BGC0000262: prejadomycin biosynthetic gene cluster from Streptomyces sp. PGA64
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Location: 1 - 54,042 nt. (total: 54,042 nt).
This entry is originally from NCBI GenBank AY034378.2.

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core biosynthetic genes
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Gene details
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General
Compounds
Genes
Polyketide
Saccharide
History
NRPS/PKS domains
General information about the BGC
MIBiG accession BGC0000262
Short description prejadomycin biosynthetic gene cluster from Streptomyces sp. PGA64
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide (Angucycline)
  • Saccharide (hybrid/tailoring)
Loci NCBI GenBank: AY034378.2
Compounds
  • prejadomycin
  • Rabelomycin
  • gaudimycin C
  • gaudimycin D
  • UWM6
  • gaudimycin A
Species Streptomyces sp. PGA64 [taxonomy]
References
Chemical products information
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prejadomycin
Molecular Formula C28HO5
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Rabelomycin
Molecular Formula C31O6
Chemical database entries NPAtlas  
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gaudimycin C
Molecular Formula C67HO7
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gaudimycin D
Molecular Formula C72H3NO8
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UWM6
Molecular Formula C29HO6
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gaudimycin A
Molecular Formula C29O6
List of genes involved in compound(s) production
Identifiers Position Product Functions Extra
  • AAK57521.2
1 795 + putative nucleotide-binding protein
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  • AHW57761.1
884 1933 + putative polyprenyl synthetase
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  • AHW57762.1
2022 2618 + putative acetyltransferase
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  • AHW57763.1
2843 3343 + hypothetical protein
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  • AHW57764.1
3479 4027 - PgaR4
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  • AHW57765.1
4541 5191 - PgaR2
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  • AHW57766.1
5321 6112 - PgaR1
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  • AHW57767.1
6445 7500 + PgaW1
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  • AHW57768.1
7511 8449 + PgaW2
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  • AHW57769.1
8649 10421 + PgaN
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  • AHW57770.1
10714 11664 - PgaK
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  • AAK57522.1
12038 13513 + PgaE
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  • AAK57523.1
13648 14307 + PgaY
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  • AAK57524.1
14375 14704 + PgaY
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  • AAK57525.1
14742 16010 + PgaA
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  • AAK57526.1
16007 17224 + PgaB
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  • AAK57527.1
17325 17594 + PgaC
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  • AAK57528.1
17698 18483 + PgaD
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  • AAK57529.1
18560 19504 + PgaL
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  • AAK57530.1
19506 21860 + PgaM
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  • AAK57531.1
21981 23447 + PgaJ
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  • AAK57532.1
23818 24660 + PgaX
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  • AAK57533.1
24816 25769 + PgaH
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  • AAK57534.1
25798 27363 + PgaI
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  • AHW57771.1
27411 27644 + Pga11
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  • AHW57772.1
27907 28422 + Pga10
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  • AHW57773.1
28464 29375 + Pga1
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  • AHW57774.1
29396 30316 + Pga2
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  • AHW57775.1
30394 31917 + PgaJ2
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  • AHW57776.1
32100 33251 + PgaC1
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  • AHW57777.1
33276 33857 + PgaZ1
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  • AHW57778.1
33887 35167 + PgaG3
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  • AHW57779.1
35167 36153 + PgaZ3
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  • AHW57780.1
36144 37391 + PgaG1
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  • AHW57781.1
37375 38154 + PgaR
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  • AHW57782.1
38154 39308 + PgaG2
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  • AHW57794.1
39391 40620 + PgaG6
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  • AHW57783.1
40676 42037 + PgaG4
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  • AHW57784.1
42114 42707 + PgaO
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  • AHW57785.1
42936 43388 - PgaR3
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  • AHW57786.1
43541 44608 + PgaG
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  • AHW57787.1
44605 45594 + PgaH1
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  • AHW57788.1
45598 46902 + PgaQ
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  • AHW57789.1
46899 48293 + PgaS
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  • AHW57790.1
48290 49252 + PgaT
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  • AHW57791.1
49323 50585 + Pga5
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  • AHW57792.1
50630 52213 + PgaJ3
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  • AHW57793.1
52308 52934 + putative oxidoreductase
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Polyketide-specific information
Subclass Angucycline
Starter unit Acetyl-CoA
Ketide length 10
Cyclic? yes
Polyketide-synthases
Genes Properties Modules
AAK57528.1
+
AAK57524.1
+
AAK57525.1
+
AAK57529.1
Synthase subclass: Type II
Saccharide-specific information
Subclass hybrid/tailoring
Glycosyltransferases
>AHW57778.1
Specificity: Unknown
Evidence:
  • Sequence-based prediction
>AHW57780.1
Specificity: Unknown
Evidence:
  • Sequence-based prediction
>AHW57782.1
Specificity: Unknown
Evidence:
  • Sequence-based prediction
>AHW57794.1
Specificity: Unknown
Evidence:
  • Sequence-based prediction
>AHW57783.1
Specificity: Unknown
Evidence:
  • Sequence-based prediction
>AHW57791.1
Specificity: Unknown
Evidence:
  • Sequence-based prediction
Annotation changelog
MIBiG version Notes
2.0
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
Detailed domain annotation
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