LOCUS       BGC0000211             34654 bp    DNA     linear   BCT 11-NOV-2009
DEFINITION  Streptomyces albaduncus chrysomycin biosynthetic gene cluster.
ACCESSION   BGC0000211
VERSION     BGC0000211
KEYWORDS    .
SOURCE      Streptomyces albaduncus
  ORGANISM  Streptomyces albaduncus
            Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
            Streptomyces.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.2.0-924c3663(changed)
            Run date     :: 2022-11-07 17:44:41
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 34654
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     gene            complement(1..450)
                     /gene="chryX"
     CDS             complement(1..450)
                     /codon_start=1
                     /db_xref="InterPro:IPR006311"
                     /db_xref="UniProtKB/TrEMBL:D1H092"
                     /gene="chryX"
                     /product="putative spore-associated protein precursor"
                     /protein_id="CBH32079.1"
                     /transl_table=11
                     /translation="MRFSRSVLAASAVAALAMGATTALAAPASAAPNTTPQKVCGSGYK
                     TVNSVPVGSQGTVYLTYNSTNGKNCVATIRTNPGTARDMSAWIYVPDTDAYDQDYGTYT
                     SYAGPTYVYGKAHCVDWGGSIGNVYVEVYGSNCAALREHRVTYTR"
     source          1..34654
                     /collected_by="Wyeth Pharmaceuticals"
                     /country="USA"
                     /db_xref="taxon:68172"
                     /identified_by="Wyeth Pharmaceuticals"
                     /isolation_source="soil"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces albaduncus"
     protocluster    1..34654
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[7585:10059]"
                     /cutoff="20000"
                     /detection_rule="(t2ks and t2clf)"
                     /neighbourhood="35000"
                     /product="T2PKS"
                     /protocluster_number="1"
                     /t2pks_malonyl_elongations="8|9 (Score: 672.2; E-value:
                     5.2e-205)"
                     /t2pks_molecular_weights="propionyl-CoA_8 (Da): 574.572"
                     /t2pks_molecular_weights="propionyl-CoA_9 (Da): 616.608"
                     /t2pks_product_classes="angucycline"
                     /t2pks_starter_units="propionyl-CoA (Score: 625.0; E-value:
                     0)"
                     /tool="antismash"
     proto_core      7586..10059
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(t2ks and t2clf)"
                     /neighbourhood="35000"
                     /product="T2PKS"
                     /protocluster_number="1"
                     /t2pks_malonyl_elongations="8|9 (Score: 672.2; E-value:
                     5.2e-205)"
                     /t2pks_molecular_weights="propionyl-CoA_8 (Da): 574.572"
                     /t2pks_molecular_weights="propionyl-CoA_9 (Da): 616.608"
                     /t2pks_product_classes="angucycline"
                     /t2pks_starter_units="propionyl-CoA (Score: 625.0; E-value:
                     0)"
     cand_cluster    1..34654
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(t2ks and t2clf)"
                     /kind="single"
                     /product="T2PKS"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..34654
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0000211"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..34654
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T2PKS"
                     /region_number="1"
                     /rules="(t2ks and t2clf)"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            893..1678
                     /gene="chryF"
     CDS             893..1678
                     /NRPS_PKS="Domain: PKS_KR (7-170). E-value: 1.3e-14. Score:
                     46.3. Matches aSDomain: nrpspksdomains_chryF_PKS_KR.1"
                     /codon_start=1
                     /db_xref="GOA:D1H093"
                     /db_xref="InterPro:IPR002198"
                     /db_xref="InterPro:IPR002347"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="InterPro:IPR020904"
                     /db_xref="UniProtKB/TrEMBL:D1H093"
                     /function="putative role in chrysomycin biosynthesis"
                     /gene="chryF"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     265.2; E-value: 8.9e-81)"
                     /gene_functions="biosynthetic-additional (t2pks) KR C9
                     (Score: 458.3; E-value: 1.7e-140)"
                     /gene_kind="biosynthetic-additional"
                     /product="putative polyketide ketoreductase"
                     /protein_id="CBH32080.1"
                     /sec_met_domain="adh_short (E-value: 8.1e-41, bitscore:
                     131.1, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANGAGKTALITGATSGIGLAVAHRLAESGFRVFLCARGADAVKR
                     TAGQLRAAGHEADGVACDVRSAERIRAMVTEAAERYGSIDVLVNNAGTGGGGVTADLTD
                     EAWADVIDTNLNSVFHVTRDVLSMGRMRDKSWGRIVNIASTAGKQGVVLAAPYSASKHG
                     VVGFTKSLGNELAKTGITVNAVCPGYVETPMAERVRSGYARAWETTEEDILQRFEAKIP
                     LGRYSTVTEVAGMVGYLVSDTAASVTSQAINVCGGLGNF"
     aSDomain        914..1402
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_chryF_PKS_KR.1"
                     /evalue="1.30E-14"
                     /label="chryF_PKS_KR.1"
                     /locus_tag="chryF"
                     /protein_end="170"
                     /protein_start="7"
                     /score="46.3"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="TALITGATSGIGLAVAHRLAESGFRVFLCARGADAVKRTAGQLRA
                     AGHEADGVACDVRSAERIRAMVTEAAERYGSIDVLVNNAGTGGGGVTADLTDEAWADVI
                     DTNLNSVFHVTRDVLSMGRMRDKSWGRIVNIASTAGKQGVVLAAPYSASKHGVVGFTKS
                     "
     CDS_motif       920..982
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_chryF_0001"
                     /evalue="2.00E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="chryF"
                     /protein_end="30"
                     /protein_start="9"
                     /score="20.4"
                     /tool="antismash"
                     /translation="LITGATSGIGLAVAHRLAESG"
     gene            1821..2153
                     /gene="chryV"
     CDS             1821..2153
                     /codon_start=1
                     /db_xref="UniProtKB/TrEMBL:D1H094"
                     /gene="chryV"
                     /product="hypothetical protein"
                     /protein_id="CBH32081.1"
                     /transl_table=11
                     /translation="MKYTAFLGVRFEPEWFLMDRDEREKFESEHVFPILAKHARFLEIR
                     PFRASAFSSRHTNFFLVHFDDIPAYNSLIEEMRERPLLANRFATITDNFIGIEAAHYTD
                     DEETAA"
     gene            2228..2797
                     /gene="chryH"
     CDS             2228..2797
                     /codon_start=1
                     /db_xref="InterPro:IPR005025"
                     /db_xref="UniProtKB/TrEMBL:D1H095"
                     /function="putative role in chrysomycin biosynthesis"
                     /gene="chryH"
                     /product="putative oxidoreductase/NADH-dependent FMN
                     reductase"
                     /protein_id="CBH32082.1"
                     /transl_table=11
                     /translation="MSTIGIILGSSRPGRQGEAVARWVHGIADERDDAAFEFIDLAEVA
                     LPHFDEAIPPMAGAYAQPHTLAWAERIARLDGFVFVTPEYNNSVPGVLKNAVDFLFAEW
                     GNKAAGFVGYGPTGAIRAVEHLRLIMSELQVATVRAQAALTFATDFADRTTFRPAPESR
                     AVVDQILDQVVSWSQALEPVRRKARA"
     gene            2794..4335
                     /gene="chryOI"
     CDS             2794..4335
                     /codon_start=1
                     /db_xref="GOA:D1H096"
                     /db_xref="InterPro:IPR002938"
                     /db_xref="InterPro:IPR003042"
                     /db_xref="UniProtKB/TrEMBL:D1H096"
                     /function="putative role in chrysomycin biosynthesis"
                     /gene="chryOI"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050:monooxygenase FAD-binding (Score: 534.9; E-value:
                     3.5e-162)"
                     /gene_functions="biosynthetic-additional (t2pks) OXY
                     (Score: 561.3; E-value: 4.5e-171)"
                     /gene_kind="biosynthetic-additional"
                     /product="putative FAD-dependent monooxygenase"
                     /protein_id="CBH32083.1"
                     /transl_table=11
                     /translation="MTGTGTGPGPGAAAPDARLDAPVVVAGAGPTGLMLAGELRLGGVE
                     VIVLDRLTEPVTESRGLGFTARATEVFDQRGLLDRFANPEISPRGHFGGIPMDYDVLPG
                     GHFGVRNVEQTETERVLREWATGLGAGVRPGHEVTGVRQSGERVEVEVSGPRGEEVLRC
                     SYLVGADGGRSTVRRAAGFDFPGHDATCEMFLADVAGVGIRPRFLGERVPGGMVMAARL
                     SDDVDRVIVCERGTAPEERTAPPAFQEIAGAWRRLTGEDISHGEARWTSSFTDAARLVT
                     EYRRGRVFLAGDAAHIHLPASGQGLSVGVQDAVNLGWKLAAVVGGHSDESLLDTYHRER
                     HPVGERVLTNTRAQGLLYLGGSEVEPLRAVLGELLDDPGVARRLAGMVSGLDIRCPVGP
                     GTHPLLGLRMPPCDLLVGADATTSACLLRAGRGVLLQLDDDPGPARTAAPWAGRVDVVQ
                     AVCADERLAGTRAVLLRPDGHIAWAAPDGGDLAEALGTWFGAAGRVRRAVTAAHR"
     gene            4396..4725
                     /gene="chryG"
     CDS             4396..4725
                     /codon_start=1
                     /db_xref="GOA:D1H097"
                     /db_xref="InterPro:IPR006765"
                     /db_xref="InterPro:IPR011008"
                     /db_xref="UniProtKB/TrEMBL:D1H097"
                     /function="putative role in chrysomycin biosynthesis"
                     /gene="chryG"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1225:Polyketide synthesis cyclase (Score: 152.3;
                     E-value: 6.5e-47)"
                     /gene_functions="biosynthetic-additional (t2pks) CYC
                     C4-C17/C2-C19 (Score: 184.8; E-value: 3.6e-57)"
                     /gene_kind="biosynthetic-additional"
                     /product="putative cyclase"
                     /protein_id="CBH32084.1"
                     /transl_table=11
                     /translation="MHSTLIVARMDPNSSGDVSRLFGAFDRTGMPERMGTVRRQLFSYQ
                     GLYFHLQDFASENGGERIAKARSHPLFVGISEDLKAHIDAYDPETWRSPSDAIAQRFYH
                     WEQGA"
     gene            4760..5011
                     /gene="chryC1"
     CDS             4760..5011
                     /NRPS_PKS="Domain: ACP (30-81). E-value: 7e-12. Score:
                     37.4. Matches aSDomain: nrpspksdomains_chryC1_ACP.1"
                     /codon_start=1
                     /db_xref="GOA:D1H098"
                     /db_xref="InterPro:IPR006162"
                     /db_xref="InterPro:IPR006163"
                     /db_xref="InterPro:IPR009081"
                     /db_xref="UniProtKB/TrEMBL:D1H098"
                     /function="putative role in chrysomycin biosynthesis"
                     /gene="chryC1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1129:acyl carrier protein (Score: 101.6; E-value:
                     3.1e-31)"
                     /gene_functions="biosynthetic-additional (t2pks) ACP
                     (Score: 110.1; E-value: 9e-35)"
                     /gene_kind="biosynthetic-additional"
                     /product="putative acyl carrier protein"
                     /protein_id="CBH32085.1"
                     /sec_met_domain="PP-binding (E-value: 7.8e-12, bitscore:
                     36.8, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVAVFTLDDLRRILIGVAGADEDIDLGGDSADTLFTDLGYDSLA
                     LLETAAAVSREYGVTLDDEAVTAVTTPRGFVGLVNDAA"
     aSDomain        4850..5002
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_chryC1_ACP.1"
                     /evalue="7.00E-12"
                     /label="chryC1_ACP.1"
                     /locus_tag="chryC1"
                     /protein_end="81"
                     /protein_start="30"
                     /score="37.4"
                     /tool="antismash"
                     /translation="SADTLFTDLGYDSLALLETAAAVSREYGVTLDDEAVTAVTTPRGF
                     VGLVND"
     gene            5072..6016
                     /gene="chryK"
     CDS             5072..6016
                     /NRPS_PKS="Domain: Polyketide_cyc2 (7-149). E-value:
                     4.8e-16. Score: 51.3. Matches aSDomain:
                     nrpspksdomains_chryK_Polyketide_cyc2.1"
                     /NRPS_PKS="Domain: Polyketide_cyc2 (159-310). E-value:
                     1.2e-11. Score: 37.0. Matches aSDomain:
                     nrpspksdomains_chryK_Polyketide_cyc2.2"
                     /codon_start=1
                     /db_xref="InterPro:IPR019587"
                     /db_xref="UniProtKB/TrEMBL:D1H099"
                     /function="putative role in chrysomycin biosynthesis"
                     /gene="chryK"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1128:cyclase/dehydrase (Score: 434.8; E-value:
                     3.1e-132)"
                     /gene_functions="biosynthetic-additional (t2pks) CYC C7-C12
                     (Score: 474.1; E-value: 3.6e-145)"
                     /gene_kind="biosynthetic-additional"
                     /product="putative bifunctional cyclase/dehydratase"
                     /protein_id="CBH32086.1"
                     /transl_table=11
                     /translation="MSGPKVHEAEHHITVAASAKAVHQLLVEVENWPLLFPPSVHVERL
                     EQDGEHERIRIWATANGAAKTWTSRRRIDAAEGRIEFRQEVSSPPVAAMGGTWTVEADG
                     EERCRVRLLHDYRAVDDDPAALEWIAAAVDRNSRAELDALKTHAEAAADGSSPLFSFED
                     SRRIAGRAQDVFDFVNEADLWPRRLPHVARVRLEDEDGLQLLEMDTHAPDGSVHTTTSV
                     RVCLAPHRIHYKQIQVPALMSLHTGEWRFEEDADGVLATSRHTVAVDESAVKAVLGEDA
                     TLEDARAMVRKALGANSLSTLDRAKAHVEGGGS"
     aSDomain        5093..5518
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_chryK_Polyketide_cyc2.1"
                     /domain_subtype="Polyketide_cyc2"
                     /evalue="4.80E-16"
                     /label="chryK_Polyketide_cyc2.1"
                     /locus_tag="chryK"
                     /protein_end="149"
                     /protein_start="7"
                     /score="51.3"
                     /tool="antismash"
                     /translation="EAEHHITVAASAKAVHQLLVEVENWPLLFPPSVHVERLEQDGEHE
                     RIRIWATANGAAKTWTSRRRIDAAEGRIEFRQEVSSPPVAAMGGTWTVEADGEERCRVR
                     LLHDYRAVDDDPAALEWIAAAVDRNSRAELDALKTHAE"
     aSModule        5093..6001
                     /domains="nrpspksdomains_chryK_Polyketide_cyc2.1"
                     /domains="nrpspksdomains_chryK_Polyketide_cyc2.2"
                     /incomplete
                     /locus_tags="chryK"
                     /tool="antismash"
                     /type="unknown"
     aSDomain        5549..6001
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_chryK_Polyketide_cyc2.2"
                     /domain_subtype="Polyketide_cyc2"
                     /evalue="1.20E-11"
                     /label="chryK_Polyketide_cyc2.2"
                     /locus_tag="chryK"
                     /protein_end="310"
                     /protein_start="159"
                     /score="37.0"
                     /tool="antismash"
                     /translation="SFEDSRRIAGRAQDVFDFVNEADLWPRRLPHVARVRLEDEDGLQL
                     LEMDTHAPDGSVHTTTSVRVCLAPHRIHYKQIQVPALMSLHTGEWRFEEDADGVLATSR
                     HTVAVDESAVKAVLGEDATLEDARAMVRKALGANSLSTLDRAKAHVE"
     gene            6048..7523
                     /gene="chryOIV"
     CDS             6048..7523
                     /codon_start=1
                     /db_xref="GOA:D1H0A0"
                     /db_xref="InterPro:IPR002938"
                     /db_xref="InterPro:IPR003042"
                     /db_xref="UniProtKB/TrEMBL:D1H0A0"
                     /function="putative role in chrysomycin biosynthesis"
                     /gene="chryOIV"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050:monooxygenase FAD-binding (Score: 514.4; E-value:
                     5.9e-156)"
                     /gene_functions="biosynthetic-additional (t2pks) OXY
                     (Score: 528.6; E-value: 3.6e-161)"
                     /gene_kind="biosynthetic-additional"
                     /product="putative FAD-dependent monooxygenase"
                     /protein_id="CBH32087.1"
                     /transl_table=11
                     /translation="MTPPDATEQTRVLVVGAGPVGLLLAGDLRRYGAEVVLVDRLARPM
                     TESRASQLNARTMELLDQRGLVDGLGGPQPESAGHFGGLPFDAAGTASRYAGNWKVPQF
                     RTEAALTRWALAAGVDLRREHELCELRVTDEAVTAVLRTPTGPRTVRAAYVVGCDGAGS
                     TVRALAGFELAGNDAVRELLRADIQGVRVPDHRFERRARGFAASARRPDGVTRVMVHES
                     GRPPARRTGPPPFAEVVRAWRTVTGEDISGAAPVWLDSFDDACTQATRYRRGRVLLAGD
                     AAHVHMPVGGQALNLGLQDAANLGWKLAASLHGWAPPGLLDSYHEERHAVGGRVLDNVR
                     AQGLLLFGGGEADPVRAVFGELLAETGAGDLLARMVSGLDVRYDTGPGRAPLLGARMPD
                     LDLTVDGGPTRVARLLHDGHGVLLDLTGDGAGAARFRAALPAGARQVRVVTARPVREHP
                     DGAVFLLRPDGHVVWTDRVRAPLAGAARRWFGV"
     gene            7586..8854
                     /gene="chryA"
     CDS             7586..8854
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (4-415). E-value:
                     1.1e-54. Score: 177.7. Matches aSDomain:
                     nrpspksdomains_chryA_PKS_KS.1"
                     /codon_start=1
                     /db_xref="GOA:D1H0A1"
                     /db_xref="InterPro:IPR000794"
                     /db_xref="InterPro:IPR014030"
                     /db_xref="InterPro:IPR014031"
                     /db_xref="InterPro:IPR016038"
                     /db_xref="InterPro:IPR016039"
                     /db_xref="InterPro:IPR018201"
                     /db_xref="UniProtKB/TrEMBL:D1H0A1"
                     /function="putative role in chrysomycin biosynthesis"
                     /gene="chryA"
                     /gene_functions="biosynthetic (rule-based-clusters) T2PKS:
                     t2ks"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 496.6; E-value:
                     9.7e-151)"
                     /gene_functions="biosynthetic-additional (t2pks) KS (Score:
                     776.3; E-value: 1.5e-236)"
                     /gene_kind="biosynthetic"
                     /product="putative ketoacyl synthase (KSa)"
                     /protein_id="CBH32088.1"
                     /sec_met_domain="t2ks (E-value: 1.8e-242, bitscore: 795.8,
                     seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRRVVITGIGVLAPGGVGTKNFWSLISEGRTATRTLTRFDPTPY
                     RSRVAAEVDFRPQEHGLRAQEIRRMDRAAQFAVVATREAAADSGLELSELDPCRTGVTI
                     GSAVGATTSLEDEYRVVSDDGAARLVDHAYATPHLYDYLVPSSFAAEVAWSLGAEGPST
                     VVSTGCTSGIDAVAHAVELIREGSADVMITGATEAPLSPITVACFDAIKATTVHNDDPE
                     HASRPYDSTRNGFVLGEGAAGFVLEEYESARRRGATVYAEIVGYATRSNAYHMTGLRPD
                     GAEMADAITAALDEARLDPGDLDYVNAHGSGTKQNDRHETAAFKRSLGEHAYRLPVSSI
                     KSMVGHSLGAIGSIEIAASVLAVKENVVPPTANLHRQDPELDLDYVPLTARDWKTDRVL
                     TVGSGFGGFQSAMVLARPGRSTA"
     aSDomain        7598..8830
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_chryA_PKS_KS.1"
                     /domain_subtype="Iterative-KS"
                     /evalue="1.10E-54"
                     /label="chryA_PKS_KS.1"
                     /locus_tag="chryA"
                     /protein_end="415"
                     /protein_start="4"
                     /score="177.7"
                     /tool="antismash"
                     /translation="VVITGIGVLAPGGVGTKNFWSLISEGRTATRTLTRFDPTPYRSRV
                     AAEVDFRPQEHGLRAQEIRRMDRAAQFAVVATREAAADSGLELSELDPCRTGVTIGSAV
                     GATTSLEDEYRVVSDDGAARLVDHAYATPHLYDYLVPSSFAAEVAWSLGAEGPSTVVST
                     GCTSGIDAVAHAVELIREGSADVMITGATEAPLSPITVACFDAIKATTVHNDDPEHASR
                     PYDSTRNGFVLGEGAAGFVLEEYESARRRGATVYAEIVGYATRSNAYHMTGLRPDGAEM
                     ADAITAALDEARLDPGDLDYVNAHGSGTKQNDRHETAAFKRSLGEHAYRLPVSSIKSMV
                     GHSLGAIGSIEIAASVLAVKENVVPPTANLHRQDPELDLDYVPLTARDWKTDRVLTVGS
                     GFGGFQSAMVLA"
     gene            8851..10059
                     /gene="chryB"
     CDS             8851..10059
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (3-401). E-value:
                     2.8e-29. Score: 94.1. Matches aSDomain:
                     nrpspksdomains_chryB_PKS_KS.1"
                     /codon_start=1
                     /db_xref="GOA:D1H0A2"
                     /db_xref="InterPro:IPR000794"
                     /db_xref="InterPro:IPR014030"
                     /db_xref="InterPro:IPR014031"
                     /db_xref="InterPro:IPR016038"
                     /db_xref="InterPro:IPR016039"
                     /db_xref="UniProtKB/TrEMBL:D1H0A2"
                     /function="putative role in chrysomycin biosynthesis"
                     /gene="chryB"
                     /gene_functions="biosynthetic (rule-based-clusters) T2PKS:
                     t2clf"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093:Beta-ketoacyl synthase (Score: 632; E-value:
                     5.7e-192)"
                     /gene_functions="biosynthetic-additional (t2pks) CLF 8|9
                     (Score: 672.2; E-value: 5.2e-205)"
                     /gene_kind="biosynthetic"
                     /product="putative chain length factor (KSa)"
                     /protein_id="CBH32089.1"
                     /sec_met_domain="t2clf (E-value: 5.4e-195, bitscore: 638.9,
                     seeds: 26, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVVAVTGIGAIAPNGQGTEAYWKSTVEGIGGIAEISRFDASAYP
                     SKLAGEVVFDAPAHLPSRLIPATDHMTRLALAAADWALEDAAVRPADLPDFSTGVITAG
                     SAGGFELGQRELENLWSKGSKYVSVYQSYAWFYAVNSGQISIRHGMRGPSGVVVGDHAG
                     GLDAIAQSRRQIRKGTSLIVSGAVDGSLCPWGWVAQMTDPRMSSAADPREAYLPFDPRA
                     GGYVPGEGGALLVMEDLEHARGRGARIYGEVAGYGATTDPRPGSSREPGLRRALTLALD
                     DAGAAPEDVDVVFADAAAVPELDRVEVEAINRVFGAGRVPVTAPKTMTGRPAAGTAALD
                     VAGALLAIRDGVIPPTVNVTRAPAYDIDLVTGSARRAPVRTAVVLARGHGGFNSAVVVR
                     EAR"
     aSDomain        8860..10053
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_chryB_PKS_KS.1"
                     /domain_subtype="Iterative-KS"
                     /evalue="2.80E-29"
                     /label="chryB_PKS_KS.1"
                     /locus_tag="chryB"
                     /protein_end="401"
                     /protein_start="3"
                     /score="94.1"
                     /tool="antismash"
                     /translation="VAVTGIGAIAPNGQGTEAYWKSTVEGIGGIAEISRFDASAYPSKL
                     AGEVVFDAPAHLPSRLIPATDHMTRLALAAADWALEDAAVRPADLPDFSTGVITAGSAG
                     GFELGQRELENLWSKGSKYVSVYQSYAWFYAVNSGQISIRHGMRGPSGVVVGDHAGGLD
                     AIAQSRRQIRKGTSLIVSGAVDGSLCPWGWVAQMTDPRMSSAADPREAYLPFDPRAGGY
                     VPGEGGALLVMEDLEHARGRGARIYGEVAGYGATTDPRPGSSREPGLRRALTLALDDAG
                     AAPEDVDVVFADAAAVPELDRVEVEAINRVFGAGRVPVTAPKTMTGRPAAGTAALDVAG
                     ALLAIRDGVIPPTVNVTRAPAYDIDLVTGSARRAPVRTAVVLARGHGGFNSAVVVREA"
     CDS_motif       9502..9540
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_chryB_0001"
                     /evalue="6.10E-03"
                     /label="PKSI-KS_m4"
                     /locus_tag="chryB"
                     /protein_end="230"
                     /protein_start="217"
                     /score="10.0"
                     /tool="antismash"
                     /translation="FDPRAGGYVPGEG"
     gene            10120..10383
                     /gene="chryC"
     CDS             10120..10383
                     /NRPS_PKS="Domain: ACP (24-79). E-value: 6.7e-15. Score:
                     47.0. Matches aSDomain: nrpspksdomains_chryC_ACP.1"
                     /codon_start=1
                     /db_xref="GOA:D1H0A3"
                     /db_xref="InterPro:IPR006162"
                     /db_xref="InterPro:IPR006163"
                     /db_xref="InterPro:IPR009081"
                     /db_xref="UniProtKB/TrEMBL:D1H0A3"
                     /function="putative role in chrysomycin biosynthesis"
                     /gene="chryC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1129:acyl carrier protein (Score: 101.6; E-value:
                     3.1e-31)"
                     /gene_functions="biosynthetic-additional (t2pks) ACP
                     (Score: 112.6; E-value: 1.5e-35)"
                     /gene_kind="biosynthetic-additional"
                     /product="putative acyl carrier protein"
                     /protein_id="CBH32090.1"
                     /sec_met_domain="PP-binding (E-value: 3.5e-11, bitscore:
                     34.8, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSEFSIDDLKRILAEGAGGENELTGDIEDVAFEDLGYDSLALLE
                     TGSRIGREYGVEFEDTAFVDVDTPRDLVDVVNAHLPAHAARG"
     aSDomain        10192..10356
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_chryC_ACP.1"
                     /evalue="6.70E-15"
                     /label="chryC_ACP.1"
                     /locus_tag="chryC"
                     /protein_end="79"
                     /protein_start="24"
                     /score="47.0"
                     /tool="antismash"
                     /translation="TGDIEDVAFEDLGYDSLALLETGSRIGREYGVEFEDTAFVDVDTP
                     RDLVDVVNAH"
     gene            10415..11599
                     /gene="chryOIII"
     CDS             10415..11599
                     /codon_start=1
                     /db_xref="GOA:D1H0A4"
                     /db_xref="InterPro:IPR001128"
                     /db_xref="InterPro:IPR002397"
                     /db_xref="InterPro:IPR017972"
                     /db_xref="UniProtKB/TrEMBL:D1H0A4"
                     /function="putative role in chrysomycin biosynthesis"
                     /gene="chryOIII"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007:cytochrome P450 (Score: 277; E-value: 4e-84)"
                     /gene_kind="biosynthetic-additional"
                     /product="putative P450 monooxygenase"
                     /protein_id="CBH32091.1"
                     /sec_met_domain="p450 (E-value: 4.5e-16, bitscore: 49.7,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTSTVPRSDIDPYSDASILSPYEDYRRLRDLGPVVWLESHQVFA
                     VARYREVYDALHDHTTFSSGSGVGLTETLNKAQKGSSFTSDPPYHGYVRGLVARHLKPK
                     ALERFHDYIEGWANRLVDELIEKGTFDAVTDFAQAFPLAVVPDLLGWPVEEGKERLLEW
                     ATAGFNAFGPLNERTMSGFPLLKEMSEFLQRMSVPGNLRPGSWGAELVSDAKEGRIEEY
                     LLPGLLGDFLAPSMDTSVSALSSMLWLFGAHPDQWRLLREDEERIPHAFNEILRIESPL
                     RGFTRLTTRERDLGGAPLAAGSRVLLLYGSANRDERQWDDPERFDIGRPGVAQHIGFGH
                     GIHGCVGQALSRLEGHSLLKALSTRVRSIEIGEPAWRLHNTIRGIASLPVTLRT"
     gene            11628..11816
                     /gene="chryY"
     CDS             11628..11816
                     /codon_start=1
                     /db_xref="UniProtKB/TrEMBL:D1H0A5"
                     /function="putative role in chrysomycin biosynthesis"
                     /gene="chryY"
                     /product="putative ferredoxin"
                     /protein_id="CBH32092.1"
                     /transl_table=11
                     /translation="MRIVVDRRRCEGHGLCEGVAPRLLSADEGRAELLVEGDLPVDQEA
                     AATAAVRVCPIAALRTA"
     gene            11851..12819
                     /gene="chryP"
     CDS             11851..12819
                     /NRPS_PKS="Domain: PKS_AT (6-297). E-value: 9.3e-57. Score:
                     184.5. Matches aSDomain: nrpspksdomains_chryP_PKS_AT.1"
                     /codon_start=1
                     /db_xref="GOA:D1H0A6"
                     /db_xref="InterPro:IPR001227"
                     /db_xref="InterPro:IPR004410"
                     /db_xref="InterPro:IPR014043"
                     /db_xref="InterPro:IPR016035"
                     /db_xref="InterPro:IPR016036"
                     /db_xref="UniProtKB/TrEMBL:D1H0A6"
                     /function="putative role in chrysomycin biosynthesis"
                     /gene="chryP"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PKS_AT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1021:malonyl CoA-acyl carrier protein transacylase
                     (Score: 250.7; E-value: 5.5e-76)"
                     /gene_kind="biosynthetic-additional"
                     /product="putative malonyl-CoA carrier protein
                     transacylase"
                     /protein_id="CBH32093.1"
                     /sec_met_domain="PKS_AT (E-value: 5.9e-57, bitscore: 184.5,
                     seeds: 1682, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTTAFVFPGQGSQRVGMGRALTERRPDLLDSHYRVADEVLGIPL
                     TQLCWRGPAEELRAMPVTQPAVFLTSVVTHEVLGGQGVVPDVVAGHSLGEFAAMVTAGV
                     LDWVDVVHLVRLRGRLMDAVNREIPGSMGAVIDVELGELEGLCARAAADTGEIVEIANH
                     NDHRQIVVAGQTGGVARLLELAERGGAQRVLTLDVGGSAHCSLLSGIEPEFRRAVEALD
                     LRDPVVPVISAVTAAPVRTAAEAADCLSRQFTHRVRWTETVEALTAAGVGRFVEVGPGR
                     TLSKLCGRLAPDAETYRTNDTEHVDRVAEALGTARPARARL"
     CDS_motif       11866..11916
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_chryP_0001"
                     /evalue="1.10E-08"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="chryP"
                     /protein_end="22"
                     /protein_start="5"
                     /score="26.9"
                     /tool="antismash"
                     /translation="FVFPGQGSQRVGMGRAL"
     aSDomain        11869..12741
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_chryP_PKS_AT.1"
                     /evalue="9.30E-57"
                     /label="chryP_PKS_AT.1"
                     /locus_tag="chryP"
                     /protein_end="297"
                     /protein_start="6"
                     /score="184.5"
                     /specificity="consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="VFPGQGSQRVGMGRALTERRPDLLDSHYRVADEVLGIPLTQLCWR
                     GPAEELRAMPVTQPAVFLTSVVTHEVLGGQGVVPDVVAGHSLGEFAAMVTAGVLDWVDV
                     VHLVRLRGRLMDAVNREIPGSMGAVIDVELGELEGLCARAAADTGEIVEIANHNDHRQI
                     VVAGQTGGVARLLELAERGGAQRVLTLDVGGSAHCSLLSGIEPEFRRAVEALDLRDPVV
                     PVISAVTAAPVRTAAEAADCLSRQFTHRVRWTETVEALTAAGVGRFVEVGPGRTLSKLC
                     GRLAPDAETY"
     CDS_motif       12094..12213
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_chryP_0002"
                     /evalue="3.90E-17"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="chryP"
                     /protein_end="121"
                     /protein_start="81"
                     /score="54.3"
                     /tool="antismash"
                     /translation="GVVPDVVAGHSLGEFAAMVTAGVLDWVDVVHLVRLRGRLM"
     gene            12816..13799
                     /gene="chryQ"
     CDS             12816..13799
                     /NRPS_PKS="Domain: PKS_AT (10-297). E-value: 4.7e-63.
                     Score: 205.1. Matches aSDomain:
                     nrpspksdomains_chryQ_PKS_AT.1"
                     /codon_start=1
                     /db_xref="GOA:D1H0A7"
                     /db_xref="InterPro:IPR000794"
                     /db_xref="InterPro:IPR001227"
                     /db_xref="InterPro:IPR014043"
                     /db_xref="InterPro:IPR016035"
                     /db_xref="InterPro:IPR016036"
                     /db_xref="UniProtKB/TrEMBL:D1H0A7"
                     /function="putative role in chrysomycin biosynthesis"
                     /gene="chryQ"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PKS_AT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1021:malonyl CoA-acyl carrier protein transacylase
                     (Score: 253.5; E-value: 8.1e-77)"
                     /gene_functions="biosynthetic-additional (t2pks) AT (Score:
                     399.0; E-value: 3.7e-122)"
                     /gene_functions="biosynthetic-additional (t2pks) AT
                     CBH32094.1_Chrysomycin_propionyl-CoA (Score: 625.0;
                     E-value: 0)"
                     /gene_kind="biosynthetic-additional"
                     /product="putative propionyl-CoA carrier protein
                     transacylase"
                     /protein_id="CBH32094.1"
                     /sec_met_domain="PKS_AT (E-value: 3e-63, bitscore: 205.1,
                     seeds: 1682, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRGRPTALLLPGQGFQHAGMAVEIYRRDRDFADAADAFLAALGP
                     EGDTLRDDWLAGADGDTADRGTRAQPLLFMTGYAVGRTLSRRGVRPDVLIGHSVGELAA
                     AALAGVLDLAAAGRIVAGRCAALEEAPAGGMLAVAGVPERVLDHLRGGPAGEHVVLGAH
                     NGRTQTVLAGPEPHLTVAERLLREAGLVARRVRALEPWHSPAMDRAARRFTEVIGSETL
                     RPPGIPIMSARTGRTVTAAEAVRPAFWAGQIAAPVLFWPALGALLDGRDHLLVDGSPAG
                     GLATLARGHPSVRRGASTVVSLLAPPGRDAWSAWTKGIGQLTAAAV"
     CDS_motif       12843..12893
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_chryQ_0001"
                     /evalue="1.00E-04"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="chryQ"
                     /protein_end="26"
                     /protein_start="9"
                     /score="14.9"
                     /tool="antismash"
                     /translation="LLPGQGFQHAGMAVEIY"
     aSDomain        12846..13706
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_chryQ_PKS_AT.1"
                     /evalue="4.70E-63"
                     /label="chryQ_PKS_AT.1"
                     /locus_tag="chryQ"
                     /protein_end="297"
                     /protein_start="10"
                     /score="205.1"
                     /specificity="consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="LPGQGFQHAGMAVEIYRRDRDFADAADAFLAALGPEGDTLRDDWL
                     AGADGDTADRGTRAQPLLFMTGYAVGRTLSRRGVRPDVLIGHSVGELAAAALAGVLDLA
                     AAGRIVAGRCAALEEAPAGGMLAVAGVPERVLDHLRGGPAGEHVVLGAHNGRTQTVLAG
                     PEPHLTVAERLLREAGLVARRVRALEPWHSPAMDRAARRFTEVIGSETLRPPGIPIMSA
                     RTGRTVTAAEAVRPAFWAGQIAAPVLFWPALGALLDGRDHLLVDGSPAGGLATLARGHP
                     SVRRGA"
     CDS_motif       13077..13184
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_chryQ_0002"
                     /evalue="4.50E-14"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="chryQ"
                     /protein_end="123"
                     /protein_start="87"
                     /score="44.4"
                     /tool="antismash"
                     /translation="GVRPDVLIGHSVGELAAAALAGVLDLAAAGRIVAGR"
     gene            complement(13911..14708)
                     /gene="chryX1"
     CDS             complement(13911..14708)
                     /codon_start=1
                     /db_xref="UniProtKB/TrEMBL:D1H0A8"
                     /function="putative regulator"
                     /gene="chryX1"
                     /product="putative regulator"
                     /protein_id="CBH32095.1"
                     /transl_table=11
                     /translation="MVCITHPHIHPEYRATDCRNDTSGSLCTDCEEHLSGMLQRIPTLY
                     LSCELSLGGANAAEERVTSSNSHQGMPFNAAAAEVRSSIMSVLASWAGLVAAERAVDAP
                     QRHVVGMARFLHENIPWLSAHPAAHDLLDELTTLTRLARRASDSRSIRVIPVGPCVREG
                     CAGKLRAVVKVVPGTRPKPSEIRCSADRTHWWASSEWSALASRMGTLRDHRRTWYSVAD
                     IEVLWKIPSGSIYRLANQYRWRRRKISGRVFYHAEDLHDSLPG"
     gene            complement(15081..15686)
                     /gene="chryX2"
     CDS             complement(15081..15686)
                     /codon_start=1
                     /db_xref="GOA:D1H0A9"
                     /db_xref="InterPro:IPR000792"
                     /db_xref="InterPro:IPR001789"
                     /db_xref="InterPro:IPR011006"
                     /db_xref="InterPro:IPR011991"
                     /db_xref="InterPro:IPR016032"
                     /db_xref="UniProtKB/TrEMBL:D1H0A9"
                     /function="putative regulator"
                     /gene="chryX2"
                     /gene_functions="regulatory (smcogs) SMCOG1016:LuxR family
                     DNA-binding response regulator (Score: 141.2; E-value:
                     4.3e-43)"
                     /gene_kind="regulatory"
                     /product="putative two-component response regulator"
                     /protein_id="CBH32096.1"
                     /transl_table=11
                     /translation="MINVLLAEEREMTRGAFLALLAQESDIKTVADLGRSKDILPAIRL
                     HRPDVAVIDMDMLTPDGLSSIQSLFDELPETRTLILTNHGRPGVVRQALNIGVAGFLHK
                     DSPPEKLVSAIRDLAAGRRVIDADLAMSAWQTPLPPLTDRELEVLRLTATGEAVPAIAT
                     RLHLSPGTVRNYLTTVESKLNARTRVDAVRIATDAGWL"
     gene            complement(15930..16916)
                     /gene="chryE"
     CDS             complement(15930..16916)
                     /NRPS_PKS="Domain: NAD_binding_4 (7-184). E-value: 1.4e-17.
                     Score: 55.5. Matches aSDomain:
                     nrpspksdomains_chryE_NAD_binding_4.1"
                     /codon_start=1
                     /db_xref="GOA:D1H0B0"
                     /db_xref="InterPro:IPR001509"
                     /db_xref="InterPro:IPR005888"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:D1H0B0"
                     /function="putative role in NDP-D-virenose biosynthesis"
                     /gene="chryE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score:
                     338.6; E-value: 6.3e-103)"
                     /gene_kind="biosynthetic-additional"
                     /product="putative TDP-glucose-4,6-dehydratase"
                     /protein_id="CBH32097.1"
                     /sec_met_domain="NAD_binding_4 (E-value: 8.8e-18, bitscore:
                     55.5, seeds: 102, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 1e-18, bitscore:
                     58.6, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="RmlD_sub_bind (E-value: 2.6e-18, bitscore:
                     57.2, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTTHLLVTGGAGFIGSHYVRTLLSPEGPGDISVTVLDALTYAGN
                     PANLDPVRAHPGFTFVRGDICDAPLVRSLARRADQIVHFAAESHVDRSITDPAAFTRTN
                     VMGTQILLDAALRAGTRTFVHISTDEVYGSIDEGSWPEDHPLRPSSPYAASKASSDLLA
                     LSHHHTHGLDVRVTRCSNNYGHHHFPEKAIPLFVTRLLDGRKVPLYGDGRNVRDWLHID
                     DHVRAVELVRTSGRPGEVYNIGGGTELTNRQLTERLLAECGAGWDMVEHVADRPGHDLR
                     YSVDWTKIHTELGYRPRKDFATGLAETVAWYRENRPWWEPLKERAML"
     aSDomain        complement(16365..16895)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_chryE_NAD_binding_4.1"
                     /evalue="1.40E-17"
                     /label="chryE_NAD_binding_4.1"
                     /locus_tag="chryE"
                     /protein_end="184"
                     /protein_start="7"
                     /score="55.5"
                     /tool="antismash"
                     /translation="VTGGAGFIGSHYVRTLLSPEGPGDISVTVLDALTYAGNPANLDPV
                     RAHPGFTFVRGDICDAPLVRSLARRADQIVHFAAESHVDRSITDPAAFTRTNVMGTQIL
                     LDAALRAGTRTFVHISTDEVYGSIDEGSWPEDHPLRPSSPYAASKASSDLLALSHHHTH
                     GLDVRVTRCSNNYG"
     gene            complement(16913..17980)
                     /gene="chryD"
     CDS             complement(16913..17980)
                     /codon_start=1
                     /db_xref="GOA:D1H0B1"
                     /db_xref="InterPro:IPR005835"
                     /db_xref="InterPro:IPR005908"
                     /db_xref="UniProtKB/TrEMBL:D1H0B1"
                     /function="putative role in NDP-D-virenose biosynthesis"
                     /gene="chryD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 327.5; E-value:
                     1.2e-99)"
                     /gene_kind="biosynthetic-additional"
                     /product="putative glucose-1-phosphate
                     thymidylyltransferase"
                     /protein_id="CBH32098.1"
                     /transl_table=11
                     /translation="MKALVLSGGAGTRMRPLTHTTAKQLVPVANKPVLFYGLEAIAQAG
                     ITDVGIIVGETADEIEEAVGDGSKFGLDVTYIPQEAPLGLAHAVLISRSFLGDDEFVMY
                     LGDNFIVGGITELVDNFVSDRPDAQILLTHVPNPTVFGVAELDDAGNVARVEEKSPCPR
                     SDLAIVGVYLFGPAVHEAVRAIKPSGRGELEITHAIQWLIDEGRDVRSTTISGYWKDTG
                     NVVDMLEVNRSVLETLEPRIEGEVDEASQIIGRVRIEEGARVRGSRVVGPAVIGRGTVI
                     SDSYIGAYTSVSEDCRVENSEIEFSIVLRDSSIKGVRRVEASLIGRNVTVTPAPAVPHA
                     HRLLLGDHSEVQISS"
     gene            complement(18160..19872)
                     /gene="chryJ"
     CDS             complement(18160..19872)
                     /codon_start=1
                     /db_xref="UniProtKB/TrEMBL:D1H0B2"
                     /function="putative role in self-defense or export of
                     chrysomycin"
                     /gene="chryJ"
                     /product="putative major facilitator superfamily permease"
                     /protein_id="CBH32099.1"
                     /transl_table=11
                     /translation="MARPGGSFLGCGADRRRHHDRQRHPGPDHRGPLDRFRRGPVDPGV
                     LRDRLRGPPPARRTPRRPVRRPQDLRLRSRRLRRHEPGGRPLPRRRPADPGPRTAGGRR
                     RHDPPDLTGAGERHLHRQGPGSGLRHLGLDHRRRGCRGPAARRLAGRHLLALGLRHQHP
                     PGRPDHGRDARPPVRVPANPGPRRRSRRRPVGGRPRPAGVRPDRGAHLRLADDHRVPRR
                     RRPLVERRPLPRVRLVRRVGGGPVGVLAPSGGAGPQERRAADGRRPLLHPVLPQRQRRD
                     ADGRTRRVRHHRRTAAVAAVHPGLQRVRRRTRARRARGGQLRRQRSEFRHGRHGPAALP
                     GADRSRPGGRRPGDAGPDRRDRHLLVDDRDRPVRLRRRRGLRDGAGHQHRAGGRSPAER
                     RTGVGHPERGPGTGLRAGYRRPDHAVLQHPRHRSERPAHRLRPEGRRGRPVQFGRHGQR
                     GLGDPVALRRQADRRGRGRGQRGDVPRPGDGLLRVRRTAGPGPGDHAVRHPSRGRPHRG
                     GEGRAPRTDHQLTGDPARTAREPALAKGPTSRPGRRVEFPPDPPAGSSRHSET"
     gene            19961..20542
                     /gene="chryX3"
     CDS             19961..20542
                     /codon_start=1
                     /db_xref="GOA:D1H0B3"
                     /db_xref="InterPro:IPR000835"
                     /db_xref="InterPro:IPR011991"
                     /db_xref="UniProtKB/TrEMBL:D1H0B3"
                     /function="putative regulator"
                     /gene="chryX3"
                     /product="putative marR family transcriptional regulator"
                     /protein_id="CBH32100.1"
                     /transl_table=11
                     /translation="MSTRGAAGPPTRIEDGRSMTMERADLGGLEVQRDRLMDGLRAFGA
                     NYAEFTQRFATWLGLHSTDAAALVEILYAEDKGAPLSPARLSERVSLSSGATTALLNRL
                     EAAGHIVRTREHTDRRIVTLRSSPHVKPRAEEFFGPYAGRMVAEMSQYTPEQLQQFEDF
                     IVHLRETMDSLLAHEYKESRPGGSGASDRG"
     gene            20814..21953
                     /gene="chryGT"
     CDS             20814..21953
                     /codon_start=1
                     /db_xref="GOA:D1H0B4"
                     /db_xref="InterPro:IPR002213"
                     /db_xref="InterPro:IPR004276"
                     /db_xref="InterPro:IPR010610"
                     /db_xref="UniProtKB/TrEMBL:D1H0B4"
                     /function="putative role in attachment of NDP-D-virenose to
                     polyketide acceptor substrate"
                     /gene="chryGT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MGT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1062:glycosyltransferase, MGT family (Score: 243.4;
                     E-value: 8e-74)"
                     /gene_functions="biosynthetic-additional (t2pks) GT (Score:
                     380.6; E-value: 2.6e-116)"
                     /gene_kind="biosynthetic-additional"
                     /product="putative C-glycosyltransferase"
                     /protein_id="CBH32101.1"
                     /sec_met_domain="MGT (E-value: 5.2e-88, bitscore: 287.0,
                     seeds: 193, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVLFIAAGTSPAGVFALAPLATAVRNAGHEILVAAFDELTPAVA
                     SVGLPVVAVADGHTTESIKGLDRPGGPIGFPWAPEQELPYVGRWFGRQAAVAMDGLLRL
                     ADVWRPDLVVGGTDAHAAALLGSRLGIPYVRQAWDWLHFDGAERYANDELAPELAQAGL
                     ERLPAPDLFIDICPPSLIPPGAERGRPMRWVPGNRQRKLEPWMYGKGERARVCVTLGSF
                     RTAMPEMFAYLCALVERLTALDAEIVVAADETASRKIRERFPGVRADWVPMEFLVRTCD
                     TIVHAGGLTTLNAMAAGTPQVVVNQFQAFEPSLRLLERQGCSVVLHRDDKSPDNTFDAC
                     ERILSDDGYAHRAGELARELGALPPPATVVGDLEALARR"
     gene            22072..23094
                     /gene="chryMT"
     CDS             22072..23094
                     /codon_start=1
                     /db_xref="GOA:D1H0B5"
                     /db_xref="InterPro:IPR001077"
                     /db_xref="InterPro:IPR011991"
                     /db_xref="InterPro:IPR016461"
                     /db_xref="UniProtKB/TrEMBL:D1H0B5"
                     /function="putative role in chrysomycin biosynthesis"
                     /gene="chryMT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:O-methyltransferase (Score: 348.7; E-value:
                     5.6e-106)"
                     /gene_functions="biosynthetic-additional (t2pks) MET
                     (Score: 296.5; E-value: 5.8e-91)"
                     /gene_kind="biosynthetic-additional"
                     /product="putative O-methyltransferase"
                     /protein_id="CBH32102.1"
                     /transl_table=11
                     /translation="MQTTPPKPPPSAQVLQLATSSWTAAAVSAAAELGVADALADGARP
                     SDEIARSVGAHPPTCYRLLWACAAIGLLEESEGRVFALTEAGDALRGDSPHSMRNFARW
                     VGLAADRNTWAGLADSVRTGDPAFARVHGQDVWEYMRDRADVSTVFDDAMTEASRQLIA
                     PVVDAYDFGGTGTLVDVAGGHGALLAAILAAHPGLRGLLYDRPEVVEGAKQTFQDRGVD
                     DRVEIVAGDFFDSVPEGKDAYLLSNVIHDWDDEPSLTILGNCRRALAEGGRVLLVEAVM
                     PERDASSPTVTLMDLNMLVLCGGKQRTETEFAELLGRAGLRLTRVVRAGLHSVVEAVRA
                     "
     gene            23186..23896
                     /gene="chryOII"
     CDS             23186..23896
                     /codon_start=1
                     /db_xref="GOA:D1H0B6"
                     /db_xref="InterPro:IPR007138"
                     /db_xref="InterPro:IPR011008"
                     /db_xref="UniProtKB/TrEMBL:D1H0B6"
                     /function="putative role in chrysomycin biosynthesis"
                     /gene="chryOII"
                     /product="putative anthrone monooxygenase"
                     /protein_id="CBH32103.1"
                     /transl_table=11
                     /translation="MPFITPDNGSLTVFNLFDTVDRDGQKTLLDTMEGIIKGANYPGWR
                     SSTLHGGLDKPCAANYIQWRSVDDLQERYEGENFRHNTVPYFKELTTTVHLLKTEVIAT
                     HLHPGLERIEISPERDDFTVIVVMGVEPENQATLVDLFAKPDSAMADVPGYRSNSILRG
                     LDGDFVVNYAQWDSREAYETFHGLPEDRRPAHTRAMRAQARPLLTSRSSNTYEVVFARS
                     ASDQPSTEQPAGDR"
     gene            23893..26178
                     /gene="chryRM"
     CDS             23893..26178
                     /codon_start=1
                     /db_xref="GOA:D1H0B7"
                     /db_xref="InterPro:IPR006094"
                     /db_xref="InterPro:IPR012951"
                     /db_xref="InterPro:IPR013216"
                     /db_xref="InterPro:IPR016166"
                     /db_xref="InterPro:IPR016167"
                     /db_xref="InterPro:IPR016168"
                     /db_xref="UniProtKB/TrEMBL:D1H0B7"
                     /function="putative role in chrysomycin biosynthesis"
                     /gene="chryRM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1138:FAD linked oxidase domain protein (Score: 503.7;
                     E-value: 1.2e-152)"
                     /gene_kind="biosynthetic-additional"
                     /product="putative dehydrogenase and domain with unknown
                     function"
                     /protein_id="CBH32104.1"
                     /transl_table=11
                     /translation="MTVRAADDGAVRTAPGPPPLPGPVRVGPDDPRYGELVRGDNHRFT
                     GTPDHVELVRSTEQAEDALRRALAAGQRVAVRSGGHCPEAFVAGPEVEVVIDLSLMSRV
                     SYDPELNAVAIEAGATVGHVYKELYRNWNVTLPAGVCTAVGVGGHISGGGYGPLSRLHG
                     LVADHLHAVEVVHVDRSGRVRTVIATREPDDPHRELWWAHTGAGGGNFGIVTRFWMRSP
                     GASGTDPAGLLPRPPASLLTAMVNWTWEQCELPAFTRIVRNFMGWHVANSAPGSPSAGL
                     FASLWVRHRSGGGLTMFVQADATEPDAAAGLDAFLAAVDEGVGVTPFVHRRELPWLTAS
                     RYMGQGDSGPVMGARIKTKAAYLRDVHTDEQIATLYRWFHREDYFGRESLMMLNGYGGA
                     INAVGPADTASVQRDSVIKAAYSASWGDPEEDETHLTWLRGLYGELYAGTGGVPVPGGP
                     TDGSYINYPDIDLADPDHNRSGVPWHQLYYKDNYATLQAVKAAWDPRDVFHHALSVRLP
                     EDDMTYPTAHIPEHYDFRAIYAGEKDASPVQPWDIGRPQPALVAAHDAGEITGDVLDVG
                     CGLGDNAAFLAGRGHRVTAVDVAEAAVREARRRAEDSGVDVEFAVADATRLTGYDGRFD
                     TVVDSACFHSLSEDERERYLRALRTATRPGGRLHMFCFAQEFEAPFPGPHRHTAASLRE
                     MVGGVWNVLSVEAATFASSLGVEDIAALIESEYPDGDVDPARLDGLPLDEHGKATMPVW
                     HVTAERRD"
     gene            26291..27199
                     /gene="chryU"
     CDS             26291..27199
                     /codon_start=1
                     /db_xref="GOA:D1H0B8"
                     /db_xref="InterPro:IPR005913"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:D1H0B8"
                     /function="putative role in NDP-D-virenose biosynthesis"
                     /gene="chryU"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score:
                     101.2; E-value: 1.2e-30)"
                     /gene_kind="biosynthetic-additional"
                     /product="putative NDP-hexose 4-ketoreductase"
                     /protein_id="CBH32105.1"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 4.9e-10,
                     bitscore: 30.1, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="RmlD_sub_bind (E-value: 4.8e-67, bitscore:
                     217.2, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGRPGRRGLLGSASPTSPPPTPGSPSTGRDGPADITRAAGTERLM
                     RAVRPDVVVNAAVFTGVDPCEADPARAYEVNAVGARHVARACADVGARCVYISTDYVFD
                     GTAPDPYDETAPPRPLLTYGMSKLAGEGETLNASPGHLVVRTAALFGPPPPSHRRRPGF
                     VEQILRRAAAGQRADVTDALVMSPTYTADLARMVVELLAADADGGPYHVTNEGSATWYG
                     LAHAAVSGLGLGALPRQAAPGAGAAGPARPAATPLTSVRLPPRVRRLNRPWRDALAEFL
                     RDHGPDALAAARPGPPLPDAP"
     gene            27217..28452
                     /gene="chryCMT"
     CDS             27217..28452
                     /codon_start=1
                     /db_xref="GOA:D1H0B9"
                     /db_xref="InterPro:IPR013216"
                     /db_xref="InterPro:IPR013630"
                     /db_xref="InterPro:IPR013691"
                     /db_xref="UniProtKB/TrEMBL:D1H0B9"
                     /function="putative role in NDP-D-virenose biosynthesis"
                     /gene="chryCMT"
                     /product="putative C-methyltransferase"
                     /protein_id="CBH32106.1"
                     /transl_table=11
                     /translation="MSDLPNCRICGGALREFLDLGEQPMGNAFVTPGRQDDEAGAFRFR
                     LTVAVCEVCTMVQLTDYVRHDRMFHAAYPYRSSQSSVMSAHFENLARRFLQDELNGTDP
                     FIVELGSNDGIMLRTVAKAGVRHLGVEPCGDVAEVGRANGVRVVSEFFDEDLAARIRAA
                     DGTADVVFAANTFSHIDFLDSILRGVKNLLAPGGVFVFEDPYFGDIVQRASFDQIYDEH
                     IFFFTARSVQDMAARHGLELVDVELLPVHGGELRCTLAHTGARPVSPAVPRLLRQEEEQ
                     GLTETATLTRFADGVRELGETLVTRLRELRDQGKRVVGYGATAKSTTLLNYCGIGPDLV
                     SFVCDSTAEKQGRLTPGTHIPVRSSEAFADPYPDYALLLAWNHKDEILDKESAFREAGG
                     RWIHYVPDVHID"
     gene            28517..29446
                     /gene="chryX4"
     CDS             28517..29446
                     /codon_start=1
                     /db_xref="GOA:D1H0C0"
                     /db_xref="InterPro:IPR002139"
                     /db_xref="InterPro:IPR002173"
                     /db_xref="InterPro:IPR011611"
                     /db_xref="UniProtKB/TrEMBL:D1H0C0"
                     /gene="chryX4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1276:PfkB domain protein (Score: 98.6; E-value:
                     6.9e-30)"
                     /gene_kind="biosynthetic-additional"
                     /product="putative hexokinase"
                     /protein_id="CBH32107.1"
                     /transl_table=11
                     /translation="MRFVVTGSIATDHLMTFPGRIGEQLIAGKLDRISLSLLVDDLEVR
                     DGGVAANIAYGLARLGHRPLLVGAVGTDFHDYGARLAALGVDTSAVRVSTTRHTARFLC
                     TTDTDGGQLATFYAGAMAEASTIDLGDVLRRHGGADLVLIGADDPTAMARHTRACRALG
                     VPFAADPAQQLARLTGPEIRELVEGADHLFTNEYERELLLGKTGWTPQDVLRRTGVWIT
                     TLGDEGSRVERAGEPPVGVPAVPARTVADPTGVGDAFRAGYLASLAAGADVERCARAGS
                     ALATLALSAVGTQTYVPAPAHLHEPPPR"
     gene            complement(29597..30229)
                     /gene="chryL"
     CDS             complement(29597..30229)
                     /codon_start=1
                     /db_xref="GOA:D1H0C1"
                     /db_xref="InterPro:IPR008030"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:D1H0C1"
                     /gene="chryL"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="other (smcogs) SMCOG1199:NmrA family
                     protein (Score: 77.1; E-value: 2.8e-23)"
                     /gene_kind="biosynthetic-additional"
                     /product="putative NAD-dependent epimerase/dehydratase"
                     /protein_id="CBH32108.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 2.2e-07, bitscore:
                     21.4, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLTVFGATGGIGQEIVRQALDAGHHVTAVVRNPAGLTVTGTQLE
                     VFRADLTDPEAVRPAVAGRDAVLSGLGARSRKDAGVATRLTRTVLRAMEAEGTRRLLVV
                     SAAPVGPGAEGDGPLDRALRGIVSAVLKDIYADLREMEAELTRSATDWTAVRPPRLQNK
                     PVSGRYRTVVGGTPPRGRLIGRADVAHAMLAMTDDLGTVKQGVGIAY"
     gene            30344..30958
                     /gene="chryX5"
     CDS             30344..30958
                     /codon_start=1
                     /db_xref="GOA:D1H0C2"
                     /db_xref="InterPro:IPR001647"
                     /db_xref="InterPro:IPR009057"
                     /db_xref="InterPro:IPR015893"
                     /db_xref="UniProtKB/TrEMBL:D1H0C2"
                     /function="putative regulator"
                     /gene="chryX5"
                     /gene_functions="regulatory (smcogs) SMCOG1057:TetR family
                     transcriptional regulator (Score: 80.2; E-value: 4.5e-24)"
                     /gene_kind="regulatory"
                     /product="putative tetR family regulator"
                     /protein_id="CBH32109.1"
                     /transl_table=11
                     /translation="MESPGSTRHRPAEARILDAAYELMRTVGLARTTTKEIARAAGCSE
                     AALYKYFAGKEELFIRVLAERLPRLTPLLRSLAAEPGRGTLEDNLTEIARQAALFYEQS
                     FPIAASLHAETQLKRRHDDAMRRMGSGPHLPIRELDAYLRAEQELGRIGTEADTFAAAS
                     LLMGACAQRAFAYDAAQEGARPPVDDFAARLARTLLAGLAG"
     gene            complement(30996..31403)
                     /gene="chryX6"
     CDS             complement(30996..31403)
                     /codon_start=1
                     /db_xref="GOA:D1H0C3"
                     /db_xref="InterPro:IPR002645"
                     /db_xref="InterPro:IPR003658"
                     /db_xref="UniProtKB/TrEMBL:D1H0C3"
                     /function="putative regulator"
                     /gene="chryX6"
                     /product="putative tetR family transcriptional regulator"
                     /protein_id="CBH32110.1"
                     /transl_table=11
                     /translation="MRTNIIRHENMMASYDMVNGWTVVEIDGDMDGHTSPMIRDALIEL
                     IDEGHRHFILDLNFVPFLDSMGLGMIVAVTKRIRGRDGSLRIVSASSRVLRIFDLSGMR
                     QSYEVYHSREEATRTAPTLGGLVHWPHAVSG"
     gene            complement(31466..31828)
                     /gene="chryX7"
     CDS             complement(31466..31828)
                     /codon_start=1
                     /db_xref="InterPro:IPR007438"
                     /db_xref="UniProtKB/TrEMBL:D1H0C4"
                     /gene="chryX7"
                     /product="hypothetical protein"
                     /protein_id="CBH32111.1"
                     /transl_table=11
                     /translation="MVGQIACRRVYEETSPQEGKRVLVDRVWPRGMRKEDARLDEWLRD
                     VAPSSELRKWYGHEPSRFTEFRRRYLEELRDAGHREAAGHLHDLAEHDGLVLLTATKDV
                     DHSQAAVLAEWLAGKG"
     gene            32381..32989
                     /gene="chryX8"
     CDS             32381..32989
                     /codon_start=1
                     /db_xref="GOA:D1H0C5"
                     /db_xref="InterPro:IPR001647"
                     /db_xref="InterPro:IPR009057"
                     /db_xref="InterPro:IPR011075"
                     /db_xref="InterPro:IPR015893"
                     /db_xref="UniProtKB/TrEMBL:D1H0C5"
                     /function="putative regulator"
                     /gene="chryX8"
                     /gene_functions="regulatory (smcogs) SMCOG1057:TetR family
                     transcriptional regulator (Score: 99.7; E-value: 4.5e-30)"
                     /gene_kind="regulatory"
                     /product="putative tetR family regulator"
                     /protein_id="CBH32112.1"
                     /transl_table=11
                     /translation="MAYRKTPAEISRLEAARERLVVCATSVVAEVGWAQASVTAVADAA
                     GIAAGSVYQHFPSKAALAVEVFRRAAGREVDVLGEVLHGPGGPVGRLARGAQVFARRAL
                     ENRGLAYALLAAPAEPAVGAERLDFRRRYRALFAEVVREGVAAGVLPEQNAEITAAALT
                     GAIGEVLVDPLAAPDEGSIEALLTDLTATALRCAGAPAA"
     gene            33017..34654
                     /gene="chryX9"
     CDS             33017..34654
                     /codon_start=1
                     /db_xref="GOA:D1H0C6"
                     /db_xref="InterPro:IPR006089"
                     /db_xref="InterPro:IPR006090"
                     /db_xref="InterPro:IPR006091"
                     /db_xref="InterPro:IPR009075"
                     /db_xref="InterPro:IPR009100"
                     /db_xref="UniProtKB/TrEMBL:D1H0C6"
                     /gene="chryX9"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006:acyl-CoA dehydrogenase (Score: 288.9; E-value:
                     1e-87)"
                     /gene_kind="biosynthetic-additional"
                     /product="putative acyl-CoA dehydrogenase"
                     /protein_id="CBH32113.1"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 8.6e-22, bitscore:
                     68.5, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 1.1e-29, bitscore:
                     94.8, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTTGLVTHEVTNQPPPLTGHDTADDPVLLEGVHREGAAWHLDDL
                     HRLGRLAGSEEAQGWADQANRHEPELRTHDRYGHRVDEVDFHPAYHSLMDVSVSAGIAG
                     AAWTDERPGAHVARAASFMLATMLEPGHLCPVSMTYAVVPALRHAPDLAKTYEPLLTSR
                     VYDPGLRVPAGKRGLLAGMGMTEKQGGTDVRANTTAATEQADGRWRLRGHKWFTSAPMN
                     DLFLVLAQAPGGLSCFLVPRVLPDGSRNTFRIQRLKDKLGNRSNASSEPEFDDTVAWLV
                     GDEGKGVRTIIDMVTMTRLDCVLGSAAGTRAALAQAAHHARHRSVFGAELIDQPLMRNV
                     LADLALESEAATTLALRLAGAADRAQRGDAGERAFLRLATAVGKYWVCKRQPAAVAEAL
                     ECLGGNGYDEASGMPRLYREAPLNGIWEGSGNVNALDMLRALTREPESLEAYRAEVEPA
                     AGADRRLDAAWRELQGELVLTEDASLRARRVIERAALVLQGSLLVRHAPAPVADAFCAS
                     RLAGDRGLAFGTLAPGTDFAGLLGRLPV"
ORIGIN
        1 tcagcgggtg taggtgaccc ggtgctccct cagcgcggca cagttggagc cgtacacctc
       61 cacgtacacg ttgccgatgc tgccgcccca gtcgacgcag tgggccttgc cgtagacgta
      121 ggtcggtccc gcgtacgacg tgtacgtccc gtagtcctgg tcgtacgcgt cggtgtcggg
      181 gacgtagatc cacgcggaca tgtcccgggc ggtgcccggg ttggtgcgga tggtcgcgac
      241 gcagttcttg ccgttggtcg agttgtacgt caggtagacg gtcccctgcg atccgacggg
      301 caccgagttc acggtcttgt agccgcttcc gcagaccttc tgcggggtgg tgttgggcgc
      361 ggcggaggcc ggcgccgcca gggcggtcgt ggcccccatg gccagggccg ctacggcgga
      421 ggcagccagg acggaacggc tgaatctcat atttccccct tgcaactctt cgaggcggtt
      481 gctcctgccc aatgtgaccc acgactcatc cagaaggttg tgctcggatc gggagacgct
      541 gcgcagctga tggacagtca agtgtgttca ctcgcacggc tgttgtgggc gtgcgtcacc
      601 tcttgacaat ctgagctgcg gtgaagaaca tacatttcag attggcaagc ctgtgcccat
      661 cgggagccgc ctccgtcgcg gccttccccc aggagccgat cttcttctct ccctgacgac
      721 gcgcaaggca gggcccgggt ctcctcccgg gccttctttc gttgcgcccc cacccgacgt
      781 gcgcaccgac cgcccccgcc cggcgcccgg tcgcgccagg cgcccgctcg tccgtacggg
      841 gagagccatc accaccgcgt ccccgaccgg tggtcccacc cgaggaggga cattggcgaa
      901 cggtgccgga aagaccgctc tcatcaccgg agcgaccagt ggcatcggcc tggccgtcgc
      961 acaccggctg gccgagtccg gcttccgcgt cttcctgtgc gcccgtggcg cggacgccgt
     1021 gaagcggacg gccgggcagc tccgggccgc gggccacgaa gcggacggcg tcgcctgcga
     1081 cgtccgctcg gcggagcgga tacgggcgat ggtgaccgag gcggccgagc gctacggcag
     1141 catcgacgtc ctcgtcaaca acgcgggcac cggtggcggc ggcgtcaccg cggacctcac
     1201 cgacgaggcg tgggccgacg tcatcgacac gaacctcaac agcgtcttcc acgtcacgcg
     1261 cgacgtgctc tcgatgggcc ggatgcgcga caagagctgg ggacgcatcg tcaacatcgc
     1321 ctcgaccgcg gggaagcagg gcgtggtcct cgccgccccg tactcggcgt ccaagcacgg
     1381 ggtcgtcgga ttcaccaagt ccctcgggaa cgagctggcg aagaccggca tcaccgtgaa
     1441 cgcggtctgc ccgggatacg tggagacgcc gatggcggag cgtgtgcgca gcggctacgc
     1501 ccgggcgtgg gagacgaccg aggaggacat cctccagcgg ttcgaggcga agatcccgct
     1561 gggccgctac tcgaccgtca ccgaggtggc gggcatggtc ggctacctcg tcagcgacac
     1621 cgccgcctcg gtgacctcgc aggccatcaa cgtgtgcggc ggcctcggca acttctgaca
     1681 ccggccgcct ctccccgcga cggcccggct ctcgcggccg cccggccgga tccggccggg
     1741 cggcccccga cgacgcccgg cccgcggccg cgccacctca ccacccgccg caccgcagcg
     1801 gcgacacaag gaggacttcc gtgaagtaca ccgcgttcct cggcgtccgc ttcgaacccg
     1861 aatggttcct catggaccgg gacgagcggg agaaattcga gtccgaacac gtcttcccga
     1921 tcctcgcgaa gcacgcgcgg ttcctggaga tccggccctt ccgggcctcg gccttcagct
     1981 cccggcacac gaacttcttc ctcgtccact tcgacgacat ccccgcgtac aacagcctca
     2041 tcgaggagat gcgcgaacgt ccgctgctgg ccaaccggtt cgccaccatc acggacaact
     2101 tcatcggcat cgaggccgcc cactacacgg acgacgagga gacggcggcc tgagggcccc
     2161 gagggtgccg ggaacacccc accgctcgct cgacgtccgc accgcccgtc acgacagggg
     2221 agcaagcatg tccaccatcg gaatcatcct gggcagcagc cggccgggaa ggcagggcga
     2281 agcggtcgcc cggtgggtcc acggcatcgc ggacgaacgc gacgacgccg ccttcgagtt
     2341 catcgacctc gccgaggtcg ccctgcccca cttcgacgag gcgattcccc ccatggcggg
     2401 tgcgtacgcg cagccgcaca ccctcgcctg ggcggaacgg atcgcccgcc tcgacggctt
     2461 cgtcttcgtc actcccgagt acaacaactc cgtgcccggc gtgctgaaga acgccgtcga
     2521 cttcctgttc gccgaatggg ggaacaaggc ggcgggcttc gtggggtacg ggccgaccgg
     2581 ggccatccgc gccgtcgagc atctgcgcct gatcatgtcg gagctccagg tcgccaccgt
     2641 gcgcgcccag gcggccctga ccttcgccac ggacttcgcc gaccgcacca cgttccggcc
     2701 cgccccggag agccgggcgg tcgtcgacca gatcctggac caggtcgtct cctggtccca
     2761 ggcgctggag ccggtccgcc gcaaggcgcg ggcatgacgg ggacgggcac cggccccggg
     2821 cccggtgcgg cggcgccgga cgcacggctg gacgcgccgg tcgtcgtggc cggcgcggga
     2881 cccaccggac tgatgctggc cggtgaactc cgcctcggcg gcgtggaggt gatcgtcctc
     2941 gaccggctga ccgagccggt caccgagtcc cgcggactcg gcttcaccgc ccgggccacc
     3001 gaggtcttcg accagcgggg cctgctggac cgcttcgcga accccgagat cagcccacgg
     3061 ggccacttcg gcggcatccc gatggactac gacgtcctgc ccggcgggca cttcggcgta
     3121 cgcaacgtcg aacagaccga gaccgagcgc gtgttgagag agtgggccac cggactcggg
     3181 gccggtgtcc ggcccggcca cgaggtcacc ggcgtacggc agtccgggga gcgggtcgag
     3241 gtcgaggtgt ccggcccccg gggcgaggag gtgctgcgct gctcctacct ggtcggcgcg
     3301 gacggcgggc gcagcaccgt gcggcgggcc gcgggcttcg acttccccgg gcacgacgcg
     3361 acctgcgaga tgttcctggc cgacgtcgcg ggcgtcggca tccgcccgcg gttcctcggt
     3421 gaacgggttc ccggcggcat ggtgatggcc gcccggctga gcgacgacgt ggaccgcgtc
     3481 atcgtctgcg aacgcggtac cgcgcccgag gagcgcaccg cgccgcccgc cttccaggag
     3541 atcgccggtg cgtggcggcg gctcaccggt gaggacataa gccacggcga ggcccgctgg
     3601 accagttcct tcaccgacgc cgcgcggctc gtcaccgagt accgccgcgg acgcgtgttc
     3661 ctggccgggg acgccgccca catccatctg ccggcgagcg gccagggcct cagcgtcggt
     3721 gtgcaggacg cggtgaacct gggctggaag ctcgcggccg tcgtcggcgg ccacagcgac
     3781 gagagcctgc tcgacaccta ccaccgggaa cgccaccccg tgggcgagcg cgtcctgacc
     3841 aacacccggg cccagggcct cctctacctc ggcggcagcg aggtggaacc gctgcgcgcg
     3901 gtgctcggcg aactgctgga cgaccccggg gtggcccgcc gtctggccgg gatggtcagc
     3961 ggcctcgaca tccgctgtcc cgtcggcccc ggcacccacc ccctgctcgg gctgcggatg
     4021 cccccctgcg acctgctcgt cggcgcggac gccaccacct cggcgtgtct gctgcgtgcc
     4081 gggcggggcg tactcctcca gctcgacgac gaccccggcc cggcccggac cgccgcaccg
     4141 tgggcgggcc gcgtcgacgt cgtgcaggcg gtctgcgccg acgaacgact cgccggtaca
     4201 cgtgccgtac tgctgcgccc cgacggccac atcgcctggg cggcgcccga cggaggggac
     4261 ctggccgaag cgctcggcac ctggttcggg gccgccggcc gcgtccggcg ggcggtgacc
     4321 gcggcacacc ggtgaccccg cccgccgtgc ggtcccggcc gacggcacag cacatcccga
     4381 cagaaggaga ccgagatgca cagcaccctg atcgtggccc ggatggaccc gaactcgagc
     4441 ggcgacgtga gccggttgtt cggcgcgttc gaccggaccg gcatgccgga gcgcatgggc
     4501 acggtccgcc ggcagctctt cagctaccag ggcctctact tccaccttca ggacttcgcg
     4561 tccgagaacg gcggggagcg gatcgcaaag gcgcgctccc acccgctctt cgtggggatc
     4621 agtgaggacc tcaaggccca catcgacgcc tacgaccccg agacgtggcg gtcgccctcc
     4681 gacgcgatcg cccagcgctt ctaccactgg gagcagggcg cgtgagcgtc cccggcacgc
     4741 catcacccgg aggaacccca tgaccgttgc cgtgttcacc ctcgacgacc tccgacgcat
     4801 cctgatcggc gtggcgggcg ccgacgagga catcgacctg ggcggcgaca gcgcggacac
     4861 gctgttcacc gacctcggat acgactcgct cgccctgctg gagaccgccg cggccgtctc
     4921 ccgggagtac ggcgtcaccc tcgacgacga ggccgtcacc gccgtcacca caccacgggg
     4981 cttcgtcggc ctggtcaacg acgccgcctg acgggtcctt cgcccgcacc tgaccgcgta
     5041 cacccatgcc ctgaacgagc cgggaggcac gatgtccgga ccgaaggtcc acgaagccga
     5101 gcaccacatc accgtcgccg cgtccgcgaa ggccgtccac cagcttctcg tcgaggtgga
     5161 gaactggccg ctgctgttcc cgccgagcgt gcacgtggaa cgcctcgaac aggacggtga
     5221 gcacgaacgg atacggatct gggccaccgc caacggcgcg gccaagacct ggacgtcccg
     5281 caggcgtatc gacgccgccg aaggccggat cgagttccgg caggaggtgt cgagcccgcc
     5341 ggtcgccgcg atgggcggca cctggaccgt cgaggcggac ggcgaggagc gctgccgggt
     5401 gcggctgctg cacgactacc gtgccgtcga cgacgacccg gccgcactgg agtggatcgc
     5461 cgccgccgtc gaccgcaaca gccgggccga actggacgcg ctgaagaccc acgcggaggc
     5521 ggcggccgac ggttcgagcc cgctgttctc gttcgaggac agccgccgga tcgccggacg
     5581 cgcgcaggac gtcttcgact tcgtcaacga ggcggacctg tggccgcggc ggctgccgca
     5641 cgtcgcccgg gtgcggctgg aggacgagga cggactgcag ctgctggaga tggacaccca
     5701 cgcgcccgac gggtcggtgc acaccaccac gtcggtccgc gtgtgcctcg ccccgcaccg
     5761 catccactac aagcagatcc aggtcccggc cctgatgtcg ctgcacacgg gggagtggcg
     5821 gttcgaggag gacgccgacg gcgtcctggc cacgtcccgg cacaccgtcg ccgtcgacga
     5881 gtccgccgtc aaggcggtcc tcggcgagga cgccaccctt gaggacgccc gggccatggt
     5941 ccgcaaggcc ctcggcgcca acagcctgag caccctcgac cgggccaagg cccacgtcga
     6001 gggcggcggt tcatgaccgc gcgcaccggc tgcccgggga cgggaggatg acgccgccgg
     6061 acgccaccga acagacgcgg gtgctcgtgg tcggtgccgg ccccgtgggg ctgctcctcg
     6121 cgggcgacct gcggcggtac ggagcggagg tcgtcctcgt cgaccggctc gcgcggccga
     6181 tgaccgagtc ccgggcgtcg cagctcaacg cccgcaccat ggaactgctc gaccagcgcg
     6241 gcctggtgga cgggctcggc ggaccccagc cggagagcgc cggccacttc gggggcctgc
     6301 ccttcgacgc ggccggcacg gcgagccgct acgcgggcaa ctggaaggtc ccccagttcc
     6361 gcaccgaggc ggccctgacc cggtgggcgc tcgcggccgg cgtcgacctg cgccgggagc
     6421 acgaactgtg cgaactccgc gtcaccgacg aggcggtgac cgccgtcctg cggaccccga
     6481 cgggcccgcg caccgtgcgc gccgcgtacg tcgtcggctg cgacggcgcc gggagcaccg
     6541 tacgcgccct cgccggcttc gagctcgcgg gcaacgacgc cgtacgggag ctgctgcgcg
     6601 ccgacatcca gggcgtacgg gtgcccgacc accggttcga acgccgtgca cgaggcttcg
     6661 ccgcctccgc gcggcgcccc gacggcgtca cccgcgtgat ggtgcacgag tccggccggc
     6721 ccccggcccg ccgcaccggc cccccgccct tcgccgaggt cgtccgcgcc tggcggacgg
     6781 tcaccggcga ggacatcagc ggcgccgcac cggtctggct cgactccttc gacgacgcct
     6841 gcacacaggc cacccggtac cggcgcggcc gcgtgctgct cgcgggcgac gcggcccacg
     6901 tccacatgcc cgtcggggga caggcgctca acctcggcct gcaggacgcg gccaacctcg
     6961 gctggaaact ggccgcgagc ctgcacggct gggcgccacc gggcctgctc gacagctacc
     7021 acgaggagcg gcacgccgtc ggcggacggg tcctggacaa cgtacgggcg cagggactgc
     7081 tgctgttcgg cggaggtgag gccgacccgg tgcgggcggt gttcggcgaa ctgctggccg
     7141 agaccggcgc cggggacctg ctggcccgca tggtgagcgg cctcgacgtg cgctacgaca
     7201 cgggccccgg ccgggcgccg ctgctgggcg cgcgcatgcc cgacctcgac ctgaccgtcg
     7261 acggcggtcc cacgagggtg gcccggctgc tgcacgacgg gcacggggtc ctgctcgacc
     7321 tcaccgggga cggcgccggc gccgcgcgct tccgcgcggc gctgcccgcg ggggcccgcc
     7381 aggtgcgcgt cgtcaccgcg cgccccgtgc gggagcaccc cgacggagcg gtgttcctgc
     7441 tgcggcccga cggacacgtc gtgtggaccg accgggtgcg ggcccccctg gcaggggcgg
     7501 cgcggcggtg gttcggcgtc tgacgcgcgc acgaccgcca tcggattcct gtcgtttcac
     7561 cggagtatga ctggaaggaa agatcatgag gcggcgagtt gtcatcaccg gcataggagt
     7621 gctggcaccg ggaggtgtcg gcaccaagaa tttctggtcg ctgatcagcg agggacgcac
     7681 ggcgacgcgc accctgacgc gtttcgaccc caccccgtac cgctcacggg tcgcggccga
     7741 ggtcgacttc cgcccgcagg agcacggcct gcgggcccag gagatacgcc ggatggaccg
     7801 cgcggcgcag ttcgcggtgg tcgccacccg cgaggcggcg gccgacagcg gactcgaact
     7861 gtccgaactg gacccctgcc gcaccggcgt gaccatcggc agcgccgtcg gggccaccac
     7921 cagcctggag gacgagtacc gggtggtgag cgacgacggc gcggcccgtc tcgtcgacca
     7981 cgcgtacgcc accccgcatc tgtacgacta cctcgtgccg agctcgttcg ccgccgaggt
     8041 ggcgtggtcg ctcggtgccg aggggccgag caccgtggtg tccaccggct gcacctcggg
     8101 catcgacgcg gtggcgcacg ccgtcgagct gatccgcgag ggcagcgccg acgtgatgat
     8161 cacgggcgcg accgaggccc cgctgtcccc gatcaccgtc gcctgcttcg acgcgatcaa
     8221 ggcgacgacc gtgcacaacg acgaccccga acacgcctcc aggccctacg acagcacccg
     8281 caacggcttc gtcctcggcg agggcgcggc gggattcgta ctggaggagt acgagagcgc
     8341 gaggcggcgt ggcgccaccg tctacgcgga gatcgtcggc tacgccaccc gcagcaacgc
     8401 ctaccacatg accggactgc gcccggacgg cgcggagatg gccgatgcca tcaccgcggc
     8461 gctcgacgag gcccgcctcg acccgggcga cctcgactac gtcaacgccc acgggtccgg
     8521 caccaagcag aacgaccgcc acgagaccgc cgcgttcaag cgcagcctcg gcgagcacgc
     8581 ctaccgcctg ccggtgagct ccatcaagtc gatggtgggc cactcgctcg gggcgatcgg
     8641 gtcgatcgag atcgccgcgt ccgtgctggc cgtcaaggag aacgtcgtgc cgcccaccgc
     8701 caacctgcac cggcaggatc ccgaactcga cctggactac gtgccgttga ccgcgcgcga
     8761 ctggaagacc gaccgggtgc tcaccgtggg cagcgggttc ggcggtttcc agagcgcgat
     8821 ggtgctggca cggcccggaa ggagcaccgc atgacggtcg tcgcggtcac cggcatcggt
     8881 gccatcgcgc ccaacggaca gggcaccgag gcgtactgga agtccaccgt cgaagggatc
     8941 ggcggtatcg ccgagatcag ccggttcgac gcctccgcct acccgtcgaa gctggccggc
     9001 gaggtggtct tcgacgcccc cgcgcacctg cccagcaggc tgatcccggc gaccgaccac
     9061 atgacgcggc tcgccctcgc cgccgcggac tgggcgctcg aggacgcggc ggtacggccc
     9121 gcggacctgc ccgacttcag caccggcgtc atcaccgccg gttccgccgg aggcttcgaa
     9181 ctcggccagc gcgagctgga gaacctgtgg agcaagggct ccaagtacgt cagcgtgtac
     9241 cagtcctacg cctggttcta cgccgtcaac tccggtcaga tctccatccg gcacgggatg
     9301 cgcggaccca gcggcgtggt cgtcggcgac cacgcgggcg gcctcgacgc gatcgcccag
     9361 tcccggcgcc agatccgcaa gggcaccagc ctgatcgtct ccggcgccgt ggacggctcc
     9421 ctgtgcccct ggggctgggt cgcgcagatg acggaccccc ggatgagttc cgccgccgac
     9481 ccacgggagg cgtacctgcc cttcgacccg agggccggcg ggtacgtgcc gggcgagggc
     9541 ggcgcgctgc tcgtgatgga ggacctggag cacgcccgcg ggcgcggagc gcggatctac
     9601 ggcgaggtcg ccggatacgg cgcgaccacc gaccccaggc cgggcagttc acgcgaaccc
     9661 ggtctgcgtc gcgcgctcac gctcgcgctc gacgacgcgg gggccgcccc ggaggacgtc
     9721 gacgtcgtct tcgcggacgc ggccgccgtg cccgaactcg accgcgtcga ggtcgaggcg
     9781 atcaaccgtg tcttcggcgc cggccgggtg ccggtcaccg cgccgaagac gatgacaggc
     9841 aggccggcgg ccgggacggc ggcgctggac gtcgcggggg cgctgctggc gatccgggac
     9901 ggcgtgatcc cgccgaccgt gaacgtcacg cgcgcccccg cctacgacat cgacctggtc
     9961 accgggagcg cgcgccgggc tcccgtgcgg accgcggtcg tactggccag gggccacggc
    10021 ggcttcaact ccgcggtcgt ggtgcgcgag gcgcgatgag cggcgcaccg cgagacatca
    10081 cgacaccgtc ccgaacgacc tcttcgacag ggtggaactg tgagcagtga attcagcatc
    10141 gacgacctca agcgcatcct cgccgaggga gccggcggcg agaacgagct gaccggcgac
    10201 atcgaggacg tcgccttcga ggatctcggc tacgactccc tcgccctcct ggagacgggc
    10261 agcaggatcg gccgcgagta cggggtggag ttcgaggaca cggccttcgt cgacgtcgac
    10321 acgccccgcg acctggtcga cgtcgtcaac gcccacctgc cggcccacgc ggcacgcggc
    10381 tgacccgttc ccgcagctca ccgaggagtc cctcatgacg accagcaccg tcccccgcag
    10441 cgacatcgac ccctacagcg acgcgtcgat cctctccccg tacgaggact accggcggct
    10501 gcgcgacctc ggacccgtgg tgtggctgga gtcccaccag gtcttcgcgg tcgcccggta
    10561 ccgggaggtc tacgacgcgc tgcacgacca cacgacgttc tcgtcgggct ccggcgtggg
    10621 actgaccgag acgctcaaca aggcgcagaa gggcagcagc ttcaccagcg acccgccgta
    10681 ccacggctac gtacgcgggc tggtggcccg gcacctgaag ccgaaggcgc tggagcggtt
    10741 ccacgactac atcgagggct gggcgaaccg gctcgtcgac gaactcatcg agaagggcac
    10801 gttcgacgcg gtcaccgact tcgcccaggc cttcccgctg gcggtcgtcc ccgacctgct
    10861 cggctggccc gtcgaggagg gcaaggagcg gctgctggag tgggcgaccg ccggcttcaa
    10921 cgccttcggc cccctcaacg agcgcaccat gtccggcttc ccgctgctca aggagatgtc
    10981 cgagttcctc cagcggatgt cggtccccgg aaacctgcgg ccgggcagct ggggcgccga
    11041 actcgtcagc gacgccaagg agggcaggat cgaggagtac ctgctgccgg gtctgctcgg
    11101 ggacttcctc gcgccctcga tggacacctc cgtcagcgcg ctgtccagca tgctctggct
    11161 gttcggcgcg catccggacc agtggcggct gctgcgcgag gacgaggagc gcatcccgca
    11221 cgccttcaac gagatcctgc gcatcgagtc cccgctgcgc ggcttcaccc ggctcaccac
    11281 gcgcgagcgc gacctgggcg gcgccccgct ggcggccggc tcgcgcgtgc tgctgctgta
    11341 cggctcggcc aaccgcgacg agcgccagtg ggacgacccc gagcggttcg acatcggccg
    11401 gcccggggtc gcgcagcaca tcggcttcgg ccacggcatc cacggctgcg tcggccaggc
    11461 gctctcccgg ctggaggggc acagcctcct gaaggcgctg tccacgcggg tgcgctcgat
    11521 cgagatcggt gaacccgcct ggcggctgca caacacgatc cggggcatcg cgtccctgcc
    11581 cgtgacgctg cggacctgac cgtgtcccga cggaaggcgg aggcgtcatg aggatcgtcg
    11641 tcgaccgacg gcgctgtgag ggccacggcc tgtgcgaggg cgtggcgccc cggctgctgt
    11701 cggccgacga gggccgcgcc gaactgctcg tggaggggga tctgcccgtg gaccaggagg
    11761 ccgcagcgac ggcggcggta cgggtgtgtc ccatcgcggc gctcaggacc gcctgagcgc
    11821 ccggaccgaa gaatggaggt ggtgccggcg atgagcacga cagccttcgt gttcccgggc
    11881 cagggttccc aacgggtcgg catgggacgc gctctgaccg agcggcggcc ggacctgctc
    11941 gactcccact accgggtcgc ggacgaggtg ctggggatcc ccctgacaca gctgtgctgg
    12001 aggggcccgg ccgaggaact gcgggccatg cccgtcaccc agcccgccgt cttcctgacc
    12061 agcgtcgtca cccatgaggt gctcggcggg cagggggtcg tccccgacgt cgtggccgga
    12121 cacagcctcg gcgagttcgc ggcgatggtc accgcggggg tgctcgactg ggtcgacgtc
    12181 gtgcacctgg tccggctgcg gggccggctg atggacgcgg tcaaccgcga gatcccgggc
    12241 agcatgggcg cggtcatcga tgtcgagttg ggtgaactgg agggcctgtg cgcccgggcc
    12301 gccgccgaca cgggcgagat cgtcgagatc gccaaccaca acgaccaccg gcagatcgtg
    12361 gtcgccgggc agaccggcgg tgtggcgcgc ctcctcgaac tcgccgaacg gggcggggcc
    12421 cagcgggtac tgacgctcga cgtgggcggg tcggcgcact gcagcctcct gtccggcatc
    12481 gagccggagt tccggcgggc ggtcgaggcg ctcgacctgc gcgatccggt cgtccccgtg
    12541 atctcggcgg tgacggcggc ccccgtccgt acggccgccg aggccgccga ctgcctgtcg
    12601 cggcagttca cccaccgggt gcggtggacg gagacggtgg aggcgctgac cgcggcgggc
    12661 gtcggccggt tcgtggaggt ggggcccggc aggacgctga gcaagctctg cggccggctg
    12721 gccccggacg cggagacgta ccggaccaac gacaccgagc acgtcgaccg ggtggccgag
    12781 gccctcggca ccgcgcggcc ggcccgggcg cggctgtgac gcgcggccgc ccgacggccc
    12841 tgctcctgcc cgggcagggc ttccagcacg cgggcatggc ggtggagatc taccgccgcg
    12901 acagggactt cgcggacgcg gccgacgcgt tcctcgcggc gctgggcccc gagggcgaca
    12961 cgttgcggga cgactggctg gccggtgcgg acggcgacac ggcggaccgg ggcacacggg
    13021 cgcagccgct gctcttcatg accgggtacg cggtcggccg caccctgtcg cgcaggggcg
    13081 tgcgtccgga cgtgctgatc ggccacagcg tcggcgagct ggcggccgcc gcgctggccg
    13141 gagtactcga cctggccgcg gccggccgga tcgtcgcggg ccgctgcgcc gcgctggagg
    13201 aggcccccgc cggtggcatg ctggccgtgg cgggggtgcc cgagcgggtc ctggaccacc
    13261 tgcggggagg tccggcaggc gagcatgtgg tgctcggcgc gcacaacggc aggacgcaga
    13321 ccgtcctcgc cgggccggaa ccccatctca ccgtcgccga acggctgttg cgggaggcgg
    13381 gactcgtggc gcgccgcgtg cgggcgctcg aaccgtggca ctcgcccgcc atggaccggg
    13441 ccgcccgccg gttcaccgag gtgatcggct ccgagacgct gcgccctccg gggataccca
    13501 tcatgtcggc ccgcacgggc cgtacggtca ccgcggccga ggcggtgcgg cccgcgttct
    13561 gggccgggca gatcgcggcg cccgtgctgt tctggccggc cctgggcgcg ctgctcgacg
    13621 gccgggacca tctcctggtc gacgggagcc cggccggcgg gctggcgacg ctggcgcgcg
    13681 ggcacccgtc ggtgcggcgg ggcgccagca cggtggtgtc cctgctggcg ccaccggggc
    13741 gggacgcctg gagcgcgtgg acgaagggga tcgggcagct gacggccgcg gccgtctgac
    13801 gggcggaggg cggggttccg gtgagcaccg gacgggcgga gggcggggtt ccggtgagca
    13861 ccggaccccg cccttttctc gcgtccgccg ccgggcgggg cgtctgctgc tcagccgggg
    13921 agcgagtcgt ggaggtcctc ggcgtggtag aagacccggc ccgagatctt gcggcggcgc
    13981 caccggtact ggttggcgag gcggtagatg cttccgctgg ggatcttcca gagcacttcg
    14041 atgtccgcga cgctgtacca ggtgcgccgg tgatcgcgga gcgtccccat gcgcgacgcg
    14101 agggccgacc actcgctgga ggcccaccag tgcgtacggt ccgcgctgca ccggatctcg
    14161 gacggcttcg gccgggtgcc ggggacgacc ttgaccacgg cgcgcagctt gccggcgcag
    14221 ccttcccgta cgcacgggcc gaccgggatg acgcggatgc tgcgggagtc gctcgcgcgc
    14281 cgggcgagcc gcgtcagggt ggtgagttcg tcgagcaggt cgtgggccgc cggatgggcc
    14341 gagagccagg ggatgttctc gtggaggaag cgggccattc ccacgacgtg gcgctgcggg
    14401 gcgtcgaccg cccgctccgc ggcgacgagg ccggcccagg aggccaggac cgacatgatc
    14461 gaggagcgga cctcggcggc cgccgcgttg aacggcatgc cctggtggct gttggagctg
    14521 gtgacccttt cctcggccgc attcgctccg ccaaggctta gttcacagct caggtaaagt
    14581 gtcggaatcc tttgcagcat tcccgagagg tgttcctcgc agtcggtgca cagactgccc
    14641 gacgtgtcgt tccggcaatc ggtcgcacgg tattcagggt ggatgtgagg gtgcgttatg
    14701 cagaccatga agctcttccg tttccccgtc ttcgaggccg gggcgaaccg acctcgtccg
    14761 tgcttcaaat gatatgggga agcaattcca tggtggagtg tctccgtcat gaatgtaata
    14821 atggagagca gatggttgat catgggaaaa tcacgaggtc gcccgtgcgg aattcaagca
    14881 ggccgcacat ccgcgggcat gacgaagccc ccaccgggac ggcttggtcg gagccgcccc
    14941 cgcgggggct ttgtcgttgc gtcttgaatg agtgccgtga cgcgtccccg taggtgatca
    15001 ggtatacgat ccggcgtgtg tcgtggctga aaagagccct ttaccgctcc gccttcgtcg
    15061 tggtgaaagc gggtgcggat tcagagccag ccggcgtccg tggcgatgcg cacggcgtcc
    15121 actcgcgtgc gcgcgttgag tttgctctcc acggtggtca gatagttgcg gacggtgccg
    15181 ggggacaggt ggagtcgtgt ggcgatggcc ggaacagcct cgccggtggc ggtcaggcgg
    15241 agcacctcga gctcgcggtc ggtgagcggg gggagcggcg tctgccaggc ggacatcgcg
    15301 agatccgcgt cgatgacacg tcgtcccgcc gcgagatccc ttatagcgct gacgagtttc
    15361 tccggcggtg agtccttgtg cagaaaaccc gcgacgccga tgttcagcgc ttgacgcacc
    15421 acaccggggc gcccatgatt ggtgagaatg agagtacgtg tttccggcag ctcgtcgaaa
    15481 aggctctgaa tcgatgacag gccgtccggg gtcagcatat ccatgtcgat gactgccacg
    15541 tccggccggt gcagtctgat cgcgggcaga atgtccttgc tccgacccag gtcggcgacg
    15601 gtcttgatgt cgctctcctg cgcgagtagg gcgagaaatg cccctcgtgt catttccctc
    15661 tcttcggcga gcaagacgtt aatcactttt cccccaagag gtgatcgcga gcactcggcg
    15721 tcctgcgtcc gccatccgcg cccggtcagg tcgctcaaaa gtctagctac tggtcgctag
    15781 ttttcaagtg cgatcttttc cggtccaaag cgcacatgcg cacatgcgga tctgtgcgag
    15841 acccacacat tcggatggaa tgccctatgc gatgcggggg taagccggcg ggtgcgcggg
    15901 ggagacgcgg cgccgggccc cgggggatgt cacagcatgg cgcgctcctt caggggttcc
    15961 caccacgggc ggttctcgcg gtaccaggcc acggtctcgg cgagccccgt ggcgaagtcc
    16021 ttgcgcggcc ggtagcccag ctcggtgtgg atcttggtcc agtcgaccga gtagcgcagg
    16081 tcgtgccccg ggcggtcggc cacgtgctcg accatgtccc agccggctcc gcactccgcg
    16141 agcagccgct cggtgagctg ccggttggtc agctcggtgc cgccgccgat gttgtagacc
    16201 tcgccgggtc ttccgctcgt gcgcaccagc tcgacggccc gcacgtggtc gtcgatgtgc
    16261 agccagtccc ggacgttgcg cccgtcgccg tacaggggca ccttccttcc gtcgaggaga
    16321 cgggtcacga acagggggat ggccttctcg gggaagtggt ggtgcccgta gttgttggag
    16381 caccgggtca cccgcacgtc caggccgtgg gtgtggtggt ggctcagggc gaggagatcg
    16441 ctcgacgcct tggacgccgc gtacggcgag ctggggcgga gggggtggtc ctccggccag
    16501 gagccctcgt cgatggaccc gtagacctcg tccgtcgaga tgtggacgaa cgtgcgcgta
    16561 ccggcgcgca gcgccgcgtc gagcaggatc tgcgttccca tcacgttggt ccgggtgaac
    16621 gcggccgggt ccgtgatcga gcggtccacg tgcgactcgg cggcgaagtg cacgatctgg
    16681 tcggcgcgac gggcgaggga cctcaccagc ggcgcgtcgc agatgtcgcc ccggacgaag
    16741 gtgaagccgg gatgcgcgcg caccgggtcg aggttggccg ggttccccgc gtaggtcagc
    16801 gcgtcgagca cggtgacgga gatgtcgccg gggccctcgg gggagagcag agtgcgcacg
    16861 tagtgcgagc cgatgaaccc cgccccgccg gtgaccagga gatgagtggt cgtcatgacg
    16921 agatctgcac ctcgctgtgg tcgcccagca ggagccggtg ggcgtgcggg acggccgggg
    16981 ccggcgtcac cgtgacgttg cgtccgatca gggacgcctc gacccggcgc acccccttga
    17041 tcgacgagtc ccgcagcacg atcgagaact cgatctcgct gttctccacg cggcagtcct
    17101 ccgacaccga cgtgtacgcg ccgatgtagg agtcgctgat caccgtgccc cggccgatga
    17161 cggcggggcc gacgacgcgg gagccgcgca cgcgcgcgcc ctcctcgatg cggacccggc
    17221 cgatgatctg gctcgcctcg tccacctcgc cctcgatccg gggttcgagc gtctccagca
    17281 ccgaccggtt gacctccagc atgtccacga cgttgccggt gtccttccag tagccggaga
    17341 tcgtcgtgga gcgcacgtcg cgcccctcgt cgatgagcca ctggatggcg tgggtgatct
    17401 ccagctcccc gcgcccggag ggcttgatcg cacgcaccgc ctcatggacg gccggaccga
    17461 acaggtacac cccgacgatc gcgaggtcgc tcctggggca gggggacttc tcctccacgc
    17521 gcgcgacgtt gcccgcgtcg tccagctcgg cgacgccgaa gacggtggga ttggggacgt
    17581 gggtcagcag gatctgggcg tcggggcggt ccgacacgaa attgtccacc agttcggtga
    17641 tgccgccgac gatgaagttg tcgcccaaat acatgacgaa ttcatcgtcc cccaggaatg
    17701 agcgggatat cagcacggcg tgggcgagtc cgagcggcgc ctcctggggg atgtaggtga
    17761 cgtcgagtcc gaatttggag ccgtcgccca ccgcctcctc gatctcgtcc gccgtttcgc
    17821 ccacgatgat tcccacgtcc gtgatgccgg cttgtgcgat ggcttcgagg ccgtagaaca
    17881 gaacaggctt gttggctacc gggaccagct gtttcgccgt ggtgtgcgtg agcgggcgca
    17941 tgcgcgtacc cgcaccgccc gagaggacga gcgccttcat gtgacaagcc cccaaacaac
    18001 agcgtggaca aagtcaatgt gcacgtttct ggcaacagaa tctatgcacc gggaagtcgg
    18061 attgtctagt cttccgagat ttctctgacc ggatcggatt cacggtgccg cgcttttgtg
    18121 atgtgcgcac gccgcgctcc tgtatttctc acggattggc taggtctcac tgtggcggga
    18181 tgacccggcc ggagggtccg ggggaaattc aaccctccgg ccgggtcggc tcgtgggccc
    18241 tttcgcgagc gccggttcgc gggcggtccg cgcggggtct ccggtcagtt ggtggtcggt
    18301 tcggggtgcg cggccttcgc ctcctcggtg ggggcgccct cgcgaggggt gacgaacagc
    18361 gtggtcacca gggccagggc cagcagtccg gcgcacacgt aggaggccat cgccaggccg
    18421 tgggacatcg cctctctggc cgcgtccgcg accgcggcgg tccgcttgtc gtcggagagc
    18481 gactggatca ccgagcccgc gctgtccgtg acgaccgaac tgaaccggtc ggcctcggcg
    18541 tccttcaggc cggagtcggt gagccggtcg ttcagatcgg tggcgagggt gctgaagaac
    18601 agcgtggtca ggacggcgat acccagcgcg gagcccagtt cccgggccgc gctctggatg
    18661 cccgacccct gtccggcgct ccgcggggga acgtccacca gcacgatgtt ggtgacctgc
    18721 gccgtcgcga agcccacgcc gacgccgtag acgaacaggg cgatcgcgat cgtccaccag
    18781 gaggtgtcgg tcgcggcgat caggcccagc atcaccaggc cggcggcctc caggacgaga
    18841 ccgatccgca cctgggagag cggcgggacc gtggcggcca tgccgaaact cgctccgctg
    18901 gcgacgaagc tgcccaccgc gagcgcgacg agcgcgagtc cggcgtcgaa cgcgctgtag
    18961 tccagggtga actgcagcca cagcggcagt acggcgatga tgccgaactc gccgagtccg
    19021 accatcagcg tcacgacgtt gccgttgcgg aaggacggga tggagaagag gccgacgtcc
    19081 atcagcggct ctccgttcct gcggcccagc gccgcctgac ggcgccagaa cgcccacagg
    19141 accaccgccg acacgacgaa cgagacgcac acgggggaga ggccgccgct ccacgagagg
    19201 ccgccgacgt cgagggactc ggtggtcatc agccagccgt aggtgcgccc ctcgatcagg
    19261 gcgaacgcca gcaggccgag gccgaccgcc gacaggacgc cgccgactcc gtcgacgcgg
    19321 ccccgggttc gcggggactc ggacaggtgg acgagcgtcc cgaccatgat cagggcgacc
    19381 agggggatgt tgatgccgaa ggcccagcgc caggagatgt cggccagcca gccgccgagc
    19441 agcgggccca cggcagccgc ggcgccgatg gtcgagcccc agatggcgaa ggcctgaccc
    19501 cgggccttgc cggtgaaggt ggcgttcacc agcgccagtg aggtcgggag gatcatggcg
    19561 ccgccgaccc cctgcagtgc gcgggccagg atcagcaggc cgccgtcggg ggagagggcg
    19621 gccaccaggc tcgtgacggc gaagacgacg agaccgtaga cgaagatcct gcgggcgccg
    19681 tacaggtcgg cgaggcgtcc ggcgagcagg aggagggccg cgaaggcgat cgcgtaggac
    19741 tcctggatcc actgggcctc ggcggaatcg atcgagaggt cctcgatgat cggggccagg
    19801 atgacgttga cgatcgtgat gtcgacgacg atcagcgcca cacccaagga aactgccacc
    19861 aggccgagcc attggcgcat ggatgggggt tccgtggtgc cgttcaaggt acctccactc
    19921 tgatgtatct ttgccatgaa ggtattgagt ccgggctacg gtgtcaactc gcggggccgc
    19981 ggggccgccg acgcggatcg aggacggacg gagcatgacg atggagagag cagacctcgg
    20041 cgggctggag gtacagcgcg accggctcat ggacgggctg cgcgccttcg gtgccaacta
    20101 cgcggagttc acccagcggt tcgcgacctg gctgggcctg cactccaccg acgccgcggc
    20161 tctcgtcgag atcctctacg ccgaggacaa gggggcgccg ctgtcacccg cccggctgag
    20221 cgagcgtgtc tccctgtcgt cgggcgcgac gaccgcgctg ctgaaccgtc tcgaggcggc
    20281 cggacacatc gtgcgcaccc gtgaacacac cgaccgcagg atcgtgaccc tgcgcagcag
    20341 cccccatgtg aagccgcgcg ccgaggagtt cttcggcccc tacgccggac gcatggtcgc
    20401 cgagatgtcg cagtacaccc ccgagcagct ccagcagttc gaggacttca tcgtccacct
    20461 gcgcgagacc atggactcgc tgctcgccca cgagtacaag gagagccggc cgggcggctc
    20521 aggagcgtcc gaccggggct gacccgggag accgctcgac ctccttgttc ctgagggctc
    20581 ttgacaggcc gaactgcggc gaagaagata ctgcccatcg tggaacgtgt gtgcccgtcg
    20641 gccccgttcc ctctcccgcc gaccggttcc ggcctcctgt tccccgtgca cgtggacatc
    20701 ccgtggcacg agcggcgccg accgtgaccg gcgcgcccca cccctgaccg ccgccgtggc
    20761 atccgccgcg gcggcggcgc cgtttccggg gtggccagcc ccgaaggagc agcatgaaag
    20821 tcctcttcat cgccgcggga acgagcccgg cgggggtctt cgccctcgcc cctctcgcga
    20881 cggcggtgcg caacgcaggg cacgagatcc tggtggcggc cttcgacgag ctgaccccgg
    20941 ccgtcgcgtc cgtcggactg cccgtcgtgg ccgtcgccga cggccacacg accgagagca
    21001 tcaagggact cgaccggccg ggcggaccga tcgggttccc ctgggcaccc gagcaggaac
    21061 tgccgtacgt gggacgttgg ttcggccgcc aggcggccgt cgccatggac ggactcctgc
    21121 ggctcgccga cgtgtggcgc cccgacctcg tggtcggtgg cacggacgcc cacgccgccg
    21181 ccctgctcgg ctcccggctg ggcatcccgt acgtccgcca ggcgtgggac tggctccact
    21241 tcgacggagc ggagcgctac gcgaacgacg aactggcccc cgaactggcg caggccggac
    21301 tcgaacggct cccggcaccc gacctgttca tcgacatctg cccgccgagc ctgatcccgc
    21361 cgggcgccga gcgcggccgg ccgatgagat gggtgccggg caaccgccag cgcaagctgg
    21421 agccgtggat gtacggcaag ggcgagcgcg cccgggtgtg cgtcacgctc ggcagcttcc
    21481 gcaccgccat gccggagatg ttcgcctacc tgtgcgcact ggtggagcgg ctgacggcac
    21541 tcgacgccga gatcgtcgtc gccgccgacg agacggcctc ccggaagatc cgggagcgct
    21601 tccccggcgt acgcgccgac tgggtgccga tggagttcct cgtgcgcacc tgcgacacga
    21661 tcgtgcacgc gggcggcctc accactctca acgccatggc ggccggcacc ccgcaggtgg
    21721 tggtgaacca gttccaggcg ttcgaaccct cgctgcggct gctcgagcgg cagggatgca
    21781 gcgtggtcct gcaccgggac gacaagtccc cggacaacac cttcgacgcc tgcgagcgca
    21841 tcctctccga cgacgggtac gcgcaccggg caggtgagct ggcccgcgaa ctgggcgccc
    21901 tgcccccgcc ggccacggtc gtcggcgacc tggaggcgct ggcccgccgc tgaccccgtg
    21961 ccaccggccc accaccgccc gcgcgccgcc ctccccggcc gctccctccc cgcctgctcc
    22021 cgcctctcac cgacccccgc ccgacccagc gaccgaaagg gcccgtccgc catgcagacc
    22081 acacccccca agccgccgcc ctccgcacag gtgctgcagc tcgcgacgtc gagctggacg
    22141 gccgccgccg tgagcgccgc cgccgaactc ggcgtcgccg acgcgctggc ggacggagcc
    22201 cgcccgtccg acgagatcgc ccggagcgtc ggcgcgcacc cgcccacctg ctaccgcctg
    22261 ctgtgggcct gcgccgccat cgggctgctg gaggagagcg aggggcgggt gttcgccctc
    22321 accgaggccg gtgacgcgct ccgcggcgac tcgccacact ccatgcgcaa cttcgcccgg
    22381 tgggtcggcc tcgccgccga ccgcaacacc tgggccggcc tcgccgacag cgtccgcacc
    22441 ggcgatcccg cgttcgcgcg ggtgcacggc caggacgtgt gggagtacat gagggatcgc
    22501 gccgacgtct cgacggtctt cgacgacgcg atgaccgagg cgtcgcgtca gctgatcgcc
    22561 ccggtggtcg acgcctacga cttcggcggc accggcacgc tcgtggacgt cgcgggcggg
    22621 cacggagccc tcctcgccgc gatcctcgcc gcccacccgg gcctccgcgg cctgctgtac
    22681 gaccggcccg aggtggtgga gggggcgaag cagacgttcc aggaccgcgg ggtggacgac
    22741 cgggtggaga tcgtcgccgg cgacttcttc gactccgtgc cggagggcaa ggacgcctac
    22801 ctgctgtcga acgtcatcca tgactgggac gacgagccgt ccctgacgat cctcggcaac
    22861 tgccgccgcg cgctcgccga gggcggccgg gtgctcctcg tcgaggccgt catgccggag
    22921 cgggacgcgt cctcgccgac cgtgaccctg atggacctca acatgctcgt gctctgcggc
    22981 ggcaagcagc gcaccgagac cgagttcgcc gaactcctcg gccgcgccgg tctccgcctc
    23041 acccgcgtcg tccgggcggg actgcacagc gtcgtcgagg ccgtccgcgc ctagggtcct
    23101 tcgttcggat caggccggat cagcgagcgg cctgatccga gcgaagcccc cacccgtacc
    23161 gagccacacg gagggaccgc aagccatgcc attcatcacg cccgacaacg gatcgctcac
    23221 cgtgttcaac ctcttcgaca ccgtcgacag ggacggccag aagaccctgc tggacacgat
    23281 ggaggggatc atcaaggggg cgaactaccc ggggtggcgc tcctccaccc tgcacggcgg
    23341 cctcgacaag ccctgtgccg cgaactacat ccagtggcgc agcgtggacg atctgcagga
    23401 gcgctacgag ggtgagaact tccggcacaa cacggtgccc tacttcaagg aactgaccac
    23461 cacggtgcac ctgctgaaga ccgaggtgat cgccacccac ctgcatcccg ggctcgagcg
    23521 gatagagatc tcgccggagc gggacgactt caccgtcatc gtcgtcatgg gtgtcgagcc
    23581 cgagaaccag gccaccctcg tggacctgtt cgcgaaaccc gactccgcca tggcggacgt
    23641 gccgggatac cggtccaact ccatcctgcg cggcctcgac ggtgacttcg tcgtcaacta
    23701 cgcccagtgg gacagccgcg aggcgtacga gacgttccac ggcctgccgg aggaccggcg
    23761 tcccgcgcac acccgggcca tgcgcgcgca ggcgcgcccg ctgctgacgt cacggtcgtc
    23821 gaacacctac gaggtcgtgt tcgcgcggtc cgcgagcgac cagccgtcca ccgagcagcc
    23881 ggccggtgac cgatgaccgt gcgcgcggcg gacgacgggg cggtccgcac cgcccccggg
    23941 ccgcctcccc tccccggacc ggtccgcgtc gggccggacg acccccgcta cggcgaactg
    24001 gtgcgcggcg acaaccaccg cttcaccggc acgcccgacc acgtcgaact ggtccgctcc
    24061 accgagcagg ccgaggacgc cctccgccgg gcgctggccg ccgggcagcg ggtcgccgtg
    24121 cgcagcggtg gccactgccc ggaggcgttc gtggccggcc cggaggtcga ggtcgtcatc
    24181 gacctctccc tcatgtcgcg ggtctcctac gacccggagc tcaacgccgt cgccatcgag
    24241 gccggggcga ccgtcgggca cgtgtacaag gagctgtacc ggaactggaa cgtgaccctg
    24301 ccggccggtg tgtgcaccgc ggtcggggtc ggcggccaca tctcgggcgg cgggtacgga
    24361 ccgctgtccc ggctgcacgg cctcgtcgcg gaccacctcc acgcggtcga ggtcgtccac
    24421 gtcgaccggt ccggccgggt gcgcaccgtg atcgccaccc gggagccgga cgacccccac
    24481 cgggagctct ggtgggccca caccggcgcg ggcggcggca acttcggcat cgtcacccgc
    24541 ttctggatgc gttcccccgg ggcgagcggc accgaccccg ccggtctgct gccccggccg
    24601 cccgcctcgc tgctgaccgc gatggtgaac tggacgtggg agcagtgcga gctgcccgcg
    24661 ttcacccgga tcgtccgcaa cttcatgggc tggcacgtcg ccaacagcgc ccccggctcg
    24721 ccgtccgccg ggctgttcgc ctcgctgtgg gtcagacacc gctcgggcgg cgggctcacc
    24781 atgttcgtgc aggccgacgc cacggagccg gacgccgcgg ccgggctgga cgcgttcctc
    24841 gccgccgtcg acgagggcgt cggcgtcacc ccgttcgtcc accgcaggga actgccgtgg
    24901 ctgaccgcca gccggtacat ggggcagggc gactccggcc ccgtgatggg ggcgcggatc
    24961 aagaccaagg ccgcctatct gcgggacgtg cacaccgacg agcagatcgc caccctgtac
    25021 cggtggttcc accgcgagga ctacttcggc cgtgagtccc tgatgatgct caacggctac
    25081 ggcggcgcga tcaacgcggt cggaccggcg gacaccgcgt cggtccagcg ggactcggtg
    25141 atcaaggcgg cgtactcggc gtcctggggc gacccggagg aggacgagac gcacctgacc
    25201 tggctgcgcg ggctctacgg cgagctgtac gccggcacgg gcggggtgcc ggtgcccggc
    25261 gggccgacgg acgggtcgta catcaactac ccggacatcg acctcgccga cccggaccac
    25321 aaccggtcgg gggtgccctg gcaccagctc tactacaagg acaactacgc gacgctgcag
    25381 gccgtcaagg cggcatggga tccccgtgac gtcttccacc acgccctgtc cgtgcggctg
    25441 ccggaggacg acatgaccta ccccaccgcc cacattcccg agcactacga cttccgggcc
    25501 atctacgcgg gcgagaagga cgcgtcgccc gtccagccgt gggacatcgg ccggccgcag
    25561 cccgccctgg tggccgcgca cgacgcgggg gagatcaccg gcgacgtcct ggacgtcggc
    25621 tgcggtctcg gcgacaacgc cgccttcctc gccgggcggg gccaccgggt cacggcggtc
    25681 gacgtggccg aggcggccgt gcgggaggcg cggcgtcggg cagaggacag tggcgtcgac
    25741 gtcgagttcg ccgtcgcgga cgccacccgg ctgacggggt acgacggccg cttcgacacg
    25801 gtcgtggaca gcgcctgctt ccactcgctg tccgaggacg aacgggagcg gtacctccgc
    25861 gcgctgcgca cggcgacccg gccgggaggc aggctgcaca tgttctgctt cgcccaggag
    25921 ttcgaggccc cgttcccggg gccgcaccgg cacaccgcag cctccctgcg cgagatggtc
    25981 ggcggtgtct ggaacgtgct ctccgtggag gccgcgacct tcgccagctc cctcggcgtc
    26041 gaggacatcg ccgccctgat cgagtcggag tacccggacg gcgacgtcga cccggcccgg
    26101 ctcgacgggc tcccgctcga cgagcacggc aaggccacga tgccggtctg gcacgtgacc
    26161 gcggaacgcc gcgactgaga cgcccgtcgg cgggcgccac cggcccaccc cggtggggct
    26221 ccgcgcgtcc ccgcacccca ccccctcacc gaccccccgg agtcgccgga atgccgacaa
    26281 ctccgcggcg gtgggtcgtc ctgggcgccg aggcctgctg ggctccgcct cgccgacgtc
    26341 gcctccgccg acccccgggt cgccgtccac cgggcgggac ggcccggccg acatcacccg
    26401 cgccgccggg accgaacggc tgatgcgcgc cgtacggccg gacgtcgtcg tcaacgccgc
    26461 cgtgttcacc ggcgtggacc cctgcgaggc cgacccggcg cgcgcgtacg aggtcaacgc
    26521 cgtcggcgcg cgccatgtgg cgcgggcctg cgccgacgtc ggcgcccgct gcgtctacat
    26581 cagtaccgac tacgtcttcg acggcaccgc accagacccc tacgacgaga cggcaccgcc
    26641 ccgccccctg ctgacgtacg gcatgtccaa gctcgccggg gagggcgaga ccctgaacgc
    26701 gagccccgga cacctggtgg tgcgcaccgc cgctctgttc gggccgccgc cgccgagcca
    26761 ccggcgccgg ccgggattcg tcgagcagat cctgcgccgc gcggcggccg gacagcgcgc
    26821 cgacgtgacc gacgccctgg tcatgtcccc cacgtacacg gccgacctgg cccgcatggt
    26881 cgtcgaactg ctcgccgccg atgcggacgg cgggccctac cacgtgacca acgagggcag
    26941 cgccacctgg tacggcctcg cgcacgccgc cgtctccggc ctgggactcg gcgccctgcc
    27001 ccggcaggcc gcgcccggcg ccggtgcggc cggtcccgcg cggcccgccg ccacgcccct
    27061 gacctccgtg cggctgccgc cgcgcgtgcg gcggctcaac cgcccctggc gcgacgccct
    27121 cgcggagttc ctgcgcgacc acggaccgga cgccctggcc gcggcccggc ccgggcctcc
    27181 ccttcccgac gccccgtgac gatccgagga gacctcatgt ccgacctgcc gaactgccgt
    27241 atctgcggcg gtgccctgcg cgagttcctc gacctggggg aacagcccat gggcaacgcc
    27301 ttcgtgactc ccgggcgaca ggacgacgag gccggtgcct tccgtttccg gctcacggtc
    27361 gccgtgtgcg aggtgtgcac catggtgcag ctcaccgact acgtgcggca cgaccggatg
    27421 ttccacgccg cctatcccta ccgttcctcg cagtcgtccg tcatgagcgc ccacttcgag
    27481 aacctggcgc ggcgcttcct ccaggacgag ctgaacggca ccgacccgtt catcgtcgaa
    27541 ctcggcagca acgacggcat catgctgcgc accgtcgcca aggcgggggt gcgccacctg
    27601 ggcgtcgagc cgtgcgggga cgtcgccgag gtcggacgcg cgaacggtgt ccgcgtggtc
    27661 agcgagttct tcgacgagga cctcgccgcc cggatccgcg ccgccgacgg cacggcggac
    27721 gtcgtcttcg ccgcgaacac gttctcgcac atcgacttcc tggactccat cctgcgcggc
    27781 gtcaagaacc tgctcgcccc cggcggcgtc ttcgtcttcg aggacccgta cttcggcgac
    27841 atcgtgcaac gcgcctcgtt cgaccagatc tacgacgagc acatcttctt cttcacggca
    27901 cgttccgtcc aggacatggc cgcccgtcac ggcctcgaac tcgtcgacgt ggaactgctg
    27961 ccggtgcacg gcggcgagtt gcggtgcacc ctcgcccaca ccggcgcacg tcccgtcagc
    28021 cccgcggtgc cgcggctgct gaggcaggag gaggagcagg gtctcaccga gaccgcgacg
    28081 ctgacccgct tcgcggacgg cgtgcgggag ctcggcgaga ccctggtgac ccggctgcgc
    28141 gaactgcggg accagggcaa gcgcgtggtc ggctacgggg ccaccgccaa gagcaccacc
    28201 ctgctcaact actgcgggat cggcccggac ctggtctcct tcgtctgcga ctccaccgcc
    28261 gagaaacagg ggcggctcac cccgggcacc catatccccg tccggagctc ggaggccttc
    28321 gctgacccct accccgacta cgcgctcctg ctggcctgga accacaagga cgagatcctc
    28381 gacaaggagt ccgcgttccg cgaggcgggc gggcgatgga tccactacgt gccggacgtg
    28441 cacatcgact gagcaccccg ccgccgcacc gaccgggaac ccctcgtccg agccgtagga
    28501 gaaacgtatg cctgagatgc gcttcgtcgt cacgggctcc atcgcgaccg accatctgat
    28561 gaccttcccc ggccgtatcg gcgaacagct gatcgccggc aagctggacc gcatctccct
    28621 ctcgctgctc gtcgacgacc tggaggtccg ggacggcggt gtggccgcca acatcgccta
    28681 cggcctggcc cggctcggtc accgtccgct cctcgtcggg gcggtcggaa ccgacttcca
    28741 cgactacggc gcccgcctgg ccgccctcgg ggtggacacc tcggccgtcc gggtctccac
    28801 cacccggcac acggcccgct tcctgtgcac caccgacacc gacggcggcc agctggccac
    28861 cttctacgcc ggagcgatgg ccgaggcgtc cacgatcgac ctcggcgacg tgctgcgccg
    28921 ccacgggggc gccgacctcg tgctgatcgg cgccgacgac cccacggcga tggcccgcca
    28981 caccagggcc tgccgcgccc tcggcgtccc cttcgccgca gacccggcgc agcaactggc
    29041 ccggctcacc ggcccggaga tcagggaact ggtcgaggga gcggaccatc tgttcaccaa
    29101 cgagtacgag cgcgagctgc tgctgggcaa gacgggctgg acgccgcagg acgtgctgcg
    29161 caggaccggc gtctggatca ccacgctcgg cgacgagggc agccgcgtcg agcgggccgg
    29221 cgaacctccg gtgggggtcc cggccgtccc ggcccgcacg gtcgccgacc cgaccggagt
    29281 cggtgacgcc ttccgcgccg gctacctggc ctccctcgcg gcgggcgccg atgtggagcg
    29341 gtgcgcacgg gccgggtccg ctctggccac cctggcgctg tcggccgtcg gcacccagac
    29401 gtacgtgccc gcccccgctc acctccacga gccgccgccg cggtgacccc cgggccccgg
    29461 acccccgggc ccccgcgtcc ccgtccccgc tccaccccgc cccctccggc cgcgtgatca
    29521 cgcggccgga gggggctttt cgcgtttctc gcgttcccgc ccccgtgcgc ccgtgcgccc
    29581 gaggcgccga ggggacctag tacgcgatcc ccaccccctg cttcaccgtc ccgaggtcgt
    29641 cggtcatcgc gagcatggcg tgggcgacgt ccgcgcggcc gatgagacgg ccccggggcg
    29701 gcgtaccgcc gacgaccgtc cggtacctgc cgctgacggg cttgttctgc aggcgcggcg
    29761 gccgtacggc cgtccagtcc gtggcgctcc gggtcagctc ggcctccatc tctcgcagat
    29821 cggcgtagat gtccttgagg acggcggaga cgatgccgcg cagggcacgg tcgagcggtc
    29881 cgtcgccttc cgccccgggg ccgaccggag ccgcgctcac gaccaggaga cgccgtgtgc
    29941 cctccgcctc catggcgcgc agcaccgtac gtgtgagccg ggtcgcgacg ccggcgtcct
    30001 tgcggctgcg ggcgccgagg ccggacagca cggcgtcccg tccggccacc gcggggcgca
    30061 ccgcctccgg atcggtcagg tcggcgcgga acacctccag ctgcgtaccg gtgacggtca
    30121 gcccagcggg gttccggacg accgccgtga cgtgatgtcc cgcgtccagc gcctgccgga
    30181 cgatctcctg gccgatgcct cccgtggcac cgaacacggt gagtctcatg agtcctccag
    30241 gtctcccgag aaggtgagtg agcattcacc caccgccggt ctcctctaga gtgagtaaac
    30301 actcacccac ccgtcaaggc gggaagggcg gaaaggacgc gccatggaat ccccggggag
    30361 cacgcggcac aggccggccg aggcccggat cctcgacgcc gcctacgagc tcatgcgcac
    30421 ggtgggactg gcccgcacca cgaccaagga gatcgcccgg gcggccggtt gctcggaggc
    30481 cgcgctgtac aagtacttcg cgggcaagga ggagctgttc atccgcgtgc tggccgagag
    30541 gctgccgcgg ctcaccccgc tgctgcgcag tctcgccgcc gagcccgggc gagggacgct
    30601 ggaggacaac ctcaccgaga tcgcccgtca ggccgcgctc ttctacgagc agagcttccc
    30661 gatcgccgcg tccctccacg ccgagaccca gctcaagcga cggcacgacg acgcgatgcg
    30721 gcggatgggg tccggaccgc atctgcccat ccgggaactc gacgcctacc tgcgcgccga
    30781 gcaggagctg gggcggatcg gcaccgaagc ggacacgttc gcggcggcgt ccctgctgat
    30841 gggcgcctgc gcgcaacggg cgttcgccta cgacgcggcc caggagggtg cgcgcccccc
    30901 ggtggacgac ttcgccgccc gcctggcccg taccctgctg gccggcctgg ccggctgacg
    30961 tccgtcggcc ggaccggcgg ccgacggacg gctcctcagc cggacaccgc gtgcggccag
    31021 tgcacgagac cgccgagtgt gggagcggta cgcgtcgcct cctcccggga gtggtagacc
    31081 tcgtaactct ggcgcatgcc gctgaggtcg aagatccgga gcacccggct ggaggcggac
    31141 acgatgcgca gcgagccgtc gcgtccccgg atgcgcttcg tgaccgccac gatcatgccc
    31201 aggcccatgg aatccaggaa gggaacgaag ttgagatcga ggatgaagtg acggtgtccc
    31261 tcgtcgatga gctcgatcag tgcatcacgg atcatcggcg aggtgtggcc gtccatgtca
    31321 ccgtcgatct cgacgacggt ccagccgttc accatgtcgt agctggccat catgttctcg
    31381 tgccggatga tgttcgtccg catggccacc tccttctgcg tttccggacg gcgtcagccg
    31441 cggggccggg gtgcccgcgc gctcctcacc ccttccccgc cagccattcg gccaggacgg
    31501 cggcctggct gtggtccaca tccttggtgg cggtcagcag cacgagcccg tcgtgctccg
    31561 ccaggtcgtg cagatgcccg gccgcctcgc ggtgcccggc gtcgcgcagc tcctcgaggt
    31621 agcgacggcg gaactcggtg aagcggctcg gctcgtggcc gtaccacttt cgcagttcgc
    31681 tcgacggggc gacgtcacgc agccactcgt cgagacgcgc gtcctccttg cgcatgcccc
    31741 ggggccagac ccggtccacg aggacgcgct tgccctcctg cggtgaggtc tcctcgtaga
    31801 ccctgcggca ggcgatctgt ccgaccatga cggtgccctt ccggatcggc cgggcgaccc
    31861 ggccgcggtg cggacggcct cgctcccgtg ctgagcaggc gtatgtcccg gctcgtccat
    31921 tttatcggca gccgccggct ttcccgggcc gtgtggcgcg cggagacccg tccgggggcg
    31981 tccacgccag tcccgtgcgg actgaaagag caggtcaggg ccgtctgtga ctctctcggg
    32041 cgcctgcttc gcgagcgcat ccgcccgtcc gtgacgtcgt ggcgctcccc agcgagacca
    32101 ctgccgcccc ggcgccgccg accgcctcgc cgaggtggcc cgcgccgccc cgaccccgag
    32161 acccacggcg acggccacgg ccgcattctc gtcccggaca gcgccgacgc cgacgacgtc
    32221 atgttcaccg acgaggtctt cgccggcgcc ctggggcgtg gtccgcctgc ccggcgatga
    32281 cgtgtccctt cttcccgcgc gcggccggcc ggccggcggg agccggtcat ggcgggagcc
    32341 ggtcatggcg ggaaagtctg aatgatggtt catttctttc atggcctacc gcaagacccc
    32401 cgccgagatc agccgtctcg aagccgcgcg agagcgcctc gtcgtctgcg ccacgtccgt
    32461 ggtggcggaa gtcggctggg cccaggcgtc cgtgaccgcc gtcgcggacg cggccggcat
    32521 cgcggcgggc tccgtctacc agcacttccc ctccaaggcg gcactcgccg tcgaggtgtt
    32581 ccgacgcgcg gccggacgcg aggtcgacgt gctcggcgag gtactgcacg gccccggcgg
    32641 ccccgtcggg cgactcgccc gcggcgccca ggtcttcgcc cgccgtgccc tggagaaccg
    32701 gggcctggcc tacgcgctgc tcgcggcccc cgccgaaccc gcggtgggcg ccgagcgtct
    32761 cgacttccgg cgccgctacc gcgcgctgtt cgccgaggtg gtccgcgagg gagtggccgc
    32821 aggcgtactg cccgagcaga acgccgagat caccgccgcc gccctcaccg gcgcgatcgg
    32881 cgaagtactg gtggacccgc tcgccgcccc ggacgaaggc tccatcgagg cgctgctcac
    32941 cgacctcacc gccaccgcgc tgcgctgcgc gggcgcaccg gccgcctgac cctcatccgc
    33001 tcccggagga caccccatgc ccacgaccgg cctcgtcacc cacgaagtga ccaaccagcc
    33061 accgccgttg accggccacg acaccgcgga cgacccggtc ctcctcgaag gagtacaccg
    33121 agagggagcc gcctggcatc tggacgacct gcaccggctg ggccgcctgg ccggaagcga
    33181 ggaggcccag ggctgggcgg accaggccaa ccggcacgag cccgagctgc gcacccacga
    33241 ccgctacggg caccgcgtcg acgaggtcga cttccacccc gcctaccact cgctgatgga
    33301 cgtctcggtg agcgccggca tcgcgggcgc cgcctggacc gacgagcggc ccggcgccca
    33361 cgtggcacgg gcggcgagct tcatgctggc caccatgctg gagccgggcc atctgtgccc
    33421 ggtctccatg acgtacgccg tcgtccccgc gctgcgccac gcccccgacc tcgccaagac
    33481 ctacgagccc ctgctcacca gccgcgtcta cgatcccgga ctgcgcgtcc ccgccggcaa
    33541 gcgcggtctg ctcgccggta tgggcatgac ggagaagcag ggcggcaccg acgtccgcgc
    33601 caacaccacc gccgccaccg aacaggccga cgggaggtgg cggctgcgcg gccacaagtg
    33661 gttcaccagc gccccgatga acgacctgtt cctcgtgctc gcccaggcgc ccggcgggct
    33721 gtcctgcttc ctggtcccgc gcgtcctgcc ggacggcagc cgcaacacgt tccgcatcca
    33781 gcgcctcaag gacaagctcg gcaaccgctc caacgccagc agtgaacccg agttcgacga
    33841 caccgtggcc tggctcgtcg gcgacgaggg caagggcgtg cggaccatca tcgacatggt
    33901 gaccatgacg cggctcgact gcgtcctcgg ctccgccgcc ggcacccggg ccgcgctcgc
    33961 gcaggcagcc caccacgccc ggcaccgctc ggtgttcggc gccgagctga tcgaccagcc
    34021 cctcatgcgc aacgtcctgg ccgacctcgc gctggaatcc gaggccgcca cgaccctggc
    34081 gctgcggctg gccggtgccg ccgaccgggc ccagcgcggg gacgcggggg agcgggcctt
    34141 cctgcgcctg gccaccgccg tcggcaagta ctgggtctgc aagcgccagc ccgccgccgt
    34201 ggccgaggcc ctcgagtgcc tgggcggcaa cggctacgac gaggcgtccg ggatgccgcg
    34261 cctctaccgc gaggcgccgc tcaacggcat ctgggagggc tccggcaacg tcaacgccct
    34321 cgacatgctc agggcgttga cgcgcgaacc ggaatccctg gaggcctacc gcgcggaggt
    34381 ggagccggcg gccggggcgg accgccgcct ggacgccgcc tggcgggaac tccagggaga
    34441 gctcgtcctc accgaggacg cctcccttcg tgcccgccgg gtcatcgagc gcgcggccct
    34501 cgtgctgcag ggctcgctcc tggtccggca cgcgcccgcg ccggtcgcgg acgcgttctg
    34561 cgcgtcgcgc ctcgccggcg accggggcct cgccttcgga accctggcgc ccggcacgga
    34621 cttcgcgggt ctgctggggc ggcttcccgt gtga
//
