BGC0000268: Sch-47554 biosynthetic gene cluster from Streptomyces sp. SCC 2136
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Location: 1 - 77,550 nt. (total: 77,550 nt).
This entry is originally from NCBI GenBank AJ628018.2.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000268
Short description Sch-47554 biosynthetic gene cluster from Streptomyces sp. SCC 2136
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
AJ628018.2
via
Compounds
  • Sch-47554
  • Sch-47555
Species Streptomyces sp. SCC 2136 [taxonomy]
References
Chemical products information
Sch-47554 Evidence:
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C37H38O13
Chemical database entries
NPAtlas
Sch-47555 Evidence:
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C37H42O13
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • CAH10092.1
  • schA1
 498 - 1481 (+) putative transport system permease ABC transporter
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    • CAH10093.1
    • schA2
    		 1515 - 2402 (+) putative Oligogalacturonate transport system permease protein
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      • CAH10094.1
      • schA3
      		 4587 - 5666 (-) putative 3-(2-hydroxyphenyl) propionic acid transporter
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        • CAH10095.1
        • schA4
        		 6218 - 6883 (-) putative TetR family transcriptional regulator
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          • CAH10096.1
          • schA5
          		 7072 - 7965 (+) putative shikimate 5-dehydrogenase
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            • CAH10097.1
            • schA6
            		 8041 - 9921 (+) putative 4-hydroxyphenyl pyruvate dioxygenase
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              • CAH10098.1
              • schA7
              		 10223 - 11704 (+) probable amino acid transporter transmembrane protein s
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                • CAH10099.1
                		 11716 - 12678 (+) hypothetical protein
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                  • CAH10100.1
                  • schA9
                  		 13077 - 13670 (-) putative phosphate mutase
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                    • CAH10101.1
                    • schA10
                    		 13683 - 14561 (-) putative 6-phosphogluconate dehydrogenase
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                      • CAH10102.1
                      • schA11
                      		 14577 - 15980 (-) glucose-6-phosphate isomerase
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                        • CAH10103.1
                        		 16240 - 17175 (-) hypothetical protein
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                          • CAH10104.1
                          • schA13
                          		 17172 - 18848 (-) putative glucose-6-phosphate-1-dehydrogenase
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                            • CAH10105.1
                            • schA14
                            		 18845 - 20005 (-) putative trasnaldolase
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                              • CAH10106.1
                              • schA15
                              		 20025 - 22100 (-) putative transketolase
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                                • CAH10107.1
                                • schA16
                                		 22247 - 23140 (+) putative AraC-family transcriptional regulator
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                                  • CAF31374.1
                                  • schA17
                                  		 23237 - 24619 (-) putative endo-1,3-beta-glucanase
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                                    • CAF31373.1
                                    • schA18
                                    		 25015 - 26022 (-) putative oxidoreductase
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                                      • CAF31372.1
                                      • schA19
                                      		 26093 - 27883 (-) putative Oxidoreductase, alpha subunit
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                                        • CAH10108.1
                                        • schP1
                                        		 28019 - 29872 (-) putative Acyl-CoA carboxylase
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                                          • CAF31370.1
                                          • schP2
                                          		 30033 - 31604 (-) putative methyl malonyl Co-A decarboxylase
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                                            • CAF31369.2
                                            • schS1
                                            		 32312 - 33334 (-) putative dNDP-hexose 3-ketoreductase
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                                              • CAF31368.1
                                              • schS2
                                              		 33361 - 34758 (-) putative NDP-hexose 2, 3-dehydratase
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                                                • CAF31367.1
                                                • schS3
                                                		 35871 - 37175 (-) putative NDP-hexose 3-dehydratase
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                                                  • CAF31366.1
                                                  • schS4
                                                  		 37175 - 38134 (-) putative NDP-hexose 4-keto reductase
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                                                    • CAF31365.1
                                                    • schS5
                                                    		 38166 - 39152 (-) putative dNDP-glucose 4, 6-dehydratase
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                                                      • CAF31364.1
                                                      • schS6
                                                      		 39149 - 40216 (-) putative dNDP-glucose synthetase
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                                                        • CAF31363.2
                                                        • schS7
                                                        		 40301 - 41437 (-) putative C-glycosyltransferase
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                                                          • CAF31362.1
                                                          • schS8
                                                          		 41434 - 42024 (-) putative NDP-hexose 3, 5-epimerase
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                                                            • CAH10109.1
                                                            • schS9
                                                            		 42086 - 43258 (-) putative O-glycosyltransferase
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                                                              • CAH10110.1
                                                              • schS10
                                                              		 43298 - 44590 (-) putative O-glycosyltransferase
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                                                                • CAH10111.1
                                                                • schA20
                                                                		 44623 - 45846 (-) putative transporter
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                                                                  • CAH10112.1
                                                                  • schP3
                                                                  		 45969 - 47792 (-) putative oxidase-reducatse
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                                                                    • CAH10113.1
                                                                    • schP4
                                                                    		 47970 - 48908 (-) putative aromatase
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                                                                      • CAH10114.1
                                                                      • schP5
                                                                      		 48935 - 49735 (-) putative ketoreducatse
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                                                                        • CAH10115.1
                                                                        • schP6
                                                                        		 49768 - 50037 (-) putative acyl carrier protein
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                                                                          • CAH10116.1
                                                                          • schP7
                                                                          		 50097 - 51323 (-) putative chain length factor
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                                                                            • CAH10117.1
                                                                            • schP8
                                                                            		 51320 - 52582 (-) putative ketoacyl synthase
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                                                                              • CAH10118.1
                                                                              • schP9
                                                                              		 52606 - 52932 (-) putative cyclase
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                                                                                • CAH10119.1
                                                                                • schP10
                                                                                		 52990 - 54474 (-) putative oxygenase
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                                                                                  • CAH10120.1
                                                                                  • schP11
                                                                                  		 54705 - 55580 (-) unknown
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                                                                                    • CAH10121.1
                                                                                    • schA21
                                                                                    		 55722 - 56477 (-) putative tetR-family regulatory protein
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                                                                                      • CAH10122.1
                                                                                      		 56595 - 57194 (+) hypothetical protein
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                                                                                        • CAH10123.1
                                                                                        • schA23
                                                                                        		 57209 - 58792 (+) putative transporter
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                                                                                          • CAH10124.1
                                                                                          • schA24
                                                                                          		 58880 - 59998 (+) putative oxidoreducatse
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                                                                                            • CAH10125.1
                                                                                            • schA25
                                                                                            		 60242 - 61093 (+) putative repressor-response regulator
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                                                                                              • CAH10126.1
                                                                                              • schA26
                                                                                              		 62333 - 63931 (-) putative oxidoreducatse
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                                                                                                • CAH10127.1
                                                                                                • schA27
                                                                                                		 64202 - 64954 (-) putative transcriptional regulator
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                                                                                                  • CAH10128.1
                                                                                                  • schA28
                                                                                                  		 65981 - 66589 (+) putative 3-Oxoacyl carrier protein reducatse
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                                                                                                    • CAH10129.1
                                                                                                    		 66593 - 67477 (+) hypothetical protein
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                                                                                                      • CAH10130.1
                                                                                                      • schA30
                                                                                                      		 67521 - 69065 (+) feruloyl-CoA synthetase
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                                                                                                        • CAH10131.1
                                                                                                        • schA31
                                                                                                        		 69585 - 70373 (-) phenyl acetic acid responsive transcriptional repressor
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                                                                                                          • CAH10132.1
                                                                                                          		 70497 - 72167 (-) hypothetical protein
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                                                                                                            • CAH10133.1
                                                                                                            • schA33
                                                                                                            		 72198 - 73847 (-) putative secreted protein
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                                                                                                              • CAH10134.1
                                                                                                              • schA34
                                                                                                              		 74161 - 77076 (-) beta-galactosidae
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                                                                                                                Biosynthesis information
                                                                                                                Annotation changelog

                                                                                                                Entry version: 4

                                                                                                                Date
                                                                                                                Changes
                                                                                                                Submitters
                                                                                                                Reviewers
                                                                                                                2022-10-07
                                                                                                                Update chemical activity to schema version 2.11
                                                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                                                                Entry version: 3

                                                                                                                Date
                                                                                                                Changes
                                                                                                                Submitters
                                                                                                                Reviewers
                                                                                                                2022-09-15
                                                                                                                Updated bioactivity data
                                                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                                                                Entry version: 2

                                                                                                                Date
                                                                                                                Changes
                                                                                                                Submitters
                                                                                                                Reviewers
                                                                                                                2019-10-16
                                                                                                                Migrated from v1.4
                                                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                                                2019-10-16
                                                                                                                Updated compound(s) information (NPAtlas curation)
                                                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                                                                Entry version: 1

                                                                                                                Date
                                                                                                                Changes
                                                                                                                Submitters
                                                                                                                Reviewers
                                                                                                                2015-06-12
                                                                                                                Submitted
                                                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                                                Detailed domain annotation
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