BGC0000204: benastatin A biosynthetic gene cluster from Streptomyces sp. A2991200
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Location: 1 - 17,480 nt. (total: 17,480 nt).
This entry is originally from NCBI GenBank AM501485.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Polyketide
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000204
Short description benastatin A biosynthetic gene cluster from Streptomyces sp. A2991200
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide (Angucycline)
Loci NCBI GenBank: AM501485.1
Compounds
  • benastatin A
  • benastatin B
  • BE-43767
  • TAN1532B
Species Streptomyces sp. A2991200 [taxonomy]
References
Chemical products information
benastatin A
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C30H28O7
Chemical database entries
NPAtlas
PubCHEM
ChemSpider
benastatin B
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C30H30O7
Chemical database entries
NPAtlas
PubCHEM
ChemSpider
BE-43767
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C29H26O8
TAN1532B
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C29H28O8
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • CAM58794.1
  • benG
 4243 - 4698 (+) BenG protein
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  • CAM58795.1
  • benF
 4867 - 6045 (-) C-dimethyltransferse
  • Tailoring (Methylation)
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  • CAM58796.1
  • benE
 6112 - 6432 (+) BenE protein
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  • CAM58797.1
  • benD
 6432 - 6875 (+) BenD protein
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  • CAM58798.1
  • benA
 6865 - 8136 (+) BenA protein
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  • CAM58799.1
  • benB
 8133 - 9362 (+) BenB protein
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  • CAM58800.1
  • benC
 9436 - 9696 (+) BenC protein
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  • CAM58801.1
  • benH
 9698 - 10537 (+) BenH protein
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  • CAM58802.1
  • benJ
 10531 - 10878 (+) BenJ protein
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  • CAM58803.1
  • benR
 11178 - 13148 (+) BenR protein
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  • CAM58804.1
  • benL
 13292 - 14041 (-) C-19 ketoreductase
  • Tailoring (Reduction)
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  • CAM58805.1
  • benQ
 14179 - 15189 (-) BenQ protein
  • Precursor biosynthesis
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Polyketide-specific information
Subclass Angucycline
Starter unit Hexanoyl-ACP
Ketide length 14
Cyclic? yes
Polyketide-synthases
Genes Properties Modules
benH
+
benD
+
benE
+
benA 		Synthase subclass: Type II
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: F65XGYSSLMUEJC2Q4T3BLCPS, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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