LOCUS       BGC0000209             41528 bp    DNA     linear   BCT 22-JAN-2015
DEFINITION  Streptomyces aureofaciens strain F3 chlortetracycline biosynthesis
            gene cluster, partial sequence.
ACCESSION   BGC0000209
VERSION     BGC0000209
KEYWORDS    .
SOURCE      Kitasatospora aureofaciens
  ORGANISM  Kitasatospora aureofaciens
            Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
            Kitasatospora.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.2.0-924c3663(changed)
            Run date     :: 2022-11-07 17:43:59
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 41528
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     gene            complement(<1..284)
                     /gene="ctc9"
     CDS             complement(<1..284)
                     /codon_start=1
                     /gene="ctc9"
                     /product="Ctc9"
                     /protein_id="AEI98637.1"
                     /transl_table=11
                     /translation="MEEQRAGSRVSRPEIRLVRRGFTDPAKAVRLLDGPGLEGLADDPV
                     LLDALGATADPDLALLGLARLLEAADESERHTLRDTLTTSKPLRDRLLGV"
     source          1..41528
                     /db_xref="taxon:1894"
                     /mol_type="genomic DNA"
                     /organism="Kitasatospora aureofaciens"
                     /strain="F3"
     misc_feature    <1..>41528
                     /note="chlortetracycline biosynthesis gene cluster"
     protocluster    1..41528
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[32655:35141]"
                     /cutoff="20000"
                     /detection_rule="(t2ks and t2clf)"
                     /neighbourhood="35000"
                     /product="T2PKS"
                     /protocluster_number="1"
                     /t2pks_malonyl_elongations="8|9 (Score: 672.5; E-value:
                     4e-205)"
                     /t2pks_molecular_weights="malonamyl-CoA_8 (Da): 473.898"
                     /t2pks_molecular_weights="malonamyl-CoA_9 (Da): 515.935"
                     /t2pks_product_classes="anthracycline"
                     /t2pks_product_classes="aureolic acid"
                     /t2pks_product_classes="tetracycline"
                     /t2pks_starter_units="malonamyl-CoA (Score: 2237.0;
                     E-value: 0)"
                     /tool="antismash"
     proto_core      32656..35141
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(t2ks and t2clf)"
                     /neighbourhood="35000"
                     /product="T2PKS"
                     /protocluster_number="1"
                     /t2pks_malonyl_elongations="8|9 (Score: 672.5; E-value:
                     4e-205)"
                     /t2pks_molecular_weights="malonamyl-CoA_8 (Da): 473.898"
                     /t2pks_molecular_weights="malonamyl-CoA_9 (Da): 515.935"
                     /t2pks_product_classes="anthracycline"
                     /t2pks_product_classes="aureolic acid"
                     /t2pks_product_classes="tetracycline"
                     /t2pks_starter_units="malonamyl-CoA (Score: 2237.0;
                     E-value: 0)"
     cand_cluster    1..41528
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(t2ks and t2clf)"
                     /kind="single"
                     /product="T2PKS"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..41528
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0000209"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..41528
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T2PKS"
                     /region_number="1"
                     /rules="(t2ks and t2clf)"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(403..1644)
                     /gene="ctc8"
     CDS             complement(403..1644)
                     /codon_start=1
                     /gene="ctc8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /product="Ctc8"
                     /protein_id="AEI98638.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.6e-21,
                     bitscore: 68.1, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MARPAVTESLTVLIPAHNEADFIADAVKSAFGQTVRPRTVLVLAD
                     SCTDGTAAIARRCGAEVLEVDCRSKPESLNLALAEVTTEFVALLDADGYFASDRALEMC
                     LERMRAKGYGGVCMSVTPHSVKGVFQRSRVIEWAAAHRMSRTVESWHGWVAVLSGCAGV
                     YRTESVRAVGGWSADSLCEDVELALKMNRAGHKAGFVPGAYVCVRDPGSWSVYWAQTHR
                     WAAGWAQALYKHRSLFLHSWGFTRVFGAMLVDSVLMASGYLSLLYQLATRFTHFDAFRW
                     MGLWFLMMVALTFGTAALQIGIRRTLTCYPAYLVVGTMGTVVSLWVMFREWVLGRHLIS
                     WTGRQGRRREITRMSERRRFVLALTGAGAGLVGALSGRVLAREYLFLTGAAATGSVLLS
                     ALLWHLVNRMPERA"
     gene            1986..2753
                     /gene="ctc7"
     CDS             1986..2753
                     /codon_start=1
                     /gene="ctc7"
                     /product="Ctc7"
                     /protein_id="AEI98639.1"
                     /transl_table=11
                     /translation="MAATTAATSAAVPAPAPAAAAAPRTQRTTVLLDRFDTLDLGPGRR
                     WGWQTAAYADCTYNPNSWKLDRLTTDALSTADGHLTVTAQHRADGNWNTGLLTTGDSCD
                     SGGSGFQLRTGDLVVVHVRLPAAGTAAWPCLWTWRDGGNELDLFEWYADHPDRIEFVNH
                     VRENGTVYYGPDIGPERWVYVAVRLGTDNDTWYVGSSRDQLNPVWSDGTGVGPDFSAYL
                     ILSLSIGDGTFHAPPTRTDPVTMEVDLLSVERP"
     gene            complement(2787..3569)
                     /gene="ctc6"
     CDS             complement(2787..3569)
                     /codon_start=1
                     /gene="ctc6"
                     /product="Ctc6"
                     /protein_id="AEI98640.1"
                     /transl_table=11
                     /translation="MCPLAVGWGGALKWRPVRWRRREPGMARQRGVVVRAVARWTGDGL
                     LTFGLLVLLFAVYVLWWSNVVSDRAADRAAGRLRDSWSAAAPPAADADSPVAGLGRGDL
                     GFLHVPAMGRDYEVLIRSGTDEATLADGVAGAYTVPYRSVPPWEGEGNFALAAHRDGHG
                     AKFHDLDQVGPGAPVVVETRDRWYVYRVDGVLPETSPDDVGVIAPVPTGSPYRSPGRYI
                     TLTTCTPEYTSLYRLVVWGSLVREEAMTPGRVPPAELR"
     gene            complement(3691..5052)
                     /gene="ctc5"
     CDS             complement(3691..5052)
                     /codon_start=1
                     /gene="ctc5"
                     /product="Ctc5"
                     /protein_id="AEI98641.1"
                     /transl_table=11
                     /translation="MGKQQQFVLRTLEERDIRFVRLWFTDVLGFLKSVAVAPAELEQAF
                     EEGIGFDGSAIEGFARVYESDMIAKPDPTTFQILPWRSETPGTARMFCDILMPDGSPSY
                     ADPRFVLKRTLEKASDLGFTFYTHPEIEFFLLKNLPGDGTAPIPADQSGYFDHTPRGVG
                     HDFRRQAITMLESMGISVEFSHHEGAPGQQEIDLRYADALSTADNIMTFRLVMKEVALE
                     QGVHASFMPKPFSEHPGSGMHTHVSLFEGDRNAFHESGAEYQLSKVGRSFIAGLLRHAA
                     ETAAVTNQWVNSYKRIWGGSQRTAGAGGEAPSYICWGHNNRSALIRVPMYKPGKQGSTR
                     IEVRSLDTGCNPYLAYAVTLAAGLKGIEEGYELPPGADDDVWALTDSERRALGIQPMPQ
                     NLGEAIDLMQRSELVAETLGEHVFDFFLRNKRQEWEEYRSEVTPFELRKNLQVL"
     gene            5228..6982
                     /gene="ctc4"
     CDS             5228..6982
                     /codon_start=1
                     /gene="ctc4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1294:Nitrilase/cyanide hydratase and apolipoprotein
                     (Score: 166.3; E-value: 1.4e-50)"
                     /gene_kind="biosynthetic-additional"
                     /product="Ctc4"
                     /protein_id="AEI98642.1"
                     /transl_table=11
                     /translation="MPNLRVALCQIDPWVGDLTRNGDEVVRWTKQAVEAGAQLVAFPEM
                     VLTGYPVEDLALRRSFVEASRGALVELAGRLADDGLGGVPVVVGYLGRSEHASPRFGRP
                     AGSPQNCAAVLYRGEVVTRFAKHHLPNYGVFDEFRWFVPGDQLPVLRLHGVDVALAICE
                     DIWQDGGRVTAAREAGAGLLLVVNGSPYERNKDDLRLELVRRRAVEAGCALAYVNMVGG
                     QDELVFDGDSIVVDADGRVLARSPQFEEHLLVLDLDLPAASSDHTDGLLLSDGLHLVRT
                     ELGDEPSPAPADRLTAGIAPRLSDEAEIWAALVSGTRAYVVKNGFESVLIGLSGGIDSA
                     LVAAIAVDAIGAGNVHCVSMPSRYSSQHSRDDAAELARRTGLHFRTVSIAPMFDAYLGA
                     TELTGLAEENLQSRLRGTLLMAISNQEGHIVLAPGNKSELAVGYSTLYGDSVGAFGPIK
                     DVYKSLVFRLARWRNEEAERRGEVPPIPENTITKPPSAELRPDQVDTDSLPDYDLLDSV
                     LDRYIEGDEGRDAIVAAGFDPAVVDRVVRLVDTAEYKRRQYPPGPKISVKNFGRDRRLP
                     ITNRWRRG"
     gene            7048..8547
                     /gene="ctc3"
     CDS             7048..8547
                     /codon_start=1
                     /gene="ctc3"
                     /product="Ctc3"
                     /protein_id="AEI98643.1"
                     /transl_table=11
                     /translation="MRGEDGLFEIEPVEVKRTPGRPAAVDKTFRTFDPHQVLLLPPSLD
                     DWLPEGHLARFVADLVDEVLDLSPILADYTEKRGYPPYDPRLMVRLLIYGYTTGVRSSR
                     AIERKCSDDVAFRFLAADQTPDFRSIARFRRRHLDALADLFTQSLHLATKLGMVKMGRV
                     ALDGTKLEANASKHKAMSYGRLIDKEEQVEAEIAALEAKAAALLADAEATDEAEDATFG
                     VDGKDMDLPAELDRREKRLARLQAARAQIEAEAADKARRHAEDKERRRRQRTGTNDQQA
                     VIDAGEAAAAKARPKPKAQANFTDPDSRIMKNSDGAYIQAYNAQAVVDEALQVITAADV
                     MTNASDALNYTTMLDQSAQNTGRHPKQALVDAGYCSETNLEAARERQLACGTDTFMATG
                     RLGHDEQVQPAPRGRIPKDATLKERMARKLRTKPGRKAYSRRKAIVEPVFGQITTCQNG
                     RQLLLRGEDGARGEWRLLAACHNLRKIFRHAGTAGIAALAG"
     gene            9658..10305
                     /gene="ctcA"
     CDS             9658..10305
                     /codon_start=1
                     /gene="ctcA"
                     /gene_functions="regulatory (smcogs) SMCOG1016:LuxR family
                     DNA-binding response regulator (Score: 90; E-value: 2e-27)"
                     /gene_kind="regulatory"
                     /product="CtcA"
                     /protein_id="AEI98644.1"
                     /transl_table=11
                     /translation="MSVGNNHPSVLVVEDNVLLRTGLQALLSAEPDLVLRAAVGGVDEA
                     LAVMAGHPVDVVVYGAGESVADTERGLERLLDRGTRVVVLSRRDHPGEMETYLSSGVHA
                     YLAEDAAGECLGLVIRGLTSDRERVYIMASRSGLDWMAGQRGNRLSGREREVMGLVANG
                     LSNSAIAGRLCISPGTVKRHLRNVFVKLNAVSRIDAVNKARAASMLVPAGRA"
     gene            complement(10418..11227)
                     /gene="ctcB"
     CDS             complement(10418..11227)
                     /codon_start=1
                     /gene="ctcB"
                     /gene_functions="regulatory (smcogs)
                     SMCOG1041:transcriptional regulator, SARP family (Score:
                     293.7; E-value: 5.7e-89)"
                     /gene_kind="regulatory"
                     /product="CtcB"
                     /protein_id="AEI98645.1"
                     /transl_table=11
                     /translation="MKFNILGPLEVLDKGIPCTPSALKVRWTLAVLLMNANRIVDLGLI
                     IEEIWGSSPPRTVVTTAQTYIYQLRKLCRPLGREVILTKAPGYVLLLGEEELDAQEFER
                     LHHEGDRLLVAGHPEAAAQRLRQALDLWRGTALADIPVGAPLAGHVAVLEEMRLRALEH
                     RILADRQLGRHRELIPELRLLTLHQPMNEWYHEQLMLALDAAGRRSEALHVYRVLYRRL
                     DEDLGIAPSRPLQELHNDLLSGTSPTRQEFQALAARAMEQGLRARSA"
     gene            11579..13561
                     /gene="ctcC"
     CDS             11579..13561
                     /codon_start=1
                     /gene="ctcC"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1190:GTP-binding protein LepA (Score: 146.8; E-value:
                     1.6e-44)"
                     /gene_kind="biosynthetic-additional"
                     /product="CtcC"
                     /protein_id="AEI98646.1"
                     /transl_table=11
                     /translation="MTTVNIGILAHVDAGKTSLTERLLHTAGVIDRVGSVDRGDTQTDS
                     HELERQRGITIRSAVVSFTVGDVKVNLIDTPGHPDFISEVERALGVLDGVVLVISAVEG
                     VQAQTRLLMRTLVKLRMPVILFVNKIDRMGARYHELLDEIRSELTPAVVALTRVEGPGT
                     PGARAFARTVGTDDPDFAAELADILAEHGDDFLARYLEDETSLTAQDYSAELARQAARG
                     QLYPVLFGSAVAGVGIDALVDGITRLFPVNHGGSGGTLRGTVFKIERGWAGEKVAYVRL
                     HGGELGSREKVSVFRRDQHGAVTEIPGRTTVVEVFDRGSAVVESRARAGDIAKVWGLKG
                     IRIGDRLGSAEGLDGEHLFAPPSLETVIRPSRPSAMPELYDALLQLADQDPFINVRKDD
                     EEQEIAVSLYGEVQKEVIAATLADEFKLDVAFEGTRIICVERPIGVGESVEEIDYRSKT
                     FFWATIGLRVEPGEPGSGVVFRRSVELGSLPHAFHKAVEEAVRATLQQGLNGWEVLDIL
                     VTLTRSGFASPVSAAGDFRKLTPLVLMNALKQAGTQVYEPVNRFELEVPGENASAALLS
                     LVECGATPESTRGLGSSCLVEGTIPARTVQEFEQRLPGLSQGQGVLVTRFHSFQPVVGA
                     APRRRRTDLNPVDRSEYMLRAFGRI"
     gene            complement(13635..14405)
                     /gene="ctcD"
     CDS             complement(13635..14405)
                     /codon_start=1
                     /gene="ctcD"
                     /gene_functions="biosynthetic-additional (t2pks) CYC
                     C5-C14/C3-C16 (Score: 435.9; E-value: 1.1e-133)"
                     /gene_kind="biosynthetic-additional"
                     /product="CtcD"
                     /protein_id="AEI98647.1"
                     /transl_table=11
                     /translation="MRLIDLSSTIDANAWEVDGIRHEVLTPADGARHMAEGMLRDHGLE
                     FDVADLPDGELLSLDTLTLTTHTGTHVDAPSHYGSRAAYGVPRHIDELPLEWFIGPGVR
                     LDLTDCGVGTVGVDRLRRAFDEIDHRPSAGEIVLLHTGAERLAGTPEYFTRFAGLDGAA
                     TNLLLDLGVRLIGTDAFGLDAPFTHMLAEFQRTRDRSVLWPAHFAGRQREYCQIERLSN
                     LGALPAPTGFTVQAFPVKIAGAGAGWTRAVALLD"
     gene            complement(14392..16017)
                     /gene="ctcE"
     CDS             complement(14392..16017)
                     /codon_start=1
                     /gene="ctcE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050:monooxygenase FAD-binding (Score: 408.2; E-value:
                     9.4e-124)"
                     /gene_functions="biosynthetic-additional (t2pks) OXY
                     (Score: 433.8; E-value: 2e-132)"
                     /gene_kind="biosynthetic-additional"
                     /product="CtcE"
                     /protein_id="AEI98648.1"
                     /transl_table=11
                     /translation="MADPAPAVLIAGAGPVGLTTAHELARRGVPVRLVDAAPGPATSSR
                     ALAVHARTMEVLEQMGALDRLLPLGRRVTHFTMHRRGRTLIRFDTNYRSLPTRYPFSLM
                     VDQVVTEQVLRERTAELGVPVEWGVELTALQTGPDSVLVTLRHADGRTEETRVPWLVGA
                     DGGRSTVRKQLGMRLIGDSTEVWLNADVTLDADLPPDSNHLLHTEPGTLLLVPFPEPGK
                     WRVVDTVDTDGAEDRELVRRRLADKIGRALGRPVQVGTPTWLSVFTVQQRQITRMREGR
                     CFLAGDAAHVHSPASGQGMNSGIQDAYNLAWKLADVIRGHAGPALLDSYDAERVPTGAV
                     LLRSTRTATALVSLRTALAPALLTVGTAALRRITPLRRKVEGRMIRGFCGLALAYPDSP
                     LTRPAGSRAGRPSPGDRVGCDARTAAGHPGWSALCAELADPRWTLLATPAEGGSTGYRE
                     ALARVERLFGSAVSVRTVADPGAPGELPDPGGVLRRELGLAPGEFLLIRPDGHLAARDR
                     GPERCLDVLRDCALLPEGAAHAPH"
     gene            complement(16010..16948)
                     /gene="ctcF"
     CDS             complement(16010..16948)
                     /NRPS_PKS="Domain: Polyketide_cyc2 (5-146). E-value:
                     1.4e-16. Score: 53.0. Matches aSDomain:
                     nrpspksdomains_ctcF_Polyketide_cyc2.1"
                     /NRPS_PKS="Domain: Polyketide_cyc2 (155-307). E-value:
                     1.1e-16. Score: 53.3. Matches aSDomain:
                     nrpspksdomains_ctcF_Polyketide_cyc2.2"
                     /codon_start=1
                     /gene="ctcF"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1128:cyclase/dehydrase (Score: 417.8; E-value:
                     4.7e-127)"
                     /gene_functions="biosynthetic-additional (t2pks) CYC C7-C12
                     (Score: 439.0; E-value: 1.8e-134)"
                     /gene_kind="biosynthetic-additional"
                     /product="CtcF"
                     /protein_id="AEI98649.1"
                     /transl_table=11
                     /translation="MSTIQHTTHSIDVDAPAEVVYTVIADALAWPRRFAPTLHVEREEL
                     GPGAERLKIWARANGEVKHWTSRRDLDADLRRIRFRQEASSAPVSSMAGEWQVAERPGG
                     TTLTLTHEFSALDDDPQGLRWISEATDRNSRSELAGIKDLAERWNRLAEFEFEFEDSVL
                     VDAAPEAVYDFLRDAAAWPARLPHVARLDLREEAGGIQHMSMDTRTADGSEHTTESIRI
                     CFPESGIAYKQLRTPSMMAAHTGRWTVEPTDRGVRVTSWHAVVLNPEAVPTVLGPDATA
                     ATARRFIREAAGGNSRATLGLAKRFAEERRG"
     aSDomain        complement(16028..16483)
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctcF_Polyketide_cyc2.2"
                     /domain_subtype="Polyketide_cyc2"
                     /evalue="1.10E-16"
                     /label="ctcF_Polyketide_cyc2.2"
                     /locus_tag="ctcF"
                     /protein_end="307"
                     /protein_start="155"
                     /score="53.3"
                     /tool="antismash"
                     /translation="FEFEDSVLVDAAPEAVYDFLRDAAAWPARLPHVARLDLREEAGGI
                     QHMSMDTRTADGSEHTTESIRICFPESGIAYKQLRTPSMMAAHTGRWTVEPTDRGVRVT
                     SWHAVVLNPEAVPTVLGPDATAATARRFIREAAGGNSRATLGLAKRFA"
     aSModule        16028..16933
                     /domains="nrpspksdomains_ctcF_Polyketide_cyc2.1"
                     /domains="nrpspksdomains_ctcF_Polyketide_cyc2.2"
                     /incomplete
                     /locus_tags="ctcF"
                     /tool="antismash"
                     /type="unknown"
     aSDomain        complement(16511..16933)
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctcF_Polyketide_cyc2.1"
                     /domain_subtype="Polyketide_cyc2"
                     /evalue="1.40E-16"
                     /label="ctcF_Polyketide_cyc2.1"
                     /locus_tag="ctcF"
                     /protein_end="146"
                     /protein_start="5"
                     /score="53.0"
                     /tool="antismash"
                     /translation="HTTHSIDVDAPAEVVYTVIADALAWPRRFAPTLHVEREELGPGAE
                     RLKIWARANGEVKHWTSRRDLDADLRRIRFRQEASSAPVSSMAGEWQVAERPGGTTLTL
                     THEFSALDDDPQGLRWISEATDRNSRSELAGIKDLAE"
     gene            complement(17039..17827)
                     /gene="ctcG"
     CDS             complement(17039..17827)
                     /NRPS_PKS="Domain: PKS_KR (8-119). E-value: 3.6e-12. Score:
                     38.4. Matches aSDomain: nrpspksdomains_ctcG_PKS_KR.1"
                     /codon_start=1
                     /gene="ctcG"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     246.6; E-value: 4.4e-75)"
                     /gene_functions="biosynthetic-additional (t2pks) KR C9
                     (Score: 445.3; E-value: 1.5e-136)"
                     /gene_kind="biosynthetic-additional"
                     /product="CtcG"
                     /protein_id="AEI98650.1"
                     /sec_met_domain="adh_short (E-value: 9.7e-39, bitscore:
                     124.4, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTVTTGDVALVTGATSGIGLASAERLARRGLSVFICARTAQGVA
                     ETVARLRGEGLEVDGLAADVRSAQDVSTVVRAAVDRFGPIGVLVNNAGRNGGGVTSTLT
                     DELWQDVIDTNLTSVFRVTREVLTTGGMEAAGHGRIISVASTGGKQGVPLGAPYSASKA
                     GVIGFTKALAKELAHTGTTVNAVCPGYVETPMAVRVRQAYAATWATTEEDVLSRFEQKI
                     PLGRYSTAEEVAGMVDYLTTPDAASVTAQAINVCGGLGIY"
     aSDomain        complement(17471..17803)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctcG_PKS_KR.1"
                     /evalue="3.60E-12"
                     /label="ctcG_PKS_KR.1"
                     /locus_tag="ctcG"
                     /protein_end="119"
                     /protein_start="8"
                     /score="38.4"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VALVTGATSGIGLASAERLARRGLSVFICARTAQGVAETVARLRG
                     EGLEVDGLAADVRSAQDVSTVVRAAVDRFGPIGVLVNNAGRNGGGVTSTLTDELWQDVI
                     DTNLTSV"
     CDS_motif       complement(17735..17797)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctcG_0001"
                     /evalue="3.40E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctcG"
                     /protein_end="31"
                     /protein_start="10"
                     /score="19.7"
                     /tool="antismash"
                     /translation="LVTGATSGIGLASAERLARRG"
     gene            18011..18478
                     /gene="ctcH"
     CDS             18011..18478
                     /codon_start=1
                     /gene="ctcH"
                     /gene_functions="biosynthetic-additional (t2pks) CYC
                     C1-C18|C2-C19 (Score: 230.8; E-value: 1.1e-71)"
                     /gene_kind="biosynthetic-additional"
                     /product="CtcH"
                     /protein_id="AEI98651.1"
                     /transl_table=11
                     /translation="MGASALPNHRRNEEARSMTGSLYEEVQHFYGRQMRHLDEGEVTEW
                     AATFTEDGVFAANARPHPQEGRAAIEQGAREAAQRLADAGIRHRHWLGMLEVAAQPDGL
                     VLAKTYALIVATPKGGPAAVHLSCSCEDQLVRVDGELKVRHRQVHRDDLPA"
     gene            18491..20044
                     /gene="ctcI"
     CDS             18491..20044
                     /NRPS_PKS="Domain: AMP-binding (30-420). E-value: 9.1e-83.
                     Score: 269.9. Matches aSDomain:
                     nrpspksdomains_ctcI_AMP-binding.1"
                     /codon_start=1
                     /gene="ctcI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score: 339;
                     E-value: 6.3e-103)"
                     /gene_functions="biosynthetic-additional (t2pks) LIG
                     (Score: 764.1; E-value: 1.3e-232)"
                     /gene_functions="biosynthetic-additional (t2pks) LIG
                     AEI98652.1_Chlortetracycline_malonamyl-CoA (Score: 1024.0;
                     E-value: 0)"
                     /gene_kind="biosynthetic-additional"
                     /product="CtcI"
                     /protein_id="AEI98652.1"
                     /sec_met_domain="AMP-binding (E-value: 6.4e-91, bitscore:
                     296.1, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLPRDSTTFGPPLDVVAELIGGPRIDDLVRRAAELTPRHIALVH
                     GDLVLDHAALEARVSDCAEALRAAFGGPGTVIAIAAELTVDFAVTFLGISRSGNTSAMF
                     NPLVPDDTLVHVLNSCGARAAVLSPRMHRRVQALRDRLPLLRQLVVTADALDGTPVLDA
                     LERTAVPAGEVVETACLQFTSGTTGVPKTVRLSHRNLLVNAAQSAHAHRLTADAVSLNN
                     LPSFHLMHLNAALAVGATHVLCPEEDRAALVGLARTWRASHLYSLPVRLSRLAGDERLP
                     DFRIPSLRAVLSGGSALPPRTTTVLQEHFGVPVVQGYGLAETSPSTHFDLPEGPTLGSS
                     GPPVAGTACRIVDVRTGAVLPVGERGEIQVRGPQLMLGYLGDGPTDAVDADGWFRTGDV
                     GRIDEAGRLFVVDRIKDVFKCDNWLVSPTEIERVLMRHPAVADCVVFDQPDELSGAVAV
                     GLVVPRGEGVDPAALAAFANARLPYYEHLRQLRLVEGIPRSATGKVQRRELRDRLFGSL
                     "
     aSDomain        18581..19750
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctcI_AMP-binding.1"
                     /evalue="9.10E-83"
                     /label="ctcI_AMP-binding.1"
                     /locus_tag="ctcI"
                     /protein_end="420"
                     /protein_start="30"
                     /score="269.9"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="RRAAELTPRHIALVHGDLVLDHAALEARVSDCAEALRAAFGGPGT
                     VIAIAAELTVDFAVTFLGISRSGNTSAMFNPLVPDDTLVHVLNSCGARAAVLSPRMHRR
                     VQALRDRLPLLRQLVVTADALDGTPVLDALERTAVPAGEVVETACLQFTSGTTGVPKTV
                     RLSHRNLLVNAAQSAHAHRLTADAVSLNNLPSFHLMHLNAALAVGATHVLCPEEDRAAL
                     VGLARTWRASHLYSLPVRLSRLAGDERLPDFRIPSLRAVLSGGSALPPRTTTVLQEHFG
                     VPVVQGYGLAETSPSTHFDLPEGPTLGSSGPPVAGTACRIVDVRTGAVLPVGERGEIQV
                     RGPQLMLGYLGDGPTDAVDADGWFRTGDVGRIDEAGRLFVVDRIKDVFKC"
     CDS_motif       19022..19081
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctcI_0001"
                     /evalue="6.00E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="ctcI"
                     /protein_end="197"
                     /protein_start="177"
                     /score="22.0"
                     /tool="antismash"
                     /translation="ACLQFTSGTTGVPKTVRLSH"
     CDS_motif       19571..19636
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctcI_0002"
                     /evalue="1.60E-06"
                     /label="NRPS-A_a6"
                     /locus_tag="ctcI"
                     /protein_end="382"
                     /protein_start="360"
                     /score="20.5"
                     /tool="antismash"
                     /translation="PVGERGEIQVRGPQLMLGYLGD"
     gene            20088..20378
                     /gene="ctcJ"
     CDS             20088..20378
                     /codon_start=1
                     /gene="ctcJ"
                     /product="CtcJ"
                     /protein_id="AEI98653.1"
                     /transl_table=11
                     /translation="MYTFINRFTVTGDVAEFETLVGEISEFMSGRPGFRSHRLYRCATD
                     ASVYVETAEWDDAASHRAATGSPEFRARVGKVMSLAKAEPAPFDLLAQHGA"
     gene            20392..21429
                     /gene="ctcK"
     CDS             20392..21429
                     /codon_start=1
                     /gene="ctcK"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:O-methyltransferase (Score: 304.8; E-value:
                     1.3e-92)"
                     /gene_functions="biosynthetic-additional (t2pks) MET C6|C8
                     (Score: 584.7; E-value: 1e-178)"
                     /gene_kind="biosynthetic-additional"
                     /product="CtcK"
                     /protein_id="AEI98654.1"
                     /transl_table=11
                     /translation="MTDNGEIIAQPVIQLRELGLAAAGAAAVRAAARLGLADALGEEPA
                     GAAELARAVNADPDTLQRLLRALACYGVFAEQPDGRYVHTGASRLLREDTPRSLKDMVL
                     WGTEPWTWELWGHLDEAVRTGKAVFPELHGMDFFDHLHAHSPESAAVFDRAMTQSSRLS
                     ALALADRLDLGGVGTVVDIAGGQGHVLATLLERNPGLRGTLLDLPEVVSGADARLQPGG
                     ALAGRATLLGGDCRREIPVQADVYLLKNILEWDDESTVLTLRNVVRAAAPGSRVIVVEN
                     LVDGSPELRFTTAMDLLLLLNVGGRKHTRAGLVSLIEEAGLTRAEVRPVNSYLHLVESV
                     VPERG"
     gene            complement(21580..22671)
                     /gene="ctcL"
     CDS             complement(21580..22671)
                     /NRPS_PKS="Domain: Aminotran_1_2 (26-359). E-value:
                     9.4e-52. Score: 168.1. Matches aSDomain:
                     nrpspksdomains_ctcL_Aminotran_1_2.1"
                     /codon_start=1
                     /gene="ctcL"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019:aminotransferase (Score: 237.9; E-value:
                     3.1e-72)"
                     /gene_functions="biosynthetic-additional (t2pks) AMIN
                     (Score: 618.7; E-value: 7e-189)"
                     /gene_kind="biosynthetic-additional"
                     /product="CtcL"
                     /protein_id="AEI98655.1"
                     /transl_table=11
                     /translation="MIERLPKFPWDVLFPYRRRAAAHPDGLVNLALGDPVDPTPEAVRA
                     ALAAAADAPGYPSTEGTPALRAAAAAWLLRREGVSVEPEAVIPAVGTKELIAWLPTMLG
                     LGPGDVVLAPQLSFPTYEVSARLAGATFVRTDDPLSYDGPAPRLLWLNSPSNPEGRVLD
                     AAELRGVVEWARERGTLVVNDECYLDHVWERSTRSVLHAEVTGGDHHGVLAVHSLSKRF
                     NLAGYRAGFAAGDPAVIATLLEVRKHAGHMVPAPVQAAMVAALGDDAHLAGQRRRYARR
                     RELLRGALVDAGFRIEHSAGALFLWATRDEPCWTTVGALADRGILVAPGEFYGAAAARH
                     VRVAVTETDERVEQAVKRLAEGI"
     aSDomain        complement(21595..22593)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctcL_Aminotran_1_2.1"
                     /evalue="9.40E-52"
                     /label="ctcL_Aminotran_1_2.1"
                     /locus_tag="ctcL"
                     /protein_end="359"
                     /protein_start="26"
                     /score="168.1"
                     /tool="antismash"
                     /translation="LVNLALGDPVDPTPEAVRAALAAAADAPGYPSTEGTPALRAAAAA
                     WLLRREGVSVEPEAVIPAVGTKELIAWLPTMLGLGPGDVVLAPQLSFPTYEVSARLAGA
                     TFVRTDDPLSYDGPAPRLLWLNSPSNPEGRVLDAAELRGVVEWARERGTLVVNDECYLD
                     HVWERSTRSVLHAEVTGGDHHGVLAVHSLSKRFNLAGYRAGFAAGDPAVIATLLEVRKH
                     AGHMVPAPVQAAMVAALGDDAHLAGQRRRYARRRELLRGALVDAGFRIEHSAGALFLWA
                     TRDEPCWTTVGALADRGILVAPGEFYGAAAARHVRVAVTETDERVEQAVKRL"
     gene            complement(22668..23090)
                     /gene="ctcM"
     CDS             complement(22668..23090)
                     /codon_start=1
                     /gene="ctcM"
                     /product="CtcM"
                     /protein_id="AEI98656.1"
                     /transl_table=11
                     /translation="MPFTAKEAAYLASQPLARLATVDGRGQPHVVPLGFHYNAELGTVD
                     VTGRGMARSLKYRHVQGHPRVSLVVDDIVDAQRWVVRGIEIRGTAVALATGGKEILPHV
                     DDELIRITPERIVSWGIDSDCQAPPLARNVGAGAQA"
     gene            23255..24727
                     /gene="ctcN"
     CDS             23255..24727
                     /codon_start=1
                     /gene="ctcN"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050:monooxygenase FAD-binding (Score: 467.7; E-value:
                     8.4e-142)"
                     /gene_functions="biosynthetic-additional (t2pks) OXY
                     (Score: 475.7; E-value: 4.1e-145)"
                     /gene_kind="biosynthetic-additional"
                     /product="CtcN"
                     /protein_id="AEI98657.1"
                     /transl_table=11
                     /translation="MDCDVVVAGAGPTGLMLACELALGGARAVVVERRREPEKHSKAMG
                     MQGRTVELLELRGLLDRFKEGAGVLQGGNFASLGVPMRFEEFDTRHPYVLLVPQLRTEE
                     LLAERARELGVRIVRGSGVTGFAQDADGVTVETDTGPLRARYLVGCDGGGSTVRKAAGI
                     SFTGQDPHMYALIGDMRFSGDLPRGEGLGPMRPVGLVNPAKRSWFGAFQHQPGVYRATV
                     AWFDRPFADRRAPVTEEEMRAALVEHTGSDHGMHDVTWLSRLTDVSRLADCYRQGRVLL
                     AGDAAHIHLPAGGQGLNLGFQDAVNLGWKLAAVVRGHGTEELLDSYGRERRPIADGVVR
                     NTRTQAVLIDPDPRYEALRQTFRDLMALPDTNRHIAGMLSGFDVAYGGGDHPLVGRRMP
                     DAELITADGPRRISDCFAGARGLLLLPEQAPTASPLAAWADRVDTLTVKSGGPDADTAH
                     LVRPDGYVAWAGEPARTEELHHAATTWFGAAA"
     gene            24756..25790
                     /gene="ctcO"
     CDS             24756..25790
                     /codon_start=1
                     /gene="ctcO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:O-methyltransferase (Score: 240.2; E-value:
                     5.9e-73)"
                     /gene_functions="biosynthetic-additional (t2pks) MET
                     C2O|C2N (Score: 608.8; E-value: 5.6e-186)"
                     /gene_kind="biosynthetic-additional"
                     /product="CtcO"
                     /protein_id="AEI98658.1"
                     /transl_table=11
                     /translation="MTSSTDSAAARARRIVALNTAYFQAKALQSAVELGLFELLAERPA
                     GLDRIRAELGVQHRLFKDFLNALVGLGLLDEQDGGYRASELAREFLLPGPTYLGGTARQ
                     HARLHYHAWAQLTDALRDGKAKSAVAAQGQLAYPKQYEDLDRARQIMLHMDAHNGFTAD
                     ELARAIDWSRYTSFVDVGGGRGNVASRIVTAHPHLRGGVFDLPALRPLFEELVVSAGTA
                     DRVDFHGGDFFATDLPEADVVIFGHVLPDWPVGDRRELLRRAHKAVRPGGLVVLYDAMI
                     DPEERDPEVLLQRINHTMIRDEAGAYSLQEARAYLEEAGFTVDRIAASDTITRDHFAIG
                     VKSV"
     gene            25808..27475
                     /gene="ctcP"
     CDS             25808..27475
                     /codon_start=1
                     /gene="ctcP"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Trp_halogenase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1119:halogenase (Score: 402.8; E-value: 3.5e-122)"
                     /gene_functions="biosynthetic-additional (t2pks) HAL
                     (Score: 740.5; E-value: 1.6e-225)"
                     /gene_kind="biosynthetic-additional"
                     /product="CtcP"
                     /protein_id="AEI98659.1"
                     /sec_met_domain="Trp_halogenase (E-value: 3.7e-10,
                     bitscore: 30.3, seeds: 23, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDTTADQTRHGDRPYDVVIIGSGLSGTMLGSILAKHGFRIMLLD
                     GAHHPRFAVGESTIGQTLVVLRLISDRYGVPEIANLASFQDVLANVSSSHGQKSNFGFM
                     FHRDGEEPDPNETSQFRIPSIVGNAAHFFRQDTDSYMFHAAVRYGCDARQYYRVENIEF
                     DDGGVTVSGADGSTVRARYLVDASGFRSPLARQLGLREEPSRLKHHARSIFTHMVGVDA
                     IDDHVDTPAELRPPVPWNDGTMHHIFERGWMWIIPFNNHPGATNPLCSVGIQLDERRYP
                     ARPDLTPEEEFWSHVDRFPAVQRQLKGARSVREWVRTDRMQYSSSRTVGERWCLMSHAA
                     GFIDPLFSRGLSNTCEIINALSWRLMAALREDDFAVERFAYVEELEQGLLDWNDKLVNN
                     SFISFSHYPLWNSVFRIWASASVIGGKRILNALTRTKETGDDSHCQALDDNPYPGLWCP
                     LDFYKEAFDELTELCEAVDAGRTTAEEAARVLEQRVRESDWMLPALGFNDPDTHHINPT
                     ADKMIRIAEWATGHHRPEIRELLAASAEEVRAAMRVKP"
     gene            complement(27557..28132)
                     /gene="ctcQ"
     CDS             complement(27557..28132)
                     /codon_start=1
                     /gene="ctcQ"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1160:flavin reductase domain protein FMN-binding
                     (Score: 124.5; E-value: 5.2e-38)"
                     /gene_kind="biosynthetic-additional"
                     /product="CtcQ"
                     /protein_id="AEI98660.1"
                     /transl_table=11
                     /translation="MPPEPLSLPLDLAPGLVDGDTFLSIMGALPTGVTVVTTLGPDGEP
                     YGLTCSAACSVSKAPPLLLVCINRDSRVLKALLERGEFAVNVLRGGGESTSARFAAPVD
                     DRFRDVRWEPGSAGGVPVMSADVVAHAECRVAAALDAGDHTIVIGAVVAGGPRPEVPSP
                     LMYWRRSYARWPVEEDPRTAALTLAAEG"
     gene            complement(28350..29882)
                     /gene="ctcR"
     CDS             complement(28350..29882)
                     /codon_start=1
                     /gene="ctcR"
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 348.4; E-value:
                     8e-106)"
                     /gene_kind="transport"
                     /product="CtcR"
                     /protein_id="AEI98661.1"
                     /transl_table=11
                     /translation="MANATSQTGEAVADDAGGPAGFTHRQIITALSGLLLAVLLAALDQ
                     TIVSTALRTIGDQLHGQTVQAWVITGYLVSSTIAMPFYGKLSDIYGRKPLYLAAIAVFI
                     VGSAACAMANSMETLAIARVLQGFGGAGLMSLPTAVIADLAPVRERGRYFSYLMMAWVA
                     ASVLGPLVGGLFAGAGEILGVTGWRWAFLINVPLGLVALVSVRKALNLPHRRVDHPIDF
                     RGALTLALCLVPLLIVAEEGLDWGWGSARSLTLFAVSLIGLVLFVLAERARGLEAMVPL
                     RLFRRGGITMATAVNFTIGVGIFGTVSTLPLFLQLVQGRSATVAGLVIIPVMTGAIVSQ
                     TICAKIIKKWNRYKKPAIVGLGSMAGALLSLSAAGADTPLAVIVVIAAWLGFGIGLSQT
                     VITLAIQSSAPKSELGVANAASGLFRQLGGTSGAAVFMSVLFGVAAGRLDGADPDEAVR
                     RALSDPDSTGGLSASAVDAFTSGFDTMFLVGGLILAVGFLLTFPLRELSDEE"
     gene            30019..30516
                     /gene="ctcS"
     CDS             30019..30516
                     /codon_start=1
                     /gene="ctcS"
                     /gene_functions="regulatory (smcogs) SMCOG1135:MarR family
                     transcriptional regulator (Score: 75.7; E-value: 4.4e-23)"
                     /gene_kind="regulatory"
                     /product="CtcS"
                     /protein_id="AEI98662.1"
                     /transl_table=11
                     /translation="MTDLSPAAETLSDITTELFAVNGALLRAGDALSARFGLTSARWQV
                     LGLLAEGPQSAAHLARERGLRRQAVQQTVVKLVEEGLVSTSPNPADRRAPLVSLTAKGT
                     DALARIEPAERLWMEHLAGGLDPDDLKATLRLLRGLRAVLAEGLPPAAVGGADAADVTG
                     PA"
     gene            complement(30500..32329)
                     /gene="ctcT"
     CDS             complement(30500..32329)
                     /codon_start=1
                     /gene="ctcT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Asn_synthase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177:asparagine synthase (glutamine-hydrolyzing)
                     (Score: 651.3; E-value: 2.3e-197)"
                     /gene_functions="biosynthetic-additional (t2pks) AMID
                     (Score: 1192.5; E-value: 0)"
                     /gene_functions="biosynthetic-additional (t2pks) AMID
                     AEI98663.1_Chlortetracycline_malonamyl-CoA (Score: 1213.0;
                     E-value: 0)"
                     /gene_kind="biosynthetic-additional"
                     /product="CtcT"
                     /protein_id="AEI98663.1"
                     /sec_met_domain="Asn_synthase (E-value: 1.4e-89, bitscore:
                     292.3, seeds: 78, tool: rule-based-clusters)"
                     /sec_met_domain="GATase_7 (E-value: 3.4e-49, bitscore:
                     157.1, seeds: 307, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCGIVGVVDYDAPAEHRRDLLQAMTDTMACRGPDAEGLWFGRAAG
                     LGHRRLSVIDPEHGRQPMTAEHEGRGAAITFSGEIYNFRELRAELTSHGHRFRTSCDTE
                     VVLRGYLQWGAALVERLNGMFAFAVWDEHSEELLLARDRMGVKPLYYWPTAAGVRFGSE
                     PKAVLADRTLPRRVGPDGLCEVLDMVKTPEAAVFSGLVEVRPGQLVRVGRGGVRRQTYW
                     RLEAREHTDDLPTTIGTVRDLLADTVTRQLVSDVPLGTLLSGGLDSSAVTALAARSGPV
                     RSFSVDFRGAADAFASDAVRREADAPYVRELAGHVGADHLEVLLDSPGLSDPAVRSAVL
                     RATDLPPAYWGDMWPSLYLFFRAVRENVTVALSGEAADELFGGYRWFRNPLALRAATFP
                     WLTPGSARYFGGSSLFQPGLLDKLDLDGYRAARYAEALAEVPVLPGESAPERRMREIGH
                     LNLTRFVQTLLDRKDRMSMAVGLEVRVPFCDHRLVEYVFNVPWEMKSFDGREKSLLRAA
                     VADLLPRSVVERVKTPYPATQDPGYEGALRAELAGVLADPDAPVLPLLDRARALAAAAR
                     PTGAVSRPYDRGSLELVLWLNSWLAEYEVTLDL"
     gene            complement(32332..32586)
                     /gene="ctcU"
     CDS             complement(32332..32586)
                     /NRPS_PKS="Domain: ACP (12-77). E-value: 3.5e-15. Score:
                     47.9. Matches aSDomain: nrpspksdomains_ctcU_ACP.1"
                     /codon_start=1
                     /gene="ctcU"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1129:acyl carrier protein (Score: 108.1; E-value:
                     3e-33)"
                     /gene_functions="biosynthetic-additional (t2pks) ACP
                     (Score: 110.7; E-value: 6e-35)"
                     /gene_kind="biosynthetic-additional"
                     /product="CtcU"
                     /protein_id="AEI98664.1"
                     /sec_met_domain="PP-binding (E-value: 1e-11, bitscore:
                     36.5, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEFTLDDLITALKEAAGADEGIALDDILDVPFADLGYDSLALFN
                     TLNTIERERGITLPDETVVEATTPRMLLDAVNLGLATAG"
     aSDomain        complement(32356..32550)
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctcU_ACP.1"
                     /evalue="3.50E-15"
                     /label="ctcU_ACP.1"
                     /locus_tag="ctcU"
                     /protein_end="77"
                     /protein_start="12"
                     /score="47.9"
                     /tool="antismash"
                     /translation="LKEAAGADEGIALDDILDVPFADLGYDSLALFNTLNTIERERGIT
                     LPDETVVEATTPRMLLDAVN"
     gene            complement(32656..33861)
                     /gene="ctcV"
     CDS             complement(32656..33861)
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (66-364). E-value:
                     2.7e-25. Score: 80.9. Matches aSDomain:
                     nrpspksdomains_ctcV_PKS_KS.1"
                     /codon_start=1
                     /gene="ctcV"
                     /gene_functions="biosynthetic (rule-based-clusters) T2PKS:
                     t2clf"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093:Beta-ketoacyl synthase (Score: 634; E-value:
                     1.4e-192)"
                     /gene_functions="biosynthetic-additional (t2pks) CLF 8|9
                     (Score: 672.5; E-value: 4e-205)"
                     /gene_kind="biosynthetic"
                     /product="CtcV"
                     /protein_id="AEI98665.1"
                     /sec_met_domain="t2clf (E-value: 5.3e-200, bitscore: 655.4,
                     seeds: 26, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDVVVTGIGVVAPNGWGVAEYWDATLAGRSGLGPLTRFDSTGYR
                     AHVAGEVNFTPEEHLPGRLLPQTDHMTRLALVAAEEALADAGADPTTMPDFSAGVVTAA
                     SAGGFEFGQKELQALWSKGPAYVSAYQSFAWFYPVNTGQISIRHGMRGPGSALVAEQAG
                     GLDALAKARRHVREGTALMLAGAVDGSLCPWSWLCLSRSGTVSPRRDPQRAFLPFDADA
                     SGGVPGEGGALLVLETPDGAAERGQHRHYGRIAGYAATFDPRPGSGRPPGLRRAIDTAL
                     ADAGIGPSDVDVVFADASGVAERDRAEAEVLGAVFGPRGVPVTAPKTMTGRLLAGGAPL
                     DVAAALLSLRDGVIPPSVHIGRPAHPDLDLVRDRPRPARLGSALVLARGHGGFNSALVL
                     TS"
     aSDomain        complement(32770..33663)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctcV_PKS_KS.1"
                     /domain_subtype="Modular-KS"
                     /evalue="2.70E-25"
                     /label="ctcV_PKS_KS.1"
                     /locus_tag="ctcV"
                     /protein_end="364"
                     /protein_start="66"
                     /score="80.9"
                     /tool="antismash"
                     /translation="QTDHMTRLALVAAEEALADAGADPTTMPDFSAGVVTAASAGGFEF
                     GQKELQALWSKGPAYVSAYQSFAWFYPVNTGQISIRHGMRGPGSALVAEQAGGLDALAK
                     ARRHVREGTALMLAGAVDGSLCPWSWLCLSRSGTVSPRRDPQRAFLPFDADASGGVPGE
                     GGALLVLETPDGAAERGQHRHYGRIAGYAATFDPRPGSGRPPGLRRAIDTALADAGIGP
                     SDVDVVFADASGVAERDRAEAEVLGAVFGPRGVPVTAPKTMTGRLLAGGAPLDVAAALL
                     SLRDGVIPPSVHIGRPA"
     CDS_motif       complement(32956..32976)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctcV_0002"
                     /evalue="9.90E+01"
                     /label="PKSI-KS_m4"
                     /locus_tag="ctcV"
                     /protein_end="302"
                     /protein_start="295"
                     /score="-3.1"
                     /tool="antismash"
                     /translation="ADASGVA"
     CDS_motif       complement(33172..33210)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctcV_0001"
                     /evalue="1.10E-02"
                     /label="PKSI-KS_m4"
                     /locus_tag="ctcV"
                     /protein_end="230"
                     /protein_start="217"
                     /score="9.2"
                     /tool="antismash"
                     /translation="FDADASGGVPGEG"
     gene            complement(33858..35141)
                     /gene="ctcW"
     CDS             complement(33858..35141)
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (10-420). E-value:
                     2.1e-47. Score: 153.8. Matches aSDomain:
                     nrpspksdomains_ctcW_PKS_KS.1"
                     /codon_start=1
                     /gene="ctcW"
                     /gene_functions="biosynthetic (rule-based-clusters) T2PKS:
                     t2ks"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 451.9; E-value:
                     3.7e-137)"
                     /gene_functions="biosynthetic-additional (t2pks) KS (Score:
                     745.5; E-value: 3.5e-227)"
                     /gene_kind="biosynthetic"
                     /product="CtcW"
                     /protein_id="AEI98666.1"
                     /sec_met_domain="t2ks (E-value: 4.8e-232, bitscore: 761.4,
                     seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVGVDDGRRRVVVTGIGVVAPGEVGTKAFWELLTAGRTATRTIST
                     FDPSPFRSRVAAECDFDPQAAGLTQRQIRQWDRTAQFAVVAAREALDDSGVSGVNDPIR
                     TGVMAGTACGMTISLDREFAVVSDEGRERLVDDAHGVPYLYDYFVPSSMATELAWLVEA
                     EGPVGVVSTGCTSGIDVIAHACDLIRDDAADVMLAGASDAAISPITVACFDAIKATTPR
                     NDEPESASRPFDLTRNGFALGEGAAMFVLEEREHAIRRGAHIYAEVTGYAGRCNSYSMT
                     GLRVDGNEMAEAIRVALDRSRMNPEDIGYVNAHGSATKQNDRHETAAFKKSLGDHAYRV
                     PVSSIKSMIGHSLGAVCALEFAASALAIEHSVVPPTANLHVPDPECDLDYVPLVAREQR
                     VRTVLSVASGFGGFQSAIVLAEPEWSRG"
     aSDomain        complement(33882..35111)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctcW_PKS_KS.1"
                     /domain_subtype="Iterative-KS"
                     /evalue="2.10E-47"
                     /label="ctcW_PKS_KS.1"
                     /locus_tag="ctcW"
                     /protein_end="420"
                     /protein_start="10"
                     /score="153.8"
                     /tool="antismash"
                     /translation="VVVTGIGVVAPGEVGTKAFWELLTAGRTATRTISTFDPSPFRSRV
                     AAECDFDPQAAGLTQRQIRQWDRTAQFAVVAAREALDDSGVSGVNDPIRTGVMAGTACG
                     MTISLDREFAVVSDEGRERLVDDAHGVPYLYDYFVPSSMATELAWLVEAEGPVGVVSTG
                     CTSGIDVIAHACDLIRDDAADVMLAGASDAAISPITVACFDAIKATTPRNDEPESASRP
                     FDLTRNGFALGEGAAMFVLEEREHAIRRGAHIYAEVTGYAGRCNSYSMTGLRVDGNEMA
                     EAIRVALDRSRMNPEDIGYVNAHGSATKQNDRHETAAFKKSLGDHAYRVPVSSIKSMIG
                     HSLGAVCALEFAASALAIEHSVVPPTANLHVPDPECDLDYVPLVAREQRVRTVLSVASG
                     FGGFQSAIVLA"
     CDS_motif       complement(34053..34097)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctcW_0001"
                     /evalue="7.90E-04"
                     /label="NRPS-te1"
                     /locus_tag="ctcW"
                     /protein_end="363"
                     /protein_start="348"
                     /score="12.1"
                     /tool="antismash"
                     /translation="IGHSLGAVCALEFAA"
     gene            35422..36666
                     /gene="ctcX"
     CDS             35422..36666
                     /codon_start=1
                     /gene="ctcX"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050:monooxygenase FAD-binding (Score: 233.2; E-value:
                     1.1e-70)"
                     /gene_functions="biosynthetic-additional (t2pks) OXY
                     (Score: 208.2; E-value: 5.4e-64)"
                     /gene_kind="biosynthetic-additional"
                     /product="CtcX"
                     /protein_id="AEI98667.1"
                     /transl_table=11
                     /translation="MDIDTDICVVGGGPAGLTLALLLVRSGLRVTVLERSRSLDRAYRG
                     EILQPGGQALLDELGVLGPARAHGAVEHDRFLLEEHGRVLIDGDYRRLPGPYNCLLSLP
                     QRHLLTELLAACERHEGFRQFAGTKATALIEEGGFVRGVVAGGAGGSPDRVVRARCVVA
                     ADGRFSKVRSLAGIGYRRQELFSQDVLWFRLSAPPRTDTRRPCDVRVFRAGGNPVLSYR
                     SVPEALQLGWTLPHGGFRKLADRGIGHIVDQLVDAAPEYADLIRQEITGFGDVSLLDVF
                     SGSAEHWVRDGLLLIGDAAHTHSPIGAQGINLAVRDAVAAHPVLVEAVRGGDAGAARLA
                     PYERQRRPEVERITRIQQVQSRMMLSTGRISSTVRPRAAALVSRTPLYGAMLRRIAFGT
                     APVRLRADLLAGAGR"
     gene            36663..37985
                     /gene="ctcY"
     CDS             36663..37985
                     /codon_start=1
                     /gene="ctcY"
                     /gene_functions="transport (smcogs)
                     SMCOG1117:sodium/hydrogen exchanger (Score: 384.8; E-value:
                     7.1e-117)"
                     /gene_kind="transport"
                     /product="CtcY"
                     /protein_id="AEI98668.1"
                     /transl_table=11
                     /translation="MSGGAAIAAGDSATASGVLLALAVVLASAFVCGRIAARVRQPVVM
                     GEIVGGVALGPSLLGLLPGHLDASLFPAEVQSYLRVLSQLGLVLFMFTVGLRFDVGHLR
                     GAGRRVTAVSLSSVALPFALGVGLAVLLYPWFDKAQLSTDGRLGPALFLGAAMSITAFP
                     VLARIIAERRMQHDPLGSLSLACAAFQDFLAWCALAVVVAVVEAKGLWSLGRLALDTAV
                     VVLVLVGVVRPLLSRLLAPGRRRPLPRPWIHAVLVTGTLVTAWVTAEIGLDAVFGAFMF
                     GAAVPRDRIEAIAPDVPEQIERAGLLLLPAFFAVTGLAVDLTGLGLRGLAVVAAVLVAA
                     CAGKFVGAVAAARATGSSRREARVLGILLNARGLTELVILNVGHRLGVIDTRMFTAMVV
                     MALVTTLMTGPLLERHAAGSAGSATLPDPAPEAAQASRAPS"
     gene            complement(38489..39532)
                     /gene="ctcZ"
     CDS             complement(38489..39532)
                     /codon_start=1
                     /gene="ctcZ"
                     /product="CtcZ"
                     /protein_id="AEI98669.1"
                     /transl_table=11
                     /translation="MAQADSTERTTVPEDAGTPADRTGGFLGLRHWGPDARGGNTWRRG
                     LVIALLALLTAVLLAFHAEMPNSVGNLGSLLETFLPWVGLAVPVLLVPALLRRSATALL
                     ALLVPAVLWANLFGGLVSDKSGGTGDWTVVTHNVEAGNTDVPGTIRGLVASDAQIVALQ
                     ELAGNQLRSYETGLAGAYPHHTVEGTVGLWSKYPIGEVSPVDLKIGWTRAFRARVTTPQ
                     GPVAVYVAHLPSVRLKAESGFTAHQRDVSAQALGDAIQAEPVKKVLLLGDLNGTMNDRS
                     LAPVTSQMRSAQGAAGDGFGFSWPAAFPMARIDQIMSKGGLKPVDSRTLPRDGSDHLAV
                     AATYRYQ"
     gene            complement(39757..40455)
                     /gene="ctc1"
     CDS             complement(39757..40455)
                     /codon_start=1
                     /gene="ctc1"
                     /gene_functions="regulatory (smcogs) SMCOG1224:TetR family
                     transcriptional regulator (Score: 137; E-value: 1.1e-41)"
                     /gene_kind="regulatory"
                     /product="Ctc1"
                     /protein_id="AEI98670.1"
                     /transl_table=11
                     /translation="MDPIDRHTTAPAGPGPSEGETAGMRTDTPSADTGQPCAAVRRGRP
                     RSEAAEQAIFTAVEDLMADGNTLSELTIEGIATAAGVGKATIYRRWPNKEALLVDVVSR
                     LEEPIPAPTGGGAREDLIAMVDYIRRRGLAKRTRWVLKAALGQMQTLPELYTAYRERVI
                     RPRREVGLHLIRRAVAEGVIRDDLDVELLGDLLMGPILYRSILSEDSDLEDPELSRKLV
                     DSVLDGVAPR"
     CDS             complement(40576..>41528)
                     /codon_start=3
                     /gene="ctc2"
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 163; E-value:
                     1.4e-49)"
                     /gene_kind="transport"
                     /product="Ctc2"
                     /protein_id="AEI98671.1"
                     /transl_table=11
                     /translation="ALIYGIIKGGELADFTAFAAWGPTLLGVVALAAFVLYERRIPFPA
                     LDVTWFRNKVFSASVVVVGVIFFALMGVSFFGVFYIQSVRGYSALQAGLLMLPLAVAQL
                     LFAPRARLVVERLGVAATAAGGMVLVALGFVGYTVLTATTPIWVLIVLGLVMGTGMAHV
                     MPPVTVAIMGSLPREKAGAGSAVNNTFRQVGGSLGVAVLGAVLSTVYRDGMTDTLTHLP
                     EGLRDKAGESLEATLAIADRLPNGAGKALIAPANDAFIHAMHVVAALSVGISLVGALVA
                     WFLLPRRAAAPAAGPGGPGAPEQQDRAREAAAAEA"
     gene            complement(40576..>41528)
                     /gene="ctc2"
ORIGIN
        1 accccgagca gccggtcgcg cagcggcttg gaagtggtga gggtgtcgcg cagggtgtgc
       61 cgctcggatt cgtcggcggc ctccagcagc cgggccaggc ccagcagcgc gaggtcgggg
      121 tcggcggtgg cgccgagcgc gtccagcagc accgggtcgt cggccaggcc ctccaggccg
      181 ggcccgtcca gtagccgcac ggccttggcg gggtcggtga acccccgccg aaccagcctg
      241 atctcgggcc ggctgacccg gctcccggcc cgctgctcct ccaccgccat cgctctcccg
      301 gaacgcccag tggcccacgc ggtcacgcgg ccctgaacct accttcccag gagctggtcc
      361 gcccgcgcca cggggcccgc ggcgcgggcg gtcgttccgg cgtcacgccc gttccggcat
      421 ccggttcacc aggtgccaga gcagggccga cagcagcacc gaaccggtcg cggcggcgcc
      481 cgtcaggaac aggtactccc gggcgagcac gcggccggag agcgcgccga cgagccccgc
      541 gcccgcaccc gtcagggcga gtacgaaccg tcttcgttcc gacatccggg tgatctccct
      601 ccggcggccc tggcggcccg tccaggagat cagatgtcgg cccaggaccc attcccggaa
      661 catcacccag agggagacga cggtgcccat ggtacccacg acgagatatg ccggataaca
      721 ggtgagagtt cgccggatcc cgatttgcag ggcggccgtc ccgaaagtca gcgccaccat
      781 catcaggaac cacagaccca tccaccggaa tgcatcgaaa tgggtgaatc tggtggccag
      841 ctgataaagc agcgagaggt atccggaagc catcaggacg ctgtccacga gcatcgcgcc
      901 gaatacccgg gtaaagcccc agctgtggag gaacagactg cggtgcttgt acagcgcctg
      961 cgcccagccg gccgcccacc ggtgggtctg cgcccagtag acggaccagc tgccggggtc
     1021 ccggacgcac acgtacgcgc cgggcacgaa gcccgccttg tgtccggcgc ggttcatctt
     1081 gagcgccagc tcgacgtcct cgcagaggct gtcggcggac cagccgccga ccgcccggac
     1141 cgactccgtg cggtacacgc ccgcacagcc ggagagcacg gcgacccagc cgtgccacga
     1201 ctcgaccgtc cgggacatcc ggtgggccgc ggcccactcg atcacacgcg aacgctggaa
     1261 cacgcccttc acgctgtgcg gcgtgaccga catgcagacg ccgccgtagc ccttggcgcg
     1321 catccgctcc aggcacatct ccagcgcccg gtccgaggcg aagtagccgt ccgcgtcgag
     1381 cagggcgacg aattcggtgg tcacctccgc gagtgcgagg ttgagcgact ccggcttgct
     1441 cctgcagtcg acctccagca cctcggcgcc gcaccgccgg gcgatcgccg ccgtgccgtc
     1501 cgtgcaggag tccgcgagga ccagcacggt gcgcggccgt accgtctggc cgaaggcgga
     1561 cttcaccgcg tcagcgatga agtccgcctc gttgtgtgcc gggatcagca cggtcagtga
     1621 ttcggtcacc gccgggcgag ccacttcacg gccgcgccga tcgcggcggc ggcgccgccg
     1681 gtcgccagga gcgccagcga agcgacgccg gtgtgagcga gtccgtacat aactgttcct
     1741 cactgactgg tcagaattgc cgatcggtga attcatgcgg aattcgaagg aattccctga
     1801 catcgggcca ccgccataac ccgcttttct tctatcacga ccggagtcct taacacgcca
     1861 ttccgggccc cgccggtcga tgcgtccacc ctgaattcat ccggtcggct ccgcccgtgg
     1921 cgcggccgga cggcccggcg tggatcgtgg acggcatggc tatccgattg ctggtggcgc
     1981 tggcgatggc ggcgacgacc gccgcgacgt cggccgccgt ccccgccccc gcccccgccg
     2041 cggccgcggc tccgcggacg cagcgcacca ccgtcctgct ggaccggttc gacaccctgg
     2101 acctgggacc gggccggcgg tggggctggc agaccgccgc gtacgccgac tgcacctaca
     2161 accccaacag ttggaaactc gaccggctga ccaccgacgc gttgagcacg gccgacgggc
     2221 acctgaccgt caccgcccag caccgcgcgg acgggaactg gaacaccggg ctgctgacca
     2281 ccggcgactc ctgtgactcc ggcggcagcg ggttccagct ccgcaccggc gacctggtgg
     2341 tggtgcacgt ccggctcccc gccgcgggca ccgccgcctg gccctgcctg tggacctggc
     2401 gggacggcgg caacgaactc gacctcttcg agtggtacgc cgaccacccg gaccggatcg
     2461 agttcgtcaa ccacgtgcgg gagaacggca ccgtctacta cggcccggac atcggccccg
     2521 agcggtgggt gtacgtggcc gtcaggctcg gcaccgacaa cgacacctgg tacgtcggat
     2581 cctcccggga ccagctgaac ccggtgtggt ccgacgggac gggcgtcggg ccggacttct
     2641 ccgcctacct gatcctcagc ctctcgatcg gcgacgggac gttccacgcc ccgccgaccc
     2701 gcaccgaccc ggtcaccatg gaggtcgacc tgctgagcgt cgaacgaccc tagggacccc
     2761 gaccgcacgg tccggacggg ccccgctcag cgcagctccg ccggcggcac ccgcccgggc
     2821 gtcatcgcct cttcccggac caggctcccc cagaccacca gccggtacag cgaggtgtac
     2881 tccggcgtgc aggtcgtcag cgtgatgtag cgccccggcg aacggtacgg cgaaccggtg
     2941 ggaacgggcg cgatcacgcc cacgtcgtcc ggggaggtct ccggcagcac gccgtcgacc
     3001 cggtagacgt accagcggtc cctggtctcg accaccacgg gggcgcccgg gccgacctgg
     3061 tccaggtcgt ggaacttggc gccgtggccg tcgcgatgtg ccgcgagggc gaagttgccc
     3121 tcgccctccc acggcggaac cgagcggtac ggcacggtgt acgcgccggc cacgccatcc
     3181 gccagggtcg cctcgtccgt accggacctg atcagcacct cgtagtcccg gcccatcgcg
     3241 ggtacgtgca ggaagccgag gtcgccccgg ccgagcccgg ccaccgggga gtccgcgtcc
     3301 gccgcgggcg gcgcggcggc cgaccagctg tcgcgcagcc gcccggcggc ccggtccgcc
     3361 gcccggtccg acaccacgtt gctccaccag agcacgtaca ccgcgaagag gagcaccagg
     3421 agaccgaagg tcaacagccc gtccccggtc caccgggcca ccgcccgcac caccacgccc
     3481 cgttgccgcg ccatcccggg ctcccgtcgc cgccaccgaa ccggccgcca cttcagcgcc
     3541 ccgccccacc cgaccgcaag cggacacact ccggggcgac gcccgtcccc cggacgcagt
     3601 aacgccgggg ccgccaccgg gggtcgccgc cgggaacgcg cggaggcccg cccgacggcc
     3661 gtcgccgggc gggcctcctg cggcagcccc tcagagcacc tggaggttct tgcgcagctc
     3721 gaacggcgtc acctcggagc ggtactcctc ccactcctgg cgcttgttgc gcaggaagaa
     3781 gtcgaagacg tgctcgccca gggtctcggc gaccagttcg ctgcgctgca tcaggtcgat
     3841 ggcctcgccg aggttctgcg gcatcggctg gatgccgagg gcgcggcgct cggagtcggt
     3901 cagggcccac acgtcgtcgt cggcgccggg cgggagctcg tagccctcct cgatgccctt
     3961 gaggccggcc gcgagggtga cggcgtaggc gaggtacggg ttgcagccgg tgtccaggga
     4021 gcggacctcg atccgggtgg agccctgctt gcccggcttg tacatcggca cccggatcag
     4081 cgcggagcgg ttgttgtggc cccagcagat gtaggagggg gcctcgccgc cggcgccggc
     4141 ggtgcgctgg gagccgcccc agatgcgctt gtaggagttc acccactggt tggtgacggc
     4201 ggccgtctcg gcggcgtgcc gcagcaggcc ggcgatgaac gatctgccga ccttggagag
     4261 ctggtactcg gcgccggact cgtggaaggc gttgcggtcg ccctcgaaca gcgagacgtg
     4321 ggtgtgcatg ccgctgccgg ggtgctcgga gaagggcttg ggcatgaagc tcgcgtgcac
     4381 gccctgctcc agcgcgacct ccttcatgac cagccggaag gtcatgatgt tgtcggcggt
     4441 ggacagcgcg tcggcgtagc gcaggtcgat ctcctgctgg ccgggggcac cctcgtggtg
     4501 cgagaactcg accgagatgc ccatcgactc cagcatggtg atcgcctggc ggcggaagtc
     4561 gtggcccacc ccgcgcgggg tgtggtcgaa gtagccggac tggtcggcgg ggatcggcgc
     4621 ggtgccgtca ccgggcaggt tcttcagcag gaagaactcg atctcggggt gggtgtagaa
     4681 ggtgaagccc aggtcggagg ccttctccag ggtgcgcttg agcacgaacc tggggtcggc
     4741 gtaggagggc gagccgtccg gcatcaggat gtcgcagaac atccgcgcgg tgcccggggt
     4801 ctcggagcgc cacggcagga tctggaaggt ggtcggatcc ggcttggcga tcatgtcgga
     4861 ctcgtacacc cgggcgaacc cctcgatcgc cgagccgtcg aaccctatgc cctcctcgaa
     4921 ggcctgctcc aactcggccg gcgccaccgc gaccgacttc aggaacccga ggacatcggt
     4981 gaaccacagc cggacgaacc ggatgtcacg ctcttcgagc gtgcgaagca cgaactgctg
     5041 ctgcttgccc atggggacag tctcacctct gctctttacg ctcgtgttac gccccgaagg
     5101 cccccgagag accccgcgga gcggctgccc ccatcatggc cgatcaccgg cctccgcggc
     5161 agggccgacc cctcacgggc tcgcccccgc agcacattgc gtcagttaga cgattacact
     5221 tcgaggcatg cccaatctcc gtgtcgccct gtgccagatc gacccctggg tcggtgacct
     5281 cacccgcaac ggcgacgagg tggtgcgctg gacgaagcag gccgtggagg ccggcgccca
     5341 gctggtcgcg ttccccgaga tggtcctgac cgggtacccg gtcgaggacc tcgcgctgcg
     5401 ccgctccttc gtcgaggcct cgcgcggcgc cctggtcgag ctggcgggcc ggctggccga
     5461 cgacggcctg ggcggggtgc ccgtggtggt cggctacctc gggcgctccg agcacgcctc
     5521 gccgcgcttc ggccggcccg ccgggtcacc gcagaactgc gccgcggtgc tgtaccgggg
     5581 cgaggtggtc acccgcttcg ccaagcacca cctgcccaac tacggcgtct tcgacgagtt
     5641 ccgctggttc gtcccgggcg accagctgcc cgtgctgcgg ctgcacgggg tggacgtcgc
     5701 gctggcgatc tgcgaggaca tctggcagga cggcggccgg gtcaccgccg cccgggaggc
     5761 cggggccggg ctgctgctgg tggtcaacgg ctcgccgtac gagcggaaca aggacgacct
     5821 gcggctcgag ctggtgcgcc gccgagcggt cgaggcgggc tgcgccctgg cgtacgtcaa
     5881 catggtcggc ggccaggacg agctggtctt cgacggtgac tcgatcgtgg tcgacgcgga
     5941 cggccgggtc ctggcccgct ccccgcagtt cgaggagcac ctgctggtgc tggacctcga
     6001 cctgccggcc gcgagcagcg accacaccga cggcctgttg ctgagcgacg gactgcacct
     6061 ggtccgcacc gagctgggtg acgagccgtc gcccgccccc gcggacaggc tcaccgccgg
     6121 gatcgcgccg cggctgtccg acgaggccga gatctgggcc gcgctggtct ccggcacccg
     6181 ggcgtacgtg gtcaagaacg gcttcgaatc cgtgctcatc ggcctctccg gcggcatcga
     6241 ctcggcgctg gtggccgcga tcgcggtgga cgcgatcggc gccgggaacg tgcactgcgt
     6301 ctcgatgccg agccgctact cctcccagca ctcccgagac gacgcggccg aactggcccg
     6361 ccgcaccggg ctgcacttcc ggaccgtctc catcgccccg atgttcgacg cctacctggg
     6421 cgccaccgaa ctgaccgggc tggccgagga gaacctgcag tcccggctgc gcggcaccct
     6481 gctgatggcg atctccaacc aggaggggca catcgtgctc gcgcccggca acaagagcga
     6541 gctggcggtc ggctactcga ccctgtacgg cgactcggtg ggcgcgttcg gcccgatcaa
     6601 ggacgtctac aagtcgctcg tcttccgcct cgcccgctgg cgcaacgagg aggccgagcg
     6661 gcgcggcgag gtgccgccga tcccggagaa caccatcacc aagccgccgt ccgccgagct
     6721 gcggccggac caggtggaca ccgactcgct gccggactac gacctgctgg acagcgtgct
     6781 ggaccgctac atcgagggcg acgagggccg ggacgcgatc gtcgcggccg gtttcgaccc
     6841 ggcggtggtg gaccgggtgg tccggctggt cgacaccgcc gagtacaagc ggcgccagta
     6901 cccgccgggc ccgaagatct cggtcaagaa cttcggccgg gaccgccgcc tgccgatcac
     6961 caaccgctgg cggcgcggct aggagcgtgt ctcagtaacg gggcacccgc ctgagtctcg
     7021 tgatctttcg tgcgggatga tcctgatatg cgtggtgagg atgggctgtt cgagatcgag
     7081 ccggtcgagg tgaagcggac gccgggtcgt ccggcagcgg tggacaagac gttccggacg
     7141 ttcgatccgc atcaggtcct gctgctgccg ccgtctctgg acgactggct gcccgagggc
     7201 cacctcgccc ggttcgtggc ggacctggtc gacgaggtac tcgacctctc cccgatcctg
     7261 gccgactaca ccgagaagcg gggctacccg ccgtatgacc ccaggctgat ggtgcgcctg
     7321 ctgatctacg gctacaccac cggcgtccgc tcctcgcggg cgatcgaacg caagtgctcc
     7381 gacgacgtcg cgttccggtt cctggccgcc gaccagaccc cggacttccg ctcgatcgcc
     7441 cggttccgcc gccgccacct cgatgccctg gccgacctgt tcacccagtc gctgcacctc
     7501 gcgaccaagc tcggcatggt caagatgggc cgcgtagccc tggatggcac caagctcgaa
     7561 gcgaacgcct ccaagcacaa ggcgatgagc tacggccgcc tcatcgacaa ggaagagcag
     7621 gtcgaggccg agatcgccgc gctggaggcg aaggccgcag ccctgctcgc cgacgccgag
     7681 gccaccgacg aagccgagga cgccaccttc ggcgtcgacg gcaaggacat ggacctgccc
     7741 gccgaactcg accggcgcga gaagcgcctc gccaggctgc aggccgcccg cgcccagatc
     7801 gaggccgagg ccgccgacaa ggcccgccgc cacgccgagg acaaggaacg ccgccgccgg
     7861 cagcgcaccg gcaccaacga ccagcaggcc gtcatcgacg ccggcgaggc cgccgccgcc
     7921 aaggcccggc cgaaaccgaa ggcccaggcc aacttcaccg accccgactc tcggatcatg
     7981 aagaacagcg acggcgccta catccaggcc tacaacgccc aggccgtcgt ggacgaggcc
     8041 ctccaggtca tcaccgccgc cgacgtgatg accaacgcct ccgacgcgct gaactacacc
     8101 acgatgctcg accagtccgc gcagaacacc ggccgccacc ccaagcaggc cctcgtcgac
     8161 gccggctact gctccgagac caacctcgaa gccgcacggg agcgccaact ggcctgcggc
     8221 accgacacgt tcatggccac cggccggctc ggccacgacg aacaggtcca acccgcacca
     8281 cgcggacgca tccccaagga cgcgaccctg aaggagcgca tggcccgcaa gctgcggacc
     8341 aagcccggcc ggaaggccta cagccgccgc aaggccatcg tcgaacccgt cttcggacag
     8401 atcacgacct gccagaacgg ccgccagctc ctcctgcgcg gcgaggacgg cgcccgcggc
     8461 gagtggcgcc tgctcgccgc ctgccacaac ctccgcaaga tcttccgcca cgccgggacg
     8521 gcagggatcg ccgctctggc cggctgacca gccgggcctc cccggccgcg tcacgagccc
     8581 tgacagccgg acacccggcg ggcaggcccc cgccacagcc ccacacaggc cccggcggag
     8641 ccgccgcccc gccggtcacg cgagcggagc cgcttgctcg ttactgaccc acgctcctag
     8701 gggtcgtccg gccggaacga cggctcacgt tccccggcgc acgcaccgtg gtgcgtgcca
     8761 tcacacctcc ggcagcgccg tgcccgggcg cgtcgtgctg ccttcggcgc cacattcccg
     8821 gtcgccccgc cggatcttga cgaggagtca cggcggacgg tgccgaagaa cttctggatg
     8881 tgggatcgac cacccggtcc ttcacgtgat tcccgcaggt ttggtcagcc ggccgtcgac
     8941 cggcgggatc cggacacccc cggccgacat ccggctcccc tcccccggtt ccgaagtcgc
     9001 caatcaccgg cggccggatt tgtccgacgt taccccggtc acatgcgcgg agagcgagat
     9061 cgtcccgtga tctagcgtcg ttcgtgcggc gaaaaaccgc ccttgggcgg aaagtaagaa
     9121 tcgggttagg ttctcctcag cccgggtcgc gaacgaaccg agccacccgg gcggcggggc
     9181 gggtgaccgg cggccgccgc gggcgggccc ggatcgtgaa ccccggccgg ccgcgtgtgt
     9241 ggcggcccgg aagccgcccg gccgtgcctt cctcacacgc gacaacgaac acgtacacct
     9301 acccgaccgc cacccaccgg aggacttcgc atggctgctt tccccggccg gccagaggcc
     9361 tcacgccagt tcacgggcgt ggccgcaccg gcccgtgccg cggccgcccg atcggccgac
     9421 ggctccagga cagcccgggc cgtcccggcc cccgcggcac ggcccacccc gcagcgaccc
     9481 cggcccggcc gctccacggc ccggtcccgg cccgcacacc ctccgggccc cactccgaag
     9541 aatcggttct cttgggcccg ccaccgggcc cggggcgtcc accgcaccgc ccgccgcggc
     9601 cagcccggat cgctccactc atcggtcact cgcgcctgtc gccatcgggg gtcaaccgtg
     9661 tcagtcggca acaaccatcc gtcggttctc gtcgtcgagg acaacgtcct gctgcgcacg
     9721 ggcctgcagg ccctgctgtc ggccgagccc gacctcgtcc tccgcgccgc cgtcggcggc
     9781 gtggacgaag cactcgccgt catggccggg caccccgtgg acgtcgtggt gtacggagcg
     9841 ggcgagtcgg tggccgacac cgagcggggc ctcgagcgcc tgctcgaccg gggcacccgg
     9901 gtggtcgtac tgagccggcg ggaccacccc ggcgagatgg agacgtacct cagcagcggt
     9961 gtgcacgcct acctggccga ggacgcggcc ggggagtgcc tcggcttggt gatccggggc
    10021 ctgacctcgg accgggagcg ggtctacatc atggcctcgc gctccggcct cgactggatg
    10081 gccggccagc gcggcaaccg cctgtccgga cgcgagcggg aggtcatggg cctggtcgcg
    10141 aacgggctga gcaactcggc catcgcgggc cggctctgca tctcgcccgg caccgtcaag
    10201 cgccatctcc ggaacgtgtt cgtcaagctc aacgccgtct cccggatcga cgccgtgaac
    10261 aaggcccggg ccgcttccat gctggtcccg gccggccggg cctgagcccc gcggaccggt
    10321 ccggcgcgga tccgtccgcg gtgaccggtc cggcgcggac ccctgcgggg acgacggccc
    10381 cggcagggag cggagcaggg ctcggccggg acgggcctca ggccgaacgg gcccgcaggc
    10441 cctgctccat cgcccgcgcg gcaagcgcct ggaactcctg ccgagtgggc gacgtgccgc
    10501 tgagcaggtc gttgtgcagc tcctgcagcg gtcgggaggg ggcgatgccg aggtcctcgt
    10561 cgagtcggcg gtagagcacg cggtagacgt gcagggcctc gctccgccgc ccggcggcgt
    10621 ccagggcgag catgagctgc tcgtggtacc actcgttcat cggctggtgc agggtcaaca
    10681 gtctcagttc ggggatgagt tcccggtgtc gcccgagctg ccggtcggcc aggatgcggt
    10741 gctccagggc gcgcaggcgc atctcctcca ggacggcgac gtgaccggcg agcggagcac
    10801 ccaccgggat gtccgccagg gcggtgcccc gccacaggtc cagcgcctgc cgcagccgct
    10861 gggcggccgc ctcggggtgg ccggcgacca gcagtcggtc cccctcgtgg tgcagccgct
    10921 cgaactcctg ggcgtccagc tcctcctccc ccagcagcag cacgtagccg ggggccttgg
    10981 tgaggatgac ctcgcggccc agcggacggc agagcttgcg cagttggtag atgtacgtct
    11041 gcgcggtggt gaccaccgtg cgtggcgggc tgctgcccca gatctcctcg atgatgaggc
    11101 cgaggtccac gatccggttc gcgttcatga gcaggaccgc cagcgtccag cggaccttca
    11161 gcgcgctcgg ggtgcacgga attcccttgt cgaggacttc cagcggaccc agaatgttga
    11221 acttcaccat gcctccgatg tcgctcggat ttccctcggc cccaggtata tccgggtccg
    11281 cggacgggcc tcaagaggaa tccgcacaag gtggcaggcg cgcaattcca aggtggcacc
    11341 gacgcatttc cagagcggtc cggctccctg tcccgaggga aacacccccg ccgaccgacc
    11401 cccgccgatc ggctggcgga tcgacaagtc ctgttaggct gggggcggtt ggccccatgg
    11461 gccggcaccg gtcacctgat acccgcgaga cagagccacg aggagaagga cgtgccccga
    11521 aagatccgtg ttgctccggt aatccgtacg aagaccgcag aactagggga cacacgtctt
    11581 gacaaccgtg aacatcggaa tcctggccca tgtcgacgcc ggtaagacca gcctgaccga
    11641 gcggctgctg cacaccgccg gcgtcatcga ccgggtcggc agcgtcgacc gcggcgacac
    11701 ccagaccgac tcgcacgaac tcgagcgcca gcgcggcatc accatccggt ccgcggtggt
    11761 gtccttcacc gtgggcgacg tcaaggtcaa cctcatcgac acccccggcc acccggactt
    11821 catctccgag gtggaacggg ccctcggcgt gctcgacggc gtggtgctgg tcatctccgc
    11881 cgtggagggc gtgcaggccc agacccggct gctgatgcgc acgctggtga aactgcgcat
    11941 gccggtcatc ctcttcgtca acaagatcga caggatgggc gcgcgctacc acgagctcct
    12001 ggacgagatc cgctccgagc tcaccccggc cgtcgtcgcc ctgacccggg tcgaagggcc
    12061 gggcaccccc ggagcacggg cgttcgcccg gaccgtcggg accgacgacc ccgacttcgc
    12121 cgccgaactg gccgacatcc tggccgagca cggcgacgac ttcctggccc gctacctcga
    12181 ggacgagacc tccctgaccg cgcaggacta cagcgcggaa ctcgcccgcc aggcggcccg
    12241 gggccagctc tacccggtgc tcttcggctc ggccgtggcc ggcgtcggca tcgatgccct
    12301 ggtcgacggg atcaccaggc tgtttccggt caatcacggc ggctccgggg gcaccctccg
    12361 cggtaccgtg ttcaagatcg agcgcgggtg ggcgggcgag aaggtcgcct acgtccggtt
    12421 gcacgggggc gagctcgggt cgcgggagaa ggtgtccgtg ttccggcgcg accagcacgg
    12481 agccgtcacc gagattcccg gccgcaccac ggtggtcgag gtgttcgacc ggggctcggc
    12541 cgtcgtcgag tcgcgggccc gggccgggga catcgccaag gtctgggggc tcaagggcat
    12601 ccggatcggc gaccggctcg gttcggccga ggggctggac ggggagcacc tgttcgcgcc
    12661 gccgagcctg gagaccgtga tccgaccctc ccggcccagc gcgatgcccg aactgtacga
    12721 cgcgctgctg cagttggccg accaggaccc gttcatcaac gtccgcaagg acgacgagga
    12781 gcaggagatc gccgtctcgc tctacggtga ggtgcagaag gaggtcatcg cggccaccct
    12841 cgccgacgag ttcaagctgg acgtggcctt cgagggcacc cggatcatct gtgtcgagcg
    12901 cccgatcggg gtcggcgagt cggtggagga gatcgactac cggagcaaga ccttcttctg
    12961 ggccacgatc ggcctgcggg tggaacccgg ggagccggga tcaggggtcg tgttccgccg
    13021 ctcggtggag ctcggctcgc tgccgcacgc cttccacaag gccgtcgagg aggccgtgcg
    13081 ggccaccctg cagcaggggc tgaacggctg ggaggtgctg gacatcctgg tgaccctcac
    13141 ccgttccggg ttcgccagcc cggtgagcgc ggcgggcgac ttccgcaagc tcacgccgct
    13201 cgtgctgatg aacgcgctca agcaggcggg aacgcaggtg tacgaaccgg tcaaccgctt
    13261 cgagctggag gtgccgggtg agaacgccag cgccgccctg ctgagcctgg tggagtgcgg
    13321 cgccaccccg gagagcaccc ggggcctggg cagcagctgc ctggtggagg ggacgatccc
    13381 ggcccgcacg gtgcaggagt tcgagcagcg gctgccgggc ctgagccagg gccagggcgt
    13441 gctggtcacc cggttccaca gcttccagcc ggtggtcggg gcggcgccga ggcggcggcg
    13501 gaccgacctc aacccggtgg accgctcgga gtacatgctg cgggccttcg gccggatctg
    13561 acggggcgtc gtgaacgctg agggcccgac caccgtgacg gtggccgggc cctcagccgt
    13621 ggcgcactcc gtcctcagtc gagcagcgcc accgctcgcg tccaacccgc ccccgccccg
    13681 gcgatcttga ccgggaacgc ctgcacggtg aacccggtcg gcgcgggcag tgcgcccaga
    13741 ttgctcagac gctcgatctg gcagtactcc cgctgccggc ccgcgaagtg cgcgggccac
    13801 agcacggaac ggtcgcgggt gcgctggaac tcggcgagca tgtgcgtgaa cggagcgtcc
    13861 agcccgaagg cgtccgtccc gatgagccgc acgccgagat cgagcagaag gttcgtcgcc
    13921 gccccgtcca ggcccgcgaa ccgggtgaag tactcgggag tcccggcgag tcgttcggca
    13981 ccggtgtgca gcagcacgat ctccccggcg ctcggccggt ggtcgatctc gtcgaaggcg
    14041 cgccgcagcc ggtccacgcc gaccgtcccg accccgcagt cggtgaggtc cagccggacg
    14101 cccggcccga tgaaccattc cagcggcaac tcgtcgatgt ggcgcggcac tccgtaggcg
    14161 gccctgctgc cgtagtggga gggtgcgtcg acgtgcgtgc cggtgtgggt ggtcagggtc
    14221 agggtgtcca gcgagagcag ttccccgtcc ggcaggtccg cgacgtcgaa ctcgaggccg
    14281 tggtcacgga gcatgccctc ggccatgtgg cgcgcgccgt cggccggcgt cagcacctcg
    14341 tggcggatgc cgtccacctc ccaggcgttg gcgtcgatcg tcgaggagag gtcaatgagg
    14401 cgcatgcgcg gccccttccg gcagcagagc gcagtcccgc aggacgtcga ggcagcgctc
    14461 cggcccccga tcccgcgcgg cgaggtggcc gtccggccgg atcagcagga actcccctgg
    14521 tgccaggccg agttcgcggc gcagcacacc cccggggtcg ggcagctcgc ccggggctcc
    14581 ggggtcggcg acggtacgga cggagacggc ggagccgaac agccgctcca cccgggcgag
    14641 cgcctcccgg tacccggtgc tcccgccctc ggccggggtg gcgagcaggg tccagcgggg
    14701 gtcggcgagt tcggcgcaga gcgcggacca gccggggtgc ccggcggccg tccgggcgtc
    14761 gcagcccacc cggtccccgg gcgagggccg cccggcgcgc gagccggccg ggcgggtgag
    14821 cgggctgtcc gggtaggcga gggccagtcc gcagaagccc cggatcatcc ggccctcgac
    14881 cttgcgccgc agcggcgtga tccggcgcag cgccgcggtg cccacggtca gcagggccgg
    14941 ggccagcgcg gtgcgcagcg acaccagggc ggtggccgtg cgggtggagc gcagcagcac
    15001 ggccccggtc gggactcgct cggcgtcgta gctgtccagc agggcgggcc cggcgtggcc
    15061 gcggatcacg tcggcgagct tccaggcgag gttgtaggcg tcctggatac cgctgttcat
    15121 gccctgcccg gaggccgggc tgtggacgtg ggcggcatcc ccggcgagga agcagcggcc
    15181 ctcgcgcatc cgggtgatct ggcgttgctg gacggtgaag acggagagcc aggtcggggt
    15241 gccgacctgg acggggcgcc cgagcgcccg gccgatcttg tcggccaggc ggcggcggac
    15301 cagctcgcgg tcctcggcgc cgtcggtgtc caccgtgtcc accacgcgcc acttgccggg
    15361 ctcggggaac gggacgagca gcagggtgcc gggctcggtg tgcagcaggt ggttgctgtc
    15421 cggcgggagg tcggcgtcga gggtgacgtc ggcgttgagc cagacctcgg tggagtcgcc
    15481 gatcaggcgc atcccgagct gcttgcgcac ggtgctgcgg ccgccgtcgg cgccgaccag
    15541 ccagggcacc cgggtctcct cggtgcgccc gtcggcgtgg cggagggtga cgagcacgga
    15601 gtcgggcccg gtctgcagcg cggtgagttc gacgccccat tccacgggga cgccgagttc
    15661 ggcggtgcgc tcgcgcagca cctgctcggt gaccacttga tcgaccatca ggctgaacgg
    15721 gtaacgggtc ggaagtgagc ggtagttggt gtcgaagcgg atgagggtgc ggccccggcg
    15781 gtgcatggtg aagtgggtga cccgccggcc gagcggcagc agccggtcga gggcgcccat
    15841 ctgctcgagc acctccatgg tccgggcgtg caccgccagg gcccggctgc tggtggccgg
    15901 gccgggcgcg gcgtcgacca gccggacggg tacgccgcgc ctggcgagtt cgtgggccgt
    15961 ggtgaggccg accgggccgg cccccgcgat caggacggcc ggagcggggt cagccacggc
    16021 gttcctcggc gaagcgcttg gccaggccga gcgtggcgcg gctgttgccg ccggcggcct
    16081 cgcggatgaa gcggcgggcg gtggcggcgg tggcgtccgg gccgaggacg gtggggaccg
    16141 cctcggggtt gaggacgacg gcgtgccagg aggtgacccg cactccgcgg tcggtcggct
    16201 cgacggtcca gcggccggtg tgggcggcca tcatggaggg ggtgcgcagc tgcttgtagg
    16261 cgatgccgga ctccgggaag cagatccgga tggactcggt ggtgtgttcg gagccgtcgg
    16321 cggtgcgggt gtccatggac atgtgctgga tgccgccggc ctcctcgcgc aggtcgaggc
    16381 gggcgacgtg gggcagccgg gcgggccagg cggcggcgtc ccgcaggaag tcgtagacgg
    16441 cctccggggc ggcgtcgacc agcaccgagt cctcgaactc gaactcgaac tcggcgagcc
    16501 ggttccagcg ttcggcgagg tccttgatgc cggcgagttc gctgcggctg ttgcggtccg
    16561 tcgcctcgct gatccagcgc aggccctgcg ggtcgtcgtc gagcgcgctg aactcgtggg
    16621 tgagggtgag ggtggtgccg ccggggcgct cggcgacctg ccactccccc gccatcgagg
    16681 agaccggggc cgaggaggcc tcctggcgga aacggatccg gcgcaggtcg gcgtccaggt
    16741 cgcggcggga cgtccagtgc ttgacctcgc cgttggcccg ggcccagatc ttcaggcgct
    16801 cggcgcccgg ccccagctcc tcgcgctcga cgtggagggt gggggcgaag cgccgcggcc
    16861 aggccagggc gtcggcgatg acggtgtaga cgacctcggc gggggcgtcg acgtcgatcg
    16921 agtgggtggt gtgctggatg gtgctcatgg gtgggaccgg ccctttccgt cggcggggtg
    16981 aagctcggcg gggtgaagtt cggcggggtg aagttcggcg gggtgcgtgg ggtgcggctc
    17041 agtagatgcc gaggccaccg cagacgttga tcgcctgcgc ggtgaccgac gcggcgtcgg
    17101 gggtggtcag gtagtcgacc atgccggcga cctcctccgc ggtggagtag cggccgagcg
    17161 ggatcttctg ctcgaagcgt gagagcacgt cctcctcggt ggtcgcccag gtcgcggcgt
    17221 acgcctggcg gacccgcacg gccatcggcg tctcgacgta gccggggcag acggcgttga
    17281 ccgtggtacc ggtgtgggcg agctccttgg ccagcgcctt ggtgaagccg atgacgccgg
    17341 ccttggaggc cgagtagggg gcgcccagcg ggacaccctg cttgccgccg gtggaggcga
    17401 cgctgatgat ccgcccgtgc ccggccgcct ccatgccgcc ggtggtgagg acctcgcggg
    17461 tgacgcggaa gacgctggtg aggttggtgt cgatcacgtc ctgccacagc tcgtcggtga
    17521 gggtggaggt gacgccaccg ccgttgcgtc cggcgttgtt gaccagcacg ccgatcgggc
    17581 cgaagcggtc caccgccgcc cggacgaccg tgctcacgtc ctgcgcggag cggacgtcgg
    17641 ccgcgaggcc gtccacctcc aggccctcgc cgcgcaggcg ggcgaccgtc tcggcgacgc
    17701 cctgcgcggt gcgggcgcag atgaagacac tcagcccgcg ccgggccagc cgctcggcgc
    17761 tggccagtcc gatgccgctg gtcgccccgg tcaccagggc gacgtcgccg gtcgtcacgg
    17821 tgctcatcgc atcgatctcc tgtctcgctc acgggtcgcg ggcccgggcg ggcccgccgg
    17881 tcggggcccg cccccgcgcc ccgtcgggaa cccgggggga caggccccgg gccgaccctg
    17941 cccggacggc ttcgactgcg gttcgagcgc gcctcacacg ccgaccgctc caacgggatt
    18001 cgaagcgcgg gtgggagcgt cggcgctgcc caaccaccga cgcaacgagg aggcccggag
    18061 catgaccggt tcgctctacg aggaggtcca gcacttctac gggcggcaga tgcgccacct
    18121 ggacgagggt gaggtcaccg agtgggccgc gaccttcacc gaggacggcg tgttcgccgc
    18181 caacgcccgc ccgcacccgc aggagggtcg cgcggcgatc gagcagggcg cccgggaggc
    18241 cgcccagcgc ctggccgatg ccggaatccg gcaccggcac tggctgggga tgctggaggt
    18301 cgccgcgcag ccggacggcc tggtgctcgc caagacctac gcgctgatcg tcgcgacgcc
    18361 caagggcggg ccggccgccg tgcacctgag ctgcagctgt gaggaccagc tggtgcgcgt
    18421 cgacggcgag ttgaaggtcc ggcaccgcca ggtgcaccgg gacgacctgc ccgcctgaga
    18481 ggaggccacc gtggacctcc cacgggacag tacgaccttc ggtccgccgc tggacgtggt
    18541 ggcggagctg atcggcgggc cccggatcga cgacctcgtc cgccgtgcgg ccgagctgac
    18601 gcctcgtcat attgctttgg tgcacggtga cctggtgctc gaccacgccg cgctggaggc
    18661 ccgggtgagc gactgcgccg aggcgctgcg cgccgcgttc ggcggtcccg gcacggtcat
    18721 cgcgatcgcc gccgagctga ccgtcgactt cgccgtcacc ttcctgggca tctcccgctc
    18781 cgggaacacc agcgccatgt tcaacccgct cgtcccggac gacaccctgg tgcacgtcct
    18841 gaactcctgc ggcgcccggg cggccgtgct gtcgccccgg atgcaccgcc gtgtccaggc
    18901 cctgcgggac cggctgccgc tgctgcggca actggtggtg accgccgacg cgctcgacgg
    18961 cacgcccgtc ctggacgccc tggagcgcac cgccgtcccg gccggcgagg tggtggagac
    19021 cgcctgcctg cagttcacca gcggcaccac cggcgtgccg aagaccgtcc ggctcagcca
    19081 ccgcaacctg ctggtgaacg cggcgcagtc ggcgcacgcc caccggctga cggccgacgc
    19141 cgtctcgctc aacaacctgc cctccttcca cctgatgcac ctgaacgccg cgctcgcggt
    19201 cggcgcgacg cacgtgctct gcccggagga ggaccgcgcg gcgctggtgg gactggcccg
    19261 tacctggcgg gcctcgcacc tgtacagcct gccggtgcgg ttgtcccggc tcgccgggga
    19321 cgagcggctg cccgacttcc gcatcccctc gctacgggcg gtgctgtccg gtggatcggc
    19381 gctgccgccc cggacgacga ccgtcctgca ggagcacttc ggggtgccgg tcgtccaggg
    19441 ctacggcctc gccgagacgt ccccgtcgac gcacttcgac ctgcccgagg ggcccaccct
    19501 cggctccagt gggcccccgg tcgccgggac ggcctgccgg atcgtggacg tccgcaccgg
    19561 cgcggtgctg ccggtgggcg agcgcggtga gatccaggtc cggggcccgc agctgatgct
    19621 gggctacctg ggcgacgggc ccaccgacgc cgtcgacgcg gacggctggt tccgcaccgg
    19681 tgacgtcggc cggatcgacg aggccggccg cctgttcgtc gtcgaccgga tcaaggacgt
    19741 cttcaagtgc gacaactggc tggtgtcgcc gaccgagatc gagcgggtgc tgatgcggca
    19801 cccggccgtc gccgactgcg tggtcttcga ccagcccgac gaactgagcg gcgccgtcgc
    19861 cgtcggcctc gtcgtgccgc gcggcgaggg cgtcgacccg gccgccctgg ccgcgttcgc
    19921 gaacgcccgg ctcccctact acgagcacct gaggcagctg cgcctggtgg agggcatccc
    19981 gcgctccgcc acgggcaagg tccagcggcg cgaactccgt gaccggctgt tcggctccct
    20041 ctgacccgca ccaccccacc cgtccgaccc accacaggag gaacaccgtg tacaccttca
    20101 tcaaccgctt caccgtcacc ggggacgtcg ccgagttcga gacgctcgtc ggcgagatca
    20161 gcgagttcat gagcggccgg cccggcttcc gctcgcaccg gctgtaccgc tgcgccacgg
    20221 acgcctcggt gtacgtggag accgccgagt gggacgacgc ggcctcgcac cgggcggcga
    20281 ccggctcgcc ggagttccgc gcccgggtcg gcaaggtgat gagcctggcc aaggccgagc
    20341 cggccccgtt cgacctgctc gcgcagcacg gcgcctgaga gggggagcac catgacggac
    20401 aacggcgaga tcattgcgca gccggtgatc cagctgcgcg agctggggct ggcggcggcc
    20461 ggcgccgccg ccgtacgggc cgcggcccgg ctgggcctgg ctgacgccct gggcgaggag
    20521 ccggccggcg cggccgagct ggcccgggcc gtgaacgcgg acccggacac cctgcagcgg
    20581 ctgctgcgcg ccctggcctg ctacggcgtg ttcgccgagc agccggacgg tcggtacgtg
    20641 cacaccggcg cctcccggct gctgcgcgag gacaccccgc gcagcctgaa ggacatggtg
    20701 ctctggggca ccgagccgtg gacctgggag ctgtggggcc acctcgacga ggcggtgcgc
    20761 accggcaagg ccgtcttccc cgagctgcac ggcatggact tcttcgacca cctgcacgcc
    20821 cactcccccg agtcggcggc cgtgttcgac cgggcgatga cccagtccag tcggctctcc
    20881 gcgctcgcgc tggccgaccg gctggacctc ggcggggtcg gcacggtggt ggacatcgcc
    20941 ggtggccagg ggcacgtgct ggccaccctg ctggagcgca accccggtct gcgcggcacc
    21001 ctgctggacc tgcccgaggt cgtctccggg gccgacgccc ggctgcaacc gggcggtgcg
    21061 ctggccgggc gcgccacgct gctcggcggc gactgccggc gggagatccc ggtgcaggcc
    21121 gacgtctacc tgctgaagaa catcctggag tgggacgacg agagcaccgt cctgacgctg
    21181 cgcaacgtcg tccgggcggc tgctccgggc agccgggtga tcgtggtcga gaacctggtg
    21241 gacggcagcc ccgagctgcg gttcaccacg gcgatggacc tcctgctgct gctcaacgtc
    21301 ggcggccgca agcacaccag ggccggcctg gtctcgctga tcgaggaggc gggcctgacc
    21361 cgggccgagg tccgtccggt caactcctac ctgcacctgg tggagagcgt ggtgcccgaa
    21421 cggggctgac ccgcccgccc acggccgccg cccccggacc cgtccggggg cggcggccgt
    21481 gctgtccggg ggcggcggcc ctcgcactgt ccggggcggc ggtgagcccc gtcggcacgg
    21541 ccgacggggc tcgggggcgc aacgggaagg ggagcggggt cagatgccct cggcgagccg
    21601 cttcaccgcc tgctcgaccc gctcgtcggt ctcggtgacg gccacccgca cgtgccgggc
    21661 ggccgcggcg ccgtagaact caccgggcgc caccaggatg ccgcggtcgg ccagcgcacc
    21721 gacggtggtc cagcacggct cgtccctggt cgcccagagg aacagcgcac cggccgagtg
    21781 ctcgatccgg aagccggcgt ccaccagcgc cccgcgcagc agctcgcgcc gccgggcgta
    21841 gcgccggcgc tggcccgcca ggtgcgcgtc gtcaccgagc gcggcgacca tggcggcctg
    21901 caccggggcg gggaccatgt ggccggcgtg cttgcgcacc tccagcagcg tcgcgatgac
    21961 ggccgggtcg ccggcggcga agcccgcccg gtagccggcc aggttgaagc gcttggacag
    22021 cgagtgcacc gccagtacgc cgtggtggtc gccgccggtg acctcggcgt ggagcaccga
    22081 gcgggtcgag cgctcccaca cgtggtccag gtagcactcg tcgttgacca ccagggtgcc
    22141 gcgctcgcgc gcccactcga cgaccccgcg cagttcggcg gcgtcgagca cccggccctc
    22201 cgggttggac ggggagttca gccacagcag gcgcggcgcg gggccgtcgt agctcagcgg
    22261 gtcgtccgtc cggacgaagg tggcaccggc cagccgagcg ctcacctcgt aggtggggaa
    22321 ggacagttgg ggggcgagga cgacgtcccc cgggcccagg cccagcatgg tgggcagcca
    22381 ggcgatcagc tccttggtgc cgaccgccgg gatcacggcc tccggctcga cgctcacgcc
    22441 ctcgcggcgc agcagccagg ccgcggcggc ggcccgcagc gcgggcgtgc cctcggtgga
    22501 cgggtagccc ggggcgtcgg ccgcggcggc cagggccgcg cgcacggcct ccggggtcgg
    22561 gtcgaccggg tcaccgagcg ccaggttgac caacccgtcg gggtgggcgg ccgcgcgcct
    22621 gcggtacggg aacagaacgt cccaggggaa cttcggcagc cgctcgatca tgcctgcgcc
    22681 cccgccccga cgttgcgggc cagcggcgga gcctggcagt cggagtcgat gccccaggag
    22741 acgatccgct ccggcgtgat ccggatcagc tcgtcgtcga cgtgcggcag gatctccttg
    22801 ccgccggtcg ccagcgcgac ggcggtgccc cggatctcga tcccgcggac gacccagcgc
    22861 tgcgcgtcca cgatgtcgtc caccaccagt gacacccgcg gatgcccctg cacgtggcgg
    22921 tacttgaggc tgcgggccat gccgcgcccg gtcacgtcga cggtgccgag ctcggcgttg
    22981 tagtggaagc ccagcgggac gacgtgcggc tgtccccggc cgtccacggt ggccaggcgg
    23041 gcgagcggct gcgaggccag gtaggcggcc tctttcgcgg tgaatggcat ggctgtcctc
    23101 ggtgtctgcg ggtcagggtc ggcgcccacg ctaggcagcc cgcttcgagc ggccttggtg
    23161 ccgttcggcc tgctcgcgta cccgcgctgg actccggctc gaagtccggc tgacacggtg
    23221 aggccgtcgt accggaccga gacgggaggt cgcgttggac tgcgatgtgg tggtggcggg
    23281 agcggggccg accggcctga tgctcgcctg cgaactggcc ctgggcggag cccgggcggt
    23341 ggtggtggaa cggcgccgcg agccggagaa gcactccaag gccatgggca tgcagggccg
    23401 caccgtggaa ctgctcgaac tgcgcgggct gctcgaccgc ttcaaggagg gcgcgggcgt
    23461 gctgcagggc ggcaacttcg ccagcctggg cgtgccgatg cgcttcgagg agttcgacac
    23521 ccgccacccg tacgtgctgc tggtgcccca actgcgcacc gaggagctgc tcgccgaacg
    23581 ggcccgcgaa ctgggcgtgc ggatcgtgcg cggctcgggt gtcaccggct tcgcccagga
    23641 cgccgacggg gtcaccgtag agacggacac gggcccgctt cgggcacggt acctggtcgg
    23701 ctgcgacggc ggcggcagca ccgtccgcaa ggccgccggc atcagcttca ccggacagga
    23761 cccgcacatg tacgccctca tcggcgacat gcgcttcagc ggcgacctgc cgcgcggcga
    23821 gggcctcggc ccgatgcggc cggtgggcct ggtcaacccc gccaagcggt cctggttcgg
    23881 cgccttccag caccagccgg gcgtctaccg ggccaccgtc gcctggttcg accggccctt
    23941 cgccgaccgc cgcgccccgg tcaccgagga ggagatgcgc gccgcactgg tcgagcacac
    24001 cggcagtgac cacgggatgc acgacgtcac ctggctgtcc cgcctcaccg acgtctcccg
    24061 gctggccgac tgctaccggc agggccgggt gctgctggcc ggcgacgccg cgcacatcca
    24121 cctgccggcc ggcggccagg ggctcaacct gggtttccag gacgccgtca acctcggctg
    24181 gaagctggcc gccgtggtcc gcggccacgg caccgaggag ctgctggaca gctacggccg
    24241 cgagcgtcgc ccgatcgccg acggcgtggt gcgcaacacc cgcacccagg ccgtcctgat
    24301 cgacccggac ccgcggtacg aggcactgcg ccagaccttc cgcgacctca tggcgctgcc
    24361 cgacaccaac cgccacatcg ccggcatgct ctccggcttc gacgtcgcct acggcggcgg
    24421 cgaccaccct ctggtcggcc gccggatgcc ggacgccgag ctgatcaccg cggacgggcc
    24481 gcggaggatc agcgattgct tcgccggggc ccgcggtctg ctgctgctcc ccgaacaggc
    24541 cccgaccgcc tcgccgctgg ccgcctgggc ggaccgcgtg gacaccctga ccgtcaagtc
    24601 gggcggcccg gacgcggaca ccgcccacct cgtccgcccg gacggctacg tggcctgggc
    24661 cggcgaaccg gcccgcaccg aggaactgca ccacgccgcg accacctggt tcggcgcggc
    24721 ggcctgatcc ccctccccct gagaaaggac gcacgatgac ctcgtccacc gacagcgccg
    24781 ccgcccgcgc gcgccggatc gtcgccctca acaccgccta cttccaggcg aaggcgctgc
    24841 agagcgcggt cgagctcggc ctcttcgagc tgctcgccga gcgccccgcc gggctcgacc
    24901 ggatccgcgc cgaactgggc gtccagcacc ggctgttcaa ggacttcctg aacgccctgg
    24961 tcggcctcgg cctgctggac gagcaggacg gcggctaccg ggcctccgag ctcgcccggg
    25021 agttcctgct ccccggcccc acgtacctcg gcggcaccgc ccgccagcac gcccggctgc
    25081 actaccacgc ctgggcgcag ctgaccgacg cgctgcgcga cggcaaggcc aagtcggccg
    25141 tggccgcgca gggccagctg gcctacccca agcagtacga ggacctggac cgcgcccggc
    25201 agatcatgct gcacatggac gcccacaacg gtttcacggc cgacgagttg gcgcgcgcga
    25261 tcgactggag ccggtacacc tccttcgtgg acgtcggcgg cgggcgcggc aacgtcgcct
    25321 cccggatcgt caccgcccac ccgcacctgc gcggcggggt cttcgacctg ccggcgctgc
    25381 gcccgctctt cgaggagctg gtggtctcgg ccggaaccgc cgaccgggtg gacttccacg
    25441 gcggtgactt cttcgccacc gacctgccgg aggcggacgt ggtgatcttc ggtcacgtcc
    25501 tgccggactg gccggtcggg gaccgcaggg agctgctgcg ccgcgcccac aaggcggtgc
    25561 gcccgggcgg cctggtggtg ctgtacgacg ccatgatcga cccggaggaa cgcgacccgg
    25621 aggtcctgct gcagcggatc aaccacacca tgatccggga cgaggccggg gcctactcgc
    25681 tgcaggaggc ccgcgcctac ctggaggagg ccggcttcac cgtcgaccgg atcgccgcct
    25741 ccgacaccat cacccgcgac cacttcgcca tcggcgtcaa gtcggtctga aggaaaagga
    25801 gttcgacatg accgacacaa ccgcggatca gacgcggcac ggcgaccggc cgtacgacgt
    25861 cgtcatcatc ggcagcgggc tgtcgggcac catgctcggc tcgatcctcg ccaagcacgg
    25921 cttccggatc atgctgctgg acggtgccca ccacccccgc ttcgccgtcg gcgagtccac
    25981 catcgggcag acgctggtgg tgctgcggct gatctcggac cggtacgggg tgccggagat
    26041 cgccaacctg gcgagcttcc aggacgtcct cgccaacgtc agcagttcgc acgggcagaa
    26101 gagcaacttc ggcttcatgt tccaccggga cggcgaggag ccggacccga acgagaccag
    26161 ccagttccgc atcccctcga tcgtcggcaa cgcggcccac tttttccgcc aggacaccga
    26221 ctcctacatg ttccacgccg cggtgcgcta cggctgcgac gcccggcagt actaccgggt
    26281 ggagaacatc gagttcgacg acggcggggt gaccgtctcc ggcgcggacg gcagcaccgt
    26341 ccgggcccgc tacctggtcg acgccagcgg cttccgctcg ccgctggcaa ggcagttggg
    26401 actgcgggag gagccgagcc ggctcaagca ccacgcccgc tcgatcttca cccacatggt
    26461 cggagtggac gcgatcgacg accacgtgga cacgccggcc gagcttcgcc cgccggtgcc
    26521 gtggaacgac gggacgatgc accacatctt cgagcgcggc tggatgtgga tcatcccgtt
    26581 caacaaccac cccggggcca ccaacccgct gtgcagcgtc ggcatccagc tcgacgagcg
    26641 ccgctacccc gcccggccgg acctgacgcc cgaggaggag ttctggtccc acgtggaccg
    26701 cttcccggcg gtgcagcggc agttgaaggg cgcccgcagc gtgcgcgagt gggtgcgaac
    26761 ggaccgcatg cagtactcct cgagccggac ggtcggcgag cgctggtgcc tgatgtcgca
    26821 cgcggctggc ttcatcgacc cgctcttctc ccgcggcctg tccaacacct gcgagatcat
    26881 caacgcgctg tcctggcggc tgatggccgc gctgcgcgag gacgacttcg cggtcgagcg
    26941 cttcgcctac gtggaggaac tggagcaggg cctgctggac tggaacgaca agctggtcaa
    27001 caactccttc atctccttct cgcactaccc gctgtggaac tcggtcttcc ggatctgggc
    27061 ctcggccagc gtgatcggcg gcaagcgcat cctcaacgca ctgaccagga ccaaggagac
    27121 cggcgacgac agccactgcc aggcgctgga cgacaacccg tacccgggcc tgtggtgtcc
    27181 gctggacttc tacaaggagg ccttcgacga gctcaccgag ctgtgcgagg ccgtggacgc
    27241 cgggcgcacc acggccgagg aggccgcgcg ggtgctggag cagcgggtcc gcgagtcgga
    27301 ctggatgctg ccggccctgg gcttcaacga ccccgacacc caccacatca acccgacggc
    27361 ggacaagatg atccggatcg cggagtgggc caccggtcac caccgcccgg agatccgtga
    27421 gctgctggcc gccagtgccg aggaggtcag ggcggcgatg cgggtcaagc cgtagcgcga
    27481 ggggcaacgg cgagcagcgt ccgcgggacg gctgctcccg gacgcgggcc tcgccgttcg
    27541 ccgcacgcgg gtgggctcag ccctcggccg ccagggtcag ggcggccgtc cgcggatcct
    27601 cctccaccgg ccagcgggcg taggagcggc gccagtacat cagcgggctg ggcacctcgg
    27661 gccgggggcc gccggccacc accgcgccga tcacgatggt gtggtctccc gcgtcgaggg
    27721 ccgcggcgac ccggcactcg gcgtgcgcga cgacgtcggc cgacatgacc ggcacgccac
    27781 cggcgctgcc cggctcccac cggacgtccc ggaagcggtc gtccacgggc gcggcgaagc
    27841 gcgcggacgt ggactcccct ccgccgcgca gcacgttgac ggcgaactcg ccgcgctcca
    27901 ggagggcctt cagcacccgg ctgtcgcggt tgatgcagac cagcaacagg ggcggggcct
    27961 tggagacgct gcaggcggcc gaacaggtca acccgtacgg ctccccgtcc ggtcccaggg
    28021 tcgtcaccac ggtgaccccg gtcggcaggg cgcccatgat cgacaggaag gtgtctccgt
    28081 ccaccaggcc gggggccagg tccagcggca gggacagggg ttcggggggc atcggtcctc
    28141 cactctcggc gggtcggtgc ccccatgctc gcggggcgcc ttcgagccgg cgccgggccg
    28201 tcgtcgggcc ctccgggcac gcgaacgggc gcgcggacgg gcgcgcgcga gggcgcgcgg
    28261 acgcggccgg agccggagcg gaaaagcgcg tacccccggc acgggggtga ccgggggtac
    28321 gcgggttcag ggggtgcggg tgcgcgcgct cactcctcgt cgctcagttc ccgcagcggg
    28381 aaggtgagca ggaagcccac cgcaaggatc aggccgccga ccaggaacat cgtgtcgaag
    28441 cccgaggtga aggcgtcgac cgccgaggcg ctcaggccgc cggtggagtc cgggtcggag
    28501 agcgctcggc gcacggcctc gtccgggtcg gccccgtcga gcctgccggc ggcgacgccg
    28561 aacagcaccg acatgaagac ggcggcgccg ctcgtgccgc cgagctggcg gaacagaccg
    28621 gaggcggcgt tggccacgcc cagctcggac ttgggcgccg agctctggat cgccagggtg
    28681 atgacggtct gggagagccc gatgccgaag cccagccagg ccgcgatcac cacgatcacc
    28741 gcgagcgggg tgtccgcgcc cgcggcggag agcgacagca atgctccggc catcgagccg
    28801 aggcccacga tcgcgggctt cttgtagcgg ttccacttct tgatgatctt ggcgcagatc
    28861 gtctgggaga cgatcgcccc ggtcatcacc gggatgatca ccagtccggc gacggtggca
    28921 ctgcgcccct gcaccagctg caggaacagc ggcagggtgg agaccgtacc gaagatgccg
    28981 acgccgatgg tgaagttgac ggccgtggcc atcgtgatgc caccgcgccg gaacagccgc
    29041 agcgggacca tcgcctccag cccgcgggcc cgctcggcga gcacgaacag caccaggccg
    29101 atcagcgaga cggcgaagag cgtcagcgaa cgcgccgatc cccagcccca gtcgaggccc
    29161 tcctccgcca cgatcagcag cggcaccagg cagagcgcca gggtgagcgc cccccggaag
    29221 tcgatcgggt ggtccaccct gcggtgcggc aggttgagcg ccttgcgcac gctgaccagc
    29281 gccaccagac cgagcggcac gttgatcagg aaggcccagc gccagccggt caccccgagg
    29341 atctcgccgg cgcccgcgaa caggcccccg acgagcgggc cgagcacact ggccgccacc
    29401 caggccatca tcaggtacga gaagtagcgc ccgcgctcgc gcaccggggc gaggtcggcg
    29461 atgacggccg tcggcagcga catcagcccg gcgccgccga agccctggag gacgcgggcg
    29521 atcgccagcg tctccatcga gttcgccatc gcgcaggccg ccgagccgac gatgaagacc
    29581 gcgatcgccg ccaggtagag cggcttgcgg ccgtagatgt cggacagctt gccgtagaac
    29641 ggcatcgcga tcgtggagct gaccagatag ccggtgatca cccaggcctg gacggtctgg
    29701 ccgtgcagtt ggtcgccgat cgtacgcagc gcggtggaga cgatcgtctg gtcgagtgcg
    29761 gcgagcagca cggccaacag gagcccggac agcgcggtga tgatctggcg gtgagtgaag
    29821 ccggcggggc cgccggcgtc gtccgcgacg gcctcgccgg tctgcgaggt ggcgttcgcc
    29881 attttcgttt ctcccaccgg attcgacaag gtcttgtcga attgagcgta gtggctaccg
    29941 tggcggaatg acaagttctt gccgaaatcc cggcccggac gaggctaggc tggccgtgga
    30001 gagcctgcgg ctgcccccat gaccgatctc tcccccgcgg ccgagacctt gagtgacatc
    30061 accacggaac tgttcgccgt caacggagcc ctgctgcgcg cgggcgacgc gctgtccgcc
    30121 cgcttcgggc tcacctccgc gcgctggcag gtcctcgggc tgctggccga ggggccacag
    30181 agcgccgccc acctggcgcg cgagcgcggg ctgcgccgcc aggccgtcca gcagaccgtg
    30241 gtgaagctgg tcgaggaggg cctggtcagc acctccccca acccggccga ccggcgggcc
    30301 ccgctggtct cgctgaccgc caagggcacc gacgccctcg cccggatcga acccgccgaa
    30361 cgcctgtgga tggagcacct cgcgggcggc ctggatccgg acgacctgaa ggccacgctg
    30421 cggctgctgc gtggccttcg ggcggtcctg gccgagggcc tgcccccggc ggcggtcggc
    30481 ggcgcggacg ccgccgacgt cacaggtcca gcgtgacctc gtactcggcg agccaggagt
    30541 tgagccacag caccagctcc agactgcccc ggtcgtaggg ccggctcacc gccccggtcg
    30601 gacgggcagc cgcggccagg gcccgcgcgc ggtccagcag cggcagcacc ggagcgtccg
    30661 gatcggcgag caccccggcc agttcggccc gcagggcgcc ctcgtagccc ggatcctggg
    30721 tcgccgggta cggggtcttc acccgctcga ccaccgagcg cggcagcagg tcggccaccg
    30781 ccgcccgcag caggctcttc tcccggccgt cgaaactctt catctcccag ggcacgttga
    30841 agacgtactc cacgagccgg tggtcgcaga acggcacccg cacctcgagg ccgaccgcca
    30901 tgctcatccg gtccttgcgg tcgagcaggg tctgcacgaa gcgggtcagg ttcaggtggc
    30961 cgatctcgcg catccgcctc tcgggcgccg actcgcccgg cagcaccggc acttcggcga
    31021 gcgcctcggc gtaccgggcc gcccggtagc cgtccaggtc gagcttgtcc agcagacccg
    31081 gctggaacag cgagctgccg ccgaagtagc gcgccgaacc cggggtgagc cacgggaagg
    31141 tggccgcccg cagggccaac gggttgcgga accaccggta gcccccgaag agttcgtccg
    31201 cggcctcgcc ggacagcgcc accgtgacgt tctcccgcac cgcgcggaag aacaggtaga
    31261 gcgagggcca catgtcgccc cagtacgcgg gcggcaggtc ggtggcgcgc agcaccgcgg
    31321 aacgcaccgc cgggtccgac aggccggggc tgtccagcag cacctccagg tggtccgctc
    31381 cgacgtgccc cgccagctcg cgcacgtacg gcgcgtccgc ctcccgccgg acggcgtcgg
    31441 aggcgaaggc gtcggcggcg ccccggaagt ccaccgagaa ggagcgcacc ggcccgctgc
    31501 gggcggccag cgccgtcacg gccgacgagt ccaggccgcc ggagagcagc gtgcccagcg
    31561 ggacgtccga gaccagctga cgggtgacgg tgtcggcgag caggtcacgg acggtgccga
    31621 tggtcgtcgg caggtcgtcg gtgtgctcgc gggcctccag ccgccagtac gtctgccggc
    31681 gcaccccgcc gcgccccacc cggacgagct gacccggacg gacctcgacg agcccggaga
    31741 aaacggccgc ctcgggcgtc ttcaccatgt ccagaacctc gcacagcccg tccgggccga
    31801 cccggcgggg aagggtccgg tccgccagga cggccttggg ctccgagccg aagcgcacgc
    31861 cggcggcggt cggccagtag tagagcggct tgacgcccat ccggtcgcgg gccagcagga
    31921 gttcctcgct gtgctcgtcc cagacggcga aggcgaacat cccgttgagc ctctcgacca
    31981 gcgcggcgcc ccactggagg tagccgcgca ggacgacctc ggtgtcgcag gacgtcctga
    32041 accggtggcc gtgcgaggtg agttcggcgc gcagctcacg gaagttgtag atctcgccgc
    32101 tgaaggtgat cgccgcgccg cggccctcgt gttccgcggt catcggctgc cggccgtgct
    32161 cggggtcgat caccgacagg cgccggtgac cgagcccggc cgcgcggccg aaccaaaggc
    32221 cctcggcgtc cggcccccgg caggccatgg tgtcggtcat cgcctggagc aggtcccggc
    32281 ggtgttcggc cggggcgtcg tagtcgacca cccccacgat tccgcacatg ctcagccggc
    32341 cgtggcgaga ccgaggttga ccgcgtccag gagcatccgc ggcgtggtgg cctccaccac
    32401 ggtctcgtcg ggcagggtga tgccgcgctc gcgctcgatg gtgttgaggg tgttgaacag
    32461 ggcgagcgag tcgtagccga ggtcggcgaa ggggacgtcc aggatgtcgt cgagggcgat
    32521 gccctcgtcg gctccggcag cctccttcag cgcggtgatc aggtcgtcaa gggtgaactc
    32581 tgccatggct gttcctcaca tcggtgggtc ggtccgtcaa atccggaagg tcaggcgggc
    32641 ggtcggccgg cccggtcaac tggtcagtac gagagcgctg ttgaagccgc cgtggccgcg
    32701 ggcgaggacc agcgcgctgc ccagccgggc cggcctcggc cggtcccgca ccaggtcgag
    32761 gtccgggtgg gccggccggc cgatgtgcac ggacggcggg atcaccccgt cccgcaggga
    32821 gagcagcgcg gccgcgacgt ccagcggggc gccgccggcc agcagccggc cggtcatcgt
    32881 cttgggcgcc gtcaccggca ccccgcgcgg gccgaacacc gcgcccagca cctcggcctc
    32941 ggcgcggtcc cgctcggcca cgccgctggc gtcggcgaag accacgtcga cgtcggaggg
    33001 gccgatcccg gcgtcggcga gcgccgtgtc gatcgcccgg cgcagcccgg gcgggcgccc
    33061 ggagccgggt cgggggtcga aggtggccgc gtagccggcg atccgcccgt agtggcggtg
    33121 ctgcccgcgc tcggcggcgc cgtccggggt ctccagcacg agcagtgcgc cgccctcgcc
    33181 cggcaccccg ccggaggcgt cggcgtcgaa gggcaggaag gcccgctgcg ggtcccgccg
    33241 ggggctgacc gtgccgctgc ggctgaggca gagccacgac caggggcaga gcgagccgtc
    33301 caccgcgccg gccagcatca gcgcggtgcc ctcgcgcacg tgccggcggg ccttggccag
    33361 cgcgtccagg ccgcccgcct gctcggccac cagggccgaa ccggggccgc gcatgccgtg
    33421 ccggatcgag atctgcccgg tgttgaccgg gtagaaccac gcgaaggact ggtaggcgct
    33481 gacgtaggcc gggcccttgc tccacagcgc ctggagttcc ttctggccga actcgaagcc
    33541 gccggccgag gcggccgtca cgacgccggc ggagaagtcc ggcatcgtcg tcgggtccgc
    33601 ccccgcgtcg gcgagcgcct cctcggccgc gaccagggcc agccgcgtca tgtggtcggt
    33661 ctgcggcagc agtcggcccg gcaggtgttc ctccggcgtg aagttcacct cgccggccac
    33721 gtgcgcccgg tacccggtgg agtcgaagcg ggtcagcggc ccgagaccgg accggcccgc
    33781 cagcgtggcg tcccagtact ccgcaacgcc ccagccgttc ggtgccacca cgccgatccc
    33841 ggtcaccacg acgtcggtca tccccggctc cactccggct cggcgagcac gatcgcgctc
    33901 tggaagccgc cgaagccgct cgccacgctg agcaccgtgc gcacccgctg ttcccgcgcc
    33961 accagcggca cgtagtcgag gtcgcactcg ggatcgggca cgtgcaggtt ggccgtgggc
    34021 ggcaccaccg agtgctcgat cgccagcgcg ctggcggcga actccagggc gcagaccgcg
    34081 cccagcgagt gcccgatcat cgacttgatc gagctgaccg gcacccggta ggcgtggtcg
    34141 cccaggctct tcttgaacgc ggcggtctcg tgccggtcgt tctgcttggt cgccgagccg
    34201 tgcgcgttga cgtagccgat gtcctcgggg ttcatccggc tgcggtcgag cgcgacccgg
    34261 atcgcctcgg ccatctcgtt cccgtcgacc cgcagcccgg tcatgctgta ggagttgcag
    34321 cgcccggcgt agccggtgac ctcggcgtag atgtgcgcgc cgcgccggat cgcgtgctcc
    34381 cgctcctcca gcacgaacat cgccgcgccc tcgccgaggg cgaagccgtt gcgggtcagg
    34441 tcgaaggggc gcgaggcgct ctcgggttcg tcgttgcgcg gggtggtcgc cttgatcgcg
    34501 tcgaagcagg ccaccgtgat cggggagatc gccgcgtccg aggcgccggc cagcatcacg
    34561 tcggccgcgt cgtcgcggat caggtcgcag gcgtgcgcga tcacgtcgat ccccgaggtg
    34621 catccggtcg acaccacgcc caccgggccc tccgcctcga ccagccaggc cagttcggtg
    34681 gccatcgagg acgggacgaa gtagtcgtag aggtacggga cgccgtgcgc gtcgtcgacc
    34741 agccgctcgc ggccctcgtc gctcaccacg gcgaactcgc ggtccagact gatcgtcatc
    34801 ccacaggcgg tgccggccat caccccggtg cggatcgggt cgttgacgcc cgacactccc
    34861 gagtcgtcca gcgcctcgcg cgcggcgacc accgcgaact gcgcggtgcg gtcccattga
    34921 cggatctgac gctgcgtcaa tccagcggcc tgcgggtcga agtcgcactc ggcggcgacc
    34981 ctggaccgga acggcgaggg gtcgaaggtc gagatcgtcc gggtcgcggt ccggccggcc
    35041 gtcagcagct cccagaacgc cttggtgccc acctcgcccg gtgccaccac gccgatcccg
    35101 gtgaccacca cgcgccggcg gccgtcgtca actcccacca ctgctccccc tgtcgatctc
    35161 cccgtgcgtg tccggcgtca tgccctgacc tcctgtccgt gcgccccgtc cgcgggctcg
    35221 ggcgggcggg gacttgagcc ggaacagatc gtcctggcag gcgttcgcgg cggcttcgag
    35281 ccgccgtcca cgcgcctccg gccccccgcc ttcccgccgc ggcgggaagg gccgcacgca
    35341 cgacggcggc ggcgccgcac ccacggcggc gggaagacga cgcgaaccgg cgtcgaaggg
    35401 cgccccctag cgtctggccg catggacatc gacaccgaca tctgcgtggt cggcggcggc
    35461 ccggccgggc tgaccctcgc cctgctgctg gtccgctcgg gcctgcgcgt caccgtgctg
    35521 gaacgcagcc gctccctgga ccgggcctac cgcggcgaga tcctccaacc cggcggccag
    35581 gccttgctgg acgagctggg cgtgctcggc ccggcccggg cgcacggcgc cgtcgagcac
    35641 gaccgcttcc tgctcgagga gcacggacgc gtcctcatcg acggcgacta ccggcgcctg
    35701 cccgggccgt acaactgcct gctgagcctg ccccagcggc acctgctgac cgaactgctc
    35761 gcggcctgcg aacgccacga aggattccgc cagttcgcgg gcaccaaggc caccgccctg
    35821 atcgaggagg gcggcttcgt ccgcggtgtg gtcgcgggcg gcgcgggcgg ctcccccgac
    35881 cgggtggtgc gggcgcgctg cgtcgtcgcc gcggacggcc gcttctccaa ggtccgctcg
    35941 ctcgccggga tcggctaccg tcgccaggag ctgttcagcc aggacgtcct gtggttccgg
    36001 ttgagcgcac cgccgcgcac ggacacccga cgcccgtgcg acgtccgggt cttccgggcc
    36061 ggcggcaatc cggtactcag ctaccgctcg gtgcccgagg cgctccagct cggctggacc
    36121 ctcccgcacg gcggcttccg caagctggcc gaccgcggca tcggccacat cgtcgaccaa
    36181 ctcgtcgacg ccgcaccgga gtacgccgac ctgatccgcc aggagatcac cggcttcggc
    36241 gacgtctccc tgctggacgt cttctccggc agcgccgagc actgggtgcg cgacggcctg
    36301 ctcctgatcg gcgatgccgc ccacacccac agcccgatcg gcgcccaggg gatcaacctg
    36361 gccgtccgcg acgccgtcgc ggcccacccg gtgctggtcg aggccgtccg cggcggcgac
    36421 gccggcgcgg cccggctcgc cccgtacgaa cggcaacgcc gccccgaagt ggaacggatc
    36481 acccggatcc agcaggtcca gagccgcatg atgctctcca ccgggcgcat ctcctccacg
    36541 gtgcgccccc gggccgcggc gctggtgtcc aggaccccgc tgtacggggc catgctgcgc
    36601 cggatcgcct tcggcaccgc gcccgtccgg ctgcgcgccg atctgctcgc cggggcgggg
    36661 cggtgagcgg cggggcagcg atcgccgccg gcgactcggc gacggcgagc ggggtgctcc
    36721 tcgccctcgc cgtcgtcctc gccagcgcgt tcgtctgcgg ccggatcgcc gcccgggtgc
    36781 gccagcccgt cgtcatgggg gagatcgtcg gcggggtggc cctcggcccc agcctgctcg
    36841 ggctgctgcc ggggcacctg gacgcctcac tgttcccggc ggaggtccag tcctacctgc
    36901 gggtgctgtc ccaactgggc ctggtgctct tcatgttcac cgtcggcctg cgcttcgacg
    36961 tcggccacct gcgcggcgcc gggcgccggg tgacagcggt gtcgctcagc tcggtggccc
    37021 tgccgttcgc gctcggcgtg gggctcgcgg tgctgctcta cccctggttc gacaaggccc
    37081 agttgagcac cgacgggagg ctcggcccgg ccctgttcct gggcgcggcg atgtccatca
    37141 cggcctttcc cgtcctcgcc cggatcatcg ccgagcgacg gatgcagcac gacccgctcg
    37201 gcagcctgtc attggcctgc gcggccttcc aggacttcct cgcctggtgc gcgctggcgg
    37261 tggtggtggc ggtggtggag gccaagggcc tctggtcgct gggacggctg gcgctcgaca
    37321 cggcggtggt ggtcctggtg ctggtcggcg tcgtccgccc gctcctgtcc cggctgctcg
    37381 cccccggccg gcgccgtccc ctcccccggc cgtggatcca cgcggtgctc gtcaccggca
    37441 ccctggtcac cgcctgggtc acggccgaga tcggcctgga cgcggtgttc ggggcgttca
    37501 tgttcggtgc ggcggtgccc cgggaccgga tcgaggcgat cgcgcccgac gtcccggagc
    37561 agatcgagcg ggcgggtctc ctgctgctgc cggccttctt cgcggtgacc ggcctcgccg
    37621 tcgacctcac cggcctcggg ctgcgcggcc tggccgtcgt ggcggcggtg ctggtggcgg
    37681 cctgcgccgg caagttcgtc ggtgcggtcg ccgccgcccg ggccaccggc tcgagccggc
    37741 gcgaggcgcg ggtgctcggc atcctgctca acgcccgggg cctgaccgag ctggtcatcc
    37801 tcaacgtggg ccaccggctc ggggtgatcg acacccggat gttcacggcc atggtcgtga
    37861 tggccctggt cacgacgctg atgacggggc cgctcctgga gcgccacgcg gcgggctccg
    37921 ccggatccgc cacgctcccg gacccggcgc ccgaggccgc acaggcctcg cgggcgccct
    37981 cctgagggcg ggccggccac gacctccggg gggcgtgccc ctcacggcgg ctccgtccac
    38041 ccggagaccc ggcgcagccg ccgactcagc cgccgctcga ccgggctgag tggaacgtcg
    38101 gggcgcagcc gctccgggtg ccccgacggt ggcccgcccc cggcagggcc gcccggctcg
    38161 ccgggccgcc ggaccggccc gggctgcggc ggcggggcca cgtagccggc catctgcccc
    38221 agcgccgcca gtccgcgcag gagcacggcc agcagatcga ggagccgttc gttcggttcg
    38281 cacatccgcc gagcatggcg accggtcctg aagcgcggtt cgagcggtac gggaggggcg
    38341 ccgggcacgg cgaaggacag cccggcaccc tcggaaccac tggagcatgg ccacggcgcc
    38401 gtcggagctg cgggtgcccg tcacgctgac gatccgccgc aggagggtcg ggcgtgtccg
    38461 agggttcccg ccggaccggc cccgagcctc actggtaccg gtaggtggcg gccaccgcga
    38521 ggtggtcgct gccgtcccgg ggcagggtgc gggagtccac cggcttcagc ccgcccttgc
    38581 tcatgatctg gtcgatccgc gccatcggga acgccgcggg ccagctgaag ccgaagccgt
    38641 ccccggccgc gccctgggcc gagcgcatct gcgaggtgac cggtgccagg ctgcggtcgt
    38701 tcatggtgcc gttgaggtcg ccgagcagca ggaccttctt caccggctcg gcctggatcg
    38761 cgtcgccgag cgcctgggcg ctgacgtccc gctggtgggc ggtgaagccg ctctcggcct
    38821 tgagccggac ggacggcagg tgcgcgacgt acaccgcgac cgggccctgg ggggtggtga
    38881 cccgggcccg gaaggccctg gtccagccga tcttcaggtc caccggggag acctcgccga
    38941 tcgggtactt cgaccagagc ccgaccgtcc cctccaccgt gtggtgcggg tacgccccgg
    39001 cgagcccggt ctcgtacgac cgcagctggt tgccggccag ttcctggagc gcgacgatct
    39061 gggcgtccga ggcgaccagg ccgcggatgg tgcccggcac gtcggtgttc ccggcctcga
    39121 cgttgtgggt gaccaccgtc cagtcgccgg tgccgccgct cttgtcggac accagcccgc
    39181 cgaacaggtt ggcccacagc acggcgggca ccagcagggc gagcagcgcg gtggcggagc
    39241 ggcgcagcag cgcgggcacc agcagcaccg ggacggccag gccgacccag ggcagaaagg
    39301 tctccagcag gctgccgagg ttgccgacgc tgttcggcat ctcggcgtgg aaggccagca
    39361 gcaccgcggt gagcagggcc agcagggcga tcaccagtcc gcgccgccag gtgttgccgc
    39421 ccctggcgtc cggtccccag tgccgcaggc cgaggaagcc accggtccgg tcggcgggcg
    39481 tgcccgcgtc ctcggggacg gtggtccgct cggtgctgtc cgcctgcgcc atgcgtggct
    39541 cccgtcgctc gtgccgtcgc cggtccggcg gccggtccgt ggtacgggcg cggcgccgga
    39601 ctggtgccgg tttgatcgga tacccggctc agcctatgcc gggacagacg cgcgcttccg
    39661 ggaccgggtt ccggcgtggc ccggtttggt gagccaggcc acgccgggca cgaagcatgc
    39721 gctccgacgc gctatggggg ttcggaggac ccgtttctag cggggggcga cgccgtcgag
    39781 gacggagtcg accagtttgc gggacagctc cgggtcctcc aggtcggagt cctccgacag
    39841 gatgctgcgg tagaggatcg gccccatcag caggtcgccg agcagttcca cgtcgaggtc
    39901 gtcgcggatc acgccctcgg cgacggcccg ccggatcagg tgcagcccga cctcgcggcg
    39961 cggcctgatc acccgctctc ggtaggcggt gtacagctcg ggcagggtct gcatctgccc
    40021 gagcgccgcc ttgagcaccc agcgggtgcg cttggcgagg ccgcggcggc ggatgtagtc
    40081 gaccatcgcg atcaggtcct cgcgggcgcc accgccggtg ggggccggga tcggctcctc
    40141 cagccggctg acgacgtcga ccagcagggc ctccttgttg ggccagcgcc ggtagatggt
    40201 ggccttgccg acgccggcgg cggtggcgat gccctcgatg gtgagttcgg acagcgtgtt
    40261 gccgtccgcc atgaggtcct cgacggcggt gaagatggcc tgctcggcgg cctcgctgcg
    40321 gggccggccg cggcgtaccg ccgcgcaggg ctgcccggtg tcggcgctcg gcgtgtccgt
    40381 cctcatcccg gctgtctctc cctcgctggg tcccgggccc gcgggcgccg tggtgtgtcg
    40441 gtcgatcggg tccacgggcg gggtcgcccc caccccgggc cgaggccctg ccgaccggat
    40501 gcaccggtcg gcagggccat tgtcgctcag tcgactcgca ggtcggtcga tccgcgggtc
    40561 ggacctccgc gcgggtcagg cctccgcggc cgcggcctcc cgggcccggt cctgctgctc
    40621 gggggcaccg gggccgcccg ggccggcggc cggggccgcg gcgcggcgcg gcagcaggaa
    40681 ccacgcgacc agcgcgccga ccagcgagat gccgaccgag agcgcggcca ccacgtgcat
    40741 ggcgtggatg aaggcgtcgt tcgccggggc gatcagcgcc ttgcccgcgc cgttcgggag
    40801 ccggtcggcg atggccaggg tggcctccag cgactcgccc gccttgtcgc gcagcccctc
    40861 gggcaggtgg gtgagggtgt cggtcatccc gtcgcggtag acggtggaga gcaccgcgcc
    40921 gagcaccgcg accccgagcg agccgccgac ctggcggaag gtgttgttga cggccgagcc
    40981 tgcgcccgcc ttctcgcggg gcagcgagcc catgatcgcg acggtgaccg gcggcatgac
    41041 gtgcgccatg cccgtaccca tgaccaggcc gagcacgatc agcacccaga tcggcgtggt
    41101 cgcggtcagc acggtgtagc cgacgaagcc gagcgcgacc aggaccatgc cgccggcggc
    41161 ggtggcggcg acgccgaggc gctcgaccac cagccgggcc cgcggggcga acagcagctg
    41221 ggcgacggcc agcggcagca tcagcagacc ggcctggagc gcgctgtagc cgcgcacgct
    41281 ctggatgtag aagacgccga agaaggagac gcccatcagc gcgaagaaga tcacgccgac
    41341 cacgaccacc gaggcgctga acaccttgtt gcggaaccag gtgacgtcca gggcggggaa
    41401 cgggatgcgg cgctcgtaga ggacgaacgc ggccagcgcg accacgccga gcagggtcgg
    41461 cccccaggcc gcgaacgcag tgaagtcggc cagctcgccg cccttgatga tgccgtagat
    41521 cagcgcga
//
