LOCUS       BGC0000270             39428 bp    DNA     linear   BCT 26-JUL-2016
DEFINITION  Streptomyces antibioticus simocyclinone biosynthetic gene cluster,
            partial sequence.
ACCESSION   BGC0000270
VERSION     BGC0000270
KEYWORDS    .
SOURCE      Streptomyces antibioticus
  ORGANISM  Streptomyces antibioticus
            Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
            Streptomyces.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.2.0-924c3663(changed)
            Run date     :: 2022-11-07 18:01:25
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     gene            <1..168
                     /gene="sim2"
     CDS             <1..168
                     /codon_start=1
                     /gene="sim2"
                     /gene_functions="biosynthetic (rule-based-clusters) T2PKS:
                     t2ks"
                     /gene_kind="biosynthetic"
                     /note="ketosynthase"
                     /product="Sim2"
                     /protein_id="AAL15580.1"
                     /sec_met_domain="t2ks (E-value: 3.1e-29, bitscore: 93.4,
                     seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="IPPTANLHDPEPECDLDYVPITAREARLDRVLSVGSGFGGFQSAM
                     VLTRPERNTA"
     source          1..39428
                     /db_xref="taxon:1890"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces antibioticus"
                     /strain="Tu 6040"
     subregion       1..39428
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0000270"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..39428
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /contig_edge="True"
                     /product="T2PKS"
                     /product="aminocoumarin"
                     /region_number="1"
                     /rules="(t2ks and t2clf)"
                     /rules="(novK or novJ or novI or novH or SpcDK_cou)"
                     /subregion_numbers="1"
                     /tool="antismash"
     protocluster    1..36379
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[<0:1379]"
                     /cutoff="20000"
                     /detection_rule="(t2ks and t2clf)"
                     /neighbourhood="35000"
                     /product="T2PKS"
                     /protocluster_number="1"
                     /t2pks_malonyl_elongations="8|9 (Score: 714.3; E-value:
                     8.4e-218)"
                     /t2pks_molecular_weights="acetyl-CoA_8 (Da): 391.434"
                     /t2pks_molecular_weights="acetyl-CoA_9 (Da): 433.470"
                     /t2pks_product_classes="angucycline"
                     /t2pks_product_classes="anthracycline"
                     /t2pks_product_classes="aureolic acid"
                     /t2pks_product_classes="tetracycline"
                     /t2pks_starter_units="acetyl-CoA (Score: 0.0; E-value: 0)"
                     /tool="antismash"
     proto_core      <1..1379
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(t2ks and t2clf)"
                     /neighbourhood="35000"
                     /product="T2PKS"
                     /protocluster_number="1"
                     /t2pks_malonyl_elongations="8|9 (Score: 714.3; E-value:
                     8.4e-218)"
                     /t2pks_molecular_weights="acetyl-CoA_8 (Da): 391.434"
                     /t2pks_molecular_weights="acetyl-CoA_9 (Da): 433.470"
                     /t2pks_product_classes="angucycline"
                     /t2pks_product_classes="anthracycline"
                     /t2pks_product_classes="aureolic acid"
                     /t2pks_product_classes="tetracycline"
                     /t2pks_starter_units="acetyl-CoA (Score: 0.0; E-value: 0)"
     cand_cluster    1..36379
                     /SMILES="NC(Cc1ccc(O)cc1)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(t2ks and t2clf)"
                     /detection_rules="(novK or novJ or novI or novH or
                     SpcDK_cou)"
                     /kind="neighbouring"
                     /product="T2PKS"
                     /product="aminocoumarin"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     gene            165..1379
                     /gene="sim3"
     CDS             165..1379
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (68-403). E-value:
                     6.5e-34. Score: 109.3. Matches aSDomain:
                     nrpspksdomains_sim3_PKS_KS.1"
                     /codon_start=1
                     /gene="sim3"
                     /gene_functions="biosynthetic (rule-based-clusters) T2PKS:
                     t2clf"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093:Beta-ketoacyl synthase (Score: 673.3; E-value:
                     1.6e-204)"
                     /gene_functions="biosynthetic-additional (t2pks) CLF 8|9
                     (Score: 714.3; E-value: 8.4e-218)"
                     /gene_kind="biosynthetic"
                     /note="chain length determinant"
                     /product="Sim3"
                     /protein_id="AAL15581.1"
                     /sec_met_domain="t2clf (E-value: 6.1e-216, bitscore: 707.9,
                     seeds: 26, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTSVVVTGLGVAAPNGLGTADYWAATREGRSGIGRVTRFDPSQY
                     PSRLAGEVPGFVAEDHLPSRLLPQTDHMTRLALVSADWALQDAGIRPEELPEYAAGVVT
                     ASSAGGFEFGQNELRALWSKGSQYVSAYQSFAWFYAVNTGQISIRHGLRGPSGVVVSDQ
                     AGGLDALAQARRQIRRGSQVIVSGGIDASICSWGWGAQLTSGRMSTDDDPATAYRPFDG
                     AAAGHVPGEGGALLVLEEAGAAAARGARVYGRIAGYGTTFDPKPGSGREPGLRRAIELA
                     LTDAGLAPADIDVVFADAAAVPDLDRIEARALVEVFGPRGLPVTAPKSMTGRLNSGAGS
                     LDVATALLAIRDGVIPPTINVTAQDDYELDLVTAQARSARLRSALVVARGHGGFNSALV
                     VQDAA"
     aSDomain        369..1373
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sim3_PKS_KS.1"
                     /domain_subtype="Iterative-KS"
                     /evalue="6.50E-34"
                     /label="sim3_PKS_KS.1"
                     /locus_tag="sim3"
                     /protein_end="403"
                     /protein_start="68"
                     /score="109.3"
                     /tool="antismash"
                     /translation="QTDHMTRLALVSADWALQDAGIRPEELPEYAAGVVTASSAGGFEF
                     GQNELRALWSKGSQYVSAYQSFAWFYAVNTGQISIRHGLRGPSGVVVSDQAGGLDALAQ
                     ARRQIRRGSQVIVSGGIDASICSWGWGAQLTSGRMSTDDDPATAYRPFDGAAAGHVPGE
                     GGALLVLEEAGAAAARGARVYGRIAGYGTTFDPKPGSGREPGLRRAIELALTDAGLAPA
                     DIDVVFADAAAVPDLDRIEARALVEVFGPRGLPVTAPKSMTGRLNSGAGSLDVATALLA
                     IRDGVIPPTINVTAQDDYELDLVTAQARSARLRSALVVARGHGGFNSALVVQDA"
     gene            1428..1694
                     /gene="sim4"
     CDS             1428..1694
                     /NRPS_PKS="Domain: ACP (12-82). E-value: 2.9e-16. Score:
                     51.4. Matches aSDomain: nrpspksdomains_sim4_ACP.1"
                     /codon_start=1
                     /gene="sim4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1129:acyl carrier protein (Score: 117.4; E-value:
                     3.7e-36)"
                     /gene_functions="biosynthetic-additional (t2pks) ACP
                     (Score: 132.1; E-value: 1.3e-41)"
                     /gene_kind="biosynthetic-additional"
                     /note="acyl carrier protein"
                     /product="Sim4"
                     /protein_id="AAL15582.1"
                     /sec_met_domain="PP-binding (E-value: 1e-11, bitscore:
                     36.6, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQTTEFTLDDLRRILRDGAGASEDVDLEGDIIDVAFEDLGYESIA
                     LLETCSRIEREYGISLDDDAVSEAPTPRALVAIVNTHLIAVAG"
     aSDomain        1464..1673
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sim4_ACP.1"
                     /evalue="2.90E-16"
                     /label="sim4_ACP.1"
                     /locus_tag="sim4"
                     /protein_end="82"
                     /protein_start="12"
                     /score="51.4"
                     /tool="antismash"
                     /translation="RILRDGAGASEDVDLEGDIIDVAFEDLGYESIALLETCSRIEREY
                     GISLDDDAVSEAPTPRALVAIVNTH"
     gene            1714..2499
                     /gene="sim5"
     CDS             1714..2499
                     /NRPS_PKS="Domain: PKS_KR (7-161). E-value: 5.3e-13. Score:
                     41.1. Matches aSDomain: nrpspksdomains_sim5_PKS_KR.1"
                     /codon_start=1
                     /gene="sim5"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     264.9; E-value: 1.1e-80)"
                     /gene_functions="biosynthetic-additional (t2pks) KR C9
                     (Score: 487.6; E-value: 1.9e-149)"
                     /gene_kind="biosynthetic-additional"
                     /note="ketoreductase"
                     /product="Sim5"
                     /protein_id="AAL15583.1"
                     /sec_met_domain="adh_short (E-value: 2.4e-41, bitscore:
                     133.0, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPGQKQQVALVTGATSGIGLAVVRALAAQGHQVFFCARNAEKVAV
                     TIKELRGEGLDVDGTSCDVRSVADVKAFVAAAVERFGPVDVLVNNAGRSGGGVTAELTD
                     ELWADVIETNLTSVFMVTREVLTAGGMREKSSGRIVNIASTAGKQGVVLGAPYSASKHG
                     VVGFTKALGNELAPTGITVNAVCPGYVETPMAERVRQGYAAAYGTSEEAILEKFQAKIP
                     LGRYSTPEEVAGLVGYLVSDTAASITAQALNVCGGLGNF"
     aSDomain        1735..2196
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sim5_PKS_KR.1"
                     /evalue="5.30E-13"
                     /label="sim5_PKS_KR.1"
                     /locus_tag="sim5"
                     /protein_end="161"
                     /protein_start="7"
                     /score="41.1"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VALVTGATSGIGLAVVRALAAQGHQVFFCARNAEKVAVTIKELRG
                     EGLDVDGTSCDVRSVADVKAFVAAAVERFGPVDVLVNNAGRSGGGVTAELTDELWADVI
                     ETNLTSVFMVTREVLTAGGMREKSSGRIVNIASTAGKQGVVLGAPYSASK"
     CDS_motif       1741..1803
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sim5_0001"
                     /evalue="3.20E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="sim5"
                     /protein_end="30"
                     /protein_start="9"
                     /score="19.8"
                     /tool="antismash"
                     /translation="LVTGATSGIGLAVVRALAAQG"
     gene            2525..3472
                     /gene="sim6"
     CDS             2525..3472
                     /NRPS_PKS="Domain: Polyketide_cyc2 (7-149). E-value:
                     1.7e-15. Score: 49.5. Matches aSDomain:
                     nrpspksdomains_sim6_Polyketide_cyc2.1"
                     /NRPS_PKS="Domain: Polyketide_cyc2 (158-309). E-value:
                     1.2e-10. Score: 33.8. Matches aSDomain:
                     nrpspksdomains_sim6_Polyketide_cyc2.2"
                     /codon_start=1
                     /gene="sim6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1128:cyclase/dehydrase (Score: 466.1; E-value:
                     8.7e-142)"
                     /gene_functions="biosynthetic-additional (t2pks) CYC C7-C12
                     (Score: 499.6; E-value: 6e-153)"
                     /gene_kind="biosynthetic-additional"
                     /note="cyclase/dehydrase"
                     /product="Sim6"
                     /protein_id="AAL15584.1"
                     /transl_table=11
                     /translation="MSDSGISHVEHTIEVDAPATDVYRLLAEVENWPRIFGPTIHVDHV
                     ERGARTERIRIWATANGAAKSWTSRRELDPEALRIDFRQEVSAPPVAAMGGAWIIEPVS
                     EGACRVRLLHDYRAIDDAPEDLAWIEQAVDRNSRSELAALKANAEVVVGAADELMLSFQ
                     DSVRIDGSAKDVYDFLNEADRWTERLPHVAEVELTEQTPGLQVLTMETRAKDGSTHTTS
                     SVRVCFPHERIVYKQTVLPALMTLHTGYWLLEEDGEGTVATSQHTVIINTANIRAILGE
                     SAGVAEARQYVQTALSTNSRATLGHAKDYAERRD"
     aSDomain        2546..2971
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sim6_Polyketide_cyc2.1"
                     /domain_subtype="Polyketide_cyc2"
                     /evalue="1.70E-15"
                     /label="sim6_Polyketide_cyc2.1"
                     /locus_tag="sim6"
                     /protein_end="149"
                     /protein_start="7"
                     /score="49.5"
                     /tool="antismash"
                     /translation="HVEHTIEVDAPATDVYRLLAEVENWPRIFGPTIHVDHVERGARTE
                     RIRIWATANGAAKSWTSRRELDPEALRIDFRQEVSAPPVAAMGGAWIIEPVSEGACRVR
                     LLHDYRAIDDAPEDLAWIEQAVDRNSRSELAALKANAE"
     aSModule        2546..3451
                     /domains="nrpspksdomains_sim6_Polyketide_cyc2.1"
                     /domains="nrpspksdomains_sim6_Polyketide_cyc2.2"
                     /incomplete
                     /locus_tags="sim6"
                     /tool="antismash"
                     /type="unknown"
     aSDomain        2999..3451
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sim6_Polyketide_cyc2.2"
                     /domain_subtype="Polyketide_cyc2"
                     /evalue="1.20E-10"
                     /label="sim6_Polyketide_cyc2.2"
                     /locus_tag="sim6"
                     /protein_end="309"
                     /protein_start="158"
                     /score="33.8"
                     /tool="antismash"
                     /translation="MLSFQDSVRIDGSAKDVYDFLNEADRWTERLPHVAEVELTEQTPG
                     LQVLTMETRAKDGSTHTTSSVRVCFPHERIVYKQTVLPALMTLHTGYWLLEEDGEGTVA
                     TSQHTVIINTANIRAILGESAGVAEARQYVQTALSTNSRATLGHAKD"
     gene            3478..4962
                     /gene="sim7"
     CDS             3478..4962
                     /codon_start=1
                     /gene="sim7"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050:monooxygenase FAD-binding (Score: 542.6; E-value:
                     1.6e-164)"
                     /gene_functions="biosynthetic-additional (t2pks) OXY
                     (Score: 589.4; E-value: 1.3e-179)"
                     /gene_kind="biosynthetic-additional"
                     /note="oxygenase"
                     /product="Sim7"
                     /protein_id="AAL15585.1"
                     /transl_table=11
                     /translation="MTGPQTDVLVIGAGPVGLMLAGELLLGGARVVVAERLTEPTTESR
                     ASTLHARTMEILDQRGLTGRLGEVPGDGTGHFGGIPLRLDGQQSPYAGLWKVPQSRVEE
                     ILGAWAIGLGAEVRRGRELTGLREDGAVVEAELSCEDGTRELLRARYVVGCDGENSTVR
                     RLAGFEFAGSAASRELIRADVAGIDVPNRRFERLPGGLAIAARRPDGITRVMVHEFGRT
                     ATPRQAEPDFDEMARTWQRVTGEDISHGTPVWINSFGDASRQVTEYRRGRILLAGDAAH
                     AQMPVGGQALNLGLQDAFNLGWKLAAEICGWAPPGLLDSYHEERHAVGSRVLSDIAAQA
                     LLLLGGPEVEALRSVVGRLLGLDAVRDHLATGVGGIGIQYSAHEGDHPLLGARLPDAAL
                     DIEAGAATAWALLRAGTGLLLDVAPEAPGHVDLRAVADGWADRVRVVAARPRAGAVAPT
                     TGAVLVRPDGHVVWADGGADRLRAALVQWFGSADRT"
     gene            5041..5805
                     /gene="sim8"
     CDS             5041..5805
                     /NRPS_PKS="Domain: PKS_KR (7-128). E-value: 9.8e-08. Score:
                     23.9. Matches aSDomain: nrpspksdomains_sim8_PKS_KR.1"
                     /codon_start=1
                     /gene="sim8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     194.9; E-value: 2.6e-59)"
                     /gene_functions="biosynthetic-additional (t2pks) KR C15
                     (Score: 487.4; E-value: 2e-149)"
                     /gene_kind="biosynthetic-additional"
                     /note="oxidoreductase"
                     /product="Sim8"
                     /protein_id="AAL15586.1"
                     /transl_table=11
                     /translation="MKRLAGKTALVTGSSRGIGRATALRLAREGATVAVHYADNADAAK
                     ATLAAIEEEGGRAFLVRAELGVPGDVDTLFQGLTAGLREATGKEELNILVNNAGVMGGV
                     KPEDLTPEIFDRLIAVNAKAPLFLTQRVLSIMPDGGRIINIGTGLLRYANPDEVAYSMS
                     KGALDQISLHFARLLGPRNITVNTVSPGITNNGSPIFDVPEAREFMANMNAFKRIAEPE
                     DVGDVVAFLASDDARWITGTFVDASGGTLLGG"
     aSDomain        5062..5424
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sim8_PKS_KR.1"
                     /evalue="9.80E-08"
                     /label="sim8_PKS_KR.1"
                     /locus_tag="sim8"
                     /protein_end="128"
                     /protein_start="7"
                     /score="23.9"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="TALVTGSSRGIGRATALRLAREGATVAVHYADNADAAKATLAAIE
                     EEGGRAFLVRAELGVPGDVDTLFQGLTAGLREATGKEELNILVNNAGVMGGVKPEDLTP
                     EIFDRLIAVNAKAPLFL"
     CDS_motif       5068..5133
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sim8_0001"
                     /evalue="9.60E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="sim8"
                     /protein_end="31"
                     /protein_start="9"
                     /score="15.1"
                     /tool="antismash"
                     /translation="LVTGSSRGIGRATALRLAREGA"
     gene            5936..6508
                     /gene="sim9"
     CDS             5936..6508
                     /codon_start=1
                     /gene="sim9"
                     /gene_functions="biosynthetic-additional (t2pks) KR (Score:
                     42.0; E-value: 2e-13)"
                     /gene_kind="biosynthetic-additional"
                     /note="reductase"
                     /product="Sim9"
                     /protein_id="AAL15587.1"
                     /transl_table=11
                     /translation="MSSARLRLAVVLGSTREGRLCPTVANWFAGQGRQHGGFDLDLVDP
                     YGLDIPVAPSPEPPAQVVEIGQRLAAADAFVIVTPEYNHSFSAPLKSLIDWHYVQWRAK
                     PVGFVSYGGLAGGLRAVEQLRLVFAELHAATVRDTVSFHNAAQLFDEAGDPRDPEGCNT
                     AAKTMLDQLHWWGRALRQARLERPYQG"
     gene            6516..7202
                     /gene="sim10"
     CDS             6516..7202
                     /NRPS_PKS="Domain: ACPS (124-176). E-value: 2.7e-09. Score:
                     28.7. Matches aSDomain: nrpspksdomains_sim10_ACPS.1"
                     /codon_start=1
                     /gene="sim10"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1012:4'-phosphopantetheinyl transferase (Score: 151.1;
                     E-value: 4.7e-46)"
                     /gene_kind="biosynthetic-additional"
                     /note="putative phosphopantetheinyl transferase"
                     /product="Sim10"
                     /protein_id="AAL15588.1"
                     /transl_table=11
                     /translation="MARTESVQPAEAVQLWLVRPEPVRPDELAALDSEERRRAEAFRGS
                     ADRMLYLSAHLALRRVLAARLGHVAPQEVRIVRDRNGRPTLPGDRPPFHFSLSHSAGLA
                     LLGTAPVRIGVDVQRTLSRTTADLCGRRLHPAEQEELASVQPSARAAHFTRLWTRKEAY
                     LKGLGVGLSRSLAADYLGVDRPDTPAGWTVLDVPCGESHLASAAVQSRSPLPVTLRWLL
                     RSADHV"
     aSDomain        6888..7043
                     /aSDomain="ACPS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sim10_ACPS.1"
                     /evalue="2.70E-09"
                     /label="sim10_ACPS.1"
                     /locus_tag="sim10"
                     /protein_end="176"
                     /protein_start="124"
                     /score="28.7"
                     /tool="antismash"
                     /translation="TADLCGRRLHPAEQEELASVQPSARAAHFTRLWTRKEAYLKGLGV
                     GLSRSLA"
     protocluster    6888..34559
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[16887:24559]"
                     /cutoff="20000"
                     /detection_rule="(novK or novJ or novI or novH or
                     SpcDK_cou)"
                     /neighbourhood="10000"
                     /product="aminocoumarin"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      16888..24559
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(novK or novJ or novI or novH or
                     SpcDK_cou)"
                     /neighbourhood="10000"
                     /product="aminocoumarin"
                     /protocluster_number="2"
     cand_cluster    6888..34559
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="(novK or novJ or novI or novH or
                     SpcDK_cou)"
                     /kind="single"
                     /product="aminocoumarin"
                     /protoclusters="2"
                     /tool="antismash"
     gene            7195..8781
                     /gene="sim11"
     CDS             7195..8781
                     /codon_start=1
                     /gene="sim11"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059:acetyl-CoA carboxylase, carboxyl transferase,
                     (Score: 728.6; E-value: 7.2e-221)"
                     /gene_kind="biosynthetic-additional"
                     /note="carboxyl transferase/decarboxylase"
                     /product="Sim11"
                     /protein_id="AAL15589.1"
                     /transl_table=11
                     /translation="MSDVPSIPADPAPTTRCRLEELRALRQAVADGPDPRATEAQHAKG
                     KLTARERVELLLDGGSFHEVEPLRRHRAQGFGLEARKPHTDGVVVGWGTVHGRTVFVYA
                     HDFRIFGGALGEAHAQKIHKIMDMAIAAGAPLVSLNDGAGARIQEGVTALAGYGGIFQR
                     NTRASGVIPQISVMLGPCAGGAAYSPALTDFVFMVRETSQMFITGPDVVQAVTGEKISQ
                     NGLGGADVHSAVSGVSHFVYDDEQSCIEEVRYLLSLLPSNNREMPPVQLSDDPVDRRND
                     SLLDLVPADGNRPYDMRKVIEEVVDYGEYLEVHERWATNVLCVLARIDGHVTGIIANQP
                     QSLAGVLDISASEKAARFVQMCDAFNIPLVTLLDVPGFLPGVDQEHGGIIRHGAKLLYA
                     YCNATVPRISLILRKAYGGAYIVMDSRSIGADLAYAWPTNEIAVMGAEGAANVIFRRDI
                     AAAEDPDAMRTQKIKEYKAELMHPYYAAERGLVDDVIDPAETRQVLTSALAMLRTKHAD
                     LPSRKHGNPPM"
     gene            8796..9014
                     /gene="sim12"
     CDS             8796..9014
                     /codon_start=1
                     /gene="sim12"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="hypothetical 7.6 kDa protein"
                     /product="Sim12"
                     /protein_id="AAL15590.1"
                     /transl_table=11
                     /translation="MTSDAMTDAIRVESGHLEPEELAALTVVLLARIRGAAPDRAAGDG
                     GSLVAATWRRLERANGFQSPSSWRTAC"
     gene            9056..9829
                     /gene="sim13"
     CDS             9056..9829
                     /NRPS_PKS="Domain: Thioesterase (19-225). E-value: 5.1e-17.
                     Score: 54.9. Matches aSDomain:
                     nrpspksdomains_sim13_Thioesterase.1"
                     /codon_start=1
                     /gene="sim13"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004:thioesterase (Score: 103.8; E-value: 1.3e-31)"
                     /gene_kind="biosynthetic-additional"
                     /note="thioesterase"
                     /product="Sim13"
                     /protein_id="AAL15591.1"
                     /sec_met_domain="PF00561 (E-value: 9.3e-08, bitscore: 23.3,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHSPFEWTVRLRPATGCRSRVVVFPHAGAGPRTYARLLSGLPEDV
                     ELIGVTLPGREHRADLPPGGALCEVVEGTGRELAALPVLPTVYWGHSMGSLLAVTVAGT
                     RDCSVDALVLSAALPGADAVDFAVPLDTPEGLSLMFDRHRLPLTALDADSGRPRADFVL
                     AHDLVLARSALLEVGGVRLGLPLSVFAGAHDPLVPMSTLPKWRDFTTGPFRTEVFEGAH
                     FFPFLPGNGRALLAEITGLLTAAAETRSTTSGASR"
     aSDomain        9113..9730
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sim13_Thioesterase.1"
                     /evalue="5.10E-17"
                     /label="sim13_Thioesterase.1"
                     /locus_tag="sim13"
                     /protein_end="225"
                     /protein_start="19"
                     /score="54.9"
                     /tool="antismash"
                     /translation="RVVVFPHAGAGPRTYARLLSGLPEDVELIGVTLPGREHRADLPPG
                     GALCEVVEGTGRELAALPVLPTVYWGHSMGSLLAVTVAGTRDCSVDALVLSAALPGADA
                     VDFAVPLDTPEGLSLMFDRHRLPLTALDADSGRPRADFVLAHDLVLARSALLEVGGVRL
                     GLPLSVFAGAHDPLVPMSTLPKWRDFTTGPFRTEVFEGAHFFP"
     CDS_motif       9308..9364
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sim13_0001"
                     /evalue="5.00E-04"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="sim13"
                     /protein_end="103"
                     /protein_start="84"
                     /score="11.9"
                     /tool="antismash"
                     /translation="PTVYWGHSMGSLLAVTVAG"
     gene            9826..11196
                     /gene="sim14"
     CDS             9826..11196
                     /codon_start=1
                     /gene="sim14"
                     /note="dioxygenase"
                     /product="Sim14"
                     /protein_id="AAL15592.1"
                     /transl_table=11
                     /translation="MSTRRPYQGAFTPVDQEVTAFDLPVTGRIPAELRGRYLRNGPNPL
                     RLDDPRAHLFLGEGMVHGVRLRDGRAEWYRNRWVRSAAVARSLGEKPRRGTRFAGAEFA
                     PNTHVIGHAGRTLALVENGFRPYELTEELETVGPCDFRGTLQAGYVAHPKLDPHTGELH
                     AVSYATRWEFVQYSVISPTGMVTRTVNIPAPHRPVMHDFALTASYVVLYDLPVVNSLVA
                     AAAGAPMVYDWQENRGARLGLLPRNGTEVRWFDISPCWVFHTLNAYEDGDRVVVDVIRY
                     PRMFTGLRLDGNSTPTMDRWVIDTVSGRVTETRLDDRAQEFPGVNPAVVSGPHRYGYAA
                     VVPDMHTYFGPDDDLDDLPDQAYSDALIKHDFSAGSSSVRPLGRGHYTGEPVFVATASP
                     AAEDDGYLLAYVHDPDRGASDLVILSAQDFTGEPVATVHLPARVPLGLHGSWIADPA"
     gene            11213..12553
                     /gene="sim15"
     CDS             11213..12553
                     /codon_start=1
                     /gene="sim15"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017:aldehyde dehydrogenase (Score: 308.5; E-value:
                     1e-93)"
                     /gene_kind="biosynthetic-additional"
                     /note="aldehyde dehydrogenase/alcohol dehydrogenase"
                     /product="Sim15"
                     /protein_id="AAL15593.1"
                     /transl_table=11
                     /translation="MHPVPAPEQPGELIARLRAASRTGRPRSLEWRTEQLTRLRSLLQE
                     HTDALAEALFADLHKSRSEAHAAEIGFTVREIDHLLENLEEWLRPQPAAVPGCPAGSTA
                     YVQYDPLGVVLVIAPWNYPVQLLLVPVAGALAAGNTVVAKPSEVAPACSALLARLIPQY
                     LSRDAVAVVEGGVAETTALLAQRFDHIFYTGNGTVGRIVMRAAAEHLTPVTLELGGKSP
                     VFVDRGTNLADTATRLARAKFANAGQTCVAPDYVLTDPDTARGLVAEIARSVRRMFGSE
                     PELARGYGRIVNLHHFDRVVRLLGSGRIVLGGRHDRENRYIAPTVLADVAAESPVMREE
                     IFGPVLPIVEVPGVDQAISFINDRDKPLAVYGFTAREEVRRRLAEETTSGGLVLGMPMA
                     QVLDPGLPFGGVGESGTGSYRGAHSLAAFSHLKPVLDVPMRPTGPVG"
     gene            complement(12504..13289)
                     /gene="sim16"
     CDS             complement(12504..13289)
                     /codon_start=1
                     /gene="sim16"
                     /gene_functions="regulatory (smcogs) SMCOG1239:TetR family
                     transcriptional regulator (Score: 188.9; E-value: 1.8e-57)"
                     /gene_kind="regulatory"
                     /note="putative transcription regulator"
                     /product="Sim16"
                     /protein_id="AAL15594.1"
                     /transl_table=11
                     /translation="MWMNENEPVSIWMHPEPAGRRSARSHRTLSRDQIVRAAVKVADTE
                     GVEAASMRRVAAELGAGTMSLYYYVPTKEDLVELMVDEVIGETRLPDRPGPDWRAALTL
                     AANEKRALWLRHPWLATAWRNGHPVWGPNSLRQQEFVLGTLGVFDLQVDELLSLIGLYN
                     GYVESFVRNEVGWLEEARRTKVDMREWMRRSGPYAQQLVDSGEYPMFARVLAETVAPHM
                     GPDQRFRSGLERLLDSIGASLDRLSPPGRSAASERPALA"
     gene            13386..14990
                     /gene="sim17"
     CDS             13386..14990
                     /codon_start=1
                     /gene="sim17"
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 376.3; E-value:
                     2.8e-114)"
                     /gene_kind="transport"
                     /note="transporter"
                     /product="Sim17"
                     /protein_id="AAL15595.1"
                     /transl_table=11
                     /translation="MPDEDAVAVEARPEAPRRPAPRYRGLGVLAVLLGLALSMLDQVIV
                     GTALPTIVGELGGLDELSWVVTAYMVASAAVIPIWGKLSDLYGRRGTYITALVIFLAGS
                     VLAGMAQNMTEIIVFRALQGLGSAGLMVGTFTLIGVLATGPADRIRMQTMIGIVMPVAL
                     GAGPLLGGLLTEHVGWRWSFFINVPLCLVALVASALGIPRSPRREKVRIDVLGSVQLTG
                     GVVALTLLLSWAGTRYDWISAPILGLAAVSAALLATLALTQRRAVEPILPSRLFRTRDF
                     TLAQVVGLLVGAGLLGVLVYFPQYLQQVLGVTPTSSGLLLLPFLIGMIVMELAVARRVV
                     KTGPLPVYPIAGGVVAVVGALAMLALGTGTSVLAAALIPLAAGLGIGVLMQSSLIISFA
                     CQTDQRDLGAASGVLNLFRTIGGSLGVAVLGSLFSARVEHVLTERIGAHAGRSLAAASG
                     RSTPADIRALPAPVRDAFQSAVVGGLHSVVIGMVVIGVLALATSFFFRRLNIPGPFGQG
                     PGPRPDGNTVSSARNAG"
     gene            15202..16083
                     /gene="sim18"
     CDS             15202..16083
                     /codon_start=1
                     /gene="sim18"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="conserved hypothetical protein"
                     /product="Sim18"
                     /protein_id="AAL15596.1"
                     /transl_table=11
                     /translation="MFCEGAGQVTTRGSLVGISDLHVHYEDNRRVVERLRPESADDWLL
                     LAGDVAETVEDIAWAMDLLRGRFAKVVWAPGNHELWTPPYDQVQLRGEARYRHLVELCR
                     GLGVVTPEDPYPVWDGPGGPVAIAPLFVLYDYSFRSDGARDEQDALALAEDAGVICTDE
                     FMLHADPFPSRADWCRARVEYTEARLAAVDEALPTVLVNHYPLVRTPTRVLRHPEFALW
                     CGTEATADWHRRFRAAAVVYGHLHIPSLLYEDGVPHHEVSLGYPSEWQRRPAAPGRLVR
                     ILPEPAATGSRA"
     gene            16080..16742
                     /gene="sim19"
     CDS             16080..16742
                     /NRPS_PKS="Domain: ACPS (102-166). E-value: 1.3e-21. Score:
                     68.7. Matches aSDomain: nrpspksdomains_sim19_ACPS.1"
                     /codon_start=1
                     /gene="sim19"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1060:4'-phosphopantetheinyl transferase (Score: 231.5;
                     E-value: 1.3e-70)"
                     /gene_kind="biosynthetic-additional"
                     /note="putative 4'-phosphopantetheinyl transferase"
                     /product="Sim19"
                     /protein_id="AAL15597.1"
                     /transl_table=11
                     /translation="MIEHVLSRPVVAVDTFTDPVEPPVLFREEEELIARAVDARRSEFG
                     TVRACARAALAVLGIDAVPILRGPCGEPVWPAGVVGSMTHCEGYRAAAVAREGELAAVG
                     IDAEPHRPLPGDELDVIARPEELGPLSGLRVRWPEICWDRLLFSAKESVYKAWFPLTGR
                     WLGFEEALIDFDPEAGSFRARLLVPGPTVGGRRLPGFDGHWLARDGLLLTAVAVPSD"
     aSDomain        16386..16577
                     /aSDomain="ACPS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sim19_ACPS.1"
                     /evalue="1.30E-21"
                     /label="sim19_ACPS.1"
                     /locus_tag="sim19"
                     /protein_end="166"
                     /protein_start="102"
                     /score="68.7"
                     /tool="antismash"
                     /translation="VGIDAEPHRPLPGDELDVIARPEELGPLSGLRVRWPEICWDRLLF
                     SAKESVYKAWFPLTGRWLG"
     gene            16888..17598
                     /gene="simK"
     CDS             16888..17598
                     /codon_start=1
                     /gene="simK"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     aminocoumarin: novK"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     123.2; E-value: 2.1e-37)"
                     /gene_functions="biosynthetic-additional (t2pks) KR (Score:
                     83.2; E-value: 5.5e-26)"
                     /gene_kind="biosynthetic"
                     /note="putative reductase; similar to NovK of novobiocin
                     biosynthetic gene cluster"
                     /product="SimK"
                     /protein_id="AAL15598.1"
                     /sec_met_domain="novK (E-value: 7.5e-110, bitscore: 357.5,
                     seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAPVAIVAGAVRGTGSVVAVRLAEAGWDVAVLCADGAGNADTVHR
                     VRAVGRRALAVETDVTDAVSVQAALDRVCAELGDPGVLVNSVGVIACGAPGEASEEDWN
                     AVVGRSLRGLFVTSRAVTDLMIRQGRGRIVTIANLLGPAEGGPHDHATVLAGMAGFTRT
                     VALELRAFDITVNAVAPAPPVVGMQAPAAPTAADPEGSRCATQAAEAVLFLVGGGASSV
                     TGQTVQVGDEEAAA"
     gene            17635..19194
                     /gene="simL"
     CDS             17635..19194
                     /NRPS_PKS="Domain: AMP-binding (15-415). E-value: 3.4e-63.
                     Score: 205.4. Matches aSDomain:
                     nrpspksdomains_simL_AMP-binding.1"
                     /codon_start=1
                     /gene="simL"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     264.1; E-value: 3.4e-80)"
                     /gene_kind="biosynthetic-additional"
                     /note="amide synthetase; similar to novobiocic acid
                     synthetase NovL"
                     /product="SimL"
                     /protein_id="AAL15599.1"
                     /sec_met_domain="AMP-binding (E-value: 1.1e-65, bitscore:
                     213.1, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEGNEHYVRQILNTLRADPSGVALVHRDTPVIAGDLADSITSAAE
                     AMRGSGVGVGSVVGILTDPNTPATLVARYAANLLGATVVHLFGVNAANPSDLLSAEAQG
                     GIVAEALPAMVVVDAANLERARAIREVPSVRPVLSGLGELGHDVIDLTDSPAGAFRPDA
                     ARDGDTAVVTFSSGSTGRPKGTAWSFRVKADMVAASARRAQKATALVTAPLTHSNGFVA
                     DDVLVSGGTVVLLPGFDETEVLRSVARYQVNRLAVSAPQLYALADHPETTRTDLSSVRD
                     LFYTGVAASPERVAVAEKVFGSVLMQVYGTSETNIISWLIAGEHTDAGLRATVGRPLEW
                     LRVTIRDPQDERVLPTGETGEVWVNSPWRMDHYWNDPEQTARTVRDGWIRTGDVGHLDD
                     AGYLHLHGRLAGVIKTNGIKVYPVAVERSLLDHPDVAEAAVFGVENSDRVERIHAVVVL
                     REGAGAGPEDLRQHVSSHLSPNHAPADIELRSSLPLIGFGKPDKLRLRADAMARREATH
                     GE"
     aSDomain        17680..18879
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_simL_AMP-binding.1"
                     /evalue="3.40E-63"
                     /label="simL_AMP-binding.1"
                     /locus_tag="simL"
                     /protein_end="415"
                     /protein_start="15"
                     /score="205.4"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="RADPSGVALVHRDTPVIAGDLADSITSAAEAMRGSGVGVGSVVGI
                     LTDPNTPATLVARYAANLLGATVVHLFGVNAANPSDLLSAEAQGGIVAEALPAMVVVDA
                     ANLERARAIREVPSVRPVLSGLGELGHDVIDLTDSPAGAFRPDAARDGDTAVVTFSSGS
                     TGRPKGTAWSFRVKADMVAASARRAQKATALVTAPLTHSNGFVADDVLVSGGTVVLLPG
                     FDETEVLRSVARYQVNRLAVSAPQLYALADHPETTRTDLSSVRDLFYTGVAASPERVAV
                     AEKVFGSVLMQVYGTSETNIISWLIAGEHTDAGLRATVGRPLEWLRVTIRDPQDERVLP
                     TGETGEVWVNSPWRMDHYWNDPEQTARTVRDGWIRTGDVGHLDDAGYLHLHGRLAGVIK
                     T"
     CDS_motif       18142..18195
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_simL_0001"
                     /evalue="1.30E-05"
                     /label="NRPS-A_a3"
                     /locus_tag="simL"
                     /protein_end="187"
                     /protein_start="169"
                     /score="17.9"
                     /tool="antismash"
                     /translation="AVVTFSSGSTGRPKGTAW"
     CDS_motif       18697..18780
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_simL_0002"
                     /evalue="2.10E-06"
                     /label="NRPS-A_a6"
                     /locus_tag="simL"
                     /protein_end="382"
                     /protein_start="354"
                     /score="20.1"
                     /tool="antismash"
                     /translation="PTGETGEVWVNSPWRMDHYWNDPEQTAR"
     gene            19223..22216
                     /gene="simH"
     CDS             19223..22216
                     /NRPS_PKS="Domain: Cglyc (39-248). E-value: 6e-33. Score:
                     106.1. Matches aSDomain: nrpspksdomains_simH_Cglyc.1"
                     /NRPS_PKS="Domain: AMP-binding (413-808). E-value:
                     3.9e-104. Score: 340.3. Matches aSDomain:
                     nrpspksdomains_simH_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (915-982). E-value: 2e-21. Score:
                     67.8. Matches aSDomain: nrpspksdomains_simH_PCP.1"
                     /codon_start=1
                     /gene="simH"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     aminocoumarin: novH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     129.1; E-value: 4.3e-39)"
                     /gene_kind="biosynthetic"
                     /note="peptide synthetase-like protein; similar to NovH of
                     novobiocin biosynthetic gene cluster"
                     /product="SimH"
                     /protein_id="AAL15600.1"
                     /sec_met_domain="novH (E-value: 0.0, bitscore: 1174.0,
                     seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAMPSGSVVSVVEVEGLVDSVVFAAAVDVLLKRHPAPTAGLSWRE
                     VDRSGPDQDSRRTGLDRLATEDGEAVVVGAPPRLTLVRLRADAFQLRLASDRAVLDAPS
                     HRVLLGELLEECAAPAGAVGPAPVEDRVAWTAEGERGEAERAWRIRLAEVDEPTLVAPA
                     GSAGYSQRPERVESELPTDLAERLLVRTDDRRLSLDTIVHAAWGLVLSWLTNRRNVVFG
                     GLRSDRSRFPVAETAVGGFSEIVPVPCAVNPAEPIADLLSRTELDGTLIAEHSALGAAE
                     IHALVGLPRLFDTVAVVEDAGLDPVPAPEGLPGLRVVAQEQWEDFGSALALVVRRSEGG
                     LRLNLDFRPELFTQADAERILAAFSRTFRTIADEPNQPVGRVQLLDDHEQRRILADSDA
                     TADGVPAVTLVELLEQTVARTPGNTVVSFSGQHISYDELNRRVNRLARLLADRGAGPEQ
                     LVALVVPRSIEMVTAVLAVAKTGAGFLPIDPGYPADRIAYMLGDAGPAVVCTTRTAAAV
                     LPQDVSGIVLDDPAVAAEAAGLSDEDPVASEHWAPVPPAALAYVIYTSGSTGRPKGVAV
                     THAGLANLVAAKVERMDVDEQSRILQFASPSFDAFMTELLATIGAGATLVVPPPGILAG
                     DHLAEVLVAERITHVVLPPVAAASVSPESLPDLRSLVLAGEASSGDLIARWAPGRRVIN
                     AYGPTEATVCATMSEPLSADATPPIGGPIPGAACYVLDEALRPVPAGVPGELYLGGAGL
                     ARGYLGRPGMTAERFVANPFAGDGSRMYRTGDLVSWRSDGGLDFLGRSDEQVKLRGFRI
                     ELGEVERVLTNHPGVDRAVAVVREDGAGGRRIVVHLIPSAGAAPTMAELREHAGRFLPD
                     FMVPGAFVLLDAFPLTPNGKLDRRALPEPDAAPAPSGRAPSTPEEIALSRIFSEVLGVA
                     EVDADRNFFELGGNSMVAITVIQKARKAGLAISPKDLVMNPTVEALAAIAGRTDQAPRR
                     AEATTAVK"
     CDS_motif       19253..19330
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_simH_0001"
                     /evalue="4.10E-04"
                     /label="C2_DCL_024-062"
                     /locus_tag="simH"
                     /protein_end="36"
                     /protein_start="10"
                     /score="12.7"
                     /tool="antismash"
                     /translation="VVEVEGLVDSVVFAAAVDVLLKRHPA"
     aSDomain        19340..19966
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_simH_Cglyc.1"
                     /domain_subtype="Cglyc"
                     /evalue="6.00E-33"
                     /label="simH_Cglyc.1"
                     /locus_tag="simH"
                     /protein_end="248"
                     /protein_start="39"
                     /score="106.1"
                     /tool="antismash"
                     /translation="GLSWREVDRSGPDQDSRRTGLDRLATEDGEAVVVGAPPRLTLVRL
                     RADAFQLRLASDRAVLDAPSHRVLLGELLEECAAPAGAVGPAPVEDRVAWTAEGERGEA
                     ERAWRIRLAEVDEPTLVAPAGSAGYSQRPERVESELPTDLAERLLVRTDDRRLSLDTIV
                     HAAWGLVLSWLTNRRNVVFGGLRSDRSRFPVAETAVGGFSEIVPVP"
     aSModule        19340..22168
                     /complete
                     /domains="nrpspksdomains_simH_Cglyc.1"
                     /domains="nrpspksdomains_simH_AMP-binding.1"
                     /domains="nrpspksdomains_simH_PCP.1"
                     /locus_tags="simH"
                     /monomer_pairings="tyr -> tyr"
                     /tool="antismash"
                     /type="nrps"
     aSDomain        20462..21646
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_simH_AMP-binding.1"
                     /evalue="3.90E-104"
                     /label="simH_AMP-binding.1"
                     /locus_tag="simH"
                     /protein_end="808"
                     /protein_start="413"
                     /score="340.3"
                     /specificity="consensus: tyr"
                     /tool="antismash"
                     /translation="EQTVARTPGNTVVSFSGQHISYDELNRRVNRLARLLADRGAGPEQ
                     LVALVVPRSIEMVTAVLAVAKTGAGFLPIDPGYPADRIAYMLGDAGPAVVCTTRTAAAV
                     LPQDVSGIVLDDPAVAAEAAGLSDEDPVASEHWAPVPPAALAYVIYTSGSTGRPKGVAV
                     THAGLANLVAAKVERMDVDEQSRILQFASPSFDAFMTELLATIGAGATLVVPPPGILAG
                     DHLAEVLVAERITHVVLPPVAAASVSPESLPDLRSLVLAGEASSGDLIARWAPGRRVIN
                     AYGPTEATVCATMSEPLSADATPPIGGPIPGAACYVLDEALRPVPAGVPGELYLGGAGL
                     ARGYLGRPGMTAERFVANPFAGDGSRMYRTGDLVSWRSDGGLDFLGRSDEQVKLR"
     CDS_motif       20645..20686
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_simH_0002"
                     /evalue="4.50E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="simH"
                     /protein_end="488"
                     /protein_start="474"
                     /score="10.7"
                     /tool="antismash"
                     /translation="LAVAKTGAGFLPID"
     CDS_motif       20897..20956
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_simH_0003"
                     /evalue="5.30E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="simH"
                     /protein_end="578"
                     /protein_start="558"
                     /score="34.2"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGRPKGVAVTH"
     CDS_motif       21068..21100
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_simH_0004"
                     /evalue="9.90E+01"
                     /label="NRPS-A_a2"
                     /locus_tag="simH"
                     /protein_end="626"
                     /protein_start="615"
                     /score="-2.7"
                     /tool="antismash"
                     /translation="LATIGAGATLV"
     CDS_motif       21308..21334
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_simH_0005"
                     /evalue="6.10E-03"
                     /label="NRPS-A_a5"
                     /locus_tag="simH"
                     /protein_end="704"
                     /protein_start="695"
                     /score="9.4"
                     /tool="antismash"
                     /translation="YGPTEATVC"
     CDS_motif       21437..21526
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_simH_0006"
                     /evalue="1.10E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="simH"
                     /protein_end="768"
                     /protein_start="738"
                     /score="52.8"
                     /tool="antismash"
                     /translation="PAGVPGELYLGGAGLARGYLGRPGMTAERF"
     CDS_motif       21611..21676
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_simH_0007"
                     /evalue="1.40E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="simH"
                     /protein_end="818"
                     /protein_start="796"
                     /score="36.4"
                     /tool="antismash"
                     /translation="FLGRSDEQVKLRGFRIELGEVE"
     aSDomain        21968..22168
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_simH_PCP.1"
                     /evalue="2.00E-21"
                     /label="simH_PCP.1"
                     /locus_tag="simH"
                     /protein_end="982"
                     /protein_start="915"
                     /score="67.8"
                     /tool="antismash"
                     /translation="EIALSRIFSEVLGVAEVDADRNFFELGGNSMVAITVIQKARKAGL
                     AISPKDLVMNPTVEALAAIAGR"
     gene            22228..23478
                     /gene="simI"
     CDS             22228..23478
                     /codon_start=1
                     /gene="simI"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     aminocoumarin: novI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007:cytochrome P450 (Score: 342.6; E-value:
                     4.9e-104)"
                     /gene_kind="biosynthetic"
                     /note="cytochrome P450; similar to NovI of novobiocin
                     biosynthetic gene cluster"
                     /product="SimI"
                     /protein_id="AAL15601.1"
                     /sec_met_domain="p450 (E-value: 6.8e-18, bitscore: 55.8,
                     seeds: 50, tool: rule-based-clusters)"
                     /sec_met_domain="novI (E-value: 1.2e-249, bitscore: 819.0,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNPRPMLSPDVLEDIDLNDRQLHADYDLSEVWRYLRAERPFYYQT
                     ARGSQPGFWVVTRHADCTAVYKDKTNFTAERGNVLPTLLAGGDSASRTMLALTDGDRHT
                     QVRNLLMKAFSPKMLSNIGQSLRTTVDGLLRDAIEKGECDFARDVSGKVPLVAICDLLA
                     VPQEDREYLLSLTAHALSADEADATAEDNWTAKNEILLYFADLAESRRSSGHNDVVSLL
                     ATSSIEGEPLSDGELMANCYGLMIGGDETGRHAITGGLRALIHHPDQWRMLRNGEADLQ
                     TATEEVLRWTVPSLHGARTATADVVVNGKQQIRAGEIVSVWFASANRDEEVFRDADRFD
                     LNRTPNKHLTFAFGPHFCLGHYLARMEVEAILDGLRRMVDDIQQTGPEKLIYSSILQGI
                     SSFPALLKPDRRVPPQT"
     gene            23515..23727
                     /gene="simY"
     CDS             23515..23727
                     /codon_start=1
                     /gene="simY"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1009:mbtH-like protein (Score: 102; E-value: 1.8e-31)"
                     /gene_kind="biosynthetic-additional"
                     /note="MbtH-like protein; similar to CouY of coumermycin
                     biosynthetic gene cluster; involved in aminocoumarin
                     biosynthesis"
                     /product="Sim-cB"
                     /protein_id="AAL15602.1"
                     /transl_table=11
                     /translation="MANPFDDQRGSFLVLRNAEEQVSLWPAFAGVPTGWQVAKGPNSRA
                     ACLAYIEEAWTDLRPKSLIDATDPS"
     gene            23738..24559
                     /gene="simJ1"
     CDS             23738..24559
                     /NRPS_PKS="Domain: PKS_KR (28-199). E-value: 1.1e-19.
                     Score: 62.9. Matches aSDomain:
                     nrpspksdomains_simJ1_PKS_KR.1"
                     /codon_start=1
                     /gene="simJ1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     aminocoumarin: novJ"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     256.2; E-value: 5.3e-78)"
                     /gene_functions="biosynthetic-additional (t2pks) KR (Score:
                     210.4; E-value: 8.5e-65)"
                     /gene_kind="biosynthetic"
                     /note="putative 3-oxoacyl-[ACP]-reductase; similar to NovJ
                     of novobiocin biosynthetic gene cluster"
                     /product="SimJ1"
                     /protein_id="AAL15603.1"
                     /sec_met_domain="adh_short (E-value: 5.4e-38, bitscore:
                     122.1, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 1.2e-34, bitscore:
                     111.6, seeds: 47, tool: rule-based-clusters)"
                     /sec_met_domain="novJ (E-value: 6.3e-141, bitscore: 459.3,
                     seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNQPWPATRADRPNICREGARMSLGADTVAIVTGAGRGIGAATAQ
                     RLAAEGATVAVVDRTEADTADTVASIRAAGGRALGIGCDVTVTDLVEAAVDRTVAEFGR
                     LDVLVNNAGVTRDSLVFMMGDEDWDTVIDVHLNGAARTVRAARRQMVRQGSGRIVNLSS
                     IAALGNQGQANYATAKAAIQGYTRTLAVELGPHGITVNAIAPGFIATTMTDDTARRMGS
                     DPVALRKAVASRVPMRRVGRPEDIAGLVAFLAGPDASYLTGQTIYVDGGPQ"
     aSDomain        23822..24334
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_simJ1_PKS_KR.1"
                     /evalue="1.10E-19"
                     /label="simJ1_PKS_KR.1"
                     /locus_tag="simJ1"
                     /protein_end="199"
                     /protein_start="28"
                     /score="62.9"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VAIVTGAGRGIGAATAQRLAAEGATVAVVDRTEADTADTVASIRA
                     AGGRALGIGCDVTVTDLVEAAVDRTVAEFGRLDVLVNNAGVTRDSLVFMMGDEDWDTVI
                     DVHLNGAARTVRAARRQMVRQGSGRIVNLSSIAALGNQGQANYATAKAAIQGYTRTLAV
                     ELGPHGIT"
     CDS_motif       23828..23896
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_simJ1_0001"
                     /evalue="9.70E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="simJ1"
                     /protein_end="53"
                     /protein_start="30"
                     /score="15.0"
                     /tool="antismash"
                     /translation="IVTGAGRGIGAATAQRLAAEGAT"
     CDS_motif       24212..24271
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_simJ1_0002"
                     /evalue="2.30E-06"
                     /label="PKSI-KR_m4"
                     /locus_tag="simJ1"
                     /protein_end="178"
                     /protein_start="158"
                     /score="20.1"
                     /tool="antismash"
                     /translation="VNLSSIAALGNQGQANYATA"
     gene            24729..25484
                     /gene="sim1"
     CDS             24729..25484
                     /codon_start=1
                     /gene="sim1"
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 143.5; E-value: 1.2e-43)"
                     /gene_kind="regulatory"
                     /note="putative regulator"
                     /product="Sim1"
                     /protein_id="AAL15604.1"
                     /transl_table=11
                     /translation="MRERPSKLTSGGSVVQILTVTDDLQFFEELADDLPNRGFQARRED
                     GIGGALTKCRSVDVILVDLAISETDGFEVCRAIRAVSHVPIIVVSARDDELDQILSLKL
                     GADDYIVWPCGMRQLVARMEALIRRARNAWESWGVPLASAEAGVRQFGPVRIDLQRRSV
                     TRDGHEVPLTRKEFDMLALLATDPGRVFTREQIMFEVWGHDGAGDTRTLGVHVTGIRKK
                     LRMPELVETVRGVGFRLANHTLSEDQAAA"
     misc_feature    24816..24818
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            25806..26546
                     /gene="simJ2"
     CDS             25806..26546
                     /NRPS_PKS="Domain: PKS_KR (6-169). E-value: 6.9e-25. Score:
                     79.8. Matches aSDomain: nrpspksdomains_simJ2_PKS_KR.1"
                     /codon_start=1
                     /gene="simJ2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     232.2; E-value: 1.1e-70)"
                     /gene_functions="biosynthetic-additional (t2pks) KR (Score:
                     206.4; E-value: 1.4e-63)"
                     /gene_kind="biosynthetic-additional"
                     /note="putative 3-oxoacyl-[ACP]-reductase; similar to NovJ
                     of novobiocin biosynthetic gene cluster"
                     /product="SimJ2"
                     /protein_id="AAL15605.1"
                     /sec_met_domain="adh_short (E-value: 3e-43, bitscore:
                     139.2, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVHNGRGVALVTGGSRGIGRAVVLRLVREGFDVAFCYQREAVAAA
                     DLEKAVAELGGRVAHRRVDVSDAVQVKEWVRDVESELGPVEVVVTSAGIVRDGPLVMMQ
                     DKDWQDVIDVNLNGTFNVCRAAVFGMMKRKSGCLINLSSVAGVSGHATQSNYSASKAGI
                     IGFTKSLSKELGRYGIRANVVAPGFIDTDMVAGISDGLRTKAVAGVALGRFGRPDEVAD
                     AVAYLASAEYVTGAVLQIDGGLSI"
     aSDomain        25824..26312
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_simJ2_PKS_KR.1"
                     /evalue="6.90E-25"
                     /label="simJ2_PKS_KR.1"
                     /locus_tag="simJ2"
                     /protein_end="169"
                     /protein_start="6"
                     /score="79.8"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="GVALVTGGSRGIGRAVVLRLVREGFDVAFCYQREAVAAADLEKAV
                     AELGGRVAHRRVDVSDAVQVKEWVRDVESELGPVEVVVTSAGIVRDGPLVMMQDKDWQD
                     VIDVNLNGTFNVCRAAVFGMMKRKSGCLINLSSVAGVSGHATQSNYSASKAGIIGFTKS
                     "
     CDS_motif       25833..25895
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_simJ2_0001"
                     /evalue="8.20E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="simJ2"
                     /protein_end="30"
                     /protein_start="9"
                     /score="15.3"
                     /tool="antismash"
                     /translation="LVTGGSRGIGRAVVLRLVREG"
     CDS_motif       26220..26279
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_simJ2_0002"
                     /evalue="7.10E-06"
                     /label="PKSI-KR_m4"
                     /locus_tag="simJ2"
                     /protein_end="158"
                     /protein_start="138"
                     /score="18.5"
                     /tool="antismash"
                     /translation="INLSSVAGVSGHATQSNYSA"
     gene            26613..28061
                     /gene="sim20"
     CDS             26613..28061
                     /codon_start=1
                     /gene="sim20"
                     /note="dTDP-4-keto-6-deoxyglucose 2,3-dehydratase"
                     /product="Sim20"
                     /protein_id="AAL15606.1"
                     /transl_table=11
                     /translation="MSPTMTLRPERVEPAVVGAGRRFTRSASLIDSTVTPNHVFDRWFA
                     EQRIRNRFEVDRIPFNRLRSWRFHPETGNLGHDSGRFFTVEGLHVETNWGHHPSWTQPI
                     INQPEIGILGIVVKEFDGVLHCLMQAKMEPGNLNTIQLSPTVQATRSNFTGVHGGRGIT
                     FIEYFRDTERSRVLVDSLQSEQASWFLRKRNRNMIVEVTEDIPPHEDFVWLTIGQIHRL
                     LLQDNVVNMDARTVMSCIPFDAPNGGSRWDAPRDFRESLVASMSGEHRSLHSTGEILSW
                     LTDLRTRHALIQRSVPLKDVEHWQVGAEEIAHETGKYFSIIAVDVQAPNREVASWTQPL
                     LAPVECGRVAMIVRRIGGVLHLLLRARLEAGVLNVAEIGPTVQCLPGNYRDVPEEERPP
                     YLDLVLAAGPELLRYDAVQSEEGGRFYQADNRYQIIEVGEEFDIDVAPGFRWMTVEQVT
                     RLLSHSNYLNIQARSMLTGLHTSW"
     gene            28106..29458
                     /gene="sim21"
     CDS             28106..29458
                     /codon_start=1
                     /gene="sim21"
                     /note="putative acyltransferase"
                     /product="Sim21"
                     /protein_id="AAL15607.1"
                     /transl_table=11
                     /translation="MSTRVRLREGRMITSDTAPGTVVRCDSSETMYLARYVSVAFFFER
                     TLDTLRLADGLRGALALVPAFAGRLRAGDGGLEIVCSDAGVPLSVLDVDATLDEARTDV
                     TRPDSMLIDRVDVRTGSLAERPLLTVRVCRTTDGGATLGCSWNHAVGDMSSFMQFVRAW
                     AALVGGTAPPEIRVLDDRMAYLDQVLPDEGIAQPGCEPLDRDAMAGRGPELPPALPDNA
                     AVQLYFGADEVLRMRKSFGEAASRRVSVNDAICAHLVATLRDSEAEPTSWNLSVSVDLR
                     HHLGLPRSVIGNLVQSLYVPCPQTGAGELSGHIRAGLDDFIRSHQCLRADRAFIGPVGR
                     SRFHHCAPVPFDPGHRTFILTNWTRMGVYDVEFEGQRPTFFSPIVSSHAPFTWFAMVAE
                     GPWNEGFLVTAVLPAKAAEQLRSPEGRAALHRFAATDDPCSWGPHRQVTHG"
     gene            29537..29815
                     /gene="sim22"
     CDS             29537..29815
                     /codon_start=1
                     /gene="sim22"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="hypothetical protein"
                     /product="Sim22"
                     /protein_id="AAL15608.1"
                     /transl_table=11
                     /translation="MCGAPGTARRGGRELEAMRRLALLGCTTVTEPDVPVPFDILQRPF
                     ADSNAFVRAAAAASKAVAPVVNGAEAVARSVALTVAEAHVSREHSAA"
     gene            29841..30728
                     /gene="sim23"
     CDS             29841..30728
                     /codon_start=1
                     /gene="sim23"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 262.7; E-value:
                     6.8e-80)"
                     /gene_kind="biosynthetic-additional"
                     /note="glucose-1-phosphate thymidylyltransferase"
                     /product="Sim23"
                     /protein_id="AAL15609.1"
                     /transl_table=11
                     /translation="MRGIILAGGNGTRLAPMTSVVSKQLLPVYGKPMIYYPLSVLLSVG
                     ITDILVIARPQDLPLFERLLGDGSRFGACFDYAEQETPRGLADALIVGREHVGDDDVAL
                     ILGDNIFHGHDFGSIVADAIKNNVGATLFAYEVSDPERYGVVRVDRFGTLLDVVEKPSN
                     PPSNLAITGFYLFDNDALDVAAGLSPSPRGELEITDVIKHFVDRGLARAVPLTDGFVWL
                     DAGTPDSYVDACNYVQAIETRQGRMIACPEEVAFVKGLTGEDQLLAAAAEFGSSEYGRY
                     LTRLAGRFIERSAA"
     gene            30725..31684
                     /gene="sim24"
     CDS             30725..31684
                     /NRPS_PKS="Domain: NAD_binding_4 (4-181). E-value: 1.1e-17.
                     Score: 55.8. Matches aSDomain:
                     nrpspksdomains_sim24_NAD_binding_4.1"
                     /codon_start=1
                     /gene="sim24"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score:
                     314.3; E-value: 1.6e-95)"
                     /gene_kind="biosynthetic-additional"
                     /note="dTDP-glucose 4,6-dehydratase"
                     /product="Sim24"
                     /protein_id="AAL15610.1"
                     /sec_met_domain="NAD_binding_4 (E-value: 7.4e-18, bitscore:
                     55.8, seeds: 102, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 1.9e-16,
                     bitscore: 51.3, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="RmlD_sub_bind (E-value: 3.7e-22, bitscore:
                     70.0, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVAVTGGAGFIGSNFVRDLVGERFAALDVQHVVVLDNLTYAGTL
                     DNLTGVLDDVEFHRTDICDTQAVTRQIVGCDAVVHFAAESHVDRSISSGLPFMRSNVLG
                     TQSVLEAAAAAGAARFVHISTDEVYGSIPVGATGEDAPLAPNSPYAASKAGSDLVALAF
                     ARTHGLPVTVTRCSNNYGPYQNPEKAIPHFVTTLLRGGDIPLYGAGTNVRDWLHVGDHG
                     KAVALLLAGTPKEQVYNIGGGHQITNLQLAHIILDELGLDADRVSFVPDRKAHDARYCV
                     DDSRLREEFGYRPERDFAEAIRETISWYSDNRSWWTHD"
     aSDomain        30737..31267
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sim24_NAD_binding_4.1"
                     /evalue="1.10E-17"
                     /label="sim24_NAD_binding_4.1"
                     /locus_tag="sim24"
                     /protein_end="181"
                     /protein_start="4"
                     /score="55.8"
                     /tool="antismash"
                     /translation="VTGGAGFIGSNFVRDLVGERFAALDVQHVVVLDNLTYAGTLDNLT
                     GVLDDVEFHRTDICDTQAVTRQIVGCDAVVHFAAESHVDRSISSGLPFMRSNVLGTQSV
                     LEAAAAAGAARFVHISTDEVYGSIPVGATGEDAPLAPNSPYAASKAGSDLVALAFARTH
                     GLPVTVTRCSNNYG"
     CDS             32084..32932
                     /codon_start=1
                     /note="Orf25"
                     /product="endonuclease/N-glycosylase"
                     /protein_id="AAL15611.1"
                     /transl_table=11
                     /translation="MAESKPRKAAAPKQAAKQSAVKPKQPEPHLAMVRRARKINRILAE
                     TYPYAHPELDFENPFQLLIATVLSAQTTDLRVNQTTPALFAKYPTPEDLAAANPEGVEE
                     ILRPCGFFRAKTRSVIGLSKALTEDFGGEVPGKLEDLVKLPGVGRKTAFVVLGNAFGRP
                     GITVDTHFQRLVRRWKWTDETDPDKIEAVVGALFPKSDWTDLSHHVIWHGRRICHARKP
                     ACGACPIAPLCPAYGEGETDPEKAKKLLKYEKGGYPGQRLNPPQAYLDAGGKPAPPLGA
                     G"
     CDS             32979..33680
                     /codon_start=1
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="Orf26"
                     /product="hypothetical protein"
                     /protein_id="AAL15612.1"
                     /transl_table=11
                     /translation="MTMTYTHDTHRGPVMLSKEGLPGWLDPVVRAVETVEPLQLSRFLP
                     PENGSGRQSAVLILFGDGEHGPELLLMERAGSLRSHAGQPSFPGGALDPEDGDAHSDGP
                     LRAALREAEEETGLDPAGVQLFGVLPALYIPVSGFVVTPVLGWWREPSPVGVVDPNETA
                     RVFTVPVADLTDPANRATTVHPSGHRGPAFLVESALVWGFTAGVIDRLLHFAGWERPWN
                     RENEVPLDWRS"
     CDS             33685..34893
                     /codon_start=1
                     /note="Orf27"
                     /product="serine proteinase"
                     /protein_id="AAL15613.1"
                     /transl_table=11
                     /translation="MSSVNVLDILLLVAAVWFAVVGYRQGFVVGILSVIGFLGGGLVAV
                     YTLPVIWDAVTDNAEVGTTAAVVAVVVVIVCASIGQALTTHLGNKLRRYITWSPARALD
                     ATGGALVNVVAMLLVAWLIGSALAQTTLPTLGKEVRNSKVLLGVSEALPAAADTWFKDF
                     TSVLAQNGFPQVFSPFSNEPIKDVQPPDPALANSPVATRAQRSIVKVTGTAQSCGKVLE
                     GTGFVFADRRVMTNAHVVGGVDAPSVQIGGEGRKYGAKVVLYDWKRDIAVLDVPDLKAN
                     ALRFTTQDAAGGDGAIVAGFPENGSYDVRAARVRGRITANGPDIYHRGTVSRDVYSLYA
                     TVRQGNSGGPLLTPDGKVYGVVFAKSLDDADTGYALTADEIKQDISQGRAANEQVGTDS
                     CAL"
     CDS             complement(35387..36295)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036:alpha/beta hydrolase fold protein (Score: 136.2;
                     E-value: 2.9e-41)"
                     /gene_kind="biosynthetic-additional"
                     /note="Orf28"
                     /product="hydrolase"
                     /protein_id="AAL15614.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 6.7e-24, bitscore:
                     77.0, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 3.7e-23, bitscore: 73.7,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRIDLPHGEKVTHRDVAANGARFHIAELGDGPLVLLLHGFPQFWW
                     TWRHQLVALADAGYRAVAMDLRGVGGSDRTPRGYDPANLALDVTGVIRSLGEPDAALVG
                     HDLGGYLAWTAAAMRPKLVRRLAVVSMPHPRRWRSAMLRDARQTAASSYIWGFQRPWIP
                     ERQLTADDGALVGRLIREWSGPRLPEDADVETYQRAMCIPSTAHCAIEPYRWLVRSLAR
                     PDGIQFNRRMKRPVRVPTLHLHGSLDPVTRTRSAAGSGEYVEAPYRWRLFDGLGHFPHE
                     EDPAAFSSELINWLKDPEPDR"
     CDS             complement(36319..36807)
                     /codon_start=1
                     /note="Orf29"
                     /product="probable integral membrane protein"
                     /protein_id="AAL15615.1"
                     /transl_table=11
                     /translation="MSAPDGSPVGAERSIGQLVASATTEMSALVHDEIALAKAQLRQDV
                     KRGATSGGAFGAAGMVLLFSLPMLNFALAYGIRTWTGWNLAICFVLSFAANVLVAGLLT
                     LIGMAFAKKLKKSQGPQMVAASMKETAGVLQNAKPHPRPELPQDRAPEAIEAVARSSS"
     CDS             complement(36863..38305)
                     /codon_start=1
                     /note="Orf30"
                     /product="sodium/proton antiporter"
                     /protein_id="AAL15616.1"
                     /transl_table=11
                     /translation="MAAPRTPNTARKVLGRLSLPERTFVADALRTETVGGVLLLVATVT
                     ALVWANIPALQHSYEAVSHFHFGPSALGLNLSVAHWAADGLLAVFFFVAGIELKRELVA
                     GDLRDPRAAVLPVVAALCGMAVPALVYTLTNLTGHGSTQGWAVPTATDIAFALAVLAVI
                     GTSLPSALRAFLLTLAVVDDLFAILIIAIFFTERINFAALGGAVAGLAVFWLLLRKGVR
                     GWYVYVPLAVVVWALMYNSGVHATIAGVAMGLMLRCTTREGEEHSPGEHIEHLVRPLSA
                     GLAVPLFALFSAGVVVSGGALGDVFTEPETLGVVLGLVVGKTLGIFGSTWLTARFTHAE
                     LSEDLEWADIFAVASLAGIGFTVSLLIGELAFAGDTLLTDEVKAAVLTGSLIAALCATV
                     LLKIRNARYRGLCEDEERDEDRDGIPDVYEQDDPAYHLRMADIFERKAAEHRRIAAEKA
                     AAARHGGAEVPGGAGEEDGRPA"
     CDS             complement(38511..39428)
                     /NRPS_PKS="Domain: AMP-binding (1-176). E-value: 8.8e-36.
                     Score: 115.1. Matches aSDomain:
                     nrpspksdomains_AAL15617.1_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     173.8; E-value: 7.6e-53)"
                     /gene_kind="biosynthetic-additional"
                     /note="Orf31"
                     /product="acetyl-coenzyme A synthetase"
                     /protein_id="AAL15617.1"
                     /transl_table=11
                     /translation="MEKYRVTILYTAPTAIRTFMKWGDDIPAQFDLSSLRVLGSVGEPI
                     NPEAWVWYRKHIGADRTPVVDTWWQTETGAMMISPLPGVTETKPGSAQRPLPGISATVV
                     DDEANEVPNGGGGYLVLTEPWPSMLRTIWGDDQRFIDTYWSRFEGKYFAGDGAKKDDDG
                     DIWLLGRVDDVMLVSGHNISTTEVESALVSHPSVAEAAVVGATDETTGQAIVAFVILRG
                     TASEDDKLISQLRDHVGATLGAIAKPKRILPVAELPKTRSGKIMRRLLRDVAENRQLGD
                     VTTLTDSTVMDFIQAKLPAAPSED"
     CDS_motif       complement(38865..38927)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AAL15617.1_0001"
                     /evalue="6.90E-04"
                     /label="NRPS-A_a8"
                     /locus_tag="AAL15617.1"
                     /protein_end="188"
                     /protein_start="167"
                     /score="12.5"
                     /tool="antismash"
                     /translation="LGRVDDVMLVSGHNISTTEVE"
     aSDomain        complement(38901..39425)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AAL15617.1_AMP-binding.1"
                     /evalue="8.80E-36"
                     /label="AAL15617.1_AMP-binding.1"
                     /locus_tag="AAL15617.1"
                     /protein_end="176"
                     /protein_start="1"
                     /score="115.1"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="EKYRVTILYTAPTAIRTFMKWGDDIPAQFDLSSLRVLGSVGEPIN
                     PEAWVWYRKHIGADRTPVVDTWWQTETGAMMISPLPGVTETKPGSAQRPLPGISATVVD
                     DEANEVPNGGGGYLVLTEPWPSMLRTIWGDDQRFIDTYWSRFEGKYFAGDGAKKDDDGD
                     IWLLGRVDDVML"
ORIGIN
        1 atcccgccga cggccaacct gcacgatccc gagcccgagt gcgacctcga ctacgtgccg
       61 atcaccgccc gcgaggcgcg gctggaccgc gtgctgagtg tgggcagcgg cttcggaggc
      121 ttccagagtg ccatggtgct cactcgtccg gagaggaaca cggcatgacc acctccgtcg
      181 tcgtcaccgg gcttggtgtc gcggccccca acgggctggg cacggcggac tactgggccg
      241 ccacccggga ggggcgcagc ggcatcggcc gggtgacccg gttcgacccg tcgcagtacc
      301 cgtcccgcct ggccggcgag gtgccggggt tcgtcgcgga agaccacctg cccagccggc
      361 tgctgccgca gaccgatcac atgaccaggc tcgccctggt cagcgccgac tgggcgttgc
      421 aggacgccgg gatccgaccg gaggagcttc cggagtacgc cgcgggcgtg gtcacggcca
      481 gttccgcggg cggcttcgag ttcggccaga acgagctgcg tgccctgtgg agcaagggca
      541 gccagtacgt cagcgcgtac cagtccttcg cctggttcta cgccgtcaac actggtcaga
      601 tctcgatccg gcacggactg cgcggcccga gcggggtcgt ggtgagcgac caggccggtg
      661 ggctggacgc gctcgcgcag gcgcgtcggc agatccgccg cggcagccag gtcatcgtgt
      721 ccgggggcat cgacgcctcc atctgctcgt ggggctgggg ggcgcaactc accagtggac
      781 ggatgagcac cgacgacgat ccggccaccg cctaccggcc cttcgacgga gcggccgccg
      841 ggcacgtccc gggcgagggc ggtgccctgc tcgtcctgga ggaagcggga gcggcggccg
      901 cccgtggcgc ccgggtgtac ggccggatcg ccggctatgg caccaccttc gacccgaagc
      961 cgggaagcgg ccgtgagccc gggctccgtc gggcgatcga actcgcgctg acggacgccg
     1021 gcctcgcacc cgccgacatc gacgtggtgt tcgccgacgc cgcggccgtc cccgacctcg
     1081 accggatcga ggcgcgggcg ctcgtcgagg tcttcggccc ccgcgggttg ccggtcaccg
     1141 cgcccaagtc gatgacgggc cggctgaatt cgggagcggg ctcactggac gtggcgaccg
     1201 ccctgctggc catccgggac ggcgtcatcc cgccgaccat caatgtcacg gcccaggacg
     1261 actacgagct ggacctggtc accgcgcagg cccggtcggc ccggctgcgc tcggctctgg
     1321 tggtggcgcg cgggcacggc ggcttcaact cggcgctggt ggttcaggac gccgcctgac
     1381 accggcgggg aactcaagca acgacatccc aggaaggaca caagaacatg cagaccaccg
     1441 agttcacgct ggacgacctc cggcgcatcc tgcgcgacgg cgccggcgcc tcggaggacg
     1501 tcgacctcga aggcgacatc atcgacgtcg ccttcgagga tctgggctac gagtcgatcg
     1561 cgctgctgga gacctgcagc cggatcgagc gcgagtacgg aatctcgctg gacgacgacg
     1621 cggtctcgga ggccccgacg ccccgtgccc tggtcgcgat cgtcaacacc cacctcatcg
     1681 ccgttgccgg ctgatcggat acaggagaac aacatgcccg ggcagaagca gcaggtggcg
     1741 cttgtcaccg gcgccaccag tggaatcggc ctggccgtcg tgcgggcact cgcggcccag
     1801 ggacaccagg tgttcttctg cgcccgcaac gcggagaagg tcgcggtcac gatcaaggaa
     1861 ctgcgcgggg agggtctcga cgttgacggg accagctgcg acgtgcggtc ggtcgcggat
     1921 gtcaaggcct tcgtcgcggc ggccgtggag cggttcggtc cggtggacgt gctggtcaac
     1981 aacgccggcc gaagcggcgg cggggtgacc gcggagctca cggacgagct gtgggccgac
     2041 gtcatcgaga ccaacctcac cagcgtgttc atggtcaccc gcgaggtgct caccgccggc
     2101 ggaatgcgcg agaagtcgag cggacgcatc gtcaacatag cctccaccgc aggcaagcag
     2161 ggagttgtcc tcggcgcgcc ctactcggcc tccaagcacg gcgtggtcgg tttcaccaag
     2221 gcgctgggca acgagctggc gcccactggc atcaccgtca acgcggtctg ccccggctat
     2281 gtcgagaccc ccatggcgga gcgggtccgc caggggtacg cggccgctta cggcacgtcc
     2341 gaggaggcga tcctcgagaa gttccaggcc aagatcccgc tgggccgcta ctcgacgccc
     2401 gaggaggtgg ccggactggt cggctacctg gtctcggaca ctgccgcctc gatcaccgcc
     2461 caggcactca acgtctgcgg cgggcttggc aacttctgag accgaccgac cgcaaggaga
     2521 caccatgtcc gactcgggca tcagccacgt cgagcacacc atcgaggtgg acgcaccggc
     2581 aacagacgtc taccggctgc tggcggaggt cgagaactgg ccgcggatct tcgggccgac
     2641 catccacgtg gatcacgtcg agcgcggtgc gcgcaccgag cggatccgca tctgggccac
     2701 cgccaacggt gcggccaaga gttggacctc ccggcgggag ctcgaccccg aggcgctgcg
     2761 aatcgacttc cgccaggagg tctccgcccc gccggtggcc gcgatgggcg gcgcatggat
     2821 catcgagccg gtgtccgagg gcgcctgccg agtccggctg ctgcacgact accgggcgat
     2881 cgacgacgcc ccggaggatc tggcatggat cgagcaggcg gtggaccgca acagccggtc
     2941 cgagctcgcg gccctcaagg ccaacgccga agtggtggtc ggcgccgccg acgagctgat
     3001 gctgtccttc caggactcgg tgcggatcga cggctcggcc aaggacgtct atgacttcct
     3061 gaacgaggcg gaccgctgga ccgagcggct tccccacgtg gccgaggtcg agctgaccga
     3121 gcagaccccg gggctgcagg tgctgacgat ggaaacccgt gccaaggacg gctccaccca
     3181 caccaccagc tcggtgcgcg tctgcttccc gcacgagcgc atcgtctaca agcagaccgt
     3241 gcttccggcc ctgatgacgt tgcacaccgg gtactggctg ctggaggaag acggcgaggg
     3301 caccgtcgcg acctcccagc acaccgtgat catcaacacc gcgaacatcc gcgcgatcct
     3361 cggcgagtcg gcgggcgtcg ccgaggcgcg gcagtacgtc cagaccgcgc tgagcaccaa
     3421 cagccgggcg acccttggcc acgccaagga ctacgccgag cgtcgggact gaccgcgatg
     3481 accggtccgc agacggacgt cctggtgatc ggtgccggac ccgtgggcct gatgctggcc
     3541 ggcgagctgc tcctcggcgg cgcccgggtg gtcgttgccg agcgcctgac cgagccgacc
     3601 accgagtcca gggcctcgac gctgcatgcc cgcacgatgg agatcctcga ccagcgaggc
     3661 ctgaccgggc ggctgggcga ggtccccggt gacggcacgg gccacttcgg tggcattccg
     3721 cttcggctgg acgggcagca gagcccgtac gccggcctgt ggaaggtccc gcagtcccgg
     3781 gtggaggaga tcctcggcgc atgggcgatc ggcctcgggg ccgaggttcg acgaggccgg
     3841 gaactgaccg gactgcgtga ggacggcgcg gtcgtggagg ccgaactgtc ctgcgaggac
     3901 ggcacgcggg agctgctgcg ggcccgctac gtcgtcgggt gcgacggcga gaacagcacc
     3961 gtccggcggc tggccggttt cgagttcgcc gggagcgccg cgagccggga gctgatccgg
     4021 gccgacgtgg ccgggattga cgtgcccaat cgtcggttcg agcgcctgcc cggcggcctc
     4081 gccatcgcgg cgcgccgccc ggacggcatc accagggtga tggtgcacga gttcggccgg
     4141 acggcgacgc cgaggcaggc ggagccggac ttcgacgaga tggcccggac ctggcagcgc
     4201 gtcaccggcg aggacatcag tcacggcacg ccggtgtgga tcaactcctt cggcgacgcc
     4261 agccgtcagg tgacggagta ccgtcggggc cggatcctgc tggccggcga cgctgcgcac
     4321 gcgcagatgc cagtcggcgg ccaggcgctc aacctcggcc tgcaggacgc gttcaacctg
     4381 ggatggaagc tggccgcaga gatctgcggc tgggctccgc cgggcctgct ggacagctac
     4441 cacgaggaac ggcacgcagt cggctcccgg gtgctgtccg acatcgccgc ccaggccctg
     4501 ctgctgctcg gcgggccgga ggtcgaggcg ctgcgctccg tcgtgggccg actgcttggg
     4561 ctcgacgcgg tccgcgacca tttggccacc ggggtcggcg gcatcggtat ccagtactcc
     4621 gcccacgagg gtgaccaccc gctgttgggg gcgcggttgc ccgacgccgc gctggacatc
     4681 gaggcgggcg cggcaacggc gtgggcgctg ctgcgcgcgg ggacaggtct gctgctggac
     4741 gtggcgcccg aggcgccagg ccatgtggac ctgcgagccg tcgcggacgg ctgggcggac
     4801 cgggtgcgcg tagtggcggc ccggccacgg gcgggcgccg tcgcgccgac gaccggtgcc
     4861 gtgctggtcc gcccggacgg ccacgtggtg tgggccgacg gcggggcgga ccggctgcgg
     4921 gccgcgctgg tgcagtggtt cggctcggcg gaccgcacct gacgagacat tccatttcct
     4981 tggccggacc cggcgcatcg tgcgcagggc caccggccgc atgcgacgag gagaacttct
     5041 gtgaagcgac tggctggcaa gaccgcgctg gtgaccggat caagccgcgg tatcggtcgg
     5101 gcgaccgcgc tgcggctggc gcgcgagggc gcgactgtcg ccgtccacta cgccgacaac
     5161 gccgacgccg ccaaggcgac actggccgcg atcgaggaag agggcggccg cgccttcctg
     5221 gtccgggccg agctgggtgt gccgggtgac gtcgacaccc tcttccaggg tctgaccgca
     5281 ggtctgcgcg aggccaccgg gaaggaggag ctcaacatcc tggtgaacaa cgccggtgtg
     5341 atgggcggcg tgaagcccga ggacctcacc ccggagatct tcgaccggct catcgcggtc
     5401 aacgccaagg ctccgctctt cctgacccag cgcgtgctgt cgatcatgcc ggacggcgga
     5461 cgtatcatca acatcggtac cggactgctg cgttacgcca accccgacga ggtcgcctac
     5521 tcgatgagca agggcgcgct cgaccagatc agcctgcact tcgcccgtct gctcggcccg
     5581 cgcaacatca ccgtcaacac ggtgtcgccc ggcatcacca acaacggcag cccgatcttc
     5641 gacgtccccg aggcgcggga gttcatggcc aacatgaacg ccttcaagcg gatcgccgag
     5701 cccgaggacg tcggcgacgt ggtggccttc ctcgcctccg acgacgcccg ctggatcacc
     5761 ggcaccttcg tcgacgccag cggcggcacg ctgctgggcg gctgaccgcc gtcgggcccg
     5821 gccgatcggc acgggcccgg cacctgcggg tcgaccaccg gtcgtcccgt ccctccgcgc
     5881 ggccgcctag gcgggcccgc atgccttcgt ccctcctgcc cgtcatggga gagccatgtc
     5941 atcagcacgt ctccgtctag ccgttgtcct gggaagcacc cgtgagggcc gcctgtgccc
     6001 gacggtcgcg aactggttcg ccgggcaggg ccgtcaacac ggcggcttcg acctcgatct
     6061 cgtggacccg tacggtctgg acatcccggt cgcaccctcc ccggaaccgc cggcccaggt
     6121 ggtggagatc gggcagcggc tggcggcagc cgatgccttc gtgatcgtca cgcccgagta
     6181 caaccacagc ttctcggcgc cgctgaagtc gctcatcgac tggcactacg tgcagtggcg
     6241 ggccaagccg gtgggcttcg tctcctacgg gggcctggcc ggaggccttc gggcggtcga
     6301 gcaactgcgg ctggtcttcg ccgagttgca cgccgcgacg gtcagggaca ccgtcagctt
     6361 ccacaacgca gcccaactgt tcgacgaagc cggcgatccc cgcgatccgg agggctgcaa
     6421 cacggcggcg aagacgatgc tcgaccagct ccactggtgg ggccgggcgc tgcgccaggc
     6481 tcggctcgaa cgcccctatc agggctgatc cgacgatggc gcggaccgag tccgtccaac
     6541 cggccgaggc ggtgcagctc tggttggtgc gtcccgaacc ggtgcgcccg gatgagctgg
     6601 ccgcgctcga cagcgaggag cggcgccggg ccgaggcctt ccgggggtcc gccgaccgca
     6661 tgctctacct ctcggcccat ctggcgttgc gacgggtgct cgcggcacgg cttggccacg
     6721 tcgcgccgca ggaagtgcgc atcgtccggg accggaacgg ccggccgacc cttcccggcg
     6781 accggccgcc gttccacttc tcgctctccc acagcgccgg acttgccctg ctggggacgg
     6841 caccggtgcg gatcggtgtg gacgttcagc ggacgctttc ccggaccacc gccgatctgt
     6901 gcggtcggcg tctgcatcct gcggagcagg aggagttggc gagcgtgcag ccgtccgcca
     6961 gagcggcgca cttcacccgg ctgtggaccc gcaaggaggc ttacctgaag gggctcggcg
     7021 tcggtctgag ccgttcgctg gccgccgact acctgggggt ggaccgaccc gacaccccgg
     7081 ccgggtggac ggtgctggac gtgccgtgtg gcgagagcca cctggcctcg gccgccgttc
     7141 agagccggtc cccccttcct gtcaccctgc gctggctgct gaggagtgcc gaccatgtct
     7201 gatgtccctt ccatcccggc cgacccggcc ccgaccaccc gctgtcgact ggaggagctg
     7261 cgagcgctta ggcaggcggt ggccgacggc ccggacccga gggcgaccga ggcgcagcac
     7321 gccaagggca agctgacggc tcgggagcgg gtcgagctgc tgctggacgg ggggtcgttc
     7381 cacgaggtgg agccgctgcg ccggcaccgc gcgcagggct tcggcttgga ggccaggaag
     7441 ccccacaccg acggtgtggt ggtcggctgg ggcacggtgc acgggcggac ggtgttcgtg
     7501 tacgcgcacg acttccggat cttcggtggt gcgctgggcg aggcgcacgc gcagaagatc
     7561 cacaagatca tggacatggc catcgcggcg ggtgcaccgc tggtgtcgct gaacgacggt
     7621 gcaggcgccc ggatccagga gggcgtgacc gcgctggccg gctacggcgg gatcttccag
     7681 cgcaacacca gggcctcagg ggtgatcccg cagatctcgg tgatgctggg cccgtgcgcg
     7741 ggcggtgcgg cgtactcgcc cgcgctgacc gacttcgtgt tcatggtccg ggagacctcg
     7801 cagatgttca tcaccggccc ggacgtggtc caggccgtga ccggcgagaa gatctcccag
     7861 aacggcctgg gcggcgcgga cgtgcactcc gcggtctccg gcgtgtcgca cttcgtgtac
     7921 gacgacgagc agagctgcat cgaggaggtc cgctacctgc tgtcgctgct gccgagcaac
     7981 aaccgggaga tgccgcccgt gcagctctcg gacgacccgg tggatcggcg caacgacagc
     8041 ctgctggacc tggtcccggc cgacgggaac cggccgtacg acatgcgcaa ggtgatcgag
     8101 gaggttgtcg actacggcga gtacctcgag gtccacgagc gctgggccac caacgtgctg
     8161 tgcgtgctgg cccggatcga cggccacgtc accgggatca tcgccaacca gccgcagtcc
     8221 ctggctgggg tcctggacat cagcgcctcg gagaaggccg cgcgcttcgt gcagatgtgc
     8281 gacgccttca acatcccgct ggtcaccctg ctggacgtgc ccggcttcct gccgggtgtg
     8341 gaccaggagc acggcgggat catccggcac ggcgccaagc tgctgtacgc gtactgcaac
     8401 gccaccgtgc cgcggatctc gctgatcctg cgcaaggcct acgggggcgc ctacatcgtg
     8461 atggactccc gctcgatcgg tgccgacctc gcctacgcgt ggccgaccaa cgagatcgcg
     8521 gtgatgggcg ccgagggtgc cgcgaacgtc atcttccgcc gcgacatcgc cgccgccgag
     8581 gacccggacg cgatgcgcac ccagaagatc aaggagtaca aggccgagct gatgcacccg
     8641 tactacgcgg ccgaacgcgg cctggtcgac gacgtcatcg accccgccga gacccgccag
     8701 gtgctcacct ccgccctcgc catgctccgc accaagcacg ccgacctgcc cagccgcaag
     8761 cacggcaacc cgccgatgtg accgtgggag cacctatgac atccgacgcc atgaccgatg
     8821 ccatccgggt cgagagcgga cacctcgagc ccgaggagct ggcggcgctc acggtcgtcc
     8881 tgctcgcccg gatccgcggc gcggcgcccg accgcgccgc cggtgacggc ggcagcctcg
     8941 tggcggccac ctggcgccgc ctcgagcgcg ccaacggttt ccagtcgccg agcagttggc
     9001 ggaccgcctg ctgaccgcgc cgcctgtccc tctgtccttg aaggactgac cactcatgca
     9061 ctcaccgttc gaatggaccg tgcggctgcg tcccgcgacc ggctgtcgtt ccagggtcgt
     9121 cgtcttcccg cacgccggtg cggggccgcg gacctacgct cgtctgctgt ccgggctgcc
     9181 cgaggacgtc gagctgatcg gcgtcaccct cccaggtcgc gagcaccgcg ccgacctacc
     9241 gcccggtggc gcgctctgcg aggtcgtcga ggggacaggc cgggagctgg ccgcactccc
     9301 ggtgcttccc accgtctact ggggccacag catgggctcg ctgctggccg tcacggtggc
     9361 cggcacccgc gactgctccg tcgatgccct ggtcctgtcg gcggccctgc cgggtgccga
     9421 tgcggtcgac ttcgcggtgc cgctggacac ccccgagggg ctgagcctga tgttcgaccg
     9481 gcaccggctg cccctgaccg ccctggacgc cgacagcggc cgtccgcgag ccgactttgt
     9541 gctggcccac gacttggtgc tggcgcgcag cgccctgctc gaggtgggcg gtgtccggct
     9601 cggcctgccg ctcagcgtct tcgccggcgc ccacgacccc ctggttccca tgtcgaccct
     9661 gccgaaatgg cgggacttca ccacgggccc gttccgcacc gaggtgttcg agggcgccca
     9721 cttctttccc ttcctcccgg gcaacggccg tgcactcctg gcggagatca cagggctgct
     9781 cacggcagcc gccgagaccc ggagcacgac gagcggagca agccgatgag caccaggcgt
     9841 ccgtaccagg gggcgttcac cccggtcgac caagaggtca ccgccttcga cctgccggtc
     9901 accgggcgga tccccgccga actccgcggc cgctacctgc gtaacggtcc gaaccccttg
     9961 cggctggacg acccgcgcgc ccatctgttc ctcggcgagg gcatggtcca cggcgtccgg
    10021 ctgcgggacg gccgtgccga gtggtaccgc aaccggtggg tccgatccgc cgccgtggcc
    10081 cgctccctcg gtgagaagcc gcgtcgcggc acgcgcttcg cgggcgccga gttcgccccc
    10141 aacacccatg tcatcgggca tgccgggcgg accctggccc tggtcgagaa cgggttccgg
    10201 ccctacgagc tgaccgagga gctcgaaacc gtcggcccgt gcgacttccg gggcactctc
    10261 caggccggct acgtggccca cccaaagctt gacccgcaca ccggggaact ccatgccgtc
    10321 tcctatgcga cccgctggga gttcgtccag tactcggtga tctcgcccac cggcatggtc
    10381 accaggacgg tgaacatccc tgcaccgcac cggccggtga tgcacgactt cgcgctgacc
    10441 gcctcgtacg tcgtcctcta cgacctccct gtggtcaaca gcctggtcgc cgcggccgcc
    10501 ggtgcgccga tggtgtacga ctggcaggag aaccgggggg ccagactggg gctcctgcca
    10561 aggaacggca cggaggtccg ctggttcgac atctccccgt gctgggtctt ccacaccctc
    10621 aacgcgtacg aggacggcga ccgggtggtc gtcgacgtca tccgctatcc ccgaatgttc
    10681 acaggcctgc gactggacgg caactccact cctacgatgg accgttgggt gatcgacacg
    10741 gtgagcggcc gggtcaccga gacccgcctg gacgatcggg cccaggagtt tcccggggtc
    10801 aacccggccg tggtctccgg cccgcaccgc tacggctacg ccgccgtcgt tccggacatg
    10861 cacacctact tcggccccga cgacgacctg gacgacctgc ccgaccaggc gtacagcgac
    10921 gcgctgatca agcacgactt ctccgctggg agctcatcgg tccgccccct cgggcgcggc
    10981 cactacaccg gcgagccggt cttcgtcgcc accgcgtccc cggcggcgga ggacgacggc
    11041 tacctgttgg cctacgtcca cgaccccgac cggggcgcga gcgatctggt cattctgtcc
    11101 gcccaggact tcaccggcga acccgtggcc accgtgcacc tgcccgcgcg ggtcccgctc
    11161 ggcctgcacg ggagctggat cgccgatccg gcctgactga acggtaggtt ccatgcaccc
    11221 cgtacccgct ccggaacagc ctggagaact gatcgcccgg ctccgggccg cgagccgaac
    11281 cggccgcccg cggtccctgg agtggcggac cgagcaactg acccgactgc gctccctgtt
    11341 gcaggagcac acggacgcgc tcgcggaagc ccttttcgcg gacctgcaca agagcaggtc
    11401 cgaggcccat gcggctgaga tcgggttcac ggtccgcgag atcgaccacc tgttggagaa
    11461 cctggaggag tggctccggc cgcagccggc ggccgtgccc ggctgcccgg cgggctcgac
    11521 ggcgtacgtc cagtacgacc cgttgggcgt cgtgctcgtg attgccccgt ggaactaccc
    11581 ggtgcagctg ctgctcgttc ccgtcgccgg cgcgctggcc gccgggaaca cggtcgtggc
    11641 caagccgagt gaggtggccc cggcttgttc ggcgctgctc gcccggctga tcccgcagta
    11701 tctctcccgg gacgccgtcg ccgtagtcga ggggggcgtc gcggagacga ccgccctgct
    11761 ggcgcagcgc ttcgaccaca tcttctacac cggcaacggg actgtcggcc ggatcgtgat
    11821 gcgcgccgcg gccgagcacc tgactccggt caccctggag ctcggcggca agtcaccggt
    11881 gttcgtcgac cgcggaacga atctcgcgga tacggcgacc cggctggccc gggccaagtt
    11941 cgccaacgcc ggccagacct gtgtagcccc cgactacgtg ctgaccgacc ctgatacggc
    12001 gcggggcctc gtggcggaga tcgcccggtc cgtccggagg atgttcggct ccgaaccgga
    12061 gctggcgcgc gggtatgggc ggatcgtcaa cctgcaccac ttcgaccggg tcgtccgcct
    12121 gctcggctcg ggacggatcg ttctcggcgg ccggcatgac cgcgagaacc ggtacatcgc
    12181 cccgacggtc ctcgcggacg tggcggccga gtcgccggtg atgcgggagg agatcttcgg
    12241 cccggtgctg ccgatagtcg aggtgcccgg agtcgaccag gcgatctcgt tcatcaacga
    12301 ccgggacaag cccctcgcgg tgtacggctt caccgcacgc gaggaggtcc ggcgcaggct
    12361 cgccgaggag acgacctcgg gaggcctggt actcggcatg ccgatggccc aggtcctgga
    12421 ccccgggctg cccttcggcg gtgtggggga gagcggtacg ggcagctacc gcggtgccca
    12481 ctccctcgcc gccttcagcc acctcaagcc agtgctggac gttccgatgc ggccgaccgg
    12541 cccggtgggc tgaggcggtc gaggctggca ccgatgctgt ccagtagtcg ctcgagaccg
    12601 gaccggaaac gctggtcggg ccccatgtgc ggggccacgg tctcggcgag cacccgcgcg
    12661 aacatcgggt actcgccact gtcgacgagt tgctgggcgt agggcccgct ccgccgcatc
    12721 cattcccgca tgtccacctt ggtgcggcgc gcctcctcca gccagccgac ctcgttgcgg
    12781 acgaagctct cgacgtagcc gttgtagagg ccgatcaggc tgagcagttc gtcgacctgg
    12841 aggtcgaaga cgccgagcgt gccgagcacg aactcctgct ggcgcaatga gttcggcccc
    12901 cagaccgggt ggccgttcct ccaggccgtg gccagccacg ggtggcgcag ccacagggcg
    12961 cgtttctcgt tggcggccag ggtcaacgcg gcccgccagt cagggcctgg ccggtccggg
    13021 agccgggtct cgccgatgac ctcgtcgacc atcagctcga cgaggtcctc tttggtgggg
    13081 acgtagtagt agagggacat cgtgccggcg ccgagttcgg ccgcgacccg gcgcatcgac
    13141 gccgcctcga caccctcggt gtcggccacc ttgacggccg cccgaacgat ctggtcacgg
    13201 ctcagcgtcc ggtgcgaccg cgccgaccgc cggccggcgg gctccgggtg catccagatg
    13261 ctgacgggtt cgttctcgtt catccacact ccccagctgc tctggcgtac accgtaccaa
    13321 ttgcgctacg ctccttcttc gtacggtgta tgaatacgac gcgccagtcc gaggaagtgg
    13381 tggtcatgcc agatgaggat gccgttgcgg tcgaagcccg tccggaggct ccgcgcaggc
    13441 cggcgccgag gtaccgcggc ctcggggtgc tggccgtact gctcggcctg gcgctgtcca
    13501 tgctggacca ggtgatcgtc ggtacggcgc tgccgacgat cgtcggagag ctcggtggac
    13561 ttgacgaact gtcctgggtc gtcaccgcct acatggtggc cagcgccgct gtgatcccga
    13621 tctggggcaa gttgagcgac ctctacggcc gccgcggcac gtacatcacc gccctcgtca
    13681 tcttcctggc cggctccgtg ctcgcgggta tggcgcagaa catgacggag atcatcgtct
    13741 tccgcgcgct gcagggtctc ggctccgccg gcctgatggt cggtacgttc acgctgatcg
    13801 gcgtcctggc gaccggcccg gccgaccgga ttcggatgca gaccatgatc ggcatcgtca
    13861 tgccggtcgc gctgggggcc gggccgctgt tgggcggcct gctcaccgaa cacgtcggct
    13921 ggcgctggtc gttcttcatc aacgtcccgc tgtgcctggt cgcgctggtg gcgagcgcgc
    13981 tgggcatccc gcgcagcccc cggcgcgaga aggtccgtat cgacgtcctc ggcagtgtgc
    14041 agctcaccgg cggagtcgtg gcgctcaccc tgctgctgag ctgggcgggc acgcgctacg
    14101 actggatctc ggcgccgatc ctcggcctgg ccgcggtcag cgccgcgctg ctcgccaccc
    14161 tggcgctgac ccagcgccgg gccgtggaac cgatcctgcc gtcccggctg ttccgcacca
    14221 gggacttcac gctcgcccag gtggtgggtc tgctggtagg agccggcctg ctgggcgtcc
    14281 tggtgtactt cccgcagtac ctgcagcagg tcctgggcgt cacgcccact tccagcggac
    14341 tgctgctgct gccgttcctg atcggaatga tcgtcatgga gctggccgtc gcccgacggg
    14401 tcgtcaagac cggtccgctc cccgtctacc cgattgccgg tggcgtggtc gcggtggtcg
    14461 gtgcgctcgc catgctggcg ctcggtaccg gtaccagcgt cctcgccgcg gcgctgatcc
    14521 cgctggcggc cgggctcggc atcggggtgc tgatgcagag ctcgctgatc atctccttcg
    14581 cctgccagac cgaccagcgc gacctggggg cggccagcgg cgtgctcaac ctgttccgta
    14641 cgatcggcgg ctcgctcggc gtcgcggtgc tcggttcgct cttcagcgcc cgggtcgagc
    14701 acgtgctcac agagcggatc ggcgcccacg ccgggcgctc gctcgccgcg gccagcggtc
    14761 ggagcacccc ggccgacatc cgcgccctgc cggcgccggt ccgcgacgcc ttccagtccg
    14821 ccgtggtggg agggctgcac agcgtggtca tcggcatggt ggtgattggc gtgctggccc
    14881 tggcgacctc gttcttcttc cgccggctga atattccggg gccgttcggt cagggcccgg
    14941 gcccgcgccc tgacgggaat accgtgtcgt cggctcggaa tgccggatag ctagtggagc
    15001 gctaagtcga attagcgggc tactagaact gcgatgcttg ttcgccgggt acccggtccc
    15061 tacgatcgaa tccattccgg cgaccgaggg ctccggactg gaattcagtg cggcgggcga
    15121 cacgcggcgt ccgccgctgc agttcgtcag caaaccatgc gaagcggatg tggaacggac
    15181 cgtcatccgg cgcatcggac gatgttctgt gagggggcgg ggcaggtgac aacacggggc
    15241 agcctggtgg gcatcagcga cctgcacgtc cactacgagg acaaccggag ggttgtcgag
    15301 cggctgcgcc ccgagtcggc cgacgactgg ttgctgctcg ccggggacgt cgccgagacc
    15361 gtcgaggaca tcgcgtgggc catggacctg ctccgcggac gcttcgcgaa ggtggtgtgg
    15421 gccccgggca atcacgagct gtggaccccg ccgtacgacc aggtgcagct gcgcggcgag
    15481 gcccgctacc ggcacctcgt cgagctctgc cgggggctcg gcgtggtcac ccccgaggac
    15541 ccgtacccgg tctgggacgg gcccggcggc ccggtggcga tcgcaccgct cttcgtgctc
    15601 tacgactaca gcttccgatc cgacggtgcc cgggatgagc aggacgccct ggcgctcgcc
    15661 gaggacgccg gggtgatctg cacggacgag ttcatgttgc acgccgaccc gttcccgagc
    15721 cgtgcggact ggtgccgcgc cagggtcgag tacaccgagg cgcggttggc tgccgtcgac
    15781 gaggcgctgc cgaccgtgct ggtcaaccac tatccgctgg ttcggacgcc cacccgggtg
    15841 ctccgccatc cggagttcgc gctctggtgc ggtaccgagg ccacggcgga ctggcaccga
    15901 cggttccgcg cggccgctgt cgtctacggc cacctgcaca tcccttcgct cctgtacgag
    15961 gacggtgtgc cgcaccacga ggtctccctc ggttacccga gcgagtggca gcgccgcccc
    16021 gccgccccgg gccgcctggt gcggattctt ccggagccgg ccgccaccgg gagccgggcg
    16081 tgatcgaaca cgtgctgtcg cggccggtcg tagccgtcga cactttcacc gatccggtgg
    16141 aaccgccggt gctcttccgt gaggaggagg agctgatcgc gcgggcggtg gacgcccggc
    16201 gcagcgagtt cggcaccgta cgcgcctgtg cccgcgctgc cctggcagtg ctcggtatcg
    16261 atgcggtgcc catcttgcgc gggccgtgcg gcgagccggt gtggcccgcg ggagtcgtcg
    16321 gctccatgac gcactgtgag ggctaccggg cagccgccgt cgcacgcgag ggcgagctgg
    16381 cggccgtggg catcgacgcc gagccccatc ggccgctccc gggcgacgaa ctggacgtga
    16441 tcgctcgtcc cgaggagctc ggcccgctgt ccggactgcg ggtccggtgg ccggagatct
    16501 gttgggaccg gctgttgttc agtgccaagg agagcgtgta caaggcctgg ttcccgctca
    16561 ccgggcgatg gctgggcttc gaggaggcgc tgatcgactt cgacccggag gccggctcct
    16621 tccgggcccg gctgctggtt ccggggccga ccgtcggggg ccgccggctg ccgggcttcg
    16681 acggtcactg gctggcccgg gacgggctcc tgctgacggc ggtcgcagta ccctccgact
    16741 gaatagcgga gatttagtaa aagcttagtc gatgtccgct tgagttcttt cctgaattcg
    16801 acgatgctgc ttttgcgttg gcggagagaa ttcgtttgcc atcgtcacgg atatagcgac
    16861 ttcggtcaat tcaaggaggt ttcgcatatg gctcctgtcg cgattgtggc cggcgctgtc
    16921 cgtggtacgg ggtctgttgt cgcagtgcgg ctggcggagg ccggctggga tgtcgcggtg
    16981 ctctgcgccg acggtgccgg gaacgcggac accgtgcaca gggtgcgggc ggtcggccga
    17041 cgggcgctgg cggtcgagac cgacgtcacc gatgcggtgt cggtccaggc ggctctcgac
    17101 cgggtgtgcg ctgaactcgg cgatccgggc gttctggtga acagcgtcgg ggtgatcgcc
    17161 tgcggcgcgc cgggggaggc ctccgaggag gactggaacg cggtggtcgg ccgttcgctg
    17221 cgagggttgt tcgtcaccag ccgggcggtc accgatctga tgatcaggca gggtcgaggt
    17281 cgcatcgtca ccatcgccaa cctgctgggt cccgccgagg gcgggccaca cgatcacgcg
    17341 acggttctgg ccggcatggc gggcttcacc aggacggtcg cactcgagct gcgcgccttc
    17401 gacatcacgg tgaacgccgt cgcgccggca cctcccgtcg tcggcatgca ggcgccggcg
    17461 gccccgaccg cagcggaccc ggaaggttcg cggtgcgcga cgcaggctgc cgaggcagtg
    17521 ctgttcctgg tcggtggcgg ggcgtcatcg gtgaccggtc agaccgtcca ggtgggcgac
    17581 gaggaagcgg ccgcctgaac acccgttctc gtcagctgaa ttggaggatg tgacttggaa
    17641 ggcaacgagc actacgtccg gcagatcctg aacaccctcc gcgccgaccc ctccggcgtg
    17701 gcgctggtgc atcgggacac gcccgtgatt gccggcgacc tggctgactc gatcacgtcg
    17761 gcggcggagg cgatgcgcgg aagcggtgtc ggcgtcggga gcgtggtcgg gatcctgacc
    17821 gaccccaaca cgcccgcgac cctggtggca cgctatgccg ccaacctgct cggtgcgacc
    17881 gtggtccacc tcttcggtgt caacgccgcc aacccgtccg acctgctctc ggcggaggcg
    17941 cagggcggca tcgtcgctga agcgttgccg gcaatggtgg tcgtggacgc ggccaacctc
    18001 gagcgcgcgc gggcgatccg cgaggtgccg tccgtccgcc cggtgctctc cggattgggc
    18061 gaactcggcc acgacgtcat cgacctgacg gacagtccgg caggcgcctt ccgccctgac
    18121 gcggcgcgcg acggtgacac cgccgtggtc accttctcca gcggttccac cggtcggccc
    18181 aagggaacgg cctggtcatt cagggtgaag gccgacatgg tcgcggcctc cgcgcgccgt
    18241 gcccagaagg cgaccgccct ggtcaccgcg cccctgacgc actcgaacgg cttcgtcgcg
    18301 gacgacgtgc tggtctccgg tggaacggtc gtgctgttgc ccggcttcga cgagaccgag
    18361 gtcctgcgca gcgtggcccg ataccaggtc aaccggctgg cggtgtccgc tccccagctg
    18421 tacgcgctgg ccgaccaccc agagaccacc cggaccgatc tgtcgagcgt gcgcgacctc
    18481 ttctacaccg gggtcgcagc ctcgccggag cgcgtcgcgg tggccgagaa ggtcttcggc
    18541 tcggtgctca tgcaggtcta cggcacgagc gagaccaaca tcatcagctg gctcatcgcg
    18601 ggcgagcaca cggacgccgg cctgcgcgcc acggtggggc gtcccctcga atggcttcgg
    18661 gtgaccatcc gcgaccccca ggacgagcgg gtgctgccga ccggcgagac cggtgaggtg
    18721 tgggtcaact cgccgtggcg aatggaccat tactggaacg acccggagca gaccgcgcgc
    18781 accgtccggg acgggtggat ccgcaccggg gacgtcggac acctcgacga cgcgggttac
    18841 ctgcacttgc acggccggct cgcgggcgtg atcaagacca acggcatcaa ggtctacccg
    18901 gtcgcggtcg agcgttcgct gctggaccac ccggacgtcg ccgaggcggc cgtgttcggg
    18961 gtggagaaca gcgaccgggt cgagcggatc catgcggtgg tcgtgctgcg cgagggcgcc
    19021 ggggccggcc ccgaggacct ccgacagcac gtgagctccc acctgtcccc caaccacgct
    19081 ccggccgaca tcgagctgcg gtccagcctc ccgctcatcg gcttcggcaa gccggacaag
    19141 ctgcggctgc gcgcggacgc gatggcgcgt cgggaggcca cccatggcga atgagagtcc
    19201 tgtgatgacc ttggagaaca acatggccat gccatccggc agtgtggtgt cggtggttga
    19261 ggtcgagggc ctcgtcgact cggtggtctt cgcggccgcc gtcgacgtcc tgctcaagcg
    19321 ccatcccgcg cctacggcgg ggctgtcctg gcgcgaggtc gaccggagcg gtccggacca
    19381 ggacagccgc aggaccgggc tggaccggct cgcgaccgag gacggagaag cggtagtcgt
    19441 cggcgccccg ccccggctga cgctggtgcg actgcgagcc gacgccttcc agcttcggct
    19501 cgcaagtgac cgtgccgtcc tggacgcccc gtcccaccgg gtgctgctcg gcgagctgct
    19561 cgaagagtgt gccgcgccgg ccggggcggt gggccccgcg cccgtcgagg accgcgtcgc
    19621 gtggacggcg gaaggggagc gcggcgaggc cgagcgcgcg tggcgcatcc ggctcgcgga
    19681 ggtggacgaa cccaccctgg tggcaccggc gggatcggcc gggtattcac agcgcccgga
    19741 gcgggtcgag agcgagctgc ccacggacct ggccgagcgc ctgctcgtcc gcacggacga
    19801 ccgccggctg tcgctcgaca ccatcgtgca cgccgcgtgg ggcctggtgt tgagctggct
    19861 gaccaaccgt cgcaacgtcg tcttcggcgg cctccgttcg gaccggtccc ggtttcctgt
    19921 ggcagagacg gcggtgggcg gcttctccga gatcgtgccg gtgccctgcg cggtgaaccc
    19981 ggcggagccg atcgcggacc tgctctcccg caccgagctg gacggcaccc tgatcgcgga
    20041 gcacagcgcc ctcggcgcgg cggagatcca cgccctcgtc ggcctgccgc ggctgttcga
    20101 caccgtcgcc gtcgtggagg acgccggcct cgacccggtc ccggcgccgg agggcctgcc
    20161 cgggctgcgg gttgtcgccc aggagcagtg ggaggacttc ggcagcgcgc ttgcgctggt
    20221 cgtgcgccgg tccgagggtg gactgcggct gaacctggac tttcggccgg agctgttcac
    20281 tcaggccgac gcggagcgga tcctggcggc gttcagccgg accttccgga cgatcgccga
    20341 cgagccgaac cagcccgtcg gccgggtgca gctgctcgac gaccacgagc agcgcaggat
    20401 cctggccgac tcggacgcca ccgccgacgg ggttcccgcg gtcacgctgg tggagctgct
    20461 ggagcagacg gtcgcgcgga cccccggcaa cacggtggtg tctttcagcg gccagcacat
    20521 ctcctacgac gagctgaatc gtcgcgtcaa ccggcttgcc cggctcctgg ccgatcgggg
    20581 cgccggcccg gagcaactgg tcgcgctggt cgtgccccgg tcgatcgaga tggtgaccgc
    20641 ggtactcgcg gtggccaaga cgggcgccgg attccttccg atcgaccccg gctaccccgc
    20701 ggaccgcatc gcctacatgc tcggcgacgc cggccccgcg gtggtgtgca ccactcggac
    20761 ggccgcggcc gtgctgccgc aggacgtcag cgggatcgtc ctcgacgatc cggcggtcgc
    20821 cgccgaggcg gccggcttgt ccgacgagga tccggtggcc tccgagcact gggctccggt
    20881 gccgcctgcc gcgctggcct atgtcattta cacctccgga tcgaccgggc ggcccaaggg
    20941 cgtggccgtc acgcacgccg gtctcgccaa cctggtggcg gccaaggtcg agcgaatgga
    21001 cgtcgacgag cagagccgga tcttgcagtt cgcgtcgccc agcttcgatg ccttcatgac
    21061 cgagttgctg gcgaccatcg gggccggtgc cacgctggtc gttccaccgc ccgggatcct
    21121 cgccggggac cacctcgctg aggtcctcgt cgcggagcgc atcacccacg tggtgcttcc
    21181 gccggttgcc gcagcgagcg tgtctcccga aagtctgccg gacctgcgct ccctggtcct
    21241 ggccggcgag gcgtcctccg gggacctcat agcgcgctgg gcgcccggcc gccgcgtgat
    21301 caacgcttac ggcccgaccg aggcgaccgt ctgcgccacc atgagcgaac cgctctcggc
    21361 tgatgcgacg ccgccgattg gcggaccgat ccccggtgca gcctgctacg tccttgatga
    21421 ggccttgcgc ccggtgcctg cgggggtgcc cggtgagctg tacctcggcg gcgccggcct
    21481 cgcccgcggc tacctcgggc gaccggggat gacggccgag aggttcgtcg ccaacccgtt
    21541 cgccggcgac gggtcccgca tgtaccggac gggtgacctg gtgtcctggc ggtcagacgg
    21601 tggtcttgac ttcctcggcc gctcggatga gcaggtgaag ctccgcgggt tccggatcga
    21661 gctcggtgag gtggaacggg tcctgacaaa ccacccgggt gtcgaccgcg cggtcgccgt
    21721 ggtccgggag gacggggccg gcggtcgtcg gatcgtggtc cacctgatcc cctcggcggg
    21781 cgccgcaccg accatggcgg agctgcgtga acacgccggg cgcttcctgc ccgacttcat
    21841 ggttccgggc gccttcgtcc tgctcgacgc cttcccactt acgccgaacg gcaagctcga
    21901 ccgccgtgcg ctgcccgagc cggacgcggc gccggcgccg agcgggcgag cacccagtac
    21961 cccggaggag atcgccctga gcaggatctt cagtgaggtg ctcggggtgg ccgaggtgga
    22021 cgccgaccgg aacttcttcg agctcggagg caacagcatg gtggccatca ccgtgatcca
    22081 gaaggcccgg aaggcgggcc tggcgatctc gccgaaggac ctcgtcatga acccgaccgt
    22141 ggaggcactt gcagcgatag cgggccgtac cgaccaggcg ccgaggcgcg ccgaggccac
    22201 aacggccgtg aagtgaaggg gacgatgatg aacccgcgac cgatgctctc gccggacgtc
    22261 ctcgaggaca tcgacctcaa cgaccggcaa ctgcacgcgg actacgacct cagcgaggtc
    22321 tggcgctacc tgcgggccga gcgtcccttc tactaccaga ccgcgcgcgg atcccagccc
    22381 ggcttctggg tggtcacccg gcacgccgac tgtacggcgg tctacaagga caagacgaac
    22441 ttcaccgcgg agcggggcaa cgtgctgccg acgctgctcg ccgggggtga ctcggcgtcc
    22501 cggacgatgc tcgcgctgac cgacggcgac cgccacaccc aggtacgcaa cctgctgatg
    22561 aaggcgttct cgcccaagat gctgagcaac atcgggcaat cgcttcgcac caccgttgac
    22621 ggactgttgc gggacgccat cgagaagggc gagtgcgact tcgcgcgcga tgtctccggc
    22681 aaggtcccgt tggtcgcgat ctgcgatctg ctggcggtgc cgcaggagga ccgcgagtac
    22741 ctgctcagcc ttaccgcgca cgcactgagc gccgacgagg ccgacgccac ggcagaggac
    22801 aactggaccg cgaagaacga gatcctgctg tacttcgcag acctcgccga gagccgccgg
    22861 tccagcgggc acaacgacgt ggtcagcctt ctggcgacca gcagcatcga gggcgagccg
    22921 ctctccgacg gcgagctgat ggccaactgc tacggcctga tgattggcgg cgacgagacc
    22981 ggccggcacg cgatcaccgg cggtctgcgc gccctgatcc atcacccgga ccagtggcgg
    23041 atgctccgca acggtgaggc agatctccag accgccaccg aggaggtgct gcggtggact
    23101 gtgccctcgc tgcacggtgc ccgcaccgca accgccgacg tcgtggtcaa cggcaagcag
    23161 cagatccggg ccggtgagat cgtcagcgtc tggttcgcct cggccaaccg ggacgaggag
    23221 gtgttccgcg acgcggaccg attcgatctg aaccggaccc ccaacaagca cctcaccttt
    23281 gccttcggcc cgcacttctg ccttggccac tacctggcgc gcatggaggt ggaggcgatc
    23341 ctcgacggcc tgcggcggat ggtcgacgac atccagcaga ccggtccgga gaagctgatc
    23401 tactccagca tcctgcaggg aatcagttcg ttccccgctc tcctcaagcc cgatcgccgc
    23461 gtcccgccgc agacctgacg aaccatccgg attttgcctc agaaaggtaa tgccatggcc
    23521 aacccgtttg acgaccaacg cgggagcttt ctggtgctgc gcaacgccga ggagcaggtc
    23581 tcgctctggc cggcattcgc cggtgtgccg accggatggc aggtcgccaa ggggccgaac
    23641 agccgggcag cgtgcctggc gtacatcgag gaggcgtgga ccgacctgcg cccgaagagc
    23701 ctgatcgacg cgacggaccc cagctgaggc ccgtcttgtg aatcagccct ggcccgcgac
    23761 ccgggcagac cgaccgaaca tttgcaggga aggagcacga atgagcctcg gggccgacac
    23821 cgtcgcgatc gtcaccggag ccggacgggg catcggcgcc gccacggcgc agcggctcgc
    23881 cgcggagggc gcgaccgtgg cagtcgtcga ccggaccgag gcggacacgg ccgacaccgt
    23941 ggcgtcgatc cgggcggccg gtggccgcgc cctcggcatc gggtgcgacg tgacagtcac
    24001 cgacctggtc gaggcggcgg tcgaccgcac ggtcgcggag ttcggtcgtc tggacgtcct
    24061 cgtcaacaac gccggggtaa cccgggacag cctcgtcttc atgatgggcg acgaggactg
    24121 ggatacggtc atcgacgtgc acctgaacgg cgccgcccgg accgtccgcg cggcacggcg
    24181 ccagatggtg cgtcaaggtt ccgggcggat agtgaacttg agctcgatcg cggctctggg
    24241 caaccagggg caggccaact acgccactgc caaggccgcg atccagggct acacccgcac
    24301 cctggccgtg gaacttggcc cgcacggtat tacggtcaat gcgatcgcgc ctgggttcat
    24361 cgccacgacc atgacggacg acacggctcg ccggatgggc tccgatccgg tggcgctgcg
    24421 gaaggcggtg gcgtcgcggg tgccgatgcg cagggttggc aggccggagg acatcgccgg
    24481 cctggtggcc ttcctggccg ggcctgatgc gagctatctc acagggcaga cgatctacgt
    24541 cgacggcgga ccgcagtgaa ccccccgctc ctcggttcgc cgcctggctg cattgtggca
    24601 aacgctcaat cccgcatgaa tccgactcag gtgctcctgt caagtcttct aacccgccga
    24661 gtcgttgaca cgacctagat cggctgtagg ctacctgtat ccagggcggg cacttgtgca
    24721 ctggccatgt gcgagagcgg ccgtcgaaac tgacgagcgg gggctcagtg gtgcagattc
    24781 ttacggtgac tgatgatctg caattcttcg aggagttagc agacgatctg ccgaaccgcg
    24841 gattccaggc cagacgggag gatggtatcg gcggcgcact gaccaagtgt cggagcgttg
    24901 atgtaatact ggtcgatctc gccatatcgg agaccgacgg attcgaggta tgccgtgcaa
    24961 tccgggcggt ctcgcatgtg ccgatcattg tcgtgagtgc gcgggatgac gagctcgatc
    25021 agattctgag tctcaaattg ggagccgacg actatatcgt gtggccgtgc ggcatgcgcc
    25081 agttggtggc ccggatggag gcgctcattc ggcgtgccag aaatgcctgg gagtcctggg
    25141 gtgttccgtt ggcgtcggcc gaggccggag ttcgccaatt tggcccggtc cgtatcgatc
    25201 tacagcgccg gtcagtgacc cgggacggcc atgaggtccc gctgacccgc aaggagttcg
    25261 acatgctggc gctgctggcg accgaccccg gccgagtgtt cacccgtgag cagatcatgt
    25321 tcgaggtgtg ggggcatgac ggagccgggg acactcggac tctcggcgtg cacgtgacgg
    25381 gcatccgcaa gaagctgcgg atgccggagc tggtcgagac ggtccgcggc gtcggattcc
    25441 ggctggccaa ccacacgttg tcggaggatc aggcagcggc ctgagcgatt gctgccgctt
    25501 tgtgcgacgt gcctcgcccg aggcgcgtcg cacggtgttt tggcctgccg cgagggcgtc
    25561 gtcagccttc tccggtccgg gcgcacgggc ctagctggtc gtggccccgc cctgcacctc
    25621 gtccgggagg tggttccggg ccggcctcgc caggcctgtc cactggaacc ttgccagaac
    25681 ctaacgaaaa cctagaatct ctctgcttgt acttcaccat aattacagcc aagctattgc
    25741 gtgatgtccg gcgatcagta atgccagccg gatcgaccgg gaatgacgat atccggagtt
    25801 gcgtgatggt tcacaatggc cggggtgtcg ccctggtgac cggcggatcg cgcggtattg
    25861 gtcgcgcagt cgtcctgcgg cttgttcgcg agggattcga tgtggcgttc tgctatcagc
    25921 gcgaagccgt ggccgcagcc gatctggaga aggctgtggc cgaattgggt ggccgcgtcg
    25981 cgcaccgacg ggtggacgtt tccgatgccg ttcaggtcaa ggaatgggtg cgtgacgtag
    26041 agagcgaact cgggcctgtc gaggtcgtgg tgacttccgc cggaattgtg cgggacgggc
    26101 ccctcgtcat gatgcaggac aaggactggc aggacgtcat cgacgtcaat ctcaacggca
    26161 cgttcaacgt ctgccgggcc gctgtcttcg gcatgatgaa gcgcaaatcc ggatgcctca
    26221 tcaacctttc ctcggtggcc ggcgtgagcg gtcatgccac ccagtcgaac tattctgcct
    26281 cgaaggccgg gatcatcgga ttcacgaagt ccctctcgaa ggaactcggc cgatacggaa
    26341 tccgggccaa tgtggtggcg ccggggttca tcgacacaga tatggtcgcc gggatttccg
    26401 acgggctgcg gaccaaggcc gtcgcaggcg ttgcactcgg ccgtttcggc cgacccgacg
    26461 aggtggcgga cgcggttgcc tacctggcgt cggcggagta cgtcaccggc gcggtgcttc
    26521 agatcgacgg cggcctttcg atctgacggt ctgacccggc ctgccgcggg ccgacctgtt
    26581 cagcgggccg tcaccacaca gggagtactg gcatgagccc cactatgaca ctccgcccgg
    26641 agcgcgttga gccggccgtc gtcggcgcgg gtcgccgctt cacgaggtcg gcgtccctca
    26701 tcgactccac ggtgacaccg aaccacgtct tcgaccggtg gttcgccgag cagcggatac
    26761 gcaaccggtt cgaggtcgac cgcatcccct tcaaccggct gcggagctgg cgcttccacc
    26821 cggagaccgg gaacctgggg cacgacagcg gccgcttctt caccgtcgag ggcctccacg
    26881 tcgagaccaa ctggggccac cacccgtcct ggacgcagcc gatcatcaac cagcccgaga
    26941 tcgggatcct cgggatcgtg gtcaaggagt tcgacggtgt cctgcactgc ctgatgcagg
    27001 ccaagatgga gcctgggaac ctcaacacca tccagctctc gcccacagtc caggcgaccc
    27061 gcagcaactt caccggtgtc cacggcggac gcgggatcac cttcatcgag tacttcaggg
    27121 acaccgagcg cagccgggtg cttgtcgact cgctgcagtc cgaacaggcg tcgtggtttc
    27181 tgcgcaagcg caaccggaac atgatcgtcg aggtgaccga ggacatccca ccgcacgagg
    27241 acttcgtctg gctgaccatc gggcagatcc accggctctt gctccaggac aacgtcgtca
    27301 acatggacgc ccggacggtg atgtcctgca ttccgttcga cgcgcccaac ggcggctccc
    27361 ggtgggacgc gccgcgcgac ttccgggaga gcttggtggc ctcgatgtcg ggggagcaca
    27421 ggtccctgca cagcaccggc gagatcctga gctggctgac cgacctccgg acccggcacg
    27481 cgctgatcca gcgcagtgtg ccgctcaagg acgtcgagca ctggcaggtc ggggccgagg
    27541 agatcgccca cgagacgggg aagtacttct ccatcatcgc ggtcgacgtc caggccccca
    27601 accgggaggt cgccagctgg acccagcccc tgctcgcccc ggtcgagtgc ggccgggtcg
    27661 cgatgatcgt ccggcggatc ggcggagtgc tgcacctgct gctccgggcc cggctggagg
    27721 ccggggtgct caacgtggcg gagatcggcc cgacggttca gtgcctccca ggcaactacc
    27781 gcgacgtgcc ggaggaggag cggccgccct acctcgacct ggtgctggcg gccggcccgg
    27841 agctgctgcg ctacgacgcc gtgcagtcgg aggagggcgg gcggttctac caggccgaca
    27901 accgctacca gatcatcgag gtgggcgagg agttcgacat cgacgtcgcg cccggattcc
    27961 ggtggatgac tgtggagcag gtgacccgtc tgctgtcgca cagcaactac ctgaacatcc
    28021 aggcccggag catgctgacc ggcctgcaca ccagctggtg acccacggcc ggacagcggc
    28081 ccgggtctgc ggaacgggag gacatgtgag cactcgggtg cggctccgtg aaggacggat
    28141 gatcacctcg gacacggccc cggggaccgt cgtccggtgt gattcgtccg agacgatgta
    28201 cctggcgcgg tacgtgtcgg tggccttttt cttcgagcga accctggaca ccctgcgcct
    28261 ggcagacggg ctgcgcggcg cgctcgctct cgtgccggcc ttcgcgggtc ggctgcgggc
    28321 cggcgacggc gggttggaga tcgtgtgctc cgacgccggc gtgccgctgt cggtcctcga
    28381 cgttgacgcg accctcgacg aggccaggac ggacgtgacc cgccccgact cgatgctcat
    28441 cgaccgggtc gacgtccgga ccggaagcct ggcagagcgt ccgcttctga cggtacgggt
    28501 ctgccggacc accgacggcg gtgcgacgct ggggtgcagc tggaaccacg ccgtgggcga
    28561 catgagcagc ttcatgcagt tcgtccgcgc ctgggcggcg cttgtcggcg gaacggcgcc
    28621 gccggagatc cgtgtgctcg acgaccggat ggcctatctg gaccaggtcc tgccggacga
    28681 gggcatcgca cagccggggt gcgagccgct ggaccgggac gcgatggcgg gacgggggcc
    28741 cgaactgccg cctgcgctgc cggacaacgc cgccgtgcag ctctactttg gcgccgatga
    28801 ggtgctccgg atgcggaagt cgttcggcga ggccgcctcg cgacgggtgt cggtgaacga
    28861 cgcaatctgc gcccacctgg tggccacgct acgggacagc gaggcagagc ccacctcatg
    28921 gaacctctcg gtgtccgtcg acttgcgcca ccacctcggc ctgccgaggt cggtgatcgg
    28981 caatctcgtc cagtccctgt acgtgccatg cccgcagacc ggcgccgggg agctgtcggg
    29041 tcacatccgg gcggggctgg acgacttcat acggtcgcac cagtgcctga gggccgaccg
    29101 cgcattcatc ggccccgtcg ggcggtcccg gttccatcac tgcgctccgg tgcccttcga
    29161 cccggggcac aggacgttca tcctgacgaa ctggacccgc atgggcgtgt acgacgtcga
    29221 gttcgaagga cagcgcccga ccttcttcag cccgatcgtc agctcccacg cgccgttcac
    29281 ctggttcgcc atggtggccg agggcccctg gaacgagggg ttcctggtta ccgcggtgct
    29341 cccggcgaag gccgcggaac agctgcggag cccggagggt cgggcagcgc tgcaccgctt
    29401 cgccgcgacg gacgacccct gctcgtgggg tccccaccga caagtcaccc atggctgaac
    29461 ttgaccacgg cacccctgcc tttcgtgcca tcgccgcggg caacgggcat gtcgtcgggc
    29521 ccatcgtgcg tgacgagtgt gcggcgcccc cggcaccgcg cgccgaggtg gacgagaact
    29581 cgaggccatg cggcgcctcg cgctgctcgg ctgcaccacg gtgaccgaac ccgacgtgcc
    29641 ggtgccgttc gacatcctcc aacgcccctt cgccgactcg aacgccttcg ttcgtgcggc
    29701 cgcggcggcg tccaaggccg tcgcaccggt cgtcaacggc gccgaggcag tggcgaggtc
    29761 agtggcattg acagtcgctg aagctcacgt gagccgcgaa cacagcgcgg cctgaaggat
    29821 caatgcgaga ggagaaacaa gtgaggggca tcattctcgc cggtggcaac ggcactcgtc
    29881 tggcgccgat gaccagcgtc gtctccaagc agttgctgcc ggtctatggc aagccgatga
    29941 tctactaccc gttgtcggtg cttctttcgg tagggatcac cgacatcctg gtcattgccc
    30001 gcccgcagga cctaccgctg ttcgagcgac tgctcggcga cggcagccgc ttcggcgctt
    30061 gcttcgacta tgcggagcag gaaacccccc gtggcctggc ggacgcgctc atcgtcggcc
    30121 gggagcacgt cggtgacgac gatgtcgccc tcatcctcgg ggacaacatc ttccacggtc
    30181 acgacttcgg ctccatcgtg gccgacgcca tcaagaacaa cgtcggcgcg acgctgttcg
    30241 cctatgaggt ctctgacccg gaacgctacg gggttgtccg ggtcgaccgc ttcggcacgc
    30301 tgctcgacgt ggtcgagaag ccgagcaacc ccccgagcaa cctggcgata accggcttct
    30361 acctgttcga caacgacgcg ctcgatgttg cggccggcct ttcaccctcg ccccgtggcg
    30421 agttggagat cacggatgtg atcaagcact tcgtcgaccg gggcctcgct cgggcggttc
    30481 cgctgaccga cggcttcgtc tggctggacg ccggtacccc ggactcctat gtcgacgcct
    30541 gcaactacgt gcaggccatc gagacccggc agggacgcat gatcgcctgc ccggaggaag
    30601 tcgccttcgt caagggcctg acaggtgagg accaattgct cgcagcggca gcggaattcg
    30661 ggtcctccga atacggacgg tacctgactc ggctcgccgg gcggttcatc gagaggagcg
    30721 cggcatgagg gtcgcggtga ccggcggcgc cggcttcatc ggctcgaact tcgtgcgtga
    30781 cctggtcggt gaacggttcg cggccctcga tgtgcagcac gtcgtggtgc tcgacaacct
    30841 cacctatgcg ggcaccctcg acaatctcac aggcgtgctc gacgatgtcg agttccaccg
    30901 cacggacatc tgcgacaccc aggcagtcac ccgtcagatc gtcggctgtg acgcggtcgt
    30961 gcatttcgcg gccgagtcgc acgtggaccg ctcgatctcg tccggcttgc ccttcatgcg
    31021 cagcaacgtg ctcggcactc aatccgtgct cgaggcggct gcggcggccg gcgcggccag
    31081 gttcgtgcac atctccactg acgaggtcta cggatcgatt ccggtcggtg cgacgggcga
    31141 ggacgccccg ctcgcgccga actcgccgta cgccgcatcg aaggcgggat ccgacctggt
    31201 tgctctcgcc ttcgcacgca cccacggtct gccggtcacc gtgaccaggt gttcgaacaa
    31261 ctacggcccg taccagaacc ccgagaaggc gataccgcat ttcgtcacga cgctgctgcg
    31321 cggcggcgac atcccgctct acggggctgg gacgaacgtg cgcgactggc tgcatgtcgg
    31381 cgaccacgga aaggccgttg cgttgctgct cgccggcacg cccaaggaac aggtgtacaa
    31441 catcgggggt ggccaccaga tcaccaattt gcagctggcc cacatcattc tcgacgaact
    31501 cgggctcgat gcggacaggg tctccttcgt ccccgatcgg aaggcccacg acgcgcgcta
    31561 ctgcgtggac gactctcggc tgcgcgagga attcggctac cggccggagc gcgacttcgc
    31621 tgaggccatt cgggagacga tctcgtggta ctcggacaac cggagttggt ggacccatga
    31681 ctgacgcacg atctactcct gcgatggccc ggttggtgtc ggtgggcgag ccgccctcac
    31741 cgggctgtta cagagttgtg tgatcttgta ggcgggttgg tcagggcagg ccgatgaggt
    31801 cgagaggtcg gatatggggc ctgtaggaca tgtggcggag gccggcggcg atgcggccgt
    31861 gcccggcccg gcggagggtc tgcctttacc gcaccggggc ccaggttcgg tgaccccgtt
    31921 gggggcggct tccacttccg gggtgaggct gagcaaaggc gtggtcaccg cggtggtggt
    31981 tggccgtccg gcccgcgcag tgtgacgatc tgctgccggg ttgcttgcgc cgccggctgg
    32041 aatcagccgc agggcgacgc tcgtccggcg tagccttcgg gtcatggcag agagcaagcc
    32101 ccggaaggcc gcagcaccca agcaggccgc gaagcagtcg gctgtgaagc cgaagcagcc
    32161 ggagccgcac ctggcaatgg tgcggcgggc gcggaagatc aaccgcatcc tggcggagac
    32221 gtatccgtac gctcacccgg agctggactt cgagaacccc ttccagctgc tgatcgccac
    32281 ggtgctctcg gcccagacca ccgacctgcg cgtcaaccag accaccccgg cgctcttcgc
    32341 gaagtacccc acccccgagg acctggccgc cgccaacccg gagggggtcg aggagatcct
    32401 gcgcccctgc ggcttcttcc gggccaagac ccgctcggtg atagggctct ccaaggccct
    32461 caccgaggac ttcggcggcg aggtcccagg aaagctggag gacctggtca agctgccagg
    32521 agtcggccgc aagaccgcct tcgtggtcct cggcaacgcc ttcggacgcc cgggaatcac
    32581 cgtggacacc cacttccagc ggctggtgcg gcgctggaag tggaccgacg agaccgaccc
    32641 cgacaagatc gaggcggtcg tcggcgcgct gttcccgaag agcgactgga ccgacctgtc
    32701 ccaccacgtg atctggcacg gccgccgcat ctgtcacgcc cgcaagcccg cctgcggcgc
    32761 ctgccccatc gccccgctct gtccggccta cggcgagggc gagacggacc cggagaaggc
    32821 gaagaagctc ctgaagtatg agaagggcgg ctacccgggc cagcgcctga accctccgca
    32881 ggcctacctc gacgcgggcg gcaagccggc gccgccgctg ggggccggat gacggaacga
    32941 tctcggggct ctggggcgtt ggacacggca ggacgggggt gacgatgacg tacacgcacg
    33001 acacgcacag aggtccggtc atgctgagca aagagggtct gccgggctgg ctggacccgg
    33061 tggtgcgggc ggtggagacg gtcgaaccgc tccagctcag ccgcttcctg ccgccggaga
    33121 acggctcggg ccggcagtcg gccgtgctga tcctgttcgg cgacggcgag cacggccccg
    33181 agctgctgct catggagcgg gccggctccc tgcgctccca cgccggccag ccctccttcc
    33241 ccggcggcgc cctcgacccg gaggacggcg acgcgcacag cgacgggccg ctgcgggccg
    33301 cgctgcgcga ggccgaggag gagaccggcc tcgaccccgc cggcgtccag ctcttcggcg
    33361 tcctgcctgc cctctacatc ccggtcagcg gcttcgtcgt cacgcccgtg ctcggctggt
    33421 ggcgcgagcc cagcccggtc ggagtcgtcg acccgaacga gactgcccgt gtcttcaccg
    33481 tccccgtggc ggatctcacg gatcccgcca accgcgcgac caccgtccac cccagcggtc
    33541 accggggtcc ggcattcctg gtcgaatcgg ccctggtctg gggtttcacg gccggagtga
    33601 tcgaccgcct gctgcacttc gcgggctggg agcgcccttg gaacagggag aacgaggtcc
    33661 cgctcgactg gcggtcatga cagggtgtcg tccgtgaatg tgctggacat cttgttgctg
    33721 gtcgccgccg tgtggttcgc ggtcgtgggc tatcgccagg gtttcgtcgt cggcatcctg
    33781 tcggtgatcg ggttcctcgg cggtggtctc gtcgccgtat acacgctgcc cgtcatctgg
    33841 gacgccgtga ccgacaacgc ggaggtcggc accaccgcgg ccgtggtcgc cgtggtcgtc
    33901 gtcatcgtct gcgcctccat cggccaggcc ctgaccaccc acctcggcaa caagctgcgc
    33961 cgctacatca cctggtcccc ggcacgcgcc ctggacgcca ccggcggcgc cctcgtcaac
    34021 gtcgtcgcca tgctgctcgt cgcctggctg atcggatccg cgctcgccca gaccacgctg
    34081 ccgaccctgg gcaaggaggt ccgcaactcc aaggtgctcc tgggcgtgtc ggaggcgctg
    34141 cccgccgcgg ccgacacctg gttcaaggac ttcacctcgg tcctcgcgca gaacggcttc
    34201 ccgcaggtct tcagcccctt ctccaacgag ccgatcaagg acgtgcagcc gcccgacccg
    34261 gccctggcga acagcccggt cgccacccgg gcccagcgct ccatcgtcaa ggtcaccggc
    34321 accgcccaga gctgcggcaa ggtcctggag ggcaccggct tcgtcttcgc cgaccgccgc
    34381 gtcatgacca acgcgcacgt cgtcggcggc gtcgacgcgc cctccgtgca gatcggcggc
    34441 gagggccgca agtacggcgc gaaggtcgtc ctgtacgact ggaagcgcga catcgccgtc
    34501 ctcgacgtac cggacctgaa ggcgaacgcc ctccggttca ccacccagga cgcggccggc
    34561 ggcgacggcg cgatcgtcgc gggcttcccg gagaacggct cgtacgacgt ccgtgccgcg
    34621 cgcgtgcgcg ggcgcatcac ggccaacggc ccggacatct accaccgcgg cacggtcagc
    34681 cgcgacgtct actccctgta cgcgaccgtc cgccagggca actccggcgg cccgctgctc
    34741 acgcccgacg gcaaggtgta cggcgtggtg ttcgccaagt ccctcgacga cgccgacacc
    34801 ggctacgcgc tcacggccga cgagatcaag caggacatca gccaagggcg tgcggcgaac
    34861 gagcaggtgg gcaccgacag ctgcgccctg taggggtgtt ggggaagcgt cccgcgcggt
    34921 tcagccgcgc gggtgacgca ggcgcacgga gacccagcgg gcccggcggc gcaggatgcg
    34981 cggaattccc accctgaggt ccgcctccgc gagctgcgga gcgcctcgct gtgaggagct
    35041 cggcccagcg gccgagcggc ggttgcgggg tgcgtcactg tagtcgtgcg tccagcccat
    35101 accccgacgt gtgcccctgc cccaaggtcg ataaccgcct ccgcgccccc caattggcct
    35161 atgcggcagg catgtggccg ttcgatggac aagtgttcag gaaccggata ctccactcac
    35221 cgaaccgctt accggtccgg ctcgggatcc ttcagccagt tgatgagttc ggtggagaaa
    35281 gcggccggat cctcttcgtg cgggctgtgc cttcccgggg gctagtggca tcagcggctc
    35341 cgccgcgggc ccccggaccc ccagccgagt tcaggcggac gtcgtgtcac cggtccggct
    35401 cggggtcctt gagccagttg atcagctcgg aagagaaggc cgccgggtcc tcctcgtgcg
    35461 ggaaatgccc gagaccgtcg aacaggcgcc agcggtacgg ggcttcgacg tactcgcccg
    35521 agccggccgc gctgcgcgtc cgggtcaccg ggtccagtga gccgtgcaga tggagcgtcg
    35581 gcacccgaac cggccgcttc atcctgcggt tgaactggat gccgtccggg cgggccagcg
    35641 agcgcaccag ccagcggtac ggctcgatcg cgcagtgcgc ggtggacggg atgcacatgg
    35701 cccgctggta cgtctccacg tccgcgtcct ccggcagccg cggcccggac cactcccgga
    35761 tcagccggcc caccagcgcg ccgtcgtcgg cggtcagctg gcgctccggg atccacggcc
    35821 gctggaagcc ccagatgtag gagctggccg ccgtctgccg ggcgtcccgg agcatcgcgg
    35881 agcgccagcg ccgggggtgc ggcatcgaca cgaccgcgag ccgtcgtacg agcttgggcc
    35941 gcatcgccgc cgccgtccac gccagatagc cgcccaggtc gtgcccgacc agcgcggcgt
    36001 ccggctcgcc gagcgagcgg atgacgccgg tgacgtccag ggcgaggttg gccgggtcgt
    36061 acccgcgcgg ggtgcggtcg ctgccgccga caccgcgcag gtccatggcc accgcccggt
    36121 atcccgcgtc ggcgagcgcg accaactggt gccgccacgt ccaccagaac tgcgggaagc
    36181 cgtgcagcag cagcaccagg ggtccgtcgc cgagttcggc gatgtggaag cgcgcgccgt
    36241 tggcggcgac gtcccggtgc gtcaccttct ccccgtgggg gaggtcgatc ctcacggccg
    36301 atgtcgcggc gggctccgtc atgacgacga gcgtgccaca gcctcgatgg cctcgggcgc
    36361 ccggtcctgc ggcagctccg ggcgcgggtg cggcttggcg ttctgcagga cgcccgccgt
    36421 ctccttcatc gacgcggcga ccatctgcgg accctggctc ttcttgagct tcttcgcgaa
    36481 cgccatgccg atgagcgtga gcaggccggc gaccagcacg ttcgccgcga aggacagcac
    36541 gaagcagatg gcgaggttcc agccggtcca ggtccgaatg ccgtacgcca gagcgaagtt
    36601 gagcatcggc agggagaaga gcagcaccat gccggccgcc ccgaacgcgc cgccgctcgt
    36661 cgcgccgcgc ttgacgtcct gcctgagctg ggccttggcc agcgcgatct cgtcgtgcac
    36721 cagcgccgac atttcggtcg tcgccgaggc gaccagctgg ccgatgctgc gttcggcgcc
    36781 gaccgggctg ccgtcgggtg cgctcatcgc gttctccctc tgaagtcgta tctgccgtct
    36841 tgatttgtac cgtctcgtca gatcatgccg gacgaccgtc ctcctcgcct gccccgcccg
    36901 gcacttccgc acccccgtgg cgcgccgcgg cggccttctc ggcggcgatg cggcggtgct
    36961 cggcggcctt gcgctcgaag atgtccgcca tccgcaggtg gtaggccggg tcgtcctgct
    37021 cgtagacgtc cggaatgccg tcccggtcct cgtcgcgctc ctcgtcctcg cacagcccgc
    37081 gatagcgggc gttgcgtatc ttcagcagca ccgtggcaca cagggccgcg atcagcgatc
    37141 cggtgaggac ggccgccttc acctcgtcgg tcagcagcgt gtcgcccgcg aaggccagct
    37201 cgccgatgag cagcgagacg gtgaagccga ttccggcgag ggaggccacc gcgaagatgt
    37261 cggcccattc caggtcctcg ctgagctccg cgtgggtgaa gcgggccgtc agccaggtgc
    37321 tgccgaagat gccgagcgtc ttgcccacga ccagcccgag caccacccca agcgtctccg
    37381 gctcggtgaa cacatccccg agcgccccgc cggagaccac caccccggcg ctgaacagcg
    37441 cgaacagcgg tacggcgagc ccggccgaca gcggccgcac caggtgctcg atgtgctcgc
    37501 ccggcgagtg ctcctcaccc tcacgggtgg tgcagcgcag catcaggccc atcgccacgc
    37561 ccgcgatggt ggcgtgcacg ccgctgttgt acatcagcgc ccagacgacg acggccagcg
    37621 gcacgtacac gtaccagccg cgtacgccct tgcgcagcag cagccagaag accgccagcc
    37681 cggcgacggc cccgccgagc gccgcgaagt tgatccgctc ggtgaagaag atcgcgatga
    37741 tcaggatcgc gaacaggtcg tcgacgaccg cgagggtgag caggaaggcg cgcagggcgc
    37801 tgggcagcga ggtgccgatg accgcgagga cggcgagcgc gaaggcgatg tcggtggcgg
    37861 tgggcaccgc ccagccctgg gtggagccgt gtccggtgag gttggtgagg gtgtagacga
    37921 gcgccggtac ggccatcccg cacagcgcgg ccaccacggg cagcaccgcc gccctggggt
    37981 cgcgcaggtc cccggcgacc agctcgcgct tgagctcgat gccggcgacg aagaagaaga
    38041 cggcgaggag gccgtcggcg gcccagtggg ccacggacag gttcaggccg agggcgctcg
    38101 ggccgaagtg gaagtggctg accgcctcgt agctgtgctg cagtgcgggg atgttcgccc
    38161 agaccagcgc cgtcaccgtg gcgacgagaa gcaggacacc gccgacggtc tcggtgcgca
    38221 gcgcgtccgc gacgaaggtc cgctcgggca gggacaggcg tccgagaacc ttgcgggcgg
    38281 tgttcggggt gcggggcgcg gccacggcgg ggacctccgg gtcggtgggc aggacggagc
    38341 gcttgccgac cagacttccc ggcacacctt gaggatcgtt tcgcgttgga gttttgctta
    38401 gtttacctaa ggttgccgcg ggatgcatcc ggtgatccgt acgatatgcg cgtcaagcgc
    38461 aaaaggagcg cccggcgagt tgtcgccggg cgccccttcg gccgtaggcc ctagtcctcg
    38521 ctcggcgccg ccgggagctt ggcctggatg aagtccatga ccgtggagtc ggtcagcgtg
    38581 gtgacgtcac ccagctgacg gttctcggcc acgtcccgca ggagccggcg catgatcttg
    38641 ccggagcggg tcttcggcag ctcggccacc ggcaggatcc gcttcggctt ggcgatcgct
    38701 ccgagcgtgg cgccgacgtg gtcgcgcagc tggctgatca gcttgtcgtc ctcggacgcc
    38761 gtaccgcgca ggatgacaaa ggcgacgatg gcctggccgg tggtctcgtc ggtggcaccg
    38821 acgacggccg cctcggccac cgaggggtgc gagacgagcg ccgactccac ctcggtggtg
    38881 gagatgttgt gcccggacac cagcatgacg tcgtccaccc ggcccagcag ccagatgtcc
    38941 ccgtcgtcgt ccttcttcgc gccgtcaccg gcgaagtact tgccctcgaa gcgcgaccag
    39001 taggtgtcga tgaaccgctg gtcgtcgccc cagatggtgc gcagcatcga cggccacggc
    39061 tcggtgagga ccaggtagcc accgccgccg ttgggcacct cgttcgcctc gtcgtcgacg
    39121 acggtcgcgg agatgccggg cagcgggcgc tgcgccgaac cgggcttggt ctcggtcacg
    39181 ccgggcagcg gcgagatcat catcgcgccg gtctcggtct gccaccaggt gtccacgacc
    39241 ggcgtccggt cggcgccgat gtgcttgcgg taccagaccc aggcctcggg gttgatcggc
    39301 tcgcccacgg agccgaggac ccgcagggac gacaggtcga actgcgcggg gatgtcgtcg
    39361 ccccacttca tgaacgtccg gatcgcggtc ggcgcggtgt agaggatcgt gacccggtac
    39421 ttctccac
//
