LOCUS       BGC0000244             10029 bp    DNA     linear   BCT 07-JUL-2000
DEFINITION  Streptomyces griseus subsp. griseus macrotetrolide biosynthesis gene
            cluster, downstream region.
ACCESSION   BGC0000244
VERSION     BGC0000244
KEYWORDS    .
SOURCE      Streptomyces griseus subsp. griseus
  ORGANISM  Streptomyces griseus subsp. griseus
            Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
            Streptomyces.
COMMENT     [WARNING] On Jun 10, 2016 this sequence was replaced by AH009582.2.
            ##antiSMASH-Data-START##
            Version      :: 6.2.0-924c3663(changed)
            Run date     :: 2022-11-07 17:54:36
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..10029
                     /db_xref="taxon:67263"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces griseus subsp. griseus"
                     /strain="DSM 40695"
                     /sub_species="griseus"
     subregion       1..10029
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0000244"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..10029
                     /contig_edge="True"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            205..990
                     /gene="nonH"
     CDS             205..990
                     /codon_start=1
                     /gene="nonH"
                     /note="similar to FixA"
                     /product="flavoprotein reductase nonH"
                     /protein_id="AAF81240.1"
                     /transl_table=11
                     /translation="MSLRIVVCVKYVPDATGDRRFADDLTLDREDVDGLLSELDEYAVE
                     QALQIADGADDAEITVVTVGPEDAKDALRKALSMGADKAVHVEDDDLHGSDVMGTSLVL
                     AKAVEKAGYDLVICGMASTDGVMGVLPALLAERLGVPQVTLLSEVAVDGGVVTGRRDGD
                     TASEQLEASLPAVVSVTDQSGEARYPSFKGIMAAKKKPVESLDLDDLGLDADEVGLAGA
                     WTVVDSATERPARTAGTIVKDEGEGGRQLAGFLAGQKFI"
     CDS             1051..2013
                     /codon_start=1
                     /note="orf26; similar to FixB"
                     /product="flavoprotein reductase"
                     /protein_id="AAF81241.1"
                     /transl_table=11
                     /translation="MAEVLVLVDHVDGAVRKPTLELLTLARRVGDPVAVVLGAGAGDAA
                     PVLGEHGAVKVLTSDAPEFADYLVVPKVDALQAAFEAVSPVAVLVVSSAEGKEIAARLA
                     LRVGSGIITDATDLEAGDQGVVATQAAFAASFTTKSRVSRGVPVITVKPNSAPVEPAPA
                     AGAVEALPVSFGEAATGTKVTSRTPRESTGRPELTEAAIVVSGGRGVNGAENFPLIEAL
                     ADSLGAAVGASRAAVDAGWYPHTSQVGQTGKSVSPQLYIASGISGAIQHRAGMQTSKTI
                     VAINKDAEAPIFELVDYGVVGDLFAVVPQLTEEINTRKG"
     CDS             complement(2090..3481)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1080:lysine/ornithine N-monooxygenase (Score: 381.3;
                     E-value: 8.3e-116)"
                     /gene_kind="biosynthetic-additional"
                     /note="orf27"
                     /product="amino acid monooxygenase-like protein"
                     /protein_id="AAF81242.1"
                     /transl_table=11
                     /translation="MTPGPRTPPLDLLGVGAGPFNLSLAALADGVPGLRTAFHEQRAAF
                     HWHPGLLIEGATLQVPFLADLVSLVEPTSPWSYLNYLKIRRRLFPFYFAEHFHIHRTEF
                     DNYLRWVSTELPATRFGHRVDTVAWDPGQDAFAVEFTRLGPDGETLTTGLTHARNLALG
                     VGTAPHVPEPLRELVQDPAAAVLHSADYLSQRNRLLAARHITVVGSGQSGAEVLLDLLR
                     SRPEGAEGLTWLARTPAFAPMEYSKIGLEQFTPDYTRYFHGLPQATRDRLLPRQWQLYK
                     GVSGDTLGDIHDELYRRSLGGGWPDVTLTPGIEVTGAAVTEAGRIELGVEHGQQEARGR
                     LVTDAVVLATGYRERPVDLLLAALDPYIVRDETGRPQVDAAQRLVLAPEIAGSVFVQNA
                     ERHTHGVGTPDLGLAAWRSAVIVNTLTGKEFYPLPERTAFTTFGLGARDRDDRDTASRP
                     AEERR"
     CDS             complement(3552..5129)
                     /NRPS_PKS="Domain: Aminotran_5 (143-273). E-value: 9.1e-11.
                     Score: 33.1. Matches aSDomain:
                     nrpspksdomains_AAF81243.1_Aminotran_5.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1180:Decarboxylase, pyridoxal-dependent (Score: 278.2;
                     E-value: 1.8e-84)"
                     /gene_kind="biosynthetic-additional"
                     /note="orf28"
                     /product="amino acid decarboxylase-like protein"
                     /protein_id="AAF81243.1"
                     /transl_table=11
                     /translation="MSDGTPPIPGPAGPREGLVAGGAHGPGRLRALTAIVLDALEDAAP
                     ARGGPLPAGGPEVVALSTLARCAPVLPEEGVGPEAALGDVVRAVAEGAADPADPACVAH
                     LHCPPLAVAVAADLAGAALNPSMDSWDQAPAAGVIEELTTAALARLIHPTAPAPDALIT
                     SGGTESNLVALLLARERAVPGTLRVVTGANAHHSVHRAAWMLGLPAPVVVACRDGRIDP
                     AALDDALASLAGAPLLVVATAGTTDEGRIDPLPEIARVAERHAARLHVDAAYGGPLLFS
                     ERLAPLLAGLEHAASVTFDLHKLGWQPVAAGVLAVADAGMLAPLSLRADYLNADDDTEA
                     GLPDLLGRSIRTTRRPDALKMAVTFRALGRRGLGELVEHCVRTAHEFGRAVDTRPGLRR
                     RPGDIGISTVLFRPTVADALPDEAGDAVVAAVRRTLLAEGRAVLGRAQAEDGDGRRRLW
                     LKATLLHPDAAAAELLPLLDLVTAAADRAATEAEADGVVTGADADRAATEAPGAEDTDA
                     PAAERLSP"
     aSDomain        complement(4311..4700)
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AAF81243.1_Aminotran_5.1"
                     /evalue="9.10E-11"
                     /label="AAF81243.1_Aminotran_5.1"
                     /locus_tag="AAF81243.1"
                     /protein_end="273"
                     /protein_start="143"
                     /score="33.1"
                     /tool="antismash"
                     /translation="TAALARLIHPTAPAPDALITSGGTESNLVALLLARERAVPGTLRV
                     VTGANAHHSVHRAAWMLGLPAPVVVACRDGRIDPAALDDALASLAGAPLLVVATAGTTD
                     EGRIDPLPEIARVAERHAARLHVDAA"
     CDS             complement(5438..6403)
                     /codon_start=1
                     /note="orf29"
                     /product="unknown"
                     /protein_id="AAF81244.1"
                     /transl_table=11
                     /translation="MREVTCHEVGAQRLDEALSGIGGRTMGRWHGMRYDDASPERLRET
                     ADELLDHVAARVAADALLDDVARSALRTAAECHLGEMSVGCFPDGDQELHFPLIGETLT
                     SEDIAFGDVVRFGGGQAPSAGTWLDAFAVSLVSGLVWDWQRVIGLLLRNDYAPAIHDGV
                     PYSKLDSASDPTDLAAMDALCPYLAEAEGHQPRHWPTVPLRRPDADELALAAAKLDASG
                     ALTPDQRLLRVLLDDDQAAFEEALASRLVGHRASVGPDPAPRTLLPLHALALAALAVQA
                     HGWELGLRSGYLPPELLGTPDALRRAGESRTNNLGGWYAK"
     CDS             complement(6526..8850)
                     /codon_start=1
                     /note="orf30"
                     /product="5-methyltetrahydropteroyltriglutamate-
                     homocysteine methyltransferase-like protein"
                     /protein_id="AAF81245.1"
                     /transl_table=11
                     /translation="MTAKPAAAAARATVYGYPRQGPNRELKKAIEGYWKGRVDAAALRE
                     TAAELRRGTWQQLAEAGVHDVPTGDFSYYDHVLDTSVMVGAVPGRHRAAVDADALDGYF
                     AMARGTQDVAPLEMTKWFDTNYHYLVPELGPDTVFTADSAKQVAECAEALALGHTPRPV
                     LVGPVTYLLLAKPAPGVAADFEPLTLLDRLLPVYAEVLADLRAAGAAWVQLDEPALVQD
                     RTPAELNAAARAYRELGGLADRPQLLVASYFGRLGEALTVLAKAPVDGLALDFTESGAG
                     NLDDLAAAGGLPGKRLVAGVVNGRNIWINDYEKSLATLGTLLGLADRVDVSASCSLLHV
                     PLDADAERDIDPQIARWLAFARQKTEEIVVLARGLTGGTDTIAAELAANRADLASRAGA
                     ALTRDPAVRARTAAVTDADGRRSQPYTERSAAQRAHLGLPLLPTTTIGSFPQTTELRTA
                     RADLRAGRIDEAGYEERIKDEIREVLSFQEKAGLDVLVHGEPERNDMVQYFAEQLTGYL
                     ATQHGWVQSYGTRYVRPPVLAGDISRPEPMTVRWTTYAQSLTARPVKGMLTGPVTMLAW
                     SFVRDDQPLGDTARQVALALRDEVNDLEASGTSVIQVDEPALRETLPLRAAEHAAYLEW
                     ATESFRLATGGVRPDTQIHTHMCYAEFGDIVQAIDDLDADVISLEAARSHMQVARELAA
                     HGYPREAGPGVYDIHSPRIPSTEEAAALLRKGLEAIPASRLWVNPDCGLKTRGWPETRA
                     SLENLVAAAREIRAELPTEAA"
ORIGIN
        1 agccggaagg ccgcctgtgc gagcacctcc cgcatgggtg ccttcttctc ggatcctcgc
       61 gcctcgctca tgcggcgaaa cgtagcaccg cgaggaggat tttggcactg cgtaccttta
      121 cagagggtac tgagtgccat aatctctcca tcagtacgaa tgacacccag gtgggaccac
      181 acccaggtag gcaggagagc cggcgtgagc ttgaggatcg ttgtctgtgt gaagtacgtg
      241 cccgacgcga ccggtgaccg gcgtttcgcc gatgacctga cgctggaccg tgaggatgtc
      301 gacggtctgt tgtcggagct ggacgagtac gcggtcgagc aggcgttgca gatcgctgac
      361 ggggcggacg atgcggagat caccgtggtg acggtgggtc cggaggatgc caaggacgcg
      421 ttgcgcaagg cgttgtcgat gggtgcggac aaggcggttc acgtcgagga cgacgatctg
      481 cacggcagtg atgtgatggg gacgtcgctg gtgctggcga aggctgtgga gaaggccggg
      541 tatgacctgg tgatctgtgg gatggcgtcg acggacggtg tgatgggtgt gctgccggcg
      601 ttgctggcgg agcgtctggg tgtgccgcag gtgacgttgc tgtccgaggt cgcggtggac
      661 ggtggtgtgg tgacggggcg gcgtgacggt gacacggcgt ccgagcagct tgaggcgtcg
      721 cttcccgcgg tggtgtcggt gaccgaccag tcgggtgagg cccgttaccc gtcgttcaag
      781 gggatcatgg cggcgaagaa gaagccggtg gagtcgctgg acctggacga tctgggtctg
      841 gacgcggacg aggtcggtct ggcgggtgcg tggacggtgg tggattccgc caccgagcgt
      901 ccggcgcgga cggcgggcac gatcgtgaag gacgagggtg agggcggcag gcagctcgcc
      961 gggttcctcg cgggccagaa gttcatctag tccgcatgtc tttccccgct gttcctctct
     1021 ctcgtccttt cttgtctgga gtgcgttgtc atggctgaag ttcttgttct ggtcgatcac
     1081 gtggacggtg cggtccgcaa gcccaccctg gagctgctga cgctggcgcg tcgtgtcggt
     1141 gacccggtcg ccgtggtgct gggtgccggt gccggggacg ctgccccggt gctgggtgag
     1201 cacggtgcgg tgaaggtcct gacctcggac gccccggagt tcgcggatta tctggtggtg
     1261 ccgaaggtcg acgcgctgca ggcggcgttc gaggcggtgt ccccggtcgc ggtgctggtg
     1321 gtgtcgtccg ccgagggcaa ggagatcgcc gcccgtctcg cgctgcgggt gggttccggc
     1381 atcatcaccg acgccaccga tctggaggcc ggtgaccagg gtgtggtcgc gacgcaggcc
     1441 gcgttcgccg cgtcgttcac cacgaagtcc cgggtctccc ggggggttcc ggtcatcacg
     1501 gtcaagccga actccgcccc cgtcgagccg gccccggcgg cgggtgcggt ggaggctctg
     1561 ccggtgtcgt tcggtgaggc ggcgacgggg acgaaggtga cgtcgcggac gccgcgtgag
     1621 tcgaccgggc gcccggagct gaccgaggcc gcgatcgtgg tctccggtgg ccgtggggtc
     1681 aacggtgcgg agaacttccc gctgatcgag gcgctggccg acagtctggg tgcggcggtg
     1741 ggcgcgtcgc gtgccgcggt cgacgcgggc tggtacccgc acaccagcca ggtcgggcag
     1801 accggcaagt ccgtctcgcc gcagctgtac atcgcttcgg gtatctccgg ggcgatccag
     1861 caccgggcgg gtatgcagac ctcgaagacg atcgtcgcga tcaacaagga cgccgaggcc
     1921 ccgatcttcg aactcgtcga ctacggcgtc gtcggcgacc tcttcgccgt cgtgccccag
     1981 ctcaccgagg agatcaacac ccgcaagggc tgaccccctg gcgaacaccc ccgccccggg
     2041 ccgcacggtg aaccccaccg cgcggcccgc ggccgttccg ggaccgtcgt caccgtcgtt
     2101 cttcggccgg acgtgacgcg gtgtcccggt cgtcacggtc ccgcgcgccg agaccgaacg
     2161 tggtgaaagc cgtccgttcg ggcagcgggt agaactcctt gcccgtcagc gtgttgacga
     2221 tgacggcgga acgccaggcg gccaggccca ggtccggtgt cccgacgccg tgtgtgtgcc
     2281 gctcggcgtt ctgcacgaag acggaaccgg ctatctccgg tgcgaggacg agccgttggg
     2341 ccgcgtcgac ctgcggacgc ccggtctcgt cgcggacgat gtacgggtcg agagcggcga
     2401 gtagcaggtc gacggggcgc tcccggtatc cggtggcgag gacgacggcg tccgtgacga
     2461 gccggccccg cgcctcctgc tggccgtgct cgacgcccag ctcgatgcgg cccgcctcgg
     2521 tgacggctgc gccggtgacc tcgatgccgg gggtgagggt gacatcgggc cagcccccgc
     2581 cgaggctgcg ccggtacagc tcgtcgtgga tgtcccccag cgtgtccccg ctgacgccct
     2641 tgtacagctg ccactggcgg ggcaggagcc ggtcccgggt ggcctgcgga agtccgtgga
     2701 agtagcgggt gtagtcgggg gtgaactgct ccaggccgat cttgctgtac tccatgggcg
     2761 cgaacgcggg cgtacgggcc agccaggtca gcccctccgc cccctcgggc cgggaccgca
     2821 gcaggtccag caggacttcg gcgcccgact ggcccgagcc gacgacggtg atgtggcggg
     2881 cggccagcag ccggttccgc tgggagagat agtccgcgga gtgcaggacc gcggcggccg
     2941 ggtcctggac cagctcccgc agcggttcgg ggacgtgcgg ggccgtgccg acgccgaggg
     3001 cgaggttacg ggcgtgggtg agcccggtcg tgagcgtctc cccgtcgggc cccagccggg
     3061 tgaactccac ggcgaacgcg tcctgtccgg ggtcccaggc caccgtgtcg acccggtggc
     3121 cgaagcgggt ggcggggagt tcggtgctca cccagcgcag atagttgtcg aactcggtgc
     3181 ggtggatgtg gaagtgctcg gcgaagtaga acgggaagag cctgcggcgg atcttgaggt
     3241 agttgaggta ggaccagggg ctggtgggct cgacaaggct caccaggtcg gccaggaacg
     3301 gaacttggag cgtcgcgccc tcgatgagca gcccggggtg ccagtggaag gcggcgcgct
     3361 gctcgtggaa ggcggtgcgc agcccgggga cgccgtcggc gagcgcggcg agcgagaggt
     3421 tgaagggccc tgcccccacc cccagcagat cgaggggcgg cgtgcgcggt ccgggtgtca
     3481 tcgggttcct ccggcggggg tcgctggggt ggcggggggt cgtcccgggc gcgtcgtacg
     3541 catcgtcggc gtcatggcga cagcctttcc gccgcagggg catcggtatc ttcggccccc
     3601 ggggcttcgg tcgcggcacg gtccgcgtcg gctccggtca ccacaccgtc cgcctcggct
     3661 tcggtcgcgg cacggtccgc cgccgccgtg acgaggtcga gcagcggcag cagctcggcc
     3721 gccgcggcgt ccgggtgcag cagtgtggcc ttcagccaga ggcggcgccg gccgtcgccg
     3781 tcctccgcct gcgcgcggcc gaggacggcg cgcccctcgg cgagcagggt gcggcggact
     3841 gcggcgacca cggcgtcgcc cgcctcgtcc ggcagcgcgt cggccaccgt cgggcggaac
     3901 agtacggtgc tgatcccgat gtcgccgggg cggcggcgca gtccggggcg ggtgtcgacg
     3961 gcccggccga actcgtgggc cgtgcgtacg cagtgctcca ccagttcgcc gagtccccgg
     4021 cgtccgagcg cccggaacgt gaccgccatc ttcagggcgt cggggcgccg ggtggtgcgg
     4081 atcgagcggc ccagcaggtc cgggagcccg gcctcggtgt cgtcgtcggc gttgaggtag
     4141 tcggcgcgca gcgacagcgg tgcgagcatc ccggcgtccg cgacggccag cactccggcg
     4201 gctaccggct gccagccgag tttgtgcagg tcgaacgtta cggaagcggc gtgctccagg
     4261 cccgcgagga gcggggcgag ccgttcgctg aacagcagcg gaccaccgta ggcggcatcg
     4321 acgtggagtc gggccgcgtg ccgctcggcg acgcgggcga tctccgggag cgggtcgatg
     4381 cgcccctcgt cggtggttcc ggcggtggcg acgaccagga gcggcgcccc ggcgagggag
     4441 gccagggcgt cgtcgagggc ggccgggtcg atccggccgt cgcggcaggc gacgaccacg
     4501 ggggcgggca gaccgagcat ccacgcggcg cggtggacgc tgtggtgggc gttggccccg
     4561 gtcaccaccc ggagggtgcc ggggacggct cgttcccggg cgagcagcag ggcgaccagg
     4621 ttggactcgg tgccgccgct ggtgatgagg gcgtcggggg cgggggccgt cgggtggatg
     4681 agccgggcca gtgcggccgt ggtcaactcc tcgatcaccc cggcggcggg tgcctggtcc
     4741 caggagtcca tggaggggtt gagggccgcc ccggccaggt ccgccgcgac ggccacggcg
     4801 agcggcgggc agtgcagatg ggcgacgcag gcggggtcgg ccggatcggc ggccccttcc
     4861 gcgaccgcgc ggaccacatc gccgagcgcg gcctcgggac cgacgccctc ctccggcagg
     4921 accggggcac agcgggcgag cgtgctcagg gccacgacct cgggcccccc ggcgggcagc
     4981 ggtccgcccc gggccggggc ggcgtcctcc agcgcgtcca ggacgatcgc ggtgagggcc
     5041 cgtagccgac ccggcccgtg cgcaccgccc gcgacgaggc cttcccgagg acccgccggg
     5101 cccggaatcg gcggcgtacc gtcgctcaca ccccacgctc cacggggagt tcgcaggacg
     5161 gcaggccctg agcacgcggc atggcgaagc ccttcggtcg gggtgcgcgg cggggtcgtg
     5221 cgggaggggc gcccgcgcgc ggggcggctc cggtcacgga aagatccaca accgggtatt
     5281 cgctggttag gctaacctaa ctcggaccgc gcgcaggaat ggcctccggc cggacgggcg
     5341 atccaccgac atccgaactg ccgttccgcc gaacgcagtc ggggcggacc ggcgccgggg
     5401 ttccgcgccg ggaggacgca ccgccggagc acagtcgcta cttcgcgtac cagccgccca
     5461 ggttgttcgt gcgcgactcc ccggcccgtc gcagcgcatc gggggttccc agcagttcgg
     5521 gcggcagata gccggagcgg aggccgagtt cccacccgtg cgcctgcacc gcgagcgcgg
     5581 ccagggcgag ggcgtggagc ggcagcaggg ttcggggcgc ggggtcgggg cccacgctcg
     5641 cgcggtggcc gacgagccgg gacgccaacg cctcctcgaa tgcggcctga tcgtcatcga
     5701 ggagcacacg aagaagccgc tggtccggtg tcagagcgcc cgaggcgtcc aacttcgctg
     5761 cggcgagcgc gagttcgtcg gcgtccggcc tgcggagggg aacggtgggc cagtgccggg
     5821 gctgatgccc ttcggcctcg gccagatagg ggcacagtgc gtccatcgcg gcgaggtccg
     5881 tcgggtccga ggccgagtcg agcttcgagt acggcacccc gtcgtggatc gcgggcgcgt
     5941 agtcgttccg cagcagcagt ccgatcaccc gctgccagtc ccatacgagc ccgctgacca
     6001 gggagaccgc gaacgcgtcg agccaggtac cggccgaggg ggcctgccct cccccgaagc
     6061 ggacgacgtc gccgaaggct atgtcctcgc tggtgagcgt ctcaccgatg agggggaagt
     6121 gcagctcctg gtcgccgtcg gggaagcacc cgacgctcat ctcccccagg tggcactccg
     6181 ccgccgtccg caacgccgaa cgcgcgacgt cgtcgagcag ggcgtcggcc gcgacacggg
     6241 cggccacgtg gtcgagcaac tcgtcggccg tctcacgcag ccgctcgggc gacgcgtcgt
     6301 cgtagcgcat cccgtgccac cgccccatgg tgcgcccgcc gatgccgctc agcgcctcgt
     6361 ccaggcgctg ggcacccacc tcatgacacg tcacttcccg cacgtccgcc gccctttcgt
     6421 gatcttcaag ccggaagcgg cacgctatca gcgggctcgg acattctcgg agccgtacgg
     6481 gcgggcccgg tgcgggagcg gtggccgccc ccgcaccggg ccgggtcacg ccgcttcggt
     6541 gggcagctcc gcgcggatct cccgcgccgc ggcgaccagg ttctccaggg aggcacgggt
     6601 ctcgggccag ccgcgggtct tcaggccgca gtcggggttc acccacagcc gtgacgccgg
     6661 gatggcctca agccccttgc gcagcagggc cgcggcctct tcggtgctgg ggatgcgcgg
     6721 ggagtggatg tcgtagacgc ccggtccggc ctcgcggggg tagccgtggg cggccagctc
     6781 gcgggcgacc tgcatatggg agcgggccgc ctccaggctg atgacgtcgg cgtcgaggtc
     6841 gtcgatggcc tggacgatgt cgccgaactc cgcgtagcac atgtgggtgt ggatctgggt
     6901 gtccggccgc actcctccgg tggcgagccg gaaggactcc gtcgcccact ccaggtacgc
     6961 ggcgtgctcg gcggcccgca gcggcagcgt ctcgcgcagc gcgggctcgt cgacctggat
     7021 caccgaagtg ccgctcgcct ccaggtcgtt cacctcgtcg cgcagggcga gggccacctg
     7081 ccgtgcggtg tcgccgagcg gctggtcgtc acggacgaag gaccaggcga gcatggtgac
     7141 cggtccggtg agcatgccct tgacggggcg tgcggtcagc gactgcgcgt acgtggtcca
     7201 gcgcaccgtc atcggttcgg ggcgcgagat gtcgcccgcg aggaccggcg gccgcacgta
     7261 ccgggtgccg taggactgca cccagccgtg ctgggtggcg aggtagccgg tgagctgctc
     7321 ggcgaagtac tggaccatgt cgttgcgttc gggctcgccg tgcaccagga cgtcgagccc
     7381 ggccttctcc tggaaggaga ggacctcgcg gatctcgtcc ttgatgcgct cctcgtagcc
     7441 ggcctcgtcg atccgccccg cacgcaggtc ggcgcgcgcg gtgcgcagtt cggtggtctg
     7501 cgggaacgag ccgatggtgg tcgtcggcag tagcggcagc ccgaggtggg cgcgctgggc
     7561 ggcggagcgc tcggtgtacg gctgggagcg gcggccgtcc gcgtcggtga cggccgccgt
     7621 gcgggcacgg acggccgggt cgcgggtgag cgcggcgccg gcgcgggagg ccaggtcggc
     7681 gcggttggcg gcgagttcgg ccgcgatggt gtccgtgccg ccggtcagtc cgcgggccag
     7741 gacgacgatc tcctcggtct tctgccgggc gaaggcgagc cagcgggcga tctgcgggtc
     7801 gatgtcgcgc tcggcgtccg cgtccagcgg gacgtgcagc agggagcagg aggcggagac
     7861 gtcgacccgg tcggcgaggc cgaggagggt gccgagggtg gcgagcgact tctcgtagtc
     7921 gttgatccag atgttgcggc cgttcacgac accggcgacc agccgcttgc cgggcaggcc
     7981 gccggccgcc gcgaggtcgt cgaggttccc cgcgccggac tcggtgaagt cgagggccaa
     8041 cccgtcgacg ggggccttgg ccagcaccgt cagtgcctcg ccgagccgcc cgaagtagga
     8101 ggcgaccagc agttggggcc ggtcggcgag gccgccgagc tcgcggtagg cgcgggcggc
     8161 ggcgttcagc tcggccgggg tgcggtcctg gacgagggcg ggctcgtcga gctgcaccca
     8221 tgcggcgccc gccgcgcgca ggtcggcgag gacctcggcg tacacgggaa gcagccggtc
     8281 cagcagggtc agcggttcga agtccgcggc cacaccgggg gccggcttgg cgagcaggag
     8341 gtaggtgacg gggccgacga gcaccgggcg cggggtgtgc ccgagcgcga gggcctccgc
     8401 gcattccgcg acctgcttgg cggagtcggc ggtgaacacc gtgtccggcc ccaactccgg
     8461 caccaggtag tggtagttgg tgtcgaacca cttcgtcatc tccagcgggg cgacgtcctg
     8521 cgtgccgcgg gccatggcga agtagccgtc gagggcgtcg gcgtcgaccg ccgcgcggtg
     8581 ccgcccgggg acggcgccga ccatgacgct ggtgtccagg acatggtcgt agtacgagaa
     8641 gtcaccggtc ggcacgtcgt ggacgccggc ctcggcgagc tgctgccagg tcccccggcg
     8701 cagctcggcg gcggtctccc ggagggcggc cgcgtcgacg cggcccttcc agtagccctc
     8761 gatggccttc ttcagttcac ggttcggacc ctggcggggg tagccgtaca cggtggcccg
     8821 tgctgccgcg gctgcgggct tcgctgtcac gtgactctcc ttcgcgagcg tgtctgcatg
     8881 acagaccccg ggacgggacg cggacgcgaa gggatgacgc gtcgggcgga catcgggaca
     8941 cgtcgaaccg tgtccgtcca cctgacggtt acgccgaccc gcccacgagg tcaccgagat
     9001 ctccgcacgc gaacggtcgc gtgcgggcag cgggcaggtc ttcggactcg cgggcacgtc
     9061 tgccgggcag acacctagtg gccgtcgctt cccagacccg tccgggccca gtgcgtatga
     9121 cggcggtcgt tcccactcac cgctgcgggg cagtcccgga tttccaccgg gttccctctt
     9181 gcgacaccct gcctggcgga cagggcgaac cagctgcacc ggtcagccta aggggacgcc
     9241 cggcccgcgc acaccgtagt tcacacttcg gacggtgacg tgggacacgg ccgagcgcat
     9301 gccgacttcg gttcgggctc cccggcgatg cccgccgcat cgcgccacac gttttctccg
     9361 cccgttcgac tgttcgtcag catcctgctg accaccagtc aggtcgggcg cgtccactgg
     9421 acgtgacagt gacacagatg taaccgaatg gcgtagggac tgcggaacca ccgagcgtca
     9481 caagccgttc ttcttcccac tacacggccg ccgacccgcg gcgaggccga ccgaggaaac
     9541 ggaaaacgcc agatgaagaa gacagtcggg tgggcccagg acggcgacga ctggacgatc
     9601 accgtgaacg gcacgctgta ccgcgccgtc gaacggccga cggacggccg cgtgcacaac
     9661 tacctggtgc acggcagcga tctgaccgcc gaatgcccca gcctgggaca cgggctcggt
     9721 gtcatccggg cgcacgagtc ccggggctga cactccccca ggtccgacga cgaggtgcgg
     9781 cggccggggc cgcccgcgcc tcgacgcgga cctttcagcg gttcgtacgg tccgcgtcgc
     9841 ccgtgccatc cgctccgacc gcagcgtccg tgtcgcccgg ccctcggcgc agcagatagg
     9901 tgtccatgat ccagccgtgc cgttcgcggg cctccgcgcg cagccggctg atccggcccg
     9961 ccacctcgtc gagcggcccg gagaccagga tctcgtccgg ggtcccgata taggcgcccc
    10021 agtggatcc
//
