LOCUS       BGC0000218              8737 bp    DNA     linear   BCT 20-APR-1995
DEFINITION  Streptomyces peucetius daunorubicin-doxorubicin polyketide synthase
            (dnrH, dpsA-dpsF) genes, ORF5 and ORF8, complete cds.
ACCESSION   BGC0000218
VERSION     BGC0000218
KEYWORDS    .
SOURCE      Streptomyces peucetius
  ORGANISM  Streptomyces peucetius
            Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
            Streptomyces.
COMMENT     Original source text: Streptomyces peucetius (library: ATCC 29050)
            DNA.
            ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2022-11-07 17:46:35
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 8737
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..8737
                     /db_xref="taxon:1950"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces peucetius"
                     /tissue_lib="ATCC 29050"
     subregion       1..8737
                     /aStool="mibig"
                     /contig_edge="True"
                     /label="Polyketide"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..8737
                     /contig_edge="True"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            28..783
                     /gene="dnrH"
     CDS             28..783
                     /NRPS_PKS="Domain: PKS_KR (6-165). E-value: 3.7e-11. Score:
                     35.1. Matches aSDomain: nrpspksdomains_dnrH_PKS_KR.1"
                     /codon_start=1
                     /function="reductase"
                     /gene="dnrH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     205; E-value: 2.3e-62)"
                     /gene_kind="biosynthetic-additional"
                     /note="protein H; putative"
                     /product="daunorubicin-doxorubicin polyketide synthase"
                     /protein_id="AAA65202.1"
                     /sec_met_domain="adh_short_C2 (E-value: 3.1e-32, bitscore:
                     101.7, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENTQRSVIVTGGGSGIGRAVARAFAARGDRVLVVGRTAGPLAET
                     VDGHKDAHTLAVDITDPAAPEAVVREVRERLGGVVDVLVNNAATAAFGHLGELHRTAVE
                     AQVATNLVAPVLLTQALLGPLETASGLVVNIGSAGALGRRAWPGNAVYGAAKAGLDLLT
                     RSWAVELGPRGIRVVGVAPGVIGTGAGVRAGMSQEAYDGFLEAMGQRVPLGRVGRPEDV
                     AWWVVRLADPEAAYASGAVLAVDGGLSVT"
     CDS_motif       46..132
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_dnrH_0001"
                     /evalue="1.00E-07"
                     /label="PKSI-KR_m1"
                     /locus_tag="dnrH"
                     /protein_end="35"
                     /protein_start="6"
                     /score="24.6"
                     /tool="antismash"
                     /translation="SVIVTGGGSGIGRAVARAFAARGDRVLVV"
     aSDomain        46..522
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_dnrH_PKS_KR.1"
                     /evalue="3.70E-11"
                     /label="dnrH_PKS_KR.1"
                     /locus_tag="dnrH"
                     /protein_end="165"
                     /protein_start="6"
                     /score="35.1"
                     /tool="antismash"
                     /translation="SVIVTGGGSGIGRAVARAFAARGDRVLVVGRTAGPLAETVDGHKD
                     AHTLAVDITDPAAPEAVVREVRERLGGVVDVLVNNAATAAFGHLGELHRTAVEAQVATN
                     LVAPVLLTQALLGPLETASGLVVNIGSAGALGRRAWPGNAVYGAAKAGLDLLTRS"
     gene            complement(918..1865)
                     /gene="dpsF"
     CDS             complement(918..1865)
                     /NRPS_PKS="Domain: Polyketide_cyc2 (7-149). E-value:
                     2.2e-18. Score: 58.9. Matches aSDomain:
                     nrpspksdomains_dpsF_Polyketide_cyc2.1"
                     /NRPS_PKS="Domain: Polyketide_cyc2 (156-311). E-value:
                     2e-08. Score: 26.5. Matches aSDomain:
                     nrpspksdomains_dpsF_Polyketide_cyc2.2"
                     /codon_start=1
                     /function="cyclase"
                     /gene="dpsF"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1128:cyclase/dehydrase (Score: 410.6; E-value:
                     7e-125)"
                     /gene_kind="biosynthetic-additional"
                     /note="protein F; putative"
                     /product="daunorubicin-doxorubicin polyketide synthase"
                     /protein_id="AAA65203.1"
                     /transl_table=11
                     /translation="MSELPLQQTEHEIHTSAAPDAVFAVLADARAWPAVFPPSVHVEQV
                     EHTGSSERIRIWATANGSLRTWTSRRELDERARRIRFRQEVSAHPVAAMGGEWIVEEAG
                     DGGTRVRLTHDFRAVDDDPETIGWIHRAVDRNSEAELASLRTALERPDGTAPTTFEDTV
                     VVRGRAEDVYDFLHRSDLWKKRLSHVARIAVKEEEPGLQHMEMDTLTADGSVHTTASVR
                     VCFPERRVIVYKQLRTPPLLALHLGRWSVRPADDGDGIAVTSAHTVSVARSAIPGVLGA
                     GASETDAVDFVRRALGRNSLLTLEAARQYAESSA"
     aSDomain        complement(933..1397)
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_dpsF_Polyketide_cyc2.2"
                     /domain_subtype="Polyketide_cyc2"
                     /evalue="2.00E-08"
                     /label="dpsF_Polyketide_cyc2.2"
                     /locus_tag="dpsF"
                     /protein_end="311"
                     /protein_start="156"
                     /score="26.5"
                     /tool="antismash"
                     /translation="TTFEDTVVVRGRAEDVYDFLHRSDLWKKRLSHVARIAVKEEEPGL
                     QHMEMDTLTADGSVHTTASVRVCFPERRVIVYKQLRTPPLLALHLGRWSVRPADDGDGI
                     AVTSAHTVSVARSAIPGVLGAGASETDAVDFVRRALGRNSLLTLEAARQYA"
     aSModule        933..1844
                     /domains="nrpspksdomains_dpsF_Polyketide_cyc2.1"
                     /domains="nrpspksdomains_dpsF_Polyketide_cyc2.2"
                     /incomplete
                     /locus_tags="dpsF"
                     /tool="antismash"
                     /type="unknown"
     aSDomain        complement(1419..1844)
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_dpsF_Polyketide_cyc2.1"
                     /domain_subtype="Polyketide_cyc2"
                     /evalue="2.20E-18"
                     /label="dpsF_Polyketide_cyc2.1"
                     /locus_tag="dpsF"
                     /protein_end="149"
                     /protein_start="7"
                     /score="58.9"
                     /tool="antismash"
                     /translation="QTEHEIHTSAAPDAVFAVLADARAWPAVFPPSVHVEQVEHTGSSE
                     RIRIWATANGSLRTWTSRRELDERARRIRFRQEVSAHPVAAMGGEWIVEEAGDGGTRVR
                     LTHDFRAVDDDPETIGWIHRAVDRNSEAELASLRTALE"
     gene            complement(1895..2680)
                     /gene="dpsE"
     CDS             complement(1895..2680)
                     /NRPS_PKS="Domain: PKS_KR (7-159). E-value: 5.5e-15. Score:
                     47.5. Matches aSDomain: nrpspksdomains_dpsE_PKS_KR.1"
                     /codon_start=1
                     /function="reductase"
                     /gene="dpsE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     263.1; E-value: 3.9e-80)"
                     /gene_kind="biosynthetic-additional"
                     /note="protein E; putative"
                     /product="daunorubicin-doxorubicin polyketide synthase"
                     /protein_id="AAA65204.1"
                     /sec_met_domain="adh_short (E-value: 1.3e-41, bitscore:
                     131.8, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEAADRVALVTGGTSGIGLAVVRKLAQDGTRVFLCARDESAITG
                     TVKELQASGLEVDGAPCDVRSTADVDRLVQTARNRFGPIDIVVNNAGRGGGGVTAEITD
                     DLWLDVVDTNLSGAFRVTRAVLTGGAMQEHGWGRIISIASTGGKQGVALGAPYSASKSG
                     LIGFTKAVALELAKTGITVNAVCPGYVETPMAQGVRQRYAAFWGITEDDVLEKFQAKIP
                     LGRYSMPEEVAGMVHYLASDSADSITAQAINVCGGLGSY"
     aSDomain        complement(2204..2659)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_dpsE_PKS_KR.1"
                     /evalue="5.50E-15"
                     /label="dpsE_PKS_KR.1"
                     /locus_tag="dpsE"
                     /protein_end="159"
                     /protein_start="7"
                     /score="47.5"
                     /tool="antismash"
                     /translation="VALVTGGTSGIGLAVVRKLAQDGTRVFLCARDESAITGTVKELQA
                     SGLEVDGAPCDVRSTADVDRLVQTARNRFGPIDIVVNNAGRGGGGVTAEITDDLWLDVV
                     DTNLSGAFRVTRAVLTGGAMQEHGWGRIISIASTGGKQGVALGAPYSA"
     CDS_motif       complement(2576..2653)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_dpsE_0001"
                     /evalue="4.70E-07"
                     /label="PKSI-KR_m1"
                     /locus_tag="dpsE"
                     /protein_end="35"
                     /protein_start="9"
                     /score="22.5"
                     /tool="antismash"
                     /translation="LVTGGTSGIGLAVVRKLAQDGTRVFL"
     CDS             2872..3261
                     /codon_start=1
                     /note="ORF8; putative"
                     /product="anthraquinol monooxygenase"
                     /protein_id="AAA65205.1"
                     /transl_table=11
                     /translation="MPQPEPNDAGSGSVTFVNRFTLSGSAEDFEAAFAETAEFLCRRPG
                     FRWHALLVPADTGPGSADARPQYVNIAVWDDEASFRAAVAHPEFPAHAAALRALSTSEP
                     TLYRHRQIRVAPDVPAVSGPGGRTT"
     gene            3258..4517
                     /gene="dpsA"
     CDS             3258..4517
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (4-394). E-value:
                     1.8e-53. Score: 173.8. Matches aSDomain:
                     nrpspksdomains_dpsA_PKS_KS.1"
                     /codon_start=1
                     /function="3-oxoacyl:ACP synthase"
                     /gene="dpsA"
                     /gene_functions="biosynthetic (rule-based-clusters) T2PKS:
                     t2ks"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 476.4; E-value:
                     1.4e-144)"
                     /gene_kind="biosynthetic"
                     /note="protein A"
                     /product="daunorubicin-doxorubicin polyketide synthase"
                     /protein_id="AAA65206.1"
                     /sec_met_domain="t2ks (E-value: 1.3e-223, bitscore: 731.7,
                     seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNRRIVITGIGVVAPGAVGTKPFWELLLSGTTATRAISTFDATPF
                     RSRIAAECDFDPVAAGLSAEQARRLDRAGQFALVAGQEALADSGLRIDEDSAHRVGVCV
                     GTAVGCTQKLESEYVALSAGGAHWVVDPGRGSPELYDYFVPSSLAAEVAWLAGAEGPVN
                     IVSAGCTSGIDSIGYACELIREGTVDAMVAGGVDAPIAPITVACFDAIRATSDHNDTPE
                     TASRPFSRSRNGFVLGEGGAIVVLEEAEAAVRRGARIYAEIGGYASRGNAYHMTGLRAD
                     GAEMAAAITAALDEARRDPSDVDYVNAHGTATKQNDRHETSAFKRSLGEHAYRVPISSI
                     KSMIGHSLGAVGSLEVAATALAVEYGVIPPTANLHDPDPELDLDYVPLTAREKRVRHAL
                     TVGSGFGGFQSAMLLSRLER"
     aSDomain        3270..4439
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_dpsA_PKS_KS.1"
                     /domain_subtype="Iterative-KS"
                     /evalue="1.80E-53"
                     /label="dpsA_PKS_KS.1"
                     /locus_tag="dpsA"
                     /protein_end="394"
                     /protein_start="4"
                     /score="173.8"
                     /tool="antismash"
                     /translation="IVITGIGVVAPGAVGTKPFWELLLSGTTATRAISTFDATPFRSRI
                     AAECDFDPVAAGLSAEQARRLDRAGQFALVAGQEALADSGLRIDEDSAHRVGVCVGTAV
                     GCTQKLESEYVALSAGGAHWVVDPGRGSPELYDYFVPSSLAAEVAWLAGAEGPVNIVSA
                     GCTSGIDSIGYACELIREGTVDAMVAGGVDAPIAPITVACFDAIRATSDHNDTPETASR
                     PFSRSRNGFVLGEGGAIVVLEEAEAAVRRGARIYAEIGGYASRGNAYHMTGLRADGAEM
                     AAAITAALDEARRDPSDVDYVNAHGTATKQNDRHETSAFKRSLGEHAYRVPISSIKSMI
                     GHSLGAVGSLEVAATALAVEYGVIPPTANLHDPDPELDLDYVPLTAREKR"
     gene            4523..5800
                     /gene="dpsB"
     CDS             4523..5800
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (86-422). E-value:
                     3e-25. Score: 80.8. Matches aSDomain:
                     nrpspksdomains_dpsB_PKS_KS.1"
                     /codon_start=1
                     /function="unknown"
                     /gene="dpsB"
                     /gene_functions="biosynthetic (rule-based-clusters) T2PKS:
                     t2clf"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093:Beta-ketoacyl synthase (Score: 612.5; E-value:
                     4.5e-186)"
                     /gene_kind="biosynthetic"
                     /note="protein B"
                     /product="daunorubicin-doxorubicin polyketide synthase"
                     /protein_id="AAA65207.1"
                     /sec_met_domain="t2clf (E-value: 5.5e-186, bitscore: 607.3,
                     seeds: 26, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGTAARTASSQLHASPAGRRGLRGRAVVTGLGIVAPNGLGVGAY
                     WDAVLNGRNGIGPLRRFTGDGRLGRLAGEVSDFVPEDHLPKRLLAQTDPMTQYALAAAE
                     WALRESGCSPSSPLEAGVITASASGGFAFGQRELQNLWSKGPAHVSAYMSFAWFYAVNT
                     GQIAIRHDLRGPVGVVVAEQAGGLDALAHARRKVRGGAELIVSGAVDSSLCPYGMAAQV
                     KSGRLSGSDNPTAGYLPFDRRAAGHVPGEGGAILTVEDAERAAERGAKVYGSIAGYGAS
                     FDPPPGSGRPSALARAVETALADAGLDGSDIAVVFADGAAVPELDAAEAEALASVFGPR
                     RVPVTVPKTLTGRLYSGAGPLDVATALLALRDEVVPATAHVDPDPDLPLDVVTGRPRSL
                     ADARAALLVARGYGGFNSALVVRGAA"
     aSDomain        4781..5788
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_dpsB_PKS_KS.1"
                     /domain_subtype="Iterative-KS"
                     /evalue="3.00E-25"
                     /label="dpsB_PKS_KS.1"
                     /locus_tag="dpsB"
                     /protein_end="422"
                     /protein_start="86"
                     /score="80.8"
                     /tool="antismash"
                     /translation="RLLAQTDPMTQYALAAAEWALRESGCSPSSPLEAGVITASASGGF
                     AFGQRELQNLWSKGPAHVSAYMSFAWFYAVNTGQIAIRHDLRGPVGVVVAEQAGGLDAL
                     AHARRKVRGGAELIVSGAVDSSLCPYGMAAQVKSGRLSGSDNPTAGYLPFDRRAAGHVP
                     GEGGAILTVEDAERAAERGAKVYGSIAGYGASFDPPPGSGRPSALARAVETALADAGLD
                     GSDIAVVFADGAAVPELDAAEAEALASVFGPRRVPVTVPKTLTGRLYSGAGPLDVATAL
                     LALRDEVVPATAHVDPDPDLPLDVVTGRPRSLADARAALLVARGYGGFNSALVVR"
     gene            5797..6858
                     /gene="dpsC"
     CDS             5797..6858
                     /codon_start=1
                     /function="unknown"
                     /gene="dpsC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PKS-like: ksIII"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1084:3-oxoacyl-(acyl carrier protein) synthase III
                     (Score: 118.5; E-value: 5.1e-36)"
                     /gene_kind="biosynthetic"
                     /note="protein C"
                     /product="daunorubicin-doxorubicin polyketide synthase"
                     /protein_id="AAA65208.1"
                     /sec_met_domain="ksIII (E-value: 2.1e-96, bitscore: 311.7,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVPQGAPGDLYVAGCGVWLPPPVTTEQALAAGHCDRRLASSTRM
                     LSVAVADKETPAEMAALAAQTALDRSGVAPAHVDLVLHASLYFQGHHLWAPSSYVQRVA
                     VGNRCPAMEVRQVSNGGMAALELARAYLLAAPDRVAALITTGDRMHPPGFDRWSSDPGT
                     VYADGGTALVLSRQGGFARLRSLVTVSEPVLEGMHRGGHPFGPPSPEEQRAVDLDAHKR
                     AYVAEAGSSFSVARVSAGQEEALTGALEAAGAGLDDISRVVLPHMGWRRLSAAYFNKWH
                     IQPERTTWEFGRRTGHLGGGDPIAGFDHLVGSGRLAPGELCLLVSVGAGFSWSCAVVEL
                     LERPSWAAAPAAR"
     gene            6869..7882
                     /gene="dpsD"
     CDS             6869..7882
                     /NRPS_PKS="Domain: PKS_AT (8-290). E-value: 2e-65. Score:
                     212.9. Matches aSDomain: nrpspksdomains_dpsD_PKS_AT.1"
                     /codon_start=1
                     /function="acyltransferase"
                     /gene="dpsD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PKS_AT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1021:malonyl CoA-acyl carrier protein transacylase
                     (Score: 251.6; E-value: 2.9e-76)"
                     /gene_kind="biosynthetic-additional"
                     /note="protein D; putative"
                     /product="daunorubicin-doxorubicin polyketide synthase"
                     /protein_id="AAA65209.1"
                     /sec_met_domain="PKS_AT (E-value: 3.2e-66, bitscore: 212.9,
                     seeds: 1682, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDAPAILLMFPGQGSQHARMAVGLYGSEPAFTAAMDEVFDAYDDA
                     GDSEGGRLRADWLSDHPAVPLDHVTRSQPLLFAVDYALGRMVMATTGRPWALLGHSVGE
                     MAAAALAGVFTLRDAAGLLLDRVRRLAQAPPGGMLAVAAAEDVLGPYLGNGEVVVAAVN
                     SPRQTILAGPVASLAGVARALREAGLTCREVPSLTAFHSPMLAPIAAGAAERFASTRVA
                     PSIPLRSGYRPGAVTGQLAADPSYWAGHPLETVRFWPALDAMLGSRTGVVCLETGPGQG
                     LSTIARRHPTVRFGKNSVVPLLPPQAGTAEVDRTSVAAALAAVREQGTVLSGRPGR"
     CDS_motif       6890..6943
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_dpsD_0001"
                     /evalue="8.80E-06"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="dpsD"
                     /protein_end="25"
                     /protein_start="7"
                     /score="18.1"
                     /tool="antismash"
                     /translation="LMFPGQGSQHARMAVGLY"
     aSDomain        6893..7738
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_dpsD_PKS_AT.1"
                     /evalue="2.00E-65"
                     /label="dpsD_PKS_AT.1"
                     /locus_tag="dpsD"
                     /protein_end="290"
                     /protein_start="8"
                     /score="212.9"
                     /tool="antismash"
                     /translation="MFPGQGSQHARMAVGLYGSEPAFTAAMDEVFDAYDDAGDSEGGRL
                     RADWLSDHPAVPLDHVTRSQPLLFAVDYALGRMVMATTGRPWALLGHSVGEMAAAALAG
                     VFTLRDAAGLLLDRVRRLAQAPPGGMLAVAAAEDVLGPYLGNGEVVVAAVNSPRQTILA
                     GPVASLAGVARALREAGLTCREVPSLTAFHSPMLAPIAAGAAERFASTRVAPSIPLRSG
                     YRPGAVTGQLAADPSYWAGHPLETVRFWPALDAMLGSRTGVVCLETGPGQGLSTIARRH
                     P"
     CDS_motif       7085..7117
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_dpsD_0002"
                     /evalue="4.30E-03"
                     /label="PKSI-AT-M_m2"
                     /locus_tag="dpsD"
                     /protein_end="83"
                     /protein_start="72"
                     /score="10.2"
                     /tool="antismash"
                     /translation="QPLLFAVDYAL"
     CDS_motif       7145..7246
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_dpsD_0003"
                     /evalue="3.90E-15"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="dpsD"
                     /protein_end="126"
                     /protein_start="92"
                     /score="47.9"
                     /tool="antismash"
                     /translation="RPWALLGHSVGEMAAAALAGVFTLRDAAGLLLDR"
     CDS_motif       7346..7384
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_dpsD_0004"
                     /evalue="6.40E-04"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="dpsD"
                     /protein_end="172"
                     /protein_start="159"
                     /score="13.0"
                     /tool="antismash"
                     /translation="AAVNSPRQTILAG"
     CDS_motif       7604..7639
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_dpsD_0005"
                     /evalue="8.00E-03"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="dpsD"
                     /protein_end="257"
                     /protein_start="245"
                     /score="9.9"
                     /tool="antismash"
                     /translation="YWAGHPLETVRF"
     CDS_motif       7847..7867
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_dpsD_0006"
                     /evalue="2.50E+01"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="dpsD"
                     /protein_end="333"
                     /protein_start="326"
                     /score="-1.0"
                     /tool="antismash"
                     /translation="QGTVLSG"
     CDS             complement(7860..8720)
                     /codon_start=1
                     /function="unknown"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 95.5; E-value:
                     5.8e-29)"
                     /gene_kind="biosynthetic-additional"
                     /note="ORF5"
                     /protein_id="AAA65210.1"
                     /sec_met_domain="PCMT (E-value: 1e-08, bitscore: 24.4,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQDSSYKEQVTQAFDQSSSTYDRLGVEFFTPMGRPLVEISEPVTG
                     ERVLDIGCGRGACLFPAAEKVGPQGRVHGIDIAPGMIEEARKEAAERGLRNIALDVMDA
                     ETPELPARSFDLVMGSYSVIFLPDAVGALARYAGILDHGGRIAFTSPVFRAGTFPFLPP
                     EFTPLIPQALLEHLPEQWRPEALVRRFNSWLERAEDLLRTLERCGYTSVAVTDEPVRMT
                     ALSSEAWVDWSHTQGMRLLWQNLPQAQRTELRARLVEGLDKLSDATGALAIDVPVRFVT
                     ARVAH"
ORIGIN
        1 tccaccggcg gtgcctagcc tcgccgcatg gagaacacac agcgatccgt gatcgtgacc
       61 ggcggcggct ccggcatcgg acgagccgtc gcccgcgcct tcgccgcccg gggcgaccgc
      121 gtcctcgtcg tgggcaggac cgccggtccg ctggccgaga cggtggacgg gcacaaggac
      181 gcgcacacgt tggccgtgga catcaccgac cccgcggcgc cggaggcggt cgtccgggag
      241 gtgcgcgagc ggctcggcgg cgtggtcgac gtgctcgtga acaatgccgc cacggccgcc
      301 ttcgggcacc tgggagagct gcaccgcacc gcggtggagg cacaggtggc cacgaacctc
      361 gtggcccccg tgctgctcac ccaggccctg ctcggccccc tggagaccgc ttccggcctg
      421 gtggtgaaca tcggttcggc gggcgcactc ggccggcggg cctggccggg gaacgcggtg
      481 tacggggcgg ccaaggccgg cctggacctg ctgacgcggt cctgggccgt ggaactcggt
      541 ccccgcggca ttcgcgtggt cggtgtcgcc ccgggagtga tcgggacggg cgcgggggtc
      601 cgggccggga tgtcccagga ggcgtacgac gggttcctgg aagccatggg gcagcgcgtc
      661 ccgctcggcc gtgtgggccg gcccgaggac gtcgcgtggt gggtggtgcg gctcgccgat
      721 cccgaagccg cgtacgccag cggtgccgtg ctggccgtgg acgggggtct ctcggtgacg
      781 tgaggcccgc ccggccggac acccgcaggt cgccctccgc tcgccggagg gcgacctgcg
      841 ggtgtccggc cagggacgcg gcgggccccg cccctaggga gtcgggacag ggcccgtgcg
      901 ggctcgggac gctcgcctca ggcgctggac tcggcgtact gcctggccgc ttccagggtc
      961 agcagactgt tgcggcccag ggcccggcgg acgaagtcca cggcgtccgt ctcactcgcc
     1021 cccgcaccga ggacgccggg gatcgccgag cgggccacgg acacggtgtg ggccgacgtg
     1081 acggcgatcc cgtccccgtc gtcggcggga cggaccgacc aacggccgag atggagcgcg
     1141 agcagcggcg gcgtgcgcag ctgcttgtag acgatgacgc ggcgttcggg gaagcacact
     1201 cgcaccgacg cggtggtgtg caccgagccg tccgcggtga gggtgtccat ctccatgtgc
     1261 tggagccccg gttcctcctc cttgaccgcg atccgcgcga cgtgggagag ccgcttcttc
     1321 cagaggtcgc tgcggtggag gaagtcgtag acgtcctcgg cacggccgcg gacgacgacg
     1381 gtgtcctcga aggtcgtcgg cgcggtgccg tcgggtcgtt ccagcgcggt gcgcagggac
     1441 gccagttccg cttcgctgtt gcggtccacg gcccggtgga tccagccgat cgtctccggg
     1501 tcgtcgtcca cggcccggaa gtcgtgcgtc agccgcaccc gggtgccgcc gtcgccggct
     1561 tcctcgacga tccattcgcc gcccatggcg gcgacgggat gggcggacac ctcctgccgg
     1621 aaacggatgc gccgggcccg ctcgtcgagc tcgcgccgcg acgtccaggt gcgcagcgag
     1681 ccgttggcgg tggcccagat gcggatgcgc tcgctggagc cggtgtgctc gacctgttcg
     1741 acgtggacac tgggcgggaa cacggcgggc caggcccgtg cgtcggccag cacggcgaac
     1801 acggcgtccg gcgcggcgga ggtgtggatc tcgtgctcgg tctgctgaag cggcaactcg
     1861 gacatctgcc ttcctgagct cgggtcgcgg acggtcagta gctgccgagg ccaccacaga
     1921 cgttgatggc ctgggccgtg atcgagtcgg cgctgtcgga ggccaggtag tgcaccatcc
     1981 cggccacctc ctcgggcatc gagtagcgtc cgagggggat cttcgcctgg aacttctcca
     2041 ggacgtcgtc ctcggtgatc ccccagaagg cggcgtagcg ctgccgcacg ccctgtgcca
     2101 tgggcgtctc gacgtacccg gggcagacgg cgttgacggt gatgcccgtc ttggccagct
     2161 ccagcgcgac ggccttcgtg aagccgatca ggccgctctt ggaggcggag tagggggcgc
     2221 cgagggccac tccctgcttg ccgccggtgg aggcgatgct gatgatccgg ccccagccgt
     2281 gctcctgcat ggcgccgccg gtgaggacgg cgcgggtgac ccggaaggcc ccgctgaggt
     2341 tggtgtcgac gacgtcgagc cacaggtcgt ccgtgatctc ggcggtcacg cctccaccgc
     2401 cgcggccggc gttgttgacg acgatgtcga tcggcccgaa gcggttccgg gccgtttgga
     2461 ccagccggtc gacgtcggcg gtgctccgca cgtcgcaggg cgcgccgtcc acctccagtc
     2521 ccgatgcctg aagttccttc acggtgccgg tgatggcgct ctcgtcacga gcgcacagga
     2581 acacccgggt cccgtcctgg gcgagcttgc gcaccaccgc gagaccgatg ccgctggttc
     2641 ccccggtgac gagtgcgacc cggtcggctg cctcggacat ggtcctccct tcgacggagg
     2701 gcccaccctc acatctcgcg ctcgagccgc gcttgacgac ccggcttcca gagggggtcg
     2761 agcggcgccg cagagcctcg gagtccggcg tgaccgcacc tgtgcggact cggccgcacc
     2821 gtctcaccga cgtccacccc acacctggac caacggaccc gtggagcagc gatgccacag
     2881 ccagaaccga acgacgccgg ctccgggtcg gtgacgttcg tcaaccgatt caccctgagc
     2941 ggatccgccg aggacttcga ggcggcgttc gccgaaacgg ccgagttcct gtgtcgccgg
     3001 cccggcttcc gctggcacgc cctgctggtg ccggccgaca ccggtcccgg ctcggcggac
     3061 gcccgcccgc agtacgtgaa catcgcggtc tgggacgacg aggcctcctt ccgcgccgcc
     3121 gtggcacacc cggagttccc ggcccacgcg gccgcccttc gggccctgag caccagcgaa
     3181 ccgaccctgt accggcaccg tcagatccgt gtcgcgccgg acgtcccggc cgtgagcggg
     3241 cccggagggc ggacgacgtg aaccggcgga tcgtcatcac cgggatcggc gtggtggctc
     3301 ccggcgccgt cgggaccaag ccgttctggg agctgctgct gtccggaacc accgccaccc
     3361 gcgccatcag cactttcgac gccacgccct tccgttcccg tatcgccgcc gagtgcgact
     3421 tcgatccggt ggcggcgggg ctgtccgcgg agcaggcccg gcgcctcgac cgggccgggc
     3481 agttcgcgct ggtcgccggt caggaggcgc tcgccgacag cgggctgcga atcgatgagg
     3541 actccgcgca ccgggtcggg gtgtgcgtgg gcaccgccgt cggctgcacg cagaaactgg
     3601 agtccgagta cgtcgctctc agcgcgggcg gagcgcactg ggtcgtggac cccggccggg
     3661 ggtcgcccga gctgtacgac tacttcgtgc cgagttccct cgccgccgaa gtggcctggc
     3721 tcgccggggc ggaggggccc gtgaacatcg tctcggccgg gtgcacctcg gggatcgact
     3781 ccatcgggta cgcctgcgag ctcatccgcg aggggacggt ggacgccatg gtcgcgggag
     3841 gcgtggacgc acccatcgcg ccgatcacgg tggcctgctt cgacgccatc agggcgacct
     3901 ccgaccacaa cgacaccccc gagaccgcct cgcgtccctt cagccgcagc cgcaacggct
     3961 ttgtgctggg cgagggcggt gcgatcgtgg tcctggaaga ggcggaggcg gccgtgcgca
     4021 ggggcgcgcg gatctacgcc gagatcggcg ggtacgcctc acgcggcaac gcgtaccaca
     4081 tgaccgggct gcgcgcagac ggcgccgaga tggcggcggc gatcaccgcg gccctcgacg
     4141 aggcccgccg cgacccctcg gacgtggact acgtcaacgc ccacggaacg gcgacgaagc
     4201 agaacgaccg gcacgagacc tccgcgttca agcgctccct gggggagcac gcgtaccggg
     4261 tgcccatcag ctccatcaag tcgatgatcg gtcactccct gggcgctgtc ggctcgctcg
     4321 aagtggcggc gaccgcactg gccgtggagt acggggtgat cccgccgacc gcgaatctgc
     4381 acgacccgga tccggaactc gacctggact acgtgccgct gacggcacga gaaaagcggg
     4441 tgcggcacgc gctgacggtg ggcagcggct tcggcggctt ccagagcgcc atgctgctga
     4501 gccgtctcga gaggtgagct ccatgacagg taccgcggca cggaccgcgt cttcgcagct
     4561 ccacgcatcg cccgcgggcc gacggggcct caggggccgc gcggtggtga cgggtctcgg
     4621 gatcgtcgcc cccaacgggc tgggggtggg cgcgtattgg gacgccgtcc tgaacggccg
     4681 caacggcatc ggaccgctgc ggcggttcac cggcgacggc cgcctgggcc ggctggccgg
     4741 tgaggtgagc gacttcgtcc ccgaggacca tctgccgaag cggctgctgg cgcagaccga
     4801 tccgatgacc cagtacgcgc tggccgccgc ggagtgggcc ctgcgggagt ccggctgctc
     4861 cccgtcctcg ccgctggagg cgggggtgat cacggccagc gcgtccggcg gcttcgcctt
     4921 cggccagcgg gagttgcaga atctttggag caagggaccg gcccacgtca gcgcctacat
     4981 gtcgttcgcc tggttctacg ccgtcaacac cgggcagatc gccatccggc acgatctgcg
     5041 cggcccggtc ggcgtggtgg tggccgagca ggcgggcggc ctcgacgccc tcgcccacgc
     5101 tcgccgcaag gtccggggcg gagccgagct gatcgtctcg ggcgccgtgg actcgtcgct
     5161 gtgcccgtac ggcatggcgg cccaggtgaa gtccggccgg ctgagcggct cggacaaccc
     5221 gacagccggg tatctgccgt tcgaccggcg ggcggccgga catgtgcccg gcgagggagg
     5281 cgcgatcctc accgtcgagg acgcggagcg ggccgccgag cggggcgcga aagtgtacgg
     5341 gtcgatcgcc gggtacggcg cgagcttcga cccgccgccc ggctccggcc gcccctccgc
     5401 cctcgcccgt gccgtcgaga cggcgctggc cgacgccggg ctggacggct ccgacatagc
     5461 cgtggtgttc gccgacggcg cggccgtccc cgaactggac gcagccgagg cggaggctct
     5521 ggcgtcggtc ttcgggccgc gccgggtccc ggtgaccgtc cccaagactc tcaccggccg
     5581 gctgtattcg ggcgccgggc cgctggacgt ggcgaccgcg ctgctggcgc tgcgggacga
     5641 ggtggtcccg gcgaccgccc acgtcgaccc cgacccggac ctgccgctcg acgtggtgac
     5701 cgggcggccc cggtccctgg ccgacgccag ggcggccctc ctcgtcgccc gcggctacgg
     5761 gggcttcaac agcgctctgg tggtccgggg ggcggcgtga gcgtgccgca gggggcgccc
     5821 ggggaccttt acgtggccgg ttgcggcgtc tggctgcccc cgccggtgac cacggaacag
     5881 gccctggccg ccggccactg cgaccgcagg ctcgcctcct cgacgcggat gctgtcggtg
     5941 gcggtcgccg acaaggagac accggccgaa atggcggcct tggcggccca gaccgctctg
     6001 gaccgctccg gcgtcgcacc ggcccacgtc gacctcgtcc tgcacgccag tctgtacttc
     6061 caggggcacc atctgtgggc tccctcctcc tacgtccagc gggtggccgt cgggaaccgc
     6121 tgccccgcca tggaggtgcg gcaggtgtcc aacggcggca tggccgccct ggaactggcc
     6181 cgcgcgtacc tgcttgccgc cccggaccgg gtggccgctc tcatcacgac aggcgaccgg
     6241 atgcatccgc cgggcttcga ccgctggagc agcgaccccg gcacggtgta cgccgacggt
     6301 ggtaccgccc tcgtgctgtc ccggcagggc ggtttcgccc ggctgcgcag cctggtgacg
     6361 gtctccgaac cggtgctgga gggcatgcac cggggcgggc acccgttcgg cccgccgtct
     6421 ccggaggagc agcgggccgt ggacctggac gcgcacaagc gggcgtacgt ggccgaggcg
     6481 ggaagctcgt tcagcgtcgc ccgggtctcg gcgggccagg aggaggctct gaccggcgcg
     6541 ctggaggcgg ccggggccgg actcgacgac atcagccggg tcgtgctgcc gcacatgggg
     6601 tggcgccggc tgagcgccgc ctacttcaac aagtggcaca tccaacccga gcggaccact
     6661 tgggagttcg ggcggcggac cggccacctg gggggcggtg acccgatcgc cgggttcgac
     6721 caccttgtgg gctccggccg cctcgccccg ggggagctgt gtctgctggt cagcgtcggc
     6781 gccggcttca gctggtcgtg cgccgtcgtg gagttgctgg aacgcccgtc gtgggcggcc
     6841 gccccggccg cccggtgagg agcccgtcat ggatgcgccc gcgattctcc tgatgttccc
     6901 cgggcagggg tcccagcatg cgcggatggc cgtcggcctg tacggatccg aaccggcctt
     6961 cacggccgcc atggacgagg tcttcgacgc gtacgacgac gccggcgaca gtgagggcgg
     7021 gcggctgcgt gccgactggc tgagcgacca tccggccgtg ccattggacc acgtcacccg
     7081 gtcccagccg ttgttgttcg cggtggacta cgccctcggc cggatggtga tggccacgac
     7141 gggccggccg tgggccctgc tcgggcacag cgtcggcgaa atggcggcgg ccgcgctcgc
     7201 cggggtgttc acgctgcgcg acgcggccgg cctcctgctg gaccgggtgc gacggctggc
     7261 ccaggcaccg cccgggggaa tgctggcggt cgccgcggcc gaggacgtgc tgggcccgta
     7321 tctcgggaat ggggaggtgg tggtcgcggc cgtcaactcg ccccgccaga ccatcctcgc
     7381 cggacccgtc gcatcgctcg ccggggtcgc ccgggcgctg cgggaggcag ggcttacgtg
     7441 ccgtgaggtg ccctcgctga ccgccttcca cagtccgatg ctggccccga tcgcggcggg
     7501 ggcggccgag cggttcgcat ccacgcgcgt ggcgccgtcc atccccctcc gctccgggta
     7561 ccggccgggt gcggtgaccg ggcaactggc cgccgacccg tcgtactggg ccgggcatcc
     7621 cctggagacg gtccgcttct ggccggcact ggacgcgatg ctcggctccc gcacgggcgt
     7681 cgtctgcctg gagacggggc cggggcaggg gctgagcacc atcgcccgcc gccatccgac
     7741 ggtgcggttc gggaagaact cggtggtgcc gctgctgccg ccgcaggccg gcaccgccga
     7801 ggtggaccgg acgtccgtgg cggcggcgct ggccgcggtg cgcgagcagg gcaccgtgct
     7861 cagtgggcga cccgggcggt gacgaagcgg acgggcacgt cgatggcgag ggccccggtg
     7921 gcgtcgctca gcttgtcgag tccctcgacg agccgtgcgc gcagttccgt tcgctgggcc
     7981 tgcgggaggt tctgccacag cagacgcatg ccctgggtgt gggaccagtc cacccacgcc
     8041 tcgctggaca gggccgtcat ccgcaccggc tcgtcggtga cggcgaccga ggtgtagccg
     8101 cagcgttcca gggtgcggag gagatcctcg gcccgctcca gccagctgtt gaaccgccgg
     8161 accagcgcct cgggccgcca ctgctcgggc aggtgctcca gcagcgcctg cgggatgagc
     8221 ggggtgaact ccggtggcag gaacgggaac gtgccggcgc ggaagaccgg gctggtgaac
     8281 gcgatcctgc cgccgtggtc caggattccg gcgtagcgcg ccagcgcccc caccgcgtcc
     8341 ggcaggaaga tgacgctgta gctccccatg accaggtcga aggagcgcgc cgggagttcg
     8401 ggcgtctccg cgtccatcac atcgagggcg atattccgca gaccgcgttc ggcggcttcc
     8461 ttgcgagctt cctcgatcat tccgggagca atgtcgattc cgtggacgcg cccctgagga
     8521 ccgacctttt ccgcagccgg aaaaaggcat gcgccgcgcc cgcagccgat gtcgagcact
     8581 cgttcaccgg tgaccggctc cgagatttcc accaggggcc gacccatggg cgtgaagaat
     8641 tccactccca gtcggtcgta ggtcgacgac gactggtcga aggcctgagt tacctgctct
     8701 ttgtaggacg aatcctgcac cgtcggctcc tgcctct
//
