LOCUS       BGC0000232             34927 bp    DNA     linear   BCT 01-JUL-2010
DEFINITION  Streptomyces sp. 2238-SVT4 hatomarubigin biosynthesis gene cluster
            (orf1, hrbR1, hrbA, hrbB, hrbC, hrbD, hrbE, hrbF, hrbG, hrbH, hrbI,
            hrbJ, hrbK, hrbL, hrbM, hrbN, hrbO, hrbP, hrbQ, hrbR, hrbS, hrbT,
            hrbU, hrbV, hrbW, hrbX, hrbR2, hrbY, hrbR3, hrbZ1, hrbZ2, orf2,
            orf3), complete cds.
ACCESSION   BGC0000232
VERSION     BGC0000232
KEYWORDS    .
SOURCE      Streptomyces sp. 2238-SVT4
  ORGANISM  Streptomyces sp. 2238-SVT4
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 13:13:44
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..34927
                     /db_xref="taxon:681626"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces sp. 2238-SVT4"
                     /strain="2238-SVT4"
     protocluster    1..34927
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[3975:6826]"
                     /cutoff="20000"
                     /detection_rule="(t2ks and t2clf)"
                     /neighbourhood="35000"
                     /product="T2PKS"
                     /protocluster_number="1"
                     /t2pks_malonyl_elongations="8|9 (Score: 705.4; E-value:
                     4e-215)"
                     /t2pks_molecular_weights="acetyl-CoA_8 (Da): 406.468"
                     /t2pks_molecular_weights="acetyl-CoA_9 (Da): 448.505"
                     /t2pks_product_classes="angucycline"
                     /t2pks_starter_units="acetyl-CoA (Score: 0.0; E-value: 0)"
                     /tool="antismash"
     proto_core      3976..6826
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(t2ks and t2clf)"
                     /neighbourhood="35000"
                     /product="T2PKS"
                     /protocluster_number="1"
                     /t2pks_malonyl_elongations="8|9 (Score: 705.4; E-value:
                     4e-215)"
                     /t2pks_molecular_weights="acetyl-CoA_8 (Da): 406.468"
                     /t2pks_molecular_weights="acetyl-CoA_9 (Da): 448.505"
                     /t2pks_product_classes="angucycline"
                     /t2pks_starter_units="acetyl-CoA (Score: 0.0; E-value: 0)"
     cand_cluster    1..34927
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(t2ks and t2clf)"
                     /kind="single"
                     /product="T2PKS"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..34927
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0000232"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..34927
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T2PKS"
                     /region_number="1"
                     /rules="(t2ks and t2clf)"
                     /subregion_numbers="1"
                     /tool="antismash"
     CDS             368..850
                     /codon_start=1
                     /note="orf1"
                     /product="putative alanine rich protein"
                     /protein_id="BAJ07838.1"
                     /transl_table=11
                     /translation="MTQPPHDEPTASSPDELREQVEQTREELGQTVEALAAKTDVQARA
                     QEKAAEVKEQATAKAGELKEQATVKAGELKAKATDLAHQVQDRLPDPVKDKAAQAAGQA
                     RTKAAQAGQVWEEKAPEPLRQKTAQGAQLARDNRKVLLAAAGVAVVVWLACRRRKG"
     gene            complement(1709..1915)
                     /gene="hrbR1"
     CDS             complement(1709..1915)
                     /codon_start=1
                     /gene="hrbR1"
                     /product="putative regulatory protein"
                     /protein_id="BAJ07839.2"
                     /transl_table=11
                     /translation="MTIRLAVTGDEALLIDVQDPRPDVQLSEAANDGEKGSGLKYARLL
                     GATVSCFMSEDARCKTACCRTSD"
     gene            2557..3402
                     /gene="hrbA"
     CDS             2557..3402
                     /codon_start=1
                     /gene="hrbA"
                     /product="hypothetical protein"
                     /protein_id="BAJ07840.1"
                     /transl_table=11
                     /translation="MPSSSYEANQCDSHRCRRAALDGGGRRPAARGRLCRECFSLLSAG
                     IRDLPRLYAECEEALSGGAAAGVREKTSGGSPSRGLVFNGFAAEARTRIVTTLGSWCGL
                     VADQRAVPPPVRQVGALANFLLTHLTWLATHPAAGELTAEVARAAGFARRAADPSSVQR
                     FTVGPCVVRECDGALSATIRGGRAGGTQVQCTVHPDHRWGEHEWAQLRRETLRSSPPTG
                     EHWLTAPDIARLWNTPTGTVYRLASEHKWRRISRSGRTYYAENDVAASLSRRKERAVRR
                     "
     misc_feature    2656..2658
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            3641..3979
                     /gene="hrbB"
     CDS             3641..3979
                     /codon_start=1
                     /gene="hrbB"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1225:Polyketide synthesis cyclase (Score: 150.9;
                     E-value: 1.7e-46)"
                     /gene_functions="biosynthetic-additional (t2pks) CYC
                     C4-C17/C2-C19 (Score: 183.0; E-value: 1.3e-56)"
                     /gene_kind="biosynthetic-additional"
                     /product="putative cyclase"
                     /protein_id="BAJ07841.1"
                     /transl_table=11
                     /translation="MHSTLIVARMNPKEFGHVADLFRKFDETEMPHLMGTRRRQLFHYQ
                     GLYFHLQDFDYLGSTADRARIQRARKDPRFIRISDDLKPYIQAYDPATWRSPADAMATR
                     FYQWVGAS"
     gene            3976..5247
                     /gene="hrbC"
     CDS             3976..5247
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (54-396). E-value:
                     1.6e-53. Score: 174.0. Matches aSDomain:
                     nrpspksdomains_hrbC_PKS_KS.1"
                     /codon_start=1
                     /gene="hrbC"
                     /gene_functions="biosynthetic (rule-based-clusters) T2PKS:
                     t2ks"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 480.3; E-value:
                     8.9e-146)"
                     /gene_functions="biosynthetic-additional (t2pks) KS (Score:
                     778.9; E-value: 2.5e-237)"
                     /gene_kind="biosynthetic"
                     /product="putative ketosynthase"
                     /protein_id="BAJ07842.1"
                     /sec_met_domain="t2ks (E-value: 4.3e-246, bitscore: 807.6,
                     seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNGRRAVITGLEVLAPGGVGAKDFWSLLSEGRTATRGITFFDPAP
                     FRSRVAAEIDFAPEAHGLHPQEIRRMDRAAQFAVVTARGALRDSGLELEGYAPHRVGVT
                     VGTAVGATMGLDEEYRVVSDGGRLDLVDHTYAVPHLYNYLVPSSFAAEVAWAVSAEGPN
                     SVVSTGCTSGIDAVGYAVELIREGSADVMVAGASDAPISPITMACFDAIKATTPRHDEP
                     QKASRPFDGTRNGFVLGEGAAFFVLEELESARRRNAHIYAEIAGYATRSNAYHMTGLRP
                     DGAEMAEAIRSALDEARMNPEEIDYINAHGSGTKQNDRHETAAFKKSLGSHARATPVSS
                     IKSMVGHSLGAIGSIEIAASTLAMAYNLVPPTANLHTPDPECDLDYVPLTAREHRTDTV
                     LTVGSGFGGFQSAMVLARPERNAA"
     aSDomain        4138..5163
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_hrbC_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="1.60E-53"
                     /label="hrbC_PKS_KS.1"
                     /locus_tag="hrbC"
                     /protein_end="396"
                     /protein_start="54"
                     /score="174.0"
                     /tool="antismash"
                     /translation="DFAPEAHGLHPQEIRRMDRAAQFAVVTARGALRDSGLELEGYAPH
                     RVGVTVGTAVGATMGLDEEYRVVSDGGRLDLVDHTYAVPHLYNYLVPSSFAAEVAWAVS
                     AEGPNSVVSTGCTSGIDAVGYAVELIREGSADVMVAGASDAPISPITMACFDAIKATTP
                     RHDEPQKASRPFDGTRNGFVLGEGAAFFVLEELESARRRNAHIYAEIAGYATRSNAYHM
                     TGLRPDGAEMAEAIRSALDEARMNPEEIDYINAHGSGTKQNDRHETAAFKKSLGSHARA
                     TPVSSIKSMVGHSLGAIGSIEIAASTLAMAYNLVPPTANLHTPDPECDLDYVPLTAREH
                     RT"
     gene            5281..5604
                     /gene="hrbD"
     CDS             5281..5604
                     /codon_start=1
                     /gene="hrbD"
                     /product="hypothetical protein"
                     /protein_id="BAJ07843.1"
                     /transl_table=11
                     /translation="MSAVLLILRLAGGWRLSPVRASLQISAARSPVGRLSSAMAWLSTA
                     SMTSGRIGTTGRPAAVVVKPLSAWANSHNWTRSPDSSTPCSPGRAPTGTKRSQPHRRGL
                     RKK"
     gene            5612..6826
                     /gene="hrbE"
     CDS             5612..6826
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (68-362). E-value:
                     2.6e-32. Score: 104.1. Matches aSDomain:
                     nrpspksdomains_hrbE_PKS_KS.1"
                     /codon_start=1
                     /gene="hrbE"
                     /gene_functions="biosynthetic (rule-based-clusters) T2PKS:
                     t2clf"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093:Beta-ketoacyl synthase (Score: 664.7; E-value:
                     6.6e-202)"
                     /gene_functions="biosynthetic-additional (t2pks) CLF 8|9
                     (Score: 705.4; E-value: 4e-215)"
                     /gene_kind="biosynthetic"
                     /product="putative chain length determinant factor"
                     /protein_id="BAJ07844.1"
                     /sec_met_domain="t2clf (E-value: 5.5e-209, bitscore: 684.9,
                     seeds: 26, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVSAVVTGLGVVAPNGLGAQEYWAAARVGTSAIGRISRFDPTQY
                     PSRLAGEIHGFVAEDHLPNRLLPQTDRMTRLALVAADWALEDAGIDPRELPAFDMGVVT
                     SSASGGFEFGQGELQRLWSQGSEYVSAYQSFAWFYAVNSGQISIRHNMRGPSGVVVSDQ
                     AGGLDAVAQARRQIRRGTPLIVSGGVDASLCPWGWVAQLTSGLLSSDDDPATAYLPFDR
                     RASGHVPGEGGAILIVERRDLAAARGARVYGEIAGYGATFDPRPGSDRPPALRAAIEAA
                     LADAGADAADVDVVFANGAAMPELDRVEADAINAVFGARQVPVTVPKTATGSLYSGAAA
                     LDLATVFLAIEEGLIPPTVNTEPDEGYGLDLVVGRPRTAEIRTALVLARGHRGFNSAMV
                     VRSAD"
     aSDomain        5816..6697
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_hrbE_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="2.60E-32"
                     /label="hrbE_PKS_KS.1"
                     /locus_tag="hrbE"
                     /protein_end="362"
                     /protein_start="68"
                     /score="104.1"
                     /tool="antismash"
                     /translation="QTDRMTRLALVAADWALEDAGIDPRELPAFDMGVVTSSASGGFEF
                     GQGELQRLWSQGSEYVSAYQSFAWFYAVNSGQISIRHNMRGPSGVVVSDQAGGLDAVAQ
                     ARRQIRRGTPLIVSGGVDASLCPWGWVAQLTSGLLSSDDDPATAYLPFDRRASGHVPGE
                     GGAILIVERRDLAAARGARVYGEIAGYGATFDPRPGSDRPPALRAAIEAALADAGADAA
                     DVDVVFANGAAMPELDRVEADAINAVFGARQVPVTVPKTATGSLYSGAAALDLATVFLA
                     IEEGLIPPTVNTE"
     gene            6866..7570
                     /gene="hrbF"
     CDS             6866..7570
                     /codon_start=1
                     /gene="hrbF"
                     /product="putative dehydrogenase-methyltransferase"
                     /protein_id="BAJ07845.1"
                     /transl_table=11
                     /translation="MPVASDAPPDFGRSDVEAVVVTTASLPKPNAAELADTVAARWQAG
                     PWPAEQVALSVFIGGDGTSVLTYAQWSSRGALEESLRDHGSVSWANAPGALLGEGADSG
                     VRTTGPLPFGIYRTVRGTAVTEENPVPVSFPVAFFTMADEASAAAWVDGLLSAEEENEG
                     DERAYPDAIAANFHVSLDGTQVLVLSEWLSAEAASQHIADVWDPILAHFGGDAGALYRH
                     HTTLNALEKTAD"
     gene            7861..9903
                     /gene="hrbG"
     CDS             7861..9903
                     /codon_start=1
                     /gene="hrbG"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050:monooxygenase FAD-binding (Score: 434.7; E-value:
                     8.7e-132)"
                     /gene_functions="biosynthetic-additional (t2pks) OXY
                     (Score: 609.3; E-value: 1.2e-185)"
                     /gene_kind="biosynthetic-additional"
                     /product="putative oxygenase-reductase"
                     /protein_id="BAJ07846.1"
                     /transl_table=11
                     /translation="MSGPERGGAHAGGGPVEPYSHALEPDVLIVGAGPAGLLLAGDLAS
                     DGVRVTVVDALTEPMTESRASTLHARTMEVLAARDLLERLGPPPPGGPGHFGGLRLDLA
                     EADPQHRHAGQWKCPQTLLERELARWSTESGALLLRGHRLVALTQTAHRVEVELKSADG
                     SRVAARAPYLVGCDGERSTVRELAGFTLAGRSAGREMLRADVAGIDVPDRRFERLPRGM
                     ATAARWPDGSTRLMVHLYGHRPQPRSGPPSFAEVADAWATVTGEDVGHGTPLWLNAFDD
                     TSRQATRYRQGRVLLAGDAAHLQMPVGGQALNLGLQDASDLGGKLAARVLGRAGDEVLE
                     SYHDSRHPVGARTLSNIRAQTLLLLGDQQVEPLRSIFGELLEDRAVRRHLAGMISGLDT
                     AAPEPGVPRPTPAPAPSRPHLTPERTTVSRLIDKTALVTGSSRGIGRAIATRLAAEGAL
                     VAVHYASNADAALETVELIEKDGGRAFPVRAELGAPGDVHQLFLGLEKGLKERIGETRL
                     DILVNNAGAITPVGQQPEDTTPEEFDHLFAVNARAPFFIVQRALGIIPTGGRIINISSG
                     LTRFSNPEQTAYAMTKGAIEQLSLHLARHLAPRLITVNSVAPGITDNGGAVFDIPEAVE
                     QMAQLSAFKRVGKAEDVADVVTFLATDEARWITGAFIDATGGTLL"
     gene            9917..11038
                     /gene="hrbH"
     CDS             9917..11038
                     /codon_start=1
                     /gene="hrbH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083:oxidoreductase (Score: 148; E-value: 6.4e-45)"
                     /gene_kind="biosynthetic-additional"
                     /product="putative oxygenase"
                     /protein_id="BAJ07847.1"
                     /transl_table=11
                     /translation="MPPRPGVARTRRPPVPRRCGARKRSRRRPCVTAHNWEWSMKVGLL
                     FDARNPEGWQRPWADHYAQILELCEEAELHGADGVWFTEHHLFSDGYLPQPLTLAAAAA
                     ARTRRVRIGTSILQPALRVPAQLAEEAAVVDLISGGRLELGVGAGYRVPEYELFGANIN
                     TRFRRTEAHIVEMRRLWEERGVTPLPIQDPVPLWGGFYGPRGARMAGRLGIGLLHINPT
                     MFEHYRQGLAEGGHPPETARVGDLVPIILADDPDAAWPRVAPYLAHQMNSYRQASVEGT
                     DTPPPPLIRAEELRNRDPDGPWGMLEILTPQDAATRITELTRGLPVTQLIFWASVAGMP
                     DDLVVRNIELISHALPPLLREAAEVGADAPAGV"
     gene            11126..11914
                     /gene="hrbI"
     CDS             11126..11914
                     /codon_start=1
                     /gene="hrbI"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     131; E-value: 8.7e-40)"
                     /gene_functions="biosynthetic-additional (t2pks) KR (Score:
                     152.7; E-value: 3.4e-47)"
                     /gene_kind="biosynthetic-additional"
                     /product="putative reductase"
                     /protein_id="BAJ07848.1"
                     /transl_table=11
                     /translation="MPRGIHGQQPARQDSAGHRRQPGHRAGHRAAPGRGRSQWSTCNYA
                     TNESAAKETVALIEEAGGRAFAVRSQLGTQDSIQKLLSAVEAGLAEHTGGTTLDILVNN
                     AAATGFAGTAPEAVTEEILDHCYTLNAKVPFLLTQQALRLIPDGGRVVNISSGVTHAAF
                     PPQIAYAMGKGALEQITLHLAPVLAHRNITVNTVAAGITDTGDPVFSNPEAVEAMSAQS
                     AFKRVGTVSEVADIVAFVASGDARWMTGAFVDATGGTLLG"
     gene            11960..12640
                     /gene="hrbJ"
     CDS             11960..12640
                     /codon_start=1
                     /gene="hrbJ"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF07366"
                     /gene_kind="biosynthetic-additional"
                     /product="putative oxygenase"
                     /protein_id="BAJ07849.1"
                     /sec_met_domain="PF07366 (E-value: 2.7e-07, bitscore: 21.6,
                     seeds: 29, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNTTVSAVGFARPRPEVAEEFGAKLVALAAQARTEQGSIHTYIH
                     RDIAEENLFVFYETWESQTDVDRHLDQPYMKEFLTSLPDYLQEELKVHQLALVGPLSEP
                     AADPSDPAEMNQRYVDAYNARDIDGILAVYAPGAQSVWQPGQAVTAAEHRDTVVEFLKR
                     EPRLTADVRETYVVGDTAALVVDWSLEVPGAPELTGTGRGLDVLKRNAQGQWRYIITNP
                     FGSP"
     gene            12674..13300
                     /gene="hrbK"
     CDS             12674..13300
                     /codon_start=1
                     /gene="hrbK"
                     /product="putative oxygenase"
                     /protein_id="BAJ07850.1"
                     /transl_table=11
                     /translation="MGSIRVEDGYLSLFNIFHIEGAPGQDRLFETFRGLPPAKVQPGLV
                     SGNIHRGTDGRSVLNYAQWESQAAYDAFRAETATKGRLDQALTFSRMDSVATEVVHTWQ
                     PAPRLSVDDGLLTAVVLITTTPEHQAEVLKELVQDDPALADTPGFVSDAVHRGLSGEHV
                     VKYAQWEDEAAFRSYLGKQRSPSAVEYLISVEIHLSRLEYVRGRS"
     gene            13339..14415
                     /gene="hrbL"
     CDS             13339..14415
                     /codon_start=1
                     /gene="hrbL"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1191:acyl-CoA dehydrogenase type 2 (Score: 311.2;
                     E-value: 1.4e-94)"
                     /gene_kind="biosynthetic-additional"
                     /product="putative oxygenase"
                     /protein_id="BAJ07851.1"
                     /transl_table=11
                     /translation="MTAESAGRGAAEADASGRIGAETVEALTAAGFPSAFVPERWGGAD
                     ATCGAVAKAVAEIGAGCASAAWIASLLAYSGRFAAYLPTEGQEEVWAKGPRTRLVSSMV
                     ASGVRAEPTAGGWRLSGSWLYVSGVAFADWALVSSSPPREGDRNVRVFAVPRDVFTYED
                     TWEAIGMHATGSHTLTVADAFVPEYRAFVWDDMRQGILAGPATRAQSAPLFSVNGLTFA
                     APILGAARGAQIVAGQHLSVQPNGPRTAARESSLLSFARAATEIDAAELLLQRVADTAD
                     GGLLDDGLAVRSHRDATVAVQILMGAVDRLFGVTGTRGQARSHRMQRIWRDVHTAGSHA
                     ALQFEPAGLGYARRLLSA"
     gene            14523..14786
                     /gene="hrbM"
     CDS             14523..14786
                     /NRPS_PKS="Domain: ACP (13-82). E-value: 4e-10. Score:
                     31.8. Matches aSDomain: nrpspksdomains_hrbM_ACP.1"
                     /codon_start=1
                     /gene="hrbM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1129:acyl carrier protein (Score: 110.7; E-value:
                     4.5e-34)"
                     /gene_functions="biosynthetic-additional (t2pks) ACP
                     (Score: 125.5; E-value: 1.4e-39)"
                     /gene_kind="biosynthetic-additional"
                     /product="putative acyl carrier protein"
                     /protein_id="BAJ07852.1"
                     /sec_met_domain="PP-binding (E-value: 1.1e-08, bitscore:
                     26.7, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAREFTLDDLRRILVEAAGADESVNLDVDILDTDFESLNYESLA
                     LLETGGRIEREYGITLEDDALSIEHTPRKLIELVNAHLKTTG"
     aSDomain        14562..14768
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_hrbM_ACP.1"
                     /evalue="4.00E-10"
                     /label="hrbM_ACP.1"
                     /locus_tag="hrbM"
                     /protein_end="82"
                     /protein_start="13"
                     /score="31.8"
                     /tool="antismash"
                     /translation="ILVEAAGADESVNLDVDILDTDFESLNYESLALLETGGRIEREYG
                     ITLEDDALSIEHTPRKLIELVNAH"
     gene            14789..15697
                     /gene="hrbN"
     CDS             14789..15697
                     /codon_start=1
                     /gene="hrbN"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_kind="biosynthetic-additional"
                     /product="putative hydrolase"
                     /protein_id="BAJ07853.1"
                     /sec_met_domain="PF00561 (E-value: 1.7e-10, bitscore: 32.0,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 4.2e-13, bitscore:
                     41.5, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATSGEPRPAVGARVRRIRVSAGDLALSGLLGEPLDAPPRAVVV
                     ALHGAGMSAEYFHGRAHQDVSLATLGTLLGFSVLALDRPGYGASAADAPHGRTLDEQAA
                     AVHAAMAWFADRHAVGAGFFLLGHSYGGKVALTAAAQPAGEDLLGVDVSGCGQEYAVPD
                     GLLDDRRSEDWTKNWGALRCYPPSTFTLSKSVVSPVPKQERAEARRWPGRFAQVAAAVR
                     TPVRFTFAEHESWWRHDETAVGDLRARFTSSPRVLVERQPDSGHNISLGWSARSYHLKA
                     LGFLEECLASDARRRERALHH"
     gene            15732..16517
                     /gene="hrbO"
     CDS             15732..16517
                     /NRPS_PKS="Domain: PKS_KR (8-161). E-value: 2.1e-09. Score:
                     29.4. Matches aSDomain: nrpspksdomains_hrbO_PKS_KR.1"
                     /codon_start=1
                     /gene="hrbO"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     253.9; E-value: 2.6e-77)"
                     /gene_functions="biosynthetic-additional (t2pks) KR C9
                     (Score: 481.7; E-value: 1.1e-147)"
                     /gene_kind="biosynthetic-additional"
                     /product="putative ketoreductase"
                     /protein_id="BAJ07854.1"
                     /sec_met_domain="adh_short (E-value: 4.1e-39, bitscore:
                     125.5, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQQEKRSALVTGATSGIGLAIARLLGREGYRLYIGSRNADNVAS
                     TVKQLRDEGVEVDGSAVDVRSGTDVRAFVQAAVDAYGPVDVLVNNVGRSGGGVTADIED
                     ELWEDVIETNLTSVFRVTREVLNTGGMRGRDRGRIINIASTAGKQGVVLGAPYSASKHG
                     VVGFTKALGNELAPTGITVNAVCPGYVETPMAQRVRQGYADAYHTTEDAILEKFQAKIP
                     LGRYSTPEEVAGLVGYLASDTAASITSQALNVCGGLGNF"
     aSDomain        15756..16214
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_hrbO_PKS_KR.1"
                     /evalue="2.10E-09"
                     /label="hrbO_PKS_KR.1"
                     /locus_tag="hrbO"
                     /protein_end="161"
                     /protein_start="8"
                     /score="29.4"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="ALVTGATSGIGLAIARLLGREGYRLYIGSRNADNVASTVKQLRDE
                     GVEVDGSAVDVRSGTDVRAFVQAAVDAYGPVDVLVNNVGRSGGGVTADIEDELWEDVIE
                     TNLTSVFRVTREVLNTGGMRGRDRGRIINIASTAGKQGVVLGAPYSASK"
     CDS_motif       15759..15821
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_hrbO_0001"
                     /evalue="1.60E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="hrbO"
                     /protein_end="30"
                     /protein_start="9"
                     /score="17.5"
                     /tool="antismash"
                     /translation="LVTGATSGIGLAIARLLGREG"
     gene            16536..17471
                     /gene="hrbP"
     CDS             16536..17471
                     /NRPS_PKS="Domain: Polyketide_cyc2 (4-146). E-value:
                     5.8e-13. Score: 41.3. Matches aSDomain:
                     nrpspksdomains_hrbP_Polyketide_cyc2.1"
                     /codon_start=1
                     /gene="hrbP"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1128:cyclase/dehydrase (Score: 453.4; E-value:
                     6.3e-138)"
                     /gene_functions="biosynthetic-additional (t2pks) CYC C7-C12
                     (Score: 495.2; E-value: 1.3e-151)"
                     /gene_kind="biosynthetic-additional"
                     /product="putative aromatase"
                     /protein_id="BAJ07855.1"
                     /transl_table=11
                     /translation="MTTREVEHEIIADAPAEAVYRLIAEVENWPRIFPPTIHVEYLDRG
                     VDDERIHIWATANDEPKNWTSRRTLSPADLRIDFRQEVSTPPVAAMGGAWIIEPVTATR
                     SRIRLLHDYRAVDDTPENLKWIDEAVDRNSRAELAALRTNVERAHAEAELTFSFEDSVA
                     VDGAVKDAYDFINEAYLWSERLPHVAKVRLSEDTPGLQSLEMDTQAQDGSVHTTKSYRV
                     TFPHHKIAYKQVTLPALMNLHTGYWTFTESDSGVTASSQHTVVLNTANIARILGDDATV
                     ADAREYVRNALSTNSRATLGHAKAYAEGRR"
     aSDomain        16548..16973
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_hrbP_Polyketide_cyc2.1"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="5.80E-13"
                     /label="hrbP_Polyketide_cyc2.1"
                     /locus_tag="hrbP"
                     /protein_end="146"
                     /protein_start="4"
                     /score="41.3"
                     /tool="antismash"
                     /translation="EVEHEIIADAPAEAVYRLIAEVENWPRIFPPTIHVEYLDRGVDDE
                     RIHIWATANDEPKNWTSRRTLSPADLRIDFRQEVSTPPVAAMGGAWIIEPVTATRSRIR
                     LLHDYRAVDDTPENLKWIDEAVDRNSRAELAALRTNVE"
     gene            17501..18340
                     /gene="hrbQ"
     CDS             17501..18340
                     /NRPS_PKS="Domain: ACPS (125-188). E-value: 6.6e-09. Score:
                     27.5. Matches aSDomain: nrpspksdomains_hrbQ_ACPS.1"
                     /codon_start=1
                     /gene="hrbQ"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1012:4'-phosphopantetheinyl transferase (Score: 137.8;
                     E-value: 5.5e-42)"
                     /gene_kind="biosynthetic-additional"
                     /product="putative phosphopantetheinyl transferase"
                     /protein_id="BAJ07856.1"
                     /transl_table=11
                     /translation="MRPSDPLGPDEPADLSLWLVRPPRPGTPAASRLAVDELDASENGR
                     ADLFVHPRDRLQYLAAHIALRRVLAARTGCPPGALRLGREPGPPGTNFSGRPVLVDPPA
                     PVHFSLSHSHGLILIGAASVVVGVDVQRVPTLQTVQLCGPSLHPAEWSELAKRPAARQP
                     AAFGRLWARKEAYLKGLGTGLRRSPALDYVGDAADVCAPPKPFGWIVRDVPVGPQYTAA
                     AALAVATEPTITLRSLPVSCLYGGNAGQPLSAAPLLAWRRKGSWTLRWSSWGRALQA"
     aSDomain        17876..18064
                     /aSDomain="ACPS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_hrbQ_ACPS.1"
                     /evalue="6.60E-09"
                     /label="hrbQ_ACPS.1"
                     /locus_tag="hrbQ"
                     /protein_end="188"
                     /protein_start="125"
                     /score="27.5"
                     /tool="antismash"
                     /translation="VGVDVQRVPTLQTVQLCGPSLHPAEWSELAKRPAARQPAAFGRLW
                     ARKEAYLKGLGTGLRRSP"
     gene            18376..19758
                     /gene="hrbR"
     CDS             18376..19758
                     /codon_start=1
                     /gene="hrbR"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050:monooxygenase FAD-binding (Score: 509; E-value:
                     2.6e-154)"
                     /gene_functions="biosynthetic-additional (t2pks) OXY
                     (Score: 535.6; E-value: 2.8e-163)"
                     /gene_kind="biosynthetic-additional"
                     /product="putative oxygenase"
                     /protein_id="BAJ07857.1"
                     /transl_table=11
                     /translation="MTVLERLEQRTGESRGIGFTIRTMEVFDQRGVLRRLGPIETATAG
                     HFGGLPLDLGVLGAAHRAARTVPQSVTEQALEGWARELGADIRRGQEVQALEDTGDGVT
                     VTVARGDNREILRARYLVGCDGGRSTVRKLAGFDFPGTDATTEMLLADVRGVELEPRMS
                     GQQIGNGFLMVAKLPGGIHRLIVGERGIAPRRRTGPPPFSEVADLWKRLTGSDISHAEP
                     VWVSAFGDAARQVTEYRRGRVLLAGDAAHVHLPAGGQGMNTSIQDSHNLGWKLASVLAG
                     HAPEALLDTYHSERHEVGRRLLVNTRAQSQLILGGEEAQPLREALSELLQYPNVVRHLA
                     AKASGLDIRYDVGGGTNPLLGRRLPHLPLTTGARRTSSTELLRAGRGVLLDLGDNARLR
                     DRATPWRNRVDVVTGTADPEHALPGGTTAALVRPDGHVAWAAPGSHQDLATSLTRWFGP
                     AT"
     gene            19901..20665
                     /gene="hrbS"
     CDS             19901..20665
                     /NRPS_PKS="Domain: PKS_KR (7-149). E-value: 6.7e-10. Score:
                     31.0. Matches aSDomain: nrpspksdomains_hrbS_PKS_KR.1"
                     /codon_start=1
                     /gene="hrbS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     183.4; E-value: 8.7e-56)"
                     /gene_functions="biosynthetic-additional (t2pks) KR (Score:
                     127.5; E-value: 1.6e-39)"
                     /gene_kind="biosynthetic-additional"
                     /product="putative ketoacyl reductase"
                     /protein_id="BAJ07858.1"
                     /transl_table=11
                     /translation="MTAESVPVAVVTGANKGIGREIARQLAVRGLVVYLGARSERRGRE
                     AESALRADGLDIRFLHLDVTDETSVALAAKRLEDEVGVVHALVNNAGVGGPYLPPSRTS
                     AAQVRETYDTNVFGVITVTNALLPLLRRAGSARIVNVSSAVGSLSAAAANVDPTGVHLP
                     GEFPTLLAYNTAKAALNSVTVTYANELRGTGILVNAASPGFVATDINGHHGILTPEQGA
                     HIPVLLATLGEDGPTATFLGENGTPEGQVLDW"
     aSDomain        19922..20347
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_hrbS_PKS_KR.1"
                     /evalue="6.70E-10"
                     /label="hrbS_PKS_KR.1"
                     /locus_tag="hrbS"
                     /protein_end="149"
                     /protein_start="7"
                     /score="31.0"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VAVVTGANKGIGREIARQLAVRGLVVYLGARSERRGREAESALRA
                     DGLDIRFLHLDVTDETSVALAAKRLEDEVGVVHALVNNAGVGGPYLPPSRTSAAQVRET
                     YDTNVFGVITVTNALLPLLRRAGSARIVNVSSAVGSLS"
     CDS_motif       19928..19990
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_hrbS_0001"
                     /evalue="7.80E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="hrbS"
                     /protein_end="30"
                     /protein_start="9"
                     /score="18.5"
                     /tool="antismash"
                     /translation="VVTGANKGIGREIARQLAVRG"
     gene            20662..21966
                     /gene="hrbT"
     CDS             20662..21966
                     /codon_start=1
                     /gene="hrbT"
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 137.6; E-value:
                     6.8e-42)"
                     /gene_kind="transport"
                     /product="putative transporter"
                     /protein_id="BAJ07859.1"
                     /transl_table=11
                     /translation="MTGSRPAPAGRPVVRERWDARRRILLAVLSGNMLLDAVEVSVVLI
                     ALPTIADRLGLSPLAAQWLMSGFALGFAVLLPLGPVLAGRVGRRPVYLGAMLLFGLASV
                     VGGLVDGLAVLVVIRLLKGACAALTAPMGLAIISDVFPDGPQRRRALAVYSLFGAGGFT
                     SGLLLGGVLLEAGWRWVFVFPAPVALVLFLGGMRVLPGTHSGARPGLPRPALLREGSLL
                     RSALGAAILNGTYQSLLLVMVFQSMGGFGWAPWFTALALLPACLPLAVTIPFAGRLIAR
                     YGGGRLITLGALFPLLGYGLYLARPEGSPYALGMLPALLLVEAGFCCSFVALNMRATAS
                     LAPADRGAAVSLYQMCVQLGAAVLLPLVALLLTHGDGPRPALTLITAAGALGLLVPLAV
                     HRVSARSDPGPDPRAPDGPAPHPSRTPPQGDLPHG"
     gene            21986..22990
                     /gene="hrbU"
     CDS             21986..22990
                     /codon_start=1
                     /gene="hrbU"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:O-methyltransferase (Score: 233.2; E-value:
                     7.9e-71)"
                     /gene_functions="biosynthetic-additional (t2pks) MET
                     (Score: 288.3; E-value: 1.8e-88)"
                     /gene_kind="biosynthetic-additional"
                     /product="putative O-methyltransferase"
                     /protein_id="BAJ07860.1"
                     /transl_table=11
                     /translation="MHPGPIMGLMAGYWQVRMLLAALEHDIFTELSKGPATSGEVADRM
                     GLVELGTHDLLTGLGHLGLLQVADGRFANSPLADRFLVRGGPEFLGGYLRFCEQELNPA
                     WDGLATSLRTGRPTNRAAVVGNPYDTLYSDPDATDGFLDSMDLLSTPIGLAISRYDWSQ
                     YSSFIDVGGARGNFAHQVVTENPHLTAGVFDLPPLEGTFKRHIERLGATASGISFHGGD
                     FFKDKLPKADVIVLGHVLHNWGVEDRVQLLKNVYDAVRPGGAVFVYDPMAGGEQPSLHA
                     VLAGLAMLVWSRGGHEYSVEELHGWLREAGFWPETAEVPGLHEDVLVIGHKDA"
     misc_feature    22736..22738
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            23212..24003
                     /gene="hrbV"
     CDS             23212..24003
                     /codon_start=1
                     /gene="hrbV"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     161.4; E-value: 4.4e-49)"
                     /gene_functions="biosynthetic-additional (t2pks) KR (Score:
                     110.0; E-value: 3.5e-34)"
                     /gene_kind="biosynthetic-additional"
                     /product="putative short-chain dehydrogenase/reductase"
                     /protein_id="BAJ07861.1"
                     /transl_table=11
                     /translation="MKIENSVGVVTGAASGIGKAIAVALVEAGARGVVVSDIDGEGAEK
                     VAASIGDAAIAVRADVTDEAAVRALVARARERFGTIDLFVSNAGLPVTGGYETSDEDWK
                     RALDVNLMAHVYAARAVLPTMLATGRGHLLQTIAACGVLTAFGAAAYSVAKQGAVAFAE
                     YIAIEHGGQGIGVSCLLPQAVDTPMLAAGVKSSEQLALLKAHSEVLEPGQVAAAALQGV
                     EENRIHIHTHTGSAESFRLRAQDPDRWVAEMRAIRSGRPAA"
     gene            24125..24706
                     /gene="hrbW"
     CDS             24125..24706
                     /codon_start=1
                     /gene="hrbW"
                     /gene_functions="biosynthetic-additional (t2pks) KR (Score:
                     43.4; E-value: 7.3e-14)"
                     /gene_kind="biosynthetic-additional"
                     /product="putative reductase"
                     /protein_id="BAJ07862.1"
                     /transl_table=11
                     /translation="MDEEKLRLVVIIGSAREGRTGPAVARWFVEETRSSGLFDVDVIDL
                     GDVELPLTLTRVPGAEFTRVLADLGARLESADAFVVITPEYNHSFTAPLKNLIDWHRTQ
                     WQAKPVGFVSYGGLSGGLRAVEQLRQVFAELHAATIRDTVSFHQVWERIGEDGRLSSSD
                     ATIPAKVILEKLQWWAAALRDARVLRPYSA"
     gene            24769..25902
                     /gene="hrbX"
     CDS             24769..25902
                     /codon_start=1
                     /gene="hrbX"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1191:acyl-CoA dehydrogenase type 2 (Score: 228.3;
                     E-value: 2.1e-69)"
                     /gene_functions="biosynthetic-additional (t2pks) OXY
                     (Score: 17.0; E-value: 5.5e-06)"
                     /gene_kind="biosynthetic-additional"
                     /product="putative oxygenase"
                     /protein_id="BAJ07863.1"
                     /transl_table=11
                     /translation="MCGHRAPWPDAGLIRAAAATAGRHALHADVSGSLSPETVAALAAA
                     GFPGCFVPEPLGGAGATFGAATRAVAAIGEECAAAAWTASVWAYSGRGGAFLPAEGRAE
                     IWAKNPQARLVSSTAACGVRAAPVAGGWLLSGAWRCAGGAESADWALLSSAVPRTGDRS
                     VLMFAVARGSFTLAHCGESSMLGIRAAGRQTLVVERAFVPEHRAFVWDDMRRGRPAGPA
                     TTARLAPLSAVTGLAFATPILGAARGALRLAEERLAVRPRRSAARSSVRMPGRVAFARS
                     AAEIDAAALLLFRVAEDADMCRSDDTPTARGRRDSALAAELLTAAVDRLFRSAGSQGRA
                     SSHAMQRIWRDVHAAGAYNALRFESATIGDARGLLSV"
     gene            complement(25943..26545)
                     /gene="hrbR2"
     CDS             complement(25943..26545)
                     /codon_start=1
                     /gene="hrbR2"
                     /gene_functions="regulatory (smcogs) SMCOG1135:MarR family
                     transcriptional regulator (Score: 86.6; E-value: 1.9e-26)"
                     /gene_kind="regulatory"
                     /product="putative transcriptional regulator"
                     /protein_id="BAJ07864.1"
                     /transl_table=11
                     /translation="MTRTGYALAKRCNRTACIRKWFMVRTLWPIRYAVGVAKHDEGQMG
                     IVSALVRSSFLVDSVYARAAREYGLTSQQGQLLCVLMGQPYGMGELSSVLGLAKSSLSG
                     LVDRTESNGLVRREADPQDSRAVRVALTGRGARLADRFYTDACRRIQELSTGLGDDERD
                     TLAHLLGRLVLDNKVPVVFVGDRTDATQDGSELDTTA"
     misc_feature    complement(26465..26467)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            26627..27724
                     /gene="hrbY"
     CDS             26627..27724
                     /codon_start=1
                     /gene="hrbY"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175:pyridine nucleotide-disulfide oxidoreductase
                     (Score: 104.1; E-value: 1.1e-31)"
                     /gene_functions="biosynthetic-additional (t2pks) DIMER
                     (Score: 404.0; E-value: 7.8e-124)"
                     /gene_kind="biosynthetic-additional"
                     /product="putative oxidoreductase"
                     /protein_id="BAJ07865.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 3.5e-38, bitscore:
                     122.6, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSATVAVVGGGYGGAAVAKALEAEADVILIDPRDAFVNAAASLRA
                     LTQPDWAGNVFYPFDTLLTQGKVIRGRAASVDPRGVTLESGERVDADYVVLATGSNYAY
                     PAKPVSDTVSAALEDFRRTHKEVLDADRVLILGAGPVGLELAGEIKEVWPDKQVAIVDP
                     IAELLPGFKPEVVADLHQQLEELGIELRLGTSLKALPSTEPNRTGTFKVTTDAGDEITA
                     DIWFRAFGVDINSGYLTDGRLTTLTPQGQVPVTEKLNVDGYEHVYAVGDITDVAETKMA
                     GYAMQHAEVVAKNILAQIKGEQPEAVYQPLPHPMILLPLGPSGGVGQLPSAEGPFAAPR
                     TVVSEYKGSDLFTGRFIGQFGPTAG"
     misc_feature    26753..26755
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(27827..28549)
                     /gene="hrbR3"
     CDS             complement(27827..28549)
                     /codon_start=1
                     /gene="hrbR3"
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 195; E-value: 2.1e-59)"
                     /gene_kind="regulatory"
                     /product="putative repressor-response regulator"
                     /protein_id="BAJ07866.1"
                     /transl_table=11
                     /translation="MADHSAINPNAAGERDLPVRPSGWRVLVVESDSGDARVLTQGLRR
                     HGHDVSLAKDGREALDAFGDAELVLIDLDLPDLDGLEVCRSIRAVCDTPLIVVTGRESE
                     LDRVLGLQAGADDYLVKPYGFRELMARIEAVMRRITPRNTSADVVAHGRLRIDITSRQV
                     TLDGKDVQLTPKEFQLLHLLASQPGSVIPRQQIMVRIWGGSWSVRTLDTHVSSLRSKLG
                     ASESIITVRGVGFRLGHV"
     misc_feature    complement(28499..28501)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(29339..30253)
                     /gene="hrbZ1"
     CDS             complement(29339..30253)
                     /codon_start=1
                     /gene="hrbZ1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083:oxidoreductase (Score: 154.2; E-value: 8.4e-47)"
                     /gene_kind="biosynthetic-additional"
                     /product="putative N5,N10- methylenetetrahydromethanopterin
                     reductase"
                     /protein_id="BAJ07867.1"
                     /transl_table=11
                     /translation="MAQQVVFGFGAHSTIDTGPELLRLTRQADRDGLDLFSLSDHPYVG
                     ERLDAYAALGFIIGRTERLAGFANVSNLPTRPPAMLARAVTTLSALSVGRVVLGLGVGG
                     LWDRIADLGVPPLTAGQAVDAFEEAIVLVKKLSGGGPPVTFEGVHYRVNRIDPAPVAAP
                     PVWTGSVGPKSLAVTGRVADGWIPGHAADWLSERYRTSRPIIDQAATAAGRDPLDIRTV
                     YNLPGQITTRPTSSTRDRDGRWLGGSVDQWIEELTGAVLEHGASGFMLFSPQGGTADLA
                     SLQRWGGEIVPAVRAAIAKERDH"
     gene            complement(30360..31364)
                     /gene="hrbZ2"
     CDS             complement(30360..31364)
                     /codon_start=1
                     /gene="hrbZ2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039:aldo/keto reductase family oxidoreductase (Score:
                     317; E-value: 2e-96)"
                     /gene_functions="biosynthetic-additional (t2pks) KR (Score:
                     38.2; E-value: 2.9e-12)"
                     /gene_kind="biosynthetic-additional"
                     /product="putative aldo/keto reductase"
                     /protein_id="BAJ07868.1"
                     /transl_table=11
                     /translation="MEYTHLGRSGLSVSRLVLGTMNFGTETSEEDSHRIMDRAHEHGIN
                     FFDTANVYGSRGGTDLTESIIGRWFAAGGGRRERTVLATKVYIPTGEWPNERFLSALNI
                     RRAADASLKRLGTDHIDLYQMHHVDRSTPWDEIWEAFQVLRQQGKVLYFGSSNFAGWHI
                     ALAQEAARSRHFLGLVSDQSVYNLMNRWIELEVLPAARHFGLGVIPWSPLNGGVLGGVL
                     RKAKEGGALRGNTGRSIATLAGHRETVEAYEKLSADIGEDPAHVGLAWLLAQDGVTGPI
                     IGPRTVGQLESSLRALDIALDEVVLTALDRLFPAPGLNPVVNGPRPAPEAYAW"
     CDS             33303..33464
                     /codon_start=1
                     /note="orf2"
                     /product="putative truncated S-adenosylmethionine synthase"
                     /protein_id="BAJ07869.1"
                     /transl_table=11
                     /translation="MAGLRNLSLGDATTRSPTYLRSDAACGHFVREPPDFTWQRTDRVE
                     ALRTAAGL"
     CDS             33521..34531
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1276:PfkB domain protein (Score: 67; E-value:
                     2.9e-20)"
                     /gene_kind="biosynthetic-additional"
                     /note="orf3"
                     /product="putative carbohydrate kinase"
                     /protein_id="BAJ07870.1"
                     /transl_table=11
                     /translation="MRIAVTGSIATDHLMTFPGRFAEQLLPEQLDSVSLSFLADTLEVR
                     RGGTGANIAYGLALLGRSPVLVGAVGPDFAADRERLEALGVDTSHLWVSAHHQTARFVS
                     TTDLDQNQIATFYPGAMAEAGKIDLRRIAASGGGLDLVLIAPDDPKAMVRHTTVCVQTR
                     LPFAADPSQQLARLDRQEARALLAGPRYLFTNEYEASLLLERTGWSEREVLDRVGTWVT
                     TLGAAGVRLRAAGRPDVLVSALPSTAVAEPPVCVGDAFRAGFLAALAGGADEETAARHG
                     CALAVIALESVGGQEYHAGPAELRRRVFQGYGEVISGRDEPVREPSHKQKRVPGR"
ORIGIN
        1 tgggcgagct ggtgcagcgc gcctcgcagc agttgaccga gctggtgcgc ggcgagatga
       61 agctggcgca ggcggagatg aaggagaagg gcaagcgcta cggcaagggc ggtggcctgt
      121 tcggcggggc tggcgtcgtg ggcttcctga tgctgcaggc gctgatcgcc accgcgatcg
      181 ccgcgctggc ggtgccgctg ccggtgtggg cagcggcgct gatcgtcacc gcggtgctgg
      241 gtgtgatcgc cgcgatcatg gccatgagtg gaaagaagca ggtcgaccag gccgcgccgg
      301 ccgcacctga gcagatgatc gagaacgtga aagccgatgt gaccgagatc aaggagagtt
      361 cccaccgatg acccagccgc ctcacgacga gcccaccgcc tccagccccg acgagctgcg
      421 cgagcaggtc gagcagaccc gcgaagagct cgggcagacg gtcgaggcgc tcgcagccaa
      481 gaccgacgtc caggcgcgcg cccaggagaa ggccgccgag gtcaaggagc aggccaccgc
      541 caaggccggc gagctgaagg agcaggccac ggtcaaggcc ggggagctga aggcgaaggc
      601 caccgacctg gcgcaccagg tgcaggacag gctgcccgac ccggtcaagg acaaagccgc
      661 ccaggccgcg gggcaggccc gaacgaaggc agcccaggcc gggcaggtgt gggaggagaa
      721 ggcgcccgag ccgctgcggc agaagacggc ccaaggggcg cagctggcgc gggacaaccg
      781 caaggtgctg ctggcggccg cgggcgtggc cgtcgtggtc tggcttgcct gccgtcgccg
      841 gaaggggtga gccaggggga aaggatccaa gatcgcctat taagccggtc ggtctggcgc
      901 tcggggccgt aagcggaatg gccgcgggaa cgctgttcaa gcaggcgtgg aagatgctgg
      961 gccacgatga cgacgccccg gacgccaccg acgaagaacg ctcctggcgc gaggtgctgc
     1021 tcgccgccac gctgcaaggg gcgatcttcg ccggagtcaa agccgccgtc gaccgggccg
     1081 gcgccaccgc cacccgccgc ctgaccggca cctggcccgg ttgacgcatg aggatgagga
     1141 ggcgccggta cgacacggat gccgggcctc ccatcgcccc cggcacatac ccgtacgaag
     1201 gacgtcacag ccatgtccga tcagcatgcg gctgccgcgc tgaccgccgc cgcagtcatc
     1261 gccacgatcc tgatcgcccg ggcagcggtc ctccaccaca gcggccgagg acacgccgcc
     1321 agcgctgccc acacgcgccg ccgcagcaca cccccgccga gaaagccgca ccatctccag
     1381 tcacgccctt tgacgacgcc tccagcgccg tgcgcgaggc tgagcagcac gtccaccgct
     1441 gtcggcagca gctccacacc cgtgccgatc cgcccgagtg acctgcccgc gggcgcagcc
     1501 ggcaatccgg cgtgagcgcg ggcgaatcga gtgcttcgcc aaccatcgcc gcgtaccggc
     1561 tggggcgacc ctggcggccg gcaaggtctc cgcctggccg gctccagggc tgtgcgtgct
     1621 cttgcttgac agacaagccg ggacgctggg gaccacagat gcgcccgctt cgccgaaccc
     1681 gtccgcatcc gccgacccga ggaacccgct aatccgacgt ccggcagcag gccgtcttgc
     1741 agcgggcgtc ctcggacatg aagcagctga ccgtcgcgcc caggagacgt gcgtacttca
     1801 ggccgctccc cttctcaccg tcgttggcgg cctcgctgag ctggacgtcc gggcgcgggt
     1861 cttgcacgtc gatcagcagc gcctcgtccc cggtcacggc caggcgtatg gtcatccgcg
     1921 ccggttcctc gtcggcgagc tgttgggcgc tcccggagcc ctggccgcgc cggaacagag
     1981 agctgtccgt ccgcgagatc tgcgccgtac cggaggccga gggtacccgg ccgaagcgtt
     2041 gctacggccg aggccggcga acaggtgcag tacatggtgc gacggatcga ccagaccctc
     2101 ggcgagcccc gcgtcctgga gtaccaccgc cgcctgcggg gggctcgcca ggtgttcggg
     2161 gcatggcgcg gcgcgctcac cgccggtgtc ttcgctggtg tcatggtctg tcgcggacga
     2221 ggaaagctgg actgcacgtc tcgtcggcag gcccggtccc catcgtcccc gtcgggtgtt
     2281 ctgagctcgc tctgcatgag ctctgacgtt cgcctgacta aatccgaaga caggtgtgat
     2341 tttcctgtcg aactggacct gactttgacg cttcttctct tgatgtcgag tcgtcgtccg
     2401 aagaatattg atgtcagggt ccggagctct gtggccaatg ccctccgtga ctgccgaatc
     2461 gctgggtgcc gacgcaccga agaagccact gcacaggaaa gaccacgggt ccgatcggac
     2521 cccgctaccg gcgcgtcaga agagattggg aaaacgatgc cgtcgagcag ttacgaagca
     2581 aaccagtgcg acagtcaccg ttgccgtaga gcggctcttg acggcggtgg gcgacggcct
     2641 gccgcccgag gccgtttatg ccgtgagtgc ttcagcctgc tttcagcggg aattcgagat
     2701 ctgccgcggc tgtacgcgga gtgcgaggag gctctcagcg gcggagccgc ggcgggagtt
     2761 cgcgagaaga cgagcggcgg gtcgccgtcg cgggggctgg tgttcaacgg cttcgcggcc
     2821 gaggccagga cccgcatcgt caccacgctc gggtcgtggt gcggcctggt cgcggatcag
     2881 cgcgcggtgc ccccgccggt ccggcaggtc ggtgcgctgg cgaacttcct gctgacccac
     2941 ctcacttggc tcgccaccca cccggcggcg ggcgaactca ccgcggaggt cgcgcgggcc
     3001 gcgggcttcg cgcgccgtgc cgccgacccc agctccgtgc agcggttcac ggtcggaccg
     3061 tgtgtggtgc gggagtgcga cggtgcactc tcggcgacca tacgcggcgg ccgggccggc
     3121 ggcacgcagg tgcagtgcac cgtgcacccc gaccaccggt ggggtgagca cgagtgggca
     3181 cagctgcgcc gggagaccct acgcagctca ccgcccaccg gcgagcactg gttgaccgcg
     3241 ccggacatcg cccgactgtg gaacacgccg accgggacgg tctaccggct cgccagcgag
     3301 cacaagtggc gccgcatctc ccgctcaggg cgcacgtact acgcggaaaa cgacgtggcc
     3361 gcgagcctca gccggcgcaa ggagcgggcc gtccgacggt gacaagccgg agggacgacg
     3421 gccgggtccg ccatcgccgt gtgcttcgcg gtgaatttcc cgcgcgggcc ttcccggtcg
     3481 gctattccgc tcagcgcttg cctcggcatc cctccccctc cgacctttcc cgctccggcc
     3541 tttcaacccc catcctccct gcccaaaagg ggtttttacg ccgcagaaca gtggccattt
     3601 cccgctcgac cgacaacgga acgacgtgga ggagacacga atgcacagca ccctgatcgt
     3661 ggcacgcatg aatcccaaag aattcggcca tgttgccgat ctgtttcgta aattcgacga
     3721 aacggagatg ccacacctga tgggcacccg ccgacgtcag ctcttccact accaggggct
     3781 ctacttccac ctgcaggact tcgactactt gggatcaacg gcggaccgag cacgaatcca
     3841 gcgagcgcgg aaagacccgc gtttcatccg gatcagcgac gacctgaagc cgtatatcca
     3901 ggcatacgac ccggccacct ggcggtctcc ggccgacgcc atggcgacgc ggttctacca
     3961 gtgggttggc gcgtcgtgaa tggtcgtcgc gcggtcatca caggcctgga ggtcctggcc
     4021 ccgggtggcg tcggcgccaa ggacttctgg tcgctgctga gcgaggggcg taccgcgacg
     4081 cggggcatca ctttcttcga cccggcgccg ttccgctccc gggtggcggc cgagatcgac
     4141 ttcgccccag aggcacatgg cctccatccg caggagatcc ggcgaatgga ccgtgccgcg
     4201 cagttcgcgg tcgtcaccgc gcgcggtgcg ctgcgtgaca gcggcttgga gttggagggc
     4261 tacgccccgc accgggtcgg cgtgacggtg ggcacggcgg tcggcgcgac gatgggcctg
     4321 gacgaggagt accgggtggt cagcgacggc ggccggctgg acctcgtcga ccacacctac
     4381 gcggtgccgc acctgtacaa ctacctggtg cccagctcct tcgcggccga ggtggcctgg
     4441 gcggtgtcgg ccgaggggcc gaactcggtg gtgtcgaccg ggtgcacctc tggcatcgac
     4501 gcggtgggct acgcagtcga gttgatccgc gagggatcgg cggacgtgat ggtcgccggc
     4561 gcctcggacg cgccgatctc tccgatcacc atggcgtgct tcgacgcgat caaggcgacc
     4621 acgccgcggc acgacgaacc gcagaaggcc tcccgcccgt tcgacggcac ccgcaacggg
     4681 ttcgtgctcg gggagggggc ggcgttcttc gtgctggagg agttggagtc cgcccggcgg
     4741 cgcaacgcac acatctacgc cgagatcgcc gggtacgcca cgcgcagcaa cgcctaccac
     4801 atgaccgggc tgcgtccgga cggagcggag atggccgagg cgatccggtc cgcgctggac
     4861 gaggcgcgga tgaaccccga ggagatcgac tacatcaacg cacacggctc gggcaccaag
     4921 cagaacgacc ggcacgagac ggcggcgttc aagaagagcc tgggcagcca cgcccgcgcc
     4981 acaccggtca gctcgatcaa gtcgatggtg ggccactcgc tgggcgccat cggctccatc
     5041 gagatcgccg cctcgaccct ggccatggcg tacaacctgg tgccgccgac ggcgaacctt
     5101 cacacgcccg accccgagtg cgacctggac tacgtgccgc tgaccgcccg ggaacaccgg
     5161 accgacacgg tactgaccgt gggcagcggc ttcggcggct tccagagcgc gatggtgctg
     5221 gcccgccccg aaaggaatgc cgcatgagtt caccgagtca acctcgatcc ggccgagggc
     5281 gtgtcggcgg tcctgttgat cctgcggttg gccggggggt ggcgactgtc gccggtgcgg
     5341 gcgtcgttgc agatctcggc ggcacggtcg ccggtgggcc ggctgtcgtc ggcgatggcc
     5401 tggctgagta cggcctcgat gacgtcgggg cgcatcggca ccaccgggcg accggccgcg
     5461 gtcgtggtga agcccctctc ggcgtgggcg aactcccaca actggacacg ctcgccggac
     5521 tcgtccacgc catgctcacc tggccgtgcc cccaccggga ccaagaggtc acaaccccac
     5581 cgaagagggc tgcggaagaa atgaacctca catgagcgtc tcggcggtgg tgaccggcct
     5641 cggtgtggtc gcccccaacg gactcggagc ccaggagtac tgggcggccg cacgggtcgg
     5701 cacgagcgcg ataggccgga tctcccgctt cgacccgacc cagtacccct ctcggctggc
     5761 cggcgagatc cacggcttcg tggccgagga ccacctgccc aaccggctgc tgccgcagac
     5821 cgaccggatg acccggctcg cgctggtggc ggcggactgg gcgctggagg acgccggcat
     5881 cgacccgcgg gaactgcccg cgttcgacat gggcgttgtc acctccagcg cctccggcgg
     5941 cttcgagttc ggccagggcg agctgcaacg gctgtggagc cagggcagcg agtacgtgag
     6001 cgcgtaccag tccttcgcct ggttctacgc ggtcaacagc ggccagatct ccatccgcca
     6061 caacatgcgc ggccccagcg gcgtggtcgt cagcgaccag gcgggcggac tggacgcggt
     6121 cgcacaggcg cggcggcaga tccgcagggg cacgccactg atcgtctccg gtggggtgga
     6181 cgcctcgttg tgcccgtggg gctgggtggc ccaactgacc agcggcctgc tgagcagcga
     6241 cgacgacccg gccacggcgt acctgccgtt cgatcgcagg gcctccgggc acgtgccggg
     6301 cgagggcggc gccatcctca tcgtggagcg ccgggacctg gccgcggcgc gcggcgcgcg
     6361 cgtctacggc gagatcgccg gctacggcgc caccttcgac ccgcgtccgg gcagcgaccg
     6421 tccgccggcg ctgcgcgcgg cgatcgaggc cgcgttggcc gacgccggcg cggatgccgc
     6481 cgacgtggac gtggtcttcg ccaacggcgc ggccatgccg gaactggacc gggtggaggc
     6541 cgatgcgatc aacgcggtct tcggtgcccg gcaggtgccg gtcaccgtgc ccaagacggc
     6601 aacgggctcg ctgtactccg gtgctgccgc gctcgacctg gcgacggtct tcctcgccat
     6661 cgaggagggc ctgatcccgc cgacggtgaa caccgagccc gacgaaggtt acggcctgga
     6721 cctcgtggtc ggccgtccgc gcaccgccga gatccgtacg gccctcgtcc tggcgcgcgg
     6781 tcaccggggc ttcaactcgg cgatggtcgt gcgctccgct gactgatccg actgatcgaa
     6841 ccgacgacac cgggagtgaa agacgatgcc tgtagcctcc gacgccccac cggacttcgg
     6901 ccgttccgac gtcgaggcgg tggtggtcac caccgcctcg ctgccgaaac cgaacgccgc
     6961 ggagctcgcc gacaccgtgg ccgcgcgctg gcaggccggt ccgtggccgg ccgagcaggt
     7021 ggcgctgagc gtgttcatcg gcggagatgg cacctcggtg ctgacctacg cgcagtggtc
     7081 ctcgcgcggc gcgctggagg agtcgctgag ggaccacggg agcgtgtcgt gggcgaacgc
     7141 cccgggcgcg ctgctgggcg agggcgccga cagcggggtg cggaccaccg ggccgctgcc
     7201 gttcgggatc tatcgcacgg tgcgcggcac cgcggtcacc gaggagaacc cggtgccggt
     7261 gagtttcccg gtggcgttct tcacgatggc cgacgaggcg tcggcggcgg cgtgggtgga
     7321 cggcctgctg tcggcggagg aggagaacga gggtgacgag cgcgcctacc cggacgccat
     7381 cgcagccaac ttccacgtca gcctggacgg cacccaggtg ctggtgctgt cggagtggct
     7441 ctccgcggag gctgcctcgc agcacatcgc cgacgtgtgg gacccgatcc tggcgcactt
     7501 cggcggcgac gccggcgcgc tgtaccggca ccacacgacg ctcaacgcgc tggagaagac
     7561 agccgactga cggtgccgcg cgcaggtcgg ccccagaagg aaggcctgcc cgcgacccga
     7621 ccaccccgat cggctgtgcc gcgacgtcgc gtgcccgcgt ccaaggagtg cacccagtca
     7681 tcatggctac tcgtcaccga atcctggcta ctcgccaccg cagcggtcgg cccgtgcgcg
     7741 gcgcgccgcg gctcccgcca tcacggtggg cgcggctggc ccgtccaagg tcccgtcgcc
     7801 ggccggccgc ccaccgggcc gctcccgcca cggcatcccc cgaagcgggg tgctgacccg
     7861 atgagcgggc cggagagggg cggcgcgcac gccggcgggg gcccggtcga gccatattca
     7921 cacgcgctgg aacctgacgt gctgatcgtc ggtgccggtc cggccgggct gttgctggcc
     7981 ggcgacctgg cgtccgacgg ggtgcgggtg acggtggtgg atgcgctcac cgagccgatg
     8041 accgagtcac gtgcctcgac cttgcacgcg cgcaccatgg aggtgctggc cgcgagggac
     8101 ctgttggagc ggctgggccc gccgccgccc ggtggtcccg gccacttcgg cggcctgcgg
     8161 ctggacctgg ccgaggccga tccgcagcac cggcacgccg ggcagtggaa gtgcccgcag
     8221 acgctactgg agcgtgaact cgctcggtgg tcaaccgagt cgggggcact gctgctgcgc
     8281 gggcaccggc tcgtcgcgct gacccagacc gcccaccggg tggaggtcga gttgaagtcg
     8341 gccgacggct cccgggtcgc ggcacgggcg ccctaccttg tcgggtgcga cggcgaacgc
     8401 agcaccgtac gggagctggc cggcttcact ctggccggcc ggagcgccgg gcgggagatg
     8461 ctgcgggccg acgtcgccgg catcgacgtg cctgaccgcc gcttcgagcg tctgccccgg
     8521 ggcatggcga cagcggcccg gtggccggac ggctcgactc ggctgatggt gcacctgtac
     8581 ggccaccggc cgcagccgcg ctcggggccg ccctccttcg ccgaggtcgc cgacgcgtgg
     8641 gccacggtga ccggcgagga cgtcggacac ggcacgccgc tgtggctcaa tgcgttcgac
     8701 gacaccagcc gacaggccac ccgctaccgg cagggccggg tcctgctggc cggcgacgcc
     8761 gcgcaccttc agatgcccgt cggcggccag gcgctcaacc tcggtctgca ggacgcctcc
     8821 gacctggggg gcaagttggc cgcgcgagtg ctggggcggg ccggcgacga ggtcctggag
     8881 agctaccacg acagccgtca tccggtgggc gcgcgcacgc tgtccaacat ccgcgcccag
     8941 acactgctgc tcctcggcga ccagcaggtg gagccgctgc gatccatctt cggggagctg
     9001 ctggaggacc gggcggtccg ccgccacctg gccggaatga tcagcgggct cgacacggcc
     9061 gcaccggaac ccggcgtccc gcggccgaca cccgcgccgg cgcccagccg gcctcacctg
     9121 acacctgaga ggaccaccgt gagcaggctc atcgacaaga ccgcgctggt aaccggctcc
     9181 agccggggca tcgggcgcgc catcgccacc cgactggcgg ccgagggcgc cttggtggcc
     9241 gtgcactacg cctcgaacgc cgacgcggcc ctggagaccg ttgagttgat cgagaaggac
     9301 ggcggccggg cgttcccggt gcgggccgaa ctcggcgcac ccggcgacgt gcaccagctg
     9361 ttcctgggcc tggagaaggg cctgaaggag cggatcgggg agaccaggct cgacatcctc
     9421 gtcaacaacg cgggggccat caccccggtc ggccagcagc cggaggacac caccccggag
     9481 gagttcgacc acctgttcgc ggtcaacgcc agggcgccgt tcttcatcgt gcagcgggca
     9541 ctcggcatca tccccaccgg cggccggatc atcaatatct cctccggttt gacccggttc
     9601 tccaacccgg agcaaaccgc ctacgccatg accaagggcg ccatcgaaca gctgtcgctg
     9661 cacctggccc ggcatctggc gccacggctc atcaccgtca acagcgtcgc tcccggcatc
     9721 accgacaacg gcggcgccgt gttcgacatc cccgaggcgg tggagcaaat ggcgcagctg
     9781 tcggccttca agcgggtcgg caaggccgag gacgtcgccg acgtggtcac cttcctcgcc
     9841 accgacgagg cgcgctggat caccggagct ttcatcgacg ccaccggcgg cacgctgctg
     9901 tagggcctgg cccggcatgc cgccccgccc gggggtcgcc aggacccggc gccccccggt
     9961 cccgcgacgg tgcggcgcgc gcaagcgcag ccgacgtcgc ccctgcgtga ccgcacacaa
    10021 ttgggagtgg agcatgaagg tcggcttgtt gttcgacgcg cgcaaccccg aggggtggca
    10081 gcgcccctgg gcagaccact acgcgcagat cctggagcta tgtgaggagg ccgagctgca
    10141 tggcgccgac ggggtgtggt tcaccgagca ccacctcttc tccgacggct acctccccca
    10201 gcccctgacg ctcgcggcgg cggccgcggc ccgcacccgc cgggtgcgga tcggcacctc
    10261 catcctccag cccgcgctgc gcgtgccggc ccagctggcc gaggaggcgg cggtggtcga
    10321 cctgatcagc ggcggccggc tggagctggg tgtgggcgca ggctaccggg tgccggagta
    10381 cgagctgttc ggcgcgaaca tcaatacccg cttccggcgc acggaggctc acatcgtgga
    10441 gatgcgccgg ctgtgggagg agcgcggcgt cacgccgctc ccgatccaag acccggtacc
    10501 gctgtggggc ggcttctacg ggccgcgggg ggcgcgcatg gccggccggc tgggtatcgg
    10561 cctgctgcac atcaacccga cgatgttcga gcactatcgg cagggcctgg ccgagggtgg
    10621 gcacccgccg gagaccgccc gggtcgggga cctggtgccg atcatcctcg ccgacgaccc
    10681 ggacgcggcc tggccgcgag tcgcgcccta cctcgcccac cagatgaaca gctaccggca
    10741 ggcgtcggtg gagggtaccg acaccccgcc gccgccgctg atccgcgccg aggagctccg
    10801 caaccgggac cccgacgggc catggggcat gttggagata ctgacgcccc aggacgcggc
    10861 cacgcgcatc accgagctga cccggggact gcccgtcacc cagctcatct tctgggcgag
    10921 cgtggccggg atgcccgacg acctggtcgt acggaacatc gaactgatca gccatgcgct
    10981 gccgccgctg ttgcgggagg cggccgaagt cggggccgac gcgcccgccg gcgtctgagg
    11041 tcccggcccg cactgcacgc gcggcccagg ccgagtcctt catgccgcat caggtgcgtc
    11101 agcagcaccc acaccacttt ccacagtgcc gaggggtatc catgggcagc agcctgcaag
    11161 gcaagacagc gctggtcacc ggcgccagcc ggggcatcgg gcggggcatc gcgcggcgcc
    11221 tggccgagga cggtcgcagt ggtcgacgtg caactacgcc acgaacgaga gcgcggcgaa
    11281 ggagacggta gcgctgatcg aggaggccgg tggccgcgcg ttcgcggtgc gctcccaact
    11341 gggcacgcag gactcgatcc agaagctgct gtcggcggtg gaggccgggc tggcagagca
    11401 caccggtggc acgacgctgg acatcctggt gaacaacgcg gcggccaccg gcttcgcggg
    11461 cacggcaccg gaggcggtga ccgaggagat cctggaccac tgctacaccc tcaacgccaa
    11521 ggtgcccttc ctgctcaccc agcaggcgct gcggctcatc ccggacggcg gacgggtggt
    11581 caacatctcc tccggcgtca cccacgccgc cttcccgccg cagatcgcct acgcgatggg
    11641 caagggcgca ctggagcaga tcacgctgca cctggcgccg gtgctggcgc atcggaacat
    11701 caccgtcaac accgtggcgg cgggcatcac cgacaccggc gacccggtgt tcagcaatcc
    11761 cgaggcggtc gaggcgatgt ccgcgcagtc ggcgttcaag cgagtcggca cggtctcgga
    11821 ggtcgccgac atcgtggcgt tcgtcgcctc cggggatgcg cgttggatga ccggcgcgtt
    11881 cgtggatgcc accggcggca ccctgctcgg ctgagcagac cccacccgca cgacgacagc
    11941 atgagctgag gaggcgacga tgaacaacac gaccgtgtcg gcggtgggct tcgcccgccc
    12001 caggcccgag gtggccgagg agttcggcgc caagctggtc gcgctcgccg cacaggcgcg
    12061 caccgagcag ggcagcatcc acacctacat ccaccgcgac atcgccgagg agaacctctt
    12121 cgtcttctac gagacgtggg agtcccagac ggacgtggac cggcacctgg accagccgta
    12181 catgaaggag ttcctgacca gcctgccgga ctacctccaa gaggagctga aggtgcatca
    12241 gctggcgctg gtcggcccgc tgtcggagcc ggccgccgat cccagcgacc cggcggagat
    12301 gaaccagcgg tacgtcgacg cctacaacgc cagggacatc gacggcatcc tggcggtcta
    12361 cgcgcctggc gcccagtcgg tctggcagcc cggccaggcg gtcaccgcgg ccgaacaccg
    12421 cgacaccgtc gtggagttcc tcaagcgcga gccgcggctg accgccgatg tgcgggagac
    12481 ctacgtggtc ggtgacaccg ccgcgctggt cgtcgactgg agcctggagg tgcccggagc
    12541 cccggagctg accggcaccg ggcggggtct ggacgtactg aagaggaacg cccagggcca
    12601 gtggcgctac atcatcacca atcctttcgg gagcccgtga caccggcgcc taccgacaac
    12661 ctacggagac gacatgggtt cgatcagggt ggaggacggc tacctctcgc tgttcaacat
    12721 cttccacatc gaaggggcac ccgggcagga ccggctgttc gagacgtttc gcggcctacc
    12781 cccagccaaa gtccagccgg gtctcgtctc gggcaacatc caccgcggca ccgacggccg
    12841 gtccgtcctc aactacgccc agtgggagag ccaggcagcc tacgacgcct tcagagccga
    12901 gaccgcaacc aagggccggc tcgaccaggc cctgaccttc tcccggatgg acagcgtcgc
    12961 caccgaggtg gtccacacct ggcagccggc cccccggctg tcggtggacg acggcctgct
    13021 cacggcggtc gtgctgatca ccaccacccc cgagcaccag gccgaggtgc tgaaggaact
    13081 ggtccaggac gacccggcac tggccgacac accagggttc gtctccgacg cggtgcacag
    13141 gggcctgtcc ggggaacacg tcgtcaaata cgcccagtgg gaggacgagg cggccttccg
    13201 gtcctacctc ggcaagcagc ggtcgccgtc ggcagtggag tacctgatca gcgtcgagat
    13261 ccacctcagc cggctcgagt acgtgcgagg ccggtcgtga ccgccgccgg cagctggccg
    13321 gaccccgcgg cggtccgggt gacggccgag tccgccggcc gaggcgccgc cgaggcggac
    13381 gcctcgggac ggatcggcgc cgagaccgtc gaggcgctga cggcggccgg cttccccagc
    13441 gccttcgtgc ccgagcgctg gggtggcgcg gacgccacct gcggcgcggt ggccaaggcg
    13501 gtggcggaga tcggcgcggg ctgtgcgtcc gcggcctgga tcgcctcgct gctggcctac
    13561 agcgggcgct tcgcggccta cctcccgacc gagggccagg aggaggtgtg ggcgaaggga
    13621 ccgcgcaccc ggctggtcag ctcgatggtg gcatccggcg tccgggccga accgacggcc
    13681 ggcggctggc ggctgtccgg ctcctggctc tacgtcagcg gcgttgcgtt cgccgactgg
    13741 gccctggtca gctcctcccc gccgcgcgag ggcgaccgga acgtgcgggt gttcgccgtg
    13801 ccccgcgacg tgttcacgta cgaggacacg tgggaggcga tcggcatgca cgccaccggc
    13861 agccacaccc tcacggtggc cgacgcgttc gtgccggaat accgggcgtt cgtctgggac
    13921 gacatgcggc agggcatcct ggcaggaccg gccacccggg cccagtccgc cccgctgttc
    13981 tcggtgaacg gcctgacctt cgccgcgccg atcctgggcg cggctcgcgg cgcccagatc
    14041 gtggccgggc agcacctgtc cgtgcagccc aacggtccgc gcaccgcggc aagggaatcg
    14101 agcctgctgt ccttcgcacg cgcggcgacg gagatcgacg ccgcggagct cctgctgcag
    14161 cgggttgccg acaccgccga cgggggcctg ctcgacgacg gtctggccgt ccgcagccac
    14221 cgcgacgcaa ccgtggcggt gcagatcctg atgggcgcgg tggaccggct gttcggggtg
    14281 accggcaccc ggggccaggc cagatcgcac cgcatgcagc ggatctggcg cgatgtgcat
    14341 accgccggct cgcatgccgc cctgcagttc gaaccggcgg gcctgggcta cgcccggcgc
    14401 ctgctgtcgg cgtgaccggt ccgggccggc cactgacgtc cgggcccggg cccgccggcc
    14461 tgcgcccccg cgcgcggggc cgttgatctg tgaccgcatt ccaagctcga aaggaacccc
    14521 ccatggctgc ccgggaattc accctcgacg acctgcgtcg catcctggtc gaagcggcag
    14581 gcgccgacga gtccgtcaac ctcgacgtgg acatcctcga caccgacttc gagtcgctca
    14641 actacgagtc gctggccctg ttggagaccg gcggtcgcat cgagcgtgag tacggcatca
    14701 cgctggagga cgacgcgctg agcatcgagc acacgcctcg caaactgatc gaactggtca
    14761 acgcccacct gaagacgacg ggctgacgat gaccgccacc agcggcgaac cgcgaccggc
    14821 ggtgggcgca cgggtacgcc gcatccgggt gagtgccggg gacctcgcgc tgtcggggct
    14881 gctcggcgag ccgctggacg caccgccccg ggctgtcgtg gtcgccctgc acggcgctgg
    14941 tatgagcgcc gagtacttcc acggcagggc ccatcaggac gtgtcgctgg ccaccctggg
    15001 tacgctgctc ggcttctccg tccttgcgct ggaccggccg gggtacggcg cctccgccgc
    15061 ggatgcgccg cacggcagga ccctggatga acaggccgcg gccgtccatg cggccatggc
    15121 gtggttcgcc gaccgccacg cggtgggcgc ggggttcttc ctgctgggcc actcttacgg
    15181 cggcaaggtc gcgctgactg cggccgccca gcccgccggc gaggacctgc tgggcgtcga
    15241 cgtgtcggga tgcggccagg agtacgccgt gcccgacggc ctcctcgacg accgccgctc
    15301 ggaggactgg acgaagaact ggggtgcgct gcgctgttat ccgcccagca cgttcacgct
    15361 cagcaagtcg gtggtctcgc cggtaccgaa acaagaacgg gccgaggcac ggcggtggcc
    15421 cggccggttc gcccaggtcg ccgcggcggt ccgtacgccg gtccggttca ccttcgccga
    15481 gcacgagtca tggtggcggc acgacgagac cgccgtcggc gatctgcggg ccagattcac
    15541 ctcctcgccg cgggtgctgg tggagcgcca gccggacagc ggccacaaca tcagcctggg
    15601 ctggagcgcg cgttcgtacc acctgaaggc actgggcttc ctggaggagt gcctggcctc
    15661 ggacgcccgg cgtcgcgaac gcgcactgca tcactgaccg cgccacaccg aatcacggga
    15721 gacaacagga catgtcgcaa caggagaagc gttccgcact cgtcaccgga gccaccagcg
    15781 ggatcggcct cgcgatcgcc cggctcctgg ggagggaggg ctaccggctg tacatcggct
    15841 cgcgcaacgc cgacaacgtg gcctcgaccg tgaagcagct gcgcgacgag ggcgtggagg
    15901 tcgacggctc ggccgtggac gtccggtcgg gcaccgacgt gcgcgccttc gtgcaggcag
    15961 cggtcgacgc ctacgggccc gtcgacgtgc tggtcaacaa cgtcgggcgc agcggcggcg
    16021 gggtcaccgc ggacattgag gacgagttgt gggaggacgt catcgagacg aacctcacca
    16081 gcgtcttccg ggtgacccgc gaggtgctca acaccggcgg aatgcgcggc agggaccgcg
    16141 gccggatcat caacatcgcc tccacggccg gcaagcaggg cgtggtgctc ggcgcgccgt
    16201 actcggcctc caagcacggc gtcgtcggct tcaccaaggc gctgggcaac gagctggcgc
    16261 ccaccggcat caccgtgaac gcagtgtgcc cgggctacgt ggaaacgccc atggcgcagc
    16321 gggtccggca gggctacgcc gacgcctacc acaccaccga ggacgcgatc ctggagaagt
    16381 tccaggccaa gatcccgctc ggccggtact caacccctga ggaagtggcc ggcctggtcg
    16441 gctacctggc ctccgacacc gcagcctcca tcacctcgca ggcgctcaac gtctgcggcg
    16501 gactcggcaa cttctgacct tcgaggagat gacccatgac cacccgtgag gtcgaacacg
    16561 agatcatcgc cgacgccccg gccgaagccg tctatcggct catcgccgag gtcgagaact
    16621 ggccgcggat cttcccgccg accatccacg tggagtacct ggaccggggc gtcgacgacg
    16681 agcgcatcca catctgggcg accgccaacg acgagccgaa gaactggacc tcgcgccgca
    16741 ccctgtcccc cgccgacctg cggatcgact tccgccagga ggtgtcgaca ccgccggtgg
    16801 cggccatggg cggcgcgtgg atcatcgagc ccgtcaccgc gacccgctcg cggatccggc
    16861 tgctgcacga ctaccgggcg gtggacgaca ccccggagaa cctgaagtgg atcgacgagg
    16921 ccgtggaccg caactcgcgc gcggagctgg ccgcgctgcg caccaacgtc gagcgcgccc
    16981 acgccgaggc cgagctcacc ttctccttcg aggacagcgt cgcggtggac ggcgcggtca
    17041 aggacgccta cgacttcatc aacgaggcat acctgtggtc cgaacgactg ccgcacgtgg
    17101 ccaaggtgcg cctgtccgag gacactccgg ggctccagtc gctggagatg gacacgcagg
    17161 cgcaggacgg ctcggtgcac accaccaagt cctaccgggt gacgttccca caccacaaga
    17221 tcgcctacaa gcaggtgacc ctgcccgcac tgatgaacct gcacaccggc tactggacgt
    17281 tcaccgagag cgacagcggc gtcacggcgt cctcgcagca cacggtggtg ctcaacaccg
    17341 cgaacatcgc ccggattctc ggcgatgacg ccaccgtggc cgatgcccgg gagtacgtgc
    17401 gcaacgcgct gagcaccaac agccgggcca ccctcggcca cgcgaaggcg tacgccgagg
    17461 gtcggcgctg aagcccgcag aggaggaacg gcggtgggcc gtgaggccgt ccgaccccct
    17521 cgggcccgac gagccggctg acttgtcgct gtggttggtc cggccgccac ggccaggaac
    17581 tcccgcggcg tcccggctgg cggtcgacga gctggacgcg tcggagaacg ggcgggcgga
    17641 cttgttcgtg cacccgcggg accggttgca gtacctggcc gcgcacatcg cgctgcgccg
    17701 ggtgctggcg gcccgtaccg ggtgcccgcc cggggcactg cggctggggc gggagcccgg
    17761 gccgcccggg acgaatttca gcggccggcc ggtgctggtg gaccctccgg ccccggtgca
    17821 cttctcgctg tcccacagcc acggcctgat cctcatcggc gcggcgtcgg tggtggtcgg
    17881 tgtggacgtg cagcgcgtgc cgacgctgca gacggtgcaa ctgtgcgggc cctccttgca
    17941 cccggcggaa tggagcgagt tggccaagcg gcccgcggcg cgacagcctg ccgccttcgg
    18001 gcggctgtgg gcccgcaagg aggcgtacct gaaaggtctg gggacgggcc tgcggcgcag
    18061 cccggcgctg gactacgtgg gggacgccgc ggatgtctgc gctccgccca agccgttcgg
    18121 ctggatcgtc cgggacgtgc cggtcggacc gcagtacacc gccgccgccg ccctggccgt
    18181 cgccacagaa ccgaccatca ccctgcgctc attgcccgtg tcgtgcctgt acggcggcaa
    18241 cgcgggacag ccgctgtccg cggcaccgct actggcttgg aggaggaaag gttcatggac
    18301 gcttcggtgg tcatcgtggg ggcgggccct gcaggcctga tactcgccgg ggaactgcgc
    18361 ctggcgggcg tcggcgtgac ggtcctcgaa cgcctggaac agcgcaccgg cgagtcccgc
    18421 ggaatcggct tcaccatccg caccatggag gtgttcgacc aacgcggggt gctgcgccga
    18481 ctcggcccga tcgagacggc cacggccggg cacttcggcg gtctgccgct ggacctgggg
    18541 gtgctggggg cggcgcaccg agctgctcgc accgtgccgc agtcggtgac cgaacaggcc
    18601 ctggagggat gggccaggga gttgggcgcc gacatccggc gcgggcagga ggtccaggcg
    18661 ctcgaggaca ccggtgacgg cgtgaccgtc acggtggccc gcggcgacaa ccgggaaata
    18721 cttcgagccc gctacctggt cggctgcgac ggcgggcgca gcaccgtgcg caagctggcc
    18781 gggttcgact tcccgggcac cgacgccacg accgagatgc tgttggcaga cgtccgcggg
    18841 gtggaactcg aaccgcggat gagcggccag cagatcggca acggcttcct gatggtcgca
    18901 aagctgcccg gcggcatcca ccggctgatc gtgggcgaac gcggcatcgc accgcgccga
    18961 cgtaccggcc ccccgccgtt ctccgaggtc gccgacctgt ggaagcgact gaccggcagt
    19021 gacatctcgc acgccgagcc ggtgtgggtc agcgccttcg gcgacgccgc gcggcaggtc
    19081 accgagtacc ggcgcggtcg cgtgctgctg gccggcgacg ccgcccacgt tcacctgccc
    19141 gccggcgggc agggcatgaa caccagcatc caggactccc acaacctggg atggaagctg
    19201 gcgtcagtgc tggccggcca cgccccggag gcgctgctcg acacctatca cagcgagcgc
    19261 cacgaggtgg ggcggcggct gttggtcaac acgcgggcgc agagccagtt gatcctgggc
    19321 ggcgaggagg cgcagccgct gcgcgaggcg ctgtcggagc tgctccagta cccgaacgtc
    19381 gtacgccact tggcggccaa ggccagcggt ctggacatcc gctacgacgt cggcggtggc
    19441 accaacccgc tgctgggccg ccggctgccg caccttccgt tgaccaccgg cgcccgtagg
    19501 accagcagca ccgagctgct gcgggccggc cgcggcgtgc tgctggacct cggtgacaat
    19561 gccaggctgc gtgaccgcgc aacgccgtgg cggaaccggg tcgacgtcgt gaccggaacc
    19621 gcggaccccg agcacgctct cccgggcggc accacggcgg cgctggtacg ccccgacggt
    19681 catgtggcgt gggccgcacc cggcagccac caggacctgg cgacctcgct gacccgctgg
    19741 ttcgggccgg ctacatgacg ccgccgagga cacgcgacgg acgccgccaa gtcggtgcag
    19801 gccgatccgc cctggtagcg gatcggcctg ccctgccctg ctccgcagga gtccgtatcc
    19861 tcccccgcct caaagcgggg gtatccacgg aggaatccag atgaccgctg agtccgtacc
    19921 cgtcgccgtt gtcaccggag ccaacaaagg aatcggccgg gagatcgccc ggcagctggc
    19981 cgtgcgcggt ctggtcgtct acctgggagc ccgcagcgag cgacgcggcc gggaggccga
    20041 gagcgcgctg cgcgccgacg gcctcgacat ccgcttcctg cacctggacg tcaccgacga
    20101 gacctccgtg gcgctggccg caaaacggct ggaggacgag gtgggggtgg tgcacgcact
    20161 ggtcaacaac gccggtgtcg gcggccccta cctgcccccc agtaggacct cggctgcgca
    20221 ggtgcgggag acctacgaca ccaacgtctt cggtgtcatc actgtgacca acgcactgct
    20281 gccgctcctg cgccgggcag ggtcggcccg gatcgtcaac gtcagcagcg cggtcggctc
    20341 gctgtccgcg gcggcggcga acgtcgaccc gaccggggtg cacctgcccg gcgagttccc
    20401 gacgctgctg gcgtacaaca cggccaaggc cgcgctcaac tcggtcaccg tgacgtacgc
    20461 caacgaactg cgcggcaccg gcatcctcgt caacgccgcc tccccgggct tcgtggcgac
    20521 cgacatcaac ggccatcacg gcatcctcac ccccgagcag ggcgcgcaca tcccggtgct
    20581 cctggccacc ctcggcgagg acgggccgac ggccaccttc ctgggcgaga acggcacgcc
    20641 cgaaggacag gtgctggact ggtgaccgga tcccgtcccg cgcctgccgg ccgcccggtg
    20701 gtgcgagagc gctgggacgc acgccggcgg atcctgctgg cggtgctgtc cggcaacatg
    20761 ctgctggacg cggtcgaggt gtcggtggtg ctcatcgccc tgcccacgat cgccgaccgg
    20821 ctgggcctga gtccgctggc cgcccagtgg ctgatgagcg gcttcgctct cggcttcgcc
    20881 gtgctgctgc cgctcgggcc ggtgctcgcc ggccgggtcg ggcgtcgtcc ggtctatctc
    20941 ggcgcgatgc tgctgttcgg cctggcctca gtggtcggcg ggctggtgga cggtctggcg
    21001 gtgctggtgg tcatccggct gctgaagggg gcttgcgcgg ccctgaccgc cccgatggga
    21061 ctggccatca tcagcgacgt ctttcccgac gggccgcagc gccggcgagc cctcgcggtg
    21121 tactcgttgt tcggcgccgg cggcttcacc tccggactgc tgctcggcgg ggtgctgctg
    21181 gaggcgggct ggcgctgggt cttcgtcttc cccgcgccgg tcgccctggt gctgttcctg
    21241 ggcggcatgc gcgtgctgcc cgggacccac agcggggcac ggccggggct gccgcgtccg
    21301 gcgctgctgc gagagggctc cctgctgcgc tcggcactgg gggcggccat actcaacggc
    21361 acctatcaga gcctgctgct ggtgatggtc ttccagtcca tgggcggctt cggctgggca
    21421 ccgtggttca ccgcactggc gctgctgccc gcgtgcctgc cgctggcggt gaccatcccc
    21481 ttcgccgggc gactgatcgc ccggtacggc ggcggccggc tgatcacgct cggcgcgctc
    21541 ttccccctgc tgggctacgg actgtatctc gcccggcccg agggcagccc gtacgcgctg
    21601 gggatgcttc cggcgctgct gctggtggag gccggcttct gctgctcgtt cgtggccctc
    21661 aacatgcgcg ccaccgcctc gctcgccccg gccgaccgcg gcgcggcggt gtcgctgtac
    21721 cagatgtgcg tgcagttggg cgccgcggtg ctgctgccgc tggtcgcgct gttgctcacc
    21781 cacggcgacg ggccgcgccc ggcgctgacc ctcatcacgg cggccggcgc gctcggcctg
    21841 ctggtcccac tcgccgtaca ccgggtttcc gcccggtccg accccggccc tgacccgcga
    21901 gcccccgacg ggcccgcgcc ccacccgtcc cgcacaccac cacaaggaga cctcccccat
    21961 ggctgaccaa tcgcccgaga cgcaggtgca tcccggcccg atcatgggcc tgatggccgg
    22021 ctactggcag gtgaggatgt tgctggcggc cctggagcac gacatcttca ccgagctgtc
    22081 gaaggggccg gccacctccg gcgaggtcgc cgaccgcatg ggcctggtcg agctcggcac
    22141 acatgacctg ctcaccggcc tcggccacct cggcctgctc caggtcgccg acggcaggtt
    22201 cgccaactcc cccctggccg accgcttcct ggtccgcgga ggcccggaat tcctcggcgg
    22261 atacctgcgg ttctgcgagc aggagctgaa cccggcctgg gacggcctgg cgacctcgct
    22321 gcgtaccggc cggccgacca accgcgccgc ggtcgtcggc aacccgtacg acaccctgta
    22381 ctccgacccc gacgccaccg acggcttcct ggacagcatg gacctgctca gcactcctat
    22441 cggactggcc atcagccggt acgactggag ccagtactcc tctttcatcg atgtcggtgg
    22501 tgcccgcggc aacttcgccc accaggtggt caccgagaac ccgcacctga ccgccggtgt
    22561 cttcgacctg cccccgctgg agggcacctt caagcggcac atcgagcggc tgggcgcgac
    22621 cgcctcggga atcagcttcc acgggggcga cttcttcaag gacaagctcc cgaaggccga
    22681 tgtgatcgtc ctcggccacg tgctgcacaa ctggggtgtt gaagaccgcg tccagttact
    22741 gaagaacgtc tacgacgcgg tccggccggg tggcgccgtg ttcgtttacg acccgatggc
    22801 cggcggcgag cagccgtccc tgcacgcggt gttggcgggg ctggcgatgc tggtgtggtc
    22861 ccggggcggt cacgagtact ccgtcgagga actgcacggc tggctacggg aggcgggttt
    22921 ctggccggag accgccgagg tccccggcct gcacgaggac gtgctggtca tcggccacaa
    22981 ggacgcctga caggcgcggc gccggacgcg tcggcggttt ccgctccacc gtgcgtccgg
    23041 cgggcccgag ctccgcccgt tgctcgccgc gatgaccgcc gcccgcgacg gcaacctgac
    23101 gaagctgccg gagacgggcg aggggatcgt ggccgagctg ccggcgggtc ttcaaccaga
    23161 tcctcgaccg cagcgtcctc cctcaccacc cactctctcc ggagtcttga catgaagatc
    23221 gaaaacagtg ttggcgtcgt caccggcgcg gccagcggca tcggcaaggc catcgcagtg
    23281 gcgctggtcg aggcaggcgc acgtggcgtc gtggtctccg acatcgatgg cgagggcgcc
    23341 gagaaggtgg ccgcgtcgat cggtgacgcc gcgatcgcgg tgcgggccga cgtcaccgac
    23401 gaggccgccg tccgggcgct ggtggcgcgc gcccgggaac ggttcggcac catcgacctg
    23461 ttcgtctcca acgcgggcct tcccgtgaca ggcgggtacg agacgtcgga cgaggactgg
    23521 aagcgcgccc tcgacgtcaa cttgatggcg cacgtgtacg ccgcgcgcgc ggtgctcccg
    23581 acgatgctgg cgaccggccg cggccacctg ctgcagacga tcgcggcgtg cggggtgctc
    23641 accgctttcg gagcggcggc gtactcggtc gccaagcagg gcgcggtggc gttcgccgag
    23701 tacatcgcga tcgagcacgg cggccagggc atcggcgtct cgtgcctgct gccgcaggcg
    23761 gtcgacacgc cgatgctggc cgccggtgtc aagagcagcg agcaacttgc gctgctcaaa
    23821 gcgcactcgg aggtgctgga gccggggcag gtggcggcgg ccgccctgca gggagtggag
    23881 gagaaccgga tacacatcca cacccacacc ggctcggcgg agtccttccg actgcgcgcc
    23941 caggaccccg accggtgggt ggccgagatg cgggcgatcc gttccggccg gcccgccgcc
    24001 tgatcgagga gacggtcgcg accgtgcggg cgccggagca ggtgaaggcg cccgcgtcag
    24061 gccgaccggc ccatcccgcc gccctgcttc gtcgtactgc gcgtcacaga ggaaggagat
    24121 cgccatggac gaggaaaaac tgcggctcgt cgtgatcatc ggatcggccc gcgagggccg
    24181 caccggtccg gccgttgcga ggtggttcgt cgaggagacc aggtcttccg ggctgttcga
    24241 tgtggacgtg atcgatctcg gcgacgtcga actgcccctg acactgacgc gggtgcccgg
    24301 cgccgagttc acgcgggtgc tcgccgacct cggcgcacgc ctggagtcgg ccgacgcatt
    24361 cgtcgtgatc acccccgagt acaaccacag cttcaccgca ccgctgaaga acctgatcga
    24421 ctggcaccgc acccagtggc aggccaagcc ggttggcttc gtcagctacg gcgggctgtc
    24481 cggcgggctg cgggccgtgg agcagctgcg ccaggtcttc gccgaactgc acgccgccac
    24541 gatccgtgac accgtcagct tccaccaggt ctgggagcgg atcggcgagg acggccggct
    24601 gagcagctcc gacgccacga tcccggccaa ggtgatattg gagaagctgc agtggtgggc
    24661 tgcggcactg agggacgccc gcgtgctgcg gccctattcc gcctgatcag ggcgtccgac
    24721 caccctgccg gaaggtgacc agagggggac gagttgagcg ctgcccgagt gtgcggccac
    24781 cgcgcaccgt ggccggacgc cgggctgatc cgggccgctg cggccaccgc cggccgccac
    24841 gccttgcatg cggatgtgtc ggggagcctg tctccggaga cggtcgcggc gctggccgcg
    24901 gccggcttcc ccggctgttt cgtgccggaa ccgctgggcg gggccggcgc cacgttcggc
    24961 gcggcgacgc gggcagtggc ggcgatcggc gaggagtgcg ccgccgctgc ctggaccgcg
    25021 tctgtgtggg cgtacagcgg tcggggcggc gccttcctgc cggccgaggg gagggcggag
    25081 atatgggcaa agaacccgca ggcgcggctg gtcagctcga cggccgcctg tggggtgcgg
    25141 gcggccccgg tggccggggg ctggttgctc tccggcgcgt ggcgctgcgc cggcggagcg
    25201 gagtctgccg actgggcgct gctcagctcg gcggtgccgc gcaccggcga ccggtcggtg
    25261 ctgatgttcg ccgtggcccg gggctccttc accctcgccc actgcggcga gtcctcgatg
    25321 ctgggcatcc gggccgccgg ccgccaaacg ctggtcgtgg agcgcgcgtt cgtcccggag
    25381 caccgggcct tcgtgtggga cgacatgcgg cggggccgcc cggccggtcc ggcgaccacc
    25441 gcccgcctgg cccccctgtc cgcagtgacc ggcctggcgt tcgcgacgcc gatcctgggc
    25501 gcggcacgag gcgccctgcg gctggccgag gagcgcctcg cggtgcggcc gcgccggagc
    25561 gcggcgagga gttcggtacg gatgccgggc cgcgtcgcgt tcgcccgctc ggccgccgag
    25621 atcgacgcgg cggccctcct gctgttccgg gtggccgagg acgccgacat gtgtcggtcc
    25681 gacgacacac cgaccgcacg cggccggcgc gacagcgccc ttgcggcgga actactgaca
    25741 gctgcggtgg accggctgtt ccggtcggcc ggaagccagg gccgggcgtc ctcccacgcg
    25801 atgcagcgca tctggcggga tgtgcacgcc gccggcgcgt acaacgccct ccggttcgag
    25861 tccgccacga tcggcgacgc acgcgggctg ctgtccgtct gacacgagga acccgagagc
    25921 ccggcacgcc cacgctcatg cgtcaggcgg tcgtatcgag ttcgctcccg tcctgggtcg
    25981 cgtcggtccg gtcaccgacg aagaccaccg gaaccttgtt gtccagcaca aggcggccca
    26041 gcaggtgggc cagcgtatcg cgctcgtcat caccgagccc ggtcgacagt tcctgtatgc
    26101 ggcggcaggc atcggtgtag aagcggtcgg cgagccgcgc tccccggccg gtgagcgcca
    26161 cccgcaccgc acggctgtcc tgcggatcgg cttcgcgccg gaccaggccg ttgctctcgg
    26221 tgcggtcgac cagaccgctg agactggact tcgccagccc cagcacggag ctcaactcgc
    26281 ccattccgta gggctgtccc atcagtacgc acagtagttg gccctgctga gacgtgaggc
    26341 cgtactcccg ggcagcccgg gcatacacgg agtccaccag gaacgaggac cttaccagtg
    26401 cgctcacaat ccccatctgg ccttcatcat gcttagccac accgacagcg taccttatcg
    26461 gccataaagt tcgcaccatg aaccacttac ggatgcacgc cgttcggttg cagcgcttcg
    26521 ccagagcata tcccgtacgc gtcacgccga ttgcggttcg tgctacgaac tagtatagtt
    26581 cgtagcacga acccaatggt tttagcggga tttcgaaagg tgacccatga gtgcaacagt
    26641 cgcggtcgtc ggcggagggt acggcggcgc cgccgtcgcc aaggctctcg aagccgaagc
    26701 cgatgtcatc ctcatcgacc cccgggacgc gttcgtcaac gcggccgcct cgttacgcgc
    26761 gctgacccag cccgactggg cgggcaacgt cttctacccc ttcgacacgc tgctcaccca
    26821 gggcaaggtg atccggggcc gcgcggcctc ggtcgacccc cgcggcgtca ccctggaatc
    26881 aggtgagcgg gtggacgcgg actacgtcgt actggccacc ggctccaact acgcctaccc
    26941 ggccaagccc gtttccgaca cggtcagcgc ggcgctggag gacttccgtc gcacccacaa
    27001 ggaggtgctc gacgccgacc gtgtactcat cctcggcgcg ggtccggtcg gcctcgaact
    27061 cgccggcgag atcaaggagg tctggccgga caagcaggtg gccatcgtgg acccgatcgc
    27121 cgaactcctg cccggcttca agcccgaggt cgtcgcggac ctgcaccagc agctcgagga
    27181 actcggtatc gagctgcggc tcggcaccag tctgaaggcc ctgccgagca ccgagccgaa
    27241 tcgcaccgga accttcaagg tcaccaccga cgccggcgac gagatcaccg ccgacatctg
    27301 gttccgtgcc ttcggggtgg acatcaacag cggctacctc accgacggcc ggttgaccac
    27361 gctgaccccg cagggccagg tcccggtgac cgagaagctc aacgtggacg gttacgagca
    27421 cgtctacgcg gtcggtgaca tcacagacgt cgcggagacc aagatggccg ggtacgcgat
    27481 gcagcacgcc gaggtggtcg caaagaacat cctcgcgcag atcaagggcg agcagcccga
    27541 ggccgtctac cagccgctgc ctcacccgat gatcctgctc ccgctcggcc cgagcggcgg
    27601 tgtcggacag ctgccctcag cggagggccc gttcgccgcc ccgcgcaccg tcgtctcgga
    27661 gtacaagggc tcggacctgt tcaccggtcg cttcatcgga cagttcggtc ccaccgccgg
    27721 ctgaccacac ggtcgccgcg cgcccccgtc ggccgtccgt cgggggcggg cccggcctcg
    27781 tccgtcattc cacgccgtac gcgtcgcggc gccggtcccg gccttctcag acgtgtccga
    27841 gccggaaccc cacaccgcgc accgtgatga tcgactcact ggcgccgagc ttactccgca
    27901 ggctgctgac gtgggtgtcg agagtccgca cggaccacga gccgccccat atccgcacca
    27961 tgatctgttg acgtggaatc acgctgcccg gttgagaggc aagcaggtgc agcaactgga
    28021 actccttggg cgtcagctgg acgtccttgc cgtccagagt gacctggcgc gaggttatgt
    28081 cgatccgcag ccgtccgtgg gcgacgacgt ccgccgatgt gttccgcgga gtgatgcgcc
    28141 gcatcaccgc ctcgatacgt gccatcagct cccggaagcc gtacggcttg accagatagt
    28201 cgtcggcgcc ggcctgcagg ccgagcaccc ggtcgagttc gctctcccgt cccgtgacca
    28261 cgatcagcgg cgtatcacag acggcacgga tacttcgaca gacctccagc ccgtccaagt
    28321 cgggaagatc gaggtcgatc agcaccaact cggcgtcgcc aaaggcatcc agggcctcac
    28381 ggccgtcctt ggcgaggctg acgtcgtgtc cgtgcctgcg cagcccctgc gtcagcaccc
    28441 gcgcatcgcc gctgtcgctc tcgaccacga gcacacgcca gccgctgggc cgcaccggta
    28501 aatcgcgttc gccggcggca tttgggttta tcgcggagtg gtccgccatc gtgagacaga
    28561 tcctttcgaa gagagccttg actcagcctc aggcgcgttc cgctgtgacg acagccatgc
    28621 gcgcggtccg gaggatcttg tgtctgcaca tgtacatgtg gccgtcgatg ggcggatcca
    28681 ggtatggcac ctttccccca gcgccgggag agcgtcacga gtgtgacggg tgtcggccga
    28741 agggcccgga ggacggcagg ggagcgagga accggcgggc gaactcccca tgaatgccac
    28801 cgatcacggc gcctgccctt gcggaataaa acgcccaaga gccgcgacac gcgcaaactc
    28861 ccggcaccag aaacgcagcc cccgtccaca gcacatgccg tgcagcacac gtcttaatgg
    28921 tcatccccgt ttatccacta caatgctggc tcccccttga agtgccaact tcccccgagg
    28981 cggagagaat tcccaactcc tgaaaattac atgacgcaca cattcaggtc aagggcgatt
    29041 taagttgcct ccctcacccc gcccttgcga attcaaccgc actgcctggg attacccgga
    29101 gtccgcttga cgactcacga agccacaccg gaaaatgttt acataatctt aataaatgag
    29161 ccgcccaacg cacgcacgct ggccacgtgg agggtgaatc aggaatcggg accggcgaca
    29221 ttgtgattta ttttacactc ctatcttacg gaaatttggt agcgcggcgc ggggcggcgg
    29281 ttcgaccggc tcggccggac gcgacccacc tgcccctcac cctcgagact taccgaactc
    29341 agtgatccct ctccttggcg atcgccgcac ggaccgcggg cacgatctcc ccgccccagc
    29401 gctgaagcga ggcgaggtcg gcggtgccgc cctggggcga gaagagcatg aacccggacg
    29461 cgccgtgctc cagcacggct ccggtcagct cctcgatcca ctggtcgacc gagccgccga
    29521 gccagcggcc atcgcggtca cgggtggacg acgtgggcct ggtggtgatc tgacctggca
    29581 ggttgtagac ggtgcgaatg tccagcgggt cgcggccggc cgccgtcgcg gcctggtcga
    29641 tgatcgggcg cgaggtccgg tagcgctcgc tgagccagtc cgccgcgtgg cctggaatcc
    29701 agccgtcggc cacccggccg gtgacggcca gggacttggg accgactgaa ccggtccaca
    29761 ccggcggcgc tgcgaccggt gctgggtcga tccggttgac ccggtagtga acgccctcga
    29821 aagtgactgg tgggccaccc cccgacagct tcttgaccag gacgatcgcc tcttcgaagg
    29881 cgtctaccgc ctggccggcc gtcagcggcg ggacacccag gtcggcgatc cggtcccaca
    29941 gcccgccgac gcccaggccg agcacgactc gcccgacgga cagcgcggac agcgtcgtca
    30001 ccgcccgggc cagcatcgcc ggcggccggg tcggcaggtt gctgacgttc gcgaagcccg
    30061 cgagccgctc ggtgcgcccg atgatgaacc cgagcgcggc gtatgcgtcc agccgctcgc
    30121 cgacgtatgg gtggtccgac agggagaaca ggtccagccc gtcgcgatcg gcctgtcggg
    30181 tcagacgcag tagctcaggt ccggtgtcga tcgtgctgtg cgccccgaat ccgaagacga
    30241 cttgttgtgc caccaatgcc ctgcccttcg tgtgtcgttt ttgtgtctcg tcgaccgcgc
    30301 cgtggccggt cgtggggtgg accgtcgagc gcgggaccgg gtgcgtgcgc gccgctcgct
    30361 caccaggcgt acgcctcggg tgcgggccgg ggcccgttca ccaccgggtt gaggccggga
    30421 gccgggaaca gccggtcgag cgcggtcagc acgacttcgt ccagggcgat gtccagcgcg
    30481 cgcagagagc tctccaactg cccgaccgtg cgcgggccga tgatcggccc ggtcacaccg
    30541 tcctgcgcca gcagccacgc gagcccgaca tgagcggggt cttcaccgat gtcggcggac
    30601 agcttctcgt aggcctcgac ggtctcccgg tgtccggcga gggtcgcgat cgagcgaccg
    30661 gtgttgccgc gcaaagcgcc gccttccttc gccttgcgaa gcactccgcc gagtactccg
    30721 ccgttgagcg gcgaccacgg gatcacgccc agaccgaagt gccgcgcggc gggcagcacc
    30781 tccagctcga tccacctgtt catcaggttg tagacggact gatcgctgac cagccccagg
    30841 aagtggcgcg accgagccgc ttcctgggcc agggcaatgt gccagccggc gaagttggag
    30901 gacccgaagt agagcacctt gccctgctgg cgcaggactt ggaacgcctc ccagatctcg
    30961 tcccacggcg tgctccggtc gacatgatgc atctgataga ggtcgatgtg gtcggtcccc
    31021 aggcgcttga gtgacgcgtc ggccgcgcgc cggatgttga gcgcggacag gaaccgctcg
    31081 ttgggccact cacccgtggg gatatagacc ttggtcgcca ggacggtgcg ctcccgacgt
    31141 ccgccaccgg cggcgaacca acggccgatg atcgactcgg tgaggtcggt gccgcctctg
    31201 gagccgtaca cgttcgccgt gtcgaagaag ttgatgccgt gctcatgcgc acgatccatg
    31261 atccggtgac tgtcctcttc ggaggtctcc gtgccgaagt tcatggtgcc gagcaccagc
    31321 cgagacacgg aaaggccact gcgccccaga tgggtgtact ccatgcgtca acccctttca
    31381 aacgctgccg aacggatggg cgaagccact cgggactggt cggtagtccg tcccgcgaca
    31441 gccgcaccgg agatcgcggc cgcctcggtc gtgcccatcc cctccgggaa cataactcgt
    31501 agtacgaacc gtattagttc gctctgcgaa ctgcaagctc atctctggtg gatcacctca
    31561 tcgcgtccgg cgaggtcggc tcttgagcga ctgcggaaaa gacgcctgca ccggcctgcg
    31621 acattccgtg atccgcacgg caagaattca cgcggccggg tccgttaacc ggcgaccgaa
    31681 caacgtcggt cggcagggcc gtggtggcgg gcggacactg aacttcgggg attgcgaccc
    31741 ccgcggggac tggacgcgct ggaggccgag agtgaggacg ccggcgtcga tgtcagcgcg
    31801 ctcagcaccc cggcggagtc gctactcggc ccggacggtg acgtcgagtc ctcgcgggtg
    31861 aacgcggtga atgagtattg ggcctggcag cccggcatcc gcgcacggtt cctcgggccg
    31921 gccaccgccg atgcctacgc cggagatgca ggcgccgagc aggcctgtgc cggcctggta
    31981 ccggactcct cccgccgcgc gagattaccc ggctcgcccg aggcgttgcc gaccttgcag
    32041 acggccgctc agcggggagt gccgtgctgt tgaacccggt gcaggcgccg caggaggaac
    32101 tgctgtggca cgcggtcggc cgctggcgct ggccgcgggc ttgcagaacg tggtggcgct
    32161 ttcgtcggtg ctgcacgccg gcctcccccg tcggctgccc gacccgcgcc aggtcttcac
    32221 cgcgtgcggc gctcggccac ggagggctgc tgtacgcggc cgacgcctgg ccgagcaccg
    32281 tgcgcggctc gggagaggcc gcgcgtacca ggcgccccag caacctgcgg ccggggagcg
    32341 tggcgggccc gctggaaaaa tccgtgagac cgcgaccgaa aagcacatca gaaaccgggc
    32401 cgataatgta tacgacaaat cgagaagccc agataccagt gaccgtcggt aacctgagtc
    32461 cgatccgtga cgaaggcgaa tcggtccgtt cccgggcggt gggtgaattc cccgcgaagc
    32521 ggtcgtgaac agccggcttc gaggtgcagg ccagtgccgt agaccagtgt gcacgcgtcg
    32581 aacgccgaat tgcgtgatcg agtttggtcc ggtgggtgac gagtccattg atcgccgccc
    32641 gcgacgttgg agcacttggc ggaggccgat gccgcagcgc aggtcgccga cgctgtccgc
    32701 cgcacagttt cctgcgcctg ctggcggggg cggcgccgct agcgctggag gcactgctgt
    32761 gtgcgcctgc ggcttcgcat ccggccaccg tccggcgcct gctcgcccgg ctcgacgccg
    32821 ctggactgga tcagacgatc ggcgcttccc ctccggcccg cgacccggcg cccgaagcgc
    32881 accttgggca aacagccggt actgagggcg atcgcggtgg acggcaagtc gctgcgcagc
    32941 tcacgcaccc tcgcccgccg tggcactgct ggctgcgatg gagcgcaccg gcagcctgcg
    33001 cgaacgcggc gcccactacc tggctgacgt gaagaagagc caccccggca gccagatcgc
    33061 actcgaccac tgcgaccgca tccgcgccca ccaccgcatg gagatccgac ggtgaaggcg
    33121 gtcgtgcgcc ggcgccgcaa gctgaccgac ggcaaactca ccatcgaacg cttctgcctg
    33181 atcacggtct gcctcctgga tcagaggggc actggggcat cgagaacctt ctgcaccagg
    33241 tccgcgaccg gaccttctgc gaggacgact ccaacatccg catcgcccaa ctgccccgca
    33301 ccatggccgg cctgcgcaac ctctcactcg gcgacgccac gacaagatcg ccgacatacc
    33361 tacgttcaga cgccgcctgc ggccacttcg tccgagagcc gcccgacttc acctggcagc
    33421 gcaccgaccg cgtcgaagcc ctgcgtaccg ccgccggtct ctgaccgacc cacccatccg
    33481 ccttcacgag ccgagccagg caaatccgag ggagaaagcc gtgcgtatcg ccgtaacggg
    33541 ttcgatcgcc accgatcacc tgatgacctt cccaggccgc ttcgccgagc aactgctgcc
    33601 cgaacagctg gactctgtct ccttgtcctt cctcgccgac acgctggagg tacgaagggg
    33661 cggcaccggc gcgaacatcg cctacggcct cgccctgctg gggaggtccc cggtccttgt
    33721 cggcgcggtc ggcccggact tcgccgccga ccgcgaacgg ctggaggcgc tcggcgtgga
    33781 caccagccat ctgtgggtgt ccgcacacca tcaaaccgcc cgtttcgtca gcaccaccga
    33841 cctggaccag aaccagatcg ccaccttcta tcccggcgcg atggcggaag caggaaaaat
    33901 cgacctgcgg cggatcgcgg cgtccggcgg cggcctcgac ctggtcctca tcgcacccga
    33961 cgacccgaag gcgatggtcc gccacaccac cgtatgtgtc cagacccgac tgcccttcgc
    34021 cgccgatccc tcccagcagc tggcacggct cgaccggcag gaggcacgcg cgctgctcgc
    34081 cggacctcgc tacctgttca ccaacgagta cgaggcctcg ctgctcctgg aacgcaccgg
    34141 ctggtccgaa cgggaggtgc tggaccgcgt cggtacctgg gtgaccaccc tcggcgccgc
    34201 cggcgtccgg ctccgcgcgg ccggaaggcc cgatgtcctc gtgtccgcgc tcccctccac
    34261 ggccgtcgcc gaaccaccgg tgtgtgtcgg agacgccttc cgggccggct tcctggcggc
    34321 cctcgccggc ggcgccgacg aggagaccgc cgcccggcac ggctgcgcgc tggccgtgat
    34381 cgcgctggag tccgtcggtg ggcaggaata ccacgccggt ccggccgagc tgcgccgccg
    34441 ggtgttccag ggctacggag aggtgatcag cggccgggac gagccggtcc gggaaccgtc
    34501 gcataagcag aagcgggtcc ctggccgctg agccgcaccg tgagcccgac gcccgtgcgg
    34561 gaagtcgata ttcccactgg gatgcgcggg gatctcgtcc cgcaccacgg tggagccgat
    34621 ggagcgcggc ccacttgacg gccccatcct tgatcggttg acgggcccgc ggttcgagcg
    34681 ggcgggtagg ggccctactc agcgtcccgg ggcgggctga ctgccaaggt ccacttgccg
    34741 ttgatggtcg ccagtgtgcg gggtgtccgg gtcgaccagg gcgagggcgc cggctccggc
    34801 cgagacgtcg cagccgcggt ggtggaaccc tcgacgccgt cggcgattgc cgcgatgacg
    34861 aagctctcgt gggtgtgccg gaggaaggtc tagcggatgt agcgggctcg cagcaggtcg
    34921 caccctg
//
