BGC0000253: oviedomycin biosynthetic gene cluster from Streptomyces antibioticus
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Location: 1 - 24,720 nt. (total: 24,720 nt).
This entry is originally from NCBI GenBank AJ632203.2.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
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resistance
TTA codons
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Gene details
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General
Compounds
Genes
Polyketide
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000253
Short description oviedomycin biosynthetic gene cluster from Streptomyces antibioticus
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide (Angucycline)
Loci NCBI GenBank: AJ632203.2
Compounds
  • oviedomycin
Species Streptomyces antibioticus [taxonomy]
References
Chemical products information
oviedomycin
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C19H10O7
Chemical database entries
NPAtlas
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • CAG14955.2
 2 - 1219 (+) tRNA-synthetase class I
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  • CAG14956.1
 1226 - 1861 (-) putative pyridoxine 5-phosphate oxidase
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  • CAG14957.1
 1862 - 2224 (-) ArsR regulator
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  • CAG14958.1
  • ovmE
 2389 - 3627 (+) putative transmembrane efflux protein from the major facilitator superfamily
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  • CAG14959.1
  • ovmX
 3855 - 4688 (+) putative nucleotide-diphosphate-sugar epimerase
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  • CAG14960.1
  • ovmY
 4685 - 5332 (+) TetR-family transcriptional repressor
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  • CAG14961.1
  • ovmZ
 5534 - 6259 (-) ovmZ protein
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  • CAG14962.1
  • ovmR
 6760 - 7527 (+) IclR-family regulator
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  • CAG14963.1
  • ovmOI
 7963 - 9447 (+) oxygenase
  • Tailoring (Hydroxylation)
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Sequence-based prediction
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  • CAG14964.1
  • ovmC
 9556 - 9888 (+) cyclase
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  • CAG14965.1
  • ovmP
 9885 - 11009 (+) keto-acyl synthase alpha
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  • CAG14966.1
  • ovmK
 11006 - 12229 (+) keto-acyl synthase beta
  • Scaffold biosynthesis
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Sequence-based prediction
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  • CAG14967.1
  • ovmS
 12310 - 12582 (+) acyl carrier protein
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  • CAG14968.1
  • ovmT
 12706 - 13488 (+) ketoreductase
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  • CAG14969.1
  • ovmA
 13516 - 14463 (+) aromatase
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  • CAG14970.1
  • ovmOII
 14453 - 15925 (+) oxygenase
  • Tailoring (Hydroxylation)
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Sequence-based prediction
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  • CAG14971.1
  • ovmOIII
 15945 - 17465 (+) oxygenase
  • Tailoring (Hydroxylation)
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Sequence-based prediction
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  • CAG14972.1
  • ovmF
 17521 - 18402 (+) 4'-phosphopantetheinyl transferase
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  • CAG14973.1
  • ovmG
 18386 - 19930 (+) acetyl-CoA carboxylase complex, beta-chain
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  • CAG14974.1
  • ovmH
 20498 - 22216 (+) acetyl-CoA carboxylase complex, alpha-chain
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  • CAG14975.1
 22247 - 22765 (-) putative MarR-family repressor
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  • CAG14976.1
 22849 - 23652 (+) putative 3-keto-acyl carrier protein reductase
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  • CAG14977.1
 23903 - 24418 (+) hypothetical protein
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  • CAG14978.1
 24415 - >24720 (+) hypothetical protein
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Polyketide-specific information
Subclass Angucycline
Starter unit Malonyl-CoA
Ketide length 10
Cyclic? yes
Polyketide-synthases
Genes Properties Modules
ovmP
+
ovmC
+
ovmS
+
ovmA 		Synthase subclass: Type II
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: QGSJT55NWIBPAZQIATLZ7G55, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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