgacg gcctgggcga catcccgaac
    14221 gacccctccg gccacttcgg ggggatcccc ttcgacctgg ccctccccgg cccctacccg
    14281 ggccagtgga aggtcgccca gacccgcctg gaggaagtgc tgggccagtg ggcggcggac
    14341 ctgggcgcgg acatccggcg cggccacgag ctgacgtcgc tgaccgagac cggggacctg
    14401 gtcaccgcgg aggcgcgcgg cccggacggc acggtctcca ccgtccgggc cgcgtacgcg
    14461 gtcggctgcg acggcgagca cagcgccgtg cgccggctgg gcggcttcga gttccccggt
    14521 accggggccg agcgcgaact gctgcgcgcc gacgtggcgg gcatcgacat ccccggccgc
    14581 cgcttcgagc ggctggaggg cggactcgcc atcgccgccc ggcgccccga cggggtgacc
    14641 cgggtgatgg tgcacgagtt cggggcccgg ccccggcccg gagcgccctc cttcgaggag
    14701 gtggccgaca cctggaagcg catcacgggc gaggacatcg ggggcggcac ccccctgtgg
    14761 gtcaactcct tcggggacgc ctcccggcag gccgcgagct accgcaaggg ccgcctcctg
    14821 ctcgccgggg acgcggcgca ccagcagatg ccgatcggcg gccaggccct caacctcggt
    14881 ctccaggacg ccttcaacct cggctggaag ctggccgccg tggtgtccgg gcacggcggc
    14941 gaggcgctcc tcgacagcta ccacgaggaa cggcacgccg tgggccgggc cgtgcaggcc
    15001 aacatccgca cccaggcgct gctcctcctc ggcggacccg aggtcgacgc gatccgggag
    15061 gtgttcgcgg aactgaccgg ccacgaggac gtacgcaccc acctggccgg gatgatcacc
    15121 ggcctggacg tccgccacgg cgccggctcc caggaccccg cggcgggcct gcgggtcccg
    15181 caggccgggg cggtgggcga agagggcggc accaccgtct tcgagctgct gcggccgggc
    15241 cggggactgc tgctgctcgc cccgggcgac gaggcacgcc gcgaggaact gcgggccgcc
    15301 gccgcgccct ggcgggaccg cgtacggatc gccacggcgg ccggagcgga cggggaggcg
    15361 ggccccgcgg ccctcctggt gcgtcccgac ggccacgtcg cctggtcgga cgggacgccg
    15421 gacacggcgc ccggcgagga cctgacggcc gccctggaac ggtggttcgg gccggccgcg
    15481 ctgcgtcccc cgcgccaggc cgccccgcgc gaggcggtgc gggtcacccc ggtgacggcg
    15541 gcccgggagg tccggggcgg cggcacggac cggctcgccg gccggaccgc gctggtcacc
    15601 ggatcgagcc ggggcatggg ccgcgcggcg gcgatcaggc tggcggagga gggcgcgctc
    15661 gtcgccgtcc actacaccag tgacggggcg gccgccgaag aggtcgtcgc ctcggtcgag
    15721 aaggacggcg ggcgggcctt cgccatccgg gccgaactcg gcgtccccgg agacgtggag
    15781 agcctgttcg gcgccctgga agcggacctg ctggagcgca ccggcagcac cgacctgcac
    15841 atcctggtga acaacgccgg ggtgatgggg ggcgtcggcc cggccgacat cacccccgac
    15901 cagttcgacc ggatcttcgc ggtcaacgcg aaggcgccgt ttttcctgat ccagcgggcg
    15961 ctgcggaaca tgcccgacgg cggccggatc atcaacatct cctccggcct gacccgcttc
    16021 gccaacccgg acgagatcgc ctacgcgatg agcaaggggg cgctcgaaca gctcgccctg
    16081 cactacgcga aggcgctggg cccccggggc atcaccatca actccgtcgc gcccggcatc
    16141 acccgcaacg gcaaccccgt cttcgacatc cccgaagcgg tcgagcagat ggcctcgctg
    16201 tccgccttca accgggtggg cgaaccggag gacgtcgccg acgtggtggc gttcctcgcc
    16261 accgacgagg cccggtggat caccggttcc ttcgtcgacg ccacgggcgg cacgctcctc
    16321 ggctgagccc tcgtccgccc gctctggact cgccggcgct accccgcgcc cgccggcgac
    16381 ggggtgggcc gtacgggaac cctcccgtgc ggcccacccc tcttcgcttc ccgtcccccg
    16441 gtccccgatc cctcctgcga gcgaaacacg agcatgtacc cctcgacgac aaacccgccc
    16501 gtcggtgagc ggacgcgctg ggccctggtg gccgtactgg ccgcgaacat gctggtcgac
    16561 gcgctggagg tgtccgcgac cctggtggcg atgccggccg tcggggccga cctcggggcc
    16621 ggcgccgccg ggctccagtg gctcgtcagc ggtttcgccg ccggattcgg cgggctgctg
    16681 ctcctgggcg gccggctggt cgaaggcctc ggccgccgca gggtcttcct ggccgcgctg
    16741 ctggtcttcg ccgccgcctc gctggccggg gcgctgacgg acagcctggc ggcgctgacc
    16801 gccacccggg tgctgaaggg cttctgcgtg gcgctgaccg cgcccaccgg actggccatc
    16861 atcacctcgg ccgttcccga gggcgcggcc cggcgccggg cggtgtccct ctactccctc
    16921 ttcggcgccg ccggcttctg cgcgggcctg ctgctgtccg gtctgttcac cggggcgggc
    16981 tggcgctgga ccctggcctt cccggcgccc gtcgccctgc tgctgctggc cgccggggcg
    17041 cggctcgtcc cgcgcgacgt ccgcgacagc ggtgcccgcg acgcaggtgt ccgcgacgca
    17101 ggtgtccgcg gcgcaggtgt ccgcggcgca ggtgtccggg gcggcggtct ccgcggcccc
    17161 ggacggcacg ccgcggcctg cggcgccgcc ctgaccggag ccgtcctgct gctcgtgtac
    17221 gggctcgcac acctggcggg ccccggccgc gaaccggtcc gggcggcggc cgcgttcgcc
    17281 ggggcggcgc tgctcggggc cgtgttcgtc acggccgaac ggcgctcgcc ccggccgctg
    17341 gtgccccccg tactgctgcg gcacgggccg ctgctgcgct ccgcgctcgg cgccgccgcg
    17401 ctcaacggct cgtacgtggg cttcctgctc gtggcctccc tgcacctgcg ggagaccggc
    17461 cggagcccct ggcagaccgc cctcgtcttc ctgccggcgg cggcgccgct cgcgctgagc
    17521 gcactgcact cggcccggat cgccgtccgc ctgggcccgg cgcgggcggt ggccgccgga
    17581 gccgtcctcg ccccgctcgg ctacgcgctc tacccgcggg ccccggacgc cgacccccga
    17641 tggaccgtac tgctgcccgc gacggcctgt gtcggggccg cgttcgccct cgccttcacc
    17701 gccctgcacc ttcaggcgac gggcgcggtc ccggcccggc tccagggcgc ggccggcggg
    17761 ctctaccaga ccttcgtcca ggcgggcgcc gcactgacgg cggcgcccgt ggccgccctg
    17821 tacaccgtgg gccgcgctcc ggcgctctgc ctggtcaccg tcatcggcgc ggccggcgcc
    17881 tgcgtcgccc tcggcggcct ggtcccggcc gcccgtgccg cggcggcgcc accaccgaac
    17941 catccgtgaa tccccccccg accacgggcg gacggggagc aaccgacccg tccgccccga
    18001 ccccggaaag cagcatgaac acacttcaca tgtcacagac gtacgaaaca gacaacggcc
    18061 tggtccacat gaccccgccc gacatggcgg tgctgaacgc ggtcggactg cccgagcgca
    18121 cccggatcct ggagcagtac gtccgcgagg agctcggccg catcctcggg atcgagccgt
    18181 ggatggtgga caccacgggc cgccccatgg gctgcctggg catcggatcc atctccggaa
    18241 tcgaactgca gtaccggatg gagaacacgc tcggcgtcga cgtgaacctc cagcggctgc
    18301 tgctggccaa cagcgcgcag gagctcatcg actgcctcgc cggtcagttc ggccccgagg
    18361 cccacctgca cggggcaccg gtgccggcat gacggccacc acgctcctcc ccgccgcgcg
    18421 tccggtcgtc caccaccagg acctcgatcg cgcggacttc accctctccg ccgaccgcgt
    18481 cgacctctgg ctgatccgcc gccccaccgg cgcggacgcc gaggccctcg cgatcgagga
    18541 gctcgacgag tcggagcgca agcgcaccga ctccttcatc cgccggacgg acggcatgct
    18601 ctacgccgcc gcccacgtgg cggtgcgccg actgctcgga cggtacacgg ccacccgccc
    18661 cgaggacgtg cgcttcatgc gggagccctg ccccggatgc ggcgagccgc acggccggcc
    18721 cgcgctctcg cccccgccgc cgcccttgca ctactccctc tcgcacagcg ggggagtagc
    18781 catgatcggc gtcggcaccg tgcccctggg cgtcgacgtg gagaaactcc ccggagccga
    18841 gaccgtggac atctgctcga aggcgctcca cccgcaggag cagctggaga tagccgaggc
    18901 cgaggagggc gaggagcgcc gccagctgtt cgggcagacc tggacgcgca aggaagcgtt
    18961 cctcaagggg atcgggacag ggttgagccg ttcgcccgcg gaggactacc tcggcaccga
    19021 ccacgaccgc caccccgacg gctggaccat ggtcggcgtc cccgccgacg gccagcacgc
    19081 ggcggccgtc gccgtggccg ggcccgcccc cgcgcgggtg gacgtcaggt gggtgccgga
    19141 cgcctggctg tccgtcggcc acaccgtgtg ctcgggcacc gccccgggac cgcgccccgc
    19201 cgccctcgcc ggctgaaccg aaccccgcag aaaaggacgt gaccggatga cccgcaccgc
    19261 cttcgtcttc ccgggccagg gctccgaatg cgccggcctg ggcagggagc tgctcgccct
    19321 gcgcccggac ctcgccgaca cctactaccg caccgccgac gacctcctcg gcatcccgct
    19381 ggcccggatc tgccgtgacg gttccccccg ggacttcgag gacccggcgg tggcccagcc
    19441 cgccgtgttc ctgacgagcc tggccgtcct ggaggtgctg cgcggcgagg ggctggagcc
    19501 ggacgccgtg gccgggcaca gcctgggcga gtacgcggcg ctggtggccg cgggcgtcct
    19561 ggagtggacc gaggcgctgt ggctggtccg gctgcgcgcc gagctcgtcg ccacggccgg
    19621 ggaccggatc ggcagcgcca ccgtggcggt catcggcccg ccccgctcgg acctggtgcg
    19681 gctgtgcgcc gaggcccggg cggccaccgg ccaggtcgtg gaggtggccg gggacaacga
    19741 gccccggcag accgtggtgt cgggccaggc cgcggcggtg gagcgggtcg cgcgggaggc
    19801 cggggcggcc ggggcacggg tggagcggct gcgcaccggc ggacccttcc actccagcct
    19861 gctgggcgag gccgcggcgg agttcaccga gacgctgatc gccacggagt tccgcgatcc
    19921 ggccgtcccg ctggtctccg gcgtcaccgg cgggtgggtg acgacggccg ccgaggccgc
    19981 cgtgaccctg cgcggccagc tgaccagccc ggtgcgctgg accgaggcgg tggcgacgct
    20041 cgccggctcg ggcgtcgacc ggtacgtgga ggtgggcccc ggccgggtgc tgagcggact
    20101 ggtgcgccgc atcctgccgg gcgcccgggt ccatccgacg tgcaccgcgg accggctcct
    20161 gggggccgtg gacgcgctca ccgccgccac agtctgacca tcgacccacg gaaagggtgg
    20221 gagaaccatg caaggagcgg acgacacgat ccaccaccgg atcgacgagc tcacggggat
    20281 caaggagtcc gcgcgcagcg gcgacgaggg agcgaccggc cgtcagcacg ccaagggcaa
    20341 gctgacggcc cacgaacgga tcgccctgct gctcgacaag gggtcgttca ccgaggtgga
    20401 gccgctgcgc cggcaccggg ccagcggatt cgggctggag gcgaagaagc cgtacggcga
    20461 cggcgtcgtc accggctggg gcaccgtgga cgggcgcacg gtcttcgtct acgcgcacga
    20521 cttccggatc ttcggcggcg cgctgggcga ggcccacgcc acgaagatcc acaagatcat
    20581 ggacatggcc gaggcggccg gcgccccgct ggtctccctc aacgacggcg cgggcgcccg
    20641 catccaggag ggcgtctccg cgctcgccgg gtacggcggc atcttccggc gcaacacccg
    20701 ggcctccggg gtcatcccgc agatctcggt gatgctcggc ccgtgcgcgg gcggggcggc
    20761 ctactccccg gcgctcaccg acttcgtctt catggtccgc gagacctcgc agatgttcat
    20821 caccggaccc gacgtggtca aggccgtcac cggcgaggag atcacccaga acggcctcgg
    20881 cggcgccgac gtccacgccc gcgaatccgg cgtcgcgcac ttcgcgtacg acgacgagga
    20941 gacctgcatc gccgaggtcc gctacctgct ggggctgctc ccctccaaca accgcgagct
    21001 ggcgcccgtg gaacgctccg gggatccggc cgaccggccc ggcgacgcgc tgctcgacct
    21061 ggtcccggtg cagtccggcc aggcgtacga catccgcagg gtcatcgagg aggtcgtcga
    21121 cgacggcgag cacttcgagg tgcacccggg ctgggcaccc aacctggtgt gctcgctggc
    21181 ccggctcgac gggcacgtgg tcggcatcgt cgcgaacaac ccctcggcga tggccggggt
    21241 cctggacatc gaggcctccg agaagggtgc caggttcgtc cagttctgcg atgccttcaa
    21301 catccccctg gtcaccctgg tcgacgtacc gggcttcctg ccgggcgtgg accaggagca
    21361 caacggcatc atccggcgcg gcgccaaact gctgtacgcg tactgcaacg cgaccgtgcc
    21421 ccgcatctcc ctggtgctgc gcaaggccta cggcggcgcg tacatcgtca tggactcccg
    21481 ctccatcggc gccgacctgg ccctggcctg gcccaccaac gagatcgccg tgatgggcgc
    21541 cgagggcgcc gcgaacgtgg tcttccggcg cgagatcaac gccgccgagg accccgaggc
    21601 cgtgcgcgcg cagcgcatcg ccgagtacaa gagcgagctg atgcacccct actacgccgc
    21661 cgagcgcggc ctcgtggacg acgtcatcga cccgcgcgac acccgcccgg tgctgatccg
    21721 ctccctggcg atgctgcgcg ccaagcacgc cgacctgccc agccgcaagc acggaaaccc
    21781 gccgcagtga cagccggcgg gacgtcacga gacgaggagc agcccgtgga cgcgcaagcc
    21841 cccgaccatc tcatccgcgt cgtcaaagga cggcccgacg ccgcggaact cgccgcgctg
    21901 accgccgtcg tgctggcccg ggcagcggcc cacgagggcc ggcacggagg cacggcgggc
    21961 agcggtcccg ccctggccgg ctggcagcgc cccgagcggc tgcgcggctt cctcggtccg
    22021 cgcacctggc gcgaccgccg cggcgagccg cggtccgcct gacggcgccc gccgcgcacc
    22081 ccccttcctc ccaaggagag acgacatgac acaccccgtc ctcggacgga cgcgccgcga
    22141 ggaggcgtca tgaggctgct ggtcaccggc ggggccgggt tcatcggctc gcacttcgtc
    22201 cggaccctgc tcgacggcgg gtacccgggc cacgaggagg accgggtcac ggtcctcgac
    22261 aagctcacct acgctggcaa ccgggagaac ctcccggccg cccacccccg gctggacttc
    22321 gtccgggggg acgtctgcga cgaggcgctg ctgcgctccc tgctgcccgg tcacgacgcg
    22381 gtggtgcact tcgcggccga gtcgcacgtg gaccgttccg tgcactccgc ggccgagttc
    22441 gtccgcacca acgtcggcgg cacccagacc ctgctggacg cctgcctggc caccggcgtc
    22501 ggccgcgtgg tgcacgtgtc caccgacgag gtgtacggct ccatcgacga gggcgcctgg
    22561 accgaggagc ggccgctgct gcccaactcc ccgtacgccg cctccaaggc ctcctccgac
    22621 ctcatcgccc gcgcctactg gcgcacccac ggcctcgacg tgtcgatcac ccgctgctcc
    22681 aacaactacg ggccccacca gcaccccgag aagctgatcc cgctgttcgt gacgaacctg
    22741 ctggagggcg agcgggtgcc gctgtacggg gacggccgca acgtccgcga gtggctgcac
    22801 gtggacgacc actgccgggc catcgccctg gtcctggacc ggggccggtc cggcgaggtc
    22861 tacaacgtcg gcggcggcaa cgagcagacc aacctgcaca tcaccgagcg gctgctggcc
    22921 ctgtgcgggg ccgacgcctc ggccgtgcgc cgggtggccg accgcaaggg ccacgacctg
    22981 cgctacgccc tggacgagac gaagatccgc gaggagctcg ggtacgcccc gcggatcccc
    23041 ttcgagcagg gcctcgccga caccgtcgcc tggtaccggg acaacccggg ctggtggaag
    23101 gccgtgaagc accgcaccga cgacctcggc cgcaagggcc gtgaagggac caccacgtca
    23161 tgaacgtcca caaggggctc atcctcgacg agacggccaa gttccaccag gacgcccagg
    23221 acacccggcc cttcgtgccc ggcaccaccg agatctggcc ggccggcgcc gtcctcgacg
    23281 agcgcgaccg cacggccctg gtcgaggcgg cgctggagat gcggatcgcc gccggaccca
    23341 gctcgcgccg gttcgagtcg cgcttcgccc gcaagctggg ccaccgcaag gcgcacctga
    23401 ccaactcggg ctcctccgcc aacctgctgg cgatgacggc cttcacctcc cacctgctgg
    23461 aggaccggcg gctgcggccg ggcgacgagg tcatcacggt cgccgccggc ttccccacca
    23521 ccgtcaaccc gatcatccag aacgggctcg taccggtctt cgtcgacgtc gaactcggca
    23581 cctacaacac caccgccgaa cgcgtcgccc gggccatcgg ccccaagacc cgcgccatca
    23641 tgatcgccca cgccctcggc aaccccttcg aggtcgccga gatcgcccag ctggcgcagg
    23701 agcacgacct gttcctgatc gaggacaact gcgacgccgt cggctccacc tacgacggga
    23761 agctcaccgg caccttcggc gacatcacca ccgtgagctt ctacccggcc caccacctga
    23821 ccatgggcga gggcggctgc gtcctgacct cgaacctggc gctcgcccgc atcgtggaat
    23881 cgctgcgcga ctggggccgg gactgctggt gcgagccggg cgagaccaac aagtgcctca
    23941 agcgcttcaa ctaccagatg ggcaccctcc ccgagggcta cgaccacaag tacatcttct
    24001 cccacgtggg ctacaacctg aaggccaccg acatccaggc ggcgctcggg ctcacccagc
    24061 tggacaagct cgacgggttc tgcgacgccc gccgccgcaa ctggcgccgg ctgcgcgacg
    24121 gcctcgacgg ggttccgtac ctgatcctcc ccgaggccac cccgcgcagc gacccgagct
    24181 ggttcggctt cgcgctcacc gtggaccccg aggcccccta cagccgggcc gccctcgtgg
    24241 acttcctgga ggggcgcaag atcggcacgc ggcgcctgtt cgcgggcaac ctcacccgcc
    24301 accccgccta catcgaccag ccccaccgca tcgtcgggga cctcaccaac agcgacgtca
    24361 tcaccgacca gaccttctgg atcggcgtct acccggcgct gaccgaggag atgctcgact
    24421 acgtgatctc ctccgtcaag gagttcgtcg ggggccacgc gtgagcgccc ccgcccccgc
    24481 ccgtccggtg ccgggccccc gcttcgacgc ggacgccgcc gagcgcttcg cccgctccgc
    24541 cgccgtccgg cagggggtcg tacggcacac cgacgaggtc cacggctggc tggaggaacg
    24601 ccgccgggcc caccgcttcc gggtcgagcg catccccttc gccggactcg acggctggtc
    24661 cttcgacccc ggcagcggca acctcggcca ccgcagcggg aagttcttca ccgtcgaggg
    24721 cctgcgggtg accacctcca ccgacggccg cgaccggcag tggcaccagc cgatcatccg
    24781 ccagcccgag gtcggcatcc tcgggatcct ggtcaaggag ttcgacggag tcccgcactt
    24841 cctgatgcag gccaagatgg agccgggcaa ccgcaacctg ctccagctgt ccccgacggt
    24901 gcaggccacc cgcagcaact acaccaaggc ccaccggggc gccgacgtgc gctacgtcga
    24961 gtacttcacc gacccccgcc ggggccgggt cctcgccgac gtgctccagt ccgagcacgg
    25021 ctcgtggttc ctgcgcaaga gcaaccgcaa catgctcgtc gaggccgtgg gcgaggtgcc
    25081 cgagcacgag gacttccgct ggctgaccct cggccagatc ggcgagctgc tccaccggga
    25141 caacctcgtc aacatggacg cccgcaccgt gctcgcctgc gcgccccacg cggacccgga
    25201 cggcctcgcc ctgcaccggg acaccgagct gcggtcctgg ttcaccgccg aacgctcccg
    25261 ccacgacgtg gccgccgacc gcgtgcccct ggcggacctg cccggctgga agcgcaccga
    25321 acactccatc gaccacgagg agggccgctg gttcggcgtc gtcgcggtcg ccgtccaggc
    25381 gggcagccgc gaggtctccg gctggacgca gccgctgttc gagcccgtcg gcaccggcgt
    25441 caccgccttc ctgacccgcc ggatcggcgg cgtcgcccac ctgctggtgc acgcccgggt
    25501 cgaggcaggc ttcgccgaga cggtcgagct cggccccacc gtccagtaca cccccgccaa
    25561 ctacgcccac ctgccggacg ccgaacgccc gcccttcctg gacctggtgc tcggcgccga
    25621 cccggcgcgg atccgctacg aggccctgca ctccgaggag ggcggccggt tcctcaacgc
    25681 cgagagccgc tacctcttcc tcgacgtgga cgaggaccag gccccgctcc aggctccgcc
    25741 cggatacctg tgggccaccc ccggccagct caccgcgctg ctgcggcaca accactacct
    25801 caacgtgcag gcccgcactc tgctctcctg cctgaccacg ggagcggtac ggctctgatg
    25861 gaccccctgc gcatcggcgt cctcggatgc gccgacatcg cccgccgccg gatgctgccc
    25921 gccctgcggg actgccccgc aaccgaactc gttgccgtcg ccagccggga cgccgcgaaa
    25981 gcccgctcca ccgccgccga ggccggctgc cgggccgtca ccggctaccg ggccctgctg
    26041 gagcgccccg acgtcgacgc cgtctacgtc ccgctcccgg cggccctgca cgccgagtgg
    26101 gtggaggcgg cgctgcgcgc gggcaaacac gtcctcgcgg agaagcccct gaccaccgac
    26161 ctcgccacca cccgccggct ggtggccctg gcgggggaac gcggccgggt gctccgcgag
    26221 aacgtgatgt tcgtccacca ctcccagcac gccgccgtcc gcgccctcgt ggccgacggg
    26281 gccatcggcg aactccgcgc gttccacgcc gagttcgcca taccccggct gcccgacacg
    26341 gacatccgcc acgacccggc cctcggcggc ggcgccctgt gggacaccgg cgtctacccc
    26401 gtccgggccg ccctgcactt cctcggcgac cggctggaga ccgaggccgc cgtcctggtg
    26461 cgcggcggac ccggccgggc cgtcgacacc tccggcacgg ccctgctgcg cgacccgtcc
    26521 ggggtctgcg cgcagctggc cttcggcctc gaccacggct accgctcccg ctacgagatc
    26581 accggcagca cggggcgcct caccgtcgac cgggccttca ccccgcccgc cggccacccg
    26641 ccccgggtcc tgttcgaacg ccgcaccggc accgaggaga tcgtcctcgc cgccgacgac
    26701 caggtgctgc gcacggtggc cgcgttcgcc gccgccgtgc gcaccgccgc cgcgcccgac
    26761 ggcgcggtgc tgcgccaggc ggaactgctc gacgggatcc ggcgccgcgc ccgcgtcctg
    26821 tgagcggtca ccgcgcgggg ccgtccggag ccgccacgcc gtacccgccc atgaagtccg
    26881 ccctctggag aggccatgcc ttcgccccac gacgagatcg cggatctgcg cgagcaggtc
    26941 cgggtcctgc gcgaccacgc cgagctgcgc gagctcttcg accgctacgt ctgcgccctc
    27001 gacaccggcg gcccgcccgg ccgggaccgc gagcgcttcg cctcgctgtt caccgaggac
    27061 gtcaccttcg ccttcccgat cggcgtctgc accggcatcg aggccttcac cgccttccag
    27121 cgcgaggccg gtgaacggtg ggcgcgcacc caccacctca gcgccggcca ccgcatcgac
    27181 ctcgacggcg accgggccac gctgcgcgtc cagcagatca ccacccacgt ccaccacatc
    27241 acggacgcgg cgcccgccca cttcgacgtc ggcgggtacg ccgaggcccg cgccgtgcgc
    27301 accggggccg gctggcggct gagccacgtc gccttccacg tcgtgtggga ctcgggcgtc
    27361 cgcctccccg aactgaccgg agtccagctg tgaggaccgg atgaacgccg tgcagatcgc
    27421 cgggtactgg gtcccggcgc gcgagcccgt acgcgaggcc gcacccgatc cgctgcgcga
    27481 gcccgcgccc cgcgccccgg gccaccccgt gccgcccctg accacactcc tgcggcggcg
    27541 ggcggcctgg ggcctcgccg tcgcccgggg ccggacggta cgccaccacc gctgaccccc
    27601 gttcccctcc aggaggagcc gcatggccgc cccaccgccg cccgcaaccc ccgggatccg
    27661 gcccgtcgtc ctcgacgcgg ccggcgttcc gctgtccgga ctcctcgcgc tgccggcgcg
    27721 gcccgtgccc cgggccgtcg tggtggccct gcacggcgcc gggatgagcg ccggctactt
    27781 cgacagccgg gcccgccccg ggctctcgct gctcgaactc ggcgcctccc tgggctacac
    27841 cgtcctctcc ctggaccggc ccggctacgg ggcctcggcg gcggcgctgc ccgaggggca
    27901 ggagctcgcc gggcagaccg aaaccctgct cgcggccctg gaggacttcg cccgcggcca
    27961 cgaactcggc gcgggctact tcctcgtggc ccactccaac ggcggccggc tcgccctgtc
    28021 cgccgcgggt gccggggacg gtttcgcgcc gctcggcgtg gacctgagcg gtctcggccg
    28081 gcgcttcgcc gtggagctcg ggcagctgcc cgggacgacg gcggacctgc ggagccagtg
    28141 gcgccggcac tggggggcgc tgcgcttcta cccgccggac gccttccggc aaggcgcgga
    28201 actgatccgt ccggtgccgg tcctggaggc ccgggagacc atgcggtggc cggacgcgta
    28261 ccccgcgatc gcggcccggg tgggggtccc ggtccgcttc accttcgcgg aacaggagct
    28321 gtggtggagg accgacggcg gggctctgga ggaactcctg agtccgctgt ccggggcccc
    28381 cgtggaggct gtccgccagc ccgattccgg tcataacatc agtctcggct gggccgcccg
    28441 cacctaccac ctgcgggtcc tcgccttcct ggaggagcgt ctgctcgccc gcgacgccgc
    28501 cctcaccgct cccgtggcga cgccctga
//
