BGC0000232: hatomarubigin A biosynthetic gene cluster from Streptomyces sp. 2238-SVT4
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Location: 1 - 34,927 nt. (total: 34,927 nt).
This entry is originally from NCBI GenBank AB524586.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000232
Short description hatomarubigin A biosynthetic gene cluster from Streptomyces sp. 2238-SVT4
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide
Loci NCBI GenBank: AB524586.1
Compounds
  • hatomarubigin A
  • hatomarubigin B
  • hatomarubigin C
  • hatomarubigin D
Species Streptomyces sp. 2238-SVT4 [taxonomy]
References
Chemical products information
hatomarubigin A
Copy SMILES
C20H16O5
Chemical database entries
PubCHEM
hatomarubigin B
Copy SMILES
C20H16O5
Chemical database entries
PubCHEM
hatomarubigin C
Copy SMILES
C20H18O5
Chemical database entries
PubCHEM
hatomarubigin D
Copy SMILES
C41H36O10
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • BAJ07838.1
368 - 850 (+) putative alanine rich protein
copy AA seq
copy Nt seq
  • BAJ07839.2
  • hrbR1
1709 - 1915 (-) putative regulatory protein
copy AA seq
copy Nt seq
  • BAJ07840.1
  • hrbA
2557 - 3402 (+) hypothetical protein
copy AA seq
copy Nt seq
  • BAJ07841.1
  • hrbB
3641 - 3979 (+) putative cyclase
copy AA seq
copy Nt seq
  • BAJ07842.1
  • hrbC
3976 - 5247 (+) putative ketosynthase
copy AA seq
copy Nt seq
  • BAJ07843.1
  • hrbD
5281 - 5604 (+) hypothetical protein
copy AA seq
copy Nt seq
  • BAJ07844.1
  • hrbE
5612 - 6826 (+) putative chain length determinant factor
copy AA seq
copy Nt seq
  • BAJ07845.1
  • hrbF
6866 - 7570 (+) putative dehydrogenase-methyltransferase
copy AA seq
copy Nt seq
  • BAJ07846.1
  • hrbG
7861 - 9903 (+) putative oxygenase-reductase
copy AA seq
copy Nt seq
  • BAJ07847.1
  • hrbH
9917 - 11038 (+) putative oxygenase
copy AA seq
copy Nt seq
  • BAJ07848.1
  • hrbI
11126 - 11914 (+) putative reductase
copy AA seq
copy Nt seq
  • BAJ07849.1
  • hrbJ
11960 - 12640 (+) putative oxygenase
copy AA seq
copy Nt seq
  • BAJ07850.1
  • hrbK
12674 - 13300 (+) putative oxygenase
copy AA seq
copy Nt seq
  • BAJ07851.1
  • hrbL
13339 - 14415 (+) putative oxygenase
copy AA seq
copy Nt seq
  • BAJ07852.1
  • hrbM
14523 - 14786 (+) putative acyl carrier protein
copy AA seq
copy Nt seq
  • BAJ07853.1
  • hrbN
14789 - 15697 (+) putative hydrolase
copy AA seq
copy Nt seq
  • BAJ07854.1
  • hrbO
15732 - 16517 (+) putative ketoreductase
copy AA seq
copy Nt seq
  • BAJ07855.1
  • hrbP
16536 - 17471 (+) putative aromatase
copy AA seq
copy Nt seq
  • BAJ07856.1
  • hrbQ
17501 - 18340 (+) putative phosphopantetheinyl transferase
copy AA seq
copy Nt seq
  • BAJ07857.1
  • hrbR
18376 - 19758 (+) putative oxygenase
copy AA seq
copy Nt seq
  • BAJ07858.1
  • hrbS
19901 - 20665 (+) putative ketoacyl reductase
copy AA seq
copy Nt seq
  • BAJ07859.1
  • hrbT
20662 - 21966 (+) putative transporter
copy AA seq
copy Nt seq
  • BAJ07860.1
  • hrbU
21986 - 22990 (+) putative O-methyltransferase
copy AA seq
copy Nt seq
  • BAJ07861.1
  • hrbV
23212 - 24003 (+) putative short-chain dehydrogenase/reductase
copy AA seq
copy Nt seq
  • BAJ07862.1
  • hrbW
24125 - 24706 (+) putative reductase
copy AA seq
copy Nt seq
  • BAJ07863.1
  • hrbX
24769 - 25902 (+) putative oxygenase
copy AA seq
copy Nt seq
  • BAJ07864.1
  • hrbR2
25943 - 26545 (-) putative transcriptional regulator
copy AA seq
copy Nt seq
  • BAJ07865.1
  • hrbY
26627 - 27724 (+) putative oxidoreductase
copy AA seq
copy Nt seq
  • BAJ07866.1
  • hrbR3
27827 - 28549 (-) putative repressor-response regulator
copy AA seq
copy Nt seq
  • BAJ07867.1
  • hrbZ1
29339 - 30253 (-) putative N5,N10- methylenetetrahydromethanopterin reductase
copy AA seq
copy Nt seq
  • BAJ07868.1
  • hrbZ2
30360 - 31364 (-) putative aldo/keto reductase
copy AA seq
copy Nt seq
  • BAJ07869.1
33303 - 33464 (+) putative truncated S-adenosylmethionine synthase
copy AA seq
copy Nt seq
  • BAJ07870.1
33521 - 34531 (+) putative carbohydrate kinase
copy AA seq
copy Nt seq
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.