Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0000209.1:
Cluster 1Polyketide141528

BGC0000209, chlortetracycline biosynthetic gene cluster from Streptomyces aureofaciens. Locus 1. Partial MIBiG entry.

Chemical compounds

Compound: chlortetracycline
PubChem ID: 54676345
SMILES string: Copy to clipboard
Molecular formula: C22H23ClN2O8
Average molecular mass: 478.882 Da

Class-specific details

Biosynthetic class(es):
Polyketide
Polyketide synthase subclass:
Type II

Gene cluster description

chlortetracycline (BGC0000209). Gene Cluster 1. Biosynthetic class = Polyketide. GenBank HM627755. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous known gene clusters

Literature references

1. Zhu T et al. (2013) Deciphering and engineering of the final step halogenase for improved chlortetracycline biosynthesis in industrial Streptomyces aureofaciens. Metab Eng 19:69-78. doi: 10.1016/j.ymben.2013.06.003. Epub 2013 Jun 22.