LOCUS       BGC0000256             37100 bp    DNA     linear   BCT 03-JAN-2007
DEFINITION  Actinomadura hibisca strain P157-2 pradimicin biosynthetic gene
            cluster, complete sequence.
ACCESSION   BGC0000256
VERSION     BGC0000256
KEYWORDS    .
SOURCE      Actinomadura hibisca
  ORGANISM  Actinomadura hibisca
            Bacteria; Actinobacteria; Streptosporangiales; Thermomonosporaceae;
            Actinomadura.
COMMENT     On or before Jan 3, 2007 this sequence version replaced EF066366.1,
            EF066367.1, EF066368.1, EF066369.1, EF066370.1.
            ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2022-11-07 17:56:47
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 37100
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..37100
                     /db_xref="taxon:68565"
                     /mol_type="genomic DNA"
                     /organism="Actinomadura hibisca"
                     /strain="P157-2"
                     /type_material="type strain of Actinomadura hibisca"
     subregion       1..37100
                     /aStool="mibig"
                     /contig_edge="True"
                     /label="Polyketide"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..37100
                     /contig_edge="True"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(368..1714)
                     /gene="pdmP1"
     CDS             complement(368..1714)
                     /codon_start=1
                     /gene="pdmP1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090:acetyl-CoA carboxylase biotin carboxylase (Score:
                     655; E-value: 2.4e-198)"
                     /gene_kind="biosynthetic-additional"
                     /product="PdmP1"
                     /protein_id="ABM21735.1"
                     /sec_met_domain="ATP-grasp (E-value: 7.6e-09, bitscore:
                     26.2, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 2.2e-08,
                     bitscore: 24.7, seeds: 12, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp_3 (E-value: 4.3e-10, bitscore:
                     30.7, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFSSVLIANRGEIALRVARTCRELGIRVIMVYSTADRDSPALRLA
                     DERVHIGPPAAARSYRYAPAILEAARQTGAEAVHPGYGFLSEDPDFARACESEGLTFIG
                     PPASVLAQLGDKSLAREAAVEAGLPVLPGRVRPLEDGKSARRAAEEAGYPVIIKAVAGG
                     GGRGMTIVRDPDDLLRAYAETRATAFALFGDGRVYLERYLEGARHVEVQVLADGHGTVL
                     ALGARDCSVQRRRQKLVEESPAPGLPDGLVEQMCEAAVQGARAAGYVGAGTYEFLVGDD
                     GFYFMEVNSRIQVEHPVTEMVTGVDLVREQLVAASGGRLSVGPDDVRPRGAAIECRINV
                     EDPDRGFLPTPGLIEVFDAPGGPFTRIDTHAAPGLRVPADYDPLLAKVVVWDRDRDAAI
                     ARMDRALAELRVTGPGVHTTTGFLREVLAHPLFRAAKHTTGLVDTMVVD"
     misc_feature    368..29023
                     /note="pradimicin biosynthetic gene cluster"
     gene            complement(1737..2198)
                     /gene="pdmP2"
     CDS             complement(1737..2198)
                     /codon_start=1
                     /gene="pdmP2"
                     /product="PdmP2"
                     /protein_id="ABM21736.1"
                     /transl_table=11
                     /translation="MLAGASRVPPRSVRLRAGELSVEVDWPEPAAATGAVVETAAGTAV
                     AAVAAALPAPVEAAPTEDGPGRPLLAPLVGVFYRAPEPGAEPFAREGDLVQAGQQVGIV
                     EAMKLMNPIEADRTGRVVRVLVADGDPVEYGQPLLLIDDDLGGTGEEAA"
     gene            complement(2357..4018)
                     /gene="pdmP3"
     CDS             complement(2357..4018)
                     /codon_start=1
                     /gene="pdmP3"
                     /product="PdmP3"
                     /protein_id="ABM21737.1"
                     /transl_table=11
                     /translation="MGALPRLRGDPVRAALRAHAQGVRGVRAARPDERGRARRAAVRPR
                     RAGAAVAADHRRPARLHRPGAVRAAAPRRRREDRARRGRGVRARHHRGLPAGRGRHGLR
                     VHGRQPRQRGGRADRRRRRGVVAGAGAVAAGHRVGRRADAGGRAVAHADGEDQPGARDA
                     RRGGHRDHRADHRPDLRRGGGLVRDAAGRAARRAGRAHRVRRAPRHRADDRATAAGGVP
                     DRRVPARQGPAGRGGAARRAAQHARPDARAAAHRAARGARPGGARRGRPRPRAAAGPGG
                     HRGGAAGPAHRAAERPRLRRHDAGGVPRAARRPAGRRLPGDPRRHRAARRAARHADRAR
                     QGARHRRPGAPQLRDAVARRVPQGGPADAAGGQARRARRHADRHSGRASRRRSRGERAG
                     VGDRGEPAADVAAARPDRGGGDGRGRQRRRARAGRRRPGADPGQRRLLGDQPGGLRGDP
                     VEGPGPRVGGARRRRTAARRPGTARARRGGRGGPRARRGRAHRPARHRRPRARGRRRGA
                     GRTGRTGPCRTGRRTARPFPPLRSRRPGGSRGDREA"
     gene            complement(4053..5045)
                     /gene="pdmY"
     CDS             complement(4053..5045)
                     /NRPS_PKS="Domain: NAD_binding_4 (4-178). E-value: 4.5e-16.
                     Score: 50.5. Matches aSDomain:
                     nrpspksdomains_pdmY_NAD_binding_4.1"
                     /codon_start=1
                     /gene="pdmY"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score:
                     329.2; E-value: 4.7e-100)"
                     /gene_kind="biosynthetic-additional"
                     /product="PdmY"
                     /protein_id="ABM21738.1"
                     /sec_met_domain="NAD_binding_4 (E-value: 2.3e-16, bitscore:
                     50.5, seeds: 102, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 1.4e-20,
                     bitscore: 64.4, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="RmlD_sub_bind (E-value: 7.9e-19, bitscore:
                     58.6, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRILVTGGAGFIGSHYVRSVLAGRYPAVADALVTVVDKLTYAGNT
                     DNLPIGDPRLTFVKGDICDVPLLRELLPGHDAVVHFAAESHVDRSLVSAGEFAVTNVLG
                     TQSLLDCCVLAGIGRVVHVSTDEVHGSIDTGSWDEAAPVDPRSPYAASKAASDHFALAY
                     HHTHRLPVMITRCSNNYGPYQFPEKVIPLFVTNLLAGRPVPLFGDGLHRRQWLHVSDHC
                     DAVQRVLEDGAPGEVYNIGGGAELTNRELTERLVALCGGGPDSVRHVADRKGHDRRYAL
                     DDTKIRTSLGYRPRVDFETGLAEVVRWYRDNVEWWEPRRAELRAFPRGW"
     aSDomain        complement(4512..5033)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_pdmY_NAD_binding_4.1"
                     /evalue="4.50E-16"
                     /label="pdmY_NAD_binding_4.1"
                     /locus_tag="pdmY"
                     /protein_end="178"
                     /protein_start="4"
                     /score="50.5"
                     /tool="antismash"
                     /translation="VTGGAGFIGSHYVRSVLAGRYPAVADALVTVVDKLTYAGNTDNLP
                     IGDPRLTFVKGDICDVPLLRELLPGHDAVVHFAAESHVDRSLVSAGEFAVTNVLGTQSL
                     LDCCVLAGIGRVVHVSTDEVHGSIDTGSWDEAAPVDPRSPYAASKAASDHFALAYHHTH
                     RLPVMITRCSN"
     gene            complement(5042..6109)
                     /gene="pdmX"
     CDS             complement(5042..6109)
                     /codon_start=1
                     /gene="pdmX"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 327.1; E-value:
                     1.6e-99)"
                     /gene_kind="biosynthetic-additional"
                     /product="PdmX"
                     /protein_id="ABM21739.1"
                     /transl_table=11
                     /translation="MKALVLAGGSGTRLRPFTHTLAKPLVPVANKPVLFHCLESIRDTG
                     VREVGIIVSPQGEEIRRAVGDGSRFGLRVTWIPQDAPLGLAHCVLIAADFLAGDDFVMY
                     LGDNIVVGGIGHLVKQFAAERPAALLMVGPVADPREYGVAEVGAGGRVHGLAEKPQLPV
                     SDLALIGVYVFSAAIHSAVRAIRPSARGELEITDAVELLIRRGEDVRAHVFAGYWKDTG
                     RVDDLLECNRELLASIPPARLGSVDEASELIGAVFVDDGARVVRSRVEGPAVIGPASTV
                     TDSRIGPGTSIGAGCVLARAGIAGSIVLDGASVSDVRDLHRSVIGRNARVRALPPQDGA
                     RRLLLGDSSEVVIER"
     gene            complement(6106..7311)
                     /gene="pdmW"
     CDS             complement(6106..7311)
                     /codon_start=1
                     /gene="pdmW"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007:cytochrome P450 (Score: 416.8; E-value:
                     1.4e-126)"
                     /gene_kind="biosynthetic-additional"
                     /product="PdmW"
                     /protein_id="ABM21740.1"
                     /sec_met_domain="p450 (E-value: 2.3e-22, bitscore: 70.2,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="METTPLPYPFRRPSALEPPAELRGLREQPVVKVVLPSGDEAWMVT
                     RYADVRALLADDRISRNLNRPGAARISAKNKLFQDPKMDPDPPEHTRIRRLVMKALTPS
                     RVERLRPRVQEITDRLVTAMAERRPPIDVNEALAYPLPIQVVCELLGVPVEDQERFRVW
                     TGAFLSISGYTQDEIERNMSRLNEYMRDLIEAKRADPADDLISAMIAVTDAEDGRLSEY
                     ELHWWSRLLVLVGFETTAVQIGGCIAMLLSRPDQLDLVRKDPALLRPAVEELLRWKIVG
                     SSVTMLRYVTEDVEVGGVTIPAGSSIIPAGDSANQDESVFEHPEVFDVTRTDNPHLTFS
                     HGTHYCAGASLARLELEVVLSTLIRRLPDLRLAIPATDLRRNDGNLLESFREIPITWGG
                     RG"
     gene            7493..8488
                     /gene="pdmV"
     CDS             7493..8488
                     /codon_start=1
                     /gene="pdmV"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083:oxidoreductase (Score: 231.8; E-value: 1.9e-70)"
                     /gene_kind="biosynthetic-additional"
                     /product="PdmV"
                     /protein_id="ABM21741.1"
                     /transl_table=11
                     /translation="MRLGVNVTHRDPWIAREAERLGYELALVPEGFRADAVSTLGHLAA
                     STERIALSCIAQIPARTPSMAAMTAAALDALSGGRFRLGLGVSNAYATEIWHGLPFARP
                     LARTREYVEIVRAALSGAEVRYEGEHFTVPLPGRDGAPLRLDPVAVPLYLAAVGPRNLE
                     LAAELADGWIAVFRTAEQIADSLPHLAAGQARDGFEVLLTAQLAVGDDDLDELAAPLRA
                     HPARFMSLGHREQNFYYRQAAAMGYEREAALVQDRNAAGDAAGAAEAVPFGFVDATSLI
                     GPVARIADRMKSYAAAGVTTLVITPYAADEAGRVAALRAAAEALDHAGVG"
     gene            8581..9711
                     /gene="pdmU"
     CDS             8581..9711
                     /NRPS_PKS="Domain: Aminotran_1_2 (34-160). E-value:
                     2.8e-14. Score: 44.8. Matches aSDomain:
                     nrpspksdomains_pdmU_Aminotran_1_2.1"
                     /codon_start=1
                     /gene="pdmU"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056:DegT/DnrJ/EryC1/StrS aminotransferase (Score:
                     345.8; E-value: 5e-105)"
                     /gene_kind="biosynthetic-additional"
                     /product="PdmU"
                     /protein_id="ABM21742.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 4.1e-99,
                     bitscore: 323.0, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPFNRPFTTGREAAYMTEALSSGSTGGDGPFTRRAAEHLARLLGS
                     PRVLLTTSCTHALELAALLLDLAPGDEVVMPSFTFTSTANAFALRGAVPVFVDVRPDTL
                     NIDERLVEAAITERTRAIVVVHYAGVACEMDAISKIADRHGIPVVEDNAHGLGGFYRGR
                     PLGSLGALATQSFHVTKNVQCGEGGALVVNDERFAERAEILREKGTDRSRFFRGEVDKY
                     RWQDLGSSYLPSDVLAAFLLAQLEAFADIQARRAHIWAAYHERLAMWASANGVARPELP
                     PGCVHPAHLYYLLLPTPEGATALIDDLARRGVQATRHYQPLHNAPAGLRSGRTGPGGCP
                     VTERVADSLVRLPLFAGMDGRELAHIVDSVNRHPAR"
     aSDomain        8683..9060
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_pdmU_Aminotran_1_2.1"
                     /evalue="2.80E-14"
                     /label="pdmU_Aminotran_1_2.1"
                     /locus_tag="pdmU"
                     /protein_end="160"
                     /protein_start="34"
                     /score="44.8"
                     /tool="antismash"
                     /translation="AAEHLARLLGSPRVLLTTSCTHALELAALLLDLAPGDEVVMPSFT
                     FTSTANAFALRGAVPVFVDVRPDTLNIDERLVEAAITERTRAIVVVHYAGVACEMDAIS
                     KIADRHGIPVVEDNAHGLGGFY"
     gene            complement(9759..10778)
                     /gene="pdmT"
     CDS             complement(9759..10778)
                     /codon_start=1
                     /gene="pdmT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:O-methyltransferase (Score: 285.9; E-value:
                     7.5e-87)"
                     /gene_kind="biosynthetic-additional"
                     /note="O-methyltransferase"
                     /product="PdmT"
                     /protein_id="ABK58689.1"
                     /transl_table=11
                     /translation="MTVTGTPENAHDVLRMGIAYFRSKVLLSAVELGLFTRLAKGPATG
                     PQLRGELGLHPRAARDFLDALVSLGLLRRENGVYDNTAVADTYLDAAKPTYTGGFLTML
                     DHQFAQWGDLTRLLREGGRAYPVDDELDQHDEMHADPARLRRFMSAMDGINQFSGAALA
                     DAYDWSAHASFVDLGGARGNLAAELRKAHPHLAAGVMDLPAVQTVFDEHMESLGLTGQV
                     AFTGGDFFNDPLPAAEVLIFGHVLHDWSPELRAALVRRAYEALPSGGELLVYDVMIDDE
                     RRTHDFSLLTSLHMMLVSPGGGEYTARDCREWMTAAGFGVTRTVPLTDIDTLVIARKR"
     gene            10973..12286
                     /gene="pdmS"
     CDS             10973..12286
                     /codon_start=1
                     /gene="pdmS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MGT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1062:glycosyltransferase, MGT family (Score: 277;
                     E-value: 5.1e-84)"
                     /gene_kind="biosynthetic-additional"
                     /note="putative glycosyltransferase"
                     /product="PdmS"
                     /protein_id="ABK58688.1"
                     /sec_met_domain="MGT (E-value: 2.9e-52, bitscore: 169.0,
                     seeds: 193, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANILISTMPESGHVNPALPIAAALTARGHRVRWHTGAEYTDTIE
                     ATGARLVPMRHAPRFRELPPRRDPSSGWDAVSAVLERLYVAPSLGQLRDFQEILADFPA
                     DVVFNESTAGLGGHLLHDLGGPPWARLGVSMPPTLPDSPIPPLYSPRLFTDTPELLDYS
                     ADPAAIARYRELNHEVAHVHLRPFTDALNALRAEVGLAPMPPGRTALDATISPFLHVQT
                     GTPTFDYPRDELPPQIRHVGPLLPPPSGAAFDPPPWWPEVTSGDQPVVHVTQGTVATDL
                     AQLLAPTLAGLAGEDVLVVATTPDPAALGPLPDNVRVAPSIPYAHLLPLVDVMITNGGI
                     GGVLAALAQGVPLVATGRTEDKPAICARIAYTGVGVDLRSAAPEPDAVRAAVKTVLSDP
                     SYRRNAERIGADFARHDPPAEAADLLERLARTRRPVIA"
     gene            12298..13014
                     /gene="pdmO"
     CDS             12298..13014
                     /codon_start=1
                     /gene="pdmO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1248:methyltransferase (Score: 212.6; E-value:
                     1.1e-64)"
                     /gene_kind="biosynthetic-additional"
                     /product="PdmO"
                     /protein_id="ABM21743.1"
                     /transl_table=11
                     /translation="MFDHQLAEVYDLVYRRRGKDYRAEAAELAAAIRARRPGAASLLDV
                     ACGTGEHLAHLAEHFTEAEGLELSRGMLGVARAKLPHLTLHAADMCTFDLGRRFDAITC
                     MFSSIGYLAERDRMHAAVARMAAHLTPGGVLVIEPWWSPERFIDKYVSGEAVSDAGVTV
                     TRVSRTRRLDDAHAEMEVHFVVADSARIEHFSETHVLGLFSRAEHMAAFADAGCDAEFV
                     EEGPSGPGLYVGVRTG"
     gene            complement(14468..15775)
                     /gene="pdmQ"
     CDS             complement(14468..15775)
                     /codon_start=1
                     /gene="pdmQ"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MGT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1102:glycosyltransferase (Score: 477.8; E-value:
                     5.4e-145)"
                     /gene_kind="biosynthetic-additional"
                     /note="putative glycosyltransferase"
                     /product="PdmQ"
                     /protein_id="ABK58687.1"
                     /sec_met_domain="MGT (E-value: 3.2e-36, bitscore: 116.2,
                     seeds: 193, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADMRIVIATNGSRGDTEPYAALGQGLRRRGHEVRLVASKSYEAL
                     AGVAGIDFFPLDVDMPERLGGGEGQRWLSDGGGTRASVRGFRKFVTPMAEQFMTATAHA
                     CADADAIVFSHLGANAYHVAEARGVPACTAEYLPRHPTGAYPSHLVPGGRSLGRLGNRL
                     SHTAAQQTMWRTRRPAVNEWRTTELGLAPLPWFAGQARSFARDRMPRLCGYSSTVVPRP
                     PDWPRYAQITGYWFLDAPGREPAPELARFVGEGPPPVYVGFGSMVPPDPEATAATIREA
                     LARAGVRGVLLADPERIESTPELLVVREAPHDWLFPRTAAVVHHGGAGTTAAALRAGVP
                     NVVVPFFVDQPFWGSRVAALGAGPDPVPFPELSVPRLADAVARAVGDGGMAERAAGVGE
                     RIRAEDGVAVACEYLERWLGGGPPVPGRRRRFTFGV"
     gene            15826..16869
                     /gene="pdmR1"
     CDS             15826..16869
                     /codon_start=1
                     /gene="pdmR1"
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 203.3; E-value:
                     7.5e-62)"
                     /gene_kind="transport"
                     /product="PdmR1"
                     /protein_id="ABM21744.1"
                     /transl_table=11
                     /translation="MTFACGDTFGEETPMAHAVTAPPGTGGGERAAALAVRGLAKTYPG
                     GRRALAGVDFEVAAGEVFALLGPNGAGKSTTMRILTTLSRPDAGTATIGGVDVVREPQK
                     ARRLIGYVAQRSGVDASGTGRENLTLQGRLHGLSGRTLAARVDALLETVGLTEIADRGT
                     REYSGGTRRKLDIAMGLVHEPRVLFLDEPTTGLDPEVRAEIWEHITGLAGAGALTILLT
                     THYLEEADRLAGRVAILDRGTIVAQGTPAELKGDLRGDAIHVEVLDPAAAEPARRVLAG
                     LARVREVTVDGVTVRALVEDAAGAVPLVLAALTERGVTASSVAVARPSLDDVYLHYAGR
                     SAKEERA"
     gene            16866..17645
                     /gene="pdmR2"
     CDS             16866..17645
                     /codon_start=1
                     /gene="pdmR2"
                     /gene_functions="transport (smcogs) SMCOG1065:ABC-2 type
                     transporter (Score: 177.1; E-value: 5.9e-54)"
                     /gene_kind="transport"
                     /product="PdmR2"
                     /protein_id="ABM21745.1"
                     /transl_table=11
                     /translation="MSTIASQSWFMTARLLRGTVREPLFLIIGLVQPAIWLLIFGQLFY
                     RVTDLQGFGDGRPYLDYLTPGVVVMMALTRGAWSGGNVLEELDHGVLDRFLVSPVSRAA
                     LIAGHLCQQAITIMAQAVLVLGLALAMGARFAGGPVGALVLLLAAILMVLAVGSLSMSF
                     ALVIRRSQSLTAVIQFVLLPLVFLSSAFMDQSLAAGWIRTIARFNPIDWAVLAGRSALA
                     EHPDWQLIGTRLLWLAVLAALCALVAVRSFRSYQRSL"
     gene            complement(17704..19566)
                     /gene="pdmN"
     CDS             complement(17704..19566)
                     /codon_start=1
                     /gene="pdmN"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Asn_synthase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177:asparagine synthase (glutamine-hydrolyzing)
                     (Score: 621; E-value: 3.6e-188)"
                     /gene_kind="biosynthetic-additional"
                     /note="putative amidotransferase"
                     /product="PdmN"
                     /protein_id="ABK58686.1"
                     /sec_met_domain="Asn_synthase (E-value: 5.6e-80, bitscore:
                     260.4, seeds: 78, tool: rule-based-clusters)"
                     /sec_met_domain="GATase_7 (E-value: 1.8e-45, bitscore:
                     144.8, seeds: 307, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGFAGWVDYERDLRREGATTRTMTATMACRGPDAEEVWLSERAA
                     FGHRRLAVLDPKGGRQPMRAEHDGRELAVLAFNGEIYNAGEVRAELAARGHRFRTRSDT
                     EVILEAYLEWGAGCAAKLNGIFAFAVWDPRSEELLLARDQLGAKPVIYYPTPTGVLFAS
                     EPKALLAHPWVDAVVDTDGFRELLSQAGTPGAVVFKGMHEVRAGHVVRIGERGIVTEKY
                     WGLEGREHTDDRDATIANVRRLLEESIGRQLRADVPVCSLLSGGLDSSGLTAIAAHILA
                     ERGEGPVRTFTVDYAGLAENFVPDQVRTSLDAPYVKDLVAHVGSEHTDVMLDTSDLLDP
                     VMRAETIRARDLPSPLGDMQTGLYLLYRAAAEHSTVALTGQLADSLFGGPAWVQDPEFA
                     NADTFPWVALAQRRACPDGLGNGLLAPALRRSLDIPGYVRDRFHEALAEVPHVGEADPQ
                     ERRMREITYTHLTRYPETLIRNDERLSAYVGLETRVPFCDPELLQYAFNTPWHLQTFDG
                     REKSLLRAAVADLLPESVLKRPKSPFPVSVDPGYAKVLRTELSEILADPSAPVAPFLDP
                     QGARELLDDPNSLAEGWRGRTNVELILQLDTWLRDYGVRLDLDV"
     gene            complement(19582..20043)
                     /gene="pdmM"
     CDS             complement(19582..20043)
                     /codon_start=1
                     /gene="pdmM"
                     /product="PdmM"
                     /protein_id="ABM21746.1"
                     /transl_table=11
                     /translation="MSARGVTGAPPRSPAQRKQDALDLLATVRHTWAATGGEKGAHLVP
                     LACVWDGGRVVMSTKAASLTARNLAANGTVRLAFGTAEDVVLLDGEAALVQAADVPDAD
                     RAALAALPLDPGRVPGCVYLFVVPRRVLAWRHLGEMADRVIMSDGRWVV"
     gene            20643..21086
                     /gene="pdmL"
     CDS             20643..21086
                     /codon_start=1
                     /gene="pdmL"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MannoseP_isomer"
                     /gene_kind="biosynthetic-additional"
                     /note="putative cyclase"
                     /product="PdmL"
                     /protein_id="ABK58685.1"
                     /sec_met_domain="MannoseP_isomer (E-value: 7.4e-09,
                     bitscore: 26.5, seeds: 17, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGAPLVSENRPTKITAADVAPNRRRGGDLRVLLGPKTVGTTTGFM
                     GRLSLEPAEFVSEHYHPYSEEFLYVVRGEVLVRVDGEPVVLEPGAALFVPIGVRHRVEN
                     VGVGPAEVVFTLGPLAPRPELGHVDTEELPAPDEQGLDVGGRT"
     gene            21083..22360
                     /gene="pdmA"
     CDS             21083..22360
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (11-396). E-value:
                     1.7e-57. Score: 187.0. Matches aSDomain:
                     nrpspksdomains_pdmA_PKS_KS.1"
                     /codon_start=1
                     /gene="pdmA"
                     /gene_functions="biosynthetic (rule-based-clusters) T2PKS:
                     t2ks"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 482.4; E-value:
                     2e-146)"
                     /gene_kind="biosynthetic"
                     /product="PdmA"
                     /protein_id="ABM21747.1"
                     /sec_met_domain="t2ks (E-value: 3e-243, bitscore: 798.0,
                     seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRPQGGGPRRVAITGMGVVAPGGSGRKAFWNLLTDGRTATRKIS
                     LFDPAGFRSRIAAECDFDPAAEGLTPREVRRMDRAAQLAVVSAREALADSGLVAGEGDP
                     ARFAVSLGSAVGCTMGLEDEYVVVSDQGRDWLVDHSYGVPHLYRHLVPSSLAAEVAWAG
                     GAEGPVTLISTGCTSGLDAVGHGARVIAEGSADVALAGATDAPISPITVACFDAIRATS
                     PNNDDPEHASRPFDRERNGFVLGEGAAVFVLEELEHARRRGAHVYCEVAGYATRGNAYH
                     MTGLKPDGREMAEAIRVAMDAARVAPADLDYINAHGSGTKQNDRHETAAFKRSLGERAY
                     ELPVSSIKSMVGHSLGAIGSIELAACALAIEHGVVPPTANLHNADPECDLDYVPLVARE
                     GRIRTVLSVGSGFGGFQSATVLREAA"
     aSDomain        21116..22270
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_pdmA_PKS_KS.1"
                     /domain_subtype="Iterative-KS"
                     /evalue="1.70E-57"
                     /label="pdmA_PKS_KS.1"
                     /locus_tag="pdmA"
                     /protein_end="396"
                     /protein_start="11"
                     /score="187.0"
                     /tool="antismash"
                     /translation="VAITGMGVVAPGGSGRKAFWNLLTDGRTATRKISLFDPAGFRSRI
                     AAECDFDPAAEGLTPREVRRMDRAAQLAVVSAREALADSGLVAGEGDPARFAVSLGSAV
                     GCTMGLEDEYVVVSDQGRDWLVDHSYGVPHLYRHLVPSSLAAEVAWAGGAEGPVTLIST
                     GCTSGLDAVGHGARVIAEGSADVALAGATDAPISPITVACFDAIRATSPNNDDPEHASR
                     PFDRERNGFVLGEGAAVFVLEELEHARRRGAHVYCEVAGYATRGNAYHMTGLKPDGREM
                     AEAIRVAMDAARVAPADLDYINAHGSGTKQNDRHETAAFKRSLGERAYELPVSSIKSMV
                     GHSLGAIGSIELAACALAIEHGVVPPTANLHNADPECDLDYVPLV"
     gene            22402..23580
                     /gene="pdmB"
     CDS             22402..23580
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (59-388). E-value:
                     6.9e-21. Score: 66.4. Matches aSDomain:
                     nrpspksdomains_pdmB_PKS_KS.1"
                     /codon_start=1
                     /gene="pdmB"
                     /gene_functions="biosynthetic (rule-based-clusters) T2PKS:
                     t2clf"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093:Beta-ketoacyl synthase (Score: 620.1; E-value:
                     2.3e-188)"
                     /gene_kind="biosynthetic"
                     /product="PdmB"
                     /protein_id="ABM21748.1"
                     /sec_met_domain="t2clf (E-value: 1.1e-190, bitscore: 624.4,
                     seeds: 26, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVAPTGIGVEEHWAATLRGVPVIGPLTRFDASRYPSPFGGEVPGF
                     DAAERVPGRLIPQTDHWTHLALAATDLALADAGVVPAELPEYEMAVVTASSSGGVEFGQ
                     REIQALWRDGPRHVGAYQSIAWFYAATTGQISIRHGMRGPCGVVVAEQAGALESFAQAR
                     RYLADGARVVVSGGTDAPFSPYGLTCQLGSGRLSTGADPARAYLPFDAAANGFVPGEGG
                     AILIIEQAATAQDRSYGRIAGYAATFDPPPGSGRPPTLERAVRAALDDARLTPADVDVV
                     FADAAGVPDLDRAEADAIGAVFGPRGVPVTAPKSLTGRLYAGGPALDAATALLAMHDSV
                     IPPTAGGADVPPGYALDLVGAEPRPARLRTALIIARGYGGFNAALVLRGPNT"
     aSDomain        22579..23565
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_pdmB_PKS_KS.1"
                     /domain_subtype="Iterative-KS"
                     /evalue="6.90E-21"
                     /label="pdmB_PKS_KS.1"
                     /locus_tag="pdmB"
                     /protein_end="388"
                     /protein_start="59"
                     /score="66.4"
                     /tool="antismash"
                     /translation="DHWTHLALAATDLALADAGVVPAELPEYEMAVVTASSSGGVEFGQ
                     REIQALWRDGPRHVGAYQSIAWFYAATTGQISIRHGMRGPCGVVVAEQAGALESFAQAR
                     RYLADGARVVVSGGTDAPFSPYGLTCQLGSGRLSTGADPARAYLPFDAAANGFVPGEGG
                     AILIIEQAATAQDRSYGRIAGYAATFDPPPGSGRPPTLERAVRAALDDARLTPADVDVV
                     FADAAGVPDLDRAEADAIGAVFGPRGVPVTAPKSLTGRLYAGGPALDAATALLAMHDSV
                     IPPTAGGADVPPGYALDLVGAEPRPARLRTALIIARGYGGFNAALVLR"
     CDS_motif       23026..23064
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_pdmB_0001"
                     /evalue="3.10E-04"
                     /label="PKSI-KS_m4"
                     /locus_tag="pdmB"
                     /protein_end="221"
                     /protein_start="208"
                     /score="13.8"
                     /tool="antismash"
                     /translation="FDAAANGFVPGEG"
     gene            23605..23868
                     /gene="pdmC"
     CDS             23605..23868
                     /NRPS_PKS="Domain: PP-binding (9-79). E-value: 1.9e-11.
                     Score: 36.2. Matches aSDomain:
                     nrpspksdomains_pdmC_PP-binding.1"
                     /codon_start=1
                     /gene="pdmC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1129:acyl carrier protein (Score: 105.6; E-value:
                     1.7e-32)"
                     /gene_kind="biosynthetic-additional"
                     /product="PdmC"
                     /protein_id="ABM21749.1"
                     /sec_met_domain="PP-binding (E-value: 9.6e-12, bitscore:
                     36.2, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATRERTIDDLRALMRAAVGEADDIDLDGDILDSTFTELEYDSLA
                     VLELAARIETQWGVLIPEDDASGLETPRMFLDYVNGRAVAER"
     aSDomain        23632..23841
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_pdmC_PP-binding.1"
                     /evalue="1.90E-11"
                     /label="pdmC_PP-binding.1"
                     /locus_tag="pdmC"
                     /protein_end="79"
                     /protein_start="9"
                     /score="36.2"
                     /tool="antismash"
                     /translation="DLRALMRAAVGEADDIDLDGDILDSTFTELEYDSLAVLELAARIE
                     TQWGVLIPEDDASGLETPRMFLDYV"
     gene            23865..24326
                     /gene="pdmD"
     CDS             23865..24326
                     /NRPS_PKS="Domain: Polyketide_cyc (11-130). E-value: 6e-16.
                     Score: 50.7. Matches aSDomain:
                     nrpspksdomains_pdmD_Polyketide_cyc.1"
                     /codon_start=1
                     /gene="pdmD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1128:cyclase/dehydrase (Score: 196.3; E-value:
                     1.2e-59)"
                     /gene_kind="biosynthetic-additional"
                     /product="PdmD"
                     /protein_id="ABM21750.1"
                     /transl_table=11
                     /translation="MTQWRTDSVIVIDAPLDVVWDMTNDVASWPELFDEYASAEILERD
                     GDTVRFRLTMHPDADGNAWSWVSERTPDRAALTVNAHRVETGWFEHMNLRWDYREVPGG
                     VEMRWRQDFAMKEASPVSLAAMTERIQSNSPVQMKLIKDKVERAARGAR"
     aSDomain        23898..24254
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_pdmD_Polyketide_cyc.1"
                     /domain_subtype="Polyketide_cyc"
                     /evalue="6.00E-16"
                     /label="pdmD_Polyketide_cyc.1"
                     /locus_tag="pdmD"
                     /protein_end="130"
                     /protein_start="11"
                     /score="50.7"
                     /tool="antismash"
                     /translation="IDAPLDVVWDMTNDVASWPELFDEYASAEILERDGDTVRFRLTMH
                     PDADGNAWSWVSERTPDRAALTVNAHRVETGWFEHMNLRWDYREVPGGVEMRWRQDFAM
                     KEASPVSLAAMTERI"
     gene            24323..24784
                     /gene="pdmE"
     CDS             24323..24784
                     /codon_start=1
                     /gene="pdmE"
                     /product="PdmE"
                     /protein_id="ABM21751.1"
                     /transl_table=11
                     /translation="MIEFLLPVALLGNGLCAGVLTGSVLGVVPYYRTLPEDRYIAAHAF
                     AVGRYDPFQPVCLLVTVAADAVAAAVAPTAAARVLCALAAVLALAVVAISLTRNVPMNR
                     RIKRLDPAAPPAGFSAPAFLRRWAGWNAARTGLTLAALLSNTAALGVLL"
     gene            24805..25830
                     /gene="pdmF"
     CDS             24805..25830
                     /codon_start=1
                     /gene="pdmF"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:O-methyltransferase (Score: 312.2; E-value:
                     7.4e-95)"
                     /gene_kind="biosynthetic-additional"
                     /product="PdmF"
                     /protein_id="ABM21752.1"
                     /transl_table=11
                     /translation="MTEPEGPHAASLRLQSLLDGMRVAKVVQVLAELQVADAVADGPCK
                     PAEIAADVGADPDALYRVLRCAASFGVFTEDEDGRFGLTPMAALLRTGTDDSHRDLFMM
                     AAGDLWWRPYGELLETVRTGRPAAELAFGMPFYDYLGTDPAAAGLFDRAMTQVSKGQAK
                     AILGRCSFERYARIADVGGGHGYFLAQVLRSSPRTEGVLLDLPHVVAGAPAVLEKHEVA
                     DRVQVVPGSFFDALPTGCDAYLLKAILINWPDADAERILHRVREAIGTDRDARLLVVEP
                     VVPPGDVRDYSKATDIDMLAIIGGRQRTVAEWRRLLRAGGFELVGEPTPGRREVMECRP
                     I"
     gene            25868..26608
                     /gene="pdmG"
     CDS             25868..26608
                     /NRPS_PKS="Domain: PKS_KR (10-173). E-value: 8.5e-20.
                     Score: 63.2. Matches aSDomain:
                     nrpspksdomains_pdmG_PKS_KR.1"
                     /codon_start=1
                     /gene="pdmG"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     225.7; E-value: 1.1e-68)"
                     /gene_kind="biosynthetic-additional"
                     /product="PdmG"
                     /protein_id="ABM21753.1"
                     /sec_met_domain="adh_short (E-value: 2e-39, bitscore:
                     126.3, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 1.4e-39, bitscore:
                     127.3, seeds: 47, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 4.1e-09,
                     bitscore: 26.8, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDTSFAGKNALITGGTRGIGRAVALGLARAGANVTVCYRSDAES
                     AAAMEAELAATDGKHHVLQADIGNAGDVRRLLDEVAARMGSLDVVVHNAGLISHVPFAD
                     LEPEEWHRIVDSNLTGMYLVVRAALPLLSEGGAVVGVGSKVALVGISQRTHYTAAKAGL
                     IGFVRSLSKELGPLGIRVNLVAPGITETDQAAHLPPVQRERYQSMTALKRLGQADEVAD
                     VVLFLAGPGARYVTGETVNVDGGM"
     aSDomain        25898..26386
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_pdmG_PKS_KR.1"
                     /evalue="8.50E-20"
                     /label="pdmG_PKS_KR.1"
                     /locus_tag="pdmG"
                     /protein_end="173"
                     /protein_start="10"
                     /score="63.2"
                     /tool="antismash"
                     /translation="ALITGGTRGIGRAVALGLARAGANVTVCYRSDAESAAAMEAELAA
                     TDGKHHVLQADIGNAGDVRRLLDEVAARMGSLDVVVHNAGLISHVPFADLEPEEWHRIV
                     DSNLTGMYLVVRAALPLLSEGGAVVGVGSKVALVGISQRTHYTAAKAGLIGFVRSLSKE
                     "
     CDS_motif       25901..25966
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_pdmG_0001"
                     /evalue="2.60E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="pdmG"
                     /protein_end="33"
                     /protein_start="11"
                     /score="20.1"
                     /tool="antismash"
                     /translation="LITGGTRGIGRAVALGLARAGA"
     gene            26605..26946
                     /gene="pdmH"
     CDS             26605..26946
                     /codon_start=1
                     /gene="pdmH"
                     /product="PdmH"
                     /protein_id="ABM21754.1"
                     /transl_table=11
                     /translation="MTMADSGPVFRVMLRMEIVPGREAEFERVWYSVGDTVSGNPANLG
                     QWLLRSDDEESVYYIMSDWIDEARFREFERSDGHVEHRRKLHPYRVKGSMATMKVVHDL
                     GRAAAEPVR"
     gene            26943..27254
                     /gene="pdmI"
     CDS             26943..27254
                     /codon_start=1
                     /gene="pdmI"
                     /product="PdmI"
                     /protein_id="ABM21755.1"
                     /transl_table=11
                     /translation="MTAGQVRVLVRYQAPGDDPEAVVQAYKLVCEELRGTPGLLGSELL
                     ASTLDEGRFAVLSLWSDAARFQEWEQGPAHKGQTSGLRPFRDTSSGRGFDFYEVVHAL"
     gene            complement(27310..28545)
                     /gene="pdmJ"
     CDS             complement(27310..28545)
                     /codon_start=1
                     /gene="pdmJ"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007:cytochrome P450 (Score: 446.7; E-value:
                     1.1e-135)"
                     /gene_kind="biosynthetic-additional"
                     /product="PdmJ"
                     /protein_id="ABM21756.1"
                     /sec_met_domain="p450 (E-value: 2.1e-16, bitscore: 50.5,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPSSKDAPTVDPRPDVTPAFPFRPDDPFQPPCEHARLRASDPVAK
                     VVLPTGDHAWVVTRYADVRFVTSDRRFSKEAVTRPGAPRLIPMQRGSKSLVIMDPPEHT
                     RMRKIVSRAFTARRVEGMRAHVRDLTSGFVDEMVEHGPPADLIAHLALPLPVTVICEML
                     GVPPEDRPRFQDWTDRMLTIGAPALAQADEIKAAVGRLRGYLAELIDAKTAAPADDLLS
                     LLSRAHADDGLSEEELLTFGMTLLAAGYHTTTAAITHSVYHLLREPSRYARLREDPSGI
                     PAAVEELLRYGQIGGGAGAIRIAVEDVEVGGTLVRAGEAVIPLFNAANRDPEVFADPEE
                     LDLGRTDNPHIALGHGIHYCLGAPLARLELQVVLETLVERTPALRLAIDDADITWRPGL
                     AFARPDALPIAW"
     gene            28679..29023
                     /gene="pdmK"
     CDS             28679..29023
                     /codon_start=1
                     /gene="pdmK"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1225:Polyketide synthesis cyclase (Score: 139.4;
                     E-value: 6.6e-43)"
                     /gene_kind="biosynthetic-additional"
                     /product="PdmK"
                     /protein_id="ABM21757.1"
                     /transl_table=11
                     /translation="MDRFLIVARMSPSSEKEVARLFAESDEGTELPEVAGTVSRSLLSF
                     HGLYFHLTEVEESTDRTLNGIHEHPEFVRLSRQLSGHVQAYDPKTWRSPADAMAREFYR
                     WEAGTGVVRR"
ORIGIN
        1 accaggaaac agcctaggaa cacccgcgta cagcacgagg atcgcctgca tcccgtagaa
       61 gctgaaccgc tcccagatgt cggtgaggaa caacgtcacg aaccagcggg gccgccgggc
      121 cgccgcccct tcggcggccc ggcccgcgtc gatctcgcgg agggacatcg cagtactccc
      181 ttcatgaccg gcctaggacc tgcttcaaag acctcagctg tcgcgcgagt gcctacctgg
      241 cccggcgggg caaagccgaa ggcgagcccc gccgggccag atcgcgaagc gatgcggcac
      301 tcgccaaggc acggtcaggg ggcgagccgc caggcgagcc ccctgggccg ggactttgaa
      361 acactggcta atcgacgacc atggtgtcga ccaggccggt ggtgtgcttg gcggcgcgga
      421 acagcgggtg cgcgagcacc tcgcgcagga acccggtcgt ggtgtggacg ccggggccgg
      481 tgacgcgcag ctcggcgagg gcgcggtcca tccgcgcgat cgcggcgtcc cggtcgcggt
      541 cccagacgac gaccttggcg agcagcgggt cgtagtcggc gggcacccgc agacccggag
      601 cggcgtgggt gtcgatccga gtgaacgggc cgccgggcgc gtcgaacacc tcgatcagcc
      661 ccggcgtggg caggaagccg cggtcggggt cctcgacgtt gatgcggcac tcgatcgccg
      721 cgccacgcgg gcgcacgtcg tccgggccga ccgacaaccg cccgccggag gcggcgacga
      781 gctgctcgcg caccaggtcc acgccggtga ccatctcggt caccgggtgc tcgacctgga
      841 tgcgggagtt gacctccatg aagtagaagc cgtcgtcgcc gaccaggaac tcgtaggtgc
      901 ccgcgccgac atacccggcg gcacgcgcgc cctgcaccgc cgcctcgcac atctgctcga
      961 ccaggccgtc cggcaggccg ggggccgggc tctcctccac cagcttctgg cggcggcgct
     1021 gcaccgagca gtctcgggcc ccgagcgcga gcacggtccc gtgcccgtcg gcgagcacct
     1081 gcacctcgac gtgccgcgcg ccttcgaggt accgctccag gtagacccgg ccgtcgccga
     1141 acagggcgaa cgcggtcgcg cgggtctcgg cgtaggcgcg cagcaggtcg tccgggtcgc
     1201 gcacgatcgt catgccgcgc ccgccgccgc ccgccacggc cttgatgatg accgggtaac
     1261 ccgcctcctc ggccgcgcgc cgggcggact tgccgtcctc caggggacgg acgcggcccg
     1321 gcagcaccgg cagtcccgcc tccacggcgg cctcgcgcgc gagcgacttg tcaccgagct
     1381 gcgccagcac cgacgcgggc ggaccgatga acgtcagccc ctccgactcg cacgcccgcg
     1441 cgaaatcggg gtcctcggac aggaacccgt acccggggtg gaccgcctcc gcgccggtct
     1501 gccgcgcggc ctccaggatg gcgggcgcgt agcggtagct gcgcgcggcg gcgggcgggc
     1561 cgatgtgcac ccgctcgtcg gccagccgca acgccgggga gtcccggtcg gcggtcgagt
     1621 acaccatgat cacgcggatg cccagctcgc ggcaggtgcg cgcgacgcgc agcgcgatct
     1681 cgccgcggtt ggcgatcagc accgaggaga acacgggccc ctccctccgc cgcggctcac
     1741 gcggcctcct cgccggttcc gccgaggtcg tcgtcgatga gcagcagcgg ctggccgtac
     1801 tcgaccggat cgccgtcggc gaccaggacc cggaccaccc ggccggtgcg gtcggcctcg
     1861 atcgggttca tcagcttcat cgcctcgacg atcccgacct gctgcccggc ctggacgagg
     1921 tcgccctcgc gggcgaacgg ctcggcgccg ggctcgggtg cacggtagaa gacgccgacg
     1981 agcggggcga gcagcggccg tcccggcccg tcctcggtgg gtgcagcctc caccggcgcg
     2041 ggcagggccg cggcgacggc ggcgaccgcc gtcccggccg ccgtctcgac caccgcgccc
     2101 gtcgcggcgg cgggctcggg ccagtcgacc tcaacgctca actcgcccgc gcgcaaccgg
     2161 acgctgcgcg gcgggacgcg cgaagcgccc gccagcaccg cgacctggcg gaccagcgcg
     2221 tccagcagct caggcgacgc cgccgcgtca gccggtgccg tcacctcggg cgacgccgcc
     2281 ggttcgtgcg acgccgccac gtcgggcgat gcttcaggcg atgccgtgtc cggcgccgcg
     2341 ggggatgtct cggccatcaa gcctccctgt ctcctcgtga gccaccgggc cgtcggctcc
     2401 gtagcggcgg aaacggccgc gccgtccggc gaccagttcg gcacggtcca gtccggccag
     2461 ttcgtccagc gcctcggcga cggccgcgcg cacgcggccg acggtggcgg gcgggtcggt
     2521 gtgcgcgccc gcgccgggct cggggaccac cccgtccacc acgccgtgcg cgagcagttc
     2581 ccgggcgtcg agccgcagtt cggcggcggc gcgcgccacc gacgcggggt cctggccctt
     2641 ccacaggatc gccgcgcagc cctccgggct gatcaccgag tagacgccgt tggccaggat
     2701 cagcacccgg tcggcgacgc ccagcgcgag cgcgccgccg ctgccgccct cgcccgtcac
     2761 caccgccacg atcgggacgg gcagccgcga catcagccgc aggttctccg cgatcgccca
     2821 cgcctgcccg ttctcctcgg cttcgacgcc gggatgcgcg cccggagtgt cgatcagcgt
     2881 gacgacgggc acgccgagct tggccgccag ccgcatcagc cgggccgcct tgcggtaccc
     2941 ggcgggcgac ggcatcccga agttgcggcg cacccggtcg gcggtgccgc gccccttgtc
     3001 gtgcgcgatc agcatgacgg gccgcccgcc gagccgcccg atgccgccga ggatcgccgg
     3061 gcagtcggcg gccagccggt cgccgcgcag ctcgcggaac tcctccagca tcgtggcggc
     3121 gtagtcgcgg gcgctcggcc gcccggtgtg ccgggccagc cgcaccgccg cgatgccctc
     3181 ccggaccggc agccgcccgg ggtcgcggac gacctcggcg cgcgcctccg ggtcgggcac
     3241 cgcgcgcggc ccggtgcgca gcagcgcgag catccggccg agcgtgctgc gcagcgcggc
     3301 gcgcggcacc accgcgtcca gcaggccctt gccgagcagg aactcggcgg tctggaaccc
     3361 ctccggcagc cgttgcccga tcgtctgctc gatgacgcgg ggcccggcga acccgatgtg
     3421 cgcgcccggc tcggcgagca gcacgtccgg cagcgtcgcg aacgaggccg ccaccccgcc
     3481 gtaggtcggg tcggtgatca gcgcgatggt cgcgatgccc gcctcgtcga gcatcccgag
     3541 cgcctggctg gtcttcacca tctgcatgag cgacagcgcg ccctcctgca tccgcgcgcc
     3601 gcccgacgcg gtgaccagca gcaacggcac ccgcgcccgc aacgactcct cggcggcggc
     3661 ggcgatccgc tcgcccaccg cgctgccgag gctgccgccc atgaactcga agtccatgac
     3721 ggccgcgacc agcgggaagc cctcgatggt gccgcgcacg cacaccacgg cctcgtcgcg
     3781 cccggtcttc gcggcggcgt cgcggagccg ccgcgcgtac ggcacccggt cggtgaagcc
     3841 gagcgggtcg gcgatggtcg gcggcgacgg cagctcccgc acgccggggt cgaacagcag
     3901 ctcgacgcgc tcggccgcgc tcatccgggc gtgccgcccg caccccgcgc acaccttgtg
     3961 catgcgctcg aagcgcggcg cgtacaggat ctccccgcag ccggggcagc gcacccactc
     4021 ggcggcggag ccggtcgtgt cggtcgtcac ggtcaccatc cccgggggaa cgcgcgcagc
     4081 tcggcgcggc gcggctccca ccactcgacg ttgtcgcggt accagcgcac gacctcggcc
     4141 agcccggtct cgaagtccac ccggggccgg tagccgaggc tcgtgcggat cttggtgtcg
     4201 tccagcgcgt agcgccggtc gtgccccttg cggtcggcga cgtgccggac gctgtccggg
     4261 ccgccgccgc acagcgcgac caggcgctcg gtcagctccc ggttggtcag ctccgcgccg
     4321 ccgccgatgt tgtagacctc gccgggcgcg ccgtcctcca gcacccgctg caccgcgtcg
     4381 cagtggtcgg acacgtgcag ccactggcgg cggtgcaggc cgtcgccgaa cagcggcacc
     4441 ggacgtccgg ccagcaggtt ggtgacgaac agcgggatga ccttctcggg gaactggtag
     4501 ggcccgtagt tgttggagca gcgggtgatc atcaccggca gcctgtgggt gtggtggtag
     4561 gcgagcgcga agtggtcgct ggccgccttg gacgccgcgt acggcgagcg cgggtcgacc
     4621 ggcgcggcct cgtcccagga gccggtgtcg atcgagccgt gcacctcgtc ggtggacacg
     4681 tgcacgaccc ggccgatgcc cgccagcacg cagcagtcga gcaggctctg cgtgccgagc
     4741 acgttggtca cggcgaactc gcccgcgctg accagggacc ggtccacgtg cgactcggcg
     4801 gcgaagtgca ccaccgcgtc gtggccgggc agcagctcgc gcagcagcgg gacgtcgcag
     4861 atgtcgccct tgacgaacgt cagccgcggg tcgccgatcg gcaggttgtc ggtgttcccg
     4921 gcgtaggtga gcttgtcgac gacggtgacg agcgcgtccg ccaccgccgg gtagcgcccg
     4981 gccagcaccg agcgcacgta gtgcgagccg atgaaaccgg cgccgccggt caccaggatc
     5041 ctcatcgttc gatcaccacc tcgctgctgt cgcccagcag cagccgccgg gccccgtcct
     5101 gcggcggcag cgcgcgcacc cgcgcgttgc ggccgatcac cgagcggtgc aggtcgcgca
     5161 cgtcgctgac cgacgcgccg tccagcacga tcgagccggc gatcccggcg cgggccagca
     5221 cgcagcccgc gccgatggag gtgccgggcc cgatccggct gtcggtgacg gtgctggcgg
     5281 gcccgatcac cgccgggccc tcgacgcgcg agcgcaccac gcgcgcgccg tcgtccacga
     5341 acaccgcgcc gatcagctcg ctggcctcgt ccaccgagcc cagccgggcg ggcgggatcg
     5401 aggcgagcag ctcgcggttg cactccagca ggtcgtccac gcggccggtg tccttccagt
     5461 agcccgcgaa cacgtgcgcg cgcacgtcct cgccgcgccg gatcagcagc tccaccgcgt
     5521 cggtgatctc cagctcgccg cgcgcactcg gccggatcgc gcggaccgcc gagtggatcg
     5581 cggcggagaa cacgtacacg ccgatcagcg ccaggtcgct gaccggcagt tgcggcttct
     5641 cggccaggcc gtgcacccgg ccgcccgcgc cgacctcggc gacgccgtac tcgcgggggt
     5701 cggcgacggg cccgaccatc agcagcgcgg cgggccgctc ggcggcgaac tgcttcacca
     5761 ggtggccgat gccgccgacg acgatgttgt cgccgaggta catcacgaag tcgtccccgg
     5821 cgaggaagtc ggccgcgatc agcacgcagt gcgccagccc gagcggcgcg tcctgcggga
     5881 tccacgtcac ccgcagcccg aaccgcgagc cgtccccgac cgcgcgccgg atctcctcgc
     5941 cctgcggcga gacgatgatc ccgacctcgc ggacgccggt gtcgcggatc gactccaggc
     6001 agtggaacag caccggcttg ttcgccaccg gcaccaacgg cttggccagg gtgtgggtga
     6061 acggccgcag ccgggtgccc gagccgcccg ccaggaccag cgccttcatc cgcgaccacc
     6121 ccaggtgatc gggatctcgc ggaagctctc cagcaggttg ccgtcgttgc ggcgcaggtc
     6181 ggtcgcgggg atcgccagcc gcaggtcggg cagccgccgg atcagggtgg acagcaccac
     6241 ctccagctcc agccgggcga gcgacgcccc ggcgcagtag tgcgtgccgt ggctgaaggt
     6301 gaggtgcggg ttgtcggtcc gggtgacgtc gaagacctcg gggtgctcga acaccgactc
     6361 gtcctggttg gccgagtcgc ccgccgggat gatgctcgac cccgccggga tggtgacccc
     6421 gccgacctcg acgtcctcgg tgacgtagcg caacatcgtc accgacgagc cgacgatctt
     6481 ccagcggagc agctcctcga cggccgggcg cagcagcgcc gggtccttgc gcaccaggtc
     6541 gagctggtcg ggccgggaca acaacatcgc gatgcagccg ccgatctgca cggcggtggt
     6601 ctcgaagccg accagcacca gcaggcggct ccaccagtgc agctcgtact cgctcagccg
     6661 gccgtcctcg gcgtcggtga ccgcgatcat cgcgctgatc aggtcgtcgg cggggtcggc
     6721 gcgcttggcc tcgatcaggt cgcgcatgta ctcgttgagc cgcgacatgt tccgctcgat
     6781 ctcgtcctgg gtgtagccgc tgatcgacag gaacgcgccg gtccagaccc ggaagcgctc
     6841 ctggtcctcg accgggacgc cgagcagctc gcacaccacc tggatcggca gcgggtaggc
     6901 cagcgcctcg ttcacgtcga tcggcggccg gcgctcggcc atcgcggtga cgagccggtc
     6961 ggtgatctcc tggacgcgcg gccgcagccg ctccacccgc gacggggtga gcgccttcat
     7021 caccagccgc cggatgcggg tgtgctcggg cgggtcgggg tccatcttcg ggtcctggaa
     7081 cagcttgttc ttggcgctga tgcgggccgc gcccggccgg ttcaggttgc ggctgatccg
     7141 gtcgtcggcg agcagcgcgc ggacgtcggc gtaccgcgtc accatccacg cctcgtcgcc
     7201 gctcgggagc acgaccttga cgacgggctg ttcgcggagt ccccggagct ccgcgggcgg
     7261 ttccagcgcg gacggccgcc ggaacgggta cggcaggggc gtggtctcca tcgggctcct
     7321 tcgcgccggc tgcggcaacg tgacagggcg atggtcaccg ggcggcctag aggaccgccg
     7381 gagccgagct tgacggcggg tggaccaccc accgtttcca ctgaggctcc ggcgtcgctc
     7441 tagcccccgc tgtgatcgtg cgggtgaccg accggagctg agaagggacc tcatgcgact
     7501 cggcgtgaac gtcacccacc gcgatccgtg gatcgcccgc gaggccgaac ggctgggcta
     7561 cgaactggcg ctggtccccg aggggttccg ggccgacgcg gtgagcacgc tcggccacct
     7621 ggccgcctcc accgagcgga tcgcgctctc ctgcatcgcg cagatcccgg cgcggacccc
     7681 gagcatggcg gcgatgacgg ccgccgcgct ggacgccctg tcgggcggcc ggttccggct
     7741 cggcctcggc gtctccaacg cctacgccac cgagatctgg cacggcctgc cgttcgcccg
     7801 gccgctggcc cgcacccgcg agtacgtgga gatcgtgcgg gccgcgctga gcggggccga
     7861 ggtccgctac gagggcgagc acttcaccgt cccgctgccc ggccgggacg gcgcgccgct
     7921 gcgcctcgac cccgtcgccg tcccgctcta cctggcggcc gtcgggcccc ggaacctgga
     7981 gctggccgcc gagctggccg acggctggat cgcggtgttc cgcaccgccg agcagatcgc
     8041 cgactccctc ccccacctgg ccgcagggca ggcccgcgac gggttcgagg tgctgctgac
     8101 ggcgcagctc gccgtgggcg acgacgacct cgacgagctg gcggccccgc tgcgcgccca
     8161 tcccgcccgg ttcatgagcc tcgggcaccg cgagcagaac ttctactacc gccaggccgc
     8221 cgcgatgggc tacgagcggg aggccgcgct ggtgcaggac cgcaacgcgg cgggcgacgc
     8281 ggcgggcgcg gccgaggccg tcccgttcgg cttcgtggac gcgacctcgc tgatcggccc
     8341 cgtcgcgcgg atcgcggacc ggatgaagtc ctacgccgcc gccggcgtca ccacgctcgt
     8401 catcaccccg tacgccgccg acgaggccgg gcgcgtcgcc gcgctgcgcg ccgccgcgga
     8461 ggcgctggac cacgccggtg tcggctgacc gccggagagg agacagccat gcccgagaag
     8521 acccgcccga ccgccgcccc ggtcccctcc cgcgacggcc gggaccccgg cccgctctcc
     8581 gtgccgttca accgcccctt caccacgggc cgggaggcgg cctacatgac cgaggccctc
     8641 agctccggca gcaccggcgg cgacggcccg ttcacccggc gcgccgccga gcacctggcg
     8701 cggctgctcg gctcgccccg ggtgctgctc acgacctcct gcacgcacgc gctggagctg
     8761 gccgcgctgc tgctggacct cgcgcccggc gacgaggtgg tgatgccctc gttcaccttc
     8821 acctcgaccg ccaacgcgtt cgcgctgcgc ggcgcggtgc cggtgttcgt ggacgtccgc
     8881 cccgacaccc tcaacatcga cgagcggctc gtggaggccg ccatcaccga gcggacgcgc
     8941 gccatcgtgg tggtgcacta cgccggggtc gcctgcgaga tggacgccat ctccaagatc
     9001 gccgaccggc acggcatccc cgtcgtggag gacaacgcgc acggtctcgg cggcttctac
     9061 cggggccgcc cgctcggctc gctcggcgcg ctcgccacgc agagcttcca cgtcaccaag
     9121 aacgtgcagt gcggcgaggg cggcgcgctg gtggtcaacg acgagcggtt cgccgagcgc
     9181 gccgagatcc tgcgcgagaa gggcaccgac cgcagccggt tcttccgggg ggaggtggac
     9241 aagtaccgct ggcaggacct cggttccagc tacctgccgt cggacgtgct ggcggcgttc
     9301 ctgctcgcgc aactggaggc gttcgccgac atccaggccc gccgcgcgca catctgggcg
     9361 gcctaccacg aacgcctcgc catgtgggcg tcggcgaacg gggtggcgcg gccggagctg
     9421 ccgcccggct gcgtgcaccc cgcgcacctt tactacctgt tgctaccgac gcccgagggc
     9481 gcgaccgcgc tcatcgacga cctcgcccgg cgcggcgtcc aggccacccg gcactaccag
     9541 ccgctgcaca acgcgcccgc cgggctgcgc agcggccgga cggggcccgg tggttgcccg
     9601 gtgaccgagc gggtcgccga cagtctggtc cggctgccgc tgttcgcggg gatggacggt
     9661 cgcgagctgg cgcacatcgt ggattcggtc aaccgccatc cggcccgctg agggccgaac
     9721 ggcggccgac cgggccccgc gcgggcccgt ctcggaggtc agcgcttgcg cgcgatgacc
     9781 agggtgtcga tgtcggtgag cggcacggtg cgggtgacgc cgaagcccgc cgccgtcatc
     9841 cactcccggc agtcgcgggc ggtgtactcg ccgccgccgg ggctgaccag catcatgtgc
     9901 aggctggtca gcaggctgaa gtcgtgggtg cgccgctcgt cgtcgatcat gacgtcgtag
     9961 accagcagct cgccgccgga cggcagcgcc tcgtaggccc gccggaccag cgcggcgcgc
    10021 agctcggggc tccagtcgtg cagcacgtgc ccgaagatca gcacctcggc ggcgggcagc
    10081 gggtcgttga agaagtcgcc gccggtgaag gcgacctggc cggtcagccc gagcgactcc
    10141 atgtgctcgt cgaacaccgt ctgcacggcg ggcaggtcca tcacgcccgc cgccaggtgc
    10201 gggtgcgcct tgcgcagctc ggcggccagg ttgccgcgcg cgccgccgag gtcgacgaac
    10261 gaggcgtgcg cgctccagtc gtaggcgtcg gcgagcgcgg ccccggagaa ctggttgatg
    10321 ccgtccatcg ccgacatgaa ccggcgcagc cgggccggat cggcgtgcat ctcgtcgtgc
    10381 tggtccagct cgtcgtccac ggggtaggcg cggccgccct cgcgcagcag ccgcgtcagg
    10441 tcgccccact gcgcgaactg gtggtcgagc atggtcagga agccgccggt gtaggtgggc
    10501 ttggccgcgt ccaggtaggt gtcggcgacg gcggtgttgt cgtagacgcc gttctcgcgg
    10561 cgcagcaggc cgagcgagac cagcgcgtcg aggaagtcgc gcgccgcgcg cgggtgcagg
    10621 cccagctccc cgcgcagctg cggcccggtc gccggcccct tcgcgaggcg ggtgaacagg
    10681 cccagctcca ccgcgctcag caggaccttc gaccggaagt aggcgatgcc catgcgcagg
    10741 acgtcgtgcg cgttctcagg tgtgccggtc accgtcatcg gacccctctc gaaccggccg
    10801 cggccggcgg ccgggttggc ggcctggttg caggtccgcc catgctgggc ggggcggctc
    10861 gcggggtgct ggacggccgc ttgagggcgc gcgcccgacg ggtcctcaag gccgcctcta
    10921 gccgggtctg tgacgttgcg ggagatcgcc cgcccgacag aacggtggcc cgatggcgaa
    10981 catcctgatc agcacgatgc ccgagagcgg gcacgtgaac ccggcgctgc cgatcgcggc
    11041 ggcgctcacc gcgcgcggcc accgggtccg gtggcacacc ggggccgagt acaccgacac
    11101 gatcgaggcg accggcgcgc ggctcgtccc gatgcggcac gcgccgcgct tccgggaact
    11161 gccgccgcgc cgcgacccga gcagcggatg ggacgcggtg tcggccgtcc tggaacggct
    11221 ctacgtcgcg ccgtccctcg ggcagctccg cgacttccag gagatcctgg cggacttccc
    11281 cgccgacgtg gtgttcaacg agtcgaccgc cgggctcggc ggccacctgc tgcacgacct
    11341 cggcgggccg ccgtgggcgc ggctcggcgt cagcatgccg ccgacgctgc cggactcccc
    11401 gatcccgccg ctgtactcac cccggctgtt caccgacacc cccgagctgc tcgactactc
    11461 cgccgacccg gccgcgatcg cccgctaccg ggagctgaac cacgaggtcg cgcacgtgca
    11521 cctgcggccg ttcaccgacg cgctcaacgc gctgcgcgcc gaggtcgggc tcgcgccgat
    11581 gccgccggga cggaccgcgc tggacgcgac gatctcgccg ttcctgcacg tccagaccgg
    11641 cacgccgacg ttcgactacc cgcgcgacga gctgccgccg cagatccggc acgtcggccc
    11701 gctgctgccg ccgccgtccg gcgcggcgtt cgacccgccg ccctggtggc cggaggtgac
    11761 cagcggtgat cagcccgtgg tgcacgtgac gcaggggacc gtcgccaccg acctggccca
    11821 gctgctcgcg cccacgctgg cgggcctcgc gggcgaggac gtgctggtcg tggcgaccac
    11881 cccagacccg gccgcgctcg ggccgctgcc cgacaacgtc cgggtggccc cctcgatccc
    11941 ctacgcgcac ctgctgccgc tggtcgacgt catgatcacc aacggcggga tcggcggcgt
    12001 gctggccgcc ctggcgcagg gcgtgccgct ggtcgcgacc ggccggaccg aggacaagcc
    12061 cgccatctgc gcgcgcatcg cctacacggg cgtcggcgtg gacctgcgct cggccgcgcc
    12121 ggaaccggac gcggtccgcg cggcggtgaa gacggtgctg tccgacccgt cctaccggcg
    12181 caacgccgag cggatcgggg ccgacttcgc ccggcacgac ccgccggccg aggccgccga
    12241 cctgctcgaa cggctcgcgc gcacccgccg tcccgtcatc gcctgaaagg ccgtgaaatg
    12301 ttcgatcacc agctcgccga ggtgtacgac ctcgtctacc ggcggcgcgg caaggactac
    12361 cgggccgagg ccgccgagct agccgccgcg atccgcgccc gccgtcccgg cgcggcgtcg
    12421 ctgctcgacg tcgcctgcgg caccggcgag cacctggcgc acctggccga gcacttcacc
    12481 gaggccgagg ggctggagct gtcacgcggg atgctcggcg tggcccgcgc caagctgccg
    12541 cacctgacgc tgcacgcggc ggacatgtgc accttcgacc tcggccgccg cttcgacgcg
    12601 atcacctgca tgttcagctc gatcggctac ctggccgaac gcgaccggat gcacgcggcg
    12661 gtggcccgga tggcggcaca cctgacgccg ggcggggtgc tggtgatcga gccgtggtgg
    12721 agcccggaac ggttcatcga caagtacgtc tccggcgagg ccgtcagcga cgccggggtg
    12781 acggtgacgc gggtgtcgcg gacccgacgg ctggacgacg cgcacgccga gatggaggtg
    12841 cacttcgtcg tggccgactc cgcgcgcatc gagcacttca gcgagacgca cgtgctgggc
    12901 ctgttcagcc gggcggagca catggcggcg ttcgcggacg cgggctgcga cgcggagttc
    12961 gtggaggagg ggccgtcggg tcctgggttg tatgtggggg ttcgtacggg ttaggggttg
    13021 ggtgggggac gcggggttga ggttggcggt cgggtgcggg acgcggggct ggggtaggcg
    13081 ctcgggcgcg ggacacgggg ttaggctggg tggccggggt gggaaacccg ggcgggctgg
    13141 gcttgctggg cacctgcacc agccccgcgc gggctagggg ttggtggtcg ggcgcggggt
    13201 tggggtaggt ggtcgggcgc ggggcgcggg gctggggtag gtgggccggt gtgggaaacc
    13261 cgcacaggct ggggttggtg ggcacctgga tgaaccccgc gcggggtaga ggttgctggt
    13321 cgagcgcaga aaacccgtgc ggggctgagc tgcgcggttg gctgtagacc cccactgatt
    13381 gagtcggtgc ggcggcctcg gcgaaagcgg ctgtgtttcc tggggggatg tccccccaga
    13441 cccccacagc gggccgtcac ccgcccggcg ctcgcagggc tcgcgccggg cgggtggcga
    13501 cccttgctag gggcgctgcc cctaggaccc cggcaggggg acgccgtccc cctacaaccc
    13561 cctggcaggg ggctccgccc cctgcacccc taaagagcac ccggctccgc ccgccctacg
    13621 acccctgcac aacctcacac ctacagagcc cacacagttc aggcctgaca gatcttgcac
    13681 agttcacgtc ccgagaacct gatcgttctt gtgctggggt gacgtgaacg ggggcggagc
    13741 ccgatggggg tgtgggggcg cagcccccgc ctcagtcagc aagcacagca gggctccgcc
    13801 ctacaactgt tccggggatg tagggggcgg gccccctgcc ggggtcgtag gggctggccc
    13861 ctgcccggac gacgcacgca cggcgcgagt cctacgagcg ccgggcgggc gacgcccgga
    13921 tgtgggggtc tggggggaca tccccccagg aaacacagcc gctttcgccg cagatctgca
    13981 ccgactcaat cagtgggggt ctacagccga ccaaccgcct caaccccgcg cgggttttcc
    14041 gcacccaacc aacaaccccc agcccgcgcg ggttttccgc acccaaccaa caacccccag
    14101 cccgcgcggg ttttccgcac ccaaccaaca acccccagcc cgcgcggggt tcatccagat
    14161 acccaacaac cccaacccgc gcgggttttc cgcacccgag catctacctc agtcccgcgc
    14221 cccgcgcccc gcgccccgca cccgaccacc aaccccagcc tcgcgcaggg ttgatccaga
    14281 cacccagcaa ccccaacccg cacgggtttc ctgcacaggc ccatcaacct ccaccccgcg
    14341 cgggctttcc gcacccaagt accaacccca gccccgcgcc caaccatcta cctcgccccc
    14401 gagccccgcg cacccgcacc tcgcgcccca cacctcgcgc cccgcgcccg cgcccgacca
    14461 cccccaccta aaccccaaaa gtgaacctcc gccgcctccc cggcaccggc ggccccccgc
    14521 ccagccaccg ttcgagatac tcgcaagcca ccgccacccc atcctcagca cgaatccgct
    14581 cccccacccc cgccgccctc tccgccatgc caccatcccc aacagcccgc gccaccgcat
    14641 ctgccaagcg cggcaccgac agctccggga acggcaccgg atccggtccc gcgcccagcg
    14701 ccgccacccg cgagccccag aacggctggt ccacgaagaa cggcaccacc acgttcggca
    14761 ccccagcacg caacgccgca gccgtcgtgc ccgcgccgcc gtggtgcact acggcggcgg
    14821 tgcgcgggaa cagccagtcg tgcggtgcct cgcggacgac caacagttcc ggcgtggact
    14881 cgatccgctc cgggtccgcc agcagcaccc cgcgcacgcc cgcgcgcgcc agcgcctccc
    14941 ggatcgtcgc cgcggtggcc tccgggtcgg gcgggaccat gctgccgaat cccacgtaca
    15001 ccggcggcgg tccctccccc acgaaccggg ccagttcggg ggcgggttcg cggccgggcg
    15061 cgtccaggaa ccagtagccg gtgatctgcg cgtacctcgg ccagtcgggc gggcgcggca
    15121 ccacggtgga gctgtagccg cacaggcgcg gcatccggtc gcgcgcgaac gagcgcgcct
    15181 ggcccgcgaa ccacggcagc ggcgcgaggc ccagttcggt ggtgcgccac tcgttgacgg
    15241 ccggtcgccg cgtccgccac atcgtctgct gcgcggcggt gtggctgagc cggttgccga
    15301 ggcggcccag cgagcggccg ccgggcacca ggtggctcgg gtacgcgccg gtcgggtggc
    15361 ggggcaggta ttcggccgtg cacgccggga cgccgcgcgc ctcggccacg tggtaggcgt
    15421 tggcgccgag gtgggagaag acgatggcgt cggcgtccgc gcaggcgtgc gcggtggccg
    15481 tcatgaactg ctcggccatc ggcgtgacga acttgcggaa gccgcgcacc gaggcgcgcg
    15541 tgccgccgcc gtcgctcagc cagcgctggc cctcgccgcc gccgagccgt tcgggcatgt
    15601 ccacgtcgag ggggaagaag tcgatcccgg cgacgcccgc cagcgcctcg tagctcttgc
    15661 tggcgacgag gcgcacctcg tggccgcgcc gccgcaggcc ctggcccagc gcggcgtagg
    15721 gctcggtgtc gccccggctg ccgttggtcg caatcacgat ccgcatgtcg gccatgcaac
    15781 ccccggccgc tcaaggccgc ctgtagggcg gctcgaccgg tctctgtgac cttcgcctgc
    15841 ggagacacct tcggagagga gacgcccatg gctcatgccg tcaccgcgcc gccggggacc
    15901 ggcggcgggg agcgggcggc cgcgctggcc gtccgcgggc tcgccaagac ctacccgggc
    15961 ggcaggcgcg ccctcgccgg cgtggatttc gaggtggccg cgggcgaggt gttcgcgctg
    16021 ctcggcccca acggggcggg caagtccacc acgatgcgca tcctgacgac gctctcgcgg
    16081 ccggacgcgg gcaccgcgac catcggcggc gtggacgtcg tccgcgagcc gcagaaggcg
    16141 cggcggctga tcggctacgt ggcgcagcgg tcgggcgtgg acgcctccgg caccggccgc
    16201 gagaacctga cgctccaggg gcggctgcac ggcctgtcgg gccggacgct ggcggcccgc
    16261 gtggacgcgc tgctggagac cgtcgggctc accgagatcg ccgaccgggg cacccgcgag
    16321 tactcgggcg gcacccgccg caagctggac atcgcgatgg ggctggtgca cgagccccgc
    16381 gtgctgttcc tggacgagcc caccaccggc ctggacccgg aggtgcgcgc cgagatctgg
    16441 gagcacatca cgggcctggc gggcgcgggc gcgctcacca tcctgctcac cacccactac
    16501 ctggaggagg ccgaccggct ggcgggccgg gtcgcgatcc tggaccgcgg cacgatcgtc
    16561 gcgcagggca cgcccgccga gctcaagggc gacctgcgcg gcgacgccat ccacgtggag
    16621 gtgctggacc cggcggcggc cgagcccgcc cgccgcgtgc tggcggggct ggcgcgggtc
    16681 cgggaggtga cggtggacgg cgtgacggtg cgcgcgctgg tcgaggacgc ggccggggcc
    16741 gtcccgctcg tcctggcggc gctgaccgag cgcggggtga ccgcgtcctc ggtcgcggtc
    16801 gcccgcccgt cgctggacga cgtctacctg cactacgcgg gccgctcggc gaaggaggag
    16861 agggcatgag caccatcgcg agccagtcgt ggttcatgac ggcccggctg ctgcgcggga
    16921 cggtccgcga gccgctgttc ctgatcatcg ggctggtgca gccggcgatc tggctgctga
    16981 tcttcgggca gctgttctac cgggtgaccg acctccaggg cttcggcgac gggcggccct
    17041 acctggacta cctcaccccg ggcgtcgtcg tcatgatggc gctgacgcgc ggcgcctgga
    17101 gcggcgggaa cgtgctggag gagctggacc acggggtgct ggaccggttc ctggtgtcgc
    17161 cggtgtcgag ggcggcgctg atcgccgggc acctgtgcca gcaggcgatc acgatcatgg
    17221 cgcaggcggt gctcgtgctg gggctggcgc tggcgatggg cgcgcggttc gcgggcgggc
    17281 cggtcggggc gctggtgctg ctgctggcgg cgatcctgat ggtgctggcg gtcgggtcgt
    17341 tgtcgatgtc gttcgcgctg gtcatccggc gcagccagtc gctgacggcg gtgatccagt
    17401 tcgtcctgct gccgctggtg ttcctcagct cggcgttcat ggaccagagc ctggcggccg
    17461 ggtggatccg cacgatcgcc cgcttcaacc cgatcgactg ggcggtcctg gcgggccgct
    17521 cggcgctggc cgagcaccct gactggcagc tcatcgggac gcggctgttg tggctggccg
    17581 tcctcgcggc gctgtgcgcg ctggtggcag tccgctcgtt ccgctcctac cagcggtcgt
    17641 tgtaggcccg gacgcctacg gccccgcctc ctcggaggcg gggccgttga cgtgcggggc
    17701 ctgtcagacg tccaggtcga gacggacgcc gtagtcgcgg agccaggtgt cgagttgcag
    17761 gatcagctcg acgttggtgc gcccgcgcca gccctcggcg aggctgttcg ggtcgtcgag
    17821 cagctcgcgg gcgccctgcg ggtccaggaa cggcgcgacg ggcgcggacg ggtccgccag
    17881 gatctccgac agctcggtgc gcagcacctt ggcgtagccg gggtccacgc tcaccgggaa
    17941 cgggctcttc gggcgcttca gcaccgactc gggcagcagg tcggcgacgg cggcgcgcag
    18001 caggctcttc tcgcggccgt cgaacgtctg gaggtgccag ggcgtgttga acgcgtactg
    18061 gagcagctcg gggtcgcaga acgggacgcg cgtctccagc cccacgtagg cgctgagccg
    18121 ctcgtcgttg cggatgaggg tctcggggta gcgggtcagg tgggtgtagg tgatctcccg
    18181 catccggcgt tcctgcgggt cggcctcgcc gacgtgcgga acctcggcga gggcctcgtg
    18241 gaagcggtcg cggacgtagc cggggatgtc cagggaccgg cgcagcgccg gggcgagcag
    18301 cccgttgccg agcccgtcgg ggcaggcgcg gcgctgggcg agcgcgaccc acgggaaggt
    18361 gtcggcgttg gcgaactcgg ggtcctgcac ccaggccggg ccgccgaaca acgagtcggc
    18421 gagctggccg gtgagcgcga cggtggagtg ctcggccgcc gcgcggtaca gcaggtacag
    18481 gccggtctgc atgtcgccga gcgggctcgg caggtcgcgg gcccggatcg tctccgcgcg
    18541 catgacgggg tcgagcaggt cgctcgtgtc cagcatgacg tcggtgtgct cggagccgac
    18601 gtgcgccacg aggtccttca cgtacggcgc gtccagcgag gtgcggacct ggtcgggcac
    18661 gaagttctcg gcgaggcccg cgtagtccac ggtgaaggtg cggaccgggc cctcgccgcg
    18721 ctcggcgagg atgtgcgcgg cgatcgcggt gaggccgctg gagtccaggc cgcccgacag
    18781 cagcgagcag accggcacgt cggcgcggag ctggcggccg atcgactcct ccaggagccg
    18841 ccggacgttg gcgatggtgg cgtcccggtc gtcggtgtgc tcgcggccct ccaggcccca
    18901 gtacttctcg gtgacgatgc cgcgctcgcc gatccgcacc acgtgcccgg cgcgcacctc
    18961 gtgcatgccc ttgaacacca ccgcgccggg cgtcccggcc tgcgacagca gctcgcggaa
    19021 cccgtcggtg tcgaccaccg cgtccaccca cgggtgcgcc agcagcgcct tgggctcgga
    19081 cgcgaacagc acgccggtcg gcgtcggata gtagatgacg ggcttcgcgc cgagctggtc
    19141 gcgggcgagc agcagttcct cgctgcgcgg gtcccagacg gcgaacgcga agatgccgtt
    19201 cagcttcgcg gcgcagcccg cgccccactc caggtacgcc tccaggatca cctcggtgtc
    19261 gctgcgggtg cggaagcggt ggccgcgcgc cgccagctcg gcgcgcacct ccccggcgtt
    19321 gtagatctcg ccgttgaagg ccagcaccgc cagctcgcgg ccgtcgtgct cggcgcgcat
    19381 gggctggcgg ccgcccttgg ggtccagcac cgccaggcgg cggtgcccga acgcggcgcg
    19441 ctcgctcagc cagacctcct cggcgtcggg gccgcggcag gccatcgtcg cggtcatcgt
    19501 gcgggtcgtg gcgccctcgc ggcgcaggtc gcgctcgtag tccacccagc cggcgaatcc
    19561 ggacatcggt cctccttgct ctcacacgac ccagcggccg tcggacatga tcactcggtc
    19621 ggccatctcg cccaggtgcc gccaggccag cacccggcgc gggacgacga acaggtacac
    19681 gcagcccggc acgcgtccgg ggtcgagggg cagcgccgcc agcgcggcgc ggtcggcgtc
    19741 gggcacgtcg gcggcctgga cgagggcggc ctcgccgtcg agcagcacga cgtcctcggc
    19801 ggtgccgaac gccagccgga ccgtgccgtt ggccgccagg ttgcgggcgg tcagggaggc
    19861 cgccttggtg gacatcacga cgcgcccgcc gtcccagacg caggcgagcg gcaccaggtg
    19921 cgcgcccttc tccccaccgg tcgcggccca ggtgtgccgg acggtggcga gcaggtccag
    19981 cgcgtcctgc ttacgttgcg cgggcgatcg gggcggcgcg ccggtgacgc cgcgcgcgct
    20041 cacgccatca ccgccgtgac gttgccgacg aacgcggcga gcgcgagcgc cgtccgcgcc
    20101 aggttccagc ggccccagcg gcggcgcggg tcggcccagt cggcgggcat cgcgttctcg
    20161 tccagcgcct tgacgcgctt gttgatcggc acgttctgcg tctgcgacac cagcgcgacc
    20221 ccggccagca gcagcgccga caccccgtac agcggctgcg cgacaccgct cgcagtgacc
    20281 gccaggacgg tgtcggccag cgtcgacgac aggaccagga tcggcatcat cgggtcgtag
    20341 gcgcggccga cgagcttgtg cgcggcgacg tactggccgg gcgccatcgc ctggagcgcg
    20401 ggccagacgc cgaccgcgtg cgtgaacagc accccggcgg ccagcccgct gctcaccagc
    20461 acggcgccgc cgagaatctc aggcaccaat gtgaacactc ctctcccctt cgccgccgca
    20521 gtctccgccc ggcccctaga ggggcgcttg aaggccgctg acggcgcgct ccgttcaagg
    20581 gcccttcgag gacgccgcga gcaccgccgt cgacgcttcg agaccggagg ccaaggccgt
    20641 cgatgggagc acccctggtg agcgagaacc gaccgaccaa gatcaccgcc gcggacgtgg
    20701 cgccgaaccg gcggcgcggc ggcgacctgc gcgtgctgct cggcccgaag accgtcggca
    20761 ccacgaccgg cttcatgggc cggctgtcgc tggagcccgc cgagttcgtc tcggagcact
    20821 accaccccta ctcggaggaa ttcctgtacg tcgtacgcgg tgaggtgctg gtccgggtgg
    20881 acggcgagcc ggtcgtgctg gagccgggtg ccgcgctgtt cgtcccgatc ggggtgcggc
    20941 accgggtcga gaacgtcggc gtcgggccgg ccgaggtggt cttcaccctc ggcccgctgg
    21001 ccccgcgccc cgagctcggc cacgtcgaca ccgaggagct gcccgccccc gacgagcagg
    21061 ggctcgacgt cgggggccgc acgtgagccg accgcagggg ggcgggccgc gccgcgtcgc
    21121 gatcaccggc atgggggtgg tcgcgcccgg cggctcgggc cgcaaggcgt tctggaacct
    21181 gctgaccgac ggccgcaccg cgacccggaa gatctcgctg ttcgacccgg cgggcttccg
    21241 gtcccggatc gccgccgagt gcgacttcga ccccgccgcc gaggggctga cgccccgcga
    21301 ggtccggcgc atggaccggg ccgcgcagct cgcggtggtg tcggcgcgcg aggcgctcgc
    21361 cgacagcggg ctggtggcgg gcgagggcga cccggcgcgg ttcgcggtgt cgctcggcag
    21421 cgccgtcggc tgcacgatgg ggctggagga cgagtacgtc gtggtcagcg accagggccg
    21481 cgactggctg gtcgaccact cctacggcgt gccgcacctg taccggcacc tggtgcccag
    21541 ctcgctggcg gccgaggtcg cctgggcggg cggggccgag ggcccggtca cgctgatctc
    21601 gacgggctgc acctccgggc tcgacgcggt cgggcacggc gcgcgcgtca tcgccgaggg
    21661 ctcggcggac gtggcgctcg ccggggccac cgacgcgccc atctcgccga tcacggtggc
    21721 gtgcttcgac gccatccggg cgacctcgcc gaacaacgac gaccccgagc acgcgtcccg
    21781 gccgttcgac cgggagcgca acgggttcgt gctcggcgag ggcgcggcgg tgttcgtcct
    21841 ggaggagctg gagcacgccc gccgccgggg cgcgcacgtc tactgcgagg tcgcggggta
    21901 cgccacgcgc ggcaacgcct accacatgac gggcctgaag cccgacggcc gcgagatggc
    21961 cgaggcgatc agggtggcga tggacgccgc ccgggtcgcc ccggccgacc tcgactacat
    22021 caacgcgcac ggctcgggca ccaagcagaa cgaccggcac gagacggccg cgttcaagcg
    22081 cagcctcggc gagcgcgcct acgagctgcc ggtcagctcc atcaagtcga tggtcgggca
    22141 ctcgctcggc gcgatcggct cgatcgagct ggccgcgtgc gcgctggcga tcgagcacgg
    22201 tgtggtgccg ccgaccgcca acctgcacaa cgccgacccc gaatgcgacc tggactacgt
    22261 gccgctggtg gcgcgcgagg gccgcatccg cacggtgctg agcgtgggca gcggcttcgg
    22321 cggcttccag tccgccaccg tcctgcggga ggccgcgtga gcgtcctgac ggcggacgcg
    22381 ccggcggtca ccgggatcgg cgtggtcgcg ccgaccggga tcggcgtcga ggagcactgg
    22441 gcggcgacgt tgcgcggcgt cccggtcatc gggccgctga ccaggttcga cgcctcgcgc
    22501 tacccgtcgc cgttcggcgg cgaggtgccc gggttcgacg ccgccgagcg cgtcccgggg
    22561 cggctcatcc cgcagaccga ccactggacg cacctggcgc tggccgccac cgacctcgcc
    22621 ctcgccgacg cgggcgtggt cccggccgag ctgcccgagt acgagatggc ggtggtgacc
    22681 gccagctcgt cgggcggcgt ggagttcggg cagcgcgaga tccaggcgtt gtggcgggac
    22741 gggccccggc acgtcggggc ctaccagtcg atcgcctggt tctacgcggc gacgaccggc
    22801 cagatctcca tccggcacgg gatgcgcggc ccctgcggcg tcgtggtcgc cgagcaggcc
    22861 ggggcgctgg agtcgttcgc gcaggcccgc cgctacctgg cggacggggc gcgggtggtg
    22921 gtgtccggcg gcaccgacgc gccgttcagt ccgtacggcc tgacctgcca gctcggcagc
    22981 gggcggctta gcacgggtgc cgacccggcc cgcgcctacc tgccgttcga cgccgccgcg
    23041 aacggcttcg tgccgggcga gggcggcgcg atcctcatca tcgagcaagc cgccaccgcg
    23101 caggaccgct cctacgggcg gatcgcgggc tacgcggcga ccttcgaccc gccgccgggc
    23161 tcgggccgcc ctccgacgct ggagcgagcc gtgcgcgccg ccttggacga cgcccggctc
    23221 acacccgccg acgtggacgt ggtgttcgcc gacgcggcgg gcgtcccgga tctggaccgc
    23281 gcggaggccg acgcgatcgg cgcggtcttc gggccgcgcg gcgtgcccgt caccgcgccc
    23341 aagagcctga ccggccgcct gtacgcgggc ggccccgcgc tcgacgccgc gacggcgctg
    23401 ctggccatgc acgactcggt gatcccgccg acggccggcg gcgcggacgt cccgcccggc
    23461 tacgcgctcg acctggtcgg cgcggaaccg cgcccggccc ggctgcgcac cgcactgatc
    23521 atcgcccgcg gctacggggg cttcaacgcc gccctggtgc tgcgcggccc gaacacctga
    23581 caacgacccg agaggacgga cgagatggca acccgcgaac gcaccatcga cgacctgcgc
    23641 gcgctgatgc gcgccgccgt cggcgaggcc gacgacatcg acctggacgg cgacatcctc
    23701 gactccacct tcaccgagct ggagtacgac tcgctcgccg tgctggagct cgcggcccgc
    23761 atcgagacgc agtggggcgt gctgatcccc gaggacgacg cgtccgggct ggagaccccg
    23821 cgcatgttcc tcgactacgt gaacgggcgg gcggtggccg agcgatgacg cagtggcgca
    23881 ccgacagcgt gatcgtgatc gacgcgccgc tcgacgtcgt ctgggacatg accaacgacg
    23941 tcgcctcctg gccggagctg ttcgacgagt acgcctcggc cgagatcctg gagcgcgacg
    24001 gcgacaccgt ccgcttccgg ctgacgatgc accccgacgc cgacggcaac gcctggtcgt
    24061 gggtgtcgga gcgcacgccc gaccgcgccg cgctcaccgt caacgcgcac cgcgtggaga
    24121 ccggctggtt cgagcacatg aacctgcgct gggactaccg cgaggtgccc ggcggcgtgg
    24181 agatgcgctg gcggcaggac ttcgcgatga aggaggcgtc gccggtgtcg ctggcggcga
    24241 tgaccgagcg catccagagc aactcccccg tccagatgaa gctgatcaag gacaaggtgg
    24301 agcgggcggc ccggggcgcg cggtgatcga gttcctgctc ccggtcgcgc tgctcggcaa
    24361 cgggttgtgc gcgggcgtgc tgacgggcag cgtcctcggc gtcgtgccgt actaccggac
    24421 gctgcccgag gaccgctaca tcgccgcgca cgccttcgcg gtcggccgct acgacccgtt
    24481 ccagccggtg tgcctgctgg tcacggtggc ggccgacgcg gtcgcggcgg cggtcgcgcc
    24541 gaccgccgcc gcccgggtgc tctgcgcgct cgccgccgtg ctcgcgctgg cggtggtggc
    24601 gatctcgctc acccgcaacg tgccgatgaa ccgccggatc aagcggctgg acccggccgc
    24661 gccgcccgcc gggttcagcg cgcccgcgtt cctgcgccgc tgggcgggct ggaacgcggc
    24721 gcgcaccggc ctgacgctgg ccgccctgct cagcaacacg gccgccctcg gcgtgctgct
    24781 gtgaccgatc gggaagggag ggacatgacc gaaccggaag gaccgcacgc cgcgagcctg
    24841 cggctccaat ctctgctgga cggcatgcgc gtcgccaagg tcgtgcaggt gctcgccgaa
    24901 ctccaggtgg ccgacgcggt cgccgacggc ccctgcaagc ccgccgagat cgccgccgac
    24961 gtcggcgccg accccgacgc gctgtaccgg gtgctgcgct gcgccgcctc gttcggggtg
    25021 ttcaccgagg acgaggacgg ccggttcggg ctcaccccga tggccgcgct gctgcgcacc
    25081 ggcaccgacg acagccaccg cgacctgttc atgatggcgg cgggcgacct gtggtggcgg
    25141 ccgtacggcg agctgctgga gacggtgcgg accggccgcc ccgccgccga gctggcgttc
    25201 gggatgccgt tctacgacta cctcggcacc gacccggccg ccgccgggct cttcgaccgc
    25261 gcgatgacgc aggtcagcaa gggccaggcg aaggcgatcc tcggccgctg ctcgttcgag
    25321 cggtacgcgc ggatcgccga cgtgggcggc ggccacggct acttcctcgc gcaggtgttg
    25381 cgcagcagcc cgcgcaccga gggcgtgctg ctggacctgc cgcacgtggt ggccggagcc
    25441 ccggcggtgc tggagaagca cgaggtcgcc gaccgcgtcc aggtcgtccc gggcagcttc
    25501 ttcgacgcgc tgcccaccgg ctgcgacgcc tacctgctga aagcgatcct catcaactgg
    25561 cccgacgccg acgccgaacg catcctgcac cgggtgcgcg aggcgatcgg caccgaccgc
    25621 gacgcgcggc tgctggtggt cgagcccgtc gtcccgcccg gcgacgtccg cgactacagc
    25681 aaggccaccg acatcgacat gctcgccatc atcggcgggc ggcagcgcac cgtcgccgag
    25741 tggcggcggc tgctgcgcgc gggcggcttc gagctggtgg gcgagcccac gccgggccgc
    25801 cgcgaggtca tggagtgccg ccccatctga acccgtccca cccgtcgccc acatccaggg
    25861 agaacgcatg accgacacat cgttcgccgg caagaacgcg ctgatcaccg gcggcacccg
    25921 gggcatcggc cgggccgtcg cgctcggcct ggcccgcgcc ggggccaatg tcaccgtctg
    25981 ctaccgcagc gacgccgagt ccgccgccgc gatggaagcc gagctggccg ccaccgacgg
    26041 caagcaccac gtgctccagg ccgacatcgg caacgccggg gacgtccgcc gcctgctgga
    26101 cgaggtcgcc gcccgcatgg gctcgctcga cgtagtcgtg cacaacgccg ggctgatcag
    26161 ccacgtgccg ttcgccgacc tggagcccga ggagtggcac cggatcgtcg actccaacct
    26221 gaccggcatg tacctggtgg tgcgggccgc gctgccgctg ctgtcggagg gcggcgcggt
    26281 cgtcggcgtc ggctccaagg tcgcgctcgt cggcatctcg cagcgcaccc actacaccgc
    26341 cgccaaggcc gggctcatcg ggttcgtgcg ctcgctcagc aaggagctgg ggccgctcgg
    26401 catccgggtc aacctggtcg cgcccggcat caccgagacc gaccaggccg cgcacctgcc
    26461 ccccgtgcag cgcgagcgct accagagcat gaccgcgctc aagcggctcg gccaggccga
    26521 cgaggtcgcc gacgtggtgc tgttcctcgc cggtcccggc gcgcgctacg tcaccggcga
    26581 gaccgtcaac gtggacgggg ggatgtgacc atggccgaca gcggcccggt gttccgggtg
    26641 atgctccgga tggagatcgt cccgggcagg gaggcggagt tcgagcgggt ctggtactcg
    26701 gtcggcgaca ccgtcagcgg caaccccgcc aacctcggcc agtggctgct gcgcagcgac
    26761 gacgaggaga gcgtctacta catcatgagc gactggatcg acgaggcgcg gttccgcgag
    26821 ttcgagcgca gcgacggcca cgtcgagcac cgccgcaagc tgcacccgta ccgggtgaag
    26881 ggcagcatgg cgacgatgaa ggtcgtgcac gacctcggcc gcgcggcggc ggagccggtc
    26941 cggtgacggc cgggcaggtg cgggtcctgg tccgctacca ggctccgggc gacgaccccg
    27001 aggccgtcgt ccaggcgtac aagctggtct gcgaggaact gcgcgggacg cccggcctgc
    27061 tcggcagcga gctgctggcg tccacgctcg acgagggacg gttcgcggtg ctgagcctgt
    27121 ggagcgacgc cgcgcggttc caggaatggg agcagggccc ggcgcacaag ggccagacgt
    27181 ccggcctgcg cccgttccgg gacacctcct cggggcgcgg cttcgatttc tacgaagtgg
    27241 tgcacgccct gtaagaacaa cgaagggccc ggcacgcgca tggcgtgccg ggccctttca
    27301 catccgtgcc taccaggcga tgggcagcgc gtccggccgc gcgaacgcca agccgggccg
    27361 ccaggtgatg tcggcatcgt cgatagcgag acgcagcgcg ggcgtccgct ccaccagcgt
    27421 ctccagcacg acctgaagct ccagccgggc gagcggcgcg cccaggcagt agtggatgcc
    27481 gtggccgagc gcgatgtgcg ggttgtcggt acggccgagg tcgagttcct cgggatcggc
    27541 gaacacctcc ggatcgcggt tggcggcgtt gaaaagcggg atgaccgcct cgcccgcgcg
    27601 cacgagggtg ccgccgactt ccacatcctc gaccgcgatg cggatcgcgc ccgcgccgcc
    27661 gccgatctgc ccgtaccgta gcagttcctc aacggccgcc gggatacccg acgggtcctc
    27721 gcgcagccgc gcgtaccgcg acggctcgcg cagcaggtgg tagaccgagt gcgtgatcgc
    27781 cgccgtggtg gtgtggtaac ccgccgccag cagcgtcatg ccgaaggtga gcagttcctc
    27841 ctcgctgagg ccgtcgtcgg cgtgcgcgcg gctcagcaac gacagcaggt cgtcggcggg
    27901 cgcggccgtc ttggcgtcga tcagctcggc gaggtagccg cgcagccgcc cgaccgcggc
    27961 cttgatctcg tcggcctgcg cgagagcggg cgcgccgatg gtgagcatcc ggtcggtcca
    28021 gtcctggaag cgcggccgat cctccggcgg aacgcccagc atctcgcaga tgacggtgac
    28081 cggcagcggc agcgccaggt gcgcgatcag gtcggcgggc gggccgtgct cgaccatctc
    28141 gtccacgaac cccgacgtca ggtcgcgcac gtgcgcgcgc atcccctcca cacgacgggc
    28201 ggtgaacgcg cgagacacga tcttgcgcat cctcgtgtgc tcgggcgggt ccatgatgac
    28261 cagcgacttg gagccgcgct gcatcgggat caggcgcggc gcgcccggcc gggtcaccgc
    28321 ctccttgctg aagcgccggt ccgaggtgac gaaccggacg tcggcgtagc gcgtcacgac
    28381 ccacgcgtgg tcgccggtcg gcagcaccac cttggcgacc gggtcggacg cgcgcaggcg
    28441 cgcgtgctcg cacggcggct ggaaggggtc gtccggccgg aacgggaagg ccggcgtgac
    28501 gtcggggcgg gggtcgacgg tcggggcatc cttcgaggag ggcatacgcc aggcttgcaa
    28561 ggacgcctcg aagcgggctc aacgcgggct cgctccaccg tccttcgagc ggcccccgag
    28621 ctgcggtgac cacactctgc ggctaccggc tcacagcccc gaccgaggga tggttcccat
    28681 ggacaggttc ctgatcgtcg cccgcatgtc cccctcgtcg gagaaggagg tggcgcgcct
    28741 gttcgccgag tccgacgagg gcaccgagct gccggaggtg gccgggacgg tcagccgcag
    28801 cctgctgtcg ttccacggcc tgtacttcca cctgacggag gtggaggaga gcacggacag
    28861 gacgctgaac ggcatccacg aacaccccga gttcgtccgg ctgagccgcc agctgtccgg
    28921 tcacgtccag gcgtacgacc cgaagacgtg gcgctcgccc gccgacgcca tggcccgcga
    28981 gttctaccgg tgggaggcgg ggaccggcgt cgtgcgccgc tgacccgtcc cgagtcccac
    29041 cggtcgcagg ttgctcactc tccgttgact cccttcctcg atagcgtcat cgttggtggc
    29101 ccacctggac gacggagcca tctgagggga agcgttgggt accgatactc tcccgagact
    29161 caccgacgcc ggagagctcg tgctcccggg cagagacggc ggagaggtcg gcatcgacct
    29221 gttcgccctc ggggagctgg gggtcgcggg gcggggcgcg ccgcgggcca tgtacgcgct
    29281 gctggcgggc ctgctgtcgg aggagtcctg cccggacgtg cgcatcattg gcgcgggcgc
    29341 ggacctgtcg ctgctgaccg gcctgccgat cggccggttc cgggtgccgg gcccgcgcga
    29401 gttccgggcg ctgtccacgc acgcggaggc gctgcgcgtg ttgtgcgacg agcgggcgcg
    29461 gatcgaggag ggcgacggcc cgtcgccgta cctgatcctg ctgtcgttca ccaagtgcga
    29521 cgtgcagcgc gacctgccgg acctggtcgc gccgcgacgg ggcaggcggc gcgtggcggc
    29581 gatcctggtc ccgtgcgcgc cgcacgggct gacctgcacc ctggacgagg acggcggcat
    29641 cctggaggtg cagggcagcg gcccggacga ggaactgcgc gcgagcctcg cccgggtgcg
    29701 gttcgcgcaa ctcgacctgg acgagggcgc ggcgctgttc gtggagtacc tggccggggc
    29761 gatcgcacgc tacgagaccc acaacttctg ggacgacctc ccctgatccc cgccgccccg
    29821 gccagaaggc ggctcaggta ccggcggcct cggccgtggc ctcgaccgcg gcctcctctt
    29881 ccttgcgccg ggcctcccgc tcgtgggcct cgacgatgtg ccggacggcc tcgtcggggt
    29941 cgtcggtgag gtggaacagg tcgaggtcgg cctcggcgat cttgccgccg gtcagcatcg
    30001 tcgccttgat ccactcgacc aggccgcccc agaactcggt gcccatcagc acgatcggga
    30061 accgggtgat cttcttggtc tgcaccagcg tgatggcctc gaacagctcg tccagcgtgc
    30121 cgaagccgcc cggcagcacc acgaacgcct gcgagtactt cacgaacatc gtcttccgca
    30181 cgaagaagta acggaactcc agcccgatgt cgatgtactc gttcatgctc tgctcgaacg
    30241 gcagctcgat gccgaggccc accgacaggc cgccgtcgtc gtcgcagccc ttgttggcgg
    30301 cctccatgat gcccggaccg ccgccggtga tgaccgcgta gcccgcctgg tgcagcttcg
    30361 cgccgacctc cacgcccagc ttgtactcgg gcgagtcggg cttggtgcgg gcgctgccga
    30421 agacgctgac ggcctggggc agctcggcca gcaggccgaa gccctccacg aactcggcct
    30481 ggatgcgcaa cacccgccac gggtcggcgt gcagccagtc cgaggggccc cggctgtcca
    30541 gcagccgctg gtcggtggtg gtctgcggga gggcgcggcc gcgcagcgtc gcgggcccct
    30601 ggcggtgcgt gcgggactct tcggatgtca tgccgtcacc gtaaccggcc cgccgggacc
    30661 tggtcccgcc gttcagccga gccacgacat catccggcgc tcgcactcgg cgatcagggg
    30721 cagctcgacg tactcgtcct tagtgtgggc gagggtcggc tcgccgggcc cgtagttgac
    30781 ggcgggcacg cccagctcgg cgaagcgcgc gacgtcggtc cagccgagct tggcgcgcac
    30841 cgccgcgccg ctctcggcga cgaacgcggc cgccgccggg tggttcaggc cgggccgggc
    30901 cgccggggcc gcgtccacca cgcgcagctc gaagcccgcg aaccgctcgc gcagcagcgc
    30961 ctccgcctcg gccaccgact tgtcgggcgc gaaccggtag ttgacggtga cgacacactc
    31021 gtcggggatc acgttcccgg ccacgccgcc gctgacgaac accgcgttca ggccctcgtg
    31081 gtactccagg ccgtcgacct cgggcttggt gggctcgtag gcgcgcagca cgtccaggat
    31141 cccggccgcc ttgtggatgg cgttggagcc catccaggcg cgggcgctgt gggcgcgctc
    31201 gccgcgcgcg acgacctcca cgcgcatggt gccctggcaa ccgccctcga tcaggccgcc
    31261 ggtcggctcc agcagcacgg cgaagtcacc ggccagcagc tcggggcggg tctcggcgat
    31321 gcgcttgagg ccgttgcgct cggcctcgac ctcctcgcac tcgtagaaca cgtaggtgac
    31381 gtcgcggctg ggctcggtga gcgcggcggc cagcttgagc tggacggcga cgccgctctt
    31441 catgtcggtg gtgccgcagc cgtacaggcg gtcgccctcg acgcgggagg gcaggttgcc
    31501 gttcagcggg acggtgtcca ggtgcccggc gagcacgacg cgctcgtcgc ggcccagctc
    31561 ggtgcgcgcc acgaccgagt cgccgtcgcg gacgaccgtc aggtggggca gcgcgcgcag
    31621 cgcctcctcg acggcgtcgg cgagggcttt ctcgtcgccg ctcaccgact cgatgtccac
    31681 gatcgccgcc gtcaggtccg ccacgtccga gaagaggtca agccgcatgt cagcagggta
    31741 cttgaccttg acgcgacggc agggcgttgg atgggtggcg tgctgaggat cggagagatc
    31801 gccgagctgg tcggcgtgac gcaacgcacc atccgccact accaccacgt cgggctgctg
    31861 cccgaacccg cgcgggacgc ctccggctac cgctcctacg ggatggacga cgtggtgcgg
    31921 ctgatccgcg tccggcaact ggcgtcgctg ggcctgtcgc tggcggaggt cgccgacgcg
    31981 ctcgccgacg gctcggccga cctcaccgag gtgctgaccg acctggacgc cgagctggcc
    32041 cgccgggagg ccgagatccg gcggcagcgc gagacggtgg cgcggctgct ggcgggaggc
    32101 ggcgagccgg gcctgtcccc cgaggtgacg gcggcgctgc acgagctgtc cagcgccgtg
    32161 gacccggaga tcatcgagct ggagcgcaac gccgcccgcc tgctggagca cgtcgcgccc
    32221 gccgcgtggg ccgccgggat ggccgggatg tacgggcagg tggccgccga ccccgaccgc
    32281 accgcccggc tggccgcgct gagccgccgg ttcatggacc tggccgacga cgaggtggag
    32341 gaggtggcgg cggggttcgt cgaggagctg ggcgcgctgc tgcccgcgcc cgtccccgac
    32401 caggcggacg acccgctcgg cggcctgctg ggcgagctga tgatcgccga cttctcaccc
    32461 gcccagcagc gcgtgatcag gctggcggcc gaacgcctgc aggaaggacc cctttgaaga
    32521 tcttcaccga cccctgcgcg gtgcccctcc ccaaaggcga ccgctcaacg gtgaccaccg
    32581 tgctcaacgc cctacgaacc cccgccgtca cccactgacg ccgtgatccc gcaagagctc
    32641 gttcagcgcg gccttgtcat gccgccgtcc ctcttccagc cgcttgatga cgagcacggc
    32701 aggcaacccg aaggtgccgc cgggaaactc cctcacccgc gtgccactca ccgcgacaca
    32761 ccagtccggg acataccccc gagcgatctc ctcaccgctc tccacatcga tgacaggcgt
    32821 ggaagccgac aggttggtgc cggcgccgac gacggtcccg cgccccaccc gggccccctc
    32881 ggtgatcatc gaccggctgc cgatcatcgc gtcgtcctcg atcacgaccg gccgcgcgtt
    32941 cggcggctcc agcaccccgc cgatccccac gccgcccgac aggtgcacgt tccggccgat
    33001 ctgggcgcac gacccgaccg tggcccaggt gtcgaccatc gtgcccgcgt ccacgtacgc
    33061 gccgatgttc acgaacgacg gcatcagcac caccccgggc gccaggtagg cgccccagcg
    33121 ggcgatggcg ccgggcacca cgcgcacgcc ctccagccgc gacttcagcg ggatgcggtc
    33181 gtggtactgg aagtccccga cctgcgagcg caccatgccg aggaccttga agctgagcag
    33241 gatggcgcgc ttgacccgtt cgtccaccac gacctgaccg ctgcccgggt ccacgaacgc
    33301 cgcgcgggcc tccccggcgt cgatctggtc gaccgccgcg acgatcgccg cccgcgcgcc
    33361 cgcgtcgtcg ggcgacagct cggcgcgccg ctcccacagc tcgtcgacga cccccgaaag
    33421 cgggctggtg aacgtttggg tcatggccct tgagcttagt ggggccatct cccggtacgg
    33481 tcgtcgcgtg gctgcaacgg cgaaggacaa gcgaggtgcg cggcggtggc gctggaccgc
    33541 cgtcacgctg gtcaccgtgc tcgttctggg gaccggcggt tacctcctgt tccgccaggt
    33601 ccgcccctat ctgcacggct cgggctgcga ggtgcggacc cccgccggga agatgccgct
    33661 ggacctggag caggccgcca acgcgagcac gatcgcggcg gtggccttcc gcaagcagct
    33721 ccccgaacgc gccgccgtga tcgcctacgc gaccgcgatc caggagtccc acatccggaa
    33781 cctggccgac ggcgaccgcg actcggtggg catgttccag cagcgcccgt cccagggctg
    33841 gggcagcccc gacaagctgc gcgacccggt cacctccacc agcaagttct tcgacgccct
    33901 gaccaaggtg aaggactacc tggaccgcga cctgcacgac gcggcccagc gcgtgcagcg
    33961 cagcgccgac ggcgacgcct acgcccagca cgaaccggac ggcaaactgc tggcgaaggc
    34021 gttcacgggc cgcgaaccgg cgagcgtgcg ctgctggttc ccgccggaca agaagacgaa
    34081 gccgcgccgc cccgaggcga tccgcgaact gcgccgagcc ttcggcagcc gcctccagct
    34141 ggacaccccg caaacagtgt cgagcccgcc cccaccccgg ccaacggacg cgatccgggt
    34201 ctccagctcc cgcacgggct gggcggtggc ctcgtgggcg acgacgcacg cgcaggtgta
    34261 cggcctgacg gaggtacgcc acaacggccg ccgctggagc gccgaaaacg gccacgacgg
    34321 ctggctgaaa gaccccgaag cccccaccga ccgcgtcatc ctccgctagc cggaccacaa
    34381 ccggccgccc tttctccacc gttccgagaa cggcgacctt gacaattccg cagaaccaca
    34441 ttccccacct ccaagaggaa acgggaaacg ccggaaccgt cttgtaaccc cccggagcct
    34501 gacgcacgct tacagacgag aagctcttgc ggagctgtgt ccgcgtacat ggattcgccc
    34561 gatcgtcctg cccgtcacgc agaagttccc gaacgacgat ccgctctact tccgactaca
    34621 aagaaggaaa tagcaccacc gaagccggcc cggccacaaa gcagcactgc accccgaagg
    34681 cataaccatc acgccgagga gtgaagaatg cacggcaacg ccgaggcgtg gccacgagga
    34741 ccgttcggcc cgtccggggc cgtgggttcg accgtgcgcg cacgccgcac cgtcttggcc
    34801 gtcacccacc atgtcaccgc cgccacgcgc ctggccgacg tcatgcccct tctggagagc
    34861 gatccgcgca tcgcggtcgc ctacacccgc gcgcccgcct cggccttcac cggcggactc
    34921 gacgagatgc tgcaccggat gggcgggctg gtactgccct ggcagcaggc tgtgcagacg
    34981 cccttcgacc tctgtgtcgc agcgagccac gggatgctgg agcagttgca cgcgccggtg
    35041 ctgacgatcc cgcacggcgc gggtccgggc aagctgctgc accgtgcgcc gggattcggc
    35101 ccggccgccg accgtccggt gacggggctg ctgcggcacc gggtggtggt ggacggacgg
    35161 gtcgtgcctt cggcgatggc gttcgggcac gaacgacacc tgcggcaggt cgaggccgag
    35221 tgccccgagg cgctgccggt cgccttcgtc tgcggcgatc cctgcctgga ccggctgatc
    35281 gccagcctgc cgtaccagac ggcctatcgc cgggcgctcg gcaccggaga cggacgacga
    35341 gtcgtcctca tcagttccac ctggggcgcg cactccctgc tggggcaacg ctctgacctg
    35401 ttgcaacgcg tcgtcgatga actgtcaccc gaccaatacc aggtcgtcgt ggccctgcac
    35461 ccgcacatct gggcctggca cggccgccgc cagatcatcg cctggtgcgc cgacgggctg
    35521 cggttgctgc cccctgagga aggctggcag gccgcactgg tggctgcgga ccacgtcatc
    35581 ggcgatcacg gatcggtgac ctgctacggc gcggcgctcg gtgttccggt gctgctcggt
    35641 gcgttctccg agaccgaggt gtcacccggt tcacacgtcg cacggctcgg cgcgatcgca
    35701 ccgcgcgtgg attgggaaca gccgctcggt ccgcaactcg acgactcgct ccacgctttc
    35761 gacgaacgcg cctgcaccgc gttccgcgac gagctcagct cgcggcccga cgagtcggcg
    35821 cggttgttgc gtaaggagat gtaccggctg ttgcggctgg acgagcccga ccgccctccc
    35881 ctcgtcgagc cggtgtcctt gcctcaggcg gtgaatccgc ctgcggatcg gctcttgccg
    35941 gatcgcatgt tcggccacca gctcggagac tgcgcccaga agcacggtca cgccgaaccg
    36001 cccgacgagc cggagcgccg cctcgacagg cccgaagatc ccgaagctcc ggcggatccc
    36061 gtcccgggcg gtgaggacga gactccggcc agcgcggaag caggccgggg ccgcgctgat
    36121 tcccgcggaa gcccggcaag tgtccgacgc cgttgagagc atggtcgggt gcccttccta
    36181 ggaaagatca ctcttgccgg accccgaccg gacgcggacg agacgaccgc catgatggac
    36241 gccctggccg ccgccgtgga ggagggctgg agttcgccgc tgcccctcct gcccgcagcc
    36301 gaggacgagc acgagggcac cggcggaacg gtgctggact accgcgtcct cggttatccc
    36361 ggcggcggga tggtcctcgt cgtgctggac ggcgaggaca tccggtacga gcaggccgcg
    36421 ctggccaccg cggcgctcgg cgggcactgc acgagctgga gccccgggct gatggagtac
    36481 accgtgacgg aggtgctgat cacgccgctc gacgagccgc acgacgccga gaactggctg
    36541 ccccctttcg cggacgagga ggagcccacg gtgcggtggc cgttggagca cctgatcggc
    36601 gacgatctgc agtccctggc cgcccggtac ctgctgctcg cgggtgtgcg gtcgctctgg
    36661 aacgtaccca ggcggtccga ccggccgcgg atcgacgccg acgacgtggc catcggcgcg
    36721 gccgatcacg cttggagccc cgaactggcg ggagagctcg gcacgctgct gatccaggcg
    36781 gcacggctgg aacgggagct gtcctccgaa cccggaccgg tcgtcctcgg agaagccgac
    36841 gcggaactga cggccgatct cctccagctc gtgagagcga cagctgtaca gcacgagaca
    36901 gagggctgga ccgaggacca tatgcggggt cacgccctcc ttgagcgctt catggaggac
    36961 catgcgctgc tatggaaccg cgtcctcgac gatgatccgg aaggccgtca tgaccagctc
    37021 agcgccaggc ggctgcggaa cctgcttcgc gcgggcatgt ctgccctcgc cacgctcctg
    37081 gtggtctagg tgtcgttgta
//
