Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0000212.1:
Cluster 1Polyketide135117

BGC0000212, cinerubin B biosynthetic gene cluster from Streptomyces sp. SPB74. Locus 1. Full MIBiG entry.

Chemical compounds

Compound: Cinerubin B
ChemSpider ID: 66267
SMILES string: Copy to clipboard
Molecular formula:
Average molecular mass: Da
Molecular activity: Cytotoxic
Molecular target: DNA

Class-specific details

Biosynthetic class(es):
Polyketide
Polyketide subclass:
Anthracycline (cyclic)
Polyketide synthase subclass:
Type II
Starter unit:
Propionyl-CoA
Polyketide synthase / ketosynthase-encoding genes:
SSBG_00494
Genes involved in folding/cyclization:
SSBG_00488, SSBG_00497, SSBG_00505

Gene cluster description

cinerubin B (BGC0000212). Gene Cluster 1. Biosynthetic class = Polyketide. GenBank GG770539, positions 5086070-5121186. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous known gene clusters

General MIBiG information on this cluster

Complete gene cluster sequence?complete
Evidence for cluster-compound connection:Sequence-based prediction
MIxS-compliance:Unknown
Contact for this cluster:Roland Kersten (Salk Institute of Biological Studies)

Literature references

1. Kersten RD et al. (2013) Glycogenomics as a mass spectrometry-guided genome-mining method for microbial glycosylated molecules. Proc Natl Acad Sci U S A 110(47):E4407-16. doi: