LOCUS       BGC0000252             15559 bp    DNA     linear   BCT 15-FEB-2000
DEFINITION  Streptomyces griseus subsp. griseus nonactin biosynthesis gene
            cluster, partial sequence.
ACCESSION   BGC0000252
VERSION     BGC0000252
KEYWORDS    .
SOURCE      Streptomyces griseus subsp. griseus
  ORGANISM  Streptomyces griseus subsp. griseus
            Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
            Streptomyces.
COMMENT     On Jun 7, 1999 this sequence version replaced AF074603.1.
            ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2022-11-07 17:55:49
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15559
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..15559
                     /db_xref="taxon:67263"
                     /mol_type="genomic DNA"
                     /note="upstream of macrotetrolide resistance gene"
                     /organism="Streptomyces griseus subsp. griseus"
                     /strain="ETH A7796"
                     /sub_species="griseus"
     subregion       1..15559
                     /aStool="mibig"
                     /contig_edge="True"
                     /label="Polyketide"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..15559
                     /contig_edge="True"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            249..1526
                     /gene="nonK"
     CDS             249..1526
                     /NRPS_PKS="Domain: PKS_KS(Trans-AT-KS) (146-390). E-value:
                     2.9e-19. Score: 61.1. Matches aSDomain:
                     nrpspksdomains_nonK_PKS_KS.1"
                     /codon_start=1
                     /gene="nonK"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) t2fas"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 171.1; E-value:
                     6.8e-52)"
                     /gene_kind="biosynthetic-additional"
                     /note="ketoacyl synthase I homolog"
                     /product="NonK"
                     /protein_id="AAD37450.1"
                     /sec_met_domain="t2fas (E-value: 3.3e-44, bitscore: 141.1,
                     seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGFCLPGAGDEPVRTAEQVWAAASTGTSHVERDGFHHGTVRGARE
                     AFGELLPDIPARYLRSYADVHLYGLISLAEACRDAGLDYGKGELRGADVLTARAGVDSN
                     YDSYRAWHDADPATVTPSDAKSLFVRLLVAGTSSDVGPVQAALLGSTGANYTVSCGCAS
                     SSVLLGIARMMIASGQSDLVVVTGVDRFDTERVLHGHRLREVVEREGVTVRHNSDPPAA
                     PRHDRPMRPYDAAGDCMNYGDGSVTLILESREHAAARGARTHGAVLGQATTRGGLNSAV
                     AIDTGGTGLAEAARRALGDHTSLGRIPYVNGGGEGDALFTRIESNAVRALWGDRSEQVL
                     VSSQEACFGHSGAPLGNLGTALTLMMMREGEVCPTANCATPSPVCTFDPVPGTRTRALG
                     FDRALSFNYQVGGVNSALLLGGGDVC"
     aSDomain        687..1418
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_nonK_PKS_KS.1"
                     /domain_subtype="Trans-AT-KS"
                     /evalue="2.90E-19"
                     /label="nonK_PKS_KS.1"
                     /locus_tag="nonK"
                     /protein_end="390"
                     /protein_start="146"
                     /score="61.1"
                     /tool="antismash"
                     /translation="LLGSTGANYTVSCGCASSSVLLGIARMMIASGQSDLVVVTGVDRF
                     DTERVLHGHRLREVVEREGVTVRHNSDPPAAPRHDRPMRPYDAAGDCMNYGDGSVTLIL
                     ESREHAAARGARTHGAVLGQATTRGGLNSAVAIDTGGTGLAEAARRALGDHTSLGRIPY
                     VNGGGEGDALFTRIESNAVRALWGDRSEQVLVSSQEACFGHSGAPLGNLGTALTLMMMR
                     EGEVCPTANCATPSPVCTFDPV"
     gene            1516..2796
                     /gene="nonJ"
     CDS             1516..2796
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (86-378). E-value:
                     8.3e-14. Score: 43.1. Matches aSDomain:
                     nrpspksdomains_nonJ_PKS_KS.1"
                     /codon_start=1
                     /gene="nonJ"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) t2ks"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 175; E-value:
                     4.2e-53)"
                     /gene_kind="biosynthetic-additional"
                     /note="ketoacyl synthase II homolog"
                     /product="NonJ"
                     /protein_id="AAD37451.1"
                     /sec_met_domain="t2ks (E-value: 2.5e-22, bitscore: 69.2,
                     seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAELPLLRLSGAGFVLPGPDGRACTDLDTFWGVVRDGASCLSPY
                     AHPELPLRIAGTVNGWDPETELPLSERQIRRSSRAGLMATGAVHRALEHAGLSADDLDP
                     GRTALVACSLQFAFPETERYYALARDEGVAALGMEYWLNGTPPSVVGTVASGLRLPCQT
                     LSVAGSCNVALRTLHLVQQMFRCGDIDRAIVVGVDTTVDPVFVAGTSHTGRSGYRASSL
                     SDDPADVRPHDEIQTGNATGEGALAVVLENPAATGDRPGLLHRAHLRTSRSNGPSTVAT
                     GPPANVVGDVLATLASARRGLGDLAFVNDYADGNRFVEDHLCQALAGVKEAAGYGGELR
                     LTNQEAVFGHVAGTGGLVKLLGSLLMLRHGHIAPSANTLVPYAGLPGDPVLAGGLATGG
                     DSALVLASGAGGDATSMVIEYEGGDLP"
     aSDomain        1774..2649
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_nonJ_PKS_KS.1"
                     /domain_subtype="Hybrid-KS"
                     /evalue="8.30E-14"
                     /label="nonJ_PKS_KS.1"
                     /locus_tag="nonJ"
                     /protein_end="378"
                     /protein_start="86"
                     /score="43.1"
                     /tool="antismash"
                     /translation="AVHRALEHAGLSADDLDPGRTALVACSLQFAFPETERYYALARDE
                     GVAALGMEYWLNGTPPSVVGTVASGLRLPCQTLSVAGSCNVALRTLHLVQQMFRCGDID
                     RAIVVGVDTTVDPVFVAGTSHTGRSGYRASSLSDDPADVRPHDEIQTGNATGEGALAVV
                     LENPAATGDRPGLLHRAHLRTSRSNGPSTVATGPPANVVGDVLATLASARRGLGDLAFV
                     NDYADGNRFVEDHLCQALAGVKEAAGYGGELRLTNQEAVFGHVAGTGGLVKLLGSLLML
                     RHGHIAPSANT"
     gene            2793..4394
                     /gene="nonM"
     CDS             2793..4394
                     /NRPS_PKS="Domain: PKS_KR (264-423). E-value: 3.4e-10.
                     Score: 31.9. Matches aSDomain:
                     nrpspksdomains_nonM_PKS_KR.1"
                     /codon_start=1
                     /gene="nonM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     169.4; E-value: 1.7e-51)"
                     /gene_kind="biosynthetic-additional"
                     /note="NonM"
                     /product="putative ketoacyl reductase"
                     /protein_id="AAD37452.1"
                     /transl_table=11
                     /translation="MTHVHSTATRPGTAAGGDPSRAPVSTRVVVDAAGGDGPAAGALSD
                     ALTALGLAPEAPDTEAPDTGRADSGDPAPAAYCALLLGEEAYGAGRSAGLDRSRVRAAA
                     LAIAAAGRGRLVLVTDATGETHAGTDPDRYARLAADRAWWQHLVTEVAGRGVTGNTVVT
                     GYSPGLGHRLSAEAEAGLLRCLVQRRPTTAADVAATVAFLVSEGCSYLVGETLPVDGGA
                     GLGQIPSLPAGPPTTAPAPRRGAPREQPPPEPVSGQDLLGHKVLVAGASSGIGRAAALH
                     LAGRGADVILAARRTQALEEVAAEIEARGRQAWTLRCDLSDAEDAASLGERAWKAADGV
                     TALLYAAGHLGFSAVGGDPASAARTFAVNLHSFVAVTEYLAARWRDERMPGAVVGVSSV
                     SSTLSPVAGLEYYGASKAAMAQYIRCLAVSVGRHGIRANCVAPGIIETPMGDAAGPDHR
                     RGWISRIPAGRVGDPHEVAAVLGYLLSGSASRVTGAVLRADGGFGLGDVAPLRPGYPER
                     AFPAPALPERAEGENR"
     CDS_motif       3096..3146
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_nonM_0001"
                     /evalue="2.20E+00"
                     /label="PKSI-KR_m1"
                     /locus_tag="nonM"
                     /protein_end="118"
                     /protein_start="101"
                     /score="1.1"
                     /tool="antismash"
                     /translation="AAALAIAAAGRGRLVLV"
     aSDomain        3585..4061
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_nonM_PKS_KR.1"
                     /evalue="3.40E-10"
                     /label="nonM_PKS_KR.1"
                     /locus_tag="nonM"
                     /protein_end="423"
                     /protein_start="264"
                     /score="31.9"
                     /tool="antismash"
                     /translation="VLVAGASSGIGRAAALHLAGRGADVILAARRTQALEEVAAEIEAR
                     GRQAWTLRCDLSDAEDAASLGERAWKAADGVTALLYAAGHLGFSAVGGDPASAARTFAV
                     NLHSFVAVTEYLAARWRDERMPGAVVGVSSVSSTLSPVAGLEYYGASKAAMAQYI"
     CDS_motif       3588..3674
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_nonM_0002"
                     /evalue="3.50E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="nonM"
                     /protein_end="294"
                     /protein_start="265"
                     /score="13.3"
                     /tool="antismash"
                     /translation="LVAGASSGIGRAAALHLAGRGADVILAAR"
     gene            4391..5206
                     /gene="nonE"
     CDS             4391..5206
                     /NRPS_PKS="Domain: PKS_KR (11-120). E-value: 9.1e-10.
                     Score: 30.5. Matches aSDomain:
                     nrpspksdomains_nonE_PKS_KR.1"
                     /codon_start=1
                     /gene="nonE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     175.4; E-value: 2.5e-53)"
                     /gene_kind="biosynthetic-additional"
                     /note="NonE"
                     /product="putative ketoacyl reductase"
                     /protein_id="AAD37453.1"
                     /sec_met_domain="adh_short (E-value: 3.4e-32, bitscore:
                     101.8, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATAQAGRHPVALVAGASSGIGAAVARRLAARGSAVALVGRREP
                     ELKEVAESIRAAGGTALSLALDLAGPGAPAEAVAATAAGLGPVGLLVCSAGAIRLAAVH
                     ETEERHWERQLRVNLTVPFLLAREVLPGMRERGFGWVVNIGSGVGSEVVPGSGGYGVSK
                     HTVHRLTELIHEENRDLGIRAVTVAPGWVSTRLAARPADLGVPEEEVLDAEDIADTVAW
                     LLDRPARMSVGPLVRVEPSASRAAAGDAMTRHLTRSRAEGAGPDAEETR"
     aSDomain        4424..4750
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_nonE_PKS_KR.1"
                     /evalue="9.10E-10"
                     /label="nonE_PKS_KR.1"
                     /locus_tag="nonE"
                     /protein_end="120"
                     /protein_start="11"
                     /score="30.5"
                     /tool="antismash"
                     /translation="VALVAGASSGIGAAVARRLAARGSAVALVGRREPELKEVAESIRA
                     AGGTALSLALDLAGPGAPAEAVAATAAGLGPVGLLVCSAGAIRLAAVHETEERHWERQL
                     RVNLT"
     gene            5206..6915
                     /gene="nonD"
     CDS             5206..6915
                     /codon_start=1
                     /function="speculated to cleave linear nonactic acid
                     oligomers as part of a resistance/salvage pathway"
                     /gene="nonD"
                     /note="similar to glutaryl 7ACA acylase; ORFD; NonD"
                     /product="putative diester hydrolase"
                     /protein_id="AAC26133.1"
                     /transl_table=11
                     /translation="MGRTTLIEHDVPVEMRDGTVLRADVWRPAEGPASPAVLFRTPYGK
                     SPLGLATLTPAQCVDRGYAAVVQDTRGRFGSEGEWAPLDWSQEGPDGYDTVEWTAEQPW
                     CDGNVAMAGTSYQAIVQWLAAMEKPPHLRAIAPTMSTSAPFDAEQLGGFLRLDHLTSWL
                     GLTALEWVQRRAAAGDPVDGAVVAEVVQLLTAPEVPLRRWPLSTILDFEGFPGRLRDIF
                     AGHVATVADYHLGEVGVPTFSVGGWYDVFSHGTIELHRAVRALDPVAGRHELVVGPWVH
                     SGQLPQVQGEVNTGPYGSAQGARLADLHLDFFDRHLRPAGGTTGRDSGGDVRYFLFGDD
                     AWHRAASWPPPEAVDAPWYLAGPADGEEGGRLLPAPPREAPGHDAFTYDPEDPVPSHGG
                     RVLQLGRLAAGPLNQAHLEDRPDVLCYTSEPLTEPLDAVGRQRLRLRFGSDAPATAVVA
                     KLTDVHPDGRSLLVAEASLRLEAEGDGPRDEPYDADLLLGDTAWRFAPGHRLRVHVTSS
                     NFPHLDRHPNIPGPVGEAEHCRTARQSVWYGGPYESVLRLSTLPAPSAGETA"
     gene            6912..8579
                     /gene="nonL"
     CDS             6912..8579
                     /NRPS_PKS="Domain: AMP-binding (25-440). E-value: 1.8e-76.
                     Score: 249.1. Matches aSDomain:
                     nrpspksdomains_nonL_AMP-binding.1"
                     /codon_start=1
                     /gene="nonL"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     308.8; E-value: 9.5e-94)"
                     /gene_kind="biosynthetic-additional"
                     /note="similar to CoA-ligase; ORFL; NonL"
                     /product="putative nonactic acid:CoASH ligase"
                     /protein_id="AAC26134.1"
                     /sec_met_domain="AMP-binding (E-value: 8.1e-88, bitscore:
                     284.5, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIDDVLDPASAAVPTAEQCVLGPLLRRRAAAAPAAPYALMPDGDL
                     WTYARTLRETEETAAALQALGVVPGELVLSWLPNGPDALRAWYGVNLAGAVLVPLNIAY
                     RGAILRQVIADSGAEVLICRPSLAARLEDSDDAVGAVRTVVLLPGPEDAAQDVEALAGR
                     LATRFRVETALRADRAEFAEPVPAPRPWDPQTVIYTSGTTGPSKGVVSSYAHLYSSCTA
                     AFHGMAGPEDRYLLQLPLFHAGGTIGAYGMLVHGGSVTVVPAFTTGEFWPLIRRTGTTL
                     CTLLGVMATYLLKQPPLPQDTAHPLRAAYVIPFTEGATEFSKRFGVPVRALFNMTEVSC
                     PVLSAPDHHPGVPMHCGEPRPGIAARVVDDHDREVADGEAGELVLRADRPWSFLSGYLG
                     RPAETAAVWRNGWFHTGDTFRRAPDGGLVFVDRKKDAIRRRGENISSFEVEAQAVAHPG
                     VLEAAAVAVPGDEGEDEVLLVVADRDPSAPVDPAALLEFLRERLAHFMLPRYIRVLPEL
                     PKTPTGKPTKHTLRAEGVVAGTWDREAAGIRIRREKIV"
     aSDomain        6987..8231
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_nonL_AMP-binding.1"
                     /evalue="1.80E-76"
                     /label="nonL_AMP-binding.1"
                     /locus_tag="nonL"
                     /protein_end="440"
                     /protein_start="25"
                     /score="249.1"
                     /tool="antismash"
                     /translation="RRRAAAAPAAPYALMPDGDLWTYARTLRETEETAAALQALGVVPG
                     ELVLSWLPNGPDALRAWYGVNLAGAVLVPLNIAYRGAILRQVIADSGAEVLICRPSLAA
                     RLEDSDDAVGAVRTVVLLPGPEDAAQDVEALAGRLATRFRVETALRADRAEFAEPVPAP
                     RPWDPQTVIYTSGTTGPSKGVVSSYAHLYSSCTAAFHGMAGPEDRYLLQLPLFHAGGTI
                     GAYGMLVHGGSVTVVPAFTTGEFWPLIRRTGTTLCTLLGVMATYLLKQPPLPQDTAHPL
                     RAAYVIPFTEGATEFSKRFGVPVRALFNMTEVSCPVLSAPDHHPGVPMHCGEPRPGIAA
                     RVVDDHDREVADGEAGELVLRADRPWSFLSGYLGRPAETAAVWRNGWFHTGDTFRRAPD
                     GGLVFVDRKKDAIRRR"
     CDS_motif       7497..7544
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_nonL_0001"
                     /evalue="3.00E-05"
                     /label="NRPS-A_a3"
                     /locus_tag="nonL"
                     /protein_end="211"
                     /protein_start="195"
                     /score="16.8"
                     /tool="antismash"
                     /translation="VIYTSGTTGPSKGVVS"
     CDS_motif       7842..7880
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_nonL_0002"
                     /evalue="2.70E+01"
                     /label="NRPS-A_a3"
                     /locus_tag="nonL"
                     /protein_end="323"
                     /protein_start="310"
                     /score="-1.3"
                     /tool="antismash"
                     /translation="VIPFTEGATEFSK"
     CDS_motif       8040..8132
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_nonL_0003"
                     /evalue="3.10E-03"
                     /label="NRPS-A_a6"
                     /locus_tag="nonL"
                     /protein_end="407"
                     /protein_start="376"
                     /score="10.0"
                     /tool="antismash"
                     /translation="DGEAGELVLRADRPWSFLSGYLGRPAETAAV"
     gene            8576..9469
                     /gene="nonS"
     CDS             8576..9469
                     /NRPS_PKS="Domain: ECH (42-289). E-value: 2e-37. Score:
                     120.6. Matches aSDomain: nrpspksdomains_nonS_ECH.1"
                     /codon_start=1
                     /function="catalyzes the formation of the furan ring of
                     nonactic acid from an acyclic precursor"
                     /gene="nonS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023:enoyl-CoA hydratase (Score: 166; E-value:
                     1.4e-50)"
                     /gene_kind="biosynthetic-additional"
                     /note="enoyl-CoA hydratase homolog; ORFX"
                     /product="nonactate synthase"
                     /protein_id="AAC26135.1"
                     /transl_table=11
                     /translation="MNQEAFRAGQEPPAEWAGAATESFADFADRVDGKEVVPLRASLAG
                     GVATLTLDRPHRRNSLDLTLSRHLLLGLMCAGDDPRVRTVVITGNGGAFCAGDDVGSVR
                     RWRLGDRADTPFDPITSDAHYLRVCEAILHLPKPVVVGLTGAAAGAGAEIACAADFRLA
                     DTRASIGSCLAGVGHVGNVVLMSRLTGPARATEIYLTGRMVSGDEAVRLGLFDRLCEPE
                     DFDRELADLAGRFAALPTASVGLFKELRERSWGQPAEYGLRLQDTYHLKTHATVADARE
                     GMAAFTEKRPPRFTGA"
     aSDomain        8702..9442
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_nonS_ECH.1"
                     /evalue="2.00E-37"
                     /label="nonS_ECH.1"
                     /locus_tag="nonS"
                     /protein_end="289"
                     /protein_start="42"
                     /score="120.6"
                     /tool="antismash"
                     /translation="LAGGVATLTLDRPHRRNSLDLTLSRHLLLGLMCAGDDPRVRTVVI
                     TGNGGAFCAGDDVGSVRRWRLGDRADTPFDPITSDAHYLRVCEAILHLPKPVVVGLTGA
                     AAGAGAEIACAADFRLADTRASIGSCLAGVGHVGNVVLMSRLTGPARATEIYLTGRMVS
                     GDEAVRLGLFDRLCEPEDFDRELADLAGRFAALPTASVGLFKELRERSWGQPAEYGLRL
                     QDTYHLKTHATVADAREGMAAFTEK"
     gene            9705..10544
                     /gene="nonR"
     CDS             9705..10544
                     /codon_start=1
                     /gene="nonR"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036:alpha/beta hydrolase fold protein (Score: 100.3;
                     E-value: 2.6e-30)"
                     /gene_kind="biosynthetic-additional"
                     /note="NonR"
                     /product="tetranactin resistance protein"
                     /protein_id="AAD37454.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 2.3e-23, bitscore:
                     73.8, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 5.1e-19, bitscore: 58.7,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGPDGRTVTGARVEETAHSIDVSGARLHYWTAGAADRPGIALTH
                     GAGADHRMFDPQIPALVGAGYRTLRWDVRYHGASVSGTGRFRTVYAARDLAALLDAAGM
                     PRPVVLLGQSMGGNIAQEYLRRRPDEVAALVVIGSTSNTLPITRAERRGLAFSRAFMRL
                     MPYRRLTRSMARASAEDPGARTYLRETFLANGRRSFLTTWDGMTRAIDPSPDYRVEKPE
                     LLLCGEHDSTGNIRSAMERWSERDPHSEFHVIPGAGHVANLDRPDEVNRLTVAFLKA"
     gene            10560..11066
                     /gene="nonB"
     CDS             10560..11066
                     /codon_start=1
                     /gene="nonB"
                     /product="NonB"
                     /protein_id="AAD37455.1"
                     /transl_table=11
                     /translation="MTDHDITPDAGPLPMPGSDGFSDAEAAFISEMGSLMERWGLPQAT
                     GRLFGYLLLRNKPVDLDTMTRELGQAKSGLSVAARQLEAWSLVRRSTRAGSRRIDYEAV
                     GDLQHLLLVNNAHMRKFTETLSSGIPVARGEARDRLASLAGLFNGYVEQTEALVAAWEA
                     RRAAT"
     gene            11255..12208
                     /gene="nonC"
     CDS             11255..12208
                     /codon_start=1
                     /gene="nonC"
                     /product="NonC"
                     /protein_id="AAD37456.1"
                     /transl_table=11
                     /translation="MDACSLVYDDAGWRAYLNRLGENAPEYLDVFSASFCRYFGASHTA
                     YRDALAVRRQDAIDVLLPPDRPPFDLAGHLADRERQGVTGEFAMGSAERLPDGRTVNEW
                     LLETVRDVRDRIHVWAGISLRDPAAALRELERSLAAGATGLCVIPFLDGTDPADPRFAP
                     VWDAAAEARLPVWLHTGHHFARSHPSGLGSWRTVETLAGRHRALLLVAGHAGWPDVQEM
                     LLTAARHPGVFLEFSSHRPRHMSKPGSGWEPLLHHARGMARDRVMFGTSTWVNPGPTGP
                     LADELAALPLPADVVAAWLSGNAEALVARAAGTHRG"
     gene            12384..13088
                     /gene="nonF"
     CDS             12384..13088
                     /codon_start=1
                     /gene="nonF"
                     /product="NonF"
                     /protein_id="AAD37457.1"
                     /transl_table=11
                     /translation="MYDMAKILFVVSGADHWTLADGTAHPTGFWAEEAVAPYRAFTDAG
                     HEVVVATPGGVVPTVDRGSLAPDVNGGQEGADAVAAGLEAFEELRRPVALEDVDPDVYD
                     AVFYPGGHGPMEDLAVDPVSGRLLARVLASGKPLGVVCHGPAALLAATGPDGRSAFAGY
                     RLTGFTNAEEAQAGFADKAKWLLQDRLVALGADFQEGEPWAPFVITDRNLITGQNPASS
                     VPLAAELLNRLG"
     gene            13237..13599
                     /gene="nonI"
     CDS             13237..13599
                     /codon_start=1
                     /gene="nonI"
                     /note="NonI"
                     /product="putative acetoacetate reductase"
                     /protein_id="AAD37458.1"
                     /transl_table=11
                     /translation="MRSRPHDLAAEDEPFREPHQGLVARSLGIAVDHGGPDDHAVAGGA
                     FGLQFARRAHRAQQPPERGGAAPAAAIVGEAALLVRLLDGAHCCLGHGSTPCARLGRAA
                     PALRARPHHMALSAGP"
     gene            complement(13623..14351)
                     /gene="nonG"
     CDS             complement(13623..14351)
                     /codon_start=1
                     /gene="nonG"
                     /gene_functions="regulatory (smcogs) SMCOG1215:TetR family
                     transcriptional regulator (Score: 198.3; E-value: 2.4e-60)"
                     /gene_kind="regulatory"
                     /note="NonG"
                     /product="putative transcriptional repressor"
                     /protein_id="AAD37459.1"
                     /transl_table=11
                     /translation="MSEARGSEKKAPMREVLAQAAFRLFLERGFERTTVDDIVALAGVG
                     RRSFFRYFPSKEDAVFPDHERCLAETTEFLAAVDDSDPVGAVCDAARIVLRMYAANPEF
                     SVQRYRLTREVPGLRTYELSVVRRYEQTLAGHLRGRFGEGRDGELRAEVIAASVVAAHN
                     NGLRLWLRSGGAGDPEAAVDHALALVREVWGRPAVPTPATPFPVSGGGDGKGEVIVMVA
                     RKGTPMWRVVQQIEAAVGEN"
     gene            14440..15270
                     /gene="nonH"
     CDS             14440..15270
                     /codon_start=1
                     /gene="nonH"
                     /note="NonH"
                     /product="putative flavoprotein reductase"
                     /protein_id="AAD37460.1"
                     /transl_table=11
                     /translation="MTPRWDHTQVGRRAGVSLRIVVCVKYVPDATGDRRFADDLTLDRE
                     DVDGLLSELDEYAVEQALQIADGADDAEITVVTVGPEDAKDALRKALSMGADKAVHVED
                     DDLHGSDVMGTSLVLAKAVEKAGYDLVICGMASTDGVMGVLPALLAERLGVPQVTLLSE
                     VAVDGGVVTGRRDGDTASEQLEASLPAVVSVTDQSGEARYPSFKGIMAAKKKPVESLDL
                     DDLGLDADEVGLAGAWTVVDSATERPARTAGTIVKDEGEGGRQLAGFLAGQKFI"
ORIGIN
        1 ctcaggcgcg cggtcaacag caccatcctg cggcgcctgg tgcgccccga ggagatcgcc
       61 gcccaggtcc tgttcctgct ctccgacctc tccggcggga tgaccggaca ggccgtcaac
      121 gtggacgcgg gggctctgtg agcaaggagc acggcccggg gaagggcgaa ccgcccctgc
      181 cggaacagct gctcgccccc gcggcgcgcc cctgggcccc cggcccccgg gacgcgctgg
      241 tcaccgggat ggggttctgc ctgcccggtg cgggcgacga gccggtgcgc acggccgagc
      301 aggtctgggc ggccgcctcc accgggacca gtcatgtcga acgcgacggc ttccaccacg
      361 ggaccgtacg cggtgcccgc gaggcgttcg gagagctgct gccggacata ccggcccgct
      421 atctgcgcag ctacgccgac gtccacctct acgggctgat ctcgctggcc gaggcctgcc
      481 gggacgccgg actcgattac gggaaaggcg agttgagagg ggcggacgtg ctgaccgccc
      541 gggccggggt ggacagcaac tacgacagct accgcgcctg gcacgacgcc gatccggcga
      601 cggtcactcc ctcggacgcc aagtccctct tcgtacggct cctggtggcg ggcacctcca
      661 gcgacgtcgg ccccgtccag gccgcgctgc tcggttccac cggcgccaac tacacggtga
      721 gctgcggctg cgcctcctcc tcggtgctgc tcggcatcgc ccgcatgatg atcgcctccg
      781 gccagagcga cctggtcgtg gtcaccgggg tggaccgctt cgacaccgaa cgggtgctgc
      841 acggacaccg gttgcgcgag gtcgtcgagc gcgagggcgt gacggtgcgg cacaacagcg
      901 atccgccggc agcaccccgt cacgaccggc cgatgcgccc gtacgacgcg gcgggcgact
      961 gcatgaacta cggcgacggg tcggtgaccc tgatcctgga gagccgcgaa cacgccgccg
     1021 cgcggggcgc ccggacgcac ggggcggtcc tcggccaggc caccacgcgc gggggcctga
     1081 acagcgccgt cgccatcgac accggcggta cggggctggc cgaagcggcc cgccgcgccc
     1141 tgggcgacca tacctcgctg gggcggatcc cctacgtcaa cgggggcggc gagggcgacg
     1201 cgctgttcac ccggatcgag tccaacgccg tccgcgccct gtggggcgac cggtccgagc
     1261 aggtgctggt gagttcgcag gaggcgtgct tcgggcacag cggcgcgccg ctcggcaatc
     1321 tgggcacggc gctgacgctg atgatgatgc gcgagggaga ggtctgcccc acggccaact
     1381 gcgcgacccc gtcgcccgtc tgcacattcg acccggtccc cggcaccagg acgcgtgcgc
     1441 tgggcttcga ccgggccctg agcttcaact accaggtggg cggggtcaac agcgcactgc
     1501 tgctgggagg tggcgatgtc tgctgagctg cctctgctgc ggctttccgg cgccgggttc
     1561 gtcctgccgg ggccggacgg ccgcgcctgc accgacctgg acaccttctg gggtgtggtg
     1621 cgcgacgggg cgagctgcct ctccccgtac gcccatcccg aactccccct ccgtatcgcc
     1681 gggaccgtga acggctggga cccggagacc gaactcccgc tgtcggaacg gcagatacgc
     1741 cgttcctcgc gcgccgggct gatggccacg ggtgcggtgc accgggcgct ggagcacgcc
     1801 gggctgagcg cggacgacct cgatccgggg cgtaccgcgc tcgtcgcctg ctcgctccag
     1861 ttcgcgttcc cggagaccga gcgctactac gccctggccc gggacgaggg ggtcgccgcc
     1921 ctcggcatgg agtactggct caacgggacc ccgcccagtg tggtgggcac cgtggcctcc
     1981 ggcctccggc tgccctgcca gacgctgagc gtggcgggct cctgcaatgt ggcgctgcgg
     2041 acgctccacc tcgtccagca gatgttccgg tgcggggaca tcgaccgcgc gatcgtcgtc
     2101 ggcgtggaca ccacggtgga cccggtcttc gtggcaggca ccagccacac cggacgcagc
     2161 ggctaccgcg cgtcctcgct ctccgacgac cccgccgacg tccggccgca cgacgagatc
     2221 cagaccggca acgccaccgg ggagggcgcg ctcgccgtgg tgctggaaaa cccggcggcg
     2281 accggggacc gcccggggct gctgcaccgc gcgcatctgc gcacctcgcg ctccaacggc
     2341 ccctccaccg tggccaccgg accgcccgcc aacgtggtgg gcgacgtact ggccacgctg
     2401 gcttcggccc ggcgcggcct gggcgatctg gcgttcgtca acgactacgc ggacggcaac
     2461 cggttcgtcg aggaccacct gtgccaggcg ctcgccgggg tgaaggaggc ggccgggtac
     2521 ggcggggagc tgcggctcac caaccaggag gcggtcttcg ggcatgtcgc cggaaccggc
     2581 ggcctggtca aactcctcgg cagcctcctc atgctgcgcc acggccatat cgcccccagc
     2641 gccaacaccc tggtcccgta cgcgggtctg ccgggcgacc cggtgctcgc gggcggcctg
     2701 gcgaccggcg gagacagcgc gctggtgctc gcctccgggg cgggcggcga cgccacgagc
     2761 atggtcatcg aatacgaagg cggcgacttg ccatgaccca cgttcacagc acggcgacgc
     2821 ggcccgggac ggccgcggga ggggacccgt cgcgggcgcc ggtcagcacc cgcgtggtcg
     2881 tcgacgccgc cgggggcgac ggtcctgccg ccggggccct ctccgacgcg ctcaccgcgc
     2941 tcggcctcgc ccccgaggcc ccggacaccg aggccccgga caccggccgc gccgattccg
     3001 gcgaccccgc cccggccgcc tactgcgctc tgctgctcgg cgaggaggcg tacggcgccg
     3061 gacgctcggc gggcctggac cgctcacgcg tccgggccgc cgcgctggcg attgcggcgg
     3121 cgggccgggg acggctcgtc ctggtgaccg acgcgacggg cgagacccac gccggaaccg
     3181 accccgaccg gtacgcgcgg ctcgccgccg accgggcctg gtggcagcac ctggtcaccg
     3241 aggtggccgg gcgcggcgtc accggcaaca ccgtggtcac gggctactcc cccggcctgg
     3301 gccaccggct gtccgccgag gccgaggccg ggctgctgcg ctgtctcgtg cagcgccggc
     3361 ccaccacggc cgccgatgtc gcggccaccg tcgccttcct ggtctccgag gggtgttcgt
     3421 acctggtcgg cgagactctg ccggtcgacg ggggcgcggg cctcggccag atcccgtccc
     3481 tgcccgccgg cccgccgacg acggcccccg caccgcgccg cggtgctccg cgggagcagc
     3541 cgccgccgga gccggtgagc ggtcaggacc tcctgggcca caaggtcctg gtggcgggcg
     3601 cgagcagcgg catcggccgg gccgcggccc tgcacctggc cggacgcggg gccgacgtga
     3661 tcctggccgc ccgccggacg caggcgctgg aggaggtggc cgccgagatc gaggcccggg
     3721 gccggcaggc ctggaccctg cgctgcgacc tctccgacgc cgaggacgcc gcttctctgg
     3781 gcgaacgggc ctggaaggcg gccgacggcg tcaccgccct gctgtacgcg gcggggcacc
     3841 tgggcttcag cgcggtcggc ggcgaccccg cttccgccgc ccggaccttc gcggtgaacc
     3901 tgcacagctt cgtcgccgtc accgagtacc tggcggcccg ctggcgggac gagaggatgc
     3961 ccggagcggt ggtcggggtc tcctcggtca gctccacgct cagcccggtg gcgggcctgg
     4021 agtactacgg ggcgagcaag gccgcgatgg cgcagtacat ccgctgtctc gcggtctcgg
     4081 tgggccgcca cggcatccgc gccaactgcg tggctcccgg catcatcgag acgccgatgg
     4141 gcgacgcggc ggggcccgac caccggcgcg gctggatcag ccggataccg gccgggcggg
     4201 tcggcgaccc gcacgaggtg gcggcggtcc tcggctatct gctgagcggt tcggcctccc
     4261 gggtgaccgg tgccgtgctg cgcgcggacg gcggcttcgg cctcggtgac gtggctccgc
     4321 tgcggccggg atacccggag cgggccttcc ctgcaccggc gctcccggag cgggcggagg
     4381 gggagaaccg atgaccgcca ccgcgcaagc aggccgccac ccggtcgccc tcgtcgccgg
     4441 cgcctcctcc gggatcgggg ccgccgtcgc ccgccgactg gccgcgcgcg gcagcgccgt
     4501 ggcgctggtc gggcggcggg agcccgagct gaaggaggtc gcggagtcga tccgcgcggc
     4561 cggcggaacc gcgctgtcgc tcgccctgga cctggccggg ccgggtgccc ccgccgaggc
     4621 ggtcgccgcc accgcggccg gactggggcc ggtcgggctg ctggtgtgca gcgcgggcgc
     4681 catccggctg gccgccgtcc acgagaccga ggagcggcac tgggaacggc agttgcgggt
     4741 gaacctcacg gtgccgttcc tgctggcccg tgaggtgctg cccggcatgc gggagcgcgg
     4801 cttcggctgg gtcgtgaaca tcggctccgg tgtgggctcg gaggtggtgc cgggcagcgg
     4861 cggctacggc gtcagcaagc acaccgtgca ccggctcacc gagctgatcc acgaggagaa
     4921 ccgcgacctc gggatccgcg cggtcaccgt cgccccgggc tgggtctcca cccggctcgc
     4981 ggcccggccc gccgatctcg gggtgcccga ggaggaggtg ctggacgcgg aggacatcgc
     5041 ggacaccgtc gcgtggctgc tggaccgtcc ggcccggatg agcgtcggcc cgctggtccg
     5101 cgtcgagccc tcggcgagcc gggccgccgc cggtgacgcc atgacccgcc atctgacccg
     5161 ttcccgcgcc gagggcgccg gaccggatgc tgaggagacc cgctgatggg caggaccacc
     5221 ctcatcgagc acgacgtgcc ggtggagatg cgcgacggga cggtgctgcg ggccgatgtg
     5281 tggcgccccg ccgaaggacc ggcctcgccc gccgtgctct tccgcacccc gtacggcaag
     5341 tccccgctgg gtcttgccac cctgaccccg gcccagtgcg tggaccgggg gtacgcggcg
     5401 gtcgtgcagg acacccgggg ccggttcggc tcggagggcg agtgggcgcc gctggactgg
     5461 tcccaggagg ggcccgacgg gtacgacacc gtcgagtgga ccgccgaaca gccttggtgc
     5521 gacgggaacg tggccatggc gggcacctcg taccaggcga tcgtccagtg gctggccgcc
     5581 atggagaagc cgccgcacct gcgggccatc gcgcccacga tgtccacctc ggcccccttc
     5641 gacgccgagc agctcggcgg tttcctgcgg ctggaccacc tcacgagctg gctcggcctg
     5701 accgcgctgg agtgggtgca gcgccgggcg gcggcgggcg atccggtgga cggggcggtc
     5761 gtcgccgagg tcgtgcagct gctcaccgca cccgaagtgc cgctgcgccg ctggccgttg
     5821 tcgaccatcc tcgacttcga ggggtttccc ggccggctgc gggacatctt cgcggggcac
     5881 gtggcgacgg tggccgacta ccacctcggg gaagtcgggg tgcccacctt ctcggtcggc
     5941 ggctggtacg acgtgttctc ccacggcacg atcgagctgc accgcgccgt gcgcgccctg
     6001 gacccggtgg cgggacggca cgagctggtc gtcggaccct gggtgcactc gggtcaactg
     6061 ccgcaggtgc agggcgaggt gaacacgggg ccctacggtt cggcgcaggg cgcacggctg
     6121 gccgatctgc acctggactt cttcgaccgc catctacggc cggccggggg gacgacgggc
     6181 cgggactccg gcggggacgt gcggtatttc ctcttcggcg atgacgcctg gcaccgggcc
     6241 gcgagctggc cgccgcccga ggccgtcgac gcgccctggt acctggcggg tccggccgac
     6301 ggcgaggagg gcggcaggct gctgcccgcc ccgccccggg aggccccggg ccacgacgcg
     6361 ttcacctacg acccggagga cccggtgccc tcgcacggcg ggcgggtgct ccagctcggc
     6421 aggctggcgg cgggcccgct caaccaggcg catctggagg acaggccgga cgtgctctgc
     6481 tacacctccg agccgctcac cgagccgctg gacgccgtcg gccggcagcg gctgcggctc
     6541 cgcttcggct cggacgcacc cgccaccgcc gtggtcgcca aactcaccga cgtacacccg
     6601 gacgggcgtt cgctgctcgt ggccgaggcc agcctccggc tggaggccga gggggacggc
     6661 ccgcgggacg agccgtacga cgccgatctg ctgctcgggg acaccgcgtg gcgcttcgcc
     6721 cccgggcacc ggctgcgggt ccacgtcacc agcagcaact tcccccatct ggaccggcac
     6781 cccaacatcc cgggcccggt cggcgaggcg gagcactgcc gcaccgcccg ccagtcggtc
     6841 tggtacggcg gcccgtacga gagcgtgctg cggctgagca ccctgcccgc gccgagcgcc
     6901 ggggagaccg cgtgatcgac gatgtgctcg atccggcgtc cgccgccgtg cccacggcgg
     6961 agcagtgcgt gctgggtccc ctgctcaggc gacgtgccgc cgcagcaccg gcggcgccgt
     7021 acgcgttgat gccggacggt gacctctgga cgtacgcgcg caccctccgg gagaccgagg
     7081 agacggccgc cgcgctccag gcgctgggag tcgtcccggg cgaactggtg ctgagctggc
     7141 tgcccaacgg acccgacgcg ctgcgcgcct ggtacggggt caacctggcg ggcgcggtcc
     7201 tggtgccgct caacatcgcc taccggggtg cgatcctgcg tcaggtgatc gccgacagcg
     7261 gggccgaggt gctgatctgc cggccgtcgc tggcggcccg gctggaggat tcggacgacg
     7321 cggtgggggc ggtgcgcacg gtggtcctgc tgccggggcc cgaggacgcg gcccaggacg
     7381 tggaggcgct cgccgggcgg ctggccacgc gcttccgggt ggagaccgca ctgcgcgcgg
     7441 accgggcgga gttcgcggag ccggtgcccg ccccccggcc gtgggacccg cagaccgtca
     7501 tctacacctc cgggacgacc ggtccgtcca agggcgtcgt ctcctcctac gcgcacctgt
     7561 acagcagttg caccgccgcg ttccacggca tggccggacc ggaggaccgc tatctgctgc
     7621 aactgccgct gttccacgcg ggcggcacga tcggcgcgta cgggatgctg gtgcacggcg
     7681 gttcggtgac ggtcgtgccc gcgttcacca ccggggagtt ctggccgctg atccggcgga
     7741 cggggacgac cctgtgcacg ctgctcggcg tgatggcgac ctatctgctc aagcagccgc
     7801 cgctgccgca ggacaccgcg cacccgttgc gggcggccta cgtcatcccg ttcaccgagg
     7861 gggcgacgga gttctccaag cggttcgggg tcccggtccg cgcgctgttc aacatgaccg
     7921 aggtgtcgtg tccggtgctc tccgcgccgg accaccaccc gggcgtcccg atgcactgcg
     7981 gggagccccg gccggggatc gccgcgcggg tcgtcgacga ccacgaccgg gaggtggcgg
     8041 acggcgaggc gggcgaactg gtgctgcgcg cggaccgtcc gtggtcgttc ctgagcggct
     8101 acctcggccg gcccgccgag acggccgccg tctggcgcaa cggctggttc cacaccgggg
     8161 acaccttccg ccgggccccg gacggcgggc tggtcttcgt ggaccgcaag aaggacgcca
     8221 tccgcaggcg cggcgagaac atctcctcct tcgaggtgga ggcgcaggcg gtggcccacc
     8281 cgggggtgct ggaggcggcg gcggtggcgg tgcccggcga cgagggcgag gacgaggtgc
     8341 tgctggtggt ggcggaccgc gacccctcgg ccccggtcga cccggcggcg ctgctggagt
     8401 tcctgcggga gcggctggcc cacttcatgc tgccgcgcta catccgggtg ctgcccgagc
     8461 tcccgaagac tcccaccggc aagccgacca agcacacgct gcgcgccgag ggcgtggtgg
     8521 cggggacgtg ggaccgcgag gccgcgggca tccggatacg cagggagaag atcgtatgaa
     8581 ccaggaagca ttccgggcgg gccaggaacc cccggccgag tgggcggggg cggcgaccga
     8641 gtcgttcgcg gacttcgccg accgggtgga cggcaaggag gtcgtaccgc tgcgggcctc
     8701 gcttgcgggc ggggtcgcca ccctgacgct ggaccggccg caccgccgca acagcctcga
     8761 cctgacgctc tcccgccatc tgctgctcgg cctgatgtgc gcgggcgacg acccccgggt
     8821 gcgtacggtc gtgatcaccg ggaacggcgg ggcgttctgc gcgggcgacg acgtcgggag
     8881 cgtacggcgg tggcggctgg gcgaccgggc ggacaccccc ttcgacccga tcacctcgga
     8941 cgcccactac ctgcgggtct gcgaggcgat cctgcatctg ccgaagccgg tggtcgtggg
     9001 gctgaccggg gcggcggcgg gcgccggggc ggagatcgcc tgcgccgccg acttccggct
     9061 ggcggacacc cgtgcctcga tcggcagttg cctggccggg gtcgggcatg tggggaacgt
     9121 ggtcctgatg tcccggctga ccggtccggc gcgggcgacg gagatctacc tcaccgggcg
     9181 gatggtctcc ggggacgagg cggtgcgcct ggggctgttc gaccggctct gcgaaccgga
     9241 ggatttcgac cgcgaactgg ccgatctggc gggccggttc gcggcactgc cgaccgcttc
     9301 ggtggggctg ttcaaggagt tgcgggagcg gagctggggg cagccggccg agtacgggct
     9361 gcggctccag gacacgtacc acctgaagac gcacgcgacg gtggccgacg cccgggaggg
     9421 gatggccgcg ttcacggaga agcggccgcc ccgcttcacc ggcgcctgac cggtgccggg
     9481 cggggtctcc gcccggcacc ggggtctccg tccggtgccg ggccccgtcc ggtgccgcga
     9541 cccgtcgggg ccgcctccct ttgcggctgc gacggagaga gtattctgat tctgatgaac
     9601 gaagcactcc ggcaccgccg cccggcggcc tcgccgcctc cgcctccgcc cctgtccgcg
     9661 cccctgtccg cgttcaccgc cggccccgcc gaggaggccc cccgatgacc ggccccgacg
     9721 gccgaaccgt caccggggcc cgcgtcgagg agacggcgca cagcatcgac gtctccggcg
     9781 cccggctgca ctactggacc gccggagctg cggaccgccc ggggatcgcg ctgacccacg
     9841 gcgccggggc cgaccaccgc atgttcgatc cgcagatccc ggcactggtc ggcgcgggct
     9901 accgcaccct gcgctgggac gtgcgctacc acggggcgtc cgtctccggc acgggcagat
     9961 tccgtacggt ctacgcggcg cgggacctgg cagcgctgct ggacgcggcc gggatgcccc
    10021 ggcccgtggt gctgctgggc cagtcgatgg gcggcaacat cgcgcaggag tatctgcgcc
    10081 gacggcccga cgaggtcgcc gcactcgtgg tgatcggctc cacctccaac accctgccca
    10141 tcacccgggc cgagcggcgc ggcctggcgt tctcccgcgc cttcatgcgg ctgatgccct
    10201 accgtcggct gacccggtcg atggccaggg cgtcggccga ggaccccggt gcgcggacgt
    10261 atctgcgcga gaccttcctg gccaacggga ggcgctcctt cctcaccacc tgggacggca
    10321 tgacccgcgc gatcgacccg tcccccgact accgggtcga gaagcccgaa cttctcctct
    10381 gcggtgaaca cgacagcacg ggtaacatcc gctcggcgat ggaacggtgg agcgaacgcg
    10441 atccccacag cgagttccat gtgatccccg gtgccggaca tgtcgccaat ctggaccgtc
    10501 ccgacgaggt caaccggctg accgtcgcct tcctgaaggc ctgagacccc agcgagacca
    10561 tgactgacca cgacatcacg cccgacgcgg gacccctccc gatgcccggc tccgacgggt
    10621 tcagcgacgc ggaagccgcc ttcatcagcg agatgggttc gctgatggag cgctggggcc
    10681 tcccgcaggc caccggccgc ctcttcggct acctcctgct gcgcaacaag ccggtggacc
    10741 tcgacaccat gacccgcgaa ctcggccagg ccaagagcgg gctgagtgtg gccgcccgcc
    10801 aactggaggc ctggtccctg gtgcggcgct cgaccagggc cggcagcagg cggatcgact
    10861 acgaggcggt gggcgacctc cagcacctgc tgctggtgaa caacgcccat atgcgcaagt
    10921 tcaccgagac gctgagctcg ggaatcccgg tggcgcgcgg cgaggcccgg gaccgactgg
    10981 cctcgctcgc cggcctgttc aacgggtacg tggagcagac cgaggcgctg gtggccgcct
    11041 gggaggcccg gcgcgccgcc acctgagccc ggccgttccc ttctcccttc tgagcccggc
    11101 cgttctcttc tccctccttc tccgcttcct cgtccttccc cttcctgctt ccgatggagt
    11161 gaccgtgaac gtgtcgtccg tccccgcgcc gggcaacgga acaacggtgg ccaccgccgt
    11221 ggcggaccct ggagtccgga tccgcccgcc ggtcatggac gcctgctcgc tggtgtacga
    11281 cgacgcgggc tggcgggcgt acctgaaccg gctgggcgag aacgcccctg agtacctgga
    11341 tgtcttctcc gcctcgttct gccggtactt cggcgcctcg cacaccgcgt accgcgacgc
    11401 gctcgccgtc cgccggcagg acgcgatcga cgtgctcctg ccaccggacc ggccaccgtt
    11461 cgatctggcc gggcatctcg cggaccggga acggcagggt gtgacgggcg agttcgccat
    11521 gggctcggcg gaacggctgc cggacggccg tacggtcaac gagtggctgc tggagaccgt
    11581 acgggacgtg cgcgaccgga tccacgtctg ggccgggatc tccctgcgcg accccgccgc
    11641 cgcgctgcgg gagctggagc ggtcgctggc ggccggggcg accgggctgt gcgtcatccc
    11701 cttcctggac ggcaccgacc cggccgaccc gaggttcgcc ccggtctggg acgccgcggc
    11761 cgaggcgcgg ctgccggtct ggctgcacac cggccaccac ttcgcccgga gccaccccag
    11821 cggcctgggc agctggcgta cggtcgagac gctcgcgggc cgccaccgcg cgctgctgct
    11881 cgtcgccggg cacgcgggct ggcccgatgt gcaggagatg ctgctcacgg ccgcccggca
    11941 ccccggggtc ttcctggagt tctcctcgca ccggccccgg cacatgtcca agcccggctc
    12001 gggctgggag cccctgctgc accacgcccg ggggatggcc cgcgaccggg tcatgttcgg
    12061 cacctcgacc tgggtcaatc cggggccgac gggaccgctg gccgatgagc tggccgcgct
    12121 cccgctcccc gccgacgtgg tcgccgcctg gctctcgggc aacgcggagg cgctggtcgc
    12181 ccgtgcggcc gggacccacc ggggctgagc cgcgccggga gccctccgga tgatgcggac
    12241 ccgtcgccgg gggcagggga tccgccggac ggccgaaagc cgcagccccg tcggaagcct
    12301 ctttccggca cacgtgggca ggaggcggat cctggccggg ccgggcctac cgtcggcctg
    12361 gtcagccacc ccgaccaacg gagatgtacg acatggcaaa gatccttttc gtggtgtccg
    12421 gcgcggacca ctggaccctg gcggacggca cggcccaccc cacgggcttc tgggccgagg
    12481 aggccgtggc gccgtaccgg gcgttcaccg acgccgggca cgaggtggtc gtcgccaccc
    12541 cgggcggcgt cgtcccgacc gtggaccggg gcagcctggc gcccgacgtc aacggcgggc
    12601 aggagggcgc cgacgcggtg gcggccggtc ttgaggcgtt cgaggagctg cggcggccgg
    12661 tcgccctgga ggacgtggac ccggacgtgt acgacgccgt cttctacccc ggcggccacg
    12721 gcccgatgga ggacctcgcg gtggaccccg tctccgggcg gctgctcgcc cgggtgctgg
    12781 cttcgggcaa gccgctcggc gtggtctgcc acggcccggc ggcgctgctg gccgcgaccg
    12841 gacccgacgg ccggtccgcg ttcgccgggt atcggctgac gggcttcacc aacgccgagg
    12901 aggcccaggc gggcttcgcg gacaaggcga agtggctgct ccaggaccgg ctggtggcgc
    12961 tgggcgcgga cttccaggaa ggtgagccct gggcgccgtt cgtcatcacc gaccggaacc
    13021 tgatcacggg tcagaacccg gcctcctccg tcccgttggc cgccgaactg ctcaaccggc
    13081 tcggctgacc ggccgatcgg cggttcgccg cccggccggc cgggctgttc agacccagtc
    13141 ccgccgcgcg ggcggctcgc agagctccag caccaccgcg cccgtctcgg gctcgtcccc
    13201 ggagacgggc cggacgcgcg caccgaccgt caccaggtgc ggagccgccc ccacgatctg
    13261 gcagcggaag acgaaccctt ccgagaaccg caccagggac tcgttgcgcg cagcctcggt
    13321 atagcggtgg accacggcgg tccggacgac cacgccgtgg ccggtggtgc gttcgggctc
    13381 cagttcgctc gacgcgcaca ccgggcacag cagccgccgg aacgaggcgg tgccgcacca
    13441 gcggcagcga ttgtaggaga ggccgcactc ctcgtgcgcc ttctggacgg tgcccattgc
    13501 tgtctgggac acggctcgac cccctgcgct cgactcggac gcgccgcacc tgcactgcgg
    13561 gcgcgtccgc accatatggc actcagtgcc ggaccgtaaa ggcactgagt gcccattggt
    13621 actcagttct cgccgacggc tgcctcgatc tgctgcacga cacgccacat cggggtgccc
    13681 ttccgcgcga ccatcacgat cacctcccct ttcccgtcgc cgccaccgga gaccggaaag
    13741 ggggtggccg gtgtggggac ggcaggccgc ccccacacct ctcggaccag ggcgagcgca
    13801 tgatccacag ccgcctcggg gtcgcccgcc ccgcccgaac gcagccacag ccgaagcccg
    13861 ttgttgtgcg cggcgaccac cgaagcggcg atcacctcgg cccgcagctc cccgtcgcga
    13921 ccctcgccga agcgaccccg cagatgtccg gcgagagtct gttcgtaacg gcgcaccacc
    13981 gacagttcgt acgtccgcag ccccggcacc tcccgagtga ggcggtagcg ctgcacggag
    14041 aactcggggt tggccgcgta catccgcagc acgatgcgcg cggcgtcgca caccgcgccg
    14101 accgggtcgc tgtcgtcgac ggcggccagg aactcggtcg tctcggcgag gcagcgctcg
    14161 tggtccggga agaccgcgtc ctccttggac gggaagtagc ggaagaacga acgccggccc
    14221 accccggcca gcgccacgat gtcgtccacg gtcgtccgct cgaagccccg ctccaggaag
    14281 agccggaagg ccgcctgtgc gagcacctcc cgcatgggtg ccttcttctc ggatcctcgc
    14341 gcctcgctca tgcggcgaaa cgtagcaccg cgaggaggat tttggcactg cgtaccttta
    14401 cagagggtac tgagtgccat aatctctcca tcagtacgaa tgacacccag gtgggaccac
    14461 acccaggtag gcaggagagc cggcgtgagc ttgaggatcg ttgtctgtgt gaagtacgtg
    14521 cccgacgcga ccggtgaccg gcgtttcgcc gatgacctga cgctggaccg tgaggatgtc
    14581 gacggtctgt tgtcggagct ggacgagtac gcggtcgagc aggcgttgca gatcgctgac
    14641 ggggcggacg atgcggagat caccgtggtg acggtgggtc cggaggatgc caaggacgcg
    14701 ttgcgcaagg cgttgtcgat gggtgcggac aaggcggttc acgtcgagga cgacgatctg
    14761 cacggcagtg atgtgatggg gacgtcgctg gtgctggcga aggctgtgga gaaggccggg
    14821 tatgacctgg tgatctgtgg gatggcgtcg acggacggtg tgatgggtgt gctgccggcg
    14881 ttgctggcgg agcgtctggg tgtgccgcag gtgacgttgc tgtccgaggt cgcggtggac
    14941 ggtggtgtgg tgacggggcg gcgtgacggt gacacggcgt ccgagcagct tgaggcgtcg
    15001 cttcccgcgg tggtgtcggt gaccgaccag tcgggtgagg cccgttaccc gtcgttcaag
    15061 gggatcatgg cggcgaagaa gaagccggtg gagtcgctgg acctggacga tctgggtctg
    15121 gacgcggacg aggtcggtct ggcgggtgcg tggacggtgg tggattccgc caccgagcgt
    15181 ccggcgcgga cggcgggcac gatcgtgaag gacgagggtg agggcggcag gcagctcgcc
    15241 gggttcctcg cgggccagaa gttcatctag tccgcatgtc tttccccgct gttcctctct
    15301 ctcgtccttt cttgtctgga gtgcgttgtc atggctgaag ttcttgttct ggtcgatcac
    15361 gtggacggtg cggtccgcaa gcccaccctg gagctgctga cgctggcgcg tcgtgtcggt
    15421 gacccggtcg ccgtggtgct gggtgccggt gccggggacg ctgccccggt gctgggtgag
    15481 cacggtgcgg tgaaggtcct gacctcggac gccccggagt tcgcggatta tctggtggtg
    15541 ccgaaggtcg acgcgctgc
//
