MIBiG Protein Description MIBiG Cluster MiBiG Product % ID % Coverage BLAST Score E-value
AAK57522.1 PgaE BGC0000262 Polyketide:Type II + Saccharide:Hybrid/tailoring 100.0 100.0 987.0 1.1e-287
QDG00828.1 FAD-binding_protein BGC0002028 Polyketide 82.0 100.0 819.0 3.9e-237
AAX57188.2 auricin_polyketide_oxiygenase BGC0000201 Polyketide:Type II + Saccharide:Hybrid/tailoring 80.0 99.0 781.0 9e-226
CAH10119.1 putative_oxygenase BGC0000268 Polyketide 77.0 99.2 748.0 6.5e-216
ADI71441.1 putative_oxygenase BGC0000203 Polyketide 74.0 99.0 734.0 9.7e-212
AGO50609.1 oxidoreductase BGC0000229 Polyketide:Type II + Saccharide:Hybrid/tailoring 75.0 99.4 733.0 2.8e-211
BAV16997.1 putative_oxygenase BGC0001384 Polyketide 76.0 99.4 731.0 8.2e-211
AAD13534.1 oxygenase_homolog BGC0000239 Polyketide:Type II + Saccharide:Hybrid/tailoring 76.0 100.0 731.0 1.1e-210
ARO44651.1 monooxygenase BGC0001769 Polyketide 74.0 99.4 716.0 3.6e-206
EHM27503.1 monooxygenase_FAD-binding BGC0000235 Polyketide 70.0 99.2 693.0 2.5e-199
ACP19351.1 SaqE BGC0000267 Polyketide:Type II + Saccharide:Oligosaccharide 71.0 99.6 688.0 6.1e-198
OWA25247.1 monooxygenase BGC0001438 Polyketide + Saccharide:Hybrid/tailoring 70.0 99.0 681.0 9.7e-196
AAK06782.1 putative_oxygenase_SimA7 BGC0001072 Saccharide + Polyketide:Modular type I + Polyketide:Type II + Other:Aminocoumarin 69.0 99.6 673.0 3.4e-193
PPQ57487.1 monooxygenase BGC0002016 Polyketide 68.0 99.0 665.0 9.4e-191
ARK36153.1 oxygenase BGC0001723 Polyketide 67.0 99.2 658.0 6.7e-189
CAG14963.1 oxygenase BGC0000253 Polyketide:Type II 66.0 99.2 639.0 3.2e-183
ADB02842.1 AzicO4 BGC0000202 Polyketide 65.0 99.2 630.0 2.6e-180
BAJ07857.1 putative_oxygenase BGC0000232 Polyketide 67.0 93.5 621.0 1.6e-177
ADB02837.1 AzicO3 BGC0000202 Polyketide 62.0 99.0 618.0 7.7e-177
ALJ99849.1 FlsO2 BGC0001904 Polyketide 61.0 99.6 583.0 2.8e-166
AAO65352.1 oxygenase-like_protein BGC0000236 Polyketide 60.0 100.4 581.0 1.4e-165
CBH32814.1 putative_monooxygenase BGC0000263 Polyketide 59.0 99.2 573.0 2.8e-163
CBH32083.1 putative_FAD-dependent_monooxygenase BGC0000211 Polyketide 60.0 99.2 570.0 2.4e-162
AEE65462.1 oxygenase BGC0000223 Polyketide:Type II 59.0 98.6 557.0 1.6e-158
ARD70872.1 FAD-binding_monooxygenase BGC0001693 Polyketide 60.0 99.6 555.0 8e-158
ARD70875.1 FAD-binding_monooxygenase BGC0001693 Polyketide 57.0 100.0 547.0 2.2e-155
WP_040253455.1 monooxygenase BGC0001596 Polyketide 57.0 101.0 538.0 1e-152
ABP54650.1 monooxygenase,_FAD-binding BGC0000241 Polyketide:Type II + Saccharide:Hybrid/tailoring 56.0 100.2 528.0 1.1e-149
ALJ99859.1 FlsO1 BGC0001904 Polyketide 55.0 100.0 524.0 1.5e-148
ABP54647.1 monooxygenase,_FAD-binding BGC0000241 Polyketide:Type II + Saccharide:Hybrid/tailoring 57.0 99.6 524.0 2.6e-148
AHZ61858.1 FAD-binding_monooxygenase BGC0000240 Polyketide:Type II + Saccharide:Hybrid/tailoring 57.0 99.6 523.0 3.4e-148
ALJ99869.1 FlsO5 BGC0001904 Polyketide 54.0 100.2 518.0 1.1e-146
AVO00807.1 May8 BGC0001661 Polyketide 55.0 100.6 516.0 4.1e-146
AEE65473.1 oxygenase-like_protein BGC0000223 Polyketide:Type II 54.0 100.2 512.0 7.8e-145
AHZ61861.1 FAD-binding_monooxygenase BGC0000240 Polyketide:Type II + Saccharide:Hybrid/tailoring 55.0 100.2 510.0 2.3e-144
AEE65484.1 monooxygenase BGC0000223 Polyketide:Type II 53.0 99.4 496.0 4.4e-140
AAO65343.1 oxygenase-like_protein BGC0000236 Polyketide 54.0 99.6 493.0 2.9e-139
ALJ99864.1 FlsO4 BGC0001904 Polyketide 52.0 100.4 482.0 1.1e-135
WP_040253436.1 monooxygenase BGC0001596 Polyketide 51.0 99.4 478.0 1.6e-134
ACP19358.1 SaqM BGC0000267 Polyketide:Type II + Saccharide:Oligosaccharide 51.0 100.0 465.0 8.4e-131
AAO65351.1 oxygenase_reductase-like_protein BGC0000236 Polyketide 50.0 100.0 462.0 1.2e-129
AAD13541.1 Dehydratase BGC0000239 Polyketide:Type II + Saccharide:Hybrid/tailoring 49.0 100.0 453.0 4.3e-127
AAX57196.2 auricin_polyketide_oxygenase-reductase BGC0000201 Polyketide:Type II + Saccharide:Hybrid/tailoring 49.0 101.6 448.0 1.8e-125
CAG14970.1 oxygenase BGC0000253 Polyketide:Type II 48.0 102.0 447.0 3.1e-125
AHZ61850.1 FAD-binding_monooxygenase BGC0000240 Polyketide:Type II + Saccharide:Hybrid/tailoring 50.0 100.0 446.0 6.9e-125
ABP54639.1 monooxygenase,_FAD-binding BGC0000241 Polyketide:Type II + Saccharide:Hybrid/tailoring 49.0 100.6 445.0 9e-125
ARK36160.1 oxidoreductase BGC0001723 Polyketide 48.0 102.0 445.0 1.5e-124
AAL15585.1 Sim7 BGC0000270 Polyketide 49.0 99.8 441.0 1.7e-123
AEE65478.1 putative_oxygenase BGC0000223 Polyketide:Type II 49.0 100.2 441.0 2.2e-123
AAK57530.1 PgaM BGC0000262 Polyketide:Type II + Saccharide:Hybrid/tailoring 51.0 101.4 438.0 1.1e-122
ARD70864.1 FAD-binding_monooxygenase BGC0001693 Polyketide 50.0 101.0 437.0 2.4e-122
QDG00821.1 oxygenase-reductase BGC0002028 Polyketide 49.0 100.8 437.0 2.4e-122
ALJ99850.1 FlsO3 BGC0001904 Polyketide 48.0 100.0 431.0 2.3e-120
ABP54640.1 monooxygenase,_FAD-binding BGC0000241 Polyketide:Type II + Saccharide:Hybrid/tailoring 47.0 100.6 420.0 3.1e-117
AEE65463.1 Oxygenase_reductase-like_protein BGC0000223 Polyketide:Type II 48.0 99.2 420.0 4e-117
AHZ61851.1 FAD-binding_monooxygenase BGC0000240 Polyketide:Type II + Saccharide:Hybrid/tailoring 47.0 100.8 420.0 5.3e-117
CBH32087.1 putative_FAD-dependent_monooxygenase BGC0000211 Polyketide 47.0 99.0 410.0 5.4e-114
WP_040253452.1 oxidoreductase BGC0001596 Polyketide 47.0 96.1 404.0 1.8e-112
AAK06789.1 putative_oxygenase_SimA8 BGC0001072 Saccharide + Polyketide:Modular type I + Polyketide:Type II + Other:Aminocoumarin 46.0 101.4 403.0 6.7e-112
AVO00810.1 May11 BGC0001661 Polyketide 45.0 101.0 398.0 1.3e-110
AAG30198.1 oxygenase BGC0000261 Polyketide 44.0 101.8 398.0 1.6e-110
B9W61_07270 monooxygenase BGC0001438 Polyketide + Saccharide:Hybrid/tailoring 47.0 98.8 397.0 2.8e-110
AGZ15446.1 putative_polyketide_oxygenase/hydroxylase BGC0001036 NRP + Polyketide 47.0 102.0 395.0 1.4e-109
ARD70865.1 FAD-binding_monooxygenase BGC0001693 Polyketide 46.0 99.0 387.0 3.8e-107
ADB02848.1 AzicO5 BGC0000202 Polyketide 46.0 100.2 378.0 2.3e-104
AAZ78342.1 OxyS BGC0000254 Polyketide 44.0 101.6 367.0 4e-101
AAP69582.1 putative_FAD-dependent_oxygenase BGC0000226 Polyketide 43.0 99.0 366.0 5.3e-101
CBH32810.1 putative_oxygenase BGC0000263 Polyketide 43.0 105.5 363.0 7.6e-100
AKD43495.1 Monooxygenase BGC0001409 Polyketide 43.0 103.7 358.0 1.4e-98
ACN64854.1 PokO4 BGC0001061 Polyketide:Iterative type I + Polyketide:Type II + Saccharide:Hybrid/tailoring 42.0 103.7 353.0 6e-97
ACY06308.1 FAD-dependent_monooxygenase BGC0001042 NRP + Polyketide 46.0 103.5 352.0 1e-96
CAE17536.1 oxygenase BGC0000210 Polyketide:Type II + Saccharide:Oligosaccharide 43.0 104.1 350.0 3.9e-96
CAK50794.2 oxygenase BGC0000247 Polyketide:Type II + Saccharide:Oligosaccharide 44.0 102.2 348.0 1.5e-95
AAM97364.1 RubN BGC0000266 Polyketide 42.0 102.6 344.0 2.2e-94
AAZ77700.1 ChlE3 BGC0000036 Polyketide:Modular type I + Polyketide:Iterative type I + Saccharide:Oligosaccharide 41.0 101.8 341.0 3.1e-93
AFU65887.1 DacO3 BGC0000216 Polyketide 42.0 97.4 339.0 6.9e-93
BAV17004.1 putative_oxygenase-reductase BGC0001384 Polyketide 43.0 100.6 334.0 2.9e-91
BAJ07846.1 putative_oxygenase-reductase BGC0000232 Polyketide 41.0 103.1 333.0 5e-91
AAM33673.1 putative_FAD-dependent_monooxygenase_GrhO6 BGC0000230 Polyketide:Type II 40.0 101.2 332.0 8.5e-91
AAZ77692.1 ChlE1 BGC0000036 Polyketide:Modular type I + Polyketide:Iterative type I + Saccharide:Oligosaccharide 39.0 105.5 332.0 1.1e-90
BAQ25484.1 FAD-dependent_oxidoreductase BGC0001288 Polyketide 41.0 102.2 331.0 1.9e-90
ARD70874.1 FAD-binding_monooxygenase BGC0001693 Polyketide 43.0 94.7 329.0 1.2e-89
ARO44645.1 monooxygenase BGC0001769 Polyketide 42.0 101.2 328.0 1.6e-89
ADI71448.1 putative_oxygenase-reductase BGC0000203 Polyketide 40.0 100.2 324.0 3e-88
AHZ61860.1 FAD-binding_monooxygenase BGC0000240 Polyketide:Type II + Saccharide:Hybrid/tailoring 41.0 97.6 320.0 5.7e-87
AEI98657.1 CtcN BGC0000209 Polyketide 42.0 102.2 318.0 1.7e-86
AFU65892.1 DacO1 BGC0000216 Polyketide 39.0 102.4 317.0 4.8e-86
AGO50615.1 oxygenase-reductase BGC0000229 Polyketide:Type II + Saccharide:Hybrid/tailoring 40.0 101.4 314.0 3.1e-85
ACB46484.1 FAD-dependent_oxidoreductase BGC0000082 Polyketide 39.0 100.8 312.0 9.1e-85
BAQ21949.1 putative_FAD-dependent_oxidoreductase BGC0001204 Polyketide 39.0 106.3 312.0 9.1e-85
ACR50781.1 putative_FAD-dependent_oxygenase BGC0000163 Polyketide 40.0 102.2 312.0 1.2e-84
EHM27510.1 monooxygenase_FAD-binding BGC0000235 Polyketide 45.0 77.4 311.0 2e-84
ABP54649.1 monooxygenase,_FAD-binding BGC0000241 Polyketide:Type II + Saccharide:Hybrid/tailoring 40.0 97.8 310.0 5.9e-84
AOZ61203.1 oxygenase BGC0001762 Alkaloid 40.0 106.3 310.0 5.9e-84
PPQ57494.1 monooxygenase BGC0002016 Polyketide 40.0 100.4 309.0 1e-83
ACB37744.1 FAD-dependent_oxygenase BGC0000162 Polyketide 37.0 101.0 294.0 3.3e-79
WP_020275087.1 FAD-dependent_oxidoreductase BGC0002012 Polyketide 40.0 104.5 293.0 5.7e-79
AGC09488.1 LobA BGC0001183 Polyketide 37.0 101.8 291.0 2.8e-78
AAO06914.1 GdmL BGC0000066 Polyketide 40.0 100.2 290.0 4.8e-78
AGI99493.1 FAD-dependent_oxidoreductase BGC0001004 Polyketide:Modular type I 37.0 101.8 290.0 6.3e-78
AAY28223.1 HbmL BGC0000074 Polyketide 40.0 99.4 289.0 1.1e-77
ARG41919.1 IstP BGC0001622 Polyketide 37.0 102.9 280.0 6.5e-75
BAE93724.1 putative_FAD-dependent_monooxygenase BGC0000164 Polyketide 36.0 104.1 275.0 1.6e-73
AAG30200.1 oxygenase BGC0000261 Polyketide 36.0 104.9 265.0 1.3e-70
ABI22123.1 monooxygenase BGC0000422 NRP 34.0 101.8 251.0 2.5e-66
AHB38501.1 FAD-dependent_oxidoreductase BGC0000346 NRP + Polyketide:Modular type I 37.0 106.7 248.0 2.1e-65
AGD80608.1 monooxygenase BGC0000394 NRP 35.0 100.2 245.0 1.4e-64
CAG14971.1 oxygenase BGC0000253 Polyketide:Type II 37.0 100.6 241.0 2.6e-63
ARK36161.1 hypothetical_protein BGC0001723 Polyketide 37.0 100.6 241.0 2.6e-63
AWS21287.1 monooxygenase BGC0001934 Polyketide 34.0 102.4 239.0 9.7e-63
AZY91999.1 spiro_cyclase BGC0002022 Polyketide 34.0 102.4 239.0 9.7e-63
ctg1_orf39 BGC0001013 NRP + Polyketide 38.0 99.8 238.0 1.7e-62
ABO15838.1 FAD-dependent_monooxygenase BGC0000130 Polyketide 36.0 102.0 235.0 2.4e-61
CAH10112.1 putative_oxidase-reducatse BGC0000268 Polyketide 38.0 72.1 219.0 1.4e-56
ABC87527.1 FAD-dependent_monooxygenase BGC0001011 NRP + Polyketide 36.0 94.7 213.0 5.7e-55
CCE31578.1 related_to_phenol_2-monooxygenase BGC0001886 Polyketide 33.0 101.2 211.0 2.8e-54
AGI62225.1 AbeX1-like_monooxygenase BGC0001335 Alkaloid 34.0 109.0 180.0 5.4e-45
AAZ78335.1 OxyL BGC0000254 Polyketide 32.0 103.5 176.0 1.3e-43
ABX71099.1 Lct16 BGC0000238 Polyketide 32.0 102.0 173.0 1.1e-42
AKD43496.1 Monooxygenase BGC0001409 Polyketide 32.0 107.1 172.0 1.9e-42
AEF32090.1 monooxygenase BGC0001333 Alkaloid 33.0 106.5 169.0 1.2e-41
OWA01622.1 oxygenase BGC0001439 Polyketide + Saccharide:Hybrid/tailoring 34.0 80.2 168.0 2.1e-41
AEI98648.1 CtcE BGC0000209 Polyketide 35.0 69.7 166.0 8e-41
ADE34483.1 ssfO2 BGC0000269 Polyketide:Type II + Saccharide:Hybrid/tailoring 30.0 104.9 166.0 8e-41
AAP69585.1 putative_FAD-dependent_oxygenase BGC0000226 Polyketide 32.0 76.6 166.0 1.4e-40
AKQ99277.1 pentachlorophenol_4-monooxygenase BGC0001484 Other 36.0 69.9 166.0 1.4e-40
AEO12714.1 flavin_monooxygenase BGC0001334 Alkaloid 31.0 107.5 165.0 1.8e-40
CAA07757.1 oxygenase BGC0000246 Polyketide 30.0 102.0 164.0 4e-40
CAK50777.1 oxygenase BGC0000247 Polyketide:Type II + Saccharide:Oligosaccharide 30.0 102.0 164.0 4e-40
CAE17550.1 oxygenase BGC0000210 Polyketide:Type II + Saccharide:Oligosaccharide 33.0 80.9 163.0 1.2e-39
AQW35055.1 bifunctional_monooxygenase-dehydratase BGC0001675 Polyketide 32.0 87.4 162.0 2e-39
ACN64853.1 PokO2 BGC0001061 Polyketide:Iterative type I + Polyketide:Type II + Saccharide:Hybrid/tailoring 31.0 107.1 161.0 3.4e-39
ARS01465.1 NcmL BGC0001702 NRP + Polyketide 30.0 100.8 158.0 3.7e-38
BAQ25478.1 monooxygenase BGC0001288 Polyketide 35.0 72.7 156.0 1.4e-37
ABB88524.1 Baeyer-Villiger_monooxygenase BGC0000050 Polyketide 31.0 97.8 153.0 1.2e-36
AFU65903.1 DacO2 BGC0000216 Polyketide 33.0 80.7 151.0 4.6e-36
ADQ55479.1 FAD-binding_monooxygenase BGC0000350 NRP:Beta-lactam 24.0 99.0 146.0 1.1e-34
BAJ52699.1 putative_FAD-binding_monooxygenase BGC0000222 Polyketide 30.0 102.0 145.0 2.5e-34
AKQ20687.1 monooxygenase BGC0001337 Alkaloid 32.0 74.3 144.0 5.6e-34
CAO98853.1 monooxygenase_AufJ BGC0000023 Polyketide:Modular type I 30.0 78.4 143.0 1.2e-33
AHX24715.1 FAD-binding_monooxygenase BGC0000200 Polyketide:Type II + Saccharide:Hybrid/tailoring 28.0 104.5 139.0 1.1e-32
CAP12596.1 TcmB2_oxygenase BGC0000219 Polyketide:Type II + Saccharide:Hybrid/tailoring 28.0 111.2 136.0 1.2e-31
ADE22302.1 putative_FAD-binding_monooxygenase BGC0000279 Polyketide 29.0 107.7 136.0 1.5e-31
AWM72926.1 FAD-dependent_oxidoreductase BGC0001719 Polyketide 28.0 109.2 135.0 2e-31
AAD32744.1 MmcT BGC0000915 Other:Aminocoumarin 28.0 112.0 133.0 7.5e-31
AAO06920.1 GdmM BGC0000066 Polyketide 32.0 70.1 133.0 1.3e-30
ABI93781.1 GdmM BGC0000068 Polyketide 32.0 69.2 131.0 4.9e-30
BAJ52694.1 putative_polyketide_hydroxylase BGC0000222 Polyketide 29.0 101.6 131.0 4.9e-30
AAM97362.1 RubL BGC0000266 Polyketide 29.0 108.4 130.0 8.3e-30
AAM97366.1 RubP BGC0000266 Polyketide 27.0 103.1 129.0 1.4e-29
AIE54194.1 Pau27 BGC0001731 Other 28.0 107.7 129.0 1.4e-29
AUI41038.1 FAD-dependent_monooxygenase BGC0001512 Polyketide 32.0 73.1 129.0 1.9e-29
CAI94716.1 putative_hydroxyphenylpropionate BGC0000141 Polyketide 29.0 102.2 128.0 3.2e-29
AIE54247.1 PauY27 BGC0001732 Other 28.0 107.7 128.0 3.2e-29
CQR60483.1 Rif-orf19_homologue._FDA_dependent-monooxygenase;_Naphthalene_ring_formation;_3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic_acid_hydroxylase BGC0001287 Polyketide 31.0 75.4 126.0 1.2e-28
AHL46732.1 FAD_dependent_monooxygenase BGC0001179 Polyketide:Type II 28.0 108.6 126.0 1.6e-28
ACF35449.1 mbcM BGC0000090 Polyketide 32.0 68.4 125.0 2.1e-28
AHE14649.1 FAD-binding_monooxygenase BGC0001336 Alkaloid 30.0 80.0 125.0 2.7e-28
RLV71184.1 2-polyprenyl-6-methoxyphenol_hydroxylase-like_oxidoreductase BGC0001846 NRP + Saccharide:Hybrid/tailoring 32.0 70.5 124.0 3.5e-28
BAF47693.1 monooxygenase BGC0000825 Alkaloid 27.0 108.4 123.0 7.8e-28
AAM33676.1 putative_FAD-dependent_oxidoreductase_GrhO9 BGC0000230 Polyketide:Type II 28.0 111.4 123.0 1.3e-27
AAA67511.1 hydroxylase BGC0000275 Polyketide:Type II 28.0 111.2 123.0 1.3e-27
ASA49574.1 hydroxylase BGC0001730 Polyketide 28.0 109.2 123.0 1.3e-27
AXO35174.1 hypothetical_protein BGC0001848 Other 29.0 109.4 122.0 1.7e-27
AFY23037.1 TamF BGC0000274 Polyketide:Type II 30.0 84.7 121.0 3.9e-27
ABV98191.1 monooxygenase_FAD-binding BGC0000827 Alkaloid 25.0 109.0 120.0 8.6e-27
EWM63062.1 FAD-binding_monooxygenase BGC0000679 Terpene 28.0 109.2 118.0 3.3e-26
BAB69162.1 hydroxylase BGC0000271 Polyketide 28.0 103.5 118.0 4.3e-26
AHE81001.1 PieE BGC0001169 Polyketide:Modular type I 27.0 110.4 114.0 3.6e-25
EFG04594.1 Staurosporine_biosynthesis_monooxygenase_StaC BGC0000826 Alkaloid 27.0 110.8 113.0 8.1e-25
WP_051422534.1 hypothetical_protein BGC0000198 Polyketide:Type II + Saccharide:Hybrid/tailoring 29.0 77.0 112.0 2.3e-24
AUW31182.1 putative_monooxygenase BGC0001489 Polyketide 28.0 82.3 112.0 2.3e-24
AHZ61847.1 FAD-binding_monooxygenase_aromatic_ring_hydroxylase BGC0000240 Polyketide:Type II + Saccharide:Hybrid/tailoring 29.0 75.2 111.0 5.2e-24
AEO12712.1 flavin_monooxygenase BGC0001334 Alkaloid 28.0 111.6 111.0 5.2e-24
AMX23348.1 putative_monooxygenase BGC0001500 Polyketide 26.0 106.5 110.0 8.9e-24
AFV30246.1 FAD-binding_monooxygenase BGC0000075 Polyketide 30.0 71.3 109.0 1.2e-23
AAM33675.1 putative_FAD-dependent_monooxygenase_GrhO8 BGC0000230 Polyketide:Type II 26.0 105.1 106.0 9.9e-23
ABP54636.1 monooxygenase,_FAD-binding BGC0000241 Polyketide:Type II + Saccharide:Hybrid/tailoring 29.0 74.9 106.0 1.7e-22
EAU38788.1 conserved_hypothetical_protein BGC0000161 Polyketide:Iterative type I 25.0 75.2 103.0 1.1e-21
ATY46592.1 monooxygenase_FAD-binding_protein BGC0001666 Polyketide 27.0 72.9 102.0 2.4e-21
ARD70861.1 FAD-binding_monooxygenase BGC0001693 Polyketide 27.0 92.1 97.0 4.6e-20
AJO72705.1 Monooxygenase BGC0001381 Polyketide 28.0 67.4 95.0 3e-19
AAG26878.1 PKSA_putative_hydroxylase BGC0000272 Polyketide 25.0 109.8 77.0 8.4e-14
AHD25942.1 ChdOII BGC0000208 Polyketide 35.0 33.8 75.0 2.4e-13