BGC0000261 - 1 region(s) - antiSMASH results

BGC0000261 (Streptomyces sp. R1128)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T2PKS	1	17,200	rubrolone A / rubrolone B	Alkaloid	25%

BGC0000261 - Region 1 - T2PKS

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Location: 1 - 17,200 nt. (total: 17,200 nt) Show pHMM detection rules used

Region on contig edge.

T2PKS: (t2ks and t2clf)

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

External annotation

Name		MIBiG
Version		3.0

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000261.1	1.00	Polyketide	R1128	Streptomyces sp. R1128
BGC0000248.1	0.27	Polyketide	naphtocyclinone	Streptomyces arenae
BGC0001903.1	0.25	Other	neocarazostatin A	Streptomyces sp. MA37
BGC0001197.1	0.22	Polyketide	frankiamicin	Frankia sp. EAN1pec
BGC0000286.1	0.22	Polyketide	viguiepinol	Streptomyces sp. KO-3988
BGC0000228.1	0.22	Polyketide	granaticin	Streptomyces violaceoruber
BGC0000231.1	0.21	Polyketide	griseusin	Streptomyces griseus
BGC0002008.1	0.21	Other	aryl polyenes	Xenorhabdus doucetiae
BGC0001991.1	0.21	Polyketide	toblerol A, toblerol B, toblerol C, toblerol D, toblerol E, toblerol F, toblerol G, toblerol H	Methylorubrum extorquens AM1
BGC0000215.1	0.21	Polyketide	curamycin	Streptomyces cyaneus

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000261.1	1.00	Polyketide	R1128	Streptomyces sp. R1128
BGC0000248.1	0.60	Polyketide	naphtocyclinone	Streptomyces arenae
BGC0001903.1	0.58	Other	neocarazostatin A	Streptomyces sp. MA37
BGC0001197.1	0.55	Polyketide	frankiamicin	Frankia sp. EAN1pec
BGC0000286.1	0.55	Polyketide	viguiepinol	Streptomyces sp. KO-3988
BGC0000228.1	0.54	Polyketide	granaticin	Streptomyces violaceoruber
BGC0000231.1	0.54	Polyketide	griseusin	Streptomyces griseus
BGC0002008.1	0.54	Other	aryl polyenes	Xenorhabdus doucetiae
BGC0001991.1	0.53	Polyketide	toblerol A, toblerol B, toblerol C, toblerol D, toblerol E, toblerol F, toblerol G, toblerol H	Methylorubrum extorquens AM1
BGC0000215.1	0.53	Polyketide	curamycin	Streptomyces cyaneus

Similar known gene clusters

Type II PKS

Type II PKS gene cluster prediction details

Cluster section:: 0 to 17200
Starter unit(s):: acetyl-CoA (Score: 335.5; E-value: 0)
propionyl-CoA (Score: 335.5; E-value: 0)
isobutyryl-CoA (Score: 335.5; E-value: 0)
butyryl-CoA (Score: 335.5; E-value: 0)
Malonyl elongations:: 7 (Score: 747.1; E-value: 9.5e-228)
Product molecular weight(s):: acetyl-CoA_7: 321.30 Da
butyryl-CoA_7: 349.36 Da
isobutyryl-CoA_7: 349.36 Da
propionyl-CoA_7: 335.33 Da

zhuA: CLF 7 (Score: 747.1; E-value: 9.5e-228)
zhuB: KS (Score: 759.4; E-value: 2.1e-231)
zhuC: AT (Score: 415.9; E-value: 2.7e-127); AT AAG30190.1_R1128_acetyl-CoA/propionyl-CoA/isobutyryl-CoA/butyryl-CoA (Score: 674.0; E-value: 0.0)
zhuG: ACP (Score: 88.5; E-value: 5.1e-28)
zhuH: KSIII (Score: 413.3; E-value: 1.8e-126); KSIII AAG30195.1_R1128_acetyl-CoA/propionyl-CoA/isobutyryl-CoA/butyryl-CoA (Score: 668.0; E-value: 0.0)
zhuI: CYC C7-C12 (Score: 129.7; E-value: 2.4e-40)
zhuJ: CYC C5-C14/C3-C16 (Score: 340.2; E-value: 1.7e-104)
zhuK: OXY (Score: 508.4; E-value: 4.9e-155)
zhuM: OXY (Score: 488.4; E-value: 5.6e-149)
zhuN: ACP (Score: 123.2; E-value: 7.8e-39)