BGC0000262: prejadomycin biosynthetic gene cluster from Streptomyces sp. PGA64
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Location: 1 - 54,042 nt. (total: 54,042 nt).
This entry is originally from NCBI GenBank AY034378.2.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
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resistance
TTA codons
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Gene details
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General
Compounds
Genes
Polyketide
Saccharide
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000262
Short description prejadomycin biosynthetic gene cluster from Streptomyces sp. PGA64
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide (Angucycline)
  • Saccharide (hybrid/tailoring)
Loci NCBI GenBank: AY034378.2
Compounds
  • prejadomycin
  • rabelomycin
  • gaudimycin C
  • gaudimycin D
  • UWM6
  • gaudimycin A
Species Streptomyces sp. PGA64 [taxonomy]
References
Chemical products information
prejadomycin
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C19H16O5
rabelomycin
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C19H14O6
Chemical database entries
NPAtlas
gaudimycin C
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C19H16O7
gaudimycin D
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C25H27N1O8
UWM6
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C19H18O6
gaudimycin A
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C19H16O6
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AAK57521.2
 1 - 795 (+) putative nucleotide-binding protein
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  • AHW57761.1
 884 - 1933 (+) putative polyprenyl synthetase
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  • AHW57762.1
 2022 - 2618 (+) putative acetyltransferase
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  • AHW57763.1
 2843 - 3343 (+) hypothetical protein
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  • AHW57764.1
 3479 - 4027 (-) PgaR4
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  • AHW57765.1
 4541 - 5191 (-) PgaR2
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  • AHW57766.1
 5321 - 6112 (-) PgaR1
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  • AHW57767.1
 6445 - 7500 (+) PgaW1
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  • AHW57768.1
 7511 - 8449 (+) PgaW2
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  • AHW57769.1
 8649 - 10421 (+) PgaN
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  • AHW57770.1
 10714 - 11664 (-) PgaK
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  • AAK57522.1
 12038 - 13513 (+) PgaE
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  • AAK57523.1
 13648 - 14307 (+) PgaY
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  • AAK57524.1
 14375 - 14704 (+) PgaY
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  • AAK57525.1
 14742 - 16010 (+) PgaA
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  • AAK57526.1
 16007 - 17224 (+) PgaB
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  • AAK57527.1
 17325 - 17594 (+) PgaC
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  • AAK57528.1
 17698 - 18483 (+) PgaD
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  • AAK57529.1
 18560 - 19504 (+) PgaL
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  • AAK57530.1
 19506 - 21860 (+) PgaM
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  • AAK57531.1
 21981 - 23447 (+) PgaJ
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  • AAK57532.1
 23818 - 24660 (+) PgaX
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  • AAK57533.1
 24816 - 25769 (+) PgaH
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  • AAK57534.1
 25798 - 27363 (+) PgaI
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  • AHW57771.1
 27411 - 27644 (+) Pga11
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  • AHW57772.1
 27907 - 28422 (+) Pga10
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  • AHW57773.1
 28464 - 29375 (+) Pga1
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  • AHW57774.1
 29396 - 30316 (+) Pga2
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  • AHW57775.1
 30394 - 31917 (+) PgaJ2
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  • AHW57776.1
 32100 - 33251 (+) PgaC1
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  • AHW57777.1
 33276 - 33857 (+) PgaZ1
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  • AHW57778.1
 33887 - 35167 (+) PgaG3
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  • AHW57779.1
 35167 - 36153 (+) PgaZ3
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  • AHW57780.1
 36144 - 37391 (+) PgaG1
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  • AHW57781.1
 37375 - 38154 (+) PgaR
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  • AHW57782.1
 38154 - 39308 (+) PgaG2
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  • AHW57794.1
 39391 - 40620 (+) PgaG6
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  • AHW57783.1
 40676 - 42037 (+) PgaG4
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  • AHW57784.1
 42114 - 42707 (+) PgaO
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  • AHW57785.1
 42936 - 43388 (-) PgaR3
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  • AHW57786.1
 43541 - 44608 (+) PgaG
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  • AHW57787.1
 44605 - 45594 (+) PgaH1
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  • AHW57788.1
 45598 - 46902 (+) PgaQ
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  • AHW57789.1
 46899 - 48293 (+) PgaS
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  • AHW57790.1
 48290 - 49252 (+) PgaT
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  • AHW57791.1
 49323 - 50585 (+) Pga5
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  • AHW57792.1
 50630 - 52213 (+) PgaJ3
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  • AHW57793.1
 52308 - 52934 (+) putative oxidoreductase
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Polyketide-specific information
Subclass Angucycline
Starter unit Acetyl-CoA
Ketide length 10
Cyclic? yes
Polyketide-synthases
Genes Properties Modules
AAK57528.1
+
AAK57524.1
+
AAK57525.1
+
AAK57529.1 		Synthase subclass: Type II
Saccharide-specific information
Subclass hybrid/tailoring
Glycosyltransferases
AHW57778.1
Evidence:
  • Sequence-based prediction
AHW57780.1
Evidence:
  • Sequence-based prediction
AHW57782.1
Evidence:
  • Sequence-based prediction
AHW57794.1
Evidence:
  • Sequence-based prediction
AHW57783.1
Evidence:
  • Sequence-based prediction
AHW57791.1
Evidence:
  • Sequence-based prediction
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: HSOJFFPY5IUT4HBQLSN7DGJX, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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