BGC0000256 - 1 region(s) - antiSMASH results

BGC0000256 (Actinomadura hibisca)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T2PKS	1	37,100	pradimicin-A	PKS	100%

BGC0000256 - Region 1 - T2PKS

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Location: 1 - 37,100 nt. (total: 37,100 nt) Show pHMM detection rules used

Region on contig edge.

T2PKS: (t2ks and t2clf)

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Detailed domain annotation

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000256	1.00	Polyketide	pradimicin-A	Actinomadura hibisca
BGC0000231	0.39	Polyketide	griseusin A, griseusin B	Streptomyces griseus
BGC0000025	0.34	Polyketide	avermectin	Streptomyces avermitilis
BGC0002031	0.32	Alkaloid	kitasetaline	Kitasatospora setae KM-6054
BGC0001605	0.29	Terpene	gibberellin	Sinorhizobium fredii NGR234
BGC0001928	0.29	Other	(2R,3S,4S)-5-fluoro-2,3,4-trihydroxypentanoic acid	Streptomyces sp. MA37
BGC0002218	0.29	Terpene	(-)-Cyatha-3,12-diene	Dentipellis sp. KUC8613
BGC0000019	0.28	Polyketide	angolamycin	Streptomyces eurythermus
BGC0000272	0.28	Polyketide	spore pigment	Streptomyces collinus
BGC0001197	0.28	Polyketide	frankiamicin	Frankia sp. EAN1pec

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000256	1.00	Polyketide	pradimicin-A	Actinomadura hibisca
BGC0000231	0.71	Polyketide	griseusin A, griseusin B	Streptomyces griseus
BGC0000025	0.67	Polyketide	avermectin	Streptomyces avermitilis
BGC0002031	0.65	Alkaloid	kitasetaline	Kitasatospora setae KM-6054
BGC0001605	0.63	Terpene	gibberellin	Sinorhizobium fredii NGR234
BGC0001928	0.62	Other	(2R,3S,4S)-5-fluoro-2,3,4-trihydroxypentanoic acid	Streptomyces sp. MA37
BGC0002218	0.62	Terpene	(-)-Cyatha-3,12-diene	Dentipellis sp. KUC8613
BGC0000019	0.62	Polyketide	angolamycin	Streptomyces eurythermus
BGC0000272	0.62	Polyketide	spore pigment	Streptomyces collinus
BGC0001197	0.61	Polyketide	frankiamicin	Frankia sp. EAN1pec

Similar known gene clusters from MIBiG 4.0

Type II PKS

Type II PKS gene cluster prediction details

Cluster section:: 0 to 37100
Starter unit(s):: malonamyl-CoA (Score: 625.0; E-value: 0)
Malonyl elongations:: 11|12 (Score: 679.7; E-value: 2.6e-207)
Product class(es):: pentangular polyphenol
Product molecular weight(s):: malonamyl-CoA_11: 876 Da
malonamyl-CoA_12: 918 Da

pdmA: KS (Score: 775.5; E-value: 2.7e-236)
pdmB: CLF 11|12 (Score: 679.7; E-value: 2.6e-207)
pdmC: ACP (Score: 102.7; E-value: 2e-32)
pdmD: CYC C9-C14 (Score: 246.2; E-value: 2.3e-76)
pdmF: MET C11O (Score: 527.4; E-value: 3e-161)
pdmG: KR C19 (Score: 387.1; E-value: 7.8e-119)
pdmK: CYC C4-C21/C2-C23|C2-C19 (Score: 136.6; E-value: 6.8e-43)
pdmL: CYC C5-C18 (Score: 219.9; E-value: 2e-68)
pdmN: AMID (Score: 844.6; E-value: 8.7e-257); AMID ADE34521.1_SF2575_malonamyl-CoA (Score: 625.0; E-value: 0.0)
pdmQ: GT (Score: 239.5; E-value: 1.9e-73)
pdmS: GT (Score: 299.2; E-value: 1.4e-91)
pdmT: MET C13O|C17O (Score: 503.5; E-value: 5.2e-154)