LOCUS       BGC0000277             11790 bp    DNA     linear   BCT 07-FEB-2000
DEFINITION  Streptomyces fradiae strain T#2717 urdamycin biosynthetic gene
            cluster, partial sequence.
ACCESSION   BGC0000277
VERSION     BGC0000277
KEYWORDS    .
SOURCE      Streptomyces fradiae
  ORGANISM  Streptomyces fradiae
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
COMMENT     ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2024-10-17 13:18:22
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11790
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..11790
                     /db_xref="taxon:1906"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces fradiae"
                     /strain="T#2717"
     subregion       1..11790
                     /aStool="mibig"
                     /contig_edge="True"
                     /label="PKS"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..11790
                     /contig_edge="True"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     CDS             238..684
                     /codon_start=1
                     /gene_functions="regulatory (smcogs)
                     SMCOG1167:transcriptional regulator (Score: 93.5; E-value:
                     7.4e-29)"
                     /gene_kind="regulatory"
                     /note="Urd-Orf148; uses GTG start codon"
                     /product="unknown"
                     /protein_id="AAF00212.1"
                     /transl_table=11
                     /translation="MTHPTVGHPAGLPDDPRADVTAPTPECPVEITLAALHGRWTTLVI
                     RELLRGDHSYSELRAALPVMSDKVLSDRLAHLTRAGVVDRDRRPSWPPRVRYTLTPNGH
                     RLGPVLQALWDWGAYGEEPRSTGDDPVGLRELPVHPKADGAARC"
     CDS             complement(755..1822)
                     /codon_start=1
                     /note="Urd-Orf355"
                     /product="unknown"
                     /protein_id="AAF00213.1"
                     /transl_table=11
                     /translation="MDANDLASVVTQMISGLATSVGAGVGTAAGEEVSRLVRERLGGSE
                     EGRTALARLDEEPGSGEAQTQLRTVLARSLADDPDFAARVEGAASRNTLHSGRDMTVQT
                     VSVSGSTVKGTINIGPLTITKSPGGYLALGAAVVVLALLIAFGTYGTVRVITLEDSPDT
                     RPTGSTTTPHAGSGPRLEPVMTKNAAKAAMPDQSALPAGWSAAGEPDVVTASEAGYPVD
                     PGGPALSGGTELRGPDYGISLEMEFFETAASAAKKFNRSDILAGWDIDQHSESLEMPKT
                     GDESLAFIDYTPSDYVTGMVTAARIGTVVCQVASWDTAKPADHAAEVFAFTRMCVQRAE
                     QAQQGRTPDAVVVTG"
     gene            3332..4612
                     /gene="urdGT1a"
     CDS             3332..4612
                     /codon_start=1
                     /gene="urdGT1a"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     oligosaccharide: MGT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1062:glycosyltransferase, MGT family (Score: 359.6;
                     E-value: 4.3e-109)"
                     /gene_kind="biosynthetic"
                     /note="UrdGT1a; uses TTG start codon"
                     /product="glycosyl transferase"
                     /protein_id="AAF00214.1"
                     /sec_met_domain="MGT (E-value: 2.6e-135, bitscore: 440.7,
                     seeds: 193, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVLFSIMPATAHLYPIVPLAWALQASGHEVRVASHPDMAATITA
                     AGLTAVSVGRPADLGALMRDGASDQCLEQITEALEIGSDDLNLRNAIRYYTLAGVSLYF
                     PTDPQRAESDRAVDDLVAFARSWRPDLVLWDPLVLAAPVAARLSGAAHARVLYGLDYVG
                     WAQQRFTERIGRRAQPLTEHPLAELMRPTLRRFGLDFDAELAVGQWTLDLLPERMRLPV
                     DLRYTALRRVPYTGTTTVPQWLYDEPKRPRVCLTLGMSTRKFLSGHGASPIADIFGLVE
                     ELDIELVATVNSAQLADVEELPDRVRIVDYLPLDLLLPTCSAVVHHGGGGTFAAAVAHQ
                     VPQLIPAPGEGGDRVAFARYVEQRGAGLTVSRTDYSADVFAEQLFRVLHEPSFQDGAAG
                     LHDDMLATPSPRDVVPVLEKLSDRYRR"
     gene            4629..5795
                     /gene="urdGT1b"
     CDS             4629..5795
                     /codon_start=1
                     /gene="urdGT1b"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     oligosaccharide: MGT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1062:glycosyltransferase, MGT family (Score: 318.4;
                     E-value: 1.4e-96)"
                     /gene_kind="biosynthetic"
                     /note="UrdGT1b"
                     /product="glycosyl transferase"
                     /protein_id="AAF00215.1"
                     /sec_met_domain="MGT (E-value: 9.5e-123, bitscore: 399.4,
                     seeds: 193, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVLMMSTPAPTHFTPLVSLAWALRGSGHEVVVAGQPDVLGAVAS
                     AGLNAVNVGDWFHVDDMLVAGLREGERPLETRPRASLESMGGYGRVWMTHARYLVGRYM
                     EFARIYGPDLIVSDPLEYSSLLVGGVLGVPVVQQRWGVDLISGPARAEARPGFGPLCER
                     LGLAGLPDPAVLLDPCPPGLQAPGAEPGSPIRFVPFNGNGVVPGWLREPRSASRPRVVV
                     TLGSRTLALNGVPLMRGILRAFEELPEVEAVATVDEVFREKVGPVPANVRMVDPVPLHL
                     VLDGCAAVVHHGGAGTTMTAGAFGLPQLVLPQLADQFGHGDRVSEVGAGISLDDAESQN
                     DSHRLAVELRRLLAEPEFAKAARALADSVRDMPAPAQVAADLTRLAGL"
     gene            complement(5846..7048)
                     /gene="urd-Int"
     CDS             complement(5846..7048)
                     /codon_start=1
                     /gene="urd-Int"
                     /gene_functions="other (smcogs) SMCOG1237:transposase
                     (Score: 443.4; E-value: 1.4e-134)"
                     /gene_kind="other"
                     /note="Urd-Int; uses GTG start codon"
                     /product="integrase"
                     /protein_id="AAF00216.1"
                     /transl_table=11
                     /translation="MNERKTQVWAGVDAGKGHHWTAVVDETGATLWSKKVDNDESAILT
                     ALGEILDLADEVHWAVDISGTSSALLLALLAAHGQQAVYVPGGTVNRMSGAYRGEAKTD
                     ARDTYVIAETARHRNDFTAIDVPAQLAVDLALLTAHRTDLVADRVRMINRLRDVLTGVF
                     PALERAFDYSAHKGALVLLTGYQTPAAIRRRGRARLTAWLANRGVRGADAVAETALAAA
                     QAQQTALPGEDVAAQIVAELAGQLLALDDRMKRIDKQIRETFRSHPQAEIIDSLPGMGP
                     ILGAEFVVAVGDLSAYADAGHLASAAGLVPVPRDSGRRTGNLHRPKRYSRRLRRVFYMS
                     AQTSMTREGPNRDFYLKKRGEGCQHIQAVIALARRRASVLWALLRDNRVFTPAPPVTQA
                     A"
     gene            7262..8437
                     /gene="urdGT1c"
     CDS             7262..8437
                     /codon_start=1
                     /gene="urdGT1c"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     oligosaccharide: MGT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1062:glycosyltransferase, MGT family (Score: 317.8;
                     E-value: 2.2e-96)"
                     /gene_kind="biosynthetic"
                     /note="UrdGT1c"
                     /product="glycosyl transferase"
                     /protein_id="AAF00217.1"
                     /sec_met_domain="MGT (E-value: 1.9e-121, bitscore: 395.1,
                     seeds: 193, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVLFLVTPSPTHFTPLVSLAWALRGAGHEVVVAGQPDVLGAVAS
                     AGLNAVSIGAPFNGEAKLLAGLGPDQRPLEVRPRPAPESMGGYGRVWMTHARYLVGRYM
                     EFARIYGPDLIVSDPLEYSSLLVGGVLGVPVVQQRWGVDLISGPARAEARPGFGPLCER
                     LGLAGLPDPAVLLDPCPPGLQAPGAEPGSPIRFVPFNGNGVVPGWLREPRSASRPRVLV
                     TIGGTLALNGVPLMRGILRAFEELPEVEAVATVDEVFREKVGPVPANVRMVDPVPLHLV
                     LDGCAAVVHHGGAGTTMTAGAFGLPQLVLPQLADHFGHGDRVSEVGAGISLDDAESQND
                     SHRLAVELRRLLAEPEFAKAARALADSVRDMPAPAQVAADLTRIAGVVGAL"
     gene            complement(8557..9120)
                     /gene="urdK"
     CDS             complement(8557..9120)
                     /codon_start=1
                     /gene="urdK"
                     /gene_functions="regulatory (smcogs) SMCOG1057:TetR family
                     transcriptional regulator (Score: 85.3; E-value: 1.2e-25)"
                     /gene_kind="regulatory"
                     /note="UrdK"
                     /product="regulatory protein"
                     /protein_id="AAF00218.1"
                     /transl_table=11
                     /translation="MTTPKSTRQKIQEVALELFVEQGYEKTSLRGIAERLNVTKPAIYY
                     HFQTKEAILISLFQDLGQPLAEIIAWAQEQPRTLETKKELLTRYSIALHNAAPLFRFMQ
                     ENQATVRQLSVGQDFKDRVGAMAGLIKEPGAPLADQVRCISALFTVHFGTFAMQELDGD
                     PEDKRQELLDVAIELVSTVHSGAV"
     gene            9248..10825
                     /gene="urdJ"
     CDS             9248..10825
                     /codon_start=1
                     /gene="urdJ"
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 432.2; E-value:
                     3e-131)"
                     /gene_kind="transport"
                     /note="UrdJ"
                     /product="transporter"
                     /protein_id="AAF00219.1"
                     /transl_table=11
                     /translation="MQYELAESGTSSSSQQPRGLRVSLVALLIAMLLATLDNLILGAAM
                     PTIVGELDGLDHLSWVVTAYALATAAATPIWGKLGDMYGRKVVFLAAIGVFLLGSALAG
                     ASQTMEQLIAFRAVQGLGAGGLMVGAFAIIGDIVPGRERGKYQGMMSAVMGLAMVAGPL
                     AGGLITDHLGWRWCFYINLPLGGVAICMVIAVLRLPKKRAQARIDYLGPILLAASISSL
                     VLMTTWGGGQYSWGSVQILGLGALVLVGGVLFVLVERRAAEPVLPLAVFRNSNFSLITA
                     VGFLLGFVQLGALTFLPLFLQTVQGASATNSGFLLFPVFGSMMVVNVIAGRVTTQTGKY
                     KIFLVVGQRLVCLGPFLLAQMDTGTSRVTSGVFMAVLGLGMGLLMQSVMLVALESVEKK
                     DLGVASSTATLSRTIGGSIGVAIMGALFTRQVQDSMAGRGPELSSAAGENMRLDAASLS
                     RLPQDIRSAYESAVASGTHQAFLLGAAAALVAFAASCFVREVPLRGAEEQENSAAAPRG
                     DQARVDEK"
     gene            10886..11479
                     /gene="urdO"
     CDS             10886..11479
                     /codon_start=1
                     /gene="urdO"
                     /product="UrdO"
                     /protein_id="AAF00220.1"
                     /transl_table=11
                     /translation="MSDAPVRLAVIIGSVREGRFGPTVANWFAGEAKQHDAFEVDVIDL
                     AEANLPGVLPAFGATPAPETVEAVGKVTPRLENADAFVVVTPEYNHSYPASVKTLIDWH
                     NAQWHAKPIGFVSYGGLSGGLRAVEHLRVVFAEVHAITIRDTVSFHSAWSQFDETGLPR
                     DPEGCTAAAQTLLGQLSWWARALREARTREPYKV"
ORIGIN
        1 ctgcaggcgg ccgttcgcgg cgtgcgactc cggcccggtc accggcgttc ccggctgcgg
       61 aaccagcacc gccgcgtcct cgtacacctg cgccaacgcg gtggcgtcac cgctgttgaa
      121 ccgctcggcg aacacggcgg gcacctcttc agggcgttcg gccaaagcgc gcatgatcga
      181 cacacatcct tccaagccgg gagaatcgaa gtgccccaca cgctaggagg cgatctcgtg
      241 actcacccaa cggttggtca ccccgcagga ctccccgacg acccgcgtgc cgacgtcacc
      301 gcccccactc ccgagtgccc ggtggagatc acgctggcgg ccctgcacgg ccgctggacg
      361 acgctggtga tccgcgaact gctgcgaggc gaccactcct acagcgaact ccgcgcggct
      421 ctgcccgtca tgtcggacaa ggtgctgtcc gaccggctgg cccacctcac ccgggcggga
      481 gtcgtcgacc gcgaccgccg cccgagctgg cccccacgcg tccgctacac cctcaccccg
      541 aacggccacc gcctgggccc ggtccttcag gccctgtggg actggggcgc gtacggggaa
      601 gagcctcggt ccacaggcga cgacccggtc gggcttcgtg aactccccgt tcatcccaaa
      661 gcagacggag ctgcacggtg ttgatggagt acccacccat cagttcccat ccgctccgaa
      721 cccccacttc atctcgtcgg cacgagcgat tcacctaccc cgtcaccacg accgcgtccg
      781 gcgtcctccc ctgctgggcc tgttcggcgc gctggacgca cattcgggtg aaggcgaaga
      841 cctcggcggc gtgatctgcg ggcttggcgg tgtcccacga cgccacttgg cacacgacgg
      901 tgccgatccg cgctgcggtg accatccccg tcacgtagtc ggagggggtg tagtcgatga
      961 aggccaagct ctcgtcaccg gtcttcggca tctccaggga ctcgctgtgc tggtcgatgt
     1021 cccatccggc gaggatgtcg gagcggttga acttcttcgc tgccgaggcc gcagtctcga
     1081 agaactccat ctccaggctg atgccgtagt cgggtcccct gagttctgtg ccgccggaga
     1141 gcgccgggcc gcccggatca accggatagc cagcctcact tgccgtgacc acatcgggct
     1201 cgccggccgc ggaccagccg gcaggcagag cggactggtc cggcatggcc gccttcgcgg
     1261 cattcttggt catgaccggc tccagtcggg gcccgctgcc ggcgtgcggc gtggtggtcg
     1321 aaccggtggg gcgcgtgtcc ggtgagtctt cgagggtgat tactcggacc gtgccgtacg
     1381 tgccaaaggc gattaataag gccagtacga cgacggcggc gccaagagca aggtatccgc
     1441 caggggactt cgtgatggtc aacggaccga tgttgatggt gccctttacg gtactgccgc
     1501 tgacgctgac cgtctgtacg gtcatgtccc tgcccgagtg aagcgtgttc cggctcgcag
     1561 cgccttccac tcgcgcagcg aagtccggat cgtcggcgag agacctcgcc aggaccgtcc
     1621 gcagctgggt ctgcgcttcg ccggatccag gttcctcatc aagccgcgcc agtgccgtac
     1681 ggccctcttc agacccgccg agccgctccc tgaccagcct ggacacctcc tccccggcag
     1741 ccgtccccac accggcgccc acgctggttg ccaggccact gatcatctgc gtcacgaccg
     1801 acgccaggtc attcgcatcc atgtgtcccc tccgcccctg tcacgccaac tcgaacatgt
     1861 ttccccgcgg gtggcttggc ctaccaccgt gcgaggacga ccgaccagcc ctcctcttcc
     1921 aaaacccata tcgcgacggg caggcggggc ttggtggccg tatccctggc gctcgcctac
     1981 gagcaacggg cagacggctt ccgccaccac ggtcgggatg gacctctgcg gtcctccgcg
     2041 agaagggacc catccggtga tcttcacgaa gctccatgag cttgcttgcc gccctcgacg
     2101 cagtggtggc cgctctcatg gctccgctgg acgaggacga ccggatgcag ggctgaaccg
     2161 atgcttccga agattcagga gtacatctcg atcaattgct cagtactgcg tcgccacggg
     2221 acgggtatgg cacccatgtc ctcgcttcga cgcgtggatg gagcatgagg gcgtgcagtc
     2281 cggtacgtac gcaaagaccc cggcatcagc gtctccgctg gtgacggggt ccaggtcaca
     2341 cttacacagt gtgcccccgg caggattcga acctgcgcac acggctccgg agccgtcgga
     2401 ttttcatacg ttttaccagg tcggcgggct gactgacggg ttgtcaggcc cgccgtcccg
     2461 catatagccc gcgaaaatta aatgccccat ttggtcgccc tgctcctggt tgattcgtcg
     2521 tgccagtcag cttgtgtcgc gtgatggaga tcatgaatgc cttttcaggg tagggcgtgg
     2581 gcaatcttcg cttcaatcga acgcgaaggc ggtcgagggc gcgcgggcaa tcaagtgcgc
     2641 cgggtgtgcg cctggcctgg cggaacttcc ccgtgcaacg cctcaaactg ggccgcgaca
     2701 tccgcgccgc ggctctcccc tcatggtggg aacggcatca gtcagaggac tggatctgtg
     2761 gccccgtcgg tgagtgctta agccctgccc cggactgccc tgctgtcaat cgcgcaaccg
     2821 tagggcgaag aacggagttc gtcggcggct tgtcggcgct cctttgtgcg gccgtctttg
     2881 ggtagttcgt acggccccct gggcgtaccg cagcgcttca gatcgaggaa ctgttaagag
     2941 acgctgttgc tgttgccggt cgagagtgcc ctgaatctat ttgacgagga tttgacgctc
     3001 ttctgtagtc gagttgtaga aatgtaagca catttgacgg ttgctcgctt gtctcgtgag
     3061 ctgaaaccga agaggcttgt ttcagtatcc ggtgtcgtgc gttcttctcg gttctgacga
     3121 acgccttcat ttatagcgat ttgtgtcgtg tcgacacagt cacgaatcac ccgtaggcca
     3181 acaaatatcg cgagtcggaa cgctccttcg gtctccatcc gaacctccgg caaacacggc
     3241 acagacgcag catgcattcg tgcgacttgc ggtctgagcg ttccagcccc caagactcac
     3301 gtgcttcact ccagcgattg gagcagtctc tttgcgtgtc ctcttttcga tcatgccggc
     3361 aacagcgcac ttatatccga tagttccact ggcctgggcg cttcaagcta gtggccacga
     3421 ggtccgggtc gccagccacc ccgacatggc cgccaccata accgcggccg gtctgaccgc
     3481 tgtctccgtg gggcggcctg cggacctcgg ggccctcatg cgggacggcg cgagcgacca
     3541 gtgtttggag cagatcaccg aggccctgga aattggttcc gacgatctca atctgcgcaa
     3601 tgccatccgc tattacacgt tggcaggtgt ctcgctctat ttccccaccg atccgcagcg
     3661 ggccgagagc gaccgtgcgg tggacgacct ggtggccttc gcccggtcct ggcgacccga
     3721 tcttgtgctg tgggatcccc tggtcctggc ggctcccgtc gcggcccgac tcagcggagc
     3781 cgcgcatgcc cgtgtcctgt acgggctcga ctacgtcggc tgggcgcagc aacggttcac
     3841 ggagcggatc ggccgacggg cccagccgct cacggagcat ccgctcgcgg aactcatgcg
     3901 gccgaccctc cgacgcttcg ggctcgactt cgacgccgag ctggccgtcg gccagtggac
     3961 actcgatctg ctgcccgaac gcatgcggtt gccggtcgac ctgcgctaca cggcgctgcg
     4021 ccgagtcccg tacacgggca cgaccactgt tccgcaatgg ttgtacgacg agccgaagcg
     4081 cccgcgagtg tgcctcacac tgggcatgag tacacgcaag tttctttccg ggcacggtgc
     4141 ttcgccgatc gccgacatct tcggtctggt ggaggagctc gacatcgagc tggtcgccac
     4201 cgtgaactcc gcccagctcg ctgacgtgga ggaactcccc gaccgggtcc gcatagtgga
     4261 ctatctcccg ctcgatctcc tgctgccgac ctgctccgcg gttgtgcacc atggcggcgg
     4321 agggaccttt gcggcagcgg tcgcccacca ggtgccccag ctgatcccgg cacccgggga
     4381 aggcggggac cgggttgcct tcgctcggta tgtggagcag cgaggcgccg ggctgaccgt
     4441 gagccgtacc gattactcgg ccgatgtctt cgcggagcag ctgttccgcg tgctccacga
     4501 gccctcgttc caggacgggg cggccggact tcatgacgac atgctggcga caccgagccc
     4561 gcgtgacgtc gtgcctgtcc tggagaagct gtccgaccgc taccgccgct gacgcaggga
     4621 gtagttcgat gcgtgtactg atgatgtcaa cccccgcgcc gacgcatttc acgccgttgg
     4681 tgtcgttggc gtgggccctg cggggttcgg gccatgaggt ggtggtcgcg ggtcagccgg
     4741 atgtactggg ggcggtcgcc tcggccgggc tcaacgcggt gaacgtcggc gactggttcc
     4801 acgtggacga catgttggtc gccgggttgc gggaggggga gcgcccgctc gagacgcgtc
     4861 cccgtgcctc gctcgagtcg atgggcgggt acgggcgggt gtggatgacc catgcgcgtt
     4921 atctggtcgg gcggtacatg gagttcgctc gcatctacgg tccggatctg atcgtgtcgg
     4981 atccgctgga gtacagctcg ctgctggtcg ggggtgtgct gggggttccg gtggtgcagc
     5041 agcggtgggg ggtggatctg atctcgggtc cggcgcgtgc ggaggcgcgg ccggggttcg
     5101 gtccgttgtg tgagcgtctg gggcttgcgg ggctgccgga tccggcggtg ttgctggatc
     5161 cgtgtccgcc gggtctgcag gctccggggg cggagccggg cagtccgatc aggttcgttc
     5221 cgttcaacgg caacggggtg gtgccggggt ggctgcgcga gccgcggtcc gcatcacgcc
     5281 cccgtgtagt cgtcaccctg ggcagtcgga cgttggcgtt gaacggggtg ccgttgatgc
     5341 ggggcattct gcgggcgttc gaggagctgc cggaggtgga ggcggtggcg acggtggacg
     5401 aggtgttccg ggagaaggtc gggccggtgc cggccaatgt gcggatggtc gatccggtgc
     5461 cgctgcacct ggtgctggac ggatgtgcgg ccgttgtgca ccacgggggc gcgggtacga
     5521 cgatgaccgc cggggcgttc gggctgcccc agctggtact gccccagctc gccgaccagt
     5581 tcgggcacgg tgaccgggtg agcgaggtgg gtgccgggat ctcgctggac gatgcggaga
     5641 gccagaacga ttcgcatcgg ctggccgtgg aacttcggcg gctgttggcg gagccggagt
     5701 tcgccaaggc cgcccgcgcg ctggccgact cggtccggga catgcccgca cccgcacagg
     5761 tcgccgccga cctcacacgg ctggccggcc tgtgatgtca ggcccacggg cgttggagta
     5821 ccaaggagga gtctcaataa cgaagtcaag ctgcttgcgt gaccggcggg gcgggggtga
     5881 atacccggtt gtcacgcagc agggcccaca acacgctggc tcgtcggcgg gccagggcga
     5941 tgacggcctg gatgtgttgg cagccctcgc cgcgcttctt caggtagaag tcccggttcg
     6001 gtccttcgcg ggtcatgctc gtctgcgcgg acatgtagaa caccctgcgc aggcgtcggc
     6061 tgtagcgctt gggccggtgg aggttgccgg tccggcgacc ggagtcacgc gggacgggca
     6121 ccagcccggc cgccgatgcc aggtggccgg cgtcggcgta ggccgacagg tcgccgacgg
     6181 ccacaacgaa ctcggctccg agtatcgggc ccataccggg cagcgaatcg atgatctccg
     6241 cctgcggatg actgcggaac gtctcgcgga tctgcttgtc gatgcgcttc atccggtcgt
     6301 ccagggccag gagctgcccg gccagttcgg ccacgatctg tgcggcgacg tcctcaccgg
     6361 gcagcgcggt ctgctgggct tgggctgctg ccagtgcggt ctcggcgacc gcgtcggccc
     6421 cacgcacgcc gcggttggcc agccaggccg tcagcctcgc ccggccgcgg cggcggatcg
     6481 cggccggggt ctggtagccc gtcagcagga cgagcgcgcc tttgtgggcc gagtagtcga
     6541 aagcccgctc cagtgcgggg aagacgccag tcagcacgtc gcgcaggcgg ttgatcatcc
     6601 gcacgcggtc ggccaccaag tcggtgcggt gggcggtcag cagcgcgagg tcgacggcca
     6661 gctgggcggg cacgtcgatg gcggtgaagt cgttgcggtg gcgggcggtc tcggcgatga
     6721 cgtaggtgtc acgggcgtcg gtcttggcct cgccccggta tgcgcccgac atgcggttga
     6781 ccgtgccgcc aggcacgtag acggcctgct ggccatgggc cgcgagcagg gccagcagca
     6841 gcgcggagga cgtgccggag atgtcgaccg cccagtggac ctcgtcggcc aggtccagga
     6901 tctcgccgag cgccgtcagg atcgccgact cgtcgttgtc gaccttcttc gaccacaggg
     6961 tcgcgccggt ctcgtcgacc accgccgtcc agtggtggcc cttgccggca tcgacaccgg
     7021 cccagacctg ggtcttccgc tcgttcactc gcccctcctc aaaccatccg gcatgccgtc
     7081 ggcccgagga acacccccgc tgtcatctcc gtaatcagcg accgcacaag gcgcgcacat
     7141 ctcaatcagc agccagggcg ccccggagag ccgggcggcc actcctgctg agccactgaa
     7201 gacaagaacc catcagccac acccggccct cccgggccgc ccaacaactt acggagaccc
     7261 catgcgagtc ctgtttctgg tgacaccctc gccgacgcat ttcacgccgt tggtgtcatt
     7321 ggcgtgggcc ctgcggggtg cgggccatga ggtggtggtc gcgggtcagc cggatgtact
     7381 gggggcggtc gcctcggccg ggctcaacgc ggtgagcatc ggcgcaccgt tcaacgggga
     7441 ggcgaagctg ctcgccggac tgggccccga tcagcggccg ctggaggtac ggccccgccc
     7501 ggcgcctgag tcgatgggcg ggtacgggcg ggtgtggatg acccatgcgc gttatctggt
     7561 cgggcggtac atggagttcg ctcgcatcta cggtccggat ctgatcgtgt cggatccgct
     7621 ggagtacagc tcgctgctgg tcgggggtgt gctgggggtt ccggtggtgc agcagcggtg
     7681 gggggtggat ctgatctcgg gtccggcgcg tgcggaggcg cggccggggt tcggtccgtt
     7741 gtgtgagcgt ctggggcttg cggggctgcc ggatccggcg gtgttgctgg atccgtgtcc
     7801 gccgggtctg caggctccgg gggcggagcc gggcagtccg atcaggttcg ttccgttcaa
     7861 cggcaacggg gtggtgccgg ggtggctgcg cgagccgcgg tccgcatcac gcccccgtgt
     7921 actcgtcacc atcggtggca cgttggcgtt gaacggggtg ccgttgatgc ggggcattct
     7981 gcgggcgttc gaggagctgc cggaggtgga ggcggtggcg acggtggacg aggtgttccg
     8041 ggagaaggtc gggccggtgc cggccaatgt gcggatggtc gatccggtgc cgctgcacct
     8101 ggtgctggac ggatgtgcgg ccgttgtgca ccacgggggc gcgggtacga cgatgaccgc
     8161 cggggcgttc gggctgcccc agctggtact gccccagctc gccgaccact tcgggcacgg
     8221 tgaccgggtg agcgaggtgg gtgccgggat ctcgctggac gatgcggaga gccagaacga
     8281 ttcgcatcgg ctggccgtgg aacttcggcg gctgttggcg gagccggagt tcgccaaggc
     8341 cgcccgcgcg ctggccgact cggtccggga catgcccgca cccgcacagg tcgccgccga
     8401 cctcacacgc atcgcgggtg tcgtcggcgc cctctagccg gccctcgatg tcgtacgtct
     8461 gtacgtgcgc tgcgggctcc ggcgttcgcc cgtcgaagga cgctggagcc cgcagcagtc
     8521 ggctccgtca tcggagccgt accgggacga tctggctcac actgcccccg agtgcaccgt
     8581 cgagaccagc tcaatggcga catcgagcaa ctcctggcgc ttgtcctcgg gatcgccgtc
     8641 cagttcctgc atcgcgaagg tgccgaaatg gacggtgaac agcgcgctga tgcagcggac
     8701 ctggtccgcg agcggggcac ccggctcctt gatcaggccc gccatggcgc cgacccggtc
     8761 cttgaaatcc tgaccgacac tgagctgtcg caccgtggcc tggttctcct gcatgaaccg
     8821 gaagagtggt gccgcgttgt gcagggcgat gctgtaccgg gtgagcagtt ccttcttcgt
     8881 ctccagagtg cggggctgtt cctgcgccca agcgatgatc tccgccagcg gctgccccag
     8941 atcctggaag aggctgatga gaatggcctc cttcgtctga aaatggtagt aaatggctgg
     9001 ttttgtcaca ttcagtctct cggcgatccc gcggagtgaa gtcttctcat agccctgctc
     9061 gacgaagagt tcgagggcga cttcctgaat cttctggcgg gtggacttgg gcgttgtcat
     9121 gatcgcgcct ccggatgctt acttgacggg cggcaagtgc cgtctgtact ctccagtgta
     9181 gcttgccgcc cggcaagtaa gtaccagttc caggggtgcg gcacactcgc ggagacatgt
     9241 ggagaccatg cagtacgaat tagccgaatc cggaacatcg tcgtcgagcc aacagccccg
     9301 tggcctgcgg gtctcgctcg tcgccctgct catcgccatg ttgctcgcca cgctggacaa
     9361 tctgatcctc ggcgcagcga tgccgaccat cgtcggcgag ctcgacggcc tcgaccatct
     9421 ctcctgggtg gtcacggcct acgccctcgc caccgcggcc gccacgccca tctggggcaa
     9481 gctcggggac atgtacggcc gcaaggtggt gttcctggcc gcgatcggcg tcttcctcct
     9541 cggatctgca ctcgccggcg cttcgcagac catggaacag ctcatcgcct tccgggccgt
     9601 gcagggtctg ggcgccgggg gactgatggt cggagcgttc gcgatcatcg gggacatcgt
     9661 ccccggccgt gagcggggca agtaccaggg catgatgtcg gcggtgatgg ggctcgccat
     9721 ggtcgccggc cctctggccg gtggcctgat caccgaccac ctcggctggc gctggtgctt
     9781 ttacatcaac cttcccctgg gcggcgtcgc catctgcatg gtcatcgccg tcctgcggct
     9841 accgaagaag cgggcgcagg cgcggatcga ctacctgggc ccgatcctgc tggccgcgtc
     9901 catcagttcc ctggtgctca tgaccacctg gggcggtggc cagtactcct ggggatcggt
     9961 gcagatcctg ggactcggtg ccctggtcct tgtgggtggc gtgctgttcg tgctcgtcga
    10021 gcgccgggcc gccgaaccgg tgctgccgct ggcggtgttc cggaactcga acttctccct
    10081 catcaccgcc gtcggctttc tcctcggctt cgtccagctc ggcgctctga cgttccttcc
    10141 gctcttcctg cagacggtgc aaggcgcttc cgccaccaac tccgggttcc tgttgttccc
    10201 cgtcttcggc tcgatgatgg tggtcaacgt gatcgcgggg cgggtgacca cacagacggg
    10261 caagtacaag atcttcctgg ttgtggggca gcgcctggtc tgcctgggac ccttcctcct
    10321 ggcgcagatg gacaccggca cctcccgcgt cacgtctggt gtcttcatgg ctgtgctcgg
    10381 cctggggatg ggtctgctga tgcagagcgt gatgctcgtc gccctggaga gcgtggagaa
    10441 gaaggacctc ggtgtcgcgt cgtccacggc gaccctgtcg cgcaccatcg gcgggtcgat
    10501 cggtgtggcg atcatgggtg cgctgttcac ccggcaggtg caggactcca tggcgggacg
    10561 cggacccgag ctctcctcgg cggccggcga gaacatgcgg ctggacgccg cctcgctgtc
    10621 ccgtcttccg caggacatcc gcagtgccta cgagtccgcg gtcgcctcgg gcacgcacca
    10681 ggccttcctg ctcggcgcgg cggcggcgct ggtcgcgttc gccgcctcgt gcttcgtcag
    10741 ggaagttccg ctgcgggggg cggaggagca ggagaacagc gctgccgccc cacgcggcga
    10801 tcaagctcgc gtcgacgaga aatgaatccc ttccgcggca cggctcgacc ggccgtcacc
    10861 gctgtccgaa cccaaaggag aactcatgtc tgatgctccc gtccgactcg ccgtcatcat
    10921 cggcagcgtg cgcgaaggac gtttcggccc gaccgttgcc aactggttcg ccggggaggc
    10981 gaagcagcac gacgccttcg aggtcgatgt gatcgacctt gcggaggcga atcttcccgg
    11041 cgtgctgccc gcgttcggag cgacgcccgc gccggagacg gtggaagcgg tgggcaaggt
    11101 cacgccgcgt cttgaaaatg cggacgcgtt cgtcgtggta actcccgaat acaaccacag
    11161 ctacccggcc tcggtgaaga ccctgattga ctggcacaac gcccagtggc acgccaagcc
    11221 gatcggtttc gtctcctatg gcggcctttc cggcgggctg cgcgcggtgg aacacctccg
    11281 cgtggtcttc gccgaagtgc acgcgatcac cattcgcgac accgtcagtt tccacagcgc
    11341 ctggtcgcag ttcgacgaga ccgggctccc cagggaccct gagggctgca ccgcggccgc
    11401 ccagactctg ctcggccagc tgtcgtggtg ggcgcgggcg ctccgtgagg caaggactcg
    11461 cgagccgtac aaggtctgag aatccccgtc ccgtccgggt gccgcgcggg atcgattccg
    11521 gcgcggcacc ctgccttttg gccggtgacc tcgtcatctg tcatacccgg aaccaaactt
    11581 gacaattccc tgacgtgatt ctgttggtca tctgacatgg tggaccttga cgtttccggg
    11641 gcgactgaag aagctaatta ctagcttcca cagcactatg tcgatgcgcc ggtggtgaca
    11701 ccgccggtta ttgccaaatg tggcgtaccg aggaaattct cggtacgcca catttgcgtt
    11761 cagtcacttt gcaccccgga gggcacgcat
//
