BGC0000267: saquayamycin Z biosynthetic gene cluster from Micromonospora sp. Tu 6368
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Location: 1 - 36,648 nt. (total: 36,648 nt).
This entry is originally from NCBI GenBank FJ670504.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
Polyketide
Saccharide
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000267
Short description saquayamycin Z biosynthetic gene cluster from Micromonospora sp. Tu 6368
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide (Angucycline)
  • Saccharide (oligosaccharide)
Loci NCBI GenBank: FJ670504.1
Compounds
  • saquayamycin Z
Species Micromonospora sp. Tu 6368 [taxonomy]
References
Chemical products information
saquayamycin Z
Copy SMILES
C72H102O29
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ACP19348.1
1 - 427 (-) hypothetical protein
copy AA seq
copy Nt seq
  • ACP19349.1
  • saqI
1126 - 2274 (+) SaqI
copy AA seq
copy Nt seq
  • ACP19350.1
  • saqP
2459 - 3358 (+) SaqP
copy AA seq
copy Nt seq
  • ACP19351.1
  • saqE
3624 - 5096 (+) SaqE
copy AA seq
copy Nt seq
  • ACP19352.1
  • saqF
5125 - 5454 (+) SaqF
copy AA seq
copy Nt seq
  • ACP19353.1
  • saqA
5451 - 6719 (+) SaqA
copy AA seq
copy Nt seq
  • ACP19354.1
  • saqB
6716 - 7939 (+) SaqB
copy AA seq
copy Nt seq
  • ACP19355.1
  • saqC
7964 - 8236 (+) SaqC
copy AA seq
copy Nt seq
  • ACP19356.1
  • saqD
8275 - 9039 (+) SaqD
copy AA seq
copy Nt seq
  • ACP19357.1
  • saqL
9085 - 10029 (+) SaqL
copy AA seq
copy Nt seq
  • ACP19358.1
  • saqM
10094 - 11569 (+) SaqM
copy AA seq
copy Nt seq
  • ACP19359.1
  • saqN
11610 - 12371 (+) SaqN
copy AA seq
copy Nt seq
  • ACP19360.1
  • saqO
12476 - 13060 (+) SaqO
copy AA seq
copy Nt seq
  • ACP19361.1
  • saqGT1
13105 - 14379 (+) SaqGT1
copy AA seq
copy Nt seq
  • ACP19362.1
  • saqJ
14376 - 15785 (+) SaqJ
copy AA seq
copy Nt seq
  • ACP19363.1
  • saqGT2
15805 - 17136 (+) SaqGT2
copy AA seq
copy Nt seq
  • ACP19364.1
  • saqGT3
17121 - 18335 (+) SaqGT3
copy AA seq
copy Nt seq
  • ACP19365.1
  • saqGT4
18335 - 19525 (+) SaqGT4
copy AA seq
copy Nt seq
  • ACP19366.1
  • saqZ1
19528 - 20127 (+) SaqZ1
copy AA seq
copy Nt seq
  • ACP19367.1
  • saqR1
20114 - 20602 (-) SaqR1
copy AA seq
copy Nt seq
  • ACP19368.1
  • saqK
20595 - 21218 (-) SaqK
copy AA seq
copy Nt seq
  • ACP19369.1
  • saqJ1
21355 - 22911 (+) SaqJ1
copy AA seq
copy Nt seq
  • ACP19370.1
  • saqGT5
23224 - 24375 (+) SaqGT5
copy AA seq
copy Nt seq
  • ACP19371.1
  • saqG
24390 - 25451 (+) SaqG
copy AA seq
copy Nt seq
  • ACP19372.1
  • saqH
25448 - 26428 (+) SaqH
copy AA seq
copy Nt seq
  • ACP19373.1
  • saqZ3
26500 - 27468 (+) SaqZ3
copy AA seq
copy Nt seq
  • ACP19374.1
  • saqQ
27470 - 28780 (+) SaqQ
copy AA seq
copy Nt seq
  • ACP19375.1
  • saqGT6
28780 - 30030 (+) SaqGT6
copy AA seq
copy Nt seq
  • ACP19376.1
  • saqR
30089 - 30844 (+) SaqR
copy AA seq
copy Nt seq
  • ACP19377.1
  • saqS
30857 - 32260 (+) SaqS
copy AA seq
copy Nt seq
  • ACP19378.1
  • saqT
32269 - 33279 (+) SaqT
copy AA seq
copy Nt seq
  • ACP19379.1
  • saqW
33585 - 35081 (+) SaqW
copy AA seq
copy Nt seq
  • ACP19380.1
35144 - 35599 (-) hypothetical protein
copy AA seq
copy Nt seq
  • ACP19381.1
35144 - 36193 (-) hypothetical protein
copy AA seq
copy Nt seq
Polyketide-specific information
Subclass Angucycline
Starter unit Acetyl-CoA
Ketide length 9
Cyclic? yes
Polyketide-synthases
Genes Properties Modules
saqL
+
saqA
+
saqF
Synthase subclass: Type II
Saccharide-specific information
Subclass oligosaccharide
Glycosyltransferases
saqGT5
Specificity: D-olivose
Evidence:
  • Knock-out construct
saqGT2
Specificity: L-rhodinose
Evidence:
  • Knock-out construct
saqGT3
Specificity: D-olivose
Evidence:
  • Knock-out construct
saqGT4
Evidence:
  • Sequence-based prediction
saqGT1
Specificity: L-Rhodinose
Evidence:
  • Knock-out construct
saqGT6
Specificity: 2-deoxy-L-fucose
Evidence:
  • Knock-out construct
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: YECXNWBIVB4ZABFMZK4W53HU, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.