LOCUS       BGC0000235             21325 bp    DNA     linear   BCT 12-JAN-2012
DEFINITION  Streptomyces sp. W007 contig00151, whole genome shotgun sequence.
ACCESSION   BGC0000235
VERSION     BGC0000235
KEYWORDS    .
SOURCE      Streptomyces sp. W007
  ORGANISM  Streptomyces sp. W007
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
COMMENT     ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2024-10-17 13:13:52
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 118281
            Orig. end    :: 139606
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..750
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 173.5; E-value:
                     9.6e-53)"
                     /gene_kind="transport"
                     /locus_tag="SPW_4216"
                     /product="ABC transporter related protein"
                     /protein_id="EHM27493.1"
                     /transl_table=11
                     /translation="MTLLLDRVTFRYRRWERPVLSGFSYEVPDEGLTILLGPNGAGKST
                     TMSLLAGTVEPQGGKVRLKDSTLTSAARAYRRHVAWLPQKVPTSRQLTAREYVAYVAWL
                     KGEDRTGAWERAGKALDQVGLAEQSGRKTAKLSGGQLRRVGIACALAHDAQVILLDEPT
                     AGLDPHQRTVFRNVLRTVADRIPVLMSTHDIADLADEANTVSLMDRGRVLHHGATRSFL
                     DQARSDAAPGRQAESAYAVLMGLESTG"
     subregion       1..21325
                     /aStool="mibig"
                     /contig_edge="False"
                     /label="PKS"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..21325
                     /contig_edge="False"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            1..750
                     /locus_tag="SPW_4216"
     gene            791..1630
                     /locus_tag="SPW_4217"
     CDS             791..1630
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 63.4; E-value:
                     3.8e-19)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="SPW_4217"
                     /product="putative SAM-dependent methyltransferase"
                     /protein_id="EHM27494.1"
                     /transl_table=11
                     /translation="MYSPTPDDWHDTNRARWDERVPIHVASDYYELDAFLAGKDVLRAF
                     ELAEVGDVTGKSLLHLQCHFGMDTLSWARRGAAQVVGLDFSEPAVETARGLARSLELGP
                     DRASFVAADVYDAPAAVPDSAYDIVYTGIGALNWLPDLDRWAETAASLVAPGGFLYLAE
                     LHPLTDSMDETGSVVTDDYFSRDAWVDETPGTYADLDAPTAHNRSVEWQHPVGRVVTAL
                     ASAGLRIEFLHEHDSTVVQRFGTLERHADGHYRFPAGRPRIPLMYSIKASRPAEHQG"
     gene            1747..2187
                     /locus_tag="SPW_4218"
     CDS             1747..2187
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF07366"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="SPW_4218"
                     /product="hypothetical protein"
                     /protein_id="EHM27495.1"
                     /sec_met_domain="PF07366 (E-value: 4.8e-08, bitscore: 23.5,
                     seeds: 29, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPGTASSTTPGTTTAALRGAVEAYWTAAEARDWSAFGATLAEGVV
                     YDLPQTRERILGKERYLRFNQEYPGDWHVRVERIVADAEGRQAAARTGFTVTGDQPEEQ
                     PQELDAIHFFTFDEEGLITGVTDFWPESYEPPAGREHLVERY"
     gene            complement(2248..3054)
                     /locus_tag="SPW_4219"
     CDS             complement(2248..3054)
                     /codon_start=1
                     /locus_tag="SPW_4219"
                     /product="putative secreted hydrolase"
                     /protein_id="EHM27496.1"
                     /transl_table=11
                     /translation="MSVRRIRASVVTLALAAVAALGAAGPASAADSAAAGGYVALGDSY
                     SSGVGAGSYLSDSGDCRRSTNAYPYLWQAANSPASFDFVACSGATTSSVASSQLGALSA
                     STSLVSVTAGGNDVGFADVMQDCVLSGEATCINSVNNAVSQMNNSLPGSLDSLYDGIRA
                     RAPQAQVVVLGYPRFYKLAGSCFAGLSEAERSAINNASDVLNDVIAKRSADAGFTFSSV
                     VDEFTGHELCSGDAWLHSVSVPIYNSYHPKAAGQSGGYLPAFRSAV"
     gene            complement(3551..4333)
                     /locus_tag="SPW_4220"
     CDS             complement(3551..4333)
                     /NRPS_PKS="Domain: PKS_KR (1-170). E-value: 9.9e-10. Score:
                     30.4. Matches aSDomain: nrpspksdomains_SPW_4220_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     169.5; E-value: 1.5e-51)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="SPW_4220"
                     /product="putative short-chain dehydrogenase/reductase"
                     /protein_id="EHM27497.1"
                     /transl_table=11
                     /translation="MLISGAGRGIGAATAREFGRRGCHVIVNYLSNSEAAAVVVKDITS
                     AGGTAQAVRADVCDAGQVGTLVDGVLAEHGRVDVLVCNANTAAPPYGPFASLPWESFAA
                     KLTGELAGVYFLTQRVLAAMREQRAGRIVYVSSTAADVITGSIAHSTATAALNTFSRQI
                     AAEAAQYGVAANTVAPGATNTDATAFFPEAIRQYFGERSVHGRLPEPEDVGRLIALVAD
                     DGFAGATGQVFRADDGFDLLTQQLDGPAARFGGSAAQD"
     aSDomain        complement(3824..4330)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SPW_4220_PKS_KR.1"
                     /evalue="9.90E-10"
                     /label="SPW_4220_PKS_KR.1"
                     /locus_tag="SPW_4220"
                     /protein_end="170"
                     /protein_start="1"
                     /score="30.4"
                     /tool="antismash"
                     /translation="LISGAGRGIGAATAREFGRRGCHVIVNYLSNSEAAAVVVKDITSA
                     GGTAQAVRADVCDAGQVGTLVDGVLAEHGRVDVLVCNANTAAPPYGPFASLPWESFAAK
                     LTGELAGVYFLTQRVLAAMREQRAGRIVYVSSTAADVITGSIAHSTATAALNTFSRQIA
                     AEAAQY"
     CDS_motif       complement(3926..3982)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SPW_4220_0002"
                     /evalue="2.60E+00"
                     /label="PKSI-KR_m1"
                     /locus_tag="SPW_4220"
                     /protein_end="136"
                     /protein_start="117"
                     /score="0.8"
                     /tool="antismash"
                     /translation="QRVLAAMREQRAGRIVYVS"
     CDS_motif       complement(4262..4330)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SPW_4220_0001"
                     /evalue="1.50E-03"
                     /label="PKSI-KR_m1"
                     /locus_tag="SPW_4220"
                     /protein_end="24"
                     /protein_start="1"
                     /score="11.2"
                     /tool="antismash"
                     /translation="LISGAGRGIGAATAREFGRRGCH"
     gene            5251..5916
                     /locus_tag="SPW_4221"
     CDS             5251..5916
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016:LuxR family
                     DNA-binding response regulator (Score: 71.3; E-value:
                     1.1e-21)"
                     /gene_kind="regulatory"
                     /locus_tag="SPW_4221"
                     /product="two component LuxR family transcriptional
                     regulator"
                     /protein_id="EHM27498.1"
                     /transl_table=11
                     /translation="MPHISVLVAGETALLRDALTGLFHTQADICVLGQATGEHEILCRA
                     AALHPHVILVEPWADGSAVIRTVRSLRRLTPRSAVLALPARGALIDRRALEAAGVHRYL
                     PRDAGWDALLAAVRSLAPAALRNAVQRSVPALSPRETQVLRGVATAMTNQQVASSLGIT
                     TGTVKRHLHAAFRKLDAVSRLDAVTQAAAAGLIALPAPGSVGGTRTPGEAAGPRGPEG"
     gene            complement(5957..6664)
                     /locus_tag="SPW_4222"
     CDS             complement(5957..6664)
                     /NRPS_PKS="Domain: PKS_KR (2-133). E-value: 4.9e-09. Score:
                     28.2. Matches aSDomain: nrpspksdomains_SPW_4222_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     178.9; E-value: 2.1e-54)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="SPW_4222"
                     /product="putative short chain oxidoreductase"
                     /protein_id="EHM27499.1"
                     /transl_table=11
                     /translation="MTTTLITGANKGLGYETARRLTEAGHTVLLGARDPRRGRAAAERI
                     GARFLPLDVTGEESVLAAADRVREEFGHLDVLVNNAGITGPRKEAAELTADDIKKLYDT
                     NVFGAVRVTRAFLPLLRAGESPTVVNVSSGLGSLAIAAEPERFGSLLPVYYPSLGYNSS
                     KAALNMITVQYAKAFPEITFNAVDPGWTATDLNDHRGVQTVEEGAAVIVRMATLGGDGP
                     TGGFFGNTGPVPW"
     aSDomain        complement(6266..6658)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SPW_4222_PKS_KR.1"
                     /evalue="4.90E-09"
                     /label="SPW_4222_PKS_KR.1"
                     /locus_tag="SPW_4222"
                     /protein_end="133"
                     /protein_start="2"
                     /score="28.2"
                     /tool="antismash"
                     /translation="TTLITGANKGLGYETARRLTEAGHTVLLGARDPRRGRAAAERIGA
                     RFLPLDVTGEESVLAAADRVREEFGHLDVLVNNAGITGPRKEAAELTADDIKKLYDTNV
                     FGAVRVTRAFLPLLRAGESPTVVNVSS"
     CDS_motif       complement(6581..6652)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SPW_4222_0001"
                     /evalue="1.10E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="SPW_4222"
                     /protein_end="28"
                     /protein_start="4"
                     /score="14.8"
                     /tool="antismash"
                     /translation="LITGANKGLGYETARRLTEAGHTV"
     gene            complement(6755..7423)
                     /locus_tag="SPW_4223"
     CDS             complement(6755..7423)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057:TetR family
                     transcriptional regulator (Score: 108; E-value: 1.3e-32)"
                     /gene_kind="regulatory"
                     /locus_tag="SPW_4223"
                     /product="TetR family transcriptional regulator"
                     /protein_id="EHM27500.1"
                     /transl_table=11
                     /translation="MNGAKTSSASRREAPRGRIDKRQAILEAAFRTFAREGYGQSCVRE
                     IAAEAGVAKPTIYNHLGDKETLFREAMLAAVGRTSGAGLGALEQLREPDGDVRPMLEEA
                     GLRILKNHCDPESQALRWLLNAEAARFPDLLETIQREGAQRLHDALADRLARFALSGRL
                     HTSDPDLAAEQFLALLTGPMALRTRLGTRKVSDAELRAVGRAAVDTFLRAYSPRAVDSP
                     "
     gene            7627..9039
                     /locus_tag="SPW_4224"
     CDS             7627..9039
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 330; E-value:
                     3e-100)"
                     /gene_kind="transport"
                     /locus_tag="SPW_4224"
                     /product="putative export protein"
                     /protein_id="EHM27501.1"
                     /transl_table=11
                     /translation="MTLLGGIMGILDSTMVTVAADTLAAEFNTSLSSISWATTGYLLAL
                     TVTIPITSWAVGRFGVRKLWLFGLVLFLVGSLASALAWNVESLVAFRVVQGVGAGVVDP
                     LVLVILARAAGPSRAGRVMGMMGVVLSLGPVLGPVLGGVVLESMGWRWMFYINLPIGIV
                     AVLLALRVIPVGPPLKRGSGPRLDIVGALLMAPGLAAILLALTEAGERARFAVPSVLIP
                     LALGVALLVGYVIHALRARRTEPLIDIRLFSSRSFAASVTVQGLVGLATFAVLFALPLY
                     YQVLHGHGARAAGLLVAPLGLGSALAMPLAGRLSDRLGARNLVRGGAVVAALASVGLTR
                     IGADSGEVWSVLAAFAVGLGLGGVGAPTMGSLYRTLPPEKVPQGSSVVYNLNQLGGALG
                     VACVALILAAVGNGAAAGGAGIGGFHGAYWFVFAVTLVILAASPLLPGRPEAPTAVQAE
                     ASSADGSAMAHP"
     gene            9430..10365
                     /locus_tag="SPW_4225"
     CDS             9430..10365
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:O-methyltransferase (Score: 214.2; E-value:
                     4.8e-65)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="SPW_4225"
                     /product="O-methyltransferase family protein"
                     /protein_id="EHM27502.1"
                     /transl_table=11
                     /translation="MESGLFTELSGSSATAEELSTRLGYRMPGASDFFLALAGMGLLDA
                     SEAGEFRNSPAADRYLVRTRPEFIGGYLQFCERELNPAWEGLGTALRTGAPQNPAALEG
                     NPYETLYQDRESTESFLESMDTLNTPLLRRLGEIDWSGYDSFVDVGGARGNVAHHLALN
                     NPHLKGAVFDLPQLEGAFTTHMAALGDDGAVSFHGGDFFAGPLPESDVLIFGHVLHNWG
                     VDERRTLLRKAHDAIRPGGAVIIYDPMVSNSAPPLYATLAALSMLVWSAGGGEYPVSDC
                     HAWLEEAGFRPETVGPEDTPDDVLVIGRKS"
     gene            10446..11948
                     /locus_tag="SPW_4226"
     CDS             10446..11948
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050:monooxygenase FAD-binding (Score: 539.9; E-value:
                     1.1e-163)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="SPW_4226"
                     /product="monooxygenase FAD-binding"
                     /protein_id="EHM27503.1"
                     /transl_table=11
                     /translation="MDASVMVVGAGPAGLMLAGELRLAGIDVVVLDRLPQRTGESRGIG
                     LTPRTVEVLDQRGLLPRFGDIEMSSLGHFGGIPLDFGVLGGGDRAARTVPQSATESVLE
                     SWARELGADIRRDHEFTGLTDHGGHVEAQVRGPAGQQVLSCRFLVGCDGGRSAVRKAAG
                     FDFPGTPATTELLLADIRGVDLEPRMVADRVTDGMVMTARLGDGVHRVIVAERGAPPQR
                     RTGPPAFAEVADAWKRLTGIDISHAEPVWLSAFGDATRQVTEYRRGRVLLAGDSAHIHL
                     PAGGQGMNTSVQDSVNLGWKLAAVLHGAAGPALLDTYHTERHEVGRRLLANTRAQSLLI
                     LGSEEVQPLRDILTELARYEEVARHFAAKAGGLDIRYDVGSGPNPLLGMRMPRLELLRG
                     TTVTSSTELLRAGRGVLLDLADTPRLRRRAAPWADRVDLVTAAPRGTAALGGGLDGTSA
                     VLLRPDGHVAWIAPGSHHDLPMALERWFGPARQHGTAHTRAV"
     gene            12016..12315
                     /locus_tag="SPW_4227"
     CDS             12016..12315
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1225:Polyketide synthesis cyclase (Score: 138.4;
                     E-value: 1.4e-42)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="SPW_4227"
                     /product="polyketide synthesis cyclase"
                     /protein_id="EHM27504.1"
                     /transl_table=11
                     /translation="MEPGSAGEVARHFSAFDATEMPELMGTRRRELFSFRGLYFHLQDF
                     DGENGGERIEQTKGDPRFVGISQDLKPFIDAYDPATWRSPADAMARRFYHWSAE"
     gene            12312..13592
                     /locus_tag="SPW_4228"
     CDS             12312..13592
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (8-401). E-value:
                     6.8e-59. Score: 191.7. Matches aSDomain:
                     nrpspksdomains_SPW_4228_PKS_KS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T2PKS:
                     t2ks"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 494; E-value:
                     6e-150)"
                     /gene_kind="biosynthetic"
                     /locus_tag="SPW_4228"
                     /product="ketoacyl synthase"
                     /protein_id="EHM27505.1"
                     /sec_met_domain="t2ks (E-value: 3.9e-245, bitscore: 803.9,
                     seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAVYGRQVVITGIGVTAPGGPGTKGFWQLLTDGRTATRRISFFD
                     PSPFRSQVAAEVDFDAEACGLGPQEIRRMDRAAQLAVVTAREAAADSGLAFHTLDPGRM
                     GVTIGSAVGATMGLDEEYRTVSDGGRRELVDHEYAVPHLYNYMVPSSFAAEVAHAMGAE
                     GPASVVSTGCTSGLDAVGYATEVIREGTADVMIAGATEAPISPITVACFDAIKATTPRN
                     DDPAHASRPFDASRNGFVLGEGAAVFVLEDGESARRRGAHVYAEVAGYATRSNAFHMTG
                     LRPDGKEMAEAIRIAIAEARVNPEDIDYINAHGSGTKQNDRHETAAFKLSLGEAAYRTP
                     VSSIKSMVGHSLGAVGSIELAASALAMEHHVIPPTANLHTPDPECDLDYTPLTARERRT
                     DTVLSVGSGFGGFQSAVVLARPDRRRR"
     aSDomain        12336..13514
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SPW_4228_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="6.80E-59"
                     /label="SPW_4228_PKS_KS.1"
                     /locus_tag="SPW_4228"
                     /protein_end="401"
                     /protein_start="8"
                     /score="191.7"
                     /tool="antismash"
                     /translation="VVITGIGVTAPGGPGTKGFWQLLTDGRTATRRISFFDPSPFRSQV
                     AAEVDFDAEACGLGPQEIRRMDRAAQLAVVTAREAAADSGLAFHTLDPGRMGVTIGSAV
                     GATMGLDEEYRTVSDGGRRELVDHEYAVPHLYNYMVPSSFAAEVAHAMGAEGPASVVST
                     GCTSGLDAVGYATEVIREGTADVMIAGATEAPISPITVACFDAIKATTPRNDDPAHASR
                     PFDASRNGFVLGEGAAVFVLEDGESARRRGAHVYAEVAGYATRSNAFHMTGLRPDGKEM
                     AEAIRIAIAEARVNPEDIDYINAHGSGTKQNDRHETAAFKLSLGEAAYRTPVSSIKSMV
                     GHSLGAVGSIELAASALAMEHHVIPPTANLHTPDPECDLDYTPLTARERRTDT"
     CDS_motif       12486..12521
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SPW_4228_0001"
                     /evalue="7.00E+00"
                     /label="PKSI-KS_m4"
                     /locus_tag="SPW_4228"
                     /protein_end="70"
                     /protein_start="58"
                     /score="1.0"
                     /tool="antismash"
                     /translation="FDAEACGLGPQE"
     CDS_motif       13005..13043
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SPW_4228_0002"
                     /evalue="2.70E-02"
                     /label="PKSI-KS_m4"
                     /locus_tag="SPW_4228"
                     /protein_end="244"
                     /protein_start="231"
                     /score="8.1"
                     /tool="antismash"
                     /translation="FDASRNGFVLGEG"
     gene            13589..14809
                     /locus_tag="SPW_4229"
     CDS             13589..14809
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (66-402). E-value:
                     9.8e-27. Score: 85.7. Matches aSDomain:
                     nrpspksdomains_SPW_4229_PKS_KS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T2PKS:
                     t2clf"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093:Beta-ketoacyl synthase (Score: 667.2; E-value:
                     1.2e-202)"
                     /gene_kind="biosynthetic"
                     /locus_tag="SPW_4229"
                     /product="chain length determinant protein"
                     /protein_id="EHM27506.1"
                     /sec_met_domain="t2clf (E-value: 5.2e-211, bitscore: 690.9,
                     seeds: 26, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNATTVVTGLGVAAPNGLGLESYWSAVLAGRGAIGRVGRFDPTSY
                     PAQLAGEIAGFTAEDHLPSRLLPQTDRMTRLALVSADWALEDAGVVPDTLPAYDMGVIT
                     ASHSGGFEFGQKELRALWSKGGRYVSAYQSFAWFYAVNSGQISIRNGMRGPSGVVVSDQ
                     AGGLDALAQARRQIRKGTPLIVSGAIDASICPWGWVAQLASGRLSRATDPGRAYVPFDD
                     GAAGHVPGEGGALLILEDADHARARGARQVYAEIAGHASTFDPAPGGDRGPGLRRAVEQ
                     ALCDGETAPGDVDVVFADAAAVPELDRVEAEAISKVFGPRAVPVTAPKTMTGRLYSGAA
                     PLDVATACLSIRDGVIPPTTNTSLSPHYDIDLVTGPPRETPVRTALVLARGYGGFNSAV
                     VVRAPRD"
     aSDomain        13787..14794
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SPW_4229_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="9.80E-27"
                     /label="SPW_4229_PKS_KS.1"
                     /locus_tag="SPW_4229"
                     /protein_end="402"
                     /protein_start="66"
                     /score="85.7"
                     /tool="antismash"
                     /translation="LPQTDRMTRLALVSADWALEDAGVVPDTLPAYDMGVITASHSGGF
                     EFGQKELRALWSKGGRYVSAYQSFAWFYAVNSGQISIRNGMRGPSGVVVSDQAGGLDAL
                     AQARRQIRKGTPLIVSGAIDASICPWGWVAQLASGRLSRATDPGRAYVPFDDGAAGHVP
                     GEGGALLILEDADHARARGARQVYAEIAGHASTFDPAPGGDRGPGLRRAVEQALCDGET
                     APGDVDVVFADAAAVPELDRVEAEAISKVFGPRAVPVTAPKTMTGRLYSGAAPLDVATA
                     CLSIRDGVIPPTTNTSLSPHYDIDLVTGPPRETPVRTALVLARGYGGFNSAVVVR"
     gene            14867..15136
                     /locus_tag="SPW_4230"
     CDS             14867..15136
                     /NRPS_PKS="Domain: ACP (13-83). E-value: 1.3e-17. Score:
                     55.7. Matches aSDomain: nrpspksdomains_SPW_4230_ACP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1129:acyl carrier protein (Score: 119.6; E-value:
                     7.5e-37)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="SPW_4230"
                     /product="acyl carrier protein"
                     /protein_id="EHM27507.1"
                     /sec_met_domain="PP-binding (E-value: 1.4e-12, bitscore:
                     38.5, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPATPFTIDDLKSILREGAGADEGVDLDGDILDAEFDALGYESLA
                     MLETAGRIEREYGISLDEEIFADARTPRALIALVNGQLPSAQAV"
     aSDomain        14906..15115
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SPW_4230_ACP.1"
                     /evalue="1.30E-17"
                     /label="SPW_4230_ACP.1"
                     /locus_tag="SPW_4230"
                     /protein_end="83"
                     /protein_start="13"
                     /score="55.7"
                     /tool="antismash"
                     /translation="ILREGAGADEGVDLDGDILDAEFDALGYESLAMLETAGRIEREYG
                     ISLDEEIFADARTPRALIALVNGQL"
     gene            15189..15959
                     /locus_tag="SPW_4231"
     CDS             15189..15959
                     /NRPS_PKS="Domain: PKS_KR (2-160). E-value: 2.5e-11. Score:
                     35.6. Matches aSDomain: nrpspksdomains_SPW_4231_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     253.6; E-value: 3.2e-77)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="SPW_4231"
                     /product="short-chain dehydrogenase/reductase SDR"
                     /protein_id="EHM27508.1"
                     /sec_met_domain="adh_short (E-value: 6e-38, bitscore:
                     121.1, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVALVTGATSGIGLATTRLLAGQGHKVFLCARTEDDVSRTVKEL
                     RGEGLEVDGRAADVCSKDDIRDLVRAAVGRFGPIDILVNNAGRSGGGVTADIADELWFD
                     VINTNLNSVFLVTREVLTTGGMRDRPGGRVINIASTAGKQGVVLGAPYSASKHGVVGFT
                     KALGNELAPTGITVNAVCPGYVETPMAQRVRQGYAAAYEVDEEQILEKFTAKIPLGRYS
                     TAEEVAGLVGYLTSDTAASITAQALNVCGGLGNF"
     aSDomain        15195..15668
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SPW_4231_PKS_KR.1"
                     /evalue="2.50E-11"
                     /label="SPW_4231_PKS_KR.1"
                     /locus_tag="SPW_4231"
                     /protein_end="160"
                     /protein_start="2"
                     /score="35.6"
                     /tool="antismash"
                     /translation="VALVTGATSGIGLATTRLLAGQGHKVFLCARTEDDVSRTVKELRG
                     EGLEVDGRAADVCSKDDIRDLVRAAVGRFGPIDILVNNAGRSGGGVTADIADELWFDVI
                     NTNLNSVFLVTREVLTTGGMRDRPGGRVINIASTAGKQGVVLGAPYSASKHGVV"
     CDS_motif       15201..15269
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SPW_4231_0001"
                     /evalue="1.30E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="SPW_4231"
                     /protein_end="27"
                     /protein_start="4"
                     /score="17.8"
                     /tool="antismash"
                     /translation="LVTGATSGIGLATTRLLAGQGHK"
     gene            15995..16966
                     /locus_tag="SPW_4232"
     CDS             15995..16966
                     /NRPS_PKS="Domain: Polyketide_cyc2 (16-157). E-value:
                     6.3e-17. Score: 54.1. Matches aSDomain:
                     nrpspksdomains_SPW_4232_Polyketide_cyc2.1"
                     /NRPS_PKS="Domain: Polyketide_cyc2 (166-320). E-value:
                     2.9e-10. Score: 32.5. Matches aSDomain:
                     nrpspksdomains_SPW_4232_Polyketide_cyc2.2"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1128:cyclase/dehydrase (Score: 457.9; E-value:
                     2.8e-139)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="SPW_4232"
                     /product="cyclase/dehydrase"
                     /protein_id="EHM27509.1"
                     /transl_table=11
                     /translation="MPTTAKEMNMTEQAPREVEHEITVSAPAPEVYRLLAEVENWPRIF
                     PPSVYVDYVEKNGDEERIRIWATANGEAKNWTSRRRLDPAGLRITFGQEVSAPPVAEMS
                     GTWIIEPQGAGCRLRLLHSYRAIDDDPAGLAWIDRAVDRNSRSELAALKTNVELAAHSA
                     ELTLTFEDSVRINGSAKDAYDFVNEAQLWTDRLPHVSRVSLTEDEPGVQTLRMDTVAKD
                     GSTHTTESVRVCFPHHGIVYKQTTLPALMTLHTGSWRFDEGSDGVTTATSRHTVVINTE
                     NIMRILGPDAGIPQARTFLREALGANSRATLGHAKSYAEARR"
     aSDomain        16043..16465
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SPW_4232_Polyketide_cyc2.1"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="6.30E-17"
                     /label="SPW_4232_Polyketide_cyc2.1"
                     /locus_tag="SPW_4232"
                     /protein_end="157"
                     /protein_start="16"
                     /score="54.1"
                     /tool="antismash"
                     /translation="EVEHEITVSAPAPEVYRLLAEVENWPRIFPPSVYVDYVEKNGDEE
                     RIRIWATANGEAKNWTSRRRLDPAGLRITFGQEVSAPPVAEMSGTWIIEPQGAGCRLRL
                     LHSYRAIDDDPAGLAWIDRAVDRNSRSELAALKTNVE"
     aSModule        16043..16954
                     /domains="nrpspksdomains_SPW_4232_Polyketide_cyc2.1"
                     /domains="nrpspksdomains_SPW_4232_Polyketide_cyc2.2"
                     /incomplete
                     /locus_tags="SPW_4232"
                     /tool="antismash"
                     /type="unknown"
     aSDomain        16493..16954
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SPW_4232_Polyketide_cyc2.2"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="2.90E-10"
                     /label="SPW_4232_Polyketide_cyc2.2"
                     /locus_tag="SPW_4232"
                     /protein_end="320"
                     /protein_start="166"
                     /score="32.5"
                     /tool="antismash"
                     /translation="LTFEDSVRINGSAKDAYDFVNEAQLWTDRLPHVSRVSLTEDEPGV
                     QTLRMDTVAKDGSTHTTESVRVCFPHHGIVYKQTTLPALMTLHTGSWRFDEGSDGVTTA
                     TSRHTVVINTENIMRILGPDAGIPQARTFLREALGANSRATLGHAKSYAE"
     gene            16970..18940
                     /locus_tag="SPW_4233"
     CDS             16970..18940
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050:monooxygenase FAD-binding (Score: 418.9; E-value:
                     5.3e-127)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="SPW_4233"
                     /product="monooxygenase FAD-binding"
                     /protein_id="EHM27510.1"
                     /transl_table=11
                     /translation="MGGSADADVLVVGAGPVGLLLAGEVSAGGARTVVLEQLAGPTAES
                     RASILHTRTMEILAERGILDRLGDLPAGGRGHFGGIPFDLAEADPGHPYAGQWECLQSR
                     LEPVLEAWAVERGAEVRRGHVVTGLTQHDDRVEVVAFGPGGRSHRLTAAYVVGCDGEQS
                     TVRRLAGFAMTGDDATREMLRADVLGIDIPGRRLRRYADGTATAHRRGDGTTRLMVHDR
                     TRAPGPRTREPEFAEVAAAWARVTGEDISGGTAVWLNSFDDTRRQARDYRRGRVLLAGD
                     AAHVQMPVGGQALNLGLQDAAGLGRRLAARITGGTGDGGLDEYHTERHAAGTRTLTNIQ
                     AQALLLFGGPEVDGIREVCGELLGMDVVRRHLARTISGLDRPAPPPAADTTPPLSAHGS
                     PTMDRLTGKTALVTGSSRGIGRATAVRLAREGALVAVHYATNDEAALETVALIEKEGGR
                     AFPVRAELGVPGDVHELFFGLEQGLKERTGETALDIVVNNAAVTGSDGISPEDVTPEQL
                     DRYFAVNARAPYLVIQRALRNMPDGGRVINISTALTRTAVPEQVAYAMTKGAIEQISLH
                     LAKHLAPRGITVNSVAPGITDNGGPVFDIPEAVEQMAQVSAFKRVGDAGDVADVVTFLA
                     TDEARWITGSFIDASGGTLLG"
     gene            18978..19742
                     /locus_tag="SPW_4234"
     CDS             18978..19742
                     /NRPS_PKS="Domain: PKS_KR (8-151). E-value: 1.3e-09. Score:
                     30.1. Matches aSDomain: nrpspksdomains_SPW_4234_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     183.8; E-value: 6.7e-56)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="SPW_4234"
                     /product="putative short chain dehydrogenase"
                     /protein_id="EHM27511.1"
                     /transl_table=11
                     /translation="MTSDSPRITLVTGANKGIGRAVVRRLGELGQRVYLGARDVERGRN
                     AERELRAEGLDVRFVQLDVTDESSVALAAKRIEEETGHLDALVNNAGTGAPVRAPSRTP
                     ASVVRRTYETNVFGVITVINTMLPLLRRSRAARIVNVSSVVGSLTHAAALDDPTGEFPK
                     GTYPAVLDYGTSKAALNAVTITYANELRPERILVNAVSPGFCSTDINGHQGHLTPEQGA
                     RIPVLLATLGDDGPTAVFLGEDGSPTGQRLAW"
     aSDomain        19002..19430
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SPW_4234_PKS_KR.1"
                     /evalue="1.30E-09"
                     /label="SPW_4234_PKS_KR.1"
                     /locus_tag="SPW_4234"
                     /protein_end="151"
                     /protein_start="8"
                     /score="30.1"
                     /tool="antismash"
                     /translation="TLVTGANKGIGRAVVRRLGELGQRVYLGARDVERGRNAERELRAE
                     GLDVRFVQLDVTDESSVALAAKRIEEETGHLDALVNNAGTGAPVRAPSRTPASVVRRTY
                     ETNVFGVITVINTMLPLLRRSRAARIVNVSSVVGSLTHA"
     CDS_motif       19005..19073
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SPW_4234_0001"
                     /evalue="2.90E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="SPW_4234"
                     /protein_end="32"
                     /protein_start="9"
                     /score="13.5"
                     /tool="antismash"
                     /translation="LVTGANKGIGRAVVRRLGELGQR"
     gene            19748..21325
                     /locus_tag="SPW_4235"
     CDS             19748..21325
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059:acetyl-CoA carboxylase, carboxyl transferase,
                     (Score: 708.3; E-value: 1.1e-214)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="SPW_4235"
                     /product="carboxyl transferase"
                     /protein_id="EHM27512.1"
                     /transl_table=11
                     /translation="MVRVDGPSEPTDLDDLGELGERKRLAEQGPDPRATERQHAKGKLT
                     ARERIALLLDKGSFTEVEALRRHRASGFGLEAKRPYTDGVVTGWGTVEGRTVFVYAHDF
                     RIFGGALGEAHAQKIHKIMDLAVAAGAPLVSLNDGAGARIQEGVSALAGYGGIFSRNTR
                     ASGVIPQISVMLGPCAGGAAYSPALTDFVFAVRGISQMFITGPDVVQAVTGEEISQDGL
                     GGADVHAGVSGVAHFVYDDEETCLAEVRFLLCLLPANNRELPPVAPGVDRADRLCDALP
                     GLVPDEAGHSYDIRAVIEELVDEGEHMEVHAVWAPNLVCSLARLDGQVVGIVANQPAAM
                     AGVLDITASEKGARFVQFCDAFNIPLVTLVDVPGFLPGVRQEHEGIIRRGAKLLYAYCN
                     ATVPRISVVLRKAYGGAYIVMDSRSIGADIALAWPGNEIAVMGAEGAANVVFRREIAAA
                     EDPEETRRQKIEDYKRELVHPFYAAERGLVDDVIDPRETRSVLIRSLSMLRTKDSGLPR
                     RKHGNPPQ"
ORIGIN
        1 atgaccctgc tgctcgaccg cgtcaccttc cgctaccgcc gctgggaacg ccccgtcctc
       61 tccggcttca gctacgaggt ccccgacgag ggcctgacga tcctgctcgg ccccaacgga
      121 gcgggcaagt cgaccacgat gtccctcctg gcgggcacgg tggagcccca gggtggcaag
      181 gtccggctca aggactccac tctcacctcc gccgcccgcg cgtaccgccg gcatgtggcg
      241 tggctgccgc agaaggtacc gacgtcacgg cagctgaccg cccgcgagta cgtggcgtac
      301 gtggcctggc tgaagggcga ggaccgtacg ggagcctggg agcgcgctgg gaaggccctc
      361 gaccaggtgg gcctcgccga gcagagcggc cggaagacgg ccaagctctc cggaggccag
      421 ctccgtcggg tcggcatcgc gtgcgcgctg gcccacgacg cgcaggtgat cctcctcgac
      481 gagcccacgg ccggactcga cccgcaccag cgcaccgtct tccgaaacgt gctgcgcacg
      541 gtcgccgacc gcattccggt cttgatgtcc acccacgaca tcgccgacct ggccgacgag
      601 gcgaacaccg tctccctcat ggaccgcggc cgggtcctcc accacggagc gacccggagc
      661 ttcctggacc aggcgcggtc cgacgccgct cctggccggc aggccgagtc cgcgtacgcc
      721 gtcctcatgg gtctggagag caccggataa ccactcgcac gcctcccggc ccgcggatag
      781 ctttccggac atgtactccc cgactcctga cgactggcac gacaccaacc gcgcgcgctg
      841 ggacgaacgc gtgccgatcc acgtggcgag cgactactac gagctggacg cgttcctggc
      901 gggcaaggac gtgctgcgcg ccttcgaact ggccgaggtc ggcgacgtca ccggcaagag
      961 cctgctgcac ctccagtgcc atttcggcat ggacaccctc tcctgggcac ggcgcggcgc
     1021 cgcacaggtc gtgggtctcg acttctccga gcccgccgtc gagaccgccc ggggcctggc
     1081 caggtcactg gagctgggcc cggaccgggc gtcgttcgtc gcggccgacg tgtacgacgc
     1141 accggccgcc gtccccgact ccgcgtacga catcgtctac acgggcatcg gcgcgctgaa
     1201 ctggctgccc gacctcgacc gctgggccga gaccgccgcc tcgctggtcg cccccggcgg
     1261 attcctctac ctcgcggagc tccatccgct gaccgactcg atggacgaga ccggttcggt
     1321 cgtcaccgac gactacttca gccgcgacgc ctgggtggac gagacgccgg gcacgtacgc
     1381 cgacctggac gcgccgaccg cgcacaaccg cagcgtggag tggcagcacc cggtgggccg
     1441 ggtggtgacg gcgctcgcct cggccggcct gcggatcgag ttcctccacg agcacgactc
     1501 cacggtcgtc cagcggttcg gcacgctgga gcgccacgcg gacggccact accgtttccc
     1561 ggcgggccgc ccgaggattc cgctgatgta ctcgatcaag gcgtcgcgcc ccgcggagca
     1621 tcagggatag ccgcccctcc gggcttctcc ggccgattgt cagtggcggg gtacacactc
     1681 gtttccatga ccgacacgac aggcgtaacg gcgggcggag ccacgcccgg tacgacttcc
     1741 agcaccatgc ccgggacggc ttccagcacc acgcccggga cgacgacggc agcgctgcgc
     1801 ggcgcggtcg aggcgtactg gacggcggcc gaggcgcgcg actggagcgc gttcggtgcg
     1861 accctcgccg agggcgtggt gtacgacctg ccgcagacgc gggagcggat cctcggcaag
     1921 gagcggtatc tccggttcaa ccaggagtat ccgggcgact ggcacgtccg ggtcgagcgg
     1981 atcgtcgccg acgccgaggg ccggcaggcc gccgcccgta ccggcttcac cgtgacgggc
     2041 gatcagccgg aggagcagcc gcaggagttg gacgccatcc acttcttcac gttcgacgag
     2101 gaggggctga tcaccggggt gacggacttc tggcccgagt cgtacgagcc tccggccggc
     2161 cgcgagcacc tggtcgagcg ctactgagaa cggcggccca ccggtcaccc ggtgaaccgc
     2221 cgttccgtga gcggagacgc gcagcggcta cacggccgag cggaaggcgg gcagatagcc
     2281 gcccgactgc cccgcggcct tggggtgata cgagttgtag atcggcaccg atacgctgtg
     2341 gagccaggcg tcgccggagc acagctcgtg cccggtgaac tcgtcgacca cgctggagaa
     2401 ggtgaacccg gcgtcggcgg accgcttggc gatgacgtcg ttcagaacgt ccgacgcgtt
     2461 gttgatcgcg gaccgttcgg cctcactgag accggcgaag cagctgccgg ccagcttgta
     2521 gaagcgcggg tagccgagaa ccacgacctg ggcctgcggc gcgcgggccc ggatgccgtc
     2581 gtagagcgaa tcgaggctgc cgggcaggga gttgttcatt tgcgagacgg cgttgttcac
     2641 gctgttgatg caggtggcct cgcccgacag cacgcagtcc tgcatgacgt cggcgaaccc
     2701 gacgtcattg cctccggcgg tgacgctgac cagggaggtg gacgcgctga gcgccccgag
     2761 ctggctgctg gccacggacg aggtggtcgc tcccgaacag gcgacgaagt cgaacgaggc
     2821 gggggagttg gccgcctgcc acagatacgg gtaggcgttg gtgctgcgcc ggcagtcgcc
     2881 gctgtcggaa aggtagcttc cggcgccgac gcccgaggag taggagtcgc cgagcgcgac
     2941 atagccgccc gcggcggccg agtcggccgc ggaggccggc cccgcggcgc cgagcgcggc
     3001 cacggcggcg agcgcgagag tgacgacgga tgcacgaatt ctgcgtactg acatggctgc
     3061 cagcccttcg aagtgtgggg ggatgagggg ttggagaacg cactgtgggt gccaggtggg
     3121 ggagagggag cgatggagtt tctagcagct accggtaccc gccggtaatg cccgcgcgag
     3181 aagtcgtctg atatgcccga atgatcgttc ggtgagccat gctccgcgcg tagataaacg
     3241 ctcaactgct ggccgaaacc tgcaagttca agagggccct gcgcctcccg gaggggcggg
     3301 gcgagcggcg gcgcgcggcg cgggagagcc ctgtccgggt cccggagcgc gggcgatttc
     3361 atccggacgg gtgaggcggc cgacgcgggg ccccgcaggg ccgtcggctt gtgtcatgcc
     3421 gtcaggtggc cgcaggcgcg gaagcgtcgg cgtggaagat cgccggacgg acgcgagcgc
     3481 ccagccggtg ctggggcggc gtccgtccgg cttcgcggcg gagcgggtaa ggacctcggc
     3541 cggggtcccg tcagtcctgg gcggcggagc cgccgaaccg ggctgccggg ccgtcgagtt
     3601 gctgggtgag cagatcgaag ccgtcgtcgg cccggaacac ctgaccggtc gccccggcga
     3661 acccgtcgtc ggcgaccagg gcgatcagcc ggccgacatc ctcgggttcg ggcagcctgc
     3721 cgtgcacgga gcgctcaccg aagtactgcc gaatggcctc ggggaagaag gccgtggcat
     3781 cggtgttggt cgcgcccggg gcgacggtgt tggccgcgac cccgtactgg gcggcctcgg
     3841 cggcgatctg ccggctgaac gtgttgagcg ccgcggtggc ggtggaatgg gcgatgcttc
     3901 cggtgatcac atcggcggcg gtgctcgaca cgtagacgat ccggcccgcg cgctgctccc
     3961 gcatggccgc cagtacccgc tgcgtcagga agtagacgcc ggccagctcc ccggtgagct
     4021 tggcggcgaa ggactcccag ggcagcgagg cgaacggacc gtacggcggc gcggcggtat
     4081 tggcgttgca caccagcaca tcgacccgtc cgtgctccgc cagcactccg tcgaccagtg
     4141 tgccgacctg gcccgcgtca cagacatcgg cgcgtacggc ctgcgcggtg ccgcccgcgg
     4201 acgtgatgtc cttgaccacg accgcggcgg cttcgctatt gctcagatag ttgacgatca
     4261 catggcagcc acgtcgcccg aattcacgtg cggtcgcggc tccgatgcct cggccggctc
     4321 cactgatcag cacaattcgc cgtgtgttgg tcatttgcat ctccagaaca tcgtcaacga
     4381 ctggacctgc ccggggaata acgcatcgcg tattcaaccc agctgtgggc acagccgatt
     4441 ctggcagagc cgctgagcgc ccggcagccg cggctcttcg aaatctgcgt gaagattgac
     4501 agcgtcgggc cggacgaccg gagcgaggga gagcaggtgt ggtcgatctc acaatgggcg
     4561 acatcacgtc agactgtcct aattcgaagg gtcctttcat gtggagaacg ttcgtaccga
     4621 gagagtgcgg gcgtctcata taagacccga tcagggctcc cctggtgagc ggctccggaa
     4681 cggacattcg ggcgatccca tcgatcctgc ccattcacgc catgcttcga cgggccccgg
     4741 tcgccgtcct ctcgggccgg ggccgcagaa cccggacact ctcaggtgtc aattctcgcc
     4801 tgtttgcgtc aatcgccttc tccgtcgtcg gatttgtggc acggctccgg gcgggcggtg
     4861 tgggggtggc cgggtagtgc ggcgacgata tgaaggcagt tgccaaagtc atccgcggcg
     4921 gtaaaattcc agcgcgttcc gctattcgca tatctgccta gatgtacgcg ccgaccaggg
     4981 gggcgacgtg ctcgcgcacc acgacgcccc gcagtcggag ttcgcgccgc gggggtcgaa
     5041 gggtccaccc gtcggctctt caccgctccg ctggatatcc ggcgatgtca gtgccacacg
     5101 ggtgcgaccc ggcacctcgc gcctcccggg tgagatgtcc gcaccaagca tgggcccacg
     5161 actgcctacc caacagccgt gtcgctactt cgcacctcga tgtcagtcag caccccgtga
     5221 gccgggtgtc caacctgccg aaggggaacc atgcctcata tctccgtcct cgtcgccggc
     5281 gagaccgctt tactgcgcga cgcactgaca gggctgttcc acacccaggc cgatatctgt
     5341 gtcctcggcc aggccaccgg cgaacacgag atcctgtgca gggcagcggc cctgcacccc
     5401 catgtgatcc tcgtggagcc atgggcggac gggagcgccg tcatccgcac cgtccgctcg
     5461 ctgcgccgcc tcaccccgag atcggccgtg ctcgcgctgc cggcgcgcgg cgcgctgatc
     5521 gaccggcgcg ccctggaggc ggcgggggtg cacagatacc tgccgcggga cgcgggctgg
     5581 gacgccctgc tcgcggcggt acgctcgctc gctcccgcgg ccttgcggaa cgccgtccag
     5641 cggtcggtcc ccgcgctctc gccccgcgag acgcaggtgc tgcgtggagt ggccaccgcc
     5701 atgaccaacc agcaggtggc cagcagcctg ggcatcacga ccggtaccgt caaacggcat
     5761 ctgcacgcgg ccttccgcaa actggacgcc gtctcccggc tcgacgcggt gacccaggcc
     5821 gcggcggccg gtctcatcgc cctgccggcg cccggatcgg tgggtggaac gcggacgccc
     5881 ggtgaagccg ccggtccacg aggcccggag gggtgaccgc accgggaccg acggcgcggc
     5941 tgccggggca ccggagtcac caggggacgg ggccggtgtt cccgaagaag ccgccggtgg
     6001 ggccgtcgcc tccgagcgtg gccatccgga cgatcaccgc ggcgccctcc tcgacggtct
     6061 ggacgccccg gtggtcgttc aggtcggtgg cggtccagcc cgggtccacg gcgttgaacg
     6121 tgatctccgg gaaggccttc gcgtactgca cggtgatcat gttcagggcg gccttggagg
     6181 agttgtagcc caggctcggg tagtacacgg gaagcagcga cccgaagcgc tcgggctcgg
     6241 cggcgatggc cagtgatccc agtccgctgc tgacgttcac cacggtgggc gactcaccgg
     6301 cccggagcag tggcaggaac gcgcgggtga cccggacggc tccgaacaca ttggtgtcgt
     6361 agagcttctt gatgtcgtcg gccgtcagct ccgcggcctc cttgcggggg ccggtgattc
     6421 cggcgttgtt gacgaggacg tccaggtgcc cgaactcctc acggacgcga tcggctgccg
     6481 ccaggacgga ctcctcgccg gtcacgtcga gcgggagaaa acgggcgccg atccgctcgg
     6541 ccgccgctcg cccgcgccgg gggtcgcgtg ccccgaggag gacggtgtgg cccgcctcgg
     6601 tcaggcgtcg ggcggtctcg tatccgaggc ccttgttggc gccggtgatc agtgtcgtgg
     6661 tcatggcccg cctctcgtgc tctgctctgc gccccttctc cgtgcccttt tccgtgccgc
     6721 ttctccgggc ccctgccctg gtcgtcctgg gcgtctacgg agagtccacg gcccggggag
     6781 agtaggcgcg caggaacgtg tcgaccgcgg cccgccccac ggcacgcagt tcggcgtcgg
     6841 acaccttgcg cgtaccgagc cgggtgcgca gcgccatcgg gcccgtgagc agcgcgagga
     6901 actgctcggc ggccaggtcc gggtcgctgg tgtgcaggcg cccggagagc gcgaagcgtg
     6961 ccaggcggtc ggcgagcgcg tcgtggaggc gctgcgcgcc ctcgcgctgg atggtctcca
     7021 acaggtcggg aaaccgcgcc gcttcggcgt tgaggagcca gcgcagcgcc tgcgactccg
     7081 ggtcgcagtg gttcttcaga atgcggaggc cggcttcctc cagcatgggg cgcacatcac
     7141 cgtcaggctc ccggagctgt tcgagcgccc cgagccccgc gccgctcgta cggccgacgg
     7201 cggccagcat cgcctcgcgg aacagcgtct ccttgtcccc gaggtggttg tagatggtgg
     7261 gcttggccac gcccgcctcg gccgcgatct cccgtacgca ggactgtccg tacccctcac
     7321 gggcgaacgt cctgaacgcg gcttcgagga tcgcctgccg cttgtcgatg cgcccgcgcg
     7381 gcgcctcgcg tctgctcgcg cttgaggtct tggctccgtt cacgccgcca tcgtaccgcg
     7441 tcaacctcat atatgaaccg ggcggttcaa ctttctgggc gagttggttg caggaggtca
     7501 tggcgggtcg ttatattgaa ccgcctggtt caacaagtgt tcgtgtgtcg ctcttaacgg
     7561 agttggaaag tgatgtctca agtcagagat gaccggctgg atcccgggct gttacggctc
     7621 atcggggtga ccctgctggg cgggatcatg gggatcctcg acagcacgat ggtcaccgtc
     7681 gcggccgaca ccctcgcggc ggagttcaac acctcgctga gttccatcag ttgggccacg
     7741 accggctatc tgctggcgct cacggtcacc atccccatca cgagctgggc ggtgggccgg
     7801 ttcggcgtca ggaagctctg gcttttcgga ctggtgctgt tcctggtcgg ttcgctcgcc
     7861 tccgccctcg cctggaacgt ggagagcctg gtcgccttcc gggtcgtcca gggtgtgggc
     7921 gccggtgtcg tcgacccgct ggtcctggtg atcctggccc gtgcggcggg ccccagccgg
     7981 gcggggcgcg tgatgggcat gatgggcgtg gtcctgtcgc tcgggccggt cctcgggccc
     8041 gtgctgggcg gggtcgtgct cgaatccatg ggctggcgct ggatgttcta catcaacctg
     8101 cccatcggga tcgtcgcggt cctgctcgcg ctgcgggtga tcccggtcgg cccgcccctc
     8161 aagcgcgggt ccgggccccg tctcgacatc gtcggcgccc tgttgatggc tcccggtctc
     8221 gcggcgatcc tgctcgccct cacggaggcg ggcgagcgcg cccggttcgc cgtgccctcc
     8281 gtgctcatcc cgctggccct gggcgtcgcg ctgctcgtcg ggtacgtgat ccacgcgctg
     8341 cgagcccgcc gcaccgaacc gctgatcgac atccggctgt tcagcagccg cagcttcgcc
     8401 gcgagcgtga ccgtgcaggg gctcgtcgga ctggccacgt tcgccgtcct gttcgccctg
     8461 ccgctctact atcaggtgct gcacggacac ggcgcccgcg cggccggact gctggtggcg
     8521 ccgctgggcc tgggatcggc gctcgccatg cctctcgccg gccgcctcag cgaccggctg
     8581 ggagcgcgca atctcgtacg cggcggagcg gtcgtggcgg cgctcgcctc ggtcggcctc
     8641 acccgtatcg gtgcggacag cggtgaagtc tggtccgtgc tggccgcgtt cgccgtcggc
     8701 ctgggcctgg gcggcgtcgg cgcgccgacc atgggttcgc tgtaccggac gctgccgccg
     8761 gagaaggtgc cgcagggcag ttccgtcgtc tacaacctca accagttggg cggcgcgctc
     8821 ggggtcgcgt gtgtcgccct gatcctggcg gccgtcggaa atggcgccgc ggccggcggc
     8881 gccgggatcg gtggcttcca cggtgcgtac tggttcgttt tcgcggtcac cctggtgatt
     8941 ctggccgcct ctccgctgct gcccggccgc cccgaggccc cgaccgcggt gcaggccgag
     9001 gcgtcgtccg ccgacggctc cgccatggcg cacccatagc ggcctgcggg tgaagaatcg
     9061 gaactgagaa cgcgcagccg aaaacgcggt agtgaaggcc gggtccgcac catgtgcggg
     9121 cccggccttc agcgcgcccg cgccctcttg cacgccttcg tttccggctg attgcattct
     9181 gctcatttcc gtaattctgc gttcactttg agcggctttt ggtcgtttct tggacggccg
     9241 ctgcgaggat ccacaggact cggcaaccga accacgatcc gttcggattc ggagtcgtcc
     9301 tgctactcct tggaggggcc tcgtatgagc gaccagaaga atgcggttcc ggagccggaa
     9361 gagccattta tcggtcaggt catgggaccg ttgaccggat tctggcagac gaagattctg
     9421 cttaccgccg tggaatccgg tctcttcacc gaattgtccg gttcctcggc caccgccgag
     9481 gaactgagca ctcggctcgg gtaccgcatg ccgggagcca gtgacttctt tctggccctc
     9541 gccgggatgg gactgctgga cgcctcggag gccggagagt tccgtaactc ccctgccgcc
     9601 gaccggtatc tggtgcgcac ccgcccggaa ttcatcggcg gctacctcca gttctgtgag
     9661 cgcgagctga acccggcctg ggaaggtctc gggacggcgc tacgcacggg cgccccacag
     9721 aatcccgccg cgctggaggg caacccgtac gaaactctct accaggaccg ggaatcgacg
     9781 gaatcgttcc tggagagcat ggacacactc aacacgcccc tcctgcggcg cctgggcgag
     9841 atcgactgga gcggctacga ctcgttcgtg gacgtcggcg gcgcgcgcgg caacgtcgcc
     9901 caccatctgg cgctgaacaa cccgcatctg aagggcgcgg tgttcgatct gccgcagttg
     9961 gagggggcct tcaccaccca catggccgcc ctcggcgacg acggggcggt ctcgttccac
    10021 ggcggcgact tcttcgccgg cccgctgccc gagtccgatg tgctcatctt cggtcatgtg
    10081 ctccacaact ggggtgtgga cgagcgccgc acgctgctgc gcaaggcgca cgacgcgatc
    10141 cggccggggg gagcggtcat catctacgac cccatggtca gcaacagcgc gccaccgctc
    10201 tacgcgacgc tcgccgcgct gagcatgctg gtgtggtccg cgggcggcgg cgagtacccg
    10261 gtcagtgact gccacgcgtg gctcgaagag gccggattcc gccctgagac ggtcggtccc
    10321 gaggacacac cggacgacgt tctggtcatc gggcgaaaga gctgagcacg gcccgcggga
    10381 ctactcggtg accggcaggc gcgaagcaca cgacggcgct gtcagcaagg acgtgaggag
    10441 agacaatgga tgcttccgtc atggtcgtgg gagcggggcc ggcgggtctg atgctcgccg
    10501 gagagctgcg tctggccggg atcgatgtgg tggtcctgga ccgtctcccg cagcgcaccg
    10561 gagagtcccg gggcatcggg ctcacccccc gcaccgtgga agtcctggac cagcgtggcc
    10621 tgttgccgcg cttcggcgac atcgagatga gcagcctcgg gcacttcggc ggaatacccc
    10681 tggatttcgg tgtcctgggc ggtggcgacc gggccgccag gaccgtgccg cagtccgcca
    10741 ccgaatccgt actggagagc tgggcccgcg aactcggcgc ggacatccgc cgcgaccacg
    10801 agttcaccgg cctgacggac cacggcggcc atgtcgaggc gcaggtacgc ggcccggcgg
    10861 gccaacaggt cctgagctgc cgctttctgg tcggatgcga cgggggccgc agcgccgtgc
    10921 gcaaggccgc cggcttcgac ttccccggca ccccggccac caccgagctc ctcctcgcgg
    10981 atatccgggg tgtcgatctg gagccgcgca tggtcgccga ccgggtcacc gacggcatgg
    11041 tcatgaccgc ccggctcggg gacggcgtcc accgcgtcat cgtcgccgaa cgcggtgcgc
    11101 cgccgcagcg gaggacgggc ccgcccgcct tcgccgaggt cgccgacgcc tggaagcggc
    11161 tcaccggcat cgacatctcg cacgccgaac ccgtgtggct cagcgccttc ggcgacgcca
    11221 cgcgtcaggt caccgagtac cgccgcggca gggtgctgct ggccggggac tccgcccaca
    11281 tccacctccc ggccggcgga cagggcatga acaccagcgt tcaggactcg gtgaacctgg
    11341 gctggaaact cgctgccgta ctgcacggcg ccgccggccc cgcgctgctc gacacgtatc
    11401 acaccgaacg ccacgaggtc ggccgtcggc tcctcgccaa cacccgcgcc cagagcctgc
    11461 tgatcctcgg cagcgaggag gtgcagccgc tgcgcgacat cctgaccgag ctggcgcggt
    11521 acgaggaggt cgcccgccac ttcgcggcca aggcgggggg actggacatc cgctacgacg
    11581 tcgggagcgg ccccaacccc ctgctgggga tgcggatgcc gcggttggag ctgttgcggg
    11641 gcaccaccgt cacctccagc accgagctgc tccgggccgg ccggggcgtg ctgctcgacc
    11701 tggccgatac gccgcggctg cggcggcgcg cggccccctg ggcggaccgt gtcgacctgg
    11761 tcaccgccgc tccccggggc actgccgccc tcggcggcgg gctcgacggg acgagcgccg
    11821 tactgctgcg ccccgacggc cacgtcgcct ggatcgcacc cggcagccac cacgacctgc
    11881 cgatggccct ggagcgctgg ttcggccccg cccggcagca cggtacggcg cacacacgcg
    11941 ccgtatgacg caacgccctt cgttcccacg cgcagagaga ggtcgaggat gtacagcaca
    12001 ttgattgtcg cccggatgga acccggttcc gccggtgagg tggcccggca cttctccgcc
    12061 ttcgacgcta cggagatgcc ggaactgatg ggaacgcgcc ggcgcgagct cttctcgttc
    12121 cgggggctct acttccacct tcaggatttc gacggtgaga acggcggcga gcggatcgaa
    12181 cagacgaagg gggacccgcg gttcgtcggg atcagccagg atctgaagcc gttcatcgac
    12241 gcgtacgacc cggcgacctg gcgctccccc gccgacgcga tggcgcggcg cttctaccac
    12301 tggagcgccg agtgagtgcc gtatacgggc gccaggtcgt catcaccggg atcggagtca
    12361 cggcaccggg cggaccgggg acgaaggggt tctggcagct cctcaccgac ggccgtacgg
    12421 ccacccggcg gatctcgttc ttcgacccct cgccctttcg ctcccaggtc gccgcggaag
    12481 tggacttcga cgccgaggcg tgcggtctcg gcccgcagga gatccggcgc atggaccgcg
    12541 ccgcgcagct cgcggtggtc acggcgcgcg aggcggcggc cgacagcggg cttgccttcc
    12601 acacgctgga tccgggccgc atgggggtga ccatcggcag cgccgtgggc gccaccatgg
    12661 gtctcgacga ggagtaccgg acggtcagcg acggcggccg ccgggagctg gtcgaccacg
    12721 agtacgccgt tccgcacctc tacaactaca tggtccccag ctccttcgcc gccgaggtgg
    12781 cccacgcgat gggtgccgag gggcccgcct cggtcgtctc cacgggatgc acatccggcc
    12841 tggacgcggt cggctacgcc accgaggtga tcagggaggg cacggcggac gtcatgatcg
    12901 ccggtgcgac ggaggcgccg atctcaccga tcaccgtggc ctgcttcgac gccatcaagg
    12961 cgaccacgcc gcgcaatgac gatcccgcgc acgcctcgcg gcccttcgac gcgagccgca
    13021 acggcttcgt cctgggcgag ggcgccgccg tcttcgtcct ggaggacggg gagagcgccc
    13081 ggcggcgcgg cgcccatgtc tacgcggagg tggcaggcta cgcgacgcgc tccaacgcct
    13141 tccacatgac cggactgcgc cccgacggca aggagatggc ggaggcgatc cgcatcgcca
    13201 tagcggaggc ccgcgtcaac ccggaggaca tcgactacat caacgcccac ggctcgggca
    13261 ccaagcagaa cgaccgccat gagaccgcgg ccttcaagct gagcctgggc gaggcggcgt
    13321 accgcacacc ggtcagctcc atcaagtcca tggtcggcca ctcgctcggc gcggtcggct
    13381 ccatcgagct cgccgcctcc gcgctggcga tggagcacca cgtcattccg cccacggcca
    13441 atctccacac cccggacccg gagtgcgacc tggactacac gcccctcacc gccagggagc
    13501 ggcgcacgga caccgtgctg tcggtgggca gtggcttcgg cggcttccag agcgcggtgg
    13561 tgctggcccg gcccgacagg aggaggcgat gaacgccacc accgtggtga cgggactcgg
    13621 cgtggcggcg cccaacggtc tgggtctgga gtcctactgg tcggccgtgc tggcgggccg
    13681 gggcgccatc ggccgggtcg gccggttcga ccccacgtcc tatcccgctc aactggctgg
    13741 ggagatcgcc gggttcaccg ccgaggacca cctgcccagc cggctgctgc cccagaccga
    13801 tcggatgacc cggctggcgc tggtcagcgc cgactgggcg ctggaggacg cgggggtcgt
    13861 accggacacc ctgcccgcgt acgacatggg tgtcatcacg gccagtcatt ccggcgggtt
    13921 cgagttcggc cagaaggaac tccgggcact gtggagcaag ggcggccggt atgtgagcgc
    13981 gtaccagtcc ttcgcgtggt tctacgcggt caacagcggc cagatctcga tccgcaacgg
    14041 tatgcgcggc cccagcgggg tcgtcgtcag cgaccaggcc ggcggtctgg acgcgctggc
    14101 ccaggcccgc cggcagatcc gcaagggcac accgctgatc gtctccgggg ccatcgacgc
    14161 ctcgatctgc ccctggggct gggtggccca gctcgcgagc ggccggctca gccgcgccac
    14221 cgatcccggg cgggcctatg tgcccttcga cgacggcgcc gcggggcacg taccgggaga
    14281 gggcggagcg ctgctcatcc tggaggacgc cgaccacgcc cgcgcccgcg gggcacggca
    14341 ggtgtacgcc gagatcgccg gccatgcctc caccttcgac cccgcgccgg gcggcgaccg
    14401 cggcccgggg ctgcgacggg cggtcgaaca ggcgctgtgc gacggggaaa cggcgcccgg
    14461 cgacgtggac gtggtgttcg cggacgcggc cgcggtgccg gaactcgacc gggtcgaagc
    14521 cgaggcgatc agcaaggtct tcggcccccg ggcggtaccc gtgaccgcac ccaagaccat
    14581 gaccgggcga ctgtactcgg gcgccgcccc gctggacgtg gccaccgcct gtctcagcat
    14641 cagggacggc gtcatcccgc cgaccaccaa cacctcgctc tcccctcact acgacatcga
    14701 tctggtgacc ggcccgccgc gcgagacacc cgtgcgcacc gcgctcgtac tcgcccgcgg
    14761 ctacggcgga ttcaactccg cggtcgtggt gcgcgcacca cgcgactgat ccaccggccc
    14821 ggaaatgcgc aagccctcca cccatgcgtt tcgaggaagg accctcatgc ccgcgacccc
    14881 cttcaccatc gacgacctca agtccatcct gcgcgagggc gccggcgccg acgagggcgt
    14941 cgacctcgac ggagacattc tcgacgcgga gttcgacgcg ctgggttacg agtccctggc
    15001 gatgctggag accgccggcc gtatcgagcg ggagtacggg atcagcctcg acgaggagat
    15061 cttcgccgac gcccgcacac cgcgtgcgct gatcgctctc gtcaacgggc aacttccctc
    15121 cgctcaggcc gtctgagccg ctcccctccc cccccggaac caggagatac agaatgacgc
    15181 aggacatagt gaaggtcgcg cttgtgaccg gtgccaccag cggtatcggc ctggccacca
    15241 cccggctgct ggccggacag ggccacaagg tcttcctgtg cgcgcgcacc gaggacgacg
    15301 tgtcgcgaac ggtcaaggaa cttcggggcg agggactgga ggtggacggc agggcagcgg
    15361 acgtgtgctc gaaggacgac atccgggacc tggtccgggc agccgtcggc cgcttcggtc
    15421 ccatcgacat cctggtgaac aacgcgggcc gcagcggcgg cggggtcacc gccgacatcg
    15481 ccgacgagct gtggttcgac gtcatcaaca ccaacctcaa cagcgtcttc ctcgtgacgc
    15541 gcgaggtgct gaccaccggc ggaatgcgcg acaggcccgg gggacgcgtc atcaacatcg
    15601 cgtccacggc cggtaaacag ggcgtcgtcc tgggtgcgcc ctactccgcc tccaagcatg
    15661 gtgtcgtcgg cttcaccaag gcgctgggca acgaactggc cccgaccggc atcaccgtca
    15721 acgccgtgtg ccccggctat gtggagaccc cgatggcgca gcgggtgcgc cagggctacg
    15781 ccgccgcgta cgaggtcgac gaagagcaga tcctggagaa gttcaccgcc aagatcccgc
    15841 tcggccgcta ctccaccgcg gaggaggtcg ccggtctggt cggctacctc acctccgaca
    15901 ccgcggcgtc catcaccgcg caggcgctca acgtctgtgg cggcctcggc aacttctgac
    15961 ccggccggcc cccggctccc cggccggacc cgatgtgccc accactgcca aggagatgaa
    16021 catgaccgag caggcgcccc gcgaagtcga gcacgagatc accgtgtccg cccctgcccc
    16081 ggaggtctac cgcctcctcg cggaggtgga gaactggcca aggatcttcc cgccgtcggt
    16141 gtacgtcgac tacgtggaga agaacggtga cgaggagcgc atccggatct gggccacggc
    16201 caacggcgag gccaagaact ggacatcacg ccgccggctc gacccggcgg gcctgcgtat
    16261 caccttcggt caggaggttt ccgcgccgcc ggtcgccgag atgagcggta cgtggatcat
    16321 cgagccacag ggggcggggt gccggctgcg gctgctgcac tcctaccgtg ccatcgacga
    16381 cgatccggcg ggcctggcgt ggatcgaccg ggccgtggac cgcaacagcc gctccgaact
    16441 cgccgcgctc aagacgaatg tggagctggc cgcgcactcc gccgagctga cgctgacctt
    16501 cgaggacagc gtacggatca acggctcggc caaggacgcg tacgacttcg tcaacgaggc
    16561 ccagctgtgg accgatcggc tgccgcatgt ctcccgggtc tcgctgaccg aggacgaacc
    16621 gggagtccag accctgcgca tggacacggt cgcgaaggac ggctccacgc acaccacgga
    16681 gtcggtcaga gtgtgcttcc cgcaccacgg gatcgtgtac aagcagacca cgctgcccgc
    16741 cctgatgacc ctgcacaccg gcagctggcg gttcgacgag ggaagtgacg gcgtcaccac
    16801 cgcgacgtcc cggcacaccg tggtcatcaa caccgagaac atcatgcgga tcctcggacc
    16861 ggacgccgga atcccgcagg cccgcacctt cctgcgtgag gcgctgggag ccaacagccg
    16921 ggcgacgctg gggcatgcca agtcctacgc ggaagcgcgg cgctgaagga tgggcggctc
    16981 agcggacgcc gacgtcctcg tcgtcggtgc cgggcccgtc gggctgctgc tcgcgggtga
    17041 ggtgagcgcc ggcggcgcca ggaccgtcgt actggagcag ttggccgggc cgaccgccga
    17101 gtcccgcgcc tcgatcctcc acacgcggac catggagatc ctcgccgaaa ggggcatcct
    17161 cgaccgtttg ggtgatctcc cggccggtgg gcgcggccat ttcggcggga tcccgttcga
    17221 tctggccgag gcggacccgg ggcaccccta cgccggccag tgggagtgcc tccagagccg
    17281 cctcgaaccc gtcctggagg catgggccgt ggagcggggc gccgaggtac gccgggggca
    17341 cgtggtcacc ggactgacac agcacgacga ccgggtggag gtggtggcgt tcggccccgg
    17401 cggaaggagc caccgcctca cggccgccta tgtggtggga tgcgacgggg agcagagcac
    17461 cgtacgccga ctcgcgggct tcgcgatgac gggcgacgac gccaccaggg agatgctccg
    17521 ggccgacgta ctgggcatcg acatcccggg ccggcgcctc agacggtacg cggacggcac
    17581 cgccaccgcc caccggcgcg gcgacgggac cacccgtctc atggtgcacg accgcacccg
    17641 tgcacccggg cctcgtaccc gcgagcccga gttcgccgag gtcgccgcgg cgtgggcccg
    17701 ggtgacgggc gaggacatca gcggcggcac ggcggtgtgg ctcaacagct tcgacgacac
    17761 ccggcgccag gcgcgggact accgccgagg ccgggtcctt ctggcggggg acgccgccca
    17821 tgtccagatg cccgtcggcg gacaggcact caacctcggg ctccaggacg cggccggact
    17881 cggccggagg ctggcggccc gcatcaccgg cgggacgggc gacggcggtc tggacgaata
    17941 ccacacggag cgccatgccg cgggcacccg caccctgacc aacatccagg cccaggcgct
    18001 gctgctgttc ggcgggcccg aggtggacgg catccgcgag gtgtgcggcg agctcctcgg
    18061 catggacgtc gtccgccgcc acctcgcccg gacgatcagc ggcctggacc ggccggcccc
    18121 accgcccgcg gcggacacca ctccacccct ctcagcacac gggagtccca ccatggacag
    18181 gctcactgga aagacggcgc tggtcaccgg ctccagccgg ggcatcggcc gcgccacggc
    18241 cgtacggctg gcccgcgaag gcgccctggt cgccgtgcac tacgccacca acgacgaagc
    18301 ggcgctggag accgtcgccc tgatcgagaa ggagggcggc cgggcctttc cggtccgcgc
    18361 cgaactcggc gtccccgggg atgtgcacga gctcttcttc ggcctggagc aggggctgaa
    18421 ggagcggacc ggggaaaccg cactcgacat cgtggtgaac aacgccgcgg tgacgggctc
    18481 ggacggcatc agccccgagg acgtcacccc ggagcagctc gaccgctact tcgcggtgaa
    18541 cgcacgggcg ccgtacctcg tcatccagcg ggcactgcgg aacatgcccg acggggggcg
    18601 cgtcatcaac atctccaccg cgctcacccg caccgcggtg cccgagcagg tcgcctatgc
    18661 gatgaccaag ggggccatcg agcagatctc gctgcacctg gcgaagcatc tggcgccgcg
    18721 cgggatcacc gtcaacagtg tggcgccggg gatcacggac aacggcgggc cggtcttcga
    18781 catccccgag gccgtcgagc agatggcgca ggtctccgcg ttcaagcggg tgggtgacgc
    18841 cggggatgtc gccgacgtgg tgaccttcct ggccaccgac gaggcgcgct ggatcacggg
    18901 ttcgttcatc gacgccagcg gcgggacgct cctcggatga ccggccctta cgcacaccgc
    18961 gagagaggaa gcgaagcatg acctccgaca gtccccgtat cacgctcgtc accggcgcca
    19021 acaagggaat cggacgcgcc gtcgtccggc gcctcggcga gctgggccag cgtgtctatc
    19081 tgggcgcccg ggacgtggag cggggcagga acgccgagcg tgagctgcgt gccgagggac
    19141 tcgatgtccg cttcgtacag ctcgatgtca cggacgagtc ctcggtggcc ctcgccgcca
    19201 agcgcatcga ggaggagacg ggccacctgg acgccctggt caacaacgcg gggacgggcg
    19261 cgccggtacg cgcgcccagc cggacgccgg ccagtgtggt gcgccgcacc tatgagacca
    19321 atgtgttcgg tgtcatcacc gtcatcaaca cgatgctgcc gctgctgcgc cgctcgcggg
    19381 ccgcccgcat cgtcaacgtc agcagtgtgg tcggatccct gacccatgcc gcggccctgg
    19441 acgatcccac cggggagttc cccaagggga cgtacccggc ggtgctggac tacggcacgt
    19501 cgaaggcggc gctgaacgcc gtcaccatca cctacgccaa cgagctgcgc ccggagcgga
    19561 ttctggtcaa cgccgtctca cccgggttct gttcgaccga tatcaacggc caccagggtc
    19621 atctgacgcc ggagcagggg gcgcgtatcc ccgtactcct ggcgactctg ggcgacgacg
    19681 gcccgacggc cgtcttcctg ggcgaggacg gctccccgac cggtcagcgg ctggcatggt
    19741 gacgaccgtg gtccgagtgg acggaccgag cgaaccgacc gacctggacg acctgggcga
    19801 gctgggcgag cggaagaggc tcgccgagca ggggccggac ccccgggcca ccgagcggca
    19861 gcatgccaag ggcaaactga ccgcccggga acggatcgcc ctcctcctcg acaagggcag
    19921 cttcaccgag gtcgaggcgc tgcgccggca ccgggcgagc ggcttcgggc tggaggcgaa
    19981 gcgcccctac accgacggcg tggtgacggg ctggggaacg gtcgagggcc ggacggtctt
    20041 cgtctacgcc cacgacttcc ggatcttcgg cggggcgctg ggcgaagccc atgcccagaa
    20101 gatccacaag atcatggacc tggccgtcgc ggcgggcgcc ccgctcgtgt cgctcaacga
    20161 cggtgccggg gcccgtatcc aggaaggagt ctccgccctc gcgggctacg ggggcatctt
    20221 cagccgcaac acccgggcat ccggggtcat cccgcagatc agtgtgatgc tgggaccgtg
    20281 tgcgggcggc gccgcctact ccccggcgct caccgacttc gtcttcgcgg tccgcgggat
    20341 ctcgcagatg ttcatcaccg gccccgatgt cgtgcaggcc gtgacgggcg aggagatatc
    20401 gcaggacggc ctgggcggcg cggatgtcca cgccggtgtc tcgggcgtgg cccacttcgt
    20461 gtacgacgac gaggagacct gcctggcgga ggtgcgcttt ctgctctgcc tgctgcccgc
    20521 caacaaccgc gaactgccac ccgtcgcacc cggcgtggac cgggcggacc ggctgtgcga
    20581 tgcgttgccc ggactcgttc ccgacgaggc cggccactcc tacgacatac gcgcggtgat
    20641 cgaggaactc gtcgacgagg gcgagcacat ggaggtccac gccgtgtggg cgcccaatct
    20701 cgtgtgctcg ctggcccggc tggacggcca ggtggtgggc atcgtcgcca atcagcccgc
    20761 cgcgatggcc ggcgtactgg acatcacggc gtccgagaag ggcgcgcgct tcgtccagtt
    20821 ctgcgacgcc ttcaacattc ccctcgtcac cctcgtcgat gtgcccgggt tcctcccggg
    20881 cgtgcggcag gagcacgagg ggatcatccg gcgcggtgcg aagctgctgt acgcgtactg
    20941 caacgcgacg gtgccccgga tctcggtggt cctgcgcaag gcctacggcg gcgcctacat
    21001 cgtgatggac tcccgctcga tcggtgcgga catcgcgctg gcctggccgg ggaacgagat
    21061 cgccgtgatg ggcgcggagg gcgccgccaa tgtggtcttc cggcgggaga tcgccgccgc
    21121 cgaggacccg gaggagacgc gccgccaaaa gatcgaggat tacaagcggg agctggtgca
    21181 cccgttctac gcggccgaac gcggcctggt cgacgatgtc atcgatccgc gggagacccg
    21241 ctcggtgctg atccgctcgc tctccatgct gcggacgaag gactccggtc tgccgcgccg
    21301 caagcacgga aacccgccgc agtga
//
