BGC0000217: daunorubicin biosynthetic gene cluster from Streptomyces sp.
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Location: 1 - 8,089 nt. (total: 8,089 nt).
This entry is originally from NCBI GenBank L34880.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
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Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000217
Short description daunorubicin biosynthetic gene cluster from Streptomyces sp.
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
L34880.1
via
Compounds
  • daunorubicin
Species Streptomyces sp. [taxonomy]
References
Chemical products information
daunorubicin Evidence:
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C27H29N1O10
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AAA87614.1
  • dauE
 3 - 236 (+) aklaviketone reductase
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    • AAA87615.1
    • dauA
    		 373 - 1320 (-) cyclase/dehydrase
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      • AAA87616.1
      • dauB
      		 1350 - 2138 (-) polyketide reductase
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        • AAA87617.1
        		 2317 - 2712 (+) oxygenase
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          • AAA87618.1
          		 2709 - 3965 (+) polyketide synthase
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            • AAA87619.1
            		 4052 - 5248 (+) polyketide synthase
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              • AAA87620.1
              		 5245 - 6303 (+)
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                • AAA87621.1
                		 6314 - 7330 (+) acyltransferase
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                  • AAA87622.1
                  • dauC
                  		 7505 - 8089 (-) aklanonic acid methyltransferase
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                    Biosynthesis information
                    Annotation changelog

                    Entry version: 4

                    Date
                    Changes
                    Submitters
                    Reviewers
                    2022-10-07
                    Update chemical activity to schema version 2.11
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                    Entry version: 3

                    Date
                    Changes
                    Submitters
                    Reviewers
                    2022-09-15
                    Updated bioactivity data
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                    Entry version: 2

                    Date
                    Changes
                    Submitters
                    Reviewers
                    2019-10-16
                    Migrated from v1.4
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                    Entry version: 1

                    Date
                    Changes
                    Submitters
                    Reviewers
                    2015-06-12
                    Submitted
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    Detailed domain annotation
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