BGC0000222: FD-594 biosynthetic gene cluster from Streptomyces sp. TA-0256
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Location: 1 - 43,026 nt. (total: 43,026 nt).
This entry is originally from NCBI GenBank AB469194.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
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resistance
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000222
Short description FD-594 biosynthetic gene cluster from Streptomyces sp. TA-0256
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
AB469194.1
via
Compounds
  • FD-594
Species Streptomyces sp. TA-0256 [taxonomy]
References
Chemical products information
FD-594 Evidence:
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C47H56O20
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • BAJ52667.1
 1 - 611 (-) hypothetical protein
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    • BAJ52668.1
    		 527 - 1369 (-) hypothetical protein
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      • BAJ52669.1
      • pnxR1
      		 1494 - 1997 (-) putative transcriptional regulator
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        • BAJ52670.1
        • pnxT
        		 2184 - 4040 (+) putative transporter
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          • BAJ52671.1
          • pnxO1
          		 4068 - 5054 (-) putative dehydrogenase
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            • BAJ52672.1
            • pnxE1
            		 5227 - 5685 (+) hypothetical protein
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              • BAJ52673.1
              • pnxMT1
              		 5758 - 6387 (+) putative methyltransferase
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                • BAJ52674.1
                • pnxR2
                		 6558 - 8465 (+) putative transcriptional regulator
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                  • BAJ52675.1
                  • pnxO2
                  		 8465 - 9724 (+) putative cytochrome P450
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                    • BAJ52676.1
                    • pnxF
                    		 9809 - 10354 (+) hypothetical protein
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                      • BAJ52677.1
                      • pnxO3
                      		 10440 - 11657 (-) putative cytochrome P450
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                        • BAJ52678.1
                        • pnxJ
                        		 11829 - 12833 (-) putative acyltransferase
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                          • BAJ52679.1
                          • pnxK
                          		 13057 - 13380 (+) putative polyketide cyclase
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                            • BAJ52680.1
                            • pnxL
                            		 13377 - 13901 (+) putative polyketide cyclase
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                              • BAJ52681.1
                              • pnxA
                              		 13898 - 15169 (+) putative ketoacyl synthase
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                                • BAJ52682.1
                                • pnxB
                                		 15166 - 16419 (+) putative ketoacyl synthase
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                                  • BAJ52683.1
                                  • pnxC
                                  		 16470 - 16727 (+) putative acyl carrier protein
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                                    • BAJ52684.1
                                    • pnxD
                                    		 16730 - 17203 (+) putative polyketide cyclase
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                                      • BAJ52685.1
                                      • pnxE2
                                      		 17200 - 17658 (+) hypothetical protein
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                                        • BAJ52686.1
                                        • pnxG
                                        		 17679 - 18428 (+) putative 3-oxoacyl-ACP reductase
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                                          • BAJ52687.1
                                          • pnxH
                                          		 18430 - 18759 (+) hypothetical protein
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                                            • BAJ52688.1
                                            • pnxI
                                            		 18756 - 19088 (+) hypothetical protein
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                                              • BAJ52689.1
                                              • pnxM
                                              		 19100 - 19348 (+) hypothetical protein
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                                                • BAJ52690.1
                                                • pnxS2
                                                		 19401 - 20444 (+) putative dTDP-glucose 4,6-dehydratase
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                                                  • BAJ52691.1
                                                  • pnxS1
                                                  		 20441 - 21508 (+) putative glucose-1-phosphate thymidylyltransferase
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                                                    • BAJ52692.1
                                                    • pnxS3
                                                    		 21598 - 23091 (+) putative NDP-hexose 2,3-dehydratase
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                                                      • BAJ52693.1
                                                      • pnxS4
                                                      		 23088 - 24101 (+) putative NDP-hexose-3-ketoreductase
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                                                        • BAJ52694.1
                                                        • pnxO4
                                                        		 24121 - 25746 (+) putative polyketide hydroxylase
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                                                          • BAJ52695.1
                                                          • pnxN
                                                          		 25743 - 26438 (+) putative AHL-lactonase
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                                                            • BAJ52696.1
                                                            • pnxO5
                                                            		 26555 - 27814 (-) putative cytochrome P450
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                                                              • BAJ52697.1
                                                              • pnxGT1
                                                              		 27825 - 29129 (-) putative glycosyltransferase
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                                                                • BAJ52698.1
                                                                • pnxP
                                                                		 29262 - 30581 (-) putative amidohydrolase
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                                                                  • BAJ52699.1
                                                                  • pnxO6
                                                                  		 30776 - 32278 (+) putative FAD-binding monooxygenase
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                                                                    • BAJ52700.1
                                                                    • pnxMT2
                                                                    		 32359 - 33168 (+) putative methyltransferase
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                                                                      • BAJ52701.1
                                                                      • pnxGT2
                                                                      		 33318 - 34484 (+) putative glycosyltransferase
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                                                                        • BAJ52702.1
                                                                        • pnxQ
                                                                        		 34577 - 35005 (-) hypothetical protein
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                                                                          • BAJ52703.1
                                                                          • pnxS5
                                                                          		 35239 - 36015 (+) putative NDP-hexose-4-ketoreductase
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                                                                            • BAJ52704.1
                                                                            • pnxU
                                                                            		 36012 - 37013 (+) putative 3-oxoacyl-ACP synthase III
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                                                                              • BAJ52705.1
                                                                              • pnxV
                                                                              		 37086 - 37343 (+) putative acyl carrier protein
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                                                                                • BAJ52706.1
                                                                                • pnxO7
                                                                                		 37432 - 38388 (-) putative dehydrogenase
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                                                                                  • BAJ52707.1
                                                                                  • pnxO8
                                                                                  		 38423 - 38815 (-) hypothetical protein
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                                                                                    • BAJ52708.1
                                                                                    • pnxW
                                                                                    		 38904 - 39638 (-) putative 3-ketoacyl-ACP reductase
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                                                                                      • BAJ52709.1
                                                                                      		 39819 - 40232 (+) hypothetical protein
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                                                                                        • BAJ52710.1
                                                                                        		 40257 - 41474 (+) hypothetical protein
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                                                                                          • BAJ52711.1
                                                                                          		 41464 - 41880 (+) hypothetical protein
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                                                                                            • BAJ52712.1
                                                                                            		 42011 - 42469 (+) hypothetical protein
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                                                                                              Biosynthesis information
                                                                                              Annotation changelog

                                                                                              Entry version: 4

                                                                                              Date
                                                                                              Changes
                                                                                              Submitters
                                                                                              Reviewers
                                                                                              2022-10-07
                                                                                              Update chemical activity to schema version 2.11
                                                                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                                              Entry version: 3

                                                                                              Date
                                                                                              Changes
                                                                                              Submitters
                                                                                              Reviewers
                                                                                              2022-09-15
                                                                                              Updated bioactivity data
                                                                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                                              Entry version: 2

                                                                                              Date
                                                                                              Changes
                                                                                              Submitters
                                                                                              Reviewers
                                                                                              2019-10-16
                                                                                              Migrated from v1.4
                                                                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                              2019-10-16
                                                                                              Updated compound(s) information (NPAtlas curation)
                                                                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                                              Entry version: 1

                                                                                              Date
                                                                                              Changes
                                                                                              Submitters
                                                                                              Reviewers
                                                                                              2015-06-12
                                                                                              Submitted
                                                                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                              Detailed domain annotation
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