BGC0000222: FD-594 biosynthetic gene cluster from Streptomyces sp. TA-0256
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Location: 1 - 43,026 nt. (total: 43,026 nt).
This entry is originally from NCBI GenBank AB469194.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
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Gene details
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General
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NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000222
Short description FD-594 biosynthetic gene cluster from Streptomyces sp. TA-0256
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide
Loci NCBI GenBank: AB469194.1
Compounds
  • FD-594
Species Streptomyces sp. TA-0256 [taxonomy]
References
Chemical products information
FD-594
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C47H56O20
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • BAJ52667.1
 1 - 611 (-) hypothetical protein
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  • BAJ52668.1
 527 - 1369 (-) hypothetical protein
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  • BAJ52669.1
  • pnxR1
 1494 - 1997 (-) putative transcriptional regulator
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  • BAJ52670.1
  • pnxT
 2184 - 4040 (+) putative transporter
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  • BAJ52671.1
  • pnxO1
 4068 - 5054 (-) putative dehydrogenase
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  • BAJ52672.1
  • pnxE1
 5227 - 5685 (+) hypothetical protein
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  • BAJ52673.1
  • pnxMT1
 5758 - 6387 (+) putative methyltransferase
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  • BAJ52674.1
  • pnxR2
 6558 - 8465 (+) putative transcriptional regulator
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  • BAJ52675.1
  • pnxO2
 8465 - 9724 (+) putative cytochrome P450
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  • BAJ52676.1
  • pnxF
 9809 - 10354 (+) hypothetical protein
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  • BAJ52677.1
  • pnxO3
 10440 - 11657 (-) putative cytochrome P450
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  • BAJ52678.1
  • pnxJ
 11829 - 12833 (-) putative acyltransferase
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  • BAJ52679.1
  • pnxK
 13057 - 13380 (+) putative polyketide cyclase
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  • BAJ52680.1
  • pnxL
 13377 - 13901 (+) putative polyketide cyclase
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  • BAJ52681.1
  • pnxA
 13898 - 15169 (+) putative ketoacyl synthase
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  • BAJ52682.1
  • pnxB
 15166 - 16419 (+) putative ketoacyl synthase
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  • BAJ52683.1
  • pnxC
 16470 - 16727 (+) putative acyl carrier protein
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  • BAJ52684.1
  • pnxD
 16730 - 17203 (+) putative polyketide cyclase
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  • BAJ52685.1
  • pnxE2
 17200 - 17658 (+) hypothetical protein
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  • BAJ52686.1
  • pnxG
 17679 - 18428 (+) putative 3-oxoacyl-ACP reductase
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  • BAJ52687.1
  • pnxH
 18430 - 18759 (+) hypothetical protein
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  • BAJ52688.1
  • pnxI
 18756 - 19088 (+) hypothetical protein
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  • BAJ52689.1
  • pnxM
 19100 - 19348 (+) hypothetical protein
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  • BAJ52690.1
  • pnxS2
 19401 - 20444 (+) putative dTDP-glucose 4,6-dehydratase
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  • BAJ52691.1
  • pnxS1
 20441 - 21508 (+) putative glucose-1-phosphate thymidylyltransferase
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  • BAJ52692.1
  • pnxS3
 21598 - 23091 (+) putative NDP-hexose 2,3-dehydratase
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  • BAJ52693.1
  • pnxS4
 23088 - 24101 (+) putative NDP-hexose-3-ketoreductase
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  • BAJ52694.1
  • pnxO4
 24121 - 25746 (+) putative polyketide hydroxylase
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  • BAJ52695.1
  • pnxN
 25743 - 26438 (+) putative AHL-lactonase
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  • BAJ52696.1
  • pnxO5
 26555 - 27814 (-) putative cytochrome P450
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  • BAJ52697.1
  • pnxGT1
 27825 - 29129 (-) putative glycosyltransferase
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  • BAJ52698.1
  • pnxP
 29262 - 30581 (-) putative amidohydrolase
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  • BAJ52699.1
  • pnxO6
 30776 - 32278 (+) putative FAD-binding monooxygenase
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  • BAJ52700.1
  • pnxMT2
 32359 - 33168 (+) putative methyltransferase
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  • BAJ52701.1
  • pnxGT2
 33318 - 34484 (+) putative glycosyltransferase
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  • BAJ52702.1
  • pnxQ
 34577 - 35005 (-) hypothetical protein
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  • BAJ52703.1
  • pnxS5
 35239 - 36015 (+) putative NDP-hexose-4-ketoreductase
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  • BAJ52704.1
  • pnxU
 36012 - 37013 (+) putative 3-oxoacyl-ACP synthase III
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  • BAJ52705.1
  • pnxV
 37086 - 37343 (+) putative acyl carrier protein
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  • BAJ52706.1
  • pnxO7
 37432 - 38388 (-) putative dehydrogenase
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  • BAJ52707.1
  • pnxO8
 38423 - 38815 (-) hypothetical protein
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  • BAJ52708.1
  • pnxW
 38904 - 39638 (-) putative 3-ketoacyl-ACP reductase
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  • BAJ52709.1
 39819 - 40232 (+) hypothetical protein
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  • BAJ52710.1
 40257 - 41474 (+) hypothetical protein
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  • BAJ52711.1
 41464 - 41880 (+) hypothetical protein
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  • BAJ52712.1
 42011 - 42469 (+) hypothetical protein
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Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
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