BGC0000232: hatomarubigin A biosynthetic gene cluster from Streptomyces sp. 2238-SVT4
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Location: 1 - 34,927 nt. (total: 34,927 nt).
This entry is originally from NCBI GenBank AB524586.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
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resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000232
Short description hatomarubigin A biosynthetic gene cluster from Streptomyces sp. 2238-SVT4
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
AB524586.1
via
Compounds
  • hatomarubigin A
  • hatomarubigin B
  • hatomarubigin C
  • hatomarubigin D
Species Streptomyces sp. 2238-SVT4 [taxonomy]
References
Chemical products information
hatomarubigin A Evidence:
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C20H16O5
Chemical database entries
PubCHEM
hatomarubigin B Evidence:
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C20H16O5
Chemical database entries
PubCHEM
hatomarubigin C Evidence:
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C20H18O5
Chemical database entries
PubCHEM
hatomarubigin D Evidence:
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C41H36O10
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • BAJ07838.1
368 - 850 (+) putative alanine rich protein
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    • BAJ07839.2
    • hrbR1
    1709 - 1915 (-) putative regulatory protein
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      • BAJ07840.1
      • hrbA
      2557 - 3402 (+) hypothetical protein
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        • BAJ07841.1
        • hrbB
        3641 - 3979 (+) putative cyclase
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          • BAJ07842.1
          • hrbC
          3976 - 5247 (+) putative ketosynthase
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            • BAJ07843.1
            • hrbD
            5281 - 5604 (+) hypothetical protein
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              • BAJ07844.1
              • hrbE
              5612 - 6826 (+) putative chain length determinant factor
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                • BAJ07845.1
                • hrbF
                6866 - 7570 (+) putative dehydrogenase-methyltransferase
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                  • BAJ07846.1
                  • hrbG
                  7861 - 9903 (+) putative oxygenase-reductase
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                    • BAJ07847.1
                    • hrbH
                    9917 - 11038 (+) putative oxygenase
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                      • BAJ07848.1
                      • hrbI
                      11126 - 11914 (+) putative reductase
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                        • BAJ07849.1
                        • hrbJ
                        11960 - 12640 (+) putative oxygenase
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                          • BAJ07850.1
                          • hrbK
                          12674 - 13300 (+) putative oxygenase
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                            • BAJ07851.1
                            • hrbL
                            13339 - 14415 (+) putative oxygenase
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                              • BAJ07852.1
                              • hrbM
                              14523 - 14786 (+) putative acyl carrier protein
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                                • BAJ07853.1
                                • hrbN
                                14789 - 15697 (+) putative hydrolase
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                                  • BAJ07854.1
                                  • hrbO
                                  15732 - 16517 (+) putative ketoreductase
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                                    • BAJ07855.1
                                    • hrbP
                                    16536 - 17471 (+) putative aromatase
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                                      • BAJ07856.1
                                      • hrbQ
                                      17501 - 18340 (+) putative phosphopantetheinyl transferase
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                                        • BAJ07857.1
                                        • hrbR
                                        18376 - 19758 (+) putative oxygenase
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                                          • BAJ07858.1
                                          • hrbS
                                          19901 - 20665 (+) putative ketoacyl reductase
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                                            • BAJ07859.1
                                            • hrbT
                                            20662 - 21966 (+) putative transporter
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                                              • BAJ07860.1
                                              • hrbU
                                              21986 - 22990 (+) putative O-methyltransferase
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                                                • BAJ07861.1
                                                • hrbV
                                                23212 - 24003 (+) putative short-chain dehydrogenase/reductase
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                                                  • BAJ07862.1
                                                  • hrbW
                                                  24125 - 24706 (+) putative reductase
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                                                    • BAJ07863.1
                                                    • hrbX
                                                    24769 - 25902 (+) putative oxygenase
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                                                      • BAJ07864.1
                                                      • hrbR2
                                                      25943 - 26545 (-) putative transcriptional regulator
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                                                        • BAJ07865.1
                                                        • hrbY
                                                        26627 - 27724 (+) putative oxidoreductase
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                                                          • BAJ07866.1
                                                          • hrbR3
                                                          27827 - 28549 (-) putative repressor-response regulator
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                                                            • BAJ07867.1
                                                            • hrbZ1
                                                            29339 - 30253 (-) putative N5,N10- methylenetetrahydromethanopterin reductase
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                                                              • BAJ07868.1
                                                              • hrbZ2
                                                              30360 - 31364 (-) putative aldo/keto reductase
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                                                                • BAJ07869.1
                                                                33303 - 33464 (+) putative truncated S-adenosylmethionine synthase
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                                                                  • BAJ07870.1
                                                                  33521 - 34531 (+) putative carbohydrate kinase
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                                                                    Biosynthesis information
                                                                    Annotation changelog

                                                                    Entry version: 4

                                                                    Date
                                                                    Changes
                                                                    Submitters
                                                                    Reviewers
                                                                    Update chemical activity to schema version 2.11
                                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                    Entry version: 3

                                                                    Date
                                                                    Changes
                                                                    Submitters
                                                                    Reviewers
                                                                    Updated bioactivity data
                                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                    Entry version: 2

                                                                    Date
                                                                    Changes
                                                                    Submitters
                                                                    Reviewers
                                                                    Migrated from v1.4
                                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                    Updated compound(s) information (NPAtlas curation)
                                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                    Entry version: 1

                                                                    Date
                                                                    Changes
                                                                    Submitters
                                                                    Reviewers
                                                                    Submitted
                                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                    Detailed domain annotation
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