BGC0000271 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0000271 (Streptomyces avermitilis)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 1	T2PKS	1	11,118	High	spore pigment	PKS

BGC0000271 - Region 1 - T2PKS

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Location: 1 - 11,118 nt. (total: 11,118 nt) Show pHMM detection rules used

Region on contig edge.

T2PKS: (t2ks and t2clf)

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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Gene overview

MIBiG

Tailoring

MIBiG comparison

KnownClusterBlast

NRPS/PKS domains

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 11,119
Label		BGC0000271

Tailoring functions

Oxidoreductases: oxygenase

BAB69162.1: monooxygenase FAD-binding

smcogs: SMCOG1050: monooxygenase FAD-binding

Transferases: methyltransferase

BAB69170.1: O-methyltransferase

smcogs: SMCOG1042: O-methyltransferase

Lyases: cyclase

BAB69168.1: cyclase/dehydrase

smcogs: SMCOG1128: cyclase/dehydrase

BAB69169.1: Polyketide synthesis cyclase

smcogs: SMCOG1225: Polyketide synthesis cyclase

Ligases: synthase

BAB69165.1: Beta-ketoacyl synthase

smcogs: SMCOG1022: Beta-ketoacyl synthase

BAB69166.1: Beta-ketoacyl synthase

smcogs: SMCOG1093: Beta-ketoacyl synthase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000271.5	1.00	PKS	spore pigment	Streptomyces avermitilis
BGC0000272.3	0.73	PKS	spore pigment	Streptomyces collinus
BGC0000215.5	0.70	PKS	curamycin	Streptomyces cyaneus
BGC0000231.5	0.61	PKS	griseusin A, griseusin B	Streptomyces griseus
BGC0001513.3	0.59	PKS	anthrabenzoxocinone	Actinobacteria bacterium
BGC0000234.5	0.58	PKS	jadomycin	Streptomyces venezuelae ATCC 10712
BGC0001197.5	0.57	PKS	frankiamicin	Frankia sp. EAN1pec
BGC0000275.4	0.54	PKS	tetracenomycin C	Streptomyces glaucescens
BGC0000221.5	0.52	PKS	erdacin	uncultured soil bacterium V167
BGC0001366.5	0.52	PKS	BE-24566B, zunyimycin A	Streptomyces sp. FJS31-2

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000271.5	1.00	PKS	spore pigment	Streptomyces avermitilis
BGC0000272.3	0.73	PKS	spore pigment	Streptomyces collinus
BGC0000215.5	0.70	PKS	curamycin	Streptomyces cyaneus
BGC0000231.5	0.61	PKS	griseusin A, griseusin B	Streptomyces griseus
BGC0001513.3	0.59	PKS	anthrabenzoxocinone	Actinobacteria bacterium
BGC0000234.5	0.58	PKS	jadomycin	Streptomyces venezuelae ATCC 10712
BGC0001197.5	0.57	PKS	frankiamicin	Frankia sp. EAN1pec
BGC0000275.4	0.54	PKS	tetracenomycin C	Streptomyces glaucescens
BGC0000221.5	0.52	PKS	erdacin	uncultured soil bacterium V167
BGC0001366.5	0.52	PKS	BE-24566B, zunyimycin A	Streptomyces sp. FJS31-2

Similar known clusters from MIBiG 4.0

Detailed domain annotation

Selected features only

Show module domains

Type II PKS

Type II PKS gene cluster prediction details

Cluster section:: 0 to 11118
Starter unit(s):: acetyl-CoA (Score: 0.0; E-value: 0)
Product class(es):: pentangular polyphenol
tetracenomycin

BAB69162.1: OXY (Score: 259.2; E-value: 1.9e-79)
BAB69164.1: CYC C5-C18 (Score: 215.2; E-value: 5.5e-67)
BAB69165.1: KS (Score: 724.1; E-value: 1e-220)
BAB69166.1: CLF (Score: 555.0; E-value: 2.2e-169)
BAB69167.1: ACP (Score: 76.7; E-value: 2.5e-24)
BAB69168.1: CYC C9-C14 (Score: 253.7; E-value: 1.1e-78)
BAB69169.1: CYC C4-C21/C2-C23|C2-C19 (Score: 163.5; E-value: 3e-51)
BAB69170.1: MET C6|C8 (Score: 521.6; E-value: 1.6e-159)