BGC0000235: kiamycin biosynthetic gene cluster from Streptomyces sp. W007
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Location: 118,282 - 139,606 nt. (total: 21,325 nt).
This entry is originally from NCBI GenBank AGSW01000147.1.

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core biosynthetic genes
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General
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NRPS/PKS domains
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General information about the BGC
MIBiG accession BGC0000235
Short description kiamycin biosynthetic gene cluster from Streptomyces sp. W007
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide
Loci NCBI GenBank: AGSW01000147.1
Compounds
  • kiamycin
Species Streptomyces sp. W007 [taxonomy]
References
Chemical products information
kiamycin
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C20H18O4
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • SPW_4216
  • EHM27493.1
 118282 - 119031 (+) ABC transporter related protein
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  • SPW_4217
  • EHM27494.1
 119072 - 119911 (+) putative SAM-dependent methyltransferase
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  • SPW_4218
  • EHM27495.1
 120028 - 120468 (+) hypothetical protein
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  • SPW_4219
  • EHM27496.1
 120529 - 121335 (-) putative secreted hydrolase
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  • SPW_4220
  • EHM27497.1
 121832 - 122614 (-) putative short-chain dehydrogenase/reductase
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  • SPW_4221
  • EHM27498.1
 123532 - 124197 (+) two component LuxR family transcriptional regulator
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  • SPW_4222
  • EHM27499.1
 124238 - 124945 (-) putative short chain oxidoreductase
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  • SPW_4223
  • EHM27500.1
 125036 - 125704 (-) TetR family transcriptional regulator
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  • SPW_4224
  • EHM27501.1
 125908 - 127320 (+) putative export protein
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  • SPW_4225
  • EHM27502.1
 127711 - 128646 (+) O-methyltransferase family protein
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  • SPW_4226
  • EHM27503.1
 128727 - 130229 (+) monooxygenase FAD-binding
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  • SPW_4227
  • EHM27504.1
 130297 - 130596 (+) polyketide synthesis cyclase
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  • SPW_4228
  • EHM27505.1
 130593 - 131873 (+) ketoacyl synthase
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  • SPW_4229
  • EHM27506.1
 131870 - 133090 (+) chain length determinant protein
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  • SPW_4230
  • EHM27507.1
 133148 - 133417 (+) acyl carrier protein
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  • SPW_4231
  • EHM27508.1
 133470 - 134240 (+) short-chain dehydrogenase/reductase SDR
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  • SPW_4232
  • EHM27509.1
 134276 - 135247 (+) cyclase/dehydrase
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  • SPW_4233
  • EHM27510.1
 135251 - 137221 (+) monooxygenase FAD-binding
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  • SPW_4234
  • EHM27511.1
 137259 - 138023 (+) putative short chain dehydrogenase
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  • SPW_4235
  • EHM27512.1
 138029 - 139606 (+) carboxyl transferase
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Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
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