BGC0000208: chelocardin biosynthetic gene cluster from Amycolatopsis sulphurea
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Location: 1 - 26,101 nt. (total: 26,101 nt).
This entry is originally from NCBI GenBank KC870000.2.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000208
Short description chelocardin biosynthetic gene cluster from Amycolatopsis sulphurea
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
KC870000.2
via
Compounds
  • chelocardin
Species Amycolatopsis sulphurea [taxonomy]
References
Chemical products information
chelocardin Evidence:
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C22H21N1O7
Chemical database entries
NPAtlas
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • QPT54834.1
  • orf1
 452 - 1399 (+) hypothetical protein
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    • QPT54835.1
    • orf2
    		 1396 - 2874 (+) hypothetical protein
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      • AHD25926.1
      • chdP
      		 3079 - 4377 (+) putative keto-acyl synthase alpha
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        • AHD25927.1
        • chdK
        		 4374 - 5630 (+) putative keto-acyl synthase beta
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          • AHD25928.1
          • chdS
          		 5655 - 5921 (+) putative acyl carrier protein
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            • AHD25929.1
            • chdQI
            		 5993 - 6901 (-) putative cyclase/aromatase
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              • AHD25930.1
              • chdMII
              		 6990 - 8021 (-) putative methyltransferase
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                • AHD25931.1
                • chdGIV
                		 8185 - 9384 (+) putative glycosyltransferase
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                  • AHD25932.2
                  • chdTn
                  		 9589 - 11124 (+) putative transposase
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                    • AHD25933.1
                    • chdR
                    		 11263 - 12708 (-) putative exporter
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                      • AHD25934.1
                      • chdA
                      		 12859 - 13431 (+) putative transcriptional regulator
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                        • AHD25935.1
                        • chdN
                        		 13445 - 14791 (-) putative aminotransferase
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                          • AHD25936.1
                          • chdOI
                          		 14924 - 16138 (+) putative oxygenase
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                            • AHD25937.1
                            • chdMI
                            		 16146 - 17171 (-) putative methyltransferase
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                              • AHD25943.1
                              • chdL-chdOIII
                              		 17249 - 19180 (-) putative acyl-CoA ligase/oxygenase fusion protein
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                                • AHD25939.1
                                • chdX
                                		 19206 - 19658 (-) putative cyclase
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                                  • AHD25940.1
                                  • chdT
                                  		 19823 - 20611 (+) putative ketoreductase
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                                    • AHD25941.1
                                    • chdQII
                                    		 20640 - 21587 (+) putative cyclase/aromatase
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                                      • AHD25942.2
                                      • chdOII-chdY
                                      		 21580 - 24000 (+) putative oxygenase/cyclase fusion protein
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                                        • QPT54836.1
                                        • chdB
                                        		 24167 - 24943 (+) SARP family transcriptional regulator
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                                          • QPT54837.1
                                          • chdC
                                          		 24987 - 25625 (-) LuxR family transcriptional regulator
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                                            Biosynthesis information
                                            Annotation changelog

                                            Entry version: 4

                                            Date
                                            Changes
                                            Submitters
                                            Reviewers
                                            2022-10-07
                                            Update chemical activity to schema version 2.11
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                            Entry version: 3

                                            Date
                                            Changes
                                            Submitters
                                            Reviewers
                                            2022-09-15
                                            Updated to a complete accession
                                            • (ID: SJG3CBEHSM6A3I74YXLH6GLA)
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                            2022-09-15
                                            Updated bioactivity data
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                            Entry version: 2

                                            Date
                                            Changes
                                            Submitters
                                            Reviewers
                                            2019-10-16
                                            Migrated from v1.4
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                            2019-10-16
                                            Updated compound(s) information (NPAtlas curation)
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                            Entry version: 1

                                            Date
                                            Changes
                                            Submitters
                                            Reviewers
                                            2015-06-12
                                            Submitted
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                            Detailed domain annotation
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