BGC0000234: jadomycin biosynthetic gene cluster from Streptomyces venezuelae ATCC 10712
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Location: 1 - 7,064 nt. (total: 7,064 nt).
This entry is originally from NCBI GenBank AF126429.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000234
Short description jadomycin biosynthetic gene cluster from Streptomyces venezuelae ATCC 10712
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
AF126429.1
via
Compounds
  • jadomycin
Species Streptomyces venezuelae ATCC 10712 [taxonomy]
References
Chemical products information
jadomycin Evidence:
Copy SMILES
C24H21N1O6
Chemical database entries
NPAtlas
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AAD37851.1
  • jadJ
153 - 1907 (+) JadJ
    copy AA seq
    copy Nt seq
    • AAD37852.1
    • jadI
    2020 - 2349 (+) jadomycin polyketide synthase cyclase
      copy AA seq
      copy Nt seq
      • AAB36562.1
      • jadA
      2346 - 3614 (+) jadomycin polyketide ketosynthase
        copy AA seq
        copy Nt seq
        • AAB36563.1
        3611 - 4825 (+) chain length determinant
          copy AA seq
          copy Nt seq
          • AAB36564.1
          • acp
          4868 - 5137 (+) acyl carrier protein
            copy AA seq
            copy Nt seq
            • AAB36565.1
            5211 - 6005 (+) ketoreductase
              copy AA seq
              copy Nt seq
              • AAB36566.1
              6046 - 6978 (+) bifunctional cyclase/dehydrase
                copy AA seq
                copy Nt seq
                Biosynthesis information
                Annotation changelog

                Entry version: 4

                Date
                Changes
                Submitters
                Reviewers
                Update chemical activity to schema version 2.11
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                Entry version: 3

                Date
                Changes
                Submitters
                Reviewers
                Updated bioactivity data
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                Entry version: 2

                Date
                Changes
                Submitters
                Reviewers
                Migrated from v1.4
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                Updated compound(s) information (NPAtlas curation)
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                Entry version: 1

                Date
                Changes
                Submitters
                Reviewers
                Submitted
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                Detailed domain annotation
                Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
                A domain glossary is available here, and an explanation of the visualisation is available here.
                Selected features only
                Show module domains
                Similar known gene clusters from MIBiG 4.0
                Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
                Click on reference genes to show details of similarities to genes within the current region.
                Click on an accession to open that entry in the MiBIG database.